SPRR2G

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of skin barrier (GO:0061436)9.73818855
2regulation of water loss via skin (GO:0033561)9.18399890
3* keratinocyte differentiation (GO:0030216)8.56660360
4hair cycle (GO:0042633)8.50728335
5molting cycle (GO:0042303)8.50728335
6peptide cross-linking (GO:0018149)7.49694079
7* epidermis development (GO:0008544)6.65520364
8keratinocyte proliferation (GO:0043616)6.45818194
9multicellular organismal water homeostasis (GO:0050891)6.40548677
10* epidermal cell differentiation (GO:0009913)6.16782744
11bundle of His cell to Purkinje myocyte communication (GO:0086069)5.92905475
12negative regulation of interferon-gamma production (GO:0032689)5.87759318
13skin morphogenesis (GO:0043589)5.76208652
14ectoderm development (GO:0007398)5.60150752
15long-chain fatty acid biosynthetic process (GO:0042759)5.50134787
16phosphatidylcholine acyl-chain remodeling (GO:0036151)5.34008063
17water homeostasis (GO:0030104)5.27656736
18negative regulation of interleukin-17 production (GO:0032700)5.08592659
19intermediate filament organization (GO:0045109)4.97559418
20sequestering of metal ion (GO:0051238)4.86116060
21positive regulation of cellular amide metabolic process (GO:0034250)4.85559744
22gap junction assembly (GO:0016264)4.75329821
23detection of external biotic stimulus (GO:0098581)4.61560815
24regulation of T cell chemotaxis (GO:0010819)4.59866949
25positive regulation of T cell chemotaxis (GO:0010820)4.59866949
26interferon-gamma secretion (GO:0072643)4.57690629
27cell-substrate junction assembly (GO:0007044)4.39165532
28citrulline biosynthetic process (GO:0019240)4.38264501
29ceramide biosynthetic process (GO:0046513)4.30467867
30linoleic acid metabolic process (GO:0043651)4.30437896
31defense response to Gram-negative bacterium (GO:0050829)4.12715621
324-hydroxyproline metabolic process (GO:0019471)4.11617484
33negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)4.04069238
34detection of biotic stimulus (GO:0009595)3.94569067
35detection of bacterium (GO:0016045)3.93837355
36lipoxygenase pathway (GO:0019372)3.69440188
37phospholipid catabolic process (GO:0009395)3.67314155
38positive regulation of epidermis development (GO:0045684)3.63632265
39regulation of transforming growth factor beta1 production (GO:0032908)3.62590430
40intermediate filament cytoskeleton organization (GO:0045104)3.62142275
41positive regulation of osteoblast proliferation (GO:0033690)3.55450097
42negative regulation of keratinocyte proliferation (GO:0010839)3.55105395
43positive regulation of cholesterol efflux (GO:0010875)3.53361547
44alditol phosphate metabolic process (GO:0052646)3.52311646
45intermediate filament-based process (GO:0045103)3.49131675
46detection of other organism (GO:0098543)3.46962705
47one-carbon compound transport (GO:0019755)3.38973532
48positive regulation of monocyte chemotaxis (GO:0090026)3.37754752
49planar cell polarity pathway involved in neural tube closure (GO:0090179)3.32550984
50cellular response to arsenic-containing substance (GO:0071243)3.28498608
51eyelid development in camera-type eye (GO:0061029)3.27689674
52phospholipid efflux (GO:0033700)3.19172433
53regulation of monocyte chemotaxis (GO:0090025)3.17163605
54* epithelium development (GO:0060429)3.16856646
55fatty acid elongation (GO:0030497)3.16674328
56regulation of ruffle assembly (GO:1900027)3.15995683
57phosphatidylserine acyl-chain remodeling (GO:0036150)3.14391607
58regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.13516378
59positive regulation of cholesterol transport (GO:0032376)3.11511552
60positive regulation of sterol transport (GO:0032373)3.11511552
61regulation of natural killer cell activation (GO:0032814)3.11411803
62positive regulation of epidermal cell differentiation (GO:0045606)3.09784093
63establishment of planar polarity (GO:0001736)3.08693628
64establishment of tissue polarity (GO:0007164)3.08693628
65regulation of toll-like receptor 4 signaling pathway (GO:0034143)3.08596486
66cytoskeletal anchoring at plasma membrane (GO:0007016)3.06519629
67positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)3.06385482
68polarized epithelial cell differentiation (GO:0030859)3.06212518
69decidualization (GO:0046697)3.05095241
70phosphatidylinositol acyl-chain remodeling (GO:0036149)3.04771701
71positive regulation of interleukin-8 secretion (GO:2000484)3.01233709
72epithelial cell-cell adhesion (GO:0090136)3.00389621
73regulation of neuron projection regeneration (GO:0070570)3.00041285
74regulation of axon regeneration (GO:0048679)3.00041285
75lateral sprouting from an epithelium (GO:0060601)2.98545215
76positive regulation of glomerulus development (GO:0090193)2.95728782
77wound healing, spreading of epidermal cells (GO:0035313)2.93104793
78phosphatidylglycerol metabolic process (GO:0046471)2.90429494
79regulation of keratinocyte differentiation (GO:0045616)2.88630931
80regulation of chemokine secretion (GO:0090196)2.88105689
81negative regulation of cell fate specification (GO:0009996)2.87702004
82maintenance of gastrointestinal epithelium (GO:0030277)2.86781788
83positive regulation of humoral immune response (GO:0002922)2.85412353
84lung lobe morphogenesis (GO:0060463)2.85010431
85regulation of skeletal muscle contraction (GO:0014819)2.82088910
86regulation of epidermis development (GO:0045682)2.78876475
87regulation of interleukin-17 production (GO:0032660)2.77356576
88skin development (GO:0043588)2.76304050
89response to fungus (GO:0009620)2.76144626
90peptidyl-proline hydroxylation (GO:0019511)2.74987302
91negative regulation of cell fate commitment (GO:0010454)2.74007579
92surfactant homeostasis (GO:0043129)2.72838676
93regulation of lymphocyte chemotaxis (GO:1901623)2.70674346
94citrulline metabolic process (GO:0000052)2.69838192
95fibrinolysis (GO:0042730)2.69648790
96* epithelial cell differentiation (GO:0030855)2.68812143
97sphingolipid biosynthetic process (GO:0030148)2.66365397
98phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.64843671
99regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.63851626
100positive regulation of p38MAPK cascade (GO:1900745)2.63083387
101wound healing (GO:0042060)2.61962184
102positive regulation of granulocyte chemotaxis (GO:0071624)2.61827090
103membrane budding (GO:0006900)2.60761943
104regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.59672755
105epithelial structure maintenance (GO:0010669)2.58932905
106cell adhesion mediated by integrin (GO:0033627)2.58273623
107phosphatidic acid biosynthetic process (GO:0006654)2.57654126
108phosphatidic acid metabolic process (GO:0046473)2.57654126
109response to UV-B (GO:0010224)2.57139884
110retinal metabolic process (GO:0042574)2.56974295
111regulation of natural killer cell differentiation (GO:0032823)2.56133417
112positive regulation of keratinocyte differentiation (GO:0045618)2.55559057
113response to vitamin D (GO:0033280)2.54707715
114positive regulation of vesicle fusion (GO:0031340)2.53462786
115cellular response to interleukin-4 (GO:0071353)2.53238792
116chemical homeostasis within a tissue (GO:0048875)2.53142916
117regulation of cell proliferation involved in kidney development (GO:1901722)2.52750268
118cellular response to vitamin D (GO:0071305)2.52606060
119sphingoid metabolic process (GO:0046519)2.51140934
120epithelial cell differentiation involved in prostate gland development (GO:0060742)2.50800250
121defense response to fungus (GO:0050832)2.49117558
122ventricular cardiac muscle cell action potential (GO:0086005)2.48589093
123defense response to Gram-positive bacterium (GO:0050830)2.47996437
124regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.46610549
125long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.45730646
126negative regulation of lymphocyte differentiation (GO:0045620)2.45639653
127regulation of hair cycle (GO:0042634)2.45314479
128regulation of endothelial cell chemotaxis (GO:2001026)2.44530752
129regulation of cellular amide metabolic process (GO:0034248)2.44462827
130hair follicle morphogenesis (GO:0031069)2.43480974
131regulation of keratinocyte proliferation (GO:0010837)2.43065099
132positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511)2.42049747
133peptidyl-arginine modification (GO:0018195)2.41302827
134negative regulation of stress fiber assembly (GO:0051497)2.40436365
135regulation of epidermal cell differentiation (GO:0045604)2.36314473
136keratinocyte development (GO:0003334)2.35520594
137phosphatidylserine metabolic process (GO:0006658)2.34118098
138diterpenoid biosynthetic process (GO:0016102)2.29339825
139wound healing, spreading of cells (GO:0044319)2.28408720
140mesodermal cell differentiation (GO:0048333)2.26563470
141phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.26410191
142endodermal cell differentiation (GO:0035987)2.22355433
143atrioventricular valve morphogenesis (GO:0003181)2.21986684
144sphingosine metabolic process (GO:0006670)2.18877474
145cell junction assembly (GO:0034329)2.18654710
146cell junction organization (GO:0034330)2.18569521
147response to zinc ion (GO:0010043)2.17783385
148regulation of epithelial cell differentiation involved in kidney development (GO:2000696)2.17411674
149antimicrobial humoral response (GO:0019730)2.15983228
150* keratinization (GO:0031424)16.0536024
151hemidesmosome assembly (GO:0031581)11.5147500
152desmosome organization (GO:0002934)10.1824699

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse5.81129040
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.56484572
3SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.43375861
4P63_26484246_Chip-Seq_KERATINOCYTES_Human2.53543390
5ESR1_21235772_ChIP-Seq_MCF-7_Human2.52527071
6RARG_19884340_ChIP-ChIP_MEFs_Mouse2.40497225
7SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.32016748
8SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.32016748
9ESR2_21235772_ChIP-Seq_MCF-7_Human2.31778867
10SOX9_24532713_ChIP-Seq_HFSC_Mouse2.02978166
11TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.01456864
12TP63_17297297_ChIP-ChIP_HaCaT_Human13.0031237
13HIF1A_21447827_ChIP-Seq_MCF-7_Human1.96409603
14SOX2_20726797_ChIP-Seq_SW620_Human1.95791706
15ESR1_15608294_ChIP-ChIP_MCF-7_Human1.91192692
16FOXO3_23340844_ChIP-Seq_DLD1_Human1.75825427
17KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.73721687
18ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.70749019
19ZNF263_19887448_ChIP-Seq_K562_Human1.64306385
20KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.64296734
21PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.61118764
22ATF3_27146783_Chip-Seq_COLON_Human1.60162956
23RACK7_27058665_Chip-Seq_MCF-7_Human1.57981097
24RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.54644580
25NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.53173275
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.52897979
27TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.51688203
28PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.48383210
29ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.44712871
30VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.43784349
31* ERG_20517297_ChIP-Seq_VCAP_Human1.42290646
32CLOCK_20551151_ChIP-Seq_293T_Human1.39811307
33ZNF217_24962896_ChIP-Seq_MCF-7_Human1.35958227
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.33928279
35FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.33798701
36CJUN_26792858_Chip-Seq_BT549_Human1.32275703
37TCF4_18268006_ChIP-ChIP_LS174T_Human1.30174403
38EGR1_19032775_ChIP-ChIP_M12_Human1.30012559
39PPAR_26484153_Chip-Seq_NCI-H1993_Human1.29386831
40KLF5_25053715_ChIP-Seq_YYC3_Human1.27290808
41JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.22990546
42SMC4_20622854_ChIP-Seq_HELA_Human1.18546808
43RUNX1_27514584_Chip-Seq_MCF-7_Human1.16773792
44* TP63_23658742_ChIP-Seq_EP156T_Human1.16284988
45STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.16112792
46CDX2_20551321_ChIP-Seq_CACO-2_Human1.15522566
47TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.15215351
48SOX2_27498859_Chip-Seq_STOMACH_Mouse1.15211307
49SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.14819917
50CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13955408
51CTCF_20526341_ChIP-Seq_ESCs_Human1.13055017
52UBF1/2_26484160_Chip-Seq_HMECs_Human1.12812813
53BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.12649296
54UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12569765
55GATA4_25053715_ChIP-Seq_YYC3_Human1.11707847
56ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.11547599
57JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.11455659
58E2F1_20622854_ChIP-Seq_HELA_Human1.10141373
59GATA3_24758297_ChIP-Seq_MCF-7_Human1.10112166
60P53_21459846_ChIP-Seq_SAOS-2_Human1.08406085
61GATA6_25053715_ChIP-Seq_YYC3_Human1.08279826
62LXR_22292898_ChIP-Seq_THP-1_Human1.05661880
63* TP63_22573176_ChIP-Seq_HFKS_Human1.03397884
64SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.99405457
65ELK3_25401928_ChIP-Seq_HUVEC_Human0.99237356
66BCOR_27268052_Chip-Seq_Bcells_Human0.98368467
67ESR1_20079471_ChIP-ChIP_T-47D_Human0.98337121
68RXR_22108803_ChIP-Seq_LS180_Human0.96652675
69* GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.95693367
70DNAJC2_21179169_ChIP-ChIP_NT2_Human0.94558995
71ERG_21242973_ChIP-ChIP_JURKAT_Human0.94545097
72FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.93920968
73RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.93037525
74P300_27058665_Chip-Seq_ZR-75-30cells_Human0.91945310
75FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.90086490
76ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.89138956
77SA1_27219007_Chip-Seq_ERYTHROID_Human0.88175817
78KDM2B_26808549_Chip-Seq_K562_Human0.86960254
79RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86830890
80GATA2_21666600_ChIP-Seq_HMVEC_Human0.86039851
81BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.85440705
82CTCF_27219007_Chip-Seq_Bcells_Human0.84865318
83TP53_20018659_ChIP-ChIP_R1E_Mouse0.84735321
84CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.83671827
85* GATA6_21074721_ChIP-Seq_CACO-2_Human0.82081513
86CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.81957262
87PPARA_22158963_ChIP-Seq_LIVER_Mouse0.80086773
88AUTS2_25519132_ChIP-Seq_293T-REX_Human0.80024166
89MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.78430155
90RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.78135216
91GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.77658322
92NCOR_22424771_ChIP-Seq_293T_Human0.77635526
93TP53_18474530_ChIP-ChIP_U2OS_Human0.77330890
94P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.76597860
95* CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.76234430
96AR_21572438_ChIP-Seq_LNCaP_Human0.76106764
97KDM2B_26808549_Chip-Seq_SUP-B15_Human0.75858478
98AHR_22903824_ChIP-Seq_MCF-7_Human0.75436238
99BCL6_27268052_Chip-Seq_Bcells_Human0.74054987
100* RBPJ_21746931_ChIP-Seq_IB4_Human0.71282892
101SUZ12_27294783_Chip-Seq_ESCs_Mouse0.70819710
102CSB_26484114_Chip-Seq_FIBROBLAST_Human0.70466972
103STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.70350532
104TAF2_19829295_ChIP-Seq_ESCs_Human0.70336712
105ZFP281_18757296_ChIP-ChIP_E14_Mouse0.69388177
106AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.69216846
107SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.68528270
108CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.68443892
109CEBPB_22108803_ChIP-Seq_LS180_Human0.67781759
110NRF2_20460467_ChIP-Seq_MEFs_Mouse0.67440862
111NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.67440862
112TBX20_22328084_ChIP-Seq_HEART_Mouse0.67343600
113TBX20_22080862_ChIP-Seq_HEART_Mouse0.67343600
114YY1_22570637_ChIP-Seq_MALME-3M_Human0.67205142
115FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.67063753
116FOXM1_26456572_ChIP-Seq_MCF-7_Human0.66549387
117PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.66373927
118IKZF1_21737484_ChIP-ChIP_HCT116_Human0.66214519
119EP300_21415370_ChIP-Seq_HL-1_Mouse0.66060860
120LXR_22158963_ChIP-Seq_LIVER_Mouse0.65762282
121GATA2_19941826_ChIP-Seq_K562_Human0.65361275
122CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.65330080
123ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.64971576
124JARID2_20075857_ChIP-Seq_MESCs_Mouse0.64838989
125KDM2B_26808549_Chip-Seq_DND41_Human0.64787064
126RXR_22158963_ChIP-Seq_LIVER_Mouse0.64778890
127HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.64614851
128NANOG_20526341_ChIP-Seq_ESCs_Human0.64516491
129MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.63889822
130* HNFA_21074721_ChIP-Seq_CACO-2_Human0.63530810
131SMAD4_21741376_ChIP-Seq_ESCs_Human0.63361218
132Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.63252601

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier7.17565342
2MP0010234_abnormal_vibrissa_follicle5.33580302
3MP0000579_abnormal_nail_morphology5.27735968
4MP0005275_abnormal_skin_tensile4.77891454
5MP0005501_abnormal_skin_physiology4.73495345
6MP0003453_abnormal_keratinocyte_physiol3.63967610
7MP0003941_abnormal_skin_development3.52127246
8MP0000467_abnormal_esophagus_morphology3.45075861
9MP0001216_abnormal_epidermal_layer3.37552904
10MP0002060_abnormal_skin_morphology3.16710543
11MP0010678_abnormal_skin_adnexa3.00443259
12MP0010771_integument_phenotype2.98696803
13MP0005377_hearing/vestibular/ear_phenot2.91708030
14MP0003878_abnormal_ear_physiology2.91708030
15MP0003705_abnormal_hypodermis_morpholog2.89460233
16MP0000383_abnormal_hair_follicle2.89059329
17MP0003566_abnormal_cell_adhesion2.63316463
18MP0004947_skin_inflammation2.50826396
19MP0000762_abnormal_tongue_morphology2.43766838
20MP0002098_abnormal_vibrissa_morphology2.35641716
21MP0002254_reproductive_system_inflammat2.27472135
22MP0004381_abnormal_hair_follicle2.20932363
23MP0000377_abnormal_hair_follicle2.16977752
24MP0001188_hyperpigmentation2.11782816
25MP0000647_abnormal_sebaceous_gland1.87016965
26MP0003191_abnormal_cellular_cholesterol1.82371979
27MP0001849_ear_inflammation1.75871531
28MP0000427_abnormal_hair_cycle1.75250872
29MP0009053_abnormal_anal_canal1.74383595
30MP0000566_synostosis1.72040826
31MP0009931_abnormal_skin_appearance1.64810753
32MP0001191_abnormal_skin_condition1.50668757
33MP0000465_gastrointestinal_hemorrhage1.49220442
34MP0002234_abnormal_pharynx_morphology1.48406549
35MP0000537_abnormal_urethra_morphology1.48104153
36MP0008438_abnormal_cutaneous_collagen1.44148801
37MP0005023_abnormal_wound_healing1.41181002
38MP0004185_abnormal_adipocyte_glucose1.37407019
39MP0010352_gastrointestinal_tract_polyps1.36033728
40MP0004264_abnormal_extraembryonic_tissu1.31871397
41MP0006054_spinal_hemorrhage1.24102165
42MP0009379_abnormal_foot_pigmentation1.24034344
43MP0005451_abnormal_body_composition1.21944148
44MP0001851_eye_inflammation1.19031608
45MP0001243_abnormal_dermal_layer1.16200573
46MP0003436_decreased_susceptibility_to1.13265852
47MP0004272_abnormal_basement_membrane1.12517838
48MP0003303_peritoneal_inflammation1.12395372
49MP0000367_abnormal_coat/_hair1.10742843
50MP0002095_abnormal_skin_pigmentation1.00434006
51MP0005409_darkened_coat_color0.96468991
52MP0004858_abnormal_nervous_system0.94677783
53MP0003300_gastrointestinal_ulcer0.92809921
54MP0008004_abnormal_stomach_pH0.87245415
55MP0004782_abnormal_surfactant_physiolog0.84299816
56MP0000627_abnormal_mammary_gland0.84096110
57MP0004885_abnormal_endolymph0.80418174
58MP0002282_abnormal_trachea_morphology0.76947483
59MP0001340_abnormal_eyelid_morphology0.72332061
60MP0005083_abnormal_biliary_tract0.71719739
61MP0004019_abnormal_vitamin_homeostasis0.71142439
62MP0002877_abnormal_melanocyte_morpholog0.69417958
63MP0003045_fibrosis0.68817778
64MP0005076_abnormal_cell_differentiation0.67685148
65MP0001346_abnormal_lacrimal_gland0.65391169
66MP0005248_abnormal_Harderian_gland0.65017651
67MP0003755_abnormal_palate_morphology0.64814591
68MP0003075_altered_response_to0.62237984
69MP0003950_abnormal_plasma_membrane0.60624534
70MP0002138_abnormal_hepatobiliary_system0.59871541
71MP0001533_abnormal_skeleton_physiology0.58840990
72MP0003329_amyloid_beta_deposits0.58145520
73MP0001784_abnormal_fluid_regulation0.57791172
74MP0001881_abnormal_mammary_gland0.54995371
75MP0001666_abnormal_nutrient_absorption0.54694339
76MP0003315_abnormal_perineum_morphology0.53186527
77MP0005508_abnormal_skeleton_morphology0.52873647
78MP0009785_altered_susceptibility_to0.52575979
79MP0004043_abnormal_pH_regulation0.51090873
80MP0008789_abnormal_olfactory_epithelium0.49829808
81MP0002909_abnormal_adrenal_gland0.48867300
82MP0002177_abnormal_outer_ear0.48705258
83MP0010368_abnormal_lymphatic_system0.48689938
84MP0010155_abnormal_intestine_physiology0.47859586
85MP0010030_abnormal_orbit_morphology0.47706831
86MP0003011_delayed_dark_adaptation0.47388993
87MP0009764_decreased_sensitivity_to0.47163560
88MP0005390_skeleton_phenotype0.46575010
89MP0001958_emphysema0.45025676
90MP0001765_abnormal_ion_homeostasis0.44592363
91MP0001485_abnormal_pinna_reflex0.44587634
92MP0000343_altered_response_to0.44550961
93MP0005503_abnormal_tendon_morphology0.41701826
94MP0002111_abnormal_tail_morphology0.40989536
95MP0003448_altered_tumor_morphology0.39891170
96MP0000604_amyloidosis0.38460666
97MP0002896_abnormal_bone_mineralization0.38237458
98MP0005166_decreased_susceptibility_to0.37712267
99MP0000750_abnormal_muscle_regeneration0.36738101
100MP0005623_abnormal_meninges_morphology0.35978374
101MP0001177_atelectasis0.35910512
102MP0004197_abnormal_fetal_growth/weight/0.34599689
103MP0005193_abnormal_anterior_eye0.34379140
104MP0000538_abnormal_urinary_bladder0.33290813
105MP0002233_abnormal_nose_morphology0.32807799
106MP0005666_abnormal_adipose_tissue0.32743938
107MP0005025_abnormal_response_to0.32185582
108MP0000477_abnormal_intestine_morphology0.32028522
109MP0005375_adipose_tissue_phenotype0.31228734
110MP0000733_abnormal_muscle_development0.31079833
111MP0000432_abnormal_head_morphology0.30032287
112MP0002133_abnormal_respiratory_system0.28580868
113MP0005388_respiratory_system_phenotype0.28580868
114MP0003763_abnormal_thymus_physiology0.26200813
115MP0000015_abnormal_ear_pigmentation0.26114014
116MP0005075_abnormal_melanosome_morpholog0.25392330
117MP0005174_abnormal_tail_pigmentation0.24618093
118MP0009333_abnormal_splenocyte_physiolog0.22049752
119MP0000003_abnormal_adipose_tissue0.20473738
120MP0009672_abnormal_birth_weight0.19695600
121MP0003638_abnormal_response/metabolism_0.18049143
122MP0008260_abnormal_autophagy0.17733162
123MP0003828_pulmonary_edema0.16280532
124MP0000685_abnormal_immune_system0.15895621
125MP0003221_abnormal_cardiomyocyte_apopto0.14910822
126MP0002009_preneoplasia0.13829532
127MP0005394_taste/olfaction_phenotype0.13575195
128MP0005499_abnormal_olfactory_system0.13575195
129MP0001186_pigmentation_phenotype0.13028425
130MP0001502_abnormal_circadian_rhythm0.11834822
131MP0000470_abnormal_stomach_morphology0.09666945
132MP0002697_abnormal_eye_size0.09470046
133MP0008569_lethality_at_weaning0.08561054
134MP0009840_abnormal_foam_cell0.07684311
135MP0000428_abnormal_craniofacial_morphol0.06068737
136MP0009765_abnormal_xenobiotic_induced0.05268214
137MP0001299_abnormal_eye_distance/0.04776165

Predicted human phenotypes

RankGene SetZ-score
1Onycholysis (HP:0001806)7.45173492
2Fragile nails (HP:0001808)7.22424892
3Thick nail (HP:0001805)7.16758579
4Plantar hyperkeratosis (HP:0007556)7.16682543
5Milia (HP:0001056)5.99978019
6Palmoplantar hyperkeratosis (HP:0000972)5.91896312
7Alopecia of scalp (HP:0002293)5.87830319
8Congenital ichthyosiform erythroderma (HP:0007431)5.83551125
9Right ventricular cardiomyopathy (HP:0011663)5.59388958
10Palmar hyperkeratosis (HP:0010765)5.55312265
11Abnormality of secondary sexual hair (HP:0009888)5.10137928
12Abnormality of the axillary hair (HP:0100134)5.10137928
13Oral leukoplakia (HP:0002745)5.05185333
14Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.01646375
15Woolly hair (HP:0002224)5.01312621
16Abnormal blistering of the skin (HP:0008066)4.99414384
17Hypotrichosis (HP:0001006)4.77691169
18Atrophic scars (HP:0001075)4.34019520
19Follicular hyperkeratosis (HP:0007502)4.28983154
20Lip pit (HP:0100267)4.15439717
21Pili torti (HP:0003777)4.11907658
22Increased IgE level (HP:0003212)4.08603274
23Nail dystrophy (HP:0008404)4.05022061
24Erythema (HP:0010783)3.84593437
25Ectropion (HP:0000656)3.72565813
26Corneal erosion (HP:0200020)3.55985071
27Erythroderma (HP:0001019)3.49503177
28Ridged nail (HP:0001807)3.35397851
29Gangrene (HP:0100758)3.22284653
30Palmoplantar keratoderma (HP:0000982)3.19808518
31Hypohidrosis (HP:0000966)3.11881660
32Absent hair (HP:0002298)3.10842493
33Laryngomalacia (HP:0001601)3.03696859
34Furrowed tongue (HP:0000221)3.01241491
35Curly hair (HP:0002212)2.77298087
36Abnormality of placental membranes (HP:0011409)2.76143147
37Amniotic constriction ring (HP:0009775)2.76143147
38Parakeratosis (HP:0001036)2.75717081
39Corneal dystrophy (HP:0001131)2.74151009
40Pustule (HP:0200039)2.73370964
41Sparse scalp hair (HP:0002209)2.73270105
42Abnormal hair laboratory examination (HP:0003328)2.68820954
43Pruritus (HP:0000989)2.66766322
44Anonychia (HP:0001798)2.59463990
45Abnormality of the neuromuscular junction (HP:0003398)2.58485019
46Fatigable weakness (HP:0003473)2.58485019
47Hamartoma of the eye (HP:0010568)2.57072304
48Ventricular tachycardia (HP:0004756)2.52471772
49Hypergammaglobulinemia (HP:0010702)2.41739701
50Hyporeflexia of lower limbs (HP:0002600)2.39480307
51Autoamputation (HP:0001218)2.38721916
52Lack of skin elasticity (HP:0100679)2.37412878
53Distal lower limb muscle weakness (HP:0009053)2.35600015
54Abnormality of the distal phalanges of the toes (HP:0010182)2.27367401
55Fragile skin (HP:0001030)2.27312994
56Abnormality of the salivary glands (HP:0010286)2.26002180
57Hyperhidrosis (HP:0000975)2.25875242
58Conjunctival hamartoma (HP:0100780)2.25799457
59Advanced eruption of teeth (HP:0006288)2.22676565
60Muscle fiber splitting (HP:0003555)2.20596169
61Pterygium (HP:0001059)2.16580022
62Premature rupture of membranes (HP:0001788)2.15078119
63Natal tooth (HP:0000695)2.11313301
64Popliteal pterygium (HP:0009756)2.10479004
65Urticaria (HP:0001025)2.07236015
66Multifactorial inheritance (HP:0001426)2.06294749
67Dehydration (HP:0001944)2.01898267
68Amyloidosis (HP:0011034)2.00012298
69Abnormality of nail color (HP:0100643)10.4035963
70Brittle hair (HP:0002299)1.98947903
71Increased connective tissue (HP:0009025)1.97145765
72Hypoplasia of dental enamel (HP:0006297)1.94972549
73Peritonitis (HP:0002586)1.92387895
74Sparse eyelashes (HP:0000653)1.89884021
75Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.87625388
76Paralysis (HP:0003470)1.87475597
77Type 1 muscle fiber predominance (HP:0003803)1.86300358
78Carious teeth (HP:0000670)1.86135326
79Recurrent corneal erosions (HP:0000495)1.85030166
80Hypoplastic labia majora (HP:0000059)1.81590204
81Blepharitis (HP:0000498)1.81140614
82Achilles tendon contracture (HP:0001771)1.80016274
83Abnormality of the fingernails (HP:0001231)1.78394543
84Muscle fiber inclusion bodies (HP:0100299)1.76983951
85Round ear (HP:0100830)1.72678749
86Melanocytic nevus (HP:0000995)1.72310575
87Skin ulcer (HP:0200042)1.70717709
88Dry skin (HP:0000958)1.70325566
89Keratoconjunctivitis sicca (HP:0001097)1.67293621
90Abnormality of the Achilles tendon (HP:0005109)1.66495040
91Nemaline bodies (HP:0003798)1.66390475
92Eczematoid dermatitis (HP:0000976)1.65680127
93Slow-growing hair (HP:0002217)1.64549717
94Abnormality of hair growth rate (HP:0011363)1.64549717
95Acanthosis nigricans (HP:0000956)1.64362287
96Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.63758565
97Humeroradial synostosis (HP:0003041)1.63577476
98Synostosis involving the elbow (HP:0003938)1.63577476
99Down-sloping shoulders (HP:0200021)1.63282988
100Selective tooth agenesis (HP:0001592)1.62361688
101Trismus (HP:0000211)1.61540441
102Abnormality of the labia majora (HP:0012881)1.60432934
103Abnormality of the gastric mucosa (HP:0004295)1.59593368
104Papilloma (HP:0012740)1.59338088
105Verrucae (HP:0200043)1.59338088
106Distal arthrogryposis (HP:0005684)1.57031317
107Absent eyelashes (HP:0000561)1.56481997
108Vascular calcification (HP:0004934)1.56268929
109Esophageal atresia (HP:0002032)1.52127353
110Keratoconjunctivitis (HP:0001096)1.51360512
111Neck muscle weakness (HP:0000467)1.51314772
112Hypodontia (HP:0000668)1.50430013
113Labial hypoplasia (HP:0000066)1.49658052
114Bronchomalacia (HP:0002780)1.49596768
115Cardiovascular calcification (HP:0011915)1.49192749
116Axonal loss (HP:0003447)1.47738882
117Depressed nasal tip (HP:0000437)1.45798913
118Protrusio acetabuli (HP:0003179)1.45762855
119Mildly elevated creatine phosphokinase (HP:0008180)1.43657017
120Hypoplastic toenails (HP:0001800)1.43014409
121Interstitial pulmonary disease (HP:0006530)1.41947924
122Myopathic facies (HP:0002058)1.41869247
123Limb-girdle muscle atrophy (HP:0003797)1.41641147
124Fine hair (HP:0002213)1.41380873
125Hyperparathyroidism (HP:0000843)1.38712186
126Cerebral aneurysm (HP:0004944)1.38329234
127Hamartoma (HP:0010566)1.37947145
128Sepsis (HP:0100806)1.37905443
129Duplicated collecting system (HP:0000081)1.37278617
130Recurrent bacterial skin infections (HP:0005406)1.36665507
131Split foot (HP:0001839)1.35634733
132Xerostomia (HP:0000217)1.33927704
133Dry hair (HP:0011359)1.32855589
134Segmental peripheral demyelination/remyelination (HP:0003481)1.28777747
135Everted lower lip vermilion (HP:0000232)1.27764796
136Preauricular skin tag (HP:0000384)1.27529105
137Septate vagina (HP:0001153)1.23754475
138Generalized hyperpigmentation (HP:0007440)1.21365762
139Conical tooth (HP:0000698)1.20840862
140Skin tags (HP:0010609)1.17746389

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA27.86514898
2ERN13.93220032
3EPHB23.81789435
4MST43.43352960
5FER3.40803049
6MAP3K33.11342002
7MST1R2.97645877
8SGK2232.79705909
9SGK4942.79705909
10MAPKAPK32.44918067
11MAP3K22.26345293
12IRAK12.10601140
13TRIB32.05200531
14EPHB11.71925812
15TRPM71.70249643
16RIPK11.69012345
17RPS6KB21.67435440
18PTK61.61885945
19TESK11.59397255
20LRRK21.57917058
21PKN21.55996248
22BLK1.52415264
23GRK61.46141816
24ERBB31.44493973
25TGFBR21.38528336
26PTK21.37798501
27STK38L1.35072557
28IKBKB1.33255224
29FRK1.31985581
30NME11.31760327
31LATS11.30951175
32RPS6KA41.25287398
33MAP3K91.23899626
34IRAK21.19127250
35WNK11.18179111
36PIK3CG1.17832875
37BMX1.14998182
38STK101.14352215
39TTN1.14317256
40LIMK11.09788652
41TAOK11.07172358
42IRAK41.05265039
43IKBKE1.04826436
44MET1.04197430
45PIM21.03985455
46ABL21.03256322
47MAPK71.00683040
48FGFR40.99163666
49MAP2K60.98641619
50IRAK30.98161918
51DDR20.97572199
52EPHA30.95526268
53MAP2K30.94038428
54TYK20.93770305
55MAP3K60.92822315
56PRPF4B0.89890540
57CDK120.89324860
58MAP3K10.87619138
59MAP3K110.86972754
60EEF2K0.82081858
61FGFR10.79605467
62MARK20.79389799
63MAP3K120.78700701
64MAP2K10.77006814
65MATK0.76137922
66FGFR30.75395905
67PDGFRA0.72517730
68STK380.72509930
69NLK0.71903400
70SGK20.70740172
71CSK0.67802492
72JAK30.66396909
73DMPK0.66101330
74TBK10.65440280
75ILK0.65193377
76SGK30.64151579
77FGR0.63780994
78STK240.62379703
79PAK40.62062740
80LATS20.60120814
81SGK10.59449802
82LMTK20.58502988
83ROCK20.58223933
84AKT30.55809685
85ERBB20.55591811
86MTOR0.54229733
87BCR0.54150898
88DYRK30.53925620
89MAPKAPK50.53450235
90RPS6KB10.50202299
91PDGFRB0.49926136
92CDK60.49769066
93SRC0.49755642
94PRKCI0.49301345
95PAK30.48424627
96MAPKAPK20.45913626
97MAP2K20.44993965
98FGFR20.44278376
99EGFR0.42117013
100KSR20.41754351
101MAP3K140.41314651
102PKN10.39960888
103KIT0.38187470
104MAPK120.37797771
105MOS0.36846965
106TYRO30.36489951
107PRKD10.36094775
108PRKCE0.35731581
109MAP2K40.35069915
110JAK10.34703094
111MAPK40.34629559
112ZAP700.33837866
113CDC42BPA0.33605900
114TAOK30.33423341
115SIK30.32941540
116ERBB40.32536640
117HCK0.32156370
118MAPK150.32148449
119PRKD20.31898244
120TGFBR10.31234508
121TAOK20.30128200
122PAK20.29998651
123FES0.29609469
124MAP3K70.28634213
125ROCK10.28584694
126PIK3CA0.27827789
127FYN0.27788376
128JAK20.27481568
129HIPK20.27414995
130GSK3A0.26583419
131PBK0.25051352
132MAP3K100.24897458
133RPS6KA10.24806990
134PRKAA20.24465286
135RET0.23076645
136ABL10.21156821
137MAP3K50.19883318
138ADRBK10.19446056
139STK30.19274150
140NTRK10.18137180

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.80900204
2Arachidonic acid metabolism_Homo sapiens_hsa005902.51211595
3Linoleic acid metabolism_Homo sapiens_hsa005912.47172987
4alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.40695262
5ECM-receptor interaction_Homo sapiens_hsa045122.34604881
6Cyanoamino acid metabolism_Homo sapiens_hsa004602.30964228
7Ovarian steroidogenesis_Homo sapiens_hsa049132.29908615
8Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.21804533
9Long-term depression_Homo sapiens_hsa047301.93227684
10Amoebiasis_Homo sapiens_hsa051461.91057695
11Staphylococcus aureus infection_Homo sapiens_hsa051501.86402852
12Mineral absorption_Homo sapiens_hsa049781.84114957
13Adherens junction_Homo sapiens_hsa045201.74533477
14Tight junction_Homo sapiens_hsa045301.74226459
15Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.69368776
16Glycerophospholipid metabolism_Homo sapiens_hsa005641.69212823
17Toxoplasmosis_Homo sapiens_hsa051451.66960011
18Histidine metabolism_Homo sapiens_hsa003401.66306800
19Proteoglycans in cancer_Homo sapiens_hsa052051.65047586
20Leukocyte transendothelial migration_Homo sapiens_hsa046701.63915442
21Bladder cancer_Homo sapiens_hsa052191.59693367
22Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.59093298
23Pertussis_Homo sapiens_hsa051331.52586562
24Serotonergic synapse_Homo sapiens_hsa047261.48085662
25Phenylalanine metabolism_Homo sapiens_hsa003601.45668770
26Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.45203328
27Ether lipid metabolism_Homo sapiens_hsa005651.43669013
28Sphingolipid metabolism_Homo sapiens_hsa006001.41090530
29Circadian rhythm_Homo sapiens_hsa047101.40902057
30Small cell lung cancer_Homo sapiens_hsa052221.38236698
31Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.37489738
32Chemical carcinogenesis_Homo sapiens_hsa052041.35503023
33VEGF signaling pathway_Homo sapiens_hsa043701.33532433
34Choline metabolism in cancer_Homo sapiens_hsa052311.32224733
35Fat digestion and absorption_Homo sapiens_hsa049751.29356905
36Focal adhesion_Homo sapiens_hsa045101.29287119
37Salmonella infection_Homo sapiens_hsa051321.24030618
38Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.17065105
39Leishmaniasis_Homo sapiens_hsa051401.16382929
40Caffeine metabolism_Homo sapiens_hsa002321.15533497
41TNF signaling pathway_Homo sapiens_hsa046681.07390549
42Salivary secretion_Homo sapiens_hsa049701.07210927
43Glutathione metabolism_Homo sapiens_hsa004801.05866666
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.04414820
45Hippo signaling pathway_Homo sapiens_hsa043901.03346570
46Complement and coagulation cascades_Homo sapiens_hsa046100.99034050
47Hepatitis C_Homo sapiens_hsa051600.97892594
48Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.96188465
49GnRH signaling pathway_Homo sapiens_hsa049120.96027246
50Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.95713993
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.95153458
52Malaria_Homo sapiens_hsa051440.92746431
53Shigellosis_Homo sapiens_hsa051310.92370228
54Vibrio cholerae infection_Homo sapiens_hsa051100.91988966
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.91255356
56Axon guidance_Homo sapiens_hsa043600.90778676
57Pancreatic secretion_Homo sapiens_hsa049720.90266177
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.89854229
59Platelet activation_Homo sapiens_hsa046110.88789322
60Phototransduction_Homo sapiens_hsa047440.86978596
61Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.86885780
62Fatty acid elongation_Homo sapiens_hsa000620.85729169
63Legionellosis_Homo sapiens_hsa051340.83948835
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.83785946
65Dilated cardiomyopathy_Homo sapiens_hsa054140.80573579
66Regulation of actin cytoskeleton_Homo sapiens_hsa048100.79946099
67Tuberculosis_Homo sapiens_hsa051520.77806958
68Glutamatergic synapse_Homo sapiens_hsa047240.76395672
69Renal cell carcinoma_Homo sapiens_hsa052110.74682227
70HIF-1 signaling pathway_Homo sapiens_hsa040660.74584392
71Basal cell carcinoma_Homo sapiens_hsa052170.72889229
72Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.72610521
73Gastric acid secretion_Homo sapiens_hsa049710.71985247
74Osteoclast differentiation_Homo sapiens_hsa043800.71563455
75ABC transporters_Homo sapiens_hsa020100.70759018
76Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.69831907
77Oxytocin signaling pathway_Homo sapiens_hsa049210.69562306
78Thyroid cancer_Homo sapiens_hsa052160.68801613
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.67300802
80Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.67276973
81Retinol metabolism_Homo sapiens_hsa008300.66254840
82Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65735236
83Thyroid hormone synthesis_Homo sapiens_hsa049180.65117660
84Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.61017621
85MAPK signaling pathway_Homo sapiens_hsa040100.60839773
86p53 signaling pathway_Homo sapiens_hsa041150.59859689
87Apoptosis_Homo sapiens_hsa042100.59739015
88Jak-STAT signaling pathway_Homo sapiens_hsa046300.59456154
89Endocytosis_Homo sapiens_hsa041440.59041509
90Dorso-ventral axis formation_Homo sapiens_hsa043200.58013369
91MicroRNAs in cancer_Homo sapiens_hsa052060.57909880
92Central carbon metabolism in cancer_Homo sapiens_hsa052300.56489567
93Acute myeloid leukemia_Homo sapiens_hsa052210.56133786
94Arginine biosynthesis_Homo sapiens_hsa002200.56044711
95Melanogenesis_Homo sapiens_hsa049160.56043784
96Pathways in cancer_Homo sapiens_hsa052000.54196249
97Influenza A_Homo sapiens_hsa051640.54139777
98Rap1 signaling pathway_Homo sapiens_hsa040150.52387106
99NOD-like receptor signaling pathway_Homo sapiens_hsa046210.51296130
100Phagosome_Homo sapiens_hsa041450.51052879
101RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.51037399
102Ribosome_Homo sapiens_hsa030100.50336062
103Renin secretion_Homo sapiens_hsa049240.49875615
104Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.49826432
105Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.48738373
106Bile secretion_Homo sapiens_hsa049760.48493497
107Estrogen signaling pathway_Homo sapiens_hsa049150.48490403
108Hematopoietic cell lineage_Homo sapiens_hsa046400.47383308
109Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47239812
110Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.47189319
111Vascular smooth muscle contraction_Homo sapiens_hsa042700.46690667
112Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45850949
113Chronic myeloid leukemia_Homo sapiens_hsa052200.45482752
114Ras signaling pathway_Homo sapiens_hsa040140.45446069
115Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.44595261
116Protein digestion and absorption_Homo sapiens_hsa049740.44546748
117Glioma_Homo sapiens_hsa052140.42586239
118Neurotrophin signaling pathway_Homo sapiens_hsa047220.38748527
119Inositol phosphate metabolism_Homo sapiens_hsa005620.37742678
120ErbB signaling pathway_Homo sapiens_hsa040120.36033732
121Steroid hormone biosynthesis_Homo sapiens_hsa001400.34509684
122Fructose and mannose metabolism_Homo sapiens_hsa000510.31521709
123Long-term potentiation_Homo sapiens_hsa047200.30546915
124Collecting duct acid secretion_Homo sapiens_hsa049660.29968866
125PPAR signaling pathway_Homo sapiens_hsa033200.28844080
126Hedgehog signaling pathway_Homo sapiens_hsa043400.28646277
127Insulin signaling pathway_Homo sapiens_hsa049100.27071662
128Galactose metabolism_Homo sapiens_hsa000520.24151427
129Pancreatic cancer_Homo sapiens_hsa052120.19129707
130Renin-angiotensin system_Homo sapiens_hsa046140.16830269
131cAMP signaling pathway_Homo sapiens_hsa040240.16662762
132FoxO signaling pathway_Homo sapiens_hsa040680.13276641

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