Rank | Gene Set | Z-score |
---|---|---|
1 | pre-miRNA processing (GO:0031054) | 4.19693847 |
2 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 4.11552331 |
3 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.11281291 |
4 | positive regulation of histone deacetylation (GO:0031065) | 3.95478968 |
5 | regulation of translational fidelity (GO:0006450) | 3.75280701 |
6 | layer formation in cerebral cortex (GO:0021819) | 3.68297095 |
7 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.48491390 |
8 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.45355785 |
9 | cellular potassium ion homeostasis (GO:0030007) | 3.42080323 |
10 | Golgi transport vesicle coating (GO:0048200) | 3.40625440 |
11 | COPI coating of Golgi vesicle (GO:0048205) | 3.40625440 |
12 | peptidyl-lysine dimethylation (GO:0018027) | 3.38811483 |
13 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.37097421 |
14 | heterochromatin organization (GO:0070828) | 3.34428297 |
15 | positive regulation of synapse maturation (GO:0090129) | 3.32515393 |
16 | protein retention in ER lumen (GO:0006621) | 3.30350919 |
17 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.28367215 |
18 | glutamate secretion (GO:0014047) | 3.27439563 |
19 | cell communication by electrical coupling (GO:0010644) | 3.24952012 |
20 | cerebellar granule cell differentiation (GO:0021707) | 3.24360632 |
21 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.23612816 |
22 | cell-cell junction maintenance (GO:0045217) | 3.21531397 |
23 | polarized epithelial cell differentiation (GO:0030859) | 3.18556053 |
24 | sodium ion export (GO:0071436) | 3.17334902 |
25 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.14465273 |
26 | regulation of translational termination (GO:0006449) | 3.13856810 |
27 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.10711677 |
28 | neuromuscular process controlling balance (GO:0050885) | 3.08787474 |
29 | negative regulation of cell size (GO:0045792) | 3.07614650 |
30 | DNA unwinding involved in DNA replication (GO:0006268) | 3.07435779 |
31 | locomotory exploration behavior (GO:0035641) | 3.06492996 |
32 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.02883819 |
33 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.01188445 |
34 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.98119780 |
35 | glial cell proliferation (GO:0014009) | 2.96713479 |
36 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.90614617 |
37 | regulation of ARF GTPase activity (GO:0032312) | 2.90377754 |
38 | amino acid import (GO:0043090) | 2.89538517 |
39 | adherens junction assembly (GO:0034333) | 2.89484285 |
40 | protein localization to endosome (GO:0036010) | 2.89305259 |
41 | activation of Rac GTPase activity (GO:0032863) | 2.88703582 |
42 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.88358287 |
43 | activation of MAPKKK activity (GO:0000185) | 2.87854913 |
44 | apoptotic process involved in morphogenesis (GO:0060561) | 2.86917303 |
45 | synaptic vesicle maturation (GO:0016188) | 2.84484394 |
46 | regulation of hippo signaling (GO:0035330) | 2.84186927 |
47 | negative regulation of histone methylation (GO:0031061) | 2.83999506 |
48 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.82933789 |
49 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.82681225 |
50 | mating behavior (GO:0007617) | 2.80690057 |
51 | negative regulation of fatty acid transport (GO:2000192) | 2.78541543 |
52 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.78264322 |
53 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.77554529 |
54 | proline biosynthetic process (GO:0006561) | 2.76673341 |
55 | regulation of early endosome to late endosome transport (GO:2000641) | 2.76453963 |
56 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.75920692 |
57 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.75785333 |
58 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.75465997 |
59 | mitochondrion transport along microtubule (GO:0047497) | 2.75465997 |
60 | NLS-bearing protein import into nucleus (GO:0006607) | 2.73586986 |
61 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.73489644 |
62 | synaptic vesicle exocytosis (GO:0016079) | 2.73342413 |
63 | convergent extension (GO:0060026) | 2.72002932 |
64 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.70000692 |
65 | positive regulation of RNA splicing (GO:0033120) | 2.68589652 |
66 | regulation of RNA export from nucleus (GO:0046831) | 2.67654627 |
67 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.67158722 |
68 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.66898580 |
69 | corticosteroid receptor signaling pathway (GO:0031958) | 2.66116725 |
70 | apical protein localization (GO:0045176) | 2.66073353 |
71 | positive regulation of protein deacetylation (GO:0090312) | 2.64283355 |
72 | establishment of mitochondrion localization (GO:0051654) | 2.63868580 |
73 | cell migration in hindbrain (GO:0021535) | 2.62779287 |
74 | dopamine receptor signaling pathway (GO:0007212) | 2.62240728 |
75 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.61745808 |
76 | cortical actin cytoskeleton organization (GO:0030866) | 2.61180828 |
77 | establishment of apical/basal cell polarity (GO:0035089) | 2.60778313 |
78 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.60690056 |
79 | peptidyl-arginine N-methylation (GO:0035246) | 2.59066121 |
80 | peptidyl-arginine methylation (GO:0018216) | 2.59066121 |
81 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.58908194 |
82 | receptor catabolic process (GO:0032801) | 2.55949618 |
83 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.55484041 |
84 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.55331468 |
85 | cerebellar Purkinje cell layer development (GO:0021680) | 2.54329366 |
86 | semaphorin-plexin signaling pathway (GO:0071526) | 2.54226050 |
87 | stress fiber assembly (GO:0043149) | 2.53137254 |
88 | neuronal ion channel clustering (GO:0045161) | 2.51847370 |
89 | maternal placenta development (GO:0001893) | 2.51444971 |
90 | establishment of nucleus localization (GO:0040023) | 2.49826529 |
91 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.49594585 |
92 | mRNA stabilization (GO:0048255) | 2.48523036 |
93 | RNA stabilization (GO:0043489) | 2.48523036 |
94 | protein targeting to plasma membrane (GO:0072661) | 2.47933780 |
95 | L-amino acid import (GO:0043092) | 2.46480937 |
96 | cell junction maintenance (GO:0034331) | 2.46327031 |
97 | negative regulation of microtubule polymerization (GO:0031115) | 2.44474520 |
98 | vocalization behavior (GO:0071625) | 2.44358149 |
99 | regulation of establishment of planar polarity (GO:0090175) | 2.44055832 |
100 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.42924726 |
101 | cellular sodium ion homeostasis (GO:0006883) | 2.41941820 |
102 | glucose 6-phosphate metabolic process (GO:0051156) | 2.41660032 |
103 | regulation of synaptic vesicle transport (GO:1902803) | 2.40796691 |
104 | dosage compensation (GO:0007549) | 2.40184240 |
105 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.39870043 |
106 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.39787125 |
107 | regulation of ARF protein signal transduction (GO:0032012) | 2.39712216 |
108 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling | 2.39259560 |
109 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.39259560 |
110 | signal complex assembly (GO:0007172) | 2.38925335 |
111 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.38770004 |
112 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.38770004 |
113 | neurotransmitter secretion (GO:0007269) | 2.38537002 |
114 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.38043711 |
115 | establishment of monopolar cell polarity (GO:0061162) | 2.37238184 |
116 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.37238184 |
117 | epithelial cell-cell adhesion (GO:0090136) | 2.37122967 |
118 | mitotic chromosome condensation (GO:0007076) | 2.37088843 |
119 | thymic T cell selection (GO:0045061) | 2.37072017 |
120 | activation of JUN kinase activity (GO:0007257) | 2.36380369 |
121 | hippo signaling (GO:0035329) | 2.35965037 |
122 | stress granule assembly (GO:0034063) | 2.35377523 |
123 | regulation of histone H3-K27 methylation (GO:0061085) | 2.35297305 |
124 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.34607023 |
125 | camera-type eye morphogenesis (GO:0048593) | 2.34175911 |
126 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.33690405 |
127 | regulation of chromatin binding (GO:0035561) | 2.33575900 |
128 | neural tube development (GO:0021915) | 2.33467238 |
129 | cell-substrate adherens junction assembly (GO:0007045) | 2.31929087 |
130 | focal adhesion assembly (GO:0048041) | 2.31929087 |
131 | labyrinthine layer blood vessel development (GO:0060716) | 2.31382784 |
132 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.29782501 |
133 | negative regulation of RNA splicing (GO:0033119) | 2.28927144 |
134 | protein-DNA complex disassembly (GO:0032986) | 2.27775595 |
135 | nucleosome disassembly (GO:0006337) | 2.27775595 |
136 | clathrin coat assembly (GO:0048268) | 2.26360074 |
137 | positive thymic T cell selection (GO:0045059) | 2.26032510 |
138 | response to nerve growth factor (GO:1990089) | 2.24957161 |
139 | cellular response to nerve growth factor stimulus (GO:1990090) | 2.24957161 |
140 | lens fiber cell development (GO:0070307) | 2.24940663 |
141 | cell-substrate junction assembly (GO:0007044) | 2.22151597 |
142 | response to epidermal growth factor (GO:0070849) | 2.20743838 |
143 | natural killer cell differentiation (GO:0001779) | 2.20674078 |
144 | negative regulation of cell killing (GO:0031342) | 2.20481448 |
145 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.20481448 |
146 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.20379134 |
147 | negative regulation of nucleotide catabolic process (GO:0030812) | 2.20265164 |
148 | L-serine transport (GO:0015825) | 2.19526509 |
149 | negative regulation of GTPase activity (GO:0034260) | 2.19072755 |
150 | negative regulation of GTP catabolic process (GO:0033125) | 2.19072755 |
151 | negative regulation of catenin import into nucleus (GO:0035414) | 2.18792717 |
152 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.18692197 |
153 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.18062522 |
154 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.17342327 |
155 | negative regulation of mRNA metabolic process (GO:1903312) | 2.17038025 |
156 | apoptotic process involved in development (GO:1902742) | 2.16958784 |
157 | positive regulation of dendrite morphogenesis (GO:0050775) | 2.16915439 |
158 | regulation of gene silencing by RNA (GO:0060966) | 2.16037073 |
159 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.16037073 |
160 | regulation of gene silencing by miRNA (GO:0060964) | 2.16037073 |
161 | actin filament bundle organization (GO:0061572) | 2.14785692 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MYC_22102868_ChIP-Seq_BL_Human | 3.87259450 |
2 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.71387571 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.69610761 |
4 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.89239031 |
5 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.85764893 |
6 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.85398389 |
7 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.84565044 |
8 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.83825395 |
9 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.82269278 |
10 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.62888354 |
11 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.60404720 |
12 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.58095769 |
13 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.56586048 |
14 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.53613710 |
15 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.49906858 |
16 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.28183673 |
17 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 2.23606168 |
18 | * LXR_22292898_ChIP-Seq_THP-1_Human | 2.17918534 |
19 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.16791318 |
20 | KDM2B_26808549_Chip-Seq_K562_Human | 2.11865729 |
21 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 2.10477546 |
22 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.09294842 |
23 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 2.04354871 |
24 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.83047757 |
25 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.80366043 |
26 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.77077848 |
27 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.77064725 |
28 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.74183546 |
29 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.73341331 |
30 | MAF_26560356_Chip-Seq_TH1_Human | 1.69705462 |
31 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.66443135 |
32 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.65636840 |
33 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.65290245 |
34 | UTX_26944678_Chip-Seq_JUKART_Human | 1.64087073 |
35 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.62490467 |
36 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.57653805 |
37 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.53292145 |
38 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.52702365 |
39 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.52585071 |
40 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.52127983 |
41 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.51193067 |
42 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.50139613 |
43 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.49963697 |
44 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.44830876 |
45 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.41407539 |
46 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.41094022 |
47 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.40482214 |
48 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.38328889 |
49 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.38108656 |
50 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.37843950 |
51 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.37538819 |
52 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.37156630 |
53 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.35132895 |
54 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.34772704 |
55 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.34727920 |
56 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.33295976 |
57 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.31645010 |
58 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.28029763 |
59 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.27872084 |
60 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.27856163 |
61 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.27203420 |
62 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.25822173 |
63 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.24498088 |
64 | P68_20966046_ChIP-Seq_HELA_Human | 1.23957282 |
65 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.23948606 |
66 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.22623695 |
67 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.22595973 |
68 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.22170917 |
69 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.21235356 |
70 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.18723931 |
71 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.17251464 |
72 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.16944052 |
73 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.16777399 |
74 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.16644241 |
75 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.16508119 |
76 | * OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.15921365 |
77 | * TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.14738912 |
78 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.14444473 |
79 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.13995734 |
80 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.13420167 |
81 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.13420167 |
82 | SPI1_23127762_ChIP-Seq_K562_Human | 1.12623196 |
83 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.12401671 |
84 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.11967510 |
85 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.11135038 |
86 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.10794037 |
87 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.10166697 |
88 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.09548356 |
89 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.09134071 |
90 | * MAF_26560356_Chip-Seq_TH2_Human | 1.07795428 |
91 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.07391820 |
92 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.07374377 |
93 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.07278918 |
94 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.06350714 |
95 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.06015786 |
96 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.06001828 |
97 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.05758775 |
98 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.05683568 |
99 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.05586945 |
100 | * FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.05124535 |
101 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.04957568 |
102 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.02893826 |
103 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.02362653 |
104 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.02304327 |
105 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.02169701 |
106 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.02026751 |
107 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.01487470 |
108 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.01293698 |
109 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.01233988 |
110 | GATA1_19941826_ChIP-Seq_K562_Human | 1.00004821 |
111 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.99592958 |
112 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.99272265 |
113 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.96580717 |
114 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.95936326 |
115 | * GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.95579812 |
116 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.94924498 |
117 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.93273397 |
118 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.92594994 |
119 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.92539116 |
120 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.92142972 |
121 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.91659992 |
122 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.91323484 |
123 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.91011794 |
124 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.90058116 |
125 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.89211854 |
126 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.89108155 |
127 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.87714085 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 3.87943531 |
2 | MP0000566_synostosis | 3.57448369 |
3 | MP0005076_abnormal_cell_differentiation | 3.30772060 |
4 | MP0010352_gastrointestinal_tract_polyps | 3.15508765 |
5 | MP0003300_gastrointestinal_ulcer | 3.01043596 |
6 | MP0004859_abnormal_synaptic_plasticity | 2.78062191 |
7 | MP0004858_abnormal_nervous_system | 2.77334010 |
8 | MP0005409_darkened_coat_color | 2.68425917 |
9 | MP0003303_peritoneal_inflammation | 2.65852422 |
10 | MP0010234_abnormal_vibrissa_follicle | 2.62774059 |
11 | MP0005423_abnormal_somatic_nervous | 2.44531513 |
12 | MP0009278_abnormal_bone_marrow | 2.41435258 |
13 | MP0008961_abnormal_basal_metabolism | 2.36418098 |
14 | MP0005623_abnormal_meninges_morphology | 2.29459642 |
15 | MP0003283_abnormal_digestive_organ | 2.25074077 |
16 | MP0000537_abnormal_urethra_morphology | 2.22020281 |
17 | MP0001849_ear_inflammation | 2.15314785 |
18 | MP0000579_abnormal_nail_morphology | 2.02655028 |
19 | MP0001348_abnormal_lacrimal_gland | 2.02648191 |
20 | MP0002653_abnormal_ependyma_morphology | 1.98755046 |
21 | MP0002089_abnormal_postnatal_growth/wei | 1.78783878 |
22 | MP0003566_abnormal_cell_adhesion | 1.77723811 |
23 | MP0002249_abnormal_larynx_morphology | 1.75523236 |
24 | MP0002877_abnormal_melanocyte_morpholog | 1.74235894 |
25 | MP0000733_abnormal_muscle_development | 1.71136687 |
26 | MP0003091_abnormal_cell_migration | 1.70558305 |
27 | MP0003329_amyloid_beta_deposits | 1.68398353 |
28 | MP0000678_abnormal_parathyroid_gland | 1.66852776 |
29 | MP0005451_abnormal_body_composition | 1.66771161 |
30 | MP0000569_abnormal_digit_pigmentation | 1.63831337 |
31 | MP0004197_abnormal_fetal_growth/weight/ | 1.61701327 |
32 | MP0002063_abnormal_learning/memory/cond | 1.54609858 |
33 | MP0004264_abnormal_extraembryonic_tissu | 1.52356412 |
34 | MP0010030_abnormal_orbit_morphology | 1.48741918 |
35 | MP0005257_abnormal_intraocular_pressure | 1.48049274 |
36 | MP0009780_abnormal_chondrocyte_physiolo | 1.47780541 |
37 | MP0002084_abnormal_developmental_patter | 1.46250020 |
38 | MP0001730_embryonic_growth_arrest | 1.45217854 |
39 | MP0003115_abnormal_respiratory_system | 1.42276029 |
40 | MP0002822_catalepsy | 1.41308000 |
41 | MP0003634_abnormal_glial_cell | 1.39078536 |
42 | MP0003119_abnormal_digestive_system | 1.34598695 |
43 | MP0000428_abnormal_craniofacial_morphol | 1.33141702 |
44 | MP0002234_abnormal_pharynx_morphology | 1.32855569 |
45 | MP0004808_abnormal_hematopoietic_stem | 1.32431885 |
46 | MP0004233_abnormal_muscle_weight | 1.31095369 |
47 | MP0000534_abnormal_ureter_morphology | 1.28906943 |
48 | MP0001346_abnormal_lacrimal_gland | 1.24128480 |
49 | MP0004885_abnormal_endolymph | 1.24086367 |
50 | MP0008770_decreased_survivor_rate | 1.22641103 |
51 | MP0000350_abnormal_cell_proliferation | 1.22628413 |
52 | MP0004947_skin_inflammation | 1.22619023 |
53 | MP0010307_abnormal_tumor_latency | 1.21469379 |
54 | MP0002085_abnormal_embryonic_tissue | 1.19132737 |
55 | MP0002064_seizures | 1.17781536 |
56 | MP0000685_abnormal_immune_system | 1.17652624 |
57 | MP0002796_impaired_skin_barrier | 1.17350663 |
58 | MP0005023_abnormal_wound_healing | 1.16145745 |
59 | MP0002734_abnormal_mechanical_nocicepti | 1.13467610 |
60 | MP0003861_abnormal_nervous_system | 1.12413600 |
61 | MP0002086_abnormal_extraembryonic_tissu | 1.10600139 |
62 | MP0004811_abnormal_neuron_physiology | 1.09145873 |
63 | MP0003045_fibrosis | 1.08017649 |
64 | MP0003123_paternal_imprinting | 1.07236181 |
65 | MP0000703_abnormal_thymus_morphology | 1.02189793 |
66 | MP0001697_abnormal_embryo_size | 1.01767406 |
67 | MP0002080_prenatal_lethality | 1.01182753 |
68 | MP0002925_abnormal_cardiovascular_devel | 1.00836526 |
69 | MP0002909_abnormal_adrenal_gland | 0.99697957 |
70 | MP0004272_abnormal_basement_membrane | 0.98800946 |
71 | MP0000751_myopathy | 0.98120004 |
72 | MP0005666_abnormal_adipose_tissue | 0.97456556 |
73 | MP0000462_abnormal_digestive_system | 0.97156228 |
74 | MP0000003_abnormal_adipose_tissue | 0.96920401 |
75 | MP0003172_abnormal_lysosome_physiology | 0.96341557 |
76 | MP0003942_abnormal_urinary_system | 0.96117973 |
77 | MP0003635_abnormal_synaptic_transmissio | 0.95668460 |
78 | MP0010630_abnormal_cardiac_muscle | 0.94841702 |
79 | MP0003880_abnormal_central_pattern | 0.94288202 |
80 | MP0001672_abnormal_embryogenesis/_devel | 0.93515622 |
81 | MP0005380_embryogenesis_phenotype | 0.93515622 |
82 | MP0001915_intracranial_hemorrhage | 0.92678116 |
83 | MP0002088_abnormal_embryonic_growth/wei | 0.92135255 |
84 | MP0002092_abnormal_eye_morphology | 0.92133685 |
85 | MP0003866_abnormal_defecation | 0.91561736 |
86 | MP0004510_myositis | 0.91199169 |
87 | MP0003279_aneurysm | 0.91155591 |
88 | MP0003984_embryonic_growth_retardation | 0.91054551 |
89 | MP0001958_emphysema | 0.90756690 |
90 | MP0000955_abnormal_spinal_cord | 0.90738632 |
91 | MP0002396_abnormal_hematopoietic_system | 0.90459586 |
92 | MP0008260_abnormal_autophagy | 0.89686255 |
93 | MP0009053_abnormal_anal_canal | 0.89642981 |
94 | MP0009840_abnormal_foam_cell | 0.89640834 |
95 | MP0004185_abnormal_adipocyte_glucose | 0.88532091 |
96 | MP0003453_abnormal_keratinocyte_physiol | 0.88338847 |
97 | MP0005501_abnormal_skin_physiology | 0.88101165 |
98 | MP0000604_amyloidosis | 0.87502454 |
99 | MP0004270_analgesia | 0.87168661 |
100 | MP0005058_abnormal_lysosome_morphology | 0.87084155 |
101 | MP0002009_preneoplasia | 0.86886280 |
102 | MP0005397_hematopoietic_system_phenotyp | 0.86750809 |
103 | MP0001545_abnormal_hematopoietic_system | 0.86750809 |
104 | MP0000778_abnormal_nervous_system | 0.86587691 |
105 | MP0002882_abnormal_neuron_morphology | 0.86001034 |
106 | MP0002697_abnormal_eye_size | 0.85896267 |
107 | MP0002572_abnormal_emotion/affect_behav | 0.85145288 |
108 | MP0006054_spinal_hemorrhage | 0.84258627 |
109 | MP0009672_abnormal_birth_weight | 0.84044254 |
110 | MP0002184_abnormal_innervation | 0.83568209 |
111 | MP0003111_abnormal_nucleus_morphology | 0.83545740 |
112 | MP0005499_abnormal_olfactory_system | 0.82137490 |
113 | MP0005394_taste/olfaction_phenotype | 0.82137490 |
114 | MP0002398_abnormal_bone_marrow | 0.81311630 |
115 | MP0010678_abnormal_skin_adnexa | 0.81137752 |
116 | MP0009703_decreased_birth_body | 0.80331765 |
117 | MP0002152_abnormal_brain_morphology | 0.80274458 |
118 | MP0000920_abnormal_myelination | 0.78401626 |
119 | MP0002116_abnormal_craniofacial_bone | 0.78388120 |
120 | MP0003935_abnormal_craniofacial_develop | 0.78236267 |
121 | MP0005375_adipose_tissue_phenotype | 0.77697501 |
122 | MP0002098_abnormal_vibrissa_morphology | 0.77332470 |
123 | MP0003879_abnormal_hair_cell | 0.76133800 |
124 | MP0003385_abnormal_body_wall | 0.75760422 |
125 | MP0001943_abnormal_respiration | 0.75313150 |
126 | MP0000477_abnormal_intestine_morphology | 0.75074301 |
127 | MP0010769_abnormal_survival | 0.74918808 |
128 | MP0008569_lethality_at_weaning | 0.73986500 |
129 | MP0002066_abnormal_motor_capabilities/c | 0.73719113 |
130 | MP0001502_abnormal_circadian_rhythm | 0.73304196 |
131 | MP0010770_preweaning_lethality | 0.72315440 |
132 | MP0001784_abnormal_fluid_regulation | 0.71679629 |
133 | MP0003121_genomic_imprinting | 0.70864245 |
134 | MP0001293_anophthalmia | 0.70586497 |
135 | MP0002081_perinatal_lethality | 0.70342351 |
136 | MP0005621_abnormal_cell_physiology | 0.70277632 |
137 | MP0001299_abnormal_eye_distance/ | 0.70079251 |
138 | MP0005187_abnormal_penis_morphology | 0.69757393 |
139 | MP0000467_abnormal_esophagus_morphology | 0.69569558 |
140 | MP0002111_abnormal_tail_morphology | 0.69408936 |
141 | MP0003122_maternal_imprinting | 0.66566062 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperacusis (HP:0010780) | 3.89316179 |
2 | Obstructive sleep apnea (HP:0002870) | 3.09697639 |
3 | Insomnia (HP:0100785) | 3.01375723 |
4 | Shallow orbits (HP:0000586) | 2.99797964 |
5 | Cerebral aneurysm (HP:0004944) | 2.73187758 |
6 | Neurofibrillary tangles (HP:0002185) | 2.67573660 |
7 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.67217244 |
8 | Short 4th metacarpal (HP:0010044) | 2.67217244 |
9 | Upper limb amyotrophy (HP:0009129) | 2.66762437 |
10 | Distal upper limb amyotrophy (HP:0007149) | 2.66762437 |
11 | Macroorchidism (HP:0000053) | 2.64930235 |
12 | Overriding aorta (HP:0002623) | 2.63536885 |
13 | Pointed chin (HP:0000307) | 2.57327354 |
14 | Renal duplication (HP:0000075) | 2.55979865 |
15 | Elfin facies (HP:0004428) | 2.55177726 |
16 | Astrocytoma (HP:0009592) | 2.51745987 |
17 | Abnormality of the astrocytes (HP:0100707) | 2.51745987 |
18 | Bowel diverticulosis (HP:0005222) | 2.48839929 |
19 | Broad face (HP:0000283) | 2.47001143 |
20 | Increased density of long bones (HP:0006392) | 2.46633162 |
21 | Abnormality of the lower motor neuron (HP:0002366) | 2.44427212 |
22 | Heterotopia (HP:0002282) | 2.44079217 |
23 | Hand muscle atrophy (HP:0009130) | 2.40560042 |
24 | Ankyloglossia (HP:0010296) | 2.37300639 |
25 | Protrusio acetabuli (HP:0003179) | 2.36820732 |
26 | Ependymoma (HP:0002888) | 2.36150906 |
27 | Ankle clonus (HP:0011448) | 2.34499198 |
28 | Renovascular hypertension (HP:0100817) | 2.33118385 |
29 | Increased nuchal translucency (HP:0010880) | 2.32580047 |
30 | Hammertoe (HP:0001765) | 2.32105736 |
31 | Flat acetabular roof (HP:0003180) | 2.31468587 |
32 | Cerebral inclusion bodies (HP:0100314) | 2.29647130 |
33 | Genu recurvatum (HP:0002816) | 2.25792782 |
34 | Abnormality of oral frenula (HP:0000190) | 2.24599154 |
35 | Myokymia (HP:0002411) | 2.22218380 |
36 | Ulnar bowing (HP:0003031) | 2.21623579 |
37 | Bladder diverticulum (HP:0000015) | 2.18077964 |
38 | Pseudobulbar signs (HP:0002200) | 2.15539834 |
39 | Supranuclear gaze palsy (HP:0000605) | 2.15117276 |
40 | Aplasia of the phalanges of the hand (HP:0009802) | 2.14759213 |
41 | Aplasia involving bones of the extremities (HP:0009825) | 2.14759213 |
42 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.14759213 |
43 | Abnormality of the fingertips (HP:0001211) | 2.12331347 |
44 | Cholecystitis (HP:0001082) | 2.08207001 |
45 | Abnormal gallbladder physiology (HP:0012438) | 2.08207001 |
46 | Peripheral hypomyelination (HP:0007182) | 2.08073939 |
47 | Neoplasm of the heart (HP:0100544) | 2.06747029 |
48 | Termporal pattern (HP:0011008) | 2.05173679 |
49 | Insidious onset (HP:0003587) | 2.05173679 |
50 | Advanced eruption of teeth (HP:0006288) | 2.05109633 |
51 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.03980887 |
52 | Asymmetry of the thorax (HP:0001555) | 2.03879905 |
53 | Precocious puberty (HP:0000826) | 2.02872916 |
54 | Megalencephaly (HP:0001355) | 2.01293116 |
55 | Trigonocephaly (HP:0000243) | 2.00775154 |
56 | Ankle contracture (HP:0006466) | 1.99423217 |
57 | Apathy (HP:0000741) | 1.99291848 |
58 | Abnormality of the 4th metacarpal (HP:0010012) | 1.97985431 |
59 | Flat cornea (HP:0007720) | 1.97364620 |
60 | Enlarged penis (HP:0000040) | 1.96587802 |
61 | Hallux valgus (HP:0001822) | 1.96394710 |
62 | Vertebral arch anomaly (HP:0008438) | 1.95459657 |
63 | Deviation of the hallux (HP:0010051) | 1.95236784 |
64 | Dilatation of the ascending aorta (HP:0005111) | 1.93236396 |
65 | Mitral valve prolapse (HP:0001634) | 1.90958796 |
66 | Neuronal loss in central nervous system (HP:0002529) | 1.90248074 |
67 | Thin ribs (HP:0000883) | 1.89865980 |
68 | Annular pancreas (HP:0001734) | 1.89739983 |
69 | Fibroma (HP:0010614) | 1.88420415 |
70 | Hypercortisolism (HP:0001578) | 1.86844393 |
71 | Generalized hypotonia (HP:0001290) | 1.85738149 |
72 | Achilles tendon contracture (HP:0001771) | 1.85717394 |
73 | Diminished motivation (HP:0000745) | 1.84498889 |
74 | Abnormality of the salivary glands (HP:0010286) | 1.82238724 |
75 | Fibrous tissue neoplasm (HP:0012316) | 1.81759582 |
76 | Subacute progressive viral hepatitis (HP:0006572) | 1.81748415 |
77 | Bowel incontinence (HP:0002607) | 1.81375562 |
78 | Turricephaly (HP:0000262) | 1.81278341 |
79 | Arnold-Chiari malformation (HP:0002308) | 1.81044238 |
80 | Amyotrophic lateral sclerosis (HP:0007354) | 1.80841786 |
81 | Deviation of the thumb (HP:0009603) | 1.79965854 |
82 | Proximal placement of thumb (HP:0009623) | 1.78191107 |
83 | Broad metatarsal (HP:0001783) | 1.78049840 |
84 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.75840931 |
85 | Patellar dislocation (HP:0002999) | 1.75500448 |
86 | Deep venous thrombosis (HP:0002625) | 1.75439023 |
87 | Broad palm (HP:0001169) | 1.75259767 |
88 | Depression (HP:0000716) | 1.75047552 |
89 | High anterior hairline (HP:0009890) | 1.74848889 |
90 | Distal lower limb amyotrophy (HP:0008944) | 1.73834413 |
91 | Germ cell neoplasia (HP:0100728) | 1.73830297 |
92 | Lower limb amyotrophy (HP:0007210) | 1.73599889 |
93 | Cortical dysplasia (HP:0002539) | 1.72116608 |
94 | Reticulocytosis (HP:0001923) | 1.71388083 |
95 | Bowing of the arm (HP:0006488) | 1.71003715 |
96 | Bowed forearm bones (HP:0003956) | 1.71003715 |
97 | Disproportionate tall stature (HP:0001519) | 1.69773087 |
98 | Obsessive-compulsive behavior (HP:0000722) | 1.69249170 |
99 | Lower limb asymmetry (HP:0100559) | 1.68274619 |
100 | Neonatal short-limb short stature (HP:0008921) | 1.67831246 |
101 | Back pain (HP:0003418) | 1.67504959 |
102 | Large earlobe (HP:0009748) | 1.67132703 |
103 | Megalocornea (HP:0000485) | 1.66895187 |
104 | Abnormality of the diencephalon (HP:0010662) | 1.66202087 |
105 | Broad thumb (HP:0011304) | 1.65907815 |
106 | Abnormality of the thoracic spine (HP:0100711) | 1.65248466 |
107 | Long palpebral fissure (HP:0000637) | 1.63397298 |
108 | Relative macrocephaly (HP:0004482) | 1.63393579 |
109 | Basal cell carcinoma (HP:0002671) | 1.62574563 |
110 | Decreased motor nerve conduction velocity (HP:0003431) | 1.62390623 |
111 | Spina bifida occulta (HP:0003298) | 1.61972807 |
112 | Thin bony cortex (HP:0002753) | 1.61901477 |
113 | Distal sensory impairment (HP:0002936) | 1.60708860 |
114 | Aneurysm (HP:0002617) | 1.59962642 |
115 | Glioma (HP:0009733) | 1.59175258 |
116 | Abnormal large intestine physiology (HP:0012700) | 1.58808950 |
117 | Hyperparathyroidism (HP:0000843) | 1.58781577 |
118 | Gastrointestinal carcinoma (HP:0002672) | 1.58452714 |
119 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.58452714 |
120 | Interstitial pulmonary disease (HP:0006530) | 1.58366370 |
121 | Buphthalmos (HP:0000557) | 1.58208328 |
122 | Abnormality of the Achilles tendon (HP:0005109) | 1.58106269 |
123 | Urethral obstruction (HP:0000796) | 1.57886347 |
124 | Metaphyseal cupping (HP:0003021) | 1.57690283 |
125 | Skin tags (HP:0010609) | 1.57510869 |
126 | Alacrima (HP:0000522) | 1.56983724 |
127 | Cellulitis (HP:0100658) | 1.56954100 |
128 | Striae distensae (HP:0001065) | 1.55855292 |
129 | Sacral dimple (HP:0000960) | 1.55770886 |
130 | Radial bowing (HP:0002986) | 1.55627743 |
131 | Persistence of primary teeth (HP:0006335) | 1.55520029 |
132 | Long eyelashes (HP:0000527) | 1.54686464 |
133 | Abnormality of the aortic arch (HP:0012303) | 1.54399721 |
134 | Tracheomalacia (HP:0002779) | 1.54296332 |
135 | Truncus arteriosus (HP:0001660) | 1.53923363 |
136 | Deep palmar crease (HP:0006191) | 1.53593569 |
137 | Thickened helices (HP:0000391) | 1.53569855 |
138 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.53491262 |
139 | Peritonitis (HP:0002586) | 1.53404086 |
140 | Attention deficit hyperactivity disorder (HP:0007018) | 1.52131990 |
141 | Choanal stenosis (HP:0000452) | 1.51719787 |
142 | Hypercalcemia (HP:0003072) | 1.50656530 |
143 | Dysmetric saccades (HP:0000641) | 1.49522655 |
144 | Spastic gait (HP:0002064) | 1.49408566 |
145 | Bronchomalacia (HP:0002780) | 1.47751738 |
146 | Urinary urgency (HP:0000012) | 1.47443667 |
147 | Resting tremor (HP:0002322) | 1.46976756 |
148 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.44195386 |
149 | Papilledema (HP:0001085) | 1.43846177 |
150 | Short phalanx of the thumb (HP:0009660) | 1.43536590 |
151 | Overlapping toe (HP:0001845) | 1.43008735 |
152 | Abnormality of the peritoneum (HP:0002585) | 1.42987674 |
153 | Neoplasm of the oral cavity (HP:0100649) | 1.42792065 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EEF2K | 4.56291857 |
2 | TRIB3 | 4.16062987 |
3 | PRPF4B | 3.27750232 |
4 | MAP3K10 | 3.24142449 |
5 | PKN2 | 3.23448203 |
6 | SMG1 | 3.23418074 |
7 | CDK12 | 2.89490100 |
8 | MAP3K9 | 2.14242647 |
9 | ICK | 2.06902506 |
10 | ALK | 1.98952329 |
11 | SIK1 | 1.94322286 |
12 | PTK6 | 1.79696113 |
13 | SIK2 | 1.78727120 |
14 | MAP4K1 | 1.77966409 |
15 | TYRO3 | 1.74202055 |
16 | LRRK2 | 1.66507119 |
17 | PDGFRA | 1.64207911 |
18 | ERN1 | 1.62792136 |
19 | RIPK1 | 1.62735784 |
20 | BMX | 1.61018671 |
21 | KSR2 | 1.57496295 |
22 | SCYL2 | 1.50558431 |
23 | TAOK1 | 1.48037865 |
24 | PRKD3 | 1.43109633 |
25 | PAK6 | 1.39035664 |
26 | MTOR | 1.24197190 |
27 | EPHB1 | 1.24173395 |
28 | RET | 1.19553897 |
29 | NTRK3 | 1.18936032 |
30 | NTRK1 | 1.18235579 |
31 | GRK6 | 1.17604931 |
32 | MARK1 | 1.13299570 |
33 | STK10 | 1.12892405 |
34 | LATS2 | 1.12540593 |
35 | CAMKK1 | 1.06889115 |
36 | ARAF | 1.06429110 |
37 | TESK2 | 1.05773869 |
38 | MAP3K13 | 1.05219187 |
39 | PAK2 | 1.04946195 |
40 | TTN | 1.04747298 |
41 | PAK4 | 1.04740722 |
42 | PTK2 | 1.03840150 |
43 | MARK2 | 1.02588387 |
44 | DDR2 | 1.00961011 |
45 | EPHA4 | 1.00476266 |
46 | CAMK1G | 0.96362677 |
47 | PASK | 0.96067923 |
48 | NEK2 | 0.93023291 |
49 | PDGFRB | 0.91575343 |
50 | NTRK2 | 0.91559170 |
51 | BRD4 | 0.87127255 |
52 | RPS6KB2 | 0.86550490 |
53 | UHMK1 | 0.83861324 |
54 | MAP3K7 | 0.83476024 |
55 | FGFR4 | 0.82653057 |
56 | FGFR1 | 0.80996574 |
57 | PRKCH | 0.79926899 |
58 | KSR1 | 0.77827181 |
59 | MAP3K8 | 0.77305811 |
60 | CDC7 | 0.74972849 |
61 | MAP3K2 | 0.74650542 |
62 | DMPK | 0.74465453 |
63 | CAMK1D | 0.72622989 |
64 | BRAF | 0.72394909 |
65 | CDK6 | 0.71176020 |
66 | SGK3 | 0.68334559 |
67 | SGK223 | 0.67200373 |
68 | SGK494 | 0.67200373 |
69 | PDPK1 | 0.64126031 |
70 | MAPK10 | 0.61880597 |
71 | RPS6KA2 | 0.61536046 |
72 | RIPK4 | 0.61500090 |
73 | JAK3 | 0.61020126 |
74 | IRAK3 | 0.60825566 |
75 | MINK1 | 0.60040745 |
76 | CDK4 | 0.59531117 |
77 | CLK1 | 0.58977023 |
78 | CDK15 | 0.58645196 |
79 | HIPK2 | 0.58320309 |
80 | HCK | 0.57711000 |
81 | CDK11A | 0.56305331 |
82 | CSF1R | 0.55585291 |
83 | WNK1 | 0.54889857 |
84 | FGFR2 | 0.54014549 |
85 | CDK14 | 0.53865480 |
86 | DAPK2 | 0.52130282 |
87 | CDK18 | 0.51774577 |
88 | EPHA2 | 0.51457417 |
89 | TGFBR1 | 0.51031099 |
90 | FGFR3 | 0.50314513 |
91 | NEK1 | 0.49600199 |
92 | ILK | 0.49065266 |
93 | RPS6KA1 | 0.48758769 |
94 | MAPK11 | 0.48696965 |
95 | MAP3K1 | 0.48691703 |
96 | FGR | 0.48539748 |
97 | CDC42BPA | 0.47625678 |
98 | MAPK12 | 0.47584827 |
99 | STK11 | 0.47462377 |
100 | TESK1 | 0.47364723 |
101 | ROCK2 | 0.46757318 |
102 | CDK7 | 0.46509316 |
103 | RPS6KC1 | 0.46329659 |
104 | RPS6KL1 | 0.46329659 |
105 | CDK5 | 0.45688799 |
106 | PRKD2 | 0.45225764 |
107 | LMTK2 | 0.44247321 |
108 | ZAP70 | 0.43778885 |
109 | FLT3 | 0.43600896 |
110 | AKT2 | 0.43227830 |
111 | TAOK2 | 0.43032791 |
112 | MAP2K2 | 0.42045738 |
113 | DYRK1B | 0.41720676 |
114 | CSNK1D | 0.41571607 |
115 | PAK3 | 0.41514014 |
116 | CHEK1 | 0.41265249 |
117 | PDK1 | 0.40955767 |
118 | EPHB2 | 0.40642184 |
119 | CHUK | 0.40115782 |
120 | RAF1 | 0.39765865 |
121 | SRC | 0.39684807 |
122 | CDK2 | 0.39368619 |
123 | FYN | 0.37756803 |
124 | ERBB2 | 0.37009346 |
125 | GSK3B | 0.36805158 |
126 | MAPK9 | 0.36520054 |
127 | MAPK8 | 0.34927232 |
128 | CAMK4 | 0.33369810 |
129 | PRKAA1 | 0.33080674 |
130 | MET | 0.31333359 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.16668757 |
2 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.96935490 |
3 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.71274132 |
4 | Glioma_Homo sapiens_hsa05214 | 1.66054164 |
5 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.62014835 |
6 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.61511645 |
7 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.59057334 |
8 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.57238452 |
9 | Prion diseases_Homo sapiens_hsa05020 | 1.54223935 |
10 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.52220552 |
11 | Endometrial cancer_Homo sapiens_hsa05213 | 1.49348358 |
12 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.47794297 |
13 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.47570222 |
14 | Colorectal cancer_Homo sapiens_hsa05210 | 1.46828994 |
15 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.46414034 |
16 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.44979260 |
17 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.42896677 |
18 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.40889402 |
19 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.36796459 |
20 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.35948138 |
21 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.32735031 |
22 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.32356567 |
23 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.30040559 |
24 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.28552934 |
25 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.28174515 |
26 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.28093925 |
27 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.26898273 |
28 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.25216415 |
29 | Bladder cancer_Homo sapiens_hsa05219 | 1.24643889 |
30 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.23357706 |
31 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.21236197 |
32 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.19126555 |
33 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.17585441 |
34 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.17509032 |
35 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.16848851 |
36 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.16360123 |
37 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.14469343 |
38 | Focal adhesion_Homo sapiens_hsa04510 | 1.12140260 |
39 | Adherens junction_Homo sapiens_hsa04520 | 1.06163756 |
40 | Axon guidance_Homo sapiens_hsa04360 | 1.06120304 |
41 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.06055246 |
42 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.05729353 |
43 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.05120457 |
44 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.04058703 |
45 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.03802027 |
46 | Gap junction_Homo sapiens_hsa04540 | 1.02710884 |
47 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.02422754 |
48 | Shigellosis_Homo sapiens_hsa05131 | 0.98246160 |
49 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.97539752 |
50 | HTLV-I infection_Homo sapiens_hsa05166 | 0.97410006 |
51 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.96938396 |
52 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.96836044 |
53 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.96591757 |
54 | Long-term potentiation_Homo sapiens_hsa04720 | 0.96103029 |
55 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.95896226 |
56 | Viral myocarditis_Homo sapiens_hsa05416 | 0.95737300 |
57 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.95230055 |
58 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.93598562 |
59 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.93289943 |
60 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.93152216 |
61 | Thyroid cancer_Homo sapiens_hsa05216 | 0.93023616 |
62 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.92662868 |
63 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.92541571 |
64 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.92477497 |
65 | Endocytosis_Homo sapiens_hsa04144 | 0.92366715 |
66 | Platelet activation_Homo sapiens_hsa04611 | 0.90903044 |
67 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.90636949 |
68 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.90424137 |
69 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.90309934 |
70 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.90121608 |
71 | Melanogenesis_Homo sapiens_hsa04916 | 0.89852181 |
72 | Bile secretion_Homo sapiens_hsa04976 | 0.88722278 |
73 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.88143755 |
74 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.87954545 |
75 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.86488191 |
76 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.85998801 |
77 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.85825994 |
78 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.85027892 |
79 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.84399824 |
80 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.83328465 |
81 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.82692983 |
82 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.81718049 |
83 | Lysine degradation_Homo sapiens_hsa00310 | 0.81208936 |
84 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.81177972 |
85 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.80558534 |
86 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.80419026 |
87 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.79314857 |
88 | Hepatitis B_Homo sapiens_hsa05161 | 0.79157259 |
89 | Amoebiasis_Homo sapiens_hsa05146 | 0.79049796 |
90 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.78979442 |
91 | Insulin resistance_Homo sapiens_hsa04931 | 0.78787532 |
92 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.78696808 |
93 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.78542614 |
94 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.78452766 |
95 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.77946933 |
96 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.77853264 |
97 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.77458268 |
98 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.77313076 |
99 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.76088394 |
100 | Cocaine addiction_Homo sapiens_hsa05030 | 0.75838157 |
101 | Tight junction_Homo sapiens_hsa04530 | 0.75568194 |
102 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.75441633 |
103 | Pathways in cancer_Homo sapiens_hsa05200 | 0.75186137 |
104 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.74453182 |
105 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.74341075 |
106 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.74109688 |
107 | Insulin secretion_Homo sapiens_hsa04911 | 0.73916763 |
108 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.73867873 |
109 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.72039591 |
110 | Nicotine addiction_Homo sapiens_hsa05033 | 0.71414524 |
111 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.70547370 |
112 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.70506303 |
113 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.70095584 |
114 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.69915370 |
115 | Long-term depression_Homo sapiens_hsa04730 | 0.69876691 |
116 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.69811757 |
117 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.69411600 |
118 | Prostate cancer_Homo sapiens_hsa05215 | 0.68589711 |
119 | Circadian entrainment_Homo sapiens_hsa04713 | 0.68580109 |
120 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.68198086 |
121 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.68084345 |
122 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.67997334 |
123 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.67575443 |
124 | Salivary secretion_Homo sapiens_hsa04970 | 0.67372901 |
125 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.67031566 |
126 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.66766272 |
127 | Apoptosis_Homo sapiens_hsa04210 | 0.66174610 |
128 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.65839181 |
129 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.65655649 |
130 | Carbon metabolism_Homo sapiens_hsa01200 | 0.65614144 |
131 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.65492628 |
132 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.62916115 |
133 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.61874659 |
134 | GABAergic synapse_Homo sapiens_hsa04727 | 0.61790076 |
135 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.60473812 |