SREK1IP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.32085813
2viral transcription (GO:0019083)6.85155015
3translational termination (GO:0006415)6.63766319
4ribosomal small subunit biogenesis (GO:0042274)6.16095339
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.95454625
6cotranslational protein targeting to membrane (GO:0006613)5.95154311
7protein targeting to ER (GO:0045047)5.86653894
8establishment of protein localization to endoplasmic reticulum (GO:0072599)5.56440710
9protein localization to endoplasmic reticulum (GO:0070972)5.52295198
10mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.37569549
11translational elongation (GO:0006414)5.32891641
12maturation of SSU-rRNA (GO:0030490)5.31249306
13GTP biosynthetic process (GO:0006183)5.17727049
14mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.16616572
15viral life cycle (GO:0019058)5.10905069
16ATP synthesis coupled proton transport (GO:0015986)5.05677248
17energy coupled proton transport, down electrochemical gradient (GO:0015985)5.05677248
18cellular protein complex disassembly (GO:0043624)4.88693232
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.80669781
20proteasome assembly (GO:0043248)4.74890499
21respiratory electron transport chain (GO:0022904)4.65842968
22ribosomal large subunit biogenesis (GO:0042273)4.59100705
23electron transport chain (GO:0022900)4.53726185
24translational initiation (GO:0006413)4.51518242
25respiratory chain complex IV assembly (GO:0008535)4.39814225
26UTP biosynthetic process (GO:0006228)4.32400121
27mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.13183378
28mitochondrial respiratory chain complex I assembly (GO:0032981)4.13183378
29NADH dehydrogenase complex assembly (GO:0010257)4.13183378
30protein complex biogenesis (GO:0070271)4.12537993
31protein complex disassembly (GO:0043241)4.08098767
32translation (GO:0006412)4.04857434
33guanosine-containing compound biosynthetic process (GO:1901070)3.97402883
34termination of RNA polymerase III transcription (GO:0006386)3.92183242
35transcription elongation from RNA polymerase III promoter (GO:0006385)3.92183242
36UTP metabolic process (GO:0046051)3.87267269
37macromolecular complex disassembly (GO:0032984)3.83946671
38mitochondrial respiratory chain complex assembly (GO:0033108)3.75460474
39chaperone-mediated protein transport (GO:0072321)3.69094602
40DNA damage response, detection of DNA damage (GO:0042769)3.68519353
41platelet dense granule organization (GO:0060155)3.66068618
42protein targeting to membrane (GO:0006612)3.64872882
43CTP biosynthetic process (GO:0006241)3.64288679
44CTP metabolic process (GO:0046036)3.64288679
45negative regulation of B cell apoptotic process (GO:0002903)3.58717579
46cytochrome complex assembly (GO:0017004)3.50746159
47nuclear-transcribed mRNA catabolic process (GO:0000956)3.48361662
48neuron fate determination (GO:0048664)3.46657902
49water-soluble vitamin biosynthetic process (GO:0042364)3.45024443
50nucleoside diphosphate phosphorylation (GO:0006165)3.43819493
51behavioral response to nicotine (GO:0035095)3.41954367
52oxidative phosphorylation (GO:0006119)3.41716454
53ribonucleoprotein complex biogenesis (GO:0022613)3.40017518
54mRNA catabolic process (GO:0006402)3.32570065
55daunorubicin metabolic process (GO:0044597)3.31537491
56polyketide metabolic process (GO:0030638)3.31537491
57doxorubicin metabolic process (GO:0044598)3.31537491
58aerobic respiration (GO:0009060)3.31464644
59cellular component biogenesis (GO:0044085)3.27684712
60DNA deamination (GO:0045006)3.27467000
61inner mitochondrial membrane organization (GO:0007007)3.25469487
62regulation of mitochondrial translation (GO:0070129)3.24837235
63somite development (GO:0061053)3.24555595
64establishment of protein localization to mitochondrial membrane (GO:0090151)3.24243586
657-methylguanosine RNA capping (GO:0009452)3.20635157
66RNA capping (GO:0036260)3.20635157
67protein neddylation (GO:0045116)3.16576958
68DNA replication checkpoint (GO:0000076)3.14382013
69CENP-A containing nucleosome assembly (GO:0034080)3.12058812
70pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.11944823
71pseudouridine synthesis (GO:0001522)3.10060168
72kinetochore organization (GO:0051383)3.08679681
73deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.08565305
74purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.08248734
75mitochondrial DNA replication (GO:0006264)3.07801158
76purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)3.07544661
777-methylguanosine mRNA capping (GO:0006370)3.07250100
78cilium movement (GO:0003341)3.06594988
79protein-cofactor linkage (GO:0018065)3.05972729
80negative regulation of DNA-dependent DNA replication (GO:2000104)3.04527750
81chromatin remodeling at centromere (GO:0031055)3.03995980
82nonmotile primary cilium assembly (GO:0035058)3.03972559
83kinetochore assembly (GO:0051382)3.02694942
84pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.02192796
85purine nucleoside triphosphate biosynthetic process (GO:0009145)3.01678066
86telomere maintenance via semi-conservative replication (GO:0032201)2.98522957
87histone exchange (GO:0043486)2.98493488
88RNA catabolic process (GO:0006401)2.97884039
89DNA-dependent DNA replication (GO:0006261)2.96035774
90replication fork processing (GO:0031297)2.95224836
91pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.93865738
92somite rostral/caudal axis specification (GO:0032525)2.88343287
93nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.87568049
94quinone biosynthetic process (GO:1901663)2.87005168
95ubiquinone biosynthetic process (GO:0006744)2.87005168
96spliceosomal complex assembly (GO:0000245)2.86666157
97pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.85623640
98regulation of memory T cell differentiation (GO:0043380)2.83911564
99exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.83017062
100establishment of integrated proviral latency (GO:0075713)2.83002204
101rRNA processing (GO:0006364)2.79603957
102telomere maintenance via recombination (GO:0000722)2.79539878
103centriole replication (GO:0007099)2.77680722
104DNA replication-independent nucleosome organization (GO:0034724)2.76962477
105DNA replication-independent nucleosome assembly (GO:0006336)2.76962477
106epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.76681679
107positive regulation of gastrulation (GO:2000543)2.75961530
108protein targeting to mitochondrion (GO:0006626)2.75883267
109regulation of mesoderm development (GO:2000380)2.75723458
110spliceosomal snRNP assembly (GO:0000387)2.75251554
111substrate-independent telencephalic tangential migration (GO:0021826)2.73831936
112substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.73831936
113kidney morphogenesis (GO:0060993)2.71019454
114deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.70779657
115axonemal dynein complex assembly (GO:0070286)2.70616715
116intracellular protein transmembrane import (GO:0044743)2.70511807
117transcription-coupled nucleotide-excision repair (GO:0006283)2.69156280
118epithelial cilium movement (GO:0003351)2.67881922
119ribonucleoside triphosphate biosynthetic process (GO:0009201)2.67461898
120positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.66713682
121rRNA metabolic process (GO:0016072)2.65764241
122pyrimidine nucleotide catabolic process (GO:0006244)2.65005982
123deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.64159388
124DNA double-strand break processing (GO:0000729)2.62706786
125nucleobase-containing small molecule interconversion (GO:0015949)2.60826457
126intraciliary transport (GO:0042073)2.60676102
127nucleoside diphosphate metabolic process (GO:0009132)2.58147798
128sequestering of actin monomers (GO:0042989)2.57170748
129retinal ganglion cell axon guidance (GO:0031290)2.52161578
130RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.49835773
131tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.49835773
132protein targeting (GO:0006605)2.49222901
133thalamus development (GO:0021794)2.47070292
134hydrogen ion transmembrane transport (GO:1902600)2.45232898
135protein K6-linked ubiquitination (GO:0085020)2.44970045
136rRNA modification (GO:0000154)2.44656823
137establishment of protein localization to membrane (GO:0090150)2.42800912
138negative regulation of transcription regulatory region DNA binding (GO:2000678)2.41497391
139resolution of meiotic recombination intermediates (GO:0000712)2.40979266
140ATP biosynthetic process (GO:0006754)2.39621556
141establishment of protein localization to organelle (GO:0072594)2.39105022
142regulation of DNA endoreduplication (GO:0032875)2.38906089

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.37635473
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.26837867
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.93192630
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.70627951
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.65604578
6RBPJ_22232070_ChIP-Seq_NCS_Mouse3.51778188
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.30086178
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.13826249
9E2F7_22180533_ChIP-Seq_HELA_Human2.90384815
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.87351760
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.70834397
12ELK1_19687146_ChIP-ChIP_HELA_Human2.70717553
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.63833836
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.63636374
15JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.60674497
16ZNF274_21170338_ChIP-Seq_K562_Hela2.40362315
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.39949714
18SALL1_21062744_ChIP-ChIP_HESCs_Human2.33148875
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.30168999
20VDR_23849224_ChIP-Seq_CD4+_Human2.26419682
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.26304657
22MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.25672745
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.23107457
24FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.20479101
25SRF_21415370_ChIP-Seq_HL-1_Mouse2.16125698
26ELF1_17652178_ChIP-ChIP_JURKAT_Human2.12169227
27MYC_18358816_ChIP-ChIP_MESCs_Mouse2.10842938
28FUS_26573619_Chip-Seq_HEK293_Human2.07454306
29DCP1A_22483619_ChIP-Seq_HELA_Human2.06455569
30BP1_19119308_ChIP-ChIP_Hs578T_Human1.98969613
31HOXB4_20404135_ChIP-ChIP_EML_Mouse1.96604159
32EWS_26573619_Chip-Seq_HEK293_Human1.94217418
33* FOXP3_21729870_ChIP-Seq_TREG_Human1.89197788
34MYC_19030024_ChIP-ChIP_MESCs_Mouse1.88128957
35CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.86201970
36EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.85464280
37MYC_18940864_ChIP-ChIP_HL60_Human1.83968911
38MYC_19079543_ChIP-ChIP_MESCs_Mouse1.82829454
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.82527656
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.80310391
41* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.78033994
42TTF2_22483619_ChIP-Seq_HELA_Human1.76279707
43POU3F2_20337985_ChIP-ChIP_501MEL_Human1.74801544
44PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.64271637
45SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.63224836
46ELK1_22589737_ChIP-Seq_MCF10A_Human1.62893315
47FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.61739990
48FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.61728337
49ERG_20887958_ChIP-Seq_HPC-7_Mouse1.57182663
50E2F1_18555785_ChIP-Seq_MESCs_Mouse1.56496463
51XRN2_22483619_ChIP-Seq_HELA_Human1.56001353
52CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.53312022
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.50459561
54SOX2_16153702_ChIP-ChIP_HESCs_Human1.49431307
55GBX2_23144817_ChIP-Seq_PC3_Human1.44846008
56PCGF2_27294783_Chip-Seq_ESCs_Mouse1.42148332
57CTBP2_25329375_ChIP-Seq_LNCAP_Human1.40078427
58TP63_19390658_ChIP-ChIP_HaCaT_Human1.37314045
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35688052
60NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.34655532
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.31448810
62BMI1_23680149_ChIP-Seq_NPCS_Mouse1.30365594
63GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.25686652
64VDR_22108803_ChIP-Seq_LS180_Human1.25117401
65SOX2_18555785_ChIP-Seq_MESCs_Mouse1.23277659
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.21643167
67ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.21346400
68GABP_19822575_ChIP-Seq_HepG2_Human1.21342328
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.18174103
70TP53_22573176_ChIP-Seq_HFKS_Human1.17877280
71NELFA_20434984_ChIP-Seq_ESCs_Mouse1.17397098
72ZFP57_27257070_Chip-Seq_ESCs_Mouse1.16981830
73MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.16478204
74MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.16248680
75NANOG_16153702_ChIP-ChIP_HESCs_Human1.16036116
76SMAD3_21741376_ChIP-Seq_EPCs_Human1.15626068
77P300_19829295_ChIP-Seq_ESCs_Human1.15092817
78IRF1_19129219_ChIP-ChIP_H3396_Human1.15000534
79IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.14569953
80CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.14413231
81EZH2_27304074_Chip-Seq_ESCs_Mouse1.14217202
82ER_23166858_ChIP-Seq_MCF-7_Human1.13412446
83EZH2_22144423_ChIP-Seq_EOC_Human1.12833401
84TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12597862
85RNF2_27304074_Chip-Seq_NSC_Mouse1.11842736
86UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11520567
87ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09430485
88CBX2_27304074_Chip-Seq_ESCs_Mouse1.09306878
89AR_21909140_ChIP-Seq_LNCAP_Human1.09216716
90KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.07731850
91POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06793660
92YY1_21170310_ChIP-Seq_MESCs_Mouse1.05683436
93SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05626631
94FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03681928
95TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02719494
96POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02719494
97THAP11_20581084_ChIP-Seq_MESCs_Mouse1.02660739
98CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.02214068
99CBP_20019798_ChIP-Seq_JUKART_Human1.01937284
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01937284
101GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.00627934
102TAF15_26573619_Chip-Seq_HEK293_Human0.99997700
103RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.98644127
104SUZ12_27294783_Chip-Seq_NPCs_Mouse0.98239303
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97850440
106NFE2_27457419_Chip-Seq_LIVER_Mouse0.97493250
107RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95834864
108NANOG_19829295_ChIP-Seq_ESCs_Human0.95358358
109SOX2_19829295_ChIP-Seq_ESCs_Human0.95358358
110PCGF2_27294783_Chip-Seq_NPCs_Mouse0.95034220
111POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.94051737
112GATA1_22025678_ChIP-Seq_K562_Human0.93168776
113BCAT_22108803_ChIP-Seq_LS180_Human0.93035783
114P53_22387025_ChIP-Seq_ESCs_Mouse0.92837995
115AR_25329375_ChIP-Seq_VCAP_Human0.92772720
116AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92752985
117KLF5_20875108_ChIP-Seq_MESCs_Mouse0.92335524
118TAL1_26923725_Chip-Seq_HPCs_Mouse0.92237833
119HTT_18923047_ChIP-ChIP_STHdh_Human0.92036801
120LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.91666350
121GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90990414
122EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.89699138
123E2F1_21310950_ChIP-Seq_MCF-7_Human0.88589582
124IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.86739235
125IGF1R_20145208_ChIP-Seq_DFB_Human0.84037736
126EZH2_27294783_Chip-Seq_NPCs_Mouse0.83784508
127PIAS1_25552417_ChIP-Seq_VCAP_Human0.82449161
128MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.82317073
129CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.81444102
130EGR1_23403033_ChIP-Seq_LIVER_Mouse0.81274725
131CTBP1_25329375_ChIP-Seq_LNCAP_Human0.81132205
132KAP1_22055183_ChIP-Seq_ESCs_Mouse0.80620041

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.17031176
2MP0002163_abnormal_gland_morphology3.25594924
3MP0003136_yellow_coat_color3.20899904
4MP0006292_abnormal_olfactory_placode2.82205503
5MP0009697_abnormal_copulation2.80158267
6MP0005379_endocrine/exocrine_gland_phen2.76040711
7MP0001188_hyperpigmentation2.60651319
8MP0000566_synostosis2.60613153
9MP0003890_abnormal_embryonic-extraembry2.48301949
10MP0002139_abnormal_hepatobiliary_system2.40884563
11MP0002234_abnormal_pharynx_morphology2.40105837
12MP0008789_abnormal_olfactory_epithelium2.37492608
13MP0003186_abnormal_redox_activity2.36178868
14MP0001293_anophthalmia2.34957861
15MP0003122_maternal_imprinting2.28550343
16MP0002102_abnormal_ear_morphology2.26137048
17MP0003693_abnormal_embryo_hatching2.14415250
18MP0001853_heart_inflammation2.07301404
19MP0000049_abnormal_middle_ear2.06847918
20MP0005499_abnormal_olfactory_system2.03243771
21MP0005394_taste/olfaction_phenotype2.03243771
22MP0005409_darkened_coat_color1.92614903
23MP0000569_abnormal_digit_pigmentation1.90082387
24MP0002396_abnormal_hematopoietic_system1.87958164
25MP0003123_paternal_imprinting1.76620666
26MP0009250_abnormal_appendicular_skeleto1.71017172
27MP0005174_abnormal_tail_pigmentation1.69626030
28MP0003283_abnormal_digestive_organ1.67713029
29MP0000778_abnormal_nervous_system1.66387089
30MP0002653_abnormal_ependyma_morphology1.65846058
31MP0003880_abnormal_central_pattern1.63859302
32MP0003724_increased_susceptibility_to1.63570151
33MP0003718_maternal_effect1.61085377
34MP0004957_abnormal_blastocyst_morpholog1.57754420
35MP0001286_abnormal_eye_development1.56630804
36MP0002938_white_spotting1.56252319
37MP0005551_abnormal_eye_electrophysiolog1.51900428
38MP0002277_abnormal_respiratory_mucosa1.51880467
39MP0001529_abnormal_vocalization1.51736389
40MP0004133_heterotaxia1.50705521
41MP0001905_abnormal_dopamine_level1.47947681
42MP0005408_hypopigmentation1.47833695
43MP0003646_muscle_fatigue1.46408041
44MP0000372_irregular_coat_pigmentation1.45067089
45MP0002233_abnormal_nose_morphology1.44117564
46MP0008004_abnormal_stomach_pH1.43346187
47MP0002249_abnormal_larynx_morphology1.43075896
48MP0008932_abnormal_embryonic_tissue1.42973864
49MP0002837_dystrophic_cardiac_calcinosis1.42674916
50MP0003787_abnormal_imprinting1.41370341
51MP0010030_abnormal_orbit_morphology1.39640637
52MP0002095_abnormal_skin_pigmentation1.39283884
53MP0002160_abnormal_reproductive_system1.37517923
54MP0004484_altered_response_of1.35421418
55MP0003121_genomic_imprinting1.34599561
56MP0006036_abnormal_mitochondrial_physio1.31147220
57MP0002148_abnormal_hypersensitivity_rea1.30894344
58MP0003119_abnormal_digestive_system1.29762070
59MP0009785_altered_susceptibility_to1.29518959
60MP0001986_abnormal_taste_sensitivity1.29411277
61MP0005084_abnormal_gallbladder_morpholo1.29190463
62MP0006054_spinal_hemorrhage1.24401326
63MP0005253_abnormal_eye_physiology1.24040253
64MP0003191_abnormal_cellular_cholesterol1.23830731
65MP0002638_abnormal_pupillary_reflex1.23449922
66MP0010094_abnormal_chromosome_stability1.21461574
67MP0004381_abnormal_hair_follicle1.21429735
68MP0002132_abnormal_respiratory_system1.19418489
69MP0009053_abnormal_anal_canal1.19386989
70MP0002177_abnormal_outer_ear1.18810876
71MP0001346_abnormal_lacrimal_gland1.14754955
72MP0005389_reproductive_system_phenotype1.12266229
73MP0003950_abnormal_plasma_membrane1.12223937
74MP0004885_abnormal_endolymph1.11249253
75MP0005195_abnormal_posterior_eye1.10849754
76MP0005171_absent_coat_pigmentation1.09583714
77MP0003315_abnormal_perineum_morphology1.09414713
78MP0003077_abnormal_cell_cycle1.09326411
79MP0004742_abnormal_vestibular_system1.07571909
80MP0003755_abnormal_palate_morphology1.07464282
81MP0000490_abnormal_crypts_of1.07316250
82MP0000015_abnormal_ear_pigmentation1.06712833
83MP0005391_vision/eye_phenotype1.06577573
84MP0003937_abnormal_limbs/digits/tail_de1.04449866
85MP0001663_abnormal_digestive_system1.04244684
86MP0008007_abnormal_cellular_replicative1.03391927
87MP0002210_abnormal_sex_determination1.02898002
88MP0002697_abnormal_eye_size1.02553170
89MP0002557_abnormal_social/conspecific_i1.01970337
90MP0005075_abnormal_melanosome_morpholog1.01846010
91MP0003938_abnormal_ear_development1.01375699
92MP0009384_cardiac_valve_regurgitation1.00648797
93MP0008995_early_reproductive_senescence1.00401709
94MP0003878_abnormal_ear_physiology0.99650989
95MP0005377_hearing/vestibular/ear_phenot0.99650989
96MP0008877_abnormal_DNA_methylation0.97237067
97MP0001984_abnormal_olfaction0.96919047
98MP0000631_abnormal_neuroendocrine_gland0.96306221
99MP0002282_abnormal_trachea_morphology0.95721700
100MP0004145_abnormal_muscle_electrophysio0.95593354
101MP0002736_abnormal_nociception_after0.95341537
102MP0000647_abnormal_sebaceous_gland0.94539661
103MP0001485_abnormal_pinna_reflex0.93554143
104MP0002752_abnormal_somatic_nervous0.93165891
105MP0004215_abnormal_myocardial_fiber0.91563745
106MP0006035_abnormal_mitochondrial_morpho0.90601773
107MP0001324_abnormal_eye_pigmentation0.90361691
108MP0005646_abnormal_pituitary_gland0.89990086
109MP0003195_calcinosis0.89678322
110MP0005451_abnormal_body_composition0.89478166
111MP0008058_abnormal_DNA_repair0.89413723
112MP0009745_abnormal_behavioral_response0.88901168
113MP0001119_abnormal_female_reproductive0.88442021
114MP0000427_abnormal_hair_cycle0.88234869
115MP0009046_muscle_twitch0.87712324
116MP0003385_abnormal_body_wall0.87049749
117MP0010386_abnormal_urinary_bladder0.86798058
118MP0003861_abnormal_nervous_system0.83382079
119MP0000026_abnormal_inner_ear0.83106837
120MP0002184_abnormal_innervation0.82562079
121MP0005381_digestive/alimentary_phenotyp0.81765224
122MP0010368_abnormal_lymphatic_system0.81263610
123MP0004808_abnormal_hematopoietic_stem0.80818756
124MP0002272_abnormal_nervous_system0.80698422
125MP0000653_abnormal_sex_gland0.80623344
126MP0000613_abnormal_salivary_gland0.79653141
127MP0005645_abnormal_hypothalamus_physiol0.79534422
128MP0003567_abnormal_fetal_cardiomyocyte0.79149868
129MP0003011_delayed_dark_adaptation0.79083504
130MP0005164_abnormal_response_to0.79006682
131MP0006072_abnormal_retinal_apoptosis0.78546637
132MP0002111_abnormal_tail_morphology0.78294069
133MP0005187_abnormal_penis_morphology0.77732984
134MP0008057_abnormal_DNA_replication0.77546549
135MP0004883_abnormal_blood_vessel0.77021503
136MP0001145_abnormal_male_reproductive0.76132505
137MP0002928_abnormal_bile_duct0.75983740
138MP0004142_abnormal_muscle_tone0.75577902
139MP0000955_abnormal_spinal_cord0.74341353
140MP0006276_abnormal_autonomic_nervous0.73215608
141MP0004147_increased_porphyrin_level0.72429093
142MP0002092_abnormal_eye_morphology0.72180705
143MP0002127_abnormal_cardiovascular_syste0.70583135
144MP0002876_abnormal_thyroid_physiology0.70318031
145MP0001879_abnormal_lymphatic_vessel0.69956646
146MP0003828_pulmonary_edema0.69760340
147MP0001968_abnormal_touch/_nociception0.68733985
148MP0000163_abnormal_cartilage_morphology0.68529944
149MP0002751_abnormal_autonomic_nervous0.64274873
150MP0005388_respiratory_system_phenotype0.63957716
151MP0002133_abnormal_respiratory_system0.63957716
152MP0001919_abnormal_reproductive_system0.62867159

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.29608776
2Increased hepatocellular lipid droplets (HP:0006565)5.24328185
3Abnormal mitochondria in muscle tissue (HP:0008316)4.93799131
4Mitochondrial inheritance (HP:0001427)4.92645341
5Lipid accumulation in hepatocytes (HP:0006561)4.72756752
6Renal Fanconi syndrome (HP:0001994)4.49899212
7Abnormality of cells of the erythroid lineage (HP:0012130)4.49050877
8Progressive macrocephaly (HP:0004481)4.44691668
9Hepatocellular necrosis (HP:0001404)4.43060810
10Abnormal ciliary motility (HP:0012262)4.41836667
11Acute encephalopathy (HP:0006846)4.37407285
12Abnormal number of erythroid precursors (HP:0012131)4.26385930
13Increased CSF lactate (HP:0002490)4.22856013
14Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.12403788
15Increased intramyocellular lipid droplets (HP:0012240)4.06030635
16Hepatic necrosis (HP:0002605)3.95149725
17Abnormal respiratory motile cilium physiology (HP:0012261)3.87426190
18Reticulocytopenia (HP:0001896)3.87360217
19Exertional dyspnea (HP:0002875)3.76870072
20Septo-optic dysplasia (HP:0100842)3.67445546
21Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.57373872
22Increased muscle lipid content (HP:0009058)3.38718172
23Macrocytic anemia (HP:0001972)3.36345949
24Respiratory difficulties (HP:0002880)3.34394085
25Colon cancer (HP:0003003)3.28347963
26Abnormal respiratory motile cilium morphology (HP:0005938)3.26760075
27Abnormal respiratory epithelium morphology (HP:0012253)3.26760075
28Exercise intolerance (HP:0003546)3.26495645
29Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.18793538
30Abnormality of renal resorption (HP:0011038)3.17579328
31Pallor (HP:0000980)3.07409439
323-Methylglutaconic aciduria (HP:0003535)3.06123838
33Decreased activity of mitochondrial respiratory chain (HP:0008972)2.96775900
34Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.96775900
35True hermaphroditism (HP:0010459)2.96282893
36Pancreatic fibrosis (HP:0100732)2.88959146
37Cerebral edema (HP:0002181)2.88347258
38Increased serum lactate (HP:0002151)2.84674147
39Optic disc pallor (HP:0000543)2.78914945
40Rhinitis (HP:0012384)2.77657197
41Lactic acidosis (HP:0003128)2.74387408
42Aplastic anemia (HP:0001915)2.66992859
43Abnormal hemoglobin (HP:0011902)2.66848160
44Optic nerve hypoplasia (HP:0000609)2.63978251
45Respiratory failure (HP:0002878)2.62470886
46Aplasia/Hypoplasia of the sacrum (HP:0008517)2.62418411
47Congenital, generalized hypertrichosis (HP:0004540)2.61237499
48Pancreatic cysts (HP:0001737)2.60672761
49Concave nail (HP:0001598)2.57608130
50Dynein arm defect of respiratory motile cilia (HP:0012255)2.53753487
51Absent/shortened dynein arms (HP:0200106)2.53753487
52Oligodactyly (hands) (HP:0001180)2.52770653
53Abnormality of the labia minora (HP:0012880)2.52631344
54Glycosuria (HP:0003076)2.50942575
55Abnormality of urine glucose concentration (HP:0011016)2.50942575
56Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.46140129
57Nasolacrimal duct obstruction (HP:0000579)2.45597971
58Hyperphosphaturia (HP:0003109)2.45288446
59Maternal diabetes (HP:0009800)2.44126572
60Amniotic constriction ring (HP:0009775)2.42354982
61Abnormality of placental membranes (HP:0011409)2.42354982
62Congenital stationary night blindness (HP:0007642)2.42131169
63Abnormality of secondary sexual hair (HP:0009888)2.37493980
64Abnormality of the axillary hair (HP:0100134)2.37493980
65Redundant skin (HP:0001582)2.30727809
66Medial flaring of the eyebrow (HP:0010747)2.27053626
67Rib fusion (HP:0000902)2.24540884
68Absent septum pellucidum (HP:0001331)2.24145276
69Parakeratosis (HP:0001036)2.23152059
70Ridged nail (HP:0001807)2.22884363
71Absent thumb (HP:0009777)2.17482511
72Pulmonary artery stenosis (HP:0004415)2.17409446
73Partial duplication of thumb phalanx (HP:0009944)2.16976815
74Nephronophthisis (HP:0000090)2.16791192
75Anophthalmia (HP:0000528)2.15096883
76Type I transferrin isoform profile (HP:0003642)2.14633105
77Molar tooth sign on MRI (HP:0002419)2.11266967
78Abnormality of midbrain morphology (HP:0002418)2.11266967
79Leukodystrophy (HP:0002415)2.09303721
80Short middle phalanx of the 5th finger (HP:0004220)2.05962675
81Aplasia/Hypoplasia of the tongue (HP:0010295)2.05721065
82Methylmalonic acidemia (HP:0002912)2.05597062
83Aplasia/Hypoplasia of the uvula (HP:0010293)2.05551980
84Stenosis of the external auditory canal (HP:0000402)2.04303190
85Postaxial foot polydactyly (HP:0001830)2.02413765
86Partial duplication of the phalanx of hand (HP:0009999)2.01977627
87Esophageal atresia (HP:0002032)2.00950116
88Meckel diverticulum (HP:0002245)1.98969974
89Chronic hepatic failure (HP:0100626)1.98926392
90Abolished electroretinogram (ERG) (HP:0000550)1.96624463
91Cystic liver disease (HP:0006706)1.96244214
92Microglossia (HP:0000171)1.95381216
93Depressed nasal ridge (HP:0000457)1.95188710
94Male pseudohermaphroditism (HP:0000037)1.94362913
95Pendular nystagmus (HP:0012043)1.93880235
96Intestinal atresia (HP:0011100)1.92996340
97Abnormality of the renal cortex (HP:0011035)1.92630087
98Metaphyseal dysplasia (HP:0100255)1.92197435
99Supernumerary spleens (HP:0009799)1.91204267
100Abnormality of the heme biosynthetic pathway (HP:0010472)1.89870662
101Abnormal number of incisors (HP:0011064)1.89400704
102Anencephaly (HP:0002323)1.88989929
103Oligodactyly (HP:0012165)1.88822812
104Growth hormone deficiency (HP:0000824)1.88155905
105Congenital primary aphakia (HP:0007707)1.87877151
106Abnormality of the ileum (HP:0001549)1.85753916
107Abnormal biliary tract physiology (HP:0012439)1.85189758
108Bile duct proliferation (HP:0001408)1.85189758
109Hypoplastic pelvis (HP:0008839)1.84912605
110Abnormality of the septum pellucidum (HP:0007375)1.83960830
111Abnormality of chromosome stability (HP:0003220)1.82268656
112Gastrointestinal atresia (HP:0002589)1.81587511
113Oral leukoplakia (HP:0002745)1.81341061
114Abnormality of the lacrimal duct (HP:0011481)1.81240911
115Microvesicular hepatic steatosis (HP:0001414)1.79994015
116Bony spicule pigmentary retinopathy (HP:0007737)1.79914348
117Type 2 muscle fiber atrophy (HP:0003554)1.79363130
118Muscle fiber atrophy (HP:0100295)1.79094145
119Bronchiectasis (HP:0002110)1.78148589
120Genital tract atresia (HP:0001827)1.77680388
121Vaginal atresia (HP:0000148)1.76600044
122Type II lissencephaly (HP:0007260)1.76381374
123Methylmalonic aciduria (HP:0012120)1.76042135
124Abnormal urine phosphate concentration (HP:0012599)1.75923755
125Abnormality of the renal medulla (HP:0100957)1.75566026
126Postaxial hand polydactyly (HP:0001162)1.75262733
127Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.74597019
128Ectopic kidney (HP:0000086)1.74000807
129Absent rod-and cone-mediated responses on ERG (HP:0007688)1.73743533
13011 pairs of ribs (HP:0000878)1.73740561
131Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.73347263
132Pancytopenia (HP:0001876)1.73113202
133Gait imbalance (HP:0002141)1.72887032
134Patchy hypopigmentation of hair (HP:0011365)1.72764551
135Nonprogressive disorder (HP:0003680)1.72235324
136Chromsome breakage (HP:0040012)1.71384192
137Hyperglycinemia (HP:0002154)1.71369244
138Abnormal rod and cone electroretinograms (HP:0008323)1.70148977
139Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.69949884
140Furrowed tongue (HP:0000221)1.69891218
141Aplasia/Hypoplasia of the spleen (HP:0010451)1.69652086
142Preaxial hand polydactyly (HP:0001177)1.67986797
143Asplenia (HP:0001746)1.66502081
144Holoprosencephaly (HP:0001360)1.66205228
145Triphalangeal thumb (HP:0001199)1.64905832
146Abnormality of the nasolacrimal system (HP:0000614)1.62204831
147Nephrogenic diabetes insipidus (HP:0009806)1.61348434
148X-linked dominant inheritance (HP:0001423)1.59711819
149Renal tubular dysfunction (HP:0000124)1.59615376
150Abnormality of the phalanges of the 5th finger (HP:0004213)1.59213230
151Sclerocornea (HP:0000647)1.57678000
152Neoplasm of head and neck (HP:0012288)1.55569197
153Esophageal neoplasm (HP:0100751)1.55569197

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MUSK4.49797535
2PBK3.53023007
3TLK13.39956694
4NME23.27522400
5CASK3.17922014
6STK163.00529291
7MKNK22.96622569
8VRK22.83679036
9WNK32.80332051
10MKNK12.47815826
11PNCK2.26603238
12TNIK2.21299681
13CCNB12.11702773
14TRIM282.06012245
15WEE12.01834375
16EIF2AK11.99805830
17VRK11.96144698
18ACVR1B1.93173056
19NME11.91326265
20DYRK21.90908282
21PIM21.84848945
22EPHB21.80476505
23MAP4K21.77136335
24WNK41.70476122
25BUB11.67871808
26GRK71.67559887
27CDK191.58501896
28MAP3K41.57843265
29BMPR21.54704419
30EIF2AK31.54021262
31STK38L1.53887527
32PLK41.52869491
33CDK81.52441414
34CDC71.50343587
35SRPK11.48921820
36BRAF1.36860841
37NEK11.36543406
38PINK11.36368912
39TAOK31.33579191
40MOS1.33326582
41TAF11.33002291
42KIT1.30473964
43PIK3CG1.26654544
44NEK91.21606557
45STK391.20583116
46ARAF1.18165339
47MAP2K71.14372214
48ADRBK21.12628968
49STK31.10508459
50TEC1.02572167
51MST41.00884595
52IRAK10.98071637
53BRSK20.97433781
54MAP3K120.96928663
55NUAK10.95327841
56CDK30.94439547
57EIF2AK20.93944588
58INSRR0.90958852
59IRAK40.89944277
60YES10.88698203
61PLK20.88668687
62TGFBR20.87551229
63PRKCG0.87054540
64PIK3CA0.86329559
65ABL20.85651612
66AURKB0.84528788
67MYLK0.83369079
68DYRK30.82165075
69IKBKB0.81800247
70PAK30.81625828
71BMPR1B0.79139997
72TIE10.77233421
73PLK10.75442153
74CSNK2A10.67067647
75RIPK40.66349601
76CAMK1G0.64951530
77AURKA0.63894222
78NEK20.63092792
79ADRBK10.61752391
80CSNK1E0.61317764
81NTRK20.61238379
82TGFBR10.60080673
83PRKCE0.59757876
84ERBB30.58041272
85CDK70.57975241
86RPS6KA40.57241669
87BCR0.57227105
88CHEK20.56463700
89ATM0.56310298
90PLK30.54362825
91MINK10.53899001
92ZAK0.53786998
93FGFR20.52898305
94MAPK130.52634065
95CSNK1G10.52016989
96CSNK1G20.51781530
97RPS6KA50.51254558
98PDK20.50429991
99MAP3K130.50340441
100STK240.49069883
101MAP3K60.48998353
102NLK0.48961593
103CSNK2A20.48762114
104CAMK10.48623706
105BTK0.48600028
106DAPK20.46820380
107MAPK40.46069617
108CHEK10.45998688
109MAPK150.45979250
110TTK0.45902293
111OBSCN0.44984485
112PASK0.44840109
113LYN0.43755236
114IRAK30.43400176
115SYK0.43361530
116ILK0.43112042
117CSNK1G30.42978382
118FES0.42723148
119BRSK10.42501138
120ERBB20.41881079
121STK40.41849911
122FRK0.41496117
123FGFR10.40841372
124MAP3K90.40609817
125CAMK1D0.40398628
126OXSR10.39899082
127MELK0.39505023
128BCKDK0.39263271
129GRK10.39218260
130MAPKAPK50.39212717
131PRKACA0.39041879
132STK110.38914189
133CSNK1A10.37374358
134LRRK20.35888009
135ERBB40.35444458
136PRKCI0.35179006
137PRKG10.33412505
138ATR0.32083349
139RAF10.31843422
140CAMK2A0.31056204
141CDK90.30366499
142PIM10.28900788
143GRK50.28889491
144EPHA40.27473866
145JAK30.27192699
146MST1R0.27098414

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.28875783
2Oxidative phosphorylation_Homo sapiens_hsa001904.35206247
3Parkinsons disease_Homo sapiens_hsa050123.68717783
4RNA polymerase_Homo sapiens_hsa030203.64701114
5Protein export_Homo sapiens_hsa030603.64400957
6Huntingtons disease_Homo sapiens_hsa050163.02043904
7DNA replication_Homo sapiens_hsa030302.93677667
8Homologous recombination_Homo sapiens_hsa034402.92165727
9Proteasome_Homo sapiens_hsa030502.84136891
10Alzheimers disease_Homo sapiens_hsa050102.78966780
11Mismatch repair_Homo sapiens_hsa034302.63136986
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.47951720
13Pyrimidine metabolism_Homo sapiens_hsa002402.38263479
14Base excision repair_Homo sapiens_hsa034102.23990382
15Spliceosome_Homo sapiens_hsa030402.09515177
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.07142737
17Nucleotide excision repair_Homo sapiens_hsa034202.02282837
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.97668737
19Basal transcription factors_Homo sapiens_hsa030221.82347539
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.80573770
21Purine metabolism_Homo sapiens_hsa002301.59731298
22Fanconi anemia pathway_Homo sapiens_hsa034601.59562986
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.53072743
24RNA degradation_Homo sapiens_hsa030181.52489716
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.51296055
26Cardiac muscle contraction_Homo sapiens_hsa042601.48777567
27Steroid biosynthesis_Homo sapiens_hsa001001.36333326
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.29691554
29Non-homologous end-joining_Homo sapiens_hsa034501.25350466
30RNA transport_Homo sapiens_hsa030131.17411495
31Butanoate metabolism_Homo sapiens_hsa006501.16953330
32Folate biosynthesis_Homo sapiens_hsa007901.15963502
33Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.14013443
34Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.08252247
35Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.06384333
36Cell cycle_Homo sapiens_hsa041101.06266747
37SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99055946
38Hedgehog signaling pathway_Homo sapiens_hsa043400.95410488
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.93517218
40Selenocompound metabolism_Homo sapiens_hsa004500.87092030
41Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.83446635
42Glutathione metabolism_Homo sapiens_hsa004800.81942012
43Sulfur relay system_Homo sapiens_hsa041220.79582179
44Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.79531409
45Allograft rejection_Homo sapiens_hsa053300.79228726
46Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78757625
47Caffeine metabolism_Homo sapiens_hsa002320.77636608
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.75028870
49Sulfur metabolism_Homo sapiens_hsa009200.73050305
50Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.72401004
51p53 signaling pathway_Homo sapiens_hsa041150.71318288
52Arachidonic acid metabolism_Homo sapiens_hsa005900.67436602
53Metabolic pathways_Homo sapiens_hsa011000.66811141
54One carbon pool by folate_Homo sapiens_hsa006700.65581819
55Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65398205
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64856705
57Tryptophan metabolism_Homo sapiens_hsa003800.63860445
58Retinol metabolism_Homo sapiens_hsa008300.62916953
59Systemic lupus erythematosus_Homo sapiens_hsa053220.62045686
60Hippo signaling pathway_Homo sapiens_hsa043900.61437266
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.60916949
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59489156
63Nitrogen metabolism_Homo sapiens_hsa009100.56871434
64Olfactory transduction_Homo sapiens_hsa047400.55133712
65Transcriptional misregulation in cancer_Homo sapiens_hsa052020.51953698
66Primary bile acid biosynthesis_Homo sapiens_hsa001200.51688511
67Asthma_Homo sapiens_hsa053100.50697805
68Maturity onset diabetes of the young_Homo sapiens_hsa049500.50196002
69Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.49608694
70Fatty acid elongation_Homo sapiens_hsa000620.49385569
71Fat digestion and absorption_Homo sapiens_hsa049750.48180735
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46837880
73Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46741268
74Rheumatoid arthritis_Homo sapiens_hsa053230.46579379
75Hematopoietic cell lineage_Homo sapiens_hsa046400.46134213
76TGF-beta signaling pathway_Homo sapiens_hsa043500.44931022
77Malaria_Homo sapiens_hsa051440.44040756
78Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43732978
79Taste transduction_Homo sapiens_hsa047420.43456160
80Sphingolipid metabolism_Homo sapiens_hsa006000.43251796
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.43180788
82Vitamin digestion and absorption_Homo sapiens_hsa049770.40974849
83Ether lipid metabolism_Homo sapiens_hsa005650.40860197
84NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40398267
85Autoimmune thyroid disease_Homo sapiens_hsa053200.39314888
86beta-Alanine metabolism_Homo sapiens_hsa004100.37577585
87Herpes simplex infection_Homo sapiens_hsa051680.37458670
88Fatty acid degradation_Homo sapiens_hsa000710.35648823
89Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34299309
90Intestinal immune network for IgA production_Homo sapiens_hsa046720.33278667
91Oocyte meiosis_Homo sapiens_hsa041140.33112399
92Peroxisome_Homo sapiens_hsa041460.33056072
93Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.32234933
94Epstein-Barr virus infection_Homo sapiens_hsa051690.31772029
95Regulation of autophagy_Homo sapiens_hsa041400.31701319
96Insulin secretion_Homo sapiens_hsa049110.31173124
97Serotonergic synapse_Homo sapiens_hsa047260.30098776
98Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.28485629
99Vibrio cholerae infection_Homo sapiens_hsa051100.28090092
100Morphine addiction_Homo sapiens_hsa050320.27916384
101mRNA surveillance pathway_Homo sapiens_hsa030150.27732019
102Cysteine and methionine metabolism_Homo sapiens_hsa002700.27043787
103Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.26678859
104Phototransduction_Homo sapiens_hsa047440.25089675
105Glutamatergic synapse_Homo sapiens_hsa047240.24978086
106Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.23783360
107RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.23062086
108Pentose phosphate pathway_Homo sapiens_hsa000300.22029165
109Other glycan degradation_Homo sapiens_hsa005110.21856952
110Thyroid cancer_Homo sapiens_hsa052160.21700278
111African trypanosomiasis_Homo sapiens_hsa051430.21541210
112Axon guidance_Homo sapiens_hsa043600.20756478
113Drug metabolism - other enzymes_Homo sapiens_hsa009830.20264110
114N-Glycan biosynthesis_Homo sapiens_hsa005100.20007281
115Circadian rhythm_Homo sapiens_hsa047100.19911235
116Propanoate metabolism_Homo sapiens_hsa006400.19650180
117Long-term depression_Homo sapiens_hsa047300.19328375
118Type I diabetes mellitus_Homo sapiens_hsa049400.18774089
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.17529292
120Linoleic acid metabolism_Homo sapiens_hsa005910.16086510
121Chemical carcinogenesis_Homo sapiens_hsa052040.15937676
122Collecting duct acid secretion_Homo sapiens_hsa049660.14250595
123Galactose metabolism_Homo sapiens_hsa000520.11188809
124Nicotine addiction_Homo sapiens_hsa050330.09647095
125Melanoma_Homo sapiens_hsa052180.09405810
126Graft-versus-host disease_Homo sapiens_hsa053320.08982413
127HTLV-I infection_Homo sapiens_hsa051660.08435252
128Basal cell carcinoma_Homo sapiens_hsa052170.07938826
129Pentose and glucuronate interconversions_Homo sapiens_hsa000400.06916511
130Pyruvate metabolism_Homo sapiens_hsa006200.06494823
131Wnt signaling pathway_Homo sapiens_hsa043100.06251084
132Measles_Homo sapiens_hsa051620.05722476
133Leishmaniasis_Homo sapiens_hsa051400.05527080
134Calcium signaling pathway_Homo sapiens_hsa040200.01950860
135Hepatitis B_Homo sapiens_hsa051610.01869154
136Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.01784024
137Ovarian steroidogenesis_Homo sapiens_hsa049130.01422659

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