SRGN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.39687485
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.05238915
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.05238915
4antigen processing and presentation of endogenous antigen (GO:0019883)4.96853302
5positive regulation by symbiont of host defense response (GO:0052509)4.52627700
6modulation by symbiont of host defense response (GO:0052031)4.52627700
7modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.52627700
8modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.52627700
9positive regulation by organism of defense response of other organism involved in symbiotic interact4.52627700
10modulation by symbiont of host immune response (GO:0052553)4.52627700
11negative regulation of cell killing (GO:0031342)4.49067561
12negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.49067561
13detection of other organism (GO:0098543)4.39052881
14positive regulation of gamma-delta T cell activation (GO:0046645)4.18420374
15macrophage activation involved in immune response (GO:0002281)4.08651547
16detection of bacterium (GO:0016045)4.02803598
17detection of molecule of bacterial origin (GO:0032490)3.99815169
18ribosomal small subunit assembly (GO:0000028)3.95024535
19regulation of tolerance induction (GO:0002643)3.89293954
20positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.88738494
21positive regulation of mast cell activation (GO:0033005)3.85014117
22neutrophil activation involved in immune response (GO:0002283)3.84503617
23positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.81704818
24detection of external biotic stimulus (GO:0098581)3.79310769
25myeloid dendritic cell activation (GO:0001773)3.79219668
26NIK/NF-kappaB signaling (GO:0038061)3.73652199
27regulation of T cell tolerance induction (GO:0002664)3.73503707
28regulation of mast cell degranulation (GO:0043304)3.68906977
29Arp2/3 complex-mediated actin nucleation (GO:0034314)3.65338109
30myeloid dendritic cell differentiation (GO:0043011)3.63873606
31positive regulation of B cell differentiation (GO:0045579)3.60744886
32microglial cell activation (GO:0001774)3.60730206
33defense response to protozoan (GO:0042832)3.56842142
34response to interferon-beta (GO:0035456)3.56333736
35negative regulation of growth of symbiont in host (GO:0044130)3.54905567
36negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.54905567
37modulation of growth of symbiont involved in interaction with host (GO:0044144)3.54905567
38regulation of growth of symbiont in host (GO:0044126)3.54905567
39positive regulation of mast cell degranulation (GO:0043306)3.54241981
40positive regulation of mast cell activation involved in immune response (GO:0033008)3.54241981
41regulation of interferon-beta biosynthetic process (GO:0045357)3.52727635
42regulation of mast cell activation involved in immune response (GO:0033006)3.50176910
43detection of biotic stimulus (GO:0009595)3.49314189
44antigen processing and presentation via MHC class Ib (GO:0002475)3.47134047
45regulation of mast cell activation (GO:0033003)3.44988776
46response to protozoan (GO:0001562)3.44822661
47regulation of B cell receptor signaling pathway (GO:0050855)3.44529380
48immunoglobulin mediated immune response (GO:0016064)3.44527101
49macrophage activation (GO:0042116)3.41939775
50positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.40641194
51negative regulation of T cell mediated immunity (GO:0002710)3.39823917
52leukocyte aggregation (GO:0070486)3.32794519
53negative regulation of lymphocyte mediated immunity (GO:0002707)3.28370960
54positive regulation of natural killer cell differentiation (GO:0032825)3.27988292
55respiratory burst (GO:0045730)3.27591246
56negative regulation of phagocytosis (GO:0050765)3.27256319
57regulation of T-helper 1 cell differentiation (GO:0045625)3.25776672
58regulation of interleukin-12 biosynthetic process (GO:0045075)3.24186697
59regulation of myeloid leukocyte mediated immunity (GO:0002886)3.24041283
60type I interferon signaling pathway (GO:0060337)3.22865602
61cellular response to type I interferon (GO:0071357)3.22865602
62response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.22364912
63response to host immune response (GO:0052572)3.22364912
64regulation of interleukin-8 biosynthetic process (GO:0045414)3.21998949
65cellular response to zinc ion (GO:0071294)3.21310331
66positive regulation of antigen processing and presentation (GO:0002579)3.21282936
67mast cell activation (GO:0045576)3.21055494
68response to type I interferon (GO:0034340)3.20829078
69dendritic cell differentiation (GO:0097028)3.17011325
70regulation of B cell differentiation (GO:0045577)3.12688340
71response to peptidoglycan (GO:0032494)3.12620991
72leukocyte degranulation (GO:0043299)3.11708967
73disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.10881438
74killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.10881438
75regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.10374315
76cellular response to interferon-beta (GO:0035458)3.09240046
77regulation of leukocyte degranulation (GO:0043300)3.09101824
78interferon-gamma production (GO:0032609)3.06404377
79response to interleukin-15 (GO:0070672)3.05751411
80T cell migration (GO:0072678)3.02776982
81B cell mediated immunity (GO:0019724)3.02544923
82positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.99557626
83negative regulation of leukocyte mediated immunity (GO:0002704)2.99411249
84neutrophil activation (GO:0042119)2.99023697
85positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.98794489
86response to muramyl dipeptide (GO:0032495)2.97323635
87regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.96363614
88positive regulation of macrophage differentiation (GO:0045651)2.95673288
89negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.93759337
90positive regulation of alpha-beta T cell proliferation (GO:0046641)2.93104423
91negative regulation of erythrocyte differentiation (GO:0045647)2.91646092
92neutrophil mediated immunity (GO:0002446)2.90929063
93negative thymic T cell selection (GO:0045060)2.90758541
94T-helper 1 type immune response (GO:0042088)2.90669667
95interferon-gamma-mediated signaling pathway (GO:0060333)2.90240797
96positive thymic T cell selection (GO:0045059)2.89811354
97response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.89645135
98response to host (GO:0075136)2.89645135
99response to host defenses (GO:0052200)2.89645135
100positive regulation of isotype switching (GO:0045830)2.88582500
101regulation of gamma-delta T cell differentiation (GO:0045586)2.88452374
102positive regulation of respiratory burst (GO:0060267)2.87980841
103response to fungus (GO:0009620)2.87966720
104cellular response to interleukin-15 (GO:0071350)2.87755400
105granulocyte activation (GO:0036230)2.87635652
106DNA deamination (GO:0045006)2.87140129
107regulation of RIG-I signaling pathway (GO:0039535)2.85540067
108regulation of gamma-delta T cell activation (GO:0046643)2.85406758
109germinal center formation (GO:0002467)2.85340347
110regulation of alpha-beta T cell proliferation (GO:0046640)2.83340834
111regulation of necroptotic process (GO:0060544)2.83335585
112regulation of antigen processing and presentation (GO:0002577)2.83082421
113negative regulation of interleukin-6 production (GO:0032715)2.82453957
114positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.82350152
115negative T cell selection (GO:0043383)2.80165066
116regulation of hypersensitivity (GO:0002883)2.79847913
117response to interferon-alpha (GO:0035455)2.79076176
118negative regulation of nitric oxide biosynthetic process (GO:0045019)2.78682232
119positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.78361801
120actin nucleation (GO:0045010)2.77308185
121regulation of natural killer cell differentiation (GO:0032823)2.76974790
122myeloid cell activation involved in immune response (GO:0002275)2.76279428
123regulation of interferon-alpha production (GO:0032647)2.75725425
124regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.75086656
125leukocyte mediated cytotoxicity (GO:0001909)2.72680618
126negative regulation of interleukin-12 production (GO:0032695)2.70052853
127CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.68840836
128necroptotic process (GO:0070266)2.68309324
129regulation of MHC class II biosynthetic process (GO:0045346)2.68152205
130viral transcription (GO:0019083)2.66909202
131positive regulation of B cell mediated immunity (GO:0002714)2.66830417
132positive regulation of immunoglobulin mediated immune response (GO:0002891)2.66830417
133angiogenesis involved in wound healing (GO:0060055)2.65892898
134positive regulation of T cell mediated cytotoxicity (GO:0001916)2.65148512
135negative regulation of viral genome replication (GO:0045071)2.63908419
136regulation of T cell mediated cytotoxicity (GO:0001914)2.63832980
137cellular extravasation (GO:0045123)2.63803340
138regulation of dendritic cell antigen processing and presentation (GO:0002604)2.63588212
139tolerance induction (GO:0002507)2.63167112
140myeloid leukocyte mediated immunity (GO:0002444)2.62217467
141definitive hemopoiesis (GO:0060216)2.61817807
142T cell homeostasis (GO:0043029)2.59662231
143positive regulation of interferon-alpha production (GO:0032727)2.59579801
144lipopolysaccharide-mediated signaling pathway (GO:0031663)2.58850071
145regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.58081171
146myeloid leukocyte activation (GO:0002274)2.57861022
147regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.56894047
148regulation of chemokine biosynthetic process (GO:0045073)2.56617152
149production of molecular mediator involved in inflammatory response (GO:0002532)2.56583289
150regulation of regulatory T cell differentiation (GO:0045589)2.54403311
151translational termination (GO:0006415)2.54229776
152B cell receptor signaling pathway (GO:0050853)2.54204179

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.97922171
2E2F7_22180533_ChIP-Seq_HELA_Human4.25155552
3BP1_19119308_ChIP-ChIP_Hs578T_Human4.24294371
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.08500890
5IRF8_21731497_ChIP-ChIP_J774_Mouse4.05207742
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.81287950
7* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.64421653
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.57905721
9* MYB_21317192_ChIP-Seq_ERMYB_Mouse3.18171866
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.08219560
11SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.07680924
12SCL_19346495_ChIP-Seq_HPC-7_Human3.03043641
13STAT4_19710469_ChIP-ChIP_TH1__Mouse2.87010122
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.79621721
15IRF8_27001747_Chip-Seq_BMDM_Mouse2.75957504
16SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.74031564
17* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.73531739
18STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.64044362
19NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.63644352
20RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.60886907
21SPI1_23547873_ChIP-Seq_NB4_Human2.46748495
22* MYB_26560356_Chip-Seq_TH2_Human2.35520037
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.34257214
24FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.32047647
25* VDR_21846776_ChIP-Seq_THP-1_Human2.20428131
26TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.12258913
27* VDR_24787735_ChIP-Seq_THP-1_Human2.06652938
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.06556090
29NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.05397238
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.04380110
31RUNX1_22412390_ChIP-Seq_EML_Mouse1.98771199
32* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.98315861
33* MAF_26560356_Chip-Seq_TH1_Human1.97560831
34* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.96147477
35MYB_26560356_Chip-Seq_TH1_Human1.95232044
36* VDR_24763502_ChIP-Seq_THP-1_Human1.94051151
37MYC_22102868_ChIP-Seq_BL_Human1.92021384
38RUNX_20019798_ChIP-Seq_JUKART_Human1.89141360
39FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.88941148
40NOTCH1_21737748_ChIP-Seq_TLL_Human1.87577225
41MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.83000184
42VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.76859136
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.75628557
44SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.74881809
45LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.74526660
46LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.70907019
47FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.66738202
48SMAD_19615063_ChIP-ChIP_OVARY_Human1.64460164
49ERG_20887958_ChIP-Seq_HPC-7_Mouse1.62906659
50GATA1_22025678_ChIP-Seq_K562_Human1.62118556
51UTX_26944678_Chip-Seq_JUKART_Human1.56531973
52* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.54442836
53* PU_27001747_Chip-Seq_BMDM_Mouse1.45269401
54GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.43536610
55E2F4_17652178_ChIP-ChIP_JURKAT_Human1.43490353
56SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.41320783
57VDR_23849224_ChIP-Seq_CD4+_Human1.41173533
58* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.38531363
59Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.37466639
60CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.35355262
61MYC_18555785_ChIP-Seq_MESCs_Mouse1.35168099
62GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.34074829
63SPI1_23127762_ChIP-Seq_K562_Human1.32454049
64GABP_17652178_ChIP-ChIP_JURKAT_Human1.32166799
65* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.29785416
66NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.29705594
67NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.29637267
68TCF7_22412390_ChIP-Seq_EML_Mouse1.28918305
69* GATA3_27048872_Chip-Seq_THYMUS_Human1.27037149
70KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.26858989
71E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.23932021
72STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.22054516
73* MAF_26560356_Chip-Seq_TH2_Human1.21906633
74EST1_17652178_ChIP-ChIP_JURKAT_Human1.20267173
75KDM2B_26808549_Chip-Seq_SUP-B15_Human1.19124236
76GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.16537235
77KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.15911856
78NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.15289545
79GATA1_19941826_ChIP-Seq_K562_Human1.14266462
80KDM2B_26808549_Chip-Seq_DND41_Human1.13384116
81TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.13371500
82ELK1_19687146_ChIP-ChIP_HELA_Human1.12568194
83FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.12416088
84* GATA3_26560356_Chip-Seq_TH2_Human1.10529633
85SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09524156
86PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08387656
87CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08355040
88PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.08002927
89* FOXP3_21729870_ChIP-Seq_TREG_Human1.07011938
90PU.1_20513432_ChIP-Seq_Bcells_Mouse1.06687715
91SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06606193
92* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05279765
93BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.04033707
94FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.03652674
95PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02255054
96GATA2_21666600_ChIP-Seq_HMVEC_Human0.98563247
97GATA2_19941826_ChIP-Seq_K562_Human0.96456342
98CIITA_25753668_ChIP-Seq_RAJI_Human0.94581011
99MYC_18358816_ChIP-ChIP_MESCs_Mouse0.93934133
100GATA1_19941827_ChIP-Seq_MEL_Mouse0.93043953
101VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.92492733
102CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.92176424
103PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89991344
104TFEB_21752829_ChIP-Seq_HELA_Human0.86207156
105RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86038626
106SRF_21415370_ChIP-Seq_HL-1_Mouse0.85854845
107ETS1_22383799_ChIP-Seq_G1ME_Mouse0.85370121
108JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.84811938
109STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.83816309
110ELK3_25401928_ChIP-Seq_HUVEC_Human0.83514743
111GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83229728
112* NCOR1_26117541_ChIP-Seq_K562_Human0.82789845
113RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.81600531
114XRN2_22483619_ChIP-Seq_HELA_Human0.81345799
115CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.80976559
116ETS1_20019798_ChIP-Seq_JURKAT_Human0.80585258
117E2F1_21310950_ChIP-Seq_MCF-7_Human0.80368262
118BCL6_27268052_Chip-Seq_Bcells_Human0.79761962
119FOXM1_23109430_ChIP-Seq_U2OS_Human0.79601832
120MYC_19030024_ChIP-ChIP_MESCs_Mouse0.79579965
121SPI1_20517297_ChIP-Seq_HL60_Human0.78467001
122KDM2B_26808549_Chip-Seq_JURKAT_Human0.77447886
123BCOR_27268052_Chip-Seq_Bcells_Human0.71332780
124TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.71199858

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.61023965
2MP0005671_abnormal_response_to3.73710731
3MP0009785_altered_susceptibility_to3.57800425
4MP0000685_abnormal_immune_system3.56668141
5MP0002148_abnormal_hypersensitivity_rea3.16129600
6MP0003436_decreased_susceptibility_to3.12587825
7MP0005000_abnormal_immune_tolerance2.88594042
8MP0003724_increased_susceptibility_to2.87526816
9MP0005025_abnormal_response_to2.86080924
10MP0001800_abnormal_humoral_immune2.71916341
11MP0005387_immune_system_phenotype2.71191560
12MP0001790_abnormal_immune_system2.71191560
13MP0002419_abnormal_innate_immunity2.64161002
14MP0003763_abnormal_thymus_physiology2.56405232
15MP0002452_abnormal_antigen_presenting2.55458968
16MP0003303_peritoneal_inflammation2.53591448
17MP0002723_abnormal_immune_serum2.51344920
18MP0002396_abnormal_hematopoietic_system2.50204113
19MP0002420_abnormal_adaptive_immunity2.44978514
20MP0001819_abnormal_immune_cell2.44202796
21MP0006082_CNS_inflammation2.33595329
22MP0002166_altered_tumor_susceptibility2.29950959
23MP0001873_stomach_inflammation2.26546650
24MP0001853_heart_inflammation2.20361277
25MP0005464_abnormal_platelet_physiology2.18051659
26MP0002398_abnormal_bone_marrow2.16868248
27MP0002405_respiratory_system_inflammati2.08796492
28MP0009333_abnormal_splenocyte_physiolog2.02974399
29MP0010155_abnormal_intestine_physiology2.02099273
30* MP0000716_abnormal_immune_system2.00803384
31MP0002006_tumorigenesis1.97495727
32MP0004510_myositis1.96203642
33MP0005397_hematopoietic_system_phenotyp1.91204654
34MP0001545_abnormal_hematopoietic_system1.91204654
35MP0001845_abnormal_inflammatory_respons1.81822954
36MP0002254_reproductive_system_inflammat1.78122773
37MP0002722_abnormal_immune_system1.74031276
38MP0000689_abnormal_spleen_morphology1.72227799
39* MP0002429_abnormal_blood_cell1.71728616
40MP0000465_gastrointestinal_hemorrhage1.70991395
41MP0005310_abnormal_salivary_gland1.67853040
42MP0004808_abnormal_hematopoietic_stem1.67458144
43MP0001533_abnormal_skeleton_physiology1.64426919
44MP0000490_abnormal_crypts_of1.57018468
45MP0003300_gastrointestinal_ulcer1.52329507
46MP0005174_abnormal_tail_pigmentation1.46432129
47MP0000343_altered_response_to1.44851943
48MP0004947_skin_inflammation1.44537947
49MP0000858_altered_metastatic_potential1.42837326
50MP0008469_abnormal_protein_level1.42670377
51MP0000569_abnormal_digit_pigmentation1.41599625
52MP0000703_abnormal_thymus_morphology1.39042160
53MP0008260_abnormal_autophagy1.36554236
54MP0003866_abnormal_defecation1.33738177
55MP0001348_abnormal_lacrimal_gland1.29883610
56MP0002138_abnormal_hepatobiliary_system1.26771298
57MP0003448_altered_tumor_morphology1.24619693
58MP0009764_decreased_sensitivity_to1.24002235
59MP0008057_abnormal_DNA_replication1.23892616
60MP0006054_spinal_hemorrhage1.18887035
61MP0005058_abnormal_lysosome_morphology1.12498377
62MP0005451_abnormal_body_composition1.09606000
63MP0003172_abnormal_lysosome_physiology1.08130232
64MP0009278_abnormal_bone_marrow1.07515982
65MP0004883_abnormal_blood_vessel1.03189352
66MP0005075_abnormal_melanosome_morpholog1.02581611
67MP0002933_joint_inflammation1.01020418
68MP0004381_abnormal_hair_follicle0.96489213
69MP0000604_amyloidosis0.96008585
70MP0001663_abnormal_digestive_system0.95845161
71MP0002877_abnormal_melanocyte_morpholog0.93583471
72MP0010307_abnormal_tumor_latency0.93021630
73MP0001851_eye_inflammation0.92679730
74MP0002998_abnormal_bone_remodeling0.92539290
75MP0002019_abnormal_tumor_incidence0.92493752
76MP0008007_abnormal_cellular_replicative0.91716975
77MP0003693_abnormal_embryo_hatching0.91527987
78MP0003075_altered_response_to0.88569434
79MP0008004_abnormal_stomach_pH0.88217602
80MP0002277_abnormal_respiratory_mucosa0.88060504
81MP0002095_abnormal_skin_pigmentation0.85800878
82MP0003806_abnormal_nucleotide_metabolis0.85370916
83MP0009840_abnormal_foam_cell0.84084936
84MP0009763_increased_sensitivity_to0.79992614
85MP0003045_fibrosis0.78394048
86MP0003191_abnormal_cellular_cholesterol0.78072217
87MP0010352_gastrointestinal_tract_polyps0.77457870
88MP0000249_abnormal_blood_vessel0.76771763
89MP0003690_abnormal_glial_cell0.76114549
90MP0010094_abnormal_chromosome_stability0.74763114
91MP0005167_abnormal_blood-brain_barrier0.74478806
92MP0003828_pulmonary_edema0.74320013
93MP0005076_abnormal_cell_differentiation0.74105107
94MP0003186_abnormal_redox_activity0.74099863
95MP0005390_skeleton_phenotype0.71924451
96MP0005166_decreased_susceptibility_to0.71595837
97MP0004782_abnormal_surfactant_physiolog0.70361612
98MP0002009_preneoplasia0.69114230
99MP0000015_abnormal_ear_pigmentation0.65688834
100MP0003077_abnormal_cell_cycle0.64439440
101MP0005164_abnormal_response_to0.64221612
102MP0003183_abnormal_peptide_metabolism0.63473471
103MP0003795_abnormal_bone_structure0.60594951
104MP0005319_abnormal_enzyme/_coenzyme0.60210514
105MP0002132_abnormal_respiratory_system0.59535952
106MP0003221_abnormal_cardiomyocyte_apopto0.58299606
107MP0000313_abnormal_cell_death0.57786384
108MP0008058_abnormal_DNA_repair0.57626533
109MP0001881_abnormal_mammary_gland0.55137352
110MP0002332_abnormal_exercise_endurance0.54651961
111MP0003656_abnormal_erythrocyte_physiolo0.54584893
112MP0000681_abnormal_thyroid_gland0.53064091
113MP0009765_abnormal_xenobiotic_induced0.52797565
114MP0001764_abnormal_homeostasis0.52293345
115MP0001986_abnormal_taste_sensitivity0.52239739
116MP0003091_abnormal_cell_migration0.52191493
117MP0008874_decreased_physiological_sensi0.50625098
118MP0008873_increased_physiological_sensi0.50501599
119MP0000371_diluted_coat_color0.50344717

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)5.15238778
2Myositis (HP:0100614)5.13324779
3Recurrent abscess formation (HP:0002722)5.00596805
4Elevated erythrocyte sedimentation rate (HP:0003565)4.73692178
5Recurrent bacterial skin infections (HP:0005406)4.59427247
6Thrombocytosis (HP:0001894)4.57264982
7Retrobulbar optic neuritis (HP:0100654)4.30105365
8Optic neuritis (HP:0100653)4.30105365
9Orchitis (HP:0100796)4.22816670
10Petechiae (HP:0000967)4.00608177
11Recurrent fungal infections (HP:0002841)3.94169831
12Chronic otitis media (HP:0000389)3.81037674
13Obstructive lung disease (HP:0006536)3.73098469
14Chronic obstructive pulmonary disease (HP:0006510)3.73098469
15IgM deficiency (HP:0002850)3.62638066
16Mediastinal lymphadenopathy (HP:0100721)3.53326056
17Vasculitis (HP:0002633)3.48393823
18Meningitis (HP:0001287)3.45766122
19Abnormality of macrophages (HP:0004311)3.40953338
20Recurrent skin infections (HP:0001581)3.40347363
21Recurrent bronchitis (HP:0002837)3.39660797
22Recurrent viral infections (HP:0004429)3.38867889
23Chronic mucocutaneous candidiasis (HP:0002728)3.35679799
24Recurrent cutaneous fungal infections (HP:0011370)3.35679799
25Stomatitis (HP:0010280)3.30149824
26Aplastic anemia (HP:0001915)3.29801688
27Abnormality of the prostate (HP:0008775)3.29198420
28Autoimmune thrombocytopenia (HP:0001973)3.27010238
29Abnormal delayed hypersensitivity skin test (HP:0002963)3.22440113
30Abnormality of T cell physiology (HP:0011840)3.21071020
31Pulmonary infiltrates (HP:0002113)3.20241408
32Amyloidosis (HP:0011034)3.17873169
33Recurrent gram-negative bacterial infections (HP:0005420)3.11746839
34Keratoconjunctivitis (HP:0001096)3.08040929
35Hemoptysis (HP:0002105)3.04344466
36Abnormality of T cells (HP:0002843)2.97753483
37Arterial thrombosis (HP:0004420)2.97434727
38Panhypogammaglobulinemia (HP:0003139)2.97028779
39Keratoconjunctivitis sicca (HP:0001097)2.91308686
40Prolonged bleeding time (HP:0003010)2.90425916
41Epistaxis (HP:0000421)2.86023169
42Increased IgM level (HP:0003496)2.79258438
43Abnormality of glycolipid metabolism (HP:0010969)2.78527989
44Abnormality of liposaccharide metabolism (HP:0010968)2.78527989
45Abnormality of glycosphingolipid metabolism (HP:0004343)2.78527989
46IgG deficiency (HP:0004315)2.77442633
47Hypergammaglobulinemia (HP:0010702)2.76133746
48Vacuolated lymphocytes (HP:0001922)2.76083945
49Purpura (HP:0000979)2.74429768
50Chest pain (HP:0100749)2.73722886
51Gingival bleeding (HP:0000225)2.73552705
52Abnormality of B cell number (HP:0010975)2.73109953
53B lymphocytopenia (HP:0010976)2.73109953
54Leukocytosis (HP:0001974)2.71012503
55Eosinophilia (HP:0001880)2.70343779
56Cellulitis (HP:0100658)2.69156473
57Nasal polyposis (HP:0100582)2.68387099
58Periodontitis (HP:0000704)2.67004977
59Abnormality of T cell number (HP:0011839)2.66518106
60Increased cerebral lipofuscin (HP:0011813)2.66040227
61Reduced antithrombin III activity (HP:0001976)2.64976401
62Encephalitis (HP:0002383)2.64584489
63Granulocytopenia (HP:0001913)2.60893393
64Abnormality of eosinophils (HP:0001879)2.59204600
65Gastrointestinal infarctions (HP:0005244)2.58003811
66Interstitial pulmonary disease (HP:0006530)2.57690352
67Spontaneous hematomas (HP:0007420)2.56753638
68Abnormal number of erythroid precursors (HP:0012131)2.56389079
69Abnormality of the nasal mucosa (HP:0000433)2.54463281
70Episodic fever (HP:0001954)2.54164235
71Gangrene (HP:0100758)2.52361112
72Agammaglobulinemia (HP:0004432)2.51459116
73Reticulocytopenia (HP:0001896)2.51121123
74Abnormality of cells of the erythroid lineage (HP:0012130)2.48228203
75Anorexia (HP:0002039)2.46963817
76Abnormality of cells of the lymphoid lineage (HP:0012140)2.46871492
77Inflammation of the large intestine (HP:0002037)2.44330348
78T lymphocytopenia (HP:0005403)2.42907141
79Colitis (HP:0002583)2.42767909
80Lymphopenia (HP:0001888)2.41299326
81Severe combined immunodeficiency (HP:0004430)2.40332517
82Autoimmune hemolytic anemia (HP:0001890)2.39651810
83Increased neuronal autofluorescent lipopigment (HP:0002074)2.38208043
84Gastrointestinal inflammation (HP:0004386)2.37306577
85Gingivitis (HP:0000230)2.34337597
86Pustule (HP:0200039)2.33071833
87Hepatosplenomegaly (HP:0001433)2.28498826
88Impaired platelet aggregation (HP:0003540)2.28307502
89Abnormal platelet function (HP:0011869)2.28307502
90Pulmonary embolism (HP:0002204)2.26841255
91Dysostosis multiplex (HP:0000943)2.26594755
92Osteomyelitis (HP:0002754)2.25828574
93Thrombophlebitis (HP:0004418)2.25796018
94Increased serum ferritin (HP:0003281)2.25022831
95Skin rash (HP:0000988)2.23081327
96Increased IgE level (HP:0003212)2.21595743
97Thyroiditis (HP:0100646)2.21128444
98Urticaria (HP:0001025)2.20577789
99Amaurosis fugax (HP:0100576)2.20228497
100Combined immunodeficiency (HP:0005387)2.18989101
101Hypochromic anemia (HP:0001931)2.18890411
102Systemic lupus erythematosus (HP:0002725)2.17871329
103Abnormality of the pleura (HP:0002103)2.17622174
104IgA deficiency (HP:0002720)2.17196017
105Hypochromic microcytic anemia (HP:0004840)2.15953174
106Type I transferrin isoform profile (HP:0003642)2.15556290
107Loss of speech (HP:0002371)2.14733340
108Gastrointestinal stroma tumor (HP:0100723)2.13504144
109Skin ulcer (HP:0200042)2.11741326
110Lymphoma (HP:0002665)2.10739872
111Sepsis (HP:0100806)2.10609591
112Abnormality of iron homeostasis (HP:0011031)2.09383913
113Basal ganglia calcification (HP:0002135)2.09318683
114Pulmonary fibrosis (HP:0002206)2.07844383
115Abnormality of the pericardium (HP:0001697)2.07808433
116Neutropenia (HP:0001875)2.07765676
117Recurrent pneumonia (HP:0006532)2.07431502
118Acute myeloid leukemia (HP:0004808)2.07413811
119Restrictive lung disease (HP:0002091)2.07222170
120Polyneuropathy (HP:0001271)2.06341768
121Joint swelling (HP:0001386)2.06315268
122Spondylolisthesis (HP:0003302)2.04867354
123Vertigo (HP:0002321)2.04128406
124Glomerulopathy (HP:0100820)2.03727104
125Chronic diarrhea (HP:0002028)2.02996056
126Arthralgia (HP:0002829)2.02541779
127Acute hepatic failure (HP:0006554)2.00019581

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.23795275
2MAP4K13.48204359
3MAP3K143.36295895
4IRAK42.94134460
5KIT2.73855657
6JAK32.73555970
7TBK12.61012761
8TEC2.54844364
9PIM22.44583346
10BLK2.43013233
11IKBKE2.36148630
12PRPF4B2.33213693
13TYK22.30741936
14BTK2.23881658
15ZAP702.15409942
16IKBKB2.10137694
17IRAK31.96543296
18NME21.81375014
19SYK1.73294056
20MAP3K121.58781228
21PIM11.50318509
22TAOK31.50237895
23ITK1.44935651
24FGR1.44731510
25STK161.38626791
26MAP2K31.38571675
27FLT31.36977082
28JAK11.35833277
29KDR1.34639116
30RIPK41.34136487
31CHUK1.30444318
32TGFBR21.29409860
33NLK1.23125536
34TGFBR11.21930660
35LCK1.21114162
36CSF1R1.19950911
37TAOK11.19175185
38MAP3K31.16295870
39GRK71.14648264
40MATK1.14528987
41TAOK21.14509380
42LYN1.13583681
43EIF2AK31.09437504
44HCK1.08782731
45MAP3K61.06051711
46MAP3K131.05877039
47IRAK21.01603309
48ACVR1B1.00763598
49STK101.00522473
50FES1.00120693
51MAP3K10.99766985
52MST40.98688526
53RPS6KA40.98344882
54ERN10.94899758
55EEF2K0.94274225
56JAK20.89985363
57CSK0.86619839
58EPHB10.86206262
59LRRK20.85261068
60GRK60.85041500
61VRK10.83945776
62SCYL20.82682444
63PDK10.80048925
64FGFR30.79331521
65MOS0.78436480
66CLK10.75783257
67WEE10.74171966
68NEK90.73941290
69EIF2AK10.73479150
70EIF2AK20.72819607
71TRPM70.71370278
72TNIK0.71046158
73MAP3K50.70611481
74KSR20.70605347
75YES10.68465237
76FGFR40.66916688
77MYLK0.66567359
78RPS6KB20.66335733
79STK40.61027891
80MKNK10.60074990
81IRAK10.59334771
82PDPK10.58905755
83MAPKAPK30.58395900
84HIPK20.58321953
85TIE10.57816978
86SIK30.57027814
87BRSK20.56468528
88EPHA30.55533410
89TESK20.54124781
90PAK40.52350011
91MAPKAPK20.51674480
92BMPR20.50706416
93FYN0.50581206
94MAPK70.50246083
95MAPK120.49444667
96MAPKAPK50.49008674
97MAP3K110.47892821
98MARK30.47561538
99MAPK40.46764619
100CDK40.46751603
101DYRK30.44584026
102CDK80.44483432
103PRKCD0.44286217
104PIK3CG0.43096107
105CDK190.42957909
106TNK20.42447376
107NEK20.42266092
108MAP3K20.42068694
109RPS6KA60.41802118
110STK240.41800484
111MARK20.41717579
112ATR0.41071490
113RAF10.40890689
114BMPR1B0.40338363
115TLK10.40337912
116ABL20.39936260
117RPS6KA50.39835460
118ABL10.38533683
119ADRBK20.38362537
120RPS6KC10.37678879
121RPS6KL10.37678879
122CDK60.36982831
123TESK10.36915907
124PRKCQ0.35762527
125PRKG20.35330739
126SIK20.35209579
127MAP2K60.33887483
128DAPK20.33570830
129MAP2K20.29142953
130CAMKK20.29039920
131MAP2K40.26254576
132RET0.24189303
133EGFR0.23170707
134MAPK30.22646512
135WNK10.22542887
136INSR0.20809663
137CDC42BPA0.17894181

Predicted pathways (KEGG)

RankGene SetZ-score
1Allograft rejection_Homo sapiens_hsa053303.26421566
2Primary immunodeficiency_Homo sapiens_hsa053402.85028376
3Intestinal immune network for IgA production_Homo sapiens_hsa046722.83185899
4Leishmaniasis_Homo sapiens_hsa051402.82618585
5Asthma_Homo sapiens_hsa053102.74993656
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.56877712
7Graft-versus-host disease_Homo sapiens_hsa053322.49712897
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.47631617
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.44449321
10Antigen processing and presentation_Homo sapiens_hsa046122.19587680
11Autoimmune thyroid disease_Homo sapiens_hsa053202.17934878
12Measles_Homo sapiens_hsa051622.12370299
13DNA replication_Homo sapiens_hsa030302.07533956
14Ribosome_Homo sapiens_hsa030102.06727382
15RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.02087058
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.95812496
17Hematopoietic cell lineage_Homo sapiens_hsa046401.93367694
18Osteoclast differentiation_Homo sapiens_hsa043801.89399245
19Legionellosis_Homo sapiens_hsa051341.88770889
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.76146479
21Herpes simplex infection_Homo sapiens_hsa051681.70631002
22Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.66649565
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.63628731
24Pertussis_Homo sapiens_hsa051331.59310224
25Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.54352597
26Malaria_Homo sapiens_hsa051441.51793904
27B cell receptor signaling pathway_Homo sapiens_hsa046621.51160180
28Toxoplasmosis_Homo sapiens_hsa051451.43146155
29Staphylococcus aureus infection_Homo sapiens_hsa051501.42885423
30Other glycan degradation_Homo sapiens_hsa005111.36737555
31Tuberculosis_Homo sapiens_hsa051521.35010681
32Influenza A_Homo sapiens_hsa051641.33664392
33Type I diabetes mellitus_Homo sapiens_hsa049401.32984387
34TNF signaling pathway_Homo sapiens_hsa046681.31542483
35Apoptosis_Homo sapiens_hsa042101.28103069
36Base excision repair_Homo sapiens_hsa034101.28069537
37Shigellosis_Homo sapiens_hsa051311.26653789
38T cell receptor signaling pathway_Homo sapiens_hsa046601.24920051
39Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.21573863
40Mismatch repair_Homo sapiens_hsa034301.20537311
41Salmonella infection_Homo sapiens_hsa051321.20315340
42Homologous recombination_Homo sapiens_hsa034401.17683345
43Proteasome_Homo sapiens_hsa030501.14430158
44Rheumatoid arthritis_Homo sapiens_hsa053231.12536412
45Chemokine signaling pathway_Homo sapiens_hsa040621.07500777
46Hepatitis B_Homo sapiens_hsa051611.06700420
47Viral myocarditis_Homo sapiens_hsa054161.05279389
48Glycosaminoglycan degradation_Homo sapiens_hsa005311.04708083
49Transcriptional misregulation in cancer_Homo sapiens_hsa052021.04664581
50African trypanosomiasis_Homo sapiens_hsa051430.99054280
51Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.95426480
52Acute myeloid leukemia_Homo sapiens_hsa052210.94888836
53Protein export_Homo sapiens_hsa030600.94541035
54Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.92872753
55Non-small cell lung cancer_Homo sapiens_hsa052230.91098410
56Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.89372558
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.88298824
58Lysosome_Homo sapiens_hsa041420.85572563
59Epstein-Barr virus infection_Homo sapiens_hsa051690.85440415
60p53 signaling pathway_Homo sapiens_hsa041150.80358549
61Leukocyte transendothelial migration_Homo sapiens_hsa046700.80116744
62Platelet activation_Homo sapiens_hsa046110.78856144
63Nucleotide excision repair_Homo sapiens_hsa034200.77840953
64Spliceosome_Homo sapiens_hsa030400.75332812
65VEGF signaling pathway_Homo sapiens_hsa043700.74328291
66Non-homologous end-joining_Homo sapiens_hsa034500.72750646
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72423917
68Pyrimidine metabolism_Homo sapiens_hsa002400.71907406
69Sphingolipid signaling pathway_Homo sapiens_hsa040710.66158524
70Phagosome_Homo sapiens_hsa041450.64934362
71AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64158609
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.63686295
73Small cell lung cancer_Homo sapiens_hsa052220.61485678
74N-Glycan biosynthesis_Homo sapiens_hsa005100.61205640
75Chronic myeloid leukemia_Homo sapiens_hsa052200.61105731
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60259329
77Viral carcinogenesis_Homo sapiens_hsa052030.60211709
78Hepatitis C_Homo sapiens_hsa051600.59998416
79HTLV-I infection_Homo sapiens_hsa051660.59592605
80RNA polymerase_Homo sapiens_hsa030200.58603289
81Pentose phosphate pathway_Homo sapiens_hsa000300.57116196
82Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56515497
83Renal cell carcinoma_Homo sapiens_hsa052110.56338532
84Caffeine metabolism_Homo sapiens_hsa002320.55132492
85Systemic lupus erythematosus_Homo sapiens_hsa053220.55096428
86RNA degradation_Homo sapiens_hsa030180.52878472
87Dorso-ventral axis formation_Homo sapiens_hsa043200.51475327
88Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.50271036
89Pancreatic cancer_Homo sapiens_hsa052120.49906160
90Renin-angiotensin system_Homo sapiens_hsa046140.47445209
91Cell cycle_Homo sapiens_hsa041100.46674156
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46497574
93Adipocytokine signaling pathway_Homo sapiens_hsa049200.44035558
94Amoebiasis_Homo sapiens_hsa051460.43384443
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.40696818
96Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40051843
97Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39969184
98Prolactin signaling pathway_Homo sapiens_hsa049170.39481561
99Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.39202697
100Fanconi anemia pathway_Homo sapiens_hsa034600.39131578
101Endocytosis_Homo sapiens_hsa041440.37812919
102FoxO signaling pathway_Homo sapiens_hsa040680.36444864
103Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.36255551
104Phospholipase D signaling pathway_Homo sapiens_hsa040720.35853955
105Carbohydrate digestion and absorption_Homo sapiens_hsa049730.35054850
106Arachidonic acid metabolism_Homo sapiens_hsa005900.34628734
107Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33869264
108Neurotrophin signaling pathway_Homo sapiens_hsa047220.32961355
109GnRH signaling pathway_Homo sapiens_hsa049120.32472000
110Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.31922680
111Bladder cancer_Homo sapiens_hsa052190.30700584
112Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.29894223
113Choline metabolism in cancer_Homo sapiens_hsa052310.28692744
114Type II diabetes mellitus_Homo sapiens_hsa049300.27636446
115Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27537921
116MAPK signaling pathway_Homo sapiens_hsa040100.26093527
117HIF-1 signaling pathway_Homo sapiens_hsa040660.26003644
118Galactose metabolism_Homo sapiens_hsa000520.25610915
119Insulin resistance_Homo sapiens_hsa049310.23260979
120One carbon pool by folate_Homo sapiens_hsa006700.22873154
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.22793020
122Phosphatidylinositol signaling system_Homo sapiens_hsa040700.21941343
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.20583827
124Regulation of autophagy_Homo sapiens_hsa041400.19483695
125Alcoholism_Homo sapiens_hsa050340.17667474
126mTOR signaling pathway_Homo sapiens_hsa041500.16525551
127Notch signaling pathway_Homo sapiens_hsa043300.15995201
128Complement and coagulation cascades_Homo sapiens_hsa046100.15379976
129Collecting duct acid secretion_Homo sapiens_hsa049660.15264646
130Colorectal cancer_Homo sapiens_hsa052100.14689439

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