SRMS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sulfation (GO:0051923)7.00040877
2negative regulation of protein autophosphorylation (GO:0031953)5.40168106
3fusion of sperm to egg plasma membrane (GO:0007342)5.38353737
4desmosome organization (GO:0002934)5.37531853
5establishment of protein localization to Golgi (GO:0072600)5.29488417
6Golgi transport vesicle coating (GO:0048200)5.07823199
7COPI coating of Golgi vesicle (GO:0048205)5.07823199
8cytoskeletal anchoring at plasma membrane (GO:0007016)4.93870072
9venous blood vessel morphogenesis (GO:0048845)4.93576130
10negative regulation of nitric-oxide synthase activity (GO:0051001)4.90819076
11citrulline biosynthetic process (GO:0019240)4.89622555
12cell migration involved in heart development (GO:0060973)4.85101749
13regulation of cholesterol homeostasis (GO:2000188)4.79805233
14negative regulation of cell size (GO:0045792)4.76129594
15biotin metabolic process (GO:0006768)4.71810139
16plasma membrane fusion (GO:0045026)4.70059331
17molting cycle (GO:0042303)4.68250791
18hair cycle (GO:0042633)4.68250791
19activation of Rac GTPase activity (GO:0032863)4.60874124
20long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)4.58306344
21branching involved in prostate gland morphogenesis (GO:0060442)4.56688607
22antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.51238883
23negative regulation of sterol transport (GO:0032372)4.50917370
24negative regulation of cholesterol transport (GO:0032375)4.50917370
25endothelial cell chemotaxis (GO:0035767)4.44889686
26proline biosynthetic process (GO:0006561)4.21963012
27regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)4.18348850
28regulation of receptor binding (GO:1900120)4.16418845
29intestinal epithelial cell development (GO:0060576)4.15386523
30L-phenylalanine catabolic process (GO:0006559)4.15263354
31erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.15263354
32positive regulation of Cdc42 GTPase activity (GO:0043089)4.14133327
33peptidyl-glutamic acid carboxylation (GO:0017187)4.11664315
34protein carboxylation (GO:0018214)4.11664315
35fatty-acyl-CoA biosynthetic process (GO:0046949)4.06627277
36hemidesmosome assembly (GO:0031581)3.96457978
37regulation of water loss via skin (GO:0033561)3.95803721
38negative regulation of fibrinolysis (GO:0051918)3.95645345
39retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.92401799
40pantothenate metabolic process (GO:0015939)3.92154451
41maternal placenta development (GO:0001893)3.87917324
42carnitine shuttle (GO:0006853)3.87029544
43epithelial cell differentiation involved in prostate gland development (GO:0060742)3.85069479
44aromatic amino acid family catabolic process (GO:0009074)3.84323500
45bile acid biosynthetic process (GO:0006699)3.82977471
46fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.82936504
47semaphorin-plexin signaling pathway (GO:0071526)3.78268460
48regulation of fibrinolysis (GO:0051917)3.76177973
49phospholipid translocation (GO:0045332)3.72073006
50lipid translocation (GO:0034204)3.72073006
51L-phenylalanine metabolic process (GO:0006558)3.71459541
52erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.71459541
53cell-cell junction maintenance (GO:0045217)3.69737377
54ear development (GO:0043583)3.69149749
55epithelial cell maturation (GO:0002070)3.67403715
56antigen processing and presentation of endogenous antigen (GO:0019883)3.67355119
57prostate gland epithelium morphogenesis (GO:0060740)3.66251295
58myelin maintenance (GO:0043217)3.64334672
59regulation of protein activation cascade (GO:2000257)3.62001761
60negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)3.61883327
61regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.61058921
62positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.60515934
63negative regulation of erythrocyte differentiation (GO:0045647)3.58061279
64triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.57948450
65apoptotic process involved in morphogenesis (GO:0060561)3.57253241
66complement activation, alternative pathway (GO:0006957)3.56612600
67establishment of skin barrier (GO:0061436)3.56152541
68regulation of cholesterol biosynthetic process (GO:0045540)3.54767347
69positive regulation of histone deacetylation (GO:0031065)3.53403261
70kynurenine metabolic process (GO:0070189)3.52737665
71antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.52719555
72antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.52719555
73tryptophan catabolic process (GO:0006569)3.48126520
74indole-containing compound catabolic process (GO:0042436)3.48126520
75indolalkylamine catabolic process (GO:0046218)3.48126520
76regulation of complement activation (GO:0030449)3.46197263
77phosphate ion transport (GO:0006817)3.44420139
78urea metabolic process (GO:0019627)3.42496104
79urea cycle (GO:0000050)3.42496104
80purine ribonucleotide transport (GO:0015868)3.39734920
81alpha-linolenic acid metabolic process (GO:0036109)3.39159911
82regulation of fatty acid beta-oxidation (GO:0031998)3.38152526
83acetyl-CoA metabolic process (GO:0006084)3.36463881
84regulation of RNA export from nucleus (GO:0046831)3.35470525
85multicellular organismal water homeostasis (GO:0050891)3.33707672
86negative regulation of protein activation cascade (GO:2000258)3.33335078
87complement activation, classical pathway (GO:0006958)3.30761859
88histone H2A acetylation (GO:0043968)3.30623457
89acyl-CoA biosynthetic process (GO:0071616)3.30232559
90thioester biosynthetic process (GO:0035384)3.30232559
91antigen processing and presentation via MHC class Ib (GO:0002475)3.28391921
92sulfur amino acid catabolic process (GO:0000098)3.26900056
93bundle of His cell to Purkinje myocyte communication (GO:0086069)3.23816652
94sensory perception of taste (GO:0050909)3.22956428
95phospholipid efflux (GO:0033700)3.22441067
96high-density lipoprotein particle remodeling (GO:0034375)3.22310003
97glyoxylate metabolic process (GO:0046487)3.22234232
98long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.21645147
99spliceosomal tri-snRNP complex assembly (GO:0000244)3.20745391
100heme transport (GO:0015886)3.19188247
101proline metabolic process (GO:0006560)3.18287151
102nitrogen cycle metabolic process (GO:0071941)3.16127725
103negative regulation of cell fate commitment (GO:0010454)3.15794333
104epithelial cell-cell adhesion (GO:0090136)3.14099095
105complement activation (GO:0006956)3.10717444
106citrulline metabolic process (GO:0000052)3.10668453
107purine nucleotide transport (GO:0015865)3.10566791
108bile acid metabolic process (GO:0008206)3.09708634
109tryptophan metabolic process (GO:0006568)3.09519394
110establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)3.09386859
111very long-chain fatty acid metabolic process (GO:0000038)3.08304167
112negative regulation of monooxygenase activity (GO:0032769)3.07887044
113cytoplasmic mRNA processing body assembly (GO:0033962)3.07319040
114protein retention in ER lumen (GO:0006621)3.05256545
115regulation of NFAT protein import into nucleus (GO:0051532)3.04884858
116lung epithelial cell differentiation (GO:0060487)3.03125896
117cell junction maintenance (GO:0034331)3.01925465
118oxaloacetate metabolic process (GO:0006107)3.01678693
119positive regulation of systemic arterial blood pressure (GO:0003084)3.01078745
120regulation of cholesterol storage (GO:0010885)2.99223329
121lung cell differentiation (GO:0060479)2.98142328
122fatty acid elongation (GO:0030497)2.97624375
123phosphate ion transmembrane transport (GO:0035435)2.97592352
124regulation of triglyceride catabolic process (GO:0010896)2.96325495
125regulation of glucose import in response to insulin stimulus (GO:2001273)2.96200206
126positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.94870914
127establishment or maintenance of bipolar cell polarity (GO:0061245)2.94463519
128establishment or maintenance of apical/basal cell polarity (GO:0035088)2.94463519
129protein activation cascade (GO:0072376)2.93304958
130negative regulation of complement activation (GO:0045916)2.93107135
131negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.93093050
132ribosomal small subunit assembly (GO:0000028)2.91860288
133fibrinolysis (GO:0042730)2.90923595
134opsonization (GO:0008228)2.90749335
135adherens junction assembly (GO:0034333)2.89972974
136mitochondrion localization (GO:0051646)2.89333040
137short-chain fatty acid metabolic process (GO:0046459)2.87931157
138regulation of nucleobase-containing compound transport (GO:0032239)2.87915612
139glucocorticoid receptor signaling pathway (GO:0042921)2.86833185
140maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.85987712
141histone H3-K36 demethylation (GO:0070544)2.85200616
142carnitine transmembrane transport (GO:1902603)2.84656333
143plasma lipoprotein particle clearance (GO:0034381)2.82568987
144intracellular estrogen receptor signaling pathway (GO:0030520)2.81856459
145ethanol oxidation (GO:0006069)2.81069988
146homocysteine metabolic process (GO:0050667)2.80229067
147regulation of viral release from host cell (GO:1902186)2.79870436
148positive regulation of cellular amine metabolic process (GO:0033240)2.79693583
149glandular epithelial cell differentiation (GO:0002067)2.78439541
150* peptidyl-tyrosine autophosphorylation (GO:0038083)2.78097307
151vitamin D metabolic process (GO:0042359)2.77964011
152water homeostasis (GO:0030104)2.77700661
153apical protein localization (GO:0045176)2.76951192
154focal adhesion assembly (GO:0048041)2.76108091
155cell-substrate adherens junction assembly (GO:0007045)2.76108091
156response to testosterone (GO:0033574)2.76079747
157establishment of apical/basal cell polarity (GO:0035089)2.74391080
158response to lipoprotein particle (GO:0055094)2.74337731
159branching involved in mammary gland duct morphogenesis (GO:0060444)2.73971514
160fatty acid beta-oxidation (GO:0006635)2.71998149
161vesicle targeting (GO:0006903)2.71895700
162positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.71718410
163fatty acid transmembrane transport (GO:1902001)2.71458692
164cysteine metabolic process (GO:0006534)2.71231570
165regulation of mammary gland epithelial cell proliferation (GO:0033599)2.71110322
166negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.69588406
167positive regulation of protein deacetylation (GO:0090312)2.68470074
168amino-acid betaine metabolic process (GO:0006577)2.68094875
169mitochondrion degradation (GO:0000422)2.66468786
170positive regulation of epidermal cell differentiation (GO:0045606)2.64406760
171negative regulation of viral release from host cell (GO:1902187)2.64343928
172regulation of humoral immune response (GO:0002920)2.64291161
173regulation of hypersensitivity (GO:0002883)2.64242981
174fatty acid catabolic process (GO:0009062)2.63995466
175artery development (GO:0060840)2.63264088
176positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.62784315
177pharyngeal system development (GO:0060037)2.62768957
178corticosteroid receptor signaling pathway (GO:0031958)2.61387089
179branching involved in salivary gland morphogenesis (GO:0060445)2.61041111
180positive regulation of CREB transcription factor activity (GO:0032793)2.60729462
181regulation of actin nucleation (GO:0051125)2.59968683
182triglyceride homeostasis (GO:0070328)2.59666081
183acylglycerol homeostasis (GO:0055090)2.59666081
184fatty-acyl-CoA metabolic process (GO:0035337)2.59558128
185positive thymic T cell selection (GO:0045059)2.59109258
186calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.58761127
187blood coagulation, intrinsic pathway (GO:0007597)2.58758291
188negative regulation of fatty acid biosynthetic process (GO:0045717)2.58733927
189cell-substrate junction assembly (GO:0007044)2.58582524
190glutamate metabolic process (GO:0006536)2.58468007
191ethanol metabolic process (GO:0006067)2.58263237
192trivalent inorganic anion homeostasis (GO:0072506)2.58036577
193adhesion of symbiont to host cell (GO:0044650)2.57985672
194virion attachment to host cell (GO:0019062)2.57985672
195response to phenylpropanoid (GO:0080184)2.56884167
196fatty acid oxidation (GO:0019395)2.56522403

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.10826956
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.36270328
3ZNF263_19887448_ChIP-Seq_K562_Human4.87703281
4RXR_22158963_ChIP-Seq_LIVER_Mouse3.80264996
5PPARA_22158963_ChIP-Seq_LIVER_Mouse3.66978880
6ESR2_21235772_ChIP-Seq_MCF-7_Human3.09839055
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.98416556
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.97340398
9LXR_22158963_ChIP-Seq_LIVER_Mouse2.96165090
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.89941382
11EGR1_23403033_ChIP-Seq_LIVER_Mouse2.66722358
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.63520323
13FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.57513607
14EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.41195907
15TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.27543641
16KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.21156376
17GATA1_22025678_ChIP-Seq_K562_Human2.18333418
18RUNX_20019798_ChIP-Seq_JUKART_Human2.13686391
19TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.09043082
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.02172166
21ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.91926804
22NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.91380429
23TET1_21451524_ChIP-Seq_MESCs_Mouse1.90136560
24* P68_20966046_ChIP-Seq_HELA_Human1.84961084
25KDM2B_26808549_Chip-Seq_K562_Human1.79781530
26LXR_22292898_ChIP-Seq_THP-1_Human1.76806679
27* SMC4_20622854_ChIP-Seq_HELA_Human1.76148334
28GATA2_21666600_ChIP-Seq_HMVEC_Human1.74489090
29CREB1_26743006_Chip-Seq_LNCaP_Human1.74384638
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.72093907
31ESR1_20079471_ChIP-ChIP_T-47D_Human1.71899504
32SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.71353578
33DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.68233517
34CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.67685958
35IRF8_21731497_ChIP-ChIP_J774_Mouse1.65170590
36CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.64992417
37P63_26484246_Chip-Seq_KERATINOCYTES_Human1.63016807
38ZFP281_18757296_ChIP-ChIP_E14_Mouse1.59984803
39PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.59388035
40* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.54525854
41CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.53693397
42STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.51258534
43CTCF_27219007_Chip-Seq_ERYTHROID_Human1.51166527
44SOX9_24532713_ChIP-Seq_HFSC_Mouse1.50609967
45ATF3_27146783_Chip-Seq_COLON_Human1.46713237
46* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.43919175
47NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.43097481
48ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.41078544
49CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.39213697
50BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.36265931
51CHD1_26751641_Chip-Seq_LNCaP_Human1.35094513
52STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.33457287
53ELF1_20517297_ChIP-Seq_JURKAT_Human1.32780410
54RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.32615309
55SOX2_27498859_Chip-Seq_STOMACH_Mouse1.30703634
56KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.29898453
57VDR_21846776_ChIP-Seq_THP-1_Human1.29746571
58CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.29151574
59SCL_19346495_ChIP-Seq_HPC-7_Human1.28064749
60RARB_24833708_ChIP-Seq_LIVER_Mouse1.27916569
61ESR1_21235772_ChIP-Seq_MCF-7_Human1.27667237
62HIF1A_21447827_ChIP-Seq_MCF-7_Human1.26156065
63THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.25920928
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.25565606
65ELK3_25401928_ChIP-Seq_HUVEC_Human1.24889059
66FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.24754778
67NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.24293083
68UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.22178845
69GATA6_25053715_ChIP-Seq_YYC3_Human1.21753008
70ESR1_15608294_ChIP-ChIP_MCF-7_Human1.20218811
71SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20037880
72KDM5A_27292631_Chip-Seq_BREAST_Human1.18321822
73EGR1_19032775_ChIP-ChIP_M12_Human1.16794621
74ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.15458019
75TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.14635140
76PKCTHETA_26484144_Chip-Seq_BREAST_Human1.14524414
77HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.13783047
78WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.13299881
79IRF8_27001747_Chip-Seq_BMDM_Mouse1.12965879
80SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.11963243
81* RUNX1_27514584_Chip-Seq_MCF-7_Human1.11329715
82FOXO3_23340844_ChIP-Seq_DLD1_Human1.11174440
83* KDM2B_26808549_Chip-Seq_DND41_Human1.10834539
84P300_27058665_Chip-Seq_ZR-75-30cells_Human1.10551614
85ZFP281_27345836_Chip-Seq_ESCs_Mouse1.09681841
86KDM2B_26808549_Chip-Seq_JURKAT_Human1.08454257
87* CTCF_27219007_Chip-Seq_Bcells_Human1.08292607
88DROSHA_22980978_ChIP-Seq_HELA_Human1.07943618
89RAD21_21589869_ChIP-Seq_MESCs_Mouse1.07107345
90RARA_24833708_ChIP-Seq_LIVER_Mouse1.07056996
91MYC_22102868_ChIP-Seq_BL_Human1.06820490
92MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.06617204
93MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.06307064
94DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06227220
95CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.05702847
96FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05531890
97NCOR1_26117541_ChIP-Seq_K562_Human1.05525263
98E2F1_20622854_ChIP-Seq_HELA_Human1.05197109
99PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.04748457
100KLF5_25053715_ChIP-Seq_YYC3_Human1.04538372
101IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.04194517
102DNAJC2_21179169_ChIP-ChIP_NT2_Human1.03705111
103STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.03030935
104CDX2_20551321_ChIP-Seq_CACO-2_Human1.02222197
105TCF7_22412390_ChIP-Seq_EML_Mouse1.00294967
106PHF8_20622854_ChIP-Seq_HELA_Human0.99748968
107SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.99495894
108SRY_22984422_ChIP-ChIP_TESTIS_Rat0.98607172
109* MAF_26560356_Chip-Seq_TH1_Human0.98259528
110CTCF_20526341_ChIP-Seq_ESCs_Human0.98002938
111TET1_21490601_ChIP-Seq_MESCs_Mouse0.97872009
112ZFX_18555785_ChIP-Seq_MESCs_Mouse0.97607169
113SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97270120
114GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97239541
115* BCL6_27268052_Chip-Seq_Bcells_Human0.97145135
116VDR_24763502_ChIP-Seq_THP-1_Human0.96833059
117ETS1_21867929_ChIP-Seq_TH2_Mouse0.96563827
118AHR_22903824_ChIP-Seq_MCF-7_Human0.96369859
119BRD4_27068464_Chip-Seq_AML-cells_Mouse0.96291315
120GATA2_19941826_ChIP-Seq_K562_Human0.95839287
121E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.95300405
122CLOCK_20551151_ChIP-Seq_293T_Human0.94544619
123STAT4_19710469_ChIP-ChIP_TH1__Mouse0.94144812
124UTX_26944678_Chip-Seq_JUKART_Human0.93621468
125TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93305856
126TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.93247261
127MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.92943684
128CTCF_21964334_Chip-Seq_Bcells_Human0.92925333
129NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.92654173
130KDM2B_26808549_Chip-Seq_SUP-B15_Human0.92599637
131KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.92420064
132MYB_21317192_ChIP-Seq_ERMYB_Mouse0.91538795
133RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.91292230
134TP53_22127205_ChIP-Seq_IMR90_Human0.90678554
135FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.90130880
136TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89541143
137GATA1_19941826_ChIP-Seq_K562_Human0.88954066
138SA1_27219007_Chip-Seq_Bcells_Human0.88747303
139* BCOR_27268052_Chip-Seq_Bcells_Human0.88004669
140CTCF_21964334_ChIP-Seq_BJAB-B_Human0.87651545
141RACK7_27058665_Chip-Seq_MCF-7_Human0.87339258
142SA1_27219007_Chip-Seq_ERYTHROID_Human0.86426903
143SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.86104478
144STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.85973271
145GATA4_25053715_ChIP-Seq_YYC3_Human0.85347784
146P53_21459846_ChIP-Seq_SAOS-2_Human0.85111279
147FOXA2_19822575_ChIP-Seq_HepG2_Human0.83958672
148RARG_19884340_ChIP-ChIP_MEFs_Mouse0.83862931
149* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.83599119
150PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.83066384
151EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.81963460
152KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.81620702
153ARNT_22903824_ChIP-Seq_MCF-7_Human0.80389420
154GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.80267653
155SOX2_20726797_ChIP-Seq_SW620_Human0.79607559
156STAT3_1855785_ChIP-Seq_MESCs_Mouse0.78436116
157TRIM28_21343339_ChIP-Seq_HEK293_Human0.78346721
158TP63_22573176_ChIP-Seq_HFKS_Human0.78322827
159* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.77858958
160SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.77728243

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000537_abnormal_urethra_morphology4.13478593
2MP0002139_abnormal_hepatobiliary_system4.04649439
3MP0002254_reproductive_system_inflammat3.96222542
4MP0005360_urolithiasis3.87637169
5MP0005085_abnormal_gallbladder_physiolo3.86803635
6MP0002796_impaired_skin_barrier3.78855222
7MP0005365_abnormal_bile_salt3.42205637
8MP0004858_abnormal_nervous_system3.20051319
9MP0010234_abnormal_vibrissa_follicle3.16920013
10MP0005310_abnormal_salivary_gland3.06773005
11MP0001873_stomach_inflammation2.87482529
12MP0005645_abnormal_hypothalamus_physiol2.82215251
13MP0004264_abnormal_extraembryonic_tissu2.65108584
14MP0009840_abnormal_foam_cell2.56239934
15MP0005076_abnormal_cell_differentiation2.53769849
16MP0003252_abnormal_bile_duct2.41781006
17MP0005410_abnormal_fertilization2.39246204
18MP0008875_abnormal_xenobiotic_pharmacok2.36978781
19MP0008961_abnormal_basal_metabolism2.33334592
20MP0000383_abnormal_hair_follicle2.33246866
21MP0000678_abnormal_parathyroid_gland2.27922264
22MP0002138_abnormal_hepatobiliary_system2.23932418
23MP0001348_abnormal_lacrimal_gland2.22012045
24MP0000685_abnormal_immune_system2.15821598
25MP0003315_abnormal_perineum_morphology2.11818285
26MP0005501_abnormal_skin_physiology2.11149464
27MP0002006_tumorigenesis2.06731413
28MP0002098_abnormal_vibrissa_morphology2.04713795
29MP0010329_abnormal_lipoprotein_level2.01559031
30MP0010678_abnormal_skin_adnexa1.99144698
31MP0000579_abnormal_nail_morphology1.97408367
32MP0000647_abnormal_sebaceous_gland1.95179731
33MP0000377_abnormal_hair_follicle1.93428945
34MP0003705_abnormal_hypodermis_morpholog1.89503927
35MP0001835_abnormal_antigen_presentation1.85839424
36MP0005409_darkened_coat_color1.85234454
37MP0002060_abnormal_skin_morphology1.83133997
38MP0005167_abnormal_blood-brain_barrier1.81481908
39MP0003941_abnormal_skin_development1.79832644
40MP0001849_ear_inflammation1.77048463
41MP0000566_synostosis1.77043646
42MP0004947_skin_inflammation1.73263753
43MP0003191_abnormal_cellular_cholesterol1.69442790
44MP0005666_abnormal_adipose_tissue1.69024721
45MP0001216_abnormal_epidermal_layer1.61999856
46MP0010368_abnormal_lymphatic_system1.61472697
47MP0010771_integument_phenotype1.56741716
48MP0005387_immune_system_phenotype1.56080579
49MP0001790_abnormal_immune_system1.56080579
50MP0005275_abnormal_skin_tensile1.54385712
51MP0002249_abnormal_larynx_morphology1.54329004
52MP0004019_abnormal_vitamin_homeostasis1.53231178
53MP0003566_abnormal_cell_adhesion1.53202110
54MP0003453_abnormal_keratinocyte_physiol1.50529679
55MP0004381_abnormal_hair_follicle1.49952052
56MP0002089_abnormal_postnatal_growth/wei1.47177496
57MP0005083_abnormal_biliary_tract1.47085725
58MP0003303_peritoneal_inflammation1.45277029
59MP0009379_abnormal_foot_pigmentation1.43752114
60MP0001243_abnormal_dermal_layer1.43170645
61MP0001879_abnormal_lymphatic_vessel1.41879470
62MP0005367_renal/urinary_system_phenotyp1.35225777
63MP0000516_abnormal_urinary_system1.35225777
64MP0002234_abnormal_pharynx_morphology1.35167007
65MP0003123_paternal_imprinting1.32333862
66MP0003283_abnormal_digestive_organ1.30530994
67MP0000467_abnormal_esophagus_morphology1.28651380
68MP0003806_abnormal_nucleotide_metabolis1.28461562
69MP0005670_abnormal_white_adipose1.26131672
70MP0001958_emphysema1.26054307
71MP0004782_abnormal_surfactant_physiolog1.24998551
72MP0000367_abnormal_coat/_hair1.24814728
73MP0005397_hematopoietic_system_phenotyp1.24263750
74MP0001545_abnormal_hematopoietic_system1.24263750
75MP0001800_abnormal_humoral_immune1.24123695
76MP0004130_abnormal_muscle_cell1.24059420
77MP0003724_increased_susceptibility_to1.22253013
78MP0003638_abnormal_response/metabolism_1.20617636
79MP0002166_altered_tumor_susceptibility1.19487923
80MP0001666_abnormal_nutrient_absorption1.15756132
81MP0005671_abnormal_response_to1.15633438
82MP0000538_abnormal_urinary_bladder1.15571398
83MP0001765_abnormal_ion_homeostasis1.15415213
84MP0000767_abnormal_smooth_muscle1.15395435
85MP0004233_abnormal_muscle_weight1.14461232
86MP0000470_abnormal_stomach_morphology1.14180134
87MP0005375_adipose_tissue_phenotype1.13811192
88MP0002909_abnormal_adrenal_gland1.13519512
89MP0000609_abnormal_liver_physiology1.13192050
90MP0002396_abnormal_hematopoietic_system1.12627026
91MP0003183_abnormal_peptide_metabolism1.12346087
92MP0005332_abnormal_amino_acid1.12111701
93MP0002118_abnormal_lipid_homeostasis1.11876496
94MP0005075_abnormal_melanosome_morpholog1.11825243
95MP0009931_abnormal_skin_appearance1.10337233
96MP0000627_abnormal_mammary_gland1.09878942
97MP0000427_abnormal_hair_cycle1.09567120
98MP0009672_abnormal_birth_weight1.08844133
99MP0004145_abnormal_muscle_electrophysio1.08046558
100MP0001191_abnormal_skin_condition1.05551108
101MP0009643_abnormal_urine_homeostasis1.05298190
102MP0003693_abnormal_embryo_hatching1.03600512
103MP0000613_abnormal_salivary_gland1.02658245
104MP0002009_preneoplasia1.01336425
105MP0001881_abnormal_mammary_gland0.99147506
106MP0009697_abnormal_copulation0.99140315
107MP0003878_abnormal_ear_physiology0.98885789
108MP0005377_hearing/vestibular/ear_phenot0.98885789
109MP0005464_abnormal_platelet_physiology0.98681518
110MP0005025_abnormal_response_to0.95921419
111MP0004185_abnormal_adipocyte_glucose0.94640587
112MP0005257_abnormal_intraocular_pressure0.94350381
113MP0000477_abnormal_intestine_morphology0.93086241
114MP0001664_abnormal_digestion0.92400983
115MP0003075_altered_response_to0.92351478
116MP0002723_abnormal_immune_serum0.92340202
117MP0005023_abnormal_wound_healing0.92071871
118MP0002148_abnormal_hypersensitivity_rea0.91891419
119MP0003172_abnormal_lysosome_physiology0.90766811
120MP0005166_decreased_susceptibility_to0.89709782
121MP0000462_abnormal_digestive_system0.88252351
122MP0003300_gastrointestinal_ulcer0.87235918
123MP0008469_abnormal_protein_level0.87148549
124MP0002452_abnormal_antigen_presenting0.87119879
125MP0009384_cardiac_valve_regurgitation0.87061592
126MP0001730_embryonic_growth_arrest0.86582859
127MP0003045_fibrosis0.86432482
128MP0009764_decreased_sensitivity_to0.86196555
129MP0005000_abnormal_immune_tolerance0.85094283
130MP0005220_abnormal_exocrine_pancreas0.84686664
131MP0003656_abnormal_erythrocyte_physiolo0.83575070
132MP0000733_abnormal_muscle_development0.83004994
133MP0000534_abnormal_ureter_morphology0.82701903
134MP0003690_abnormal_glial_cell0.81009162
135MP0008260_abnormal_autophagy0.80802924
136MP0009785_altered_susceptibility_to0.80551898
137MP0002736_abnormal_nociception_after0.78733509
138MP0000490_abnormal_crypts_of0.77900031
139MP0002822_catalepsy0.77778488
140MP0002136_abnormal_kidney_physiology0.77761670
141MP0000762_abnormal_tongue_morphology0.77026729
142MP0001845_abnormal_inflammatory_respons0.75363608
143MP0000003_abnormal_adipose_tissue0.74874443
144MP0003879_abnormal_hair_cell0.74603244
145MP0000249_abnormal_blood_vessel0.72624680
146MP0005647_abnormal_sex_gland0.72610884
147MP0005319_abnormal_enzyme/_coenzyme0.71433160
148MP0005451_abnormal_body_composition0.70822395
149MP0005595_abnormal_vascular_smooth0.70513093
150MP0005584_abnormal_enzyme/coenzyme_acti0.70487324
151MP0002086_abnormal_extraembryonic_tissu0.68059697
152MP0004808_abnormal_hematopoietic_stem0.67162280
153MP0002420_abnormal_adaptive_immunity0.64780569
154MP0002970_abnormal_white_adipose0.64519352
155MP0000465_gastrointestinal_hemorrhage0.64150965
156MP0005058_abnormal_lysosome_morphology0.62096129
157MP0002080_prenatal_lethality0.61864150
158MP0010352_gastrointestinal_tract_polyps0.60565845
159MP0003984_embryonic_growth_retardation0.60236011
160MP0010630_abnormal_cardiac_muscle0.59387697
161MP0005448_abnormal_energy_balance0.59260761
162MP0003942_abnormal_urinary_system0.57279947
163MP0001944_abnormal_pancreas_morphology0.56356857
164MP0002088_abnormal_embryonic_growth/wei0.56055796
165MP0004510_myositis0.55712166
166MP0002111_abnormal_tail_morphology0.54834092
167MP0005380_embryogenesis_phenotype0.52154014
168MP0001672_abnormal_embryogenesis/_devel0.52154014
169MP0009053_abnormal_anal_canal0.51614192

Predicted human phenotypes

RankGene SetZ-score
1Spontaneous hematomas (HP:0007420)6.86305559
2Abnormality of the nasal mucosa (HP:0000433)6.72361702
3Hematochezia (HP:0002573)6.54071234
4Polycythemia (HP:0001901)5.36381312
5Systemic lupus erythematosus (HP:0002725)5.12576822
6Flat acetabular roof (HP:0003180)4.83745360
7Broad face (HP:0000283)4.38371316
8Conjunctival telangiectasia (HP:0000524)4.28583849
9Testicular atrophy (HP:0000029)4.16714531
10Abnormality of the 1st metacarpal (HP:0010009)4.09050748
11Intrahepatic cholestasis (HP:0001406)4.04434461
12Septate vagina (HP:0001153)3.91225916
13Hypotrichosis (HP:0001006)3.87041965
14Cerebral hemorrhage (HP:0001342)3.84725883
15Deep venous thrombosis (HP:0002625)3.84141560
16Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)3.83885585
17Short 1st metacarpal (HP:0010034)3.83885585
18Abnormality of aromatic amino acid family metabolism (HP:0004338)3.72329663
19Esophageal varix (HP:0002040)3.60651415
20Nasal polyposis (HP:0100582)3.58893476
21Microcytic anemia (HP:0001935)3.50562699
22Abnormal tarsal ossification (HP:0008369)3.48673515
23Abnormality of the vasculature of the conjunctiva (HP:0008054)3.46760005
24Lip pit (HP:0100267)3.44109723
25Abnormality of the distal phalanx of the thumb (HP:0009617)3.43236543
26Abnormality of the distal phalanges of the toes (HP:0010182)3.39159791
27Flattened epiphyses (HP:0003071)3.26882701
28Increased IgE level (HP:0003212)3.22487859
29Xanthomatosis (HP:0000991)3.22140631
30Abnormality of the common coagulation pathway (HP:0010990)3.16773457
31Abnormality of carpal bone ossification (HP:0006257)3.10288189
32Petechiae (HP:0000967)3.07241727
33White forelock (HP:0002211)3.06350843
34Abnormality of monocarboxylic acid metabolism (HP:0010996)3.01899484
35Short phalanx of the thumb (HP:0009660)3.01821554
36Pulmonary embolism (HP:0002204)3.00897694
37Amelogenesis imperfecta (HP:0000705)2.96841783
38Thin bony cortex (HP:0002753)2.95529656
39Cervical subluxation (HP:0003308)2.91315491
40Complement deficiency (HP:0004431)2.90010602
41Hyperacusis (HP:0010780)2.88971409
42Abnormality of the phalanges of the hallux (HP:0010057)2.86584042
43Vascular calcification (HP:0004934)2.85265513
44J-shaped sella turcica (HP:0002680)2.82538809
45Joint hemorrhage (HP:0005261)2.81124459
46Abnormal delayed hypersensitivity skin test (HP:0002963)2.79988918
47Growth hormone excess (HP:0000845)2.79927533
48Prolonged partial thromboplastin time (HP:0003645)2.79460684
49Patchy hypopigmentation of hair (HP:0011365)2.79200415
50Parakeratosis (HP:0001036)2.78451658
51Visceral angiomatosis (HP:0100761)2.76810402
52Abnormality of the fingertips (HP:0001211)2.75653341
53Germ cell neoplasia (HP:0100728)2.70928601
54Bronchomalacia (HP:0002780)2.67920780
55Hemangiomatosis (HP:0007461)2.66163091
56Microretrognathia (HP:0000308)2.59294218
57Sparse lateral eyebrow (HP:0005338)2.57037938
58Epistaxis (HP:0000421)2.56199477
59Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.55343685
60Pili torti (HP:0003777)2.55064681
61Cardiovascular calcification (HP:0011915)2.54482017
62Abnormality of complement system (HP:0005339)2.54080257
63Thrombophlebitis (HP:0004418)2.51904868
64Abnormal ossification of hand bones (HP:0005921)2.49839647
65Obstructive sleep apnea (HP:0002870)2.49128682
66Hyperlipoproteinemia (HP:0010980)2.46931965
67Woolly hair (HP:0002224)2.44727786
68Ankle clonus (HP:0011448)2.44426777
69Curly hair (HP:0002212)2.42630270
70Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.40152121
71Spontaneous abortion (HP:0005268)2.38993213
72Abnormal hand bone ossification (HP:0010660)2.38746145
73Ureteral stenosis (HP:0000071)2.38484916
74Stridor (HP:0010307)2.37650041
75Abnormality of the proximal phalanges of the hand (HP:0009834)2.36869516
76Congenital glaucoma (HP:0001087)2.36706086
77Interstitial pulmonary disease (HP:0006530)2.35858234
78Spinal cord compression (HP:0002176)2.35835213
79Abnormal foot bone ossification (HP:0010675)2.33266368
80Milia (HP:0001056)2.32384413
81Axonal loss (HP:0003447)2.31304315
82Achilles tendon contracture (HP:0001771)2.31240899
83Epidermoid cyst (HP:0200040)2.30261768
84Bulbar palsy (HP:0001283)2.30040100
85Stroke (HP:0001297)2.29392579
86Hypobetalipoproteinemia (HP:0003563)2.29062223
87Broad metatarsal (HP:0001783)2.28895066
88Portal hypertension (HP:0001409)2.28718202
89Recurrent bronchitis (HP:0002837)2.25872159
90Poor suck (HP:0002033)2.24097174
91Pendular nystagmus (HP:0012043)2.23733259
92Abnormality of the Achilles tendon (HP:0005109)2.22519096
93Prolonged neonatal jaundice (HP:0006579)2.21295589
94Onycholysis (HP:0001806)2.20565765
95Mucosal telangiectasiae (HP:0100579)2.17905070
96Abnormality of the hepatic vasculature (HP:0006707)2.15627590
97Intestinal polyposis (HP:0200008)2.15193296
98Short nail (HP:0001799)2.14063571
99Lymphangioma (HP:0100764)2.13928388
100Aplasia/hypoplasia of the femur (HP:0005613)2.13201336
101Advanced eruption of teeth (HP:0006288)2.13029807
102Urethral obstruction (HP:0000796)2.12503023
103Abnormality of glutamine family amino acid metabolism (HP:0010902)2.11828539
104Pruritus (HP:0000989)2.10780417
105Hypoalphalipoproteinemia (HP:0003233)2.10661573
106Ureteral obstruction (HP:0006000)2.10193808
107Pterygium (HP:0001059)2.10019703
108Testicular neoplasm (HP:0010788)2.09367440
109Abnormality of nail color (HP:0100643)2.09176143
110Abnormality of fatty-acid metabolism (HP:0004359)2.08613266
111Myopathic facies (HP:0002058)2.08336096
112Hyperkalemia (HP:0002153)2.07543872
113Myokymia (HP:0002411)2.06802408
114Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.05745625
115Hyperthyroidism (HP:0000836)2.05559636
116Hypoglycemic coma (HP:0001325)2.03832229
117Abnormal vertebral ossification (HP:0100569)2.03478204
118Abnormality of the intrinsic pathway (HP:0010989)2.02997268
119Ketosis (HP:0001946)2.02889882
120Hypochromic anemia (HP:0001931)2.02394818
12111 pairs of ribs (HP:0000878)2.01061079
122Intestinal polyp (HP:0005266)2.01029551
123Seborrheic dermatitis (HP:0001051)2.00496518
124Hypolipoproteinemia (HP:0010981)2.00337397
125Easy fatigability (HP:0003388)1.99756173
126Myocardial infarction (HP:0001658)1.98395173
127Abnormal hair laboratory examination (HP:0003328)1.98043211
128Severe visual impairment (HP:0001141)1.96434988
129Dicarboxylic aciduria (HP:0003215)1.95794656
130Abnormality of dicarboxylic acid metabolism (HP:0010995)1.95794656
131Gingival bleeding (HP:0000225)1.93744566
132Plantar hyperkeratosis (HP:0007556)1.92724284
133Abnormality of aspartate family amino acid metabolism (HP:0010899)1.92588734
134Fat malabsorption (HP:0002630)1.92513293
135Popliteal pterygium (HP:0009756)1.92049814
136Abnormality of methionine metabolism (HP:0010901)1.90937872
137Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.90776575
138Deviation of the thumb (HP:0009603)1.90105976
139Dysmetric saccades (HP:0000641)1.88825418
140Hemorrhage of the eye (HP:0011885)1.88016353
141Severe short stature (HP:0003510)1.86905768
142Distal upper limb amyotrophy (HP:0007149)1.86670926
143Upper limb amyotrophy (HP:0009129)1.86670926
144Palmoplantar hyperkeratosis (HP:0000972)1.86193479
145Hyperactive renin-angiotensin system (HP:0000841)1.86153834
146Fragile nails (HP:0001808)1.85735697
147Anal stenosis (HP:0002025)1.85675442
148Gastrointestinal infarctions (HP:0005244)1.85472911
149Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.85398092
150Partial duplication of the phalanx of hand (HP:0009999)1.85001577
151Long palpebral fissure (HP:0000637)1.84693565
152Abnormality of sulfur amino acid metabolism (HP:0004339)1.84090136
153Partial duplication of thumb phalanx (HP:0009944)1.83965004
154Hypoparathyroidism (HP:0000829)1.83945883
155Diaphragmatic weakness (HP:0009113)1.82792249
156Micronodular cirrhosis (HP:0001413)1.82220752
157Macroorchidism (HP:0000053)1.81879483
158Alopecia of scalp (HP:0002293)1.81429460
159Hypercholesterolemia (HP:0003124)1.81298050
160Cavernous hemangioma (HP:0001048)1.80462230
161Distal lower limb amyotrophy (HP:0008944)1.79762184
162Prostate neoplasm (HP:0100787)1.79685151
163Ridged nail (HP:0001807)1.79394476
164Hypoplasia of dental enamel (HP:0006297)1.79218566
165Colon cancer (HP:0003003)1.79051464
166Patellar dislocation (HP:0002999)1.78801684
167Neonatal death (HP:0003811)1.78216190
168Elevated alkaline phosphatase (HP:0003155)1.77833735
169Conjugated hyperbilirubinemia (HP:0002908)1.77795132
170Mesangial abnormality (HP:0001966)1.76235440
171Shallow orbits (HP:0000586)1.75668550
172Hyperparathyroidism (HP:0000843)1.75368703
173Hemoptysis (HP:0002105)1.75294372
174Bronchitis (HP:0012387)1.75239903
175Chondrocalcinosis (HP:0000934)1.75151036
176Recurrent sinusitis (HP:0011108)1.74152911
177Hyperammonemia (HP:0001987)1.74104681
178Abnormality of the gastric mucosa (HP:0004295)1.73425264
179Erythema (HP:0010783)1.72865020
180Short femoral neck (HP:0100864)1.72484266
181Aneurysm (HP:0002617)1.71170016
182Mildly elevated creatine phosphokinase (HP:0008180)1.71043584
183Hyperglycinemia (HP:0002154)1.70139753
184Stomach cancer (HP:0012126)1.69695922
185Right ventricular cardiomyopathy (HP:0011663)1.69455121
186Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.69322652
187Back pain (HP:0003418)1.69244770
188Malnutrition (HP:0004395)1.68470141
189Prolonged bleeding time (HP:0003010)1.66710049
190Hypertriglyceridemia (HP:0002155)1.65798294

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR27.60400130
2TGFBR16.66954205
3TIE14.76586706
4CAMK1D4.43741605
5EPHA24.43382138
6TAOK14.24597107
7SMG13.64339588
8STK163.60019643
9CAMK1G3.19613896
10NME22.69622093
11CDK122.59037914
12IRAK32.57674647
13TNK22.50244706
14BUB12.43429404
15BLK2.39488843
16MAP4K12.26800948
17PRKD22.25308596
18ARAF2.10936848
19MARK22.06631809
20LRRK22.04925586
21PKN22.02238229
22FGFR41.94949527
23CSF1R1.93782094
24PRKD31.91665426
25PIM21.88257897
26PRKCI1.88170102
27LMTK21.76197808
28RIPK41.42848644
29TESK11.41825021
30EPHB11.36481580
31IRAK21.34510862
32MAP3K101.25756446
33MAP3K31.24925703
34MAP2K61.23659298
35ERN11.21126126
36KDR1.18201377
37MTOR1.16205057
38RIPK11.13122871
39RPS6KA41.10701617
40EEF2K1.05120026
41SCYL21.04969817
42EPHA31.04685558
43MAPKAPK51.03172389
44SYK0.96550868
45GRK60.96126534
46MUSK0.91295171
47MAPKAPK30.90648898
48SIK10.89150385
49MAP2K20.88002966
50MET0.87969053
51TBK10.87741148
52HIPK20.86030242
53IRAK10.85838166
54BRD40.84452381
55FGR0.82868475
56MAP2K30.80481460
57MAPK120.80020402
58PRKCQ0.79507976
59PTK2B0.78520976
60PRPF4B0.78497576
61MAP2K10.78152225
62ICK0.76753582
63JAK10.76256466
64MAP3K110.76062695
65FES0.75554393
66STK390.75308147
67RPS6KB20.74247343
68CHUK0.74033988
69FER0.73778457
70PAK40.73770442
71CDK70.73129164
72CDK90.72511405
73SIK30.70143717
74KIT0.69113073
75BTK0.66826221
76PTK60.64517874
77PDK30.63249485
78PDK40.63249485
79PRKD10.63074243
80TYK20.63030591
81BCKDK0.61980074
82ALK0.61021916
83TAOK30.58979768
84TRIB30.57507765
85IKBKE0.56741330
86RPS6KA20.56574683
87MAP3K140.56121483
88RPS6KA50.56088908
89PRKAA10.54828507
90MAP3K130.54397507
91MAP3K20.53718986
92MAPK150.53717624
93CDK190.52808807
94GRK10.51860597
95IRAK40.50151545
96STK100.49744176
97MAP3K90.48809855
98BMX0.48466622
99DDR20.46068397
100MAPK70.45235513
101NLK0.44626857
102FGFR30.44040153
103ZAP700.43975578
104OXSR10.43954778
105MAPK80.41716166
106CDC42BPA0.41457992
107BRAF0.39727291
108PDK20.39261339
109RAF10.38466051
110NTRK20.38210701
111MAPK40.37425728
112ILK0.37344096
113JAK20.37214764
114CDK30.36662862
115AKT30.35416410
116DYRK1B0.35340864
117CSK0.35261473
118LYN0.34883937
119MAP3K10.33837590
120NME10.33651833
121AURKA0.33483662
122CAMKK10.33465057
123IKBKB0.33384933
124WNK40.32985347
125MAPK110.32906675
126JAK30.32885464
127RPS6KL10.32674743
128RPS6KC10.32674743
129LCK0.32145002
130DAPK20.31469561
131MAPK100.29851528
132TEC0.29397095
133PDK10.29279969
134RPS6KA60.29059049
135EPHB20.28836610
136FGFR20.28678891
137RET0.28124181
138CAMK10.27408323
139PRKG20.27332785
140TESK20.27322078
141PTK20.27287617
142PDGFRA0.26545217
143MST1R0.26283310
144TAOK20.26141889
145CSNK1G30.25803561
146MAP3K70.24510987
147LATS20.24303472
148ERBB40.23910505
149AKT20.23800764
150GSK3B0.23384664
151PRKCZ0.23148086
152SIK20.23042519
153MAP3K80.23006717
154PRKAA20.22803096
155STK110.22402741
156PDPK10.22068755
157PHKG20.21436909
158PHKG10.21436909
159RPS6KA10.20623571

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.17977930
2Cyanoamino acid metabolism_Homo sapiens_hsa004603.61671984
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.20915470
4Nitrogen metabolism_Homo sapiens_hsa009102.84328348
5Notch signaling pathway_Homo sapiens_hsa043302.76654508
6Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.74995977
7Renin-angiotensin system_Homo sapiens_hsa046142.66367372
8Complement and coagulation cascades_Homo sapiens_hsa046102.62859641
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.51961884
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.47490102
11Arginine biosynthesis_Homo sapiens_hsa002202.37762964
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.36856077
13Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.27391894
14Butanoate metabolism_Homo sapiens_hsa006502.24104927
15Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.20710269
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.17481483
17Fatty acid degradation_Homo sapiens_hsa000712.06661592
18Staphylococcus aureus infection_Homo sapiens_hsa051502.04392108
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.99682428
20PPAR signaling pathway_Homo sapiens_hsa033201.94928553
21Tryptophan metabolism_Homo sapiens_hsa003801.94678676
22AMPK signaling pathway_Homo sapiens_hsa041521.89606054
23ABC transporters_Homo sapiens_hsa020101.87966244
24Bile secretion_Homo sapiens_hsa049761.87193924
25Chemical carcinogenesis_Homo sapiens_hsa052041.83973278
26Insulin signaling pathway_Homo sapiens_hsa049101.80975900
27Folate biosynthesis_Homo sapiens_hsa007901.79273436
28Other glycan degradation_Homo sapiens_hsa005111.77858612
29Phenylalanine metabolism_Homo sapiens_hsa003601.72247814
30Peroxisome_Homo sapiens_hsa041461.65366871
31Propanoate metabolism_Homo sapiens_hsa006401.58494670
32Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.57579811
33Prostate cancer_Homo sapiens_hsa052151.52714206
34Histidine metabolism_Homo sapiens_hsa003401.49951121
35Endometrial cancer_Homo sapiens_hsa052131.48260001
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.47108925
37Retinol metabolism_Homo sapiens_hsa008301.46828239
38Thyroid cancer_Homo sapiens_hsa052161.44991827
39Fatty acid metabolism_Homo sapiens_hsa012121.44028278
40Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.43466808
41Lysine degradation_Homo sapiens_hsa003101.42563546
42Longevity regulating pathway - mammal_Homo sapiens_hsa042111.39487431
43Chronic myeloid leukemia_Homo sapiens_hsa052201.39142638
44alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.35934076
45Thyroid hormone signaling pathway_Homo sapiens_hsa049191.31016604
46Estrogen signaling pathway_Homo sapiens_hsa049151.28567372
47ErbB signaling pathway_Homo sapiens_hsa040121.23805380
48Fructose and mannose metabolism_Homo sapiens_hsa000511.22454418
49Fatty acid elongation_Homo sapiens_hsa000621.22342280
50Sulfur relay system_Homo sapiens_hsa041221.19937609
51Linoleic acid metabolism_Homo sapiens_hsa005911.19167418
52Tight junction_Homo sapiens_hsa045301.14592122
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.11655076
54Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09794483
55Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.07318501
56Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.06632116
57Tyrosine metabolism_Homo sapiens_hsa003501.06182104
58GnRH signaling pathway_Homo sapiens_hsa049121.06115828
59N-Glycan biosynthesis_Homo sapiens_hsa005101.05793524
60mTOR signaling pathway_Homo sapiens_hsa041501.05558544
61Thyroid hormone synthesis_Homo sapiens_hsa049181.03939520
62Choline metabolism in cancer_Homo sapiens_hsa052311.03836463
63Vitamin digestion and absorption_Homo sapiens_hsa049771.02696984
64Bladder cancer_Homo sapiens_hsa052191.02547575
65Fat digestion and absorption_Homo sapiens_hsa049751.01069070
66Central carbon metabolism in cancer_Homo sapiens_hsa052301.00196526
67Pentose and glucuronate interconversions_Homo sapiens_hsa000401.00033026
68Hepatitis C_Homo sapiens_hsa051600.99628056
69Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.98587490
70Caffeine metabolism_Homo sapiens_hsa002320.98164219
71Steroid hormone biosynthesis_Homo sapiens_hsa001400.93240734
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.92037599
73Neurotrophin signaling pathway_Homo sapiens_hsa047220.91956688
74Non-small cell lung cancer_Homo sapiens_hsa052230.91351488
75Primary immunodeficiency_Homo sapiens_hsa053400.90442499
76Pyruvate metabolism_Homo sapiens_hsa006200.88695894
77Base excision repair_Homo sapiens_hsa034100.87814083
78Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.86952296
79B cell receptor signaling pathway_Homo sapiens_hsa046620.86201507
80Biosynthesis of amino acids_Homo sapiens_hsa012300.84693328
81Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.84311312
82Aldosterone synthesis and secretion_Homo sapiens_hsa049250.82493837
83VEGF signaling pathway_Homo sapiens_hsa043700.81147162
84Glycosaminoglycan degradation_Homo sapiens_hsa005310.81137437
85Fatty acid biosynthesis_Homo sapiens_hsa000610.78966698
86Inositol phosphate metabolism_Homo sapiens_hsa005620.78532642
87Pentose phosphate pathway_Homo sapiens_hsa000300.78202940
88beta-Alanine metabolism_Homo sapiens_hsa004100.76992152
89Vibrio cholerae infection_Homo sapiens_hsa051100.74595796
90Carbon metabolism_Homo sapiens_hsa012000.73977619
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.70487769
92Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.69614082
93Type II diabetes mellitus_Homo sapiens_hsa049300.67275830
94Melanogenesis_Homo sapiens_hsa049160.67262917
95Long-term potentiation_Homo sapiens_hsa047200.67055562
96mRNA surveillance pathway_Homo sapiens_hsa030150.65599317
97Axon guidance_Homo sapiens_hsa043600.65512444
98Glutathione metabolism_Homo sapiens_hsa004800.65373274
99Steroid biosynthesis_Homo sapiens_hsa001000.64731552
100Adipocytokine signaling pathway_Homo sapiens_hsa049200.62963225
101Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62118282
102Taste transduction_Homo sapiens_hsa047420.62020230
103Phospholipase D signaling pathway_Homo sapiens_hsa040720.60662519
104African trypanosomiasis_Homo sapiens_hsa051430.59947154
105Endocytosis_Homo sapiens_hsa041440.59687618
106Drug metabolism - other enzymes_Homo sapiens_hsa009830.58980069
107Galactose metabolism_Homo sapiens_hsa000520.58882874
108Small cell lung cancer_Homo sapiens_hsa052220.57362418
109Arginine and proline metabolism_Homo sapiens_hsa003300.56486557
110Basal cell carcinoma_Homo sapiens_hsa052170.55667885
111Ether lipid metabolism_Homo sapiens_hsa005650.55551344
112Cholinergic synapse_Homo sapiens_hsa047250.55012048
113MicroRNAs in cancer_Homo sapiens_hsa052060.54881629
114Adherens junction_Homo sapiens_hsa045200.54062222
115Platelet activation_Homo sapiens_hsa046110.53776162
116Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.53056330
117Renal cell carcinoma_Homo sapiens_hsa052110.52913685
118Arachidonic acid metabolism_Homo sapiens_hsa005900.52556710
119Prolactin signaling pathway_Homo sapiens_hsa049170.52459479
120Proteoglycans in cancer_Homo sapiens_hsa052050.50063009
121Hippo signaling pathway_Homo sapiens_hsa043900.48080903
122Glioma_Homo sapiens_hsa052140.48066047
123Transcriptional misregulation in cancer_Homo sapiens_hsa052020.47409225
124Ribosome_Homo sapiens_hsa030100.46411848
125Insulin resistance_Homo sapiens_hsa049310.46127393
126Vitamin B6 metabolism_Homo sapiens_hsa007500.45740743
127Leukocyte transendothelial migration_Homo sapiens_hsa046700.44844618
128Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.42869421
129Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.41666849
130Rap1 signaling pathway_Homo sapiens_hsa040150.41432664
131Gap junction_Homo sapiens_hsa045400.41155172
132Acute myeloid leukemia_Homo sapiens_hsa052210.40649122
133Long-term depression_Homo sapiens_hsa047300.40450966
134Prion diseases_Homo sapiens_hsa050200.39740009
135Sphingolipid metabolism_Homo sapiens_hsa006000.39206414
136MAPK signaling pathway_Homo sapiens_hsa040100.38994339
137Ovarian steroidogenesis_Homo sapiens_hsa049130.38783810
138Sphingolipid signaling pathway_Homo sapiens_hsa040710.37786485
139Glycerolipid metabolism_Homo sapiens_hsa005610.37622195
140Renin secretion_Homo sapiens_hsa049240.36483306
141Synaptic vesicle cycle_Homo sapiens_hsa047210.36249979
142Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36238189
143Insulin secretion_Homo sapiens_hsa049110.35148546
144Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.35085012
145Antigen processing and presentation_Homo sapiens_hsa046120.34951170
146Pancreatic cancer_Homo sapiens_hsa052120.34815355
147Cocaine addiction_Homo sapiens_hsa050300.34489099
1482-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.33884740
149Vascular smooth muscle contraction_Homo sapiens_hsa042700.30848980
150Amoebiasis_Homo sapiens_hsa051460.30612167
151Maturity onset diabetes of the young_Homo sapiens_hsa049500.28302399
152Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.27978660
153Pancreatic secretion_Homo sapiens_hsa049720.27687461
154Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.27622144
155Dorso-ventral axis formation_Homo sapiens_hsa043200.27074270
156Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.23698611
157Gastric acid secretion_Homo sapiens_hsa049710.20888970
158Shigellosis_Homo sapiens_hsa051310.20128103
159Selenocompound metabolism_Homo sapiens_hsa004500.19462211
160Starch and sucrose metabolism_Homo sapiens_hsa005000.18498899
161Glucagon signaling pathway_Homo sapiens_hsa049220.17959638
162Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.17268774
163Intestinal immune network for IgA production_Homo sapiens_hsa046720.17056789
164Osteoclast differentiation_Homo sapiens_hsa043800.16402760
165Metabolic pathways_Homo sapiens_hsa011000.15209272
166Sulfur metabolism_Homo sapiens_hsa009200.15049827
167Glycerophospholipid metabolism_Homo sapiens_hsa005640.14732754
168Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.13052770
169Influenza A_Homo sapiens_hsa051640.12699031

Most similar genes based on co-expression Upload to Enrichr

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