

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neuronal action potential propagation (GO:0019227) | 8.86581617 |
| 2 | histone H3-K9 demethylation (GO:0033169) | 6.87069334 |
| 3 | positive regulation of protein homooligomerization (GO:0032464) | 6.11454115 |
| 4 | gamma-aminobutyric acid transport (GO:0015812) | 5.73788792 |
| 5 | Peyers patch development (GO:0048541) | 5.06844173 |
| 6 | mucosal-associated lymphoid tissue development (GO:0048537) | 5.06844173 |
| 7 | cytoplasmic mRNA processing body assembly (GO:0033962) | 4.80642965 |
| 8 | detection of light stimulus involved in visual perception (GO:0050908) | 4.18233618 |
| 9 | detection of light stimulus involved in sensory perception (GO:0050962) | 4.18233618 |
| 10 | striated muscle atrophy (GO:0014891) | 4.12787725 |
| 11 | interkinetic nuclear migration (GO:0022027) | 4.05540968 |
| 12 | regulation of RNA export from nucleus (GO:0046831) | 3.98672086 |
| 13 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.98503876 |
| 14 | muscle atrophy (GO:0014889) | 3.96735346 |
| 15 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 3.91525124 |
| 16 | protein dealkylation (GO:0008214) | 3.90911021 |
| 17 | protein demethylation (GO:0006482) | 3.90911021 |
| 18 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 3.88083917 |
| 19 | skeletal muscle adaptation (GO:0043501) | 3.83655975 |
| 20 | alternative mRNA splicing, via spliceosome (GO:0000380) | 3.80637335 |
| 21 | positive regulation of mitochondrial fission (GO:0090141) | 3.75796311 |
| 22 | pyrimidine dimer repair (GO:0006290) | 3.67085686 |
| 23 | regulation of mRNA catabolic process (GO:0061013) | 3.67011068 |
| 24 | acrosome reaction (GO:0007340) | 3.65968073 |
| 25 | mitochondrion morphogenesis (GO:0070584) | 3.64494782 |
| 26 | regulation of exit from mitosis (GO:0007096) | 3.63589705 |
| 27 | histone H2A acetylation (GO:0043968) | 3.61970240 |
| 28 | regulation of chromatin binding (GO:0035561) | 3.61705057 |
| 29 | generation of neurons (GO:0048699) | 3.53472806 |
| 30 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.53177792 |
| 31 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.53177792 |
| 32 | histone demethylation (GO:0016577) | 3.51773369 |
| 33 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.49122846 |
| 34 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 3.48663067 |
| 35 | mitotic G2 DNA damage checkpoint (GO:0007095) | 3.44471759 |
| 36 | protein-chromophore linkage (GO:0018298) | 3.43599897 |
| 37 | hepatocyte apoptotic process (GO:0097284) | 3.43164520 |
| 38 | cell wall macromolecule catabolic process (GO:0016998) | 3.39930159 |
| 39 | histone lysine demethylation (GO:0070076) | 3.39816700 |
| 40 | positive regulation of mRNA catabolic process (GO:0061014) | 3.38233933 |
| 41 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.35608915 |
| 42 | mitochondrial fission (GO:0000266) | 3.35044277 |
| 43 | serotonin metabolic process (GO:0042428) | 3.34098433 |
| 44 | male meiosis (GO:0007140) | 3.31940573 |
| 45 | negative regulation of phosphoprotein phosphatase activity (GO:0032515) | 3.29042671 |
| 46 | regulation of mRNA splicing, via spliceosome (GO:0048024) | 3.27228436 |
| 47 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.26590195 |
| 48 | adaptation of signaling pathway (GO:0023058) | 3.19110631 |
| 49 | primary amino compound metabolic process (GO:1901160) | 3.18101869 |
| 50 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.17221656 |
| 51 | ventricular septum development (GO:0003281) | 3.16843075 |
| 52 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.15608232 |
| 53 | protein K48-linked deubiquitination (GO:0071108) | 3.12646797 |
| 54 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 3.11493087 |
| 55 | endothelial tube morphogenesis (GO:0061154) | 3.11407880 |
| 56 | morphogenesis of an endothelium (GO:0003159) | 3.11407880 |
| 57 | N-terminal protein amino acid acetylation (GO:0006474) | 3.08292156 |
| 58 | seminiferous tubule development (GO:0072520) | 3.07417777 |
| 59 | regulation of mRNA metabolic process (GO:1903311) | 3.05493916 |
| 60 | thymus development (GO:0048538) | 3.03606749 |
| 61 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.02022658 |
| 62 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.02022658 |
| 63 | negative regulation of TOR signaling (GO:0032007) | 3.01718811 |
| 64 | replication fork processing (GO:0031297) | 3.01608358 |
| 65 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.99164670 |
| 66 | positive regulation of dendrite morphogenesis (GO:0050775) | 2.98864912 |
| 67 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.96956963 |
| 68 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.96956963 |
| 69 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.96956963 |
| 70 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.94517468 |
| 71 | meiotic cell cycle (GO:0051321) | 2.94460232 |
| 72 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 2.93831362 |
| 73 | Notch signaling involved in heart development (GO:0061314) | 2.93169125 |
| 74 | regulation of mRNA processing (GO:0050684) | 2.91013633 |
| 75 | regulation of protein oligomerization (GO:0032459) | 2.87963959 |
| 76 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 2.86504296 |
| 77 | positive regulation of protein oligomerization (GO:0032461) | 2.86426200 |
| 78 | retinal rod cell development (GO:0046548) | 2.85745627 |
| 79 | response to methylmercury (GO:0051597) | 2.85649796 |
| 80 | adult walking behavior (GO:0007628) | 2.85281844 |
| 81 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.84364663 |
| 82 | positive regulation of mRNA metabolic process (GO:1903313) | 2.83956535 |
| 83 | mitotic G2/M transition checkpoint (GO:0044818) | 2.83019689 |
| 84 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.82443075 |
| 85 | regulation of mRNA 3-end processing (GO:0031440) | 2.82322642 |
| 86 | regulation of protein homooligomerization (GO:0032462) | 2.82320446 |
| 87 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.80839225 |
| 88 | peroxisome fission (GO:0016559) | 2.79983858 |
| 89 | negative thymic T cell selection (GO:0045060) | 2.79735624 |
| 90 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.77237847 |
| 91 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.77237847 |
| 92 | cardiac septum development (GO:0003279) | 2.74679124 |
| 93 | negative regulation of mast cell activation (GO:0033004) | 2.74174152 |
| 94 | positive regulation of mRNA 3-end processing (GO:0031442) | 2.74159106 |
| 95 | potassium ion export (GO:0071435) | 2.73428820 |
| 96 | startle response (GO:0001964) | 2.72129780 |
| 97 | regulation of timing of cell differentiation (GO:0048505) | 2.71366755 |
| 98 | tyrosine phosphorylation of STAT protein (GO:0007260) | 2.71236222 |
| 99 | regulation of mitochondrial fission (GO:0090140) | 2.70195341 |
| 100 | mitochondrial RNA metabolic process (GO:0000959) | 2.66917248 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.47604132 |
| 2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 5.09655326 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.66139837 |
| 4 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 4.52558849 |
| 5 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 4.03980130 |
| 6 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.74198155 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.68516656 |
| 8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.39814336 |
| 9 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.87027589 |
| 10 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.76847119 |
| 11 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.48859915 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.44197815 |
| 13 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.26008250 |
| 14 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.18118490 |
| 15 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.06791477 |
| 16 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.98470707 |
| 17 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.94297105 |
| 18 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.92072168 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.91217480 |
| 20 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.91178219 |
| 21 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.90048449 |
| 22 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.88084414 |
| 23 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.87598587 |
| 24 | GATA1_22025678_ChIP-Seq_K562_Human | 1.86493318 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.84421998 |
| 26 | STAT3_23295773_ChIP-Seq_U87_Human | 1.71363014 |
| 27 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.61669509 |
| 28 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.58794461 |
| 29 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.58432656 |
| 30 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.52729710 |
| 31 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.52073737 |
| 32 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.51215648 |
| 33 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.45335254 |
| 34 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.44037649 |
| 35 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.43029044 |
| 36 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.42935711 |
| 37 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.42715579 |
| 38 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.40722718 |
| 39 | P300_19829295_ChIP-Seq_ESCs_Human | 1.39559620 |
| 40 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.38711199 |
| 41 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.36905633 |
| 42 | EWS_26573619_Chip-Seq_HEK293_Human | 1.34915424 |
| 43 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.33195058 |
| 44 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.31921497 |
| 45 | TP53_16413492_ChIP-PET_HCT116_Human | 1.30133505 |
| 46 | TCF4_23295773_ChIP-Seq_U87_Human | 1.27786347 |
| 47 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.24430578 |
| 48 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.23339485 |
| 49 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.22994061 |
| 50 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.22925199 |
| 51 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.21133643 |
| 52 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.21099084 |
| 53 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.20231560 |
| 54 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.19085283 |
| 55 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.19021247 |
| 56 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.16277648 |
| 57 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.09771323 |
| 58 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08707404 |
| 59 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.08645009 |
| 60 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.07473308 |
| 61 | GATA3_26560356_Chip-Seq_TH2_Human | 1.07134312 |
| 62 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.04984283 |
| 63 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04660108 |
| 64 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.04560847 |
| 65 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.03797215 |
| 66 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.03075513 |
| 67 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.02971377 |
| 68 | AR_25329375_ChIP-Seq_VCAP_Human | 1.02850051 |
| 69 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.00768391 |
| 70 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.00017227 |
| 71 | FUS_26573619_Chip-Seq_HEK293_Human | 0.99566414 |
| 72 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.99523887 |
| 73 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.99516413 |
| 74 | JUN_21703547_ChIP-Seq_K562_Human | 0.98476116 |
| 75 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.96490494 |
| 76 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.95910383 |
| 77 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.95199237 |
| 78 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.93621039 |
| 79 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.93433087 |
| 80 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.92607748 |
| 81 | GATA3_26560356_Chip-Seq_TH1_Human | 0.89721882 |
| 82 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.89151509 |
| 83 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.89107818 |
| 84 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.89107818 |
| 85 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.88812832 |
| 86 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.87751737 |
| 87 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86545151 |
| 88 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.85433265 |
| 89 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.85187125 |
| 90 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.84775690 |
| 91 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.83904326 |
| 92 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.83778814 |
| 93 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.83462751 |
| 94 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.82732433 |
| 95 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.82447750 |
| 96 | RXR_22108803_ChIP-Seq_LS180_Human | 0.82375708 |
| 97 | MYB_26560356_Chip-Seq_TH2_Human | 0.82351250 |
| 98 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.80931760 |
| 99 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.80845328 |
| 100 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.80633660 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 5.43903670 |
| 2 | MP0002837_dystrophic_cardiac_calcinosis | 3.88603142 |
| 3 | MP0001346_abnormal_lacrimal_gland | 3.57350727 |
| 4 | MP0005645_abnormal_hypothalamus_physiol | 3.51595341 |
| 5 | MP0003646_muscle_fatigue | 3.44722515 |
| 6 | MP0010094_abnormal_chromosome_stability | 2.83944670 |
| 7 | MP0009046_muscle_twitch | 2.76378262 |
| 8 | MP0005623_abnormal_meninges_morphology | 2.72469583 |
| 9 | MP0003656_abnormal_erythrocyte_physiolo | 2.63874337 |
| 10 | MP0004084_abnormal_cardiac_muscle | 2.63838394 |
| 11 | MP0002163_abnormal_gland_morphology | 2.53252652 |
| 12 | MP0001348_abnormal_lacrimal_gland | 2.35846682 |
| 13 | MP0002396_abnormal_hematopoietic_system | 2.28417055 |
| 14 | MP0002102_abnormal_ear_morphology | 2.27984041 |
| 15 | MP0004885_abnormal_endolymph | 1.86185009 |
| 16 | MP0005379_endocrine/exocrine_gland_phen | 1.73774298 |
| 17 | MP0003763_abnormal_thymus_physiology | 1.71808581 |
| 18 | MP0008789_abnormal_olfactory_epithelium | 1.65127619 |
| 19 | MP0005171_absent_coat_pigmentation | 1.64970326 |
| 20 | MP0005671_abnormal_response_to | 1.59294519 |
| 21 | MP0004742_abnormal_vestibular_system | 1.59246584 |
| 22 | MP0005174_abnormal_tail_pigmentation | 1.52812741 |
| 23 | MP0001502_abnormal_circadian_rhythm | 1.52008584 |
| 24 | MP0003950_abnormal_plasma_membrane | 1.51986617 |
| 25 | MP0000371_diluted_coat_color | 1.48922368 |
| 26 | MP0003943_abnormal_hepatobiliary_system | 1.42069489 |
| 27 | MP0005248_abnormal_Harderian_gland | 1.34686820 |
| 28 | MP0005310_abnormal_salivary_gland | 1.33805146 |
| 29 | MP0004147_increased_porphyrin_level | 1.32354405 |
| 30 | MP0008057_abnormal_DNA_replication | 1.31689005 |
| 31 | MP0004859_abnormal_synaptic_plasticity | 1.31463769 |
| 32 | MP0002272_abnormal_nervous_system | 1.30758090 |
| 33 | MP0000631_abnormal_neuroendocrine_gland | 1.30311524 |
| 34 | MP0002160_abnormal_reproductive_system | 1.30053992 |
| 35 | MP0001486_abnormal_startle_reflex | 1.29868445 |
| 36 | MP0004036_abnormal_muscle_relaxation | 1.27191987 |
| 37 | MP0005076_abnormal_cell_differentiation | 1.24912882 |
| 38 | MP0006292_abnormal_olfactory_placode | 1.23837056 |
| 39 | MP0003866_abnormal_defecation | 1.21275515 |
| 40 | MP0002751_abnormal_autonomic_nervous | 1.19223681 |
| 41 | MP0005389_reproductive_system_phenotype | 1.19004359 |
| 42 | MP0000685_abnormal_immune_system | 1.18347506 |
| 43 | MP0001119_abnormal_female_reproductive | 1.14000256 |
| 44 | MP0001929_abnormal_gametogenesis | 1.13866429 |
| 45 | MP0001177_atelectasis | 1.12277952 |
| 46 | MP0009745_abnormal_behavioral_response | 1.08589549 |
| 47 | MP0002210_abnormal_sex_determination | 1.07444501 |
| 48 | MP0001542_abnormal_bone_strength | 1.04156863 |
| 49 | MP0008775_abnormal_heart_ventricle | 1.04104944 |
| 50 | MP0008058_abnormal_DNA_repair | 1.04006694 |
| 51 | MP0005083_abnormal_biliary_tract | 1.01421806 |
| 52 | MP0002067_abnormal_sensory_capabilities | 0.98606339 |
| 53 | MP0005647_abnormal_sex_gland | 0.97577084 |
| 54 | MP0006072_abnormal_retinal_apoptosis | 0.97099505 |
| 55 | MP0005220_abnormal_exocrine_pancreas | 0.96420624 |
| 56 | MP0003136_yellow_coat_color | 0.96203194 |
| 57 | MP0002009_preneoplasia | 0.95929168 |
| 58 | MP0005551_abnormal_eye_electrophysiolog | 0.95311707 |
| 59 | MP0003938_abnormal_ear_development | 0.94789273 |
| 60 | MP0003936_abnormal_reproductive_system | 0.94708786 |
| 61 | MP0003385_abnormal_body_wall | 0.94194189 |
| 62 | MP0003828_pulmonary_edema | 0.93961180 |
| 63 | MP0005394_taste/olfaction_phenotype | 0.93678530 |
| 64 | MP0005499_abnormal_olfactory_system | 0.93678530 |
| 65 | MP0004924_abnormal_behavior | 0.92915624 |
| 66 | MP0005386_behavior/neurological_phenoty | 0.92915624 |
| 67 | MP0000639_abnormal_adrenal_gland | 0.90278012 |
| 68 | MP0004233_abnormal_muscle_weight | 0.89364669 |
| 69 | MP0002557_abnormal_social/conspecific_i | 0.89110695 |
| 70 | MP0005451_abnormal_body_composition | 0.88815074 |
| 71 | MP0000653_abnormal_sex_gland | 0.87658524 |
| 72 | MP0002075_abnormal_coat/hair_pigmentati | 0.87076320 |
| 73 | MP0003115_abnormal_respiratory_system | 0.86972801 |
| 74 | MP0003878_abnormal_ear_physiology | 0.86794535 |
| 75 | MP0005377_hearing/vestibular/ear_phenot | 0.86794535 |
| 76 | MP0008877_abnormal_DNA_methylation | 0.86436367 |
| 77 | MP0001919_abnormal_reproductive_system | 0.83929855 |
| 78 | MP0003890_abnormal_embryonic-extraembry | 0.83843468 |
| 79 | MP0001485_abnormal_pinna_reflex | 0.83259252 |
| 80 | MP0001963_abnormal_hearing_physiology | 0.82346490 |
| 81 | MP0003183_abnormal_peptide_metabolism | 0.82037448 |
| 82 | MP0003880_abnormal_central_pattern | 0.81453587 |
| 83 | MP0000733_abnormal_muscle_development | 0.80329388 |
| 84 | MP0003755_abnormal_palate_morphology | 0.80315778 |
| 85 | MP0002277_abnormal_respiratory_mucosa | 0.79880598 |
| 86 | MP0000778_abnormal_nervous_system | 0.79372557 |
| 87 | MP0000703_abnormal_thymus_morphology | 0.77404889 |
| 88 | MP0002095_abnormal_skin_pigmentation | 0.77368356 |
| 89 | MP0002938_white_spotting | 0.76839057 |
| 90 | MP0000613_abnormal_salivary_gland | 0.76048439 |
| 91 | MP0003635_abnormal_synaptic_transmissio | 0.74861687 |
| 92 | MP0000751_myopathy | 0.74043807 |
| 93 | MP0001340_abnormal_eyelid_morphology | 0.73939061 |
| 94 | MP0002572_abnormal_emotion/affect_behav | 0.73039053 |
| 95 | MP0003787_abnormal_imprinting | 0.72789838 |
| 96 | MP0003283_abnormal_digestive_organ | 0.72354778 |
| 97 | MP0001800_abnormal_humoral_immune | 0.71172469 |
| 98 | MP0003693_abnormal_embryo_hatching | 0.71108778 |
| 99 | MP0009697_abnormal_copulation | 0.69575877 |
| 100 | MP0005410_abnormal_fertilization | 0.69436137 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Bilateral sensorineural hearing impairment (HP:0008619) | 5.26599286 |
| 2 | Aplasia cutis congenita (HP:0001057) | 5.01271135 |
| 3 | Acute lymphatic leukemia (HP:0006721) | 4.91460234 |
| 4 | Gaze-evoked nystagmus (HP:0000640) | 4.83009728 |
| 5 | Fair hair (HP:0002286) | 4.66555668 |
| 6 | Skull defect (HP:0001362) | 4.39719537 |
| 7 | Autoimmune hemolytic anemia (HP:0001890) | 4.23303259 |
| 8 | Abnormal hair whorl (HP:0010721) | 3.96301180 |
| 9 | Rectovaginal fistula (HP:0000143) | 3.85142072 |
| 10 | Rectal fistula (HP:0100590) | 3.85142072 |
| 11 | Abnormality of dentin (HP:0010299) | 3.64598338 |
| 12 | Hyperventilation (HP:0002883) | 3.63470546 |
| 13 | Tinnitus (HP:0000360) | 3.48408758 |
| 14 | Intestinal fistula (HP:0100819) | 3.48340886 |
| 15 | Generalized hypopigmentation of hair (HP:0011358) | 3.25650447 |
| 16 | Septate vagina (HP:0001153) | 3.11086994 |
| 17 | Adactyly (HP:0009776) | 3.10151933 |
| 18 | Vaginal fistula (HP:0004320) | 3.06506130 |
| 19 | Hypoproteinemia (HP:0003075) | 3.04399391 |
| 20 | Hypoplastic nipples (HP:0002557) | 3.03756651 |
| 21 | Pancreatic fibrosis (HP:0100732) | 3.02637894 |
| 22 | Recurrent bronchitis (HP:0002837) | 2.99613210 |
| 23 | Curly hair (HP:0002212) | 2.97434607 |
| 24 | Febrile seizures (HP:0002373) | 2.94956729 |
| 25 | B lymphocytopenia (HP:0010976) | 2.94610296 |
| 26 | Focal motor seizures (HP:0011153) | 2.88394749 |
| 27 | Birth length less than 3rd percentile (HP:0003561) | 2.77116232 |
| 28 | Concave nail (HP:0001598) | 2.77105456 |
| 29 | Widely spaced teeth (HP:0000687) | 2.74946810 |
| 30 | Autoimmune thrombocytopenia (HP:0001973) | 2.66890694 |
| 31 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.65906027 |
| 32 | Facial cleft (HP:0002006) | 2.63993007 |
| 33 | Atonic seizures (HP:0010819) | 2.63495897 |
| 34 | Molar tooth sign on MRI (HP:0002419) | 2.63059427 |
| 35 | Abnormality of midbrain morphology (HP:0002418) | 2.63059427 |
| 36 | Abnormality of incisor morphology (HP:0011063) | 2.61974014 |
| 37 | Horizontal nystagmus (HP:0000666) | 2.58790217 |
| 38 | Cortical visual impairment (HP:0100704) | 2.55104332 |
| 39 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.53681071 |
| 40 | Abnormality of the dental pulp (HP:0006479) | 2.51682287 |
| 41 | Volvulus (HP:0002580) | 2.48929100 |
| 42 | Abnormality of B cell number (HP:0010975) | 2.43202923 |
| 43 | Congenital hepatic fibrosis (HP:0002612) | 2.42218587 |
| 44 | Short tibia (HP:0005736) | 2.35987514 |
| 45 | Aplasia/Hypoplasia of the nipples (HP:0006709) | 2.35670114 |
| 46 | Abnormality of the incisor (HP:0000676) | 2.35435233 |
| 47 | Hyperlipoproteinemia (HP:0010980) | 2.33690583 |
| 48 | Pancreatic cysts (HP:0001737) | 2.33626090 |
| 49 | Abnormality of the nasolacrimal system (HP:0000614) | 2.31481778 |
| 50 | Median cleft lip (HP:0000161) | 2.26096339 |
| 51 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.25204268 |
| 52 | Tubular atrophy (HP:0000092) | 2.21295179 |
| 53 | Nephronophthisis (HP:0000090) | 2.20486834 |
| 54 | Bowel diverticulosis (HP:0005222) | 2.16912264 |
| 55 | Deep philtrum (HP:0002002) | 2.15529200 |
| 56 | Hypochromic microcytic anemia (HP:0004840) | 2.11012465 |
| 57 | Tubulointerstitial fibrosis (HP:0005576) | 2.08475601 |
| 58 | Cubitus valgus (HP:0002967) | 2.07399272 |
| 59 | Flat occiput (HP:0005469) | 2.05107293 |
| 60 | Preaxial hand polydactyly (HP:0001177) | 2.03739601 |
| 61 | Porencephaly (HP:0002132) | 2.03732958 |
| 62 | Cystic hygroma (HP:0000476) | 2.03635805 |
| 63 | Progressive cerebellar ataxia (HP:0002073) | 2.01847392 |
| 64 | Abnormality of the renal medulla (HP:0100957) | 2.01576553 |
| 65 | True hermaphroditism (HP:0010459) | 2.00196619 |
| 66 | Focal seizures (HP:0007359) | 2.00166116 |
| 67 | Relative macrocephaly (HP:0004482) | 1.93978437 |
| 68 | Intestinal atresia (HP:0011100) | 1.93170141 |
| 69 | Inappropriate behavior (HP:0000719) | 1.89368146 |
| 70 | Long nose (HP:0003189) | 1.89009285 |
| 71 | Hyperglycinemia (HP:0002154) | 1.86969924 |
| 72 | Low anterior hairline (HP:0000294) | 1.84692241 |
| 73 | Keratoconus (HP:0000563) | 1.82833813 |
| 74 | Increased corneal curvature (HP:0100692) | 1.82833813 |
| 75 | Anteriorly placed anus (HP:0001545) | 1.82053403 |
| 76 | Drooling (HP:0002307) | 1.80858063 |
| 77 | Chronic hepatic failure (HP:0100626) | 1.80190683 |
| 78 | Submucous cleft hard palate (HP:0000176) | 1.78444212 |
| 79 | Epileptic encephalopathy (HP:0200134) | 1.77761096 |
| 80 | Abnormality of the pons (HP:0007361) | 1.76193556 |
| 81 | 2-3 toe syndactyly (HP:0004691) | 1.75061368 |
| 82 | Glioma (HP:0009733) | 1.74746639 |
| 83 | Portal hypertension (HP:0001409) | 1.74593551 |
| 84 | Agammaglobulinemia (HP:0004432) | 1.73762651 |
| 85 | Thickened helices (HP:0000391) | 1.73054541 |
| 86 | Abnormality of the antihelix (HP:0009738) | 1.71809331 |
| 87 | Excessive salivation (HP:0003781) | 1.71070207 |
| 88 | Bronchitis (HP:0012387) | 1.69501503 |
| 89 | Short ribs (HP:0000773) | 1.67025637 |
| 90 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.66916532 |
| 91 | Bifid tongue (HP:0010297) | 1.66786540 |
| 92 | Clitoromegaly (HP:0000057) | 1.66562615 |
| 93 | Narrow forehead (HP:0000341) | 1.66130170 |
| 94 | Cystic liver disease (HP:0006706) | 1.65773280 |
| 95 | Panhypogammaglobulinemia (HP:0003139) | 1.64886719 |
| 96 | Exocrine pancreatic insufficiency (HP:0001738) | 1.64619105 |
| 97 | Highly arched eyebrow (HP:0002553) | 1.64209998 |
| 98 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.64157442 |
| 99 | Tapered finger (HP:0001182) | 1.63026659 |
| 100 | Abnormality of T cell physiology (HP:0011840) | 1.61343691 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCR | 4.64215474 |
| 2 | PKN1 | 4.52724401 |
| 3 | BRSK2 | 4.27841683 |
| 4 | ZAK | 2.92129199 |
| 5 | PIK3CA | 2.81747461 |
| 6 | EPHA3 | 2.75152848 |
| 7 | VRK1 | 2.65181798 |
| 8 | MAP3K10 | 2.47325997 |
| 9 | CDK12 | 2.33426206 |
| 10 | MAP3K4 | 2.23487600 |
| 11 | MKNK2 | 2.15362209 |
| 12 | BRD4 | 2.09274597 |
| 13 | MARK3 | 2.06859161 |
| 14 | TLK1 | 1.87718267 |
| 15 | MAP3K9 | 1.86231637 |
| 16 | BRSK1 | 1.83495844 |
| 17 | TRIM28 | 1.80569421 |
| 18 | PLK4 | 1.68731627 |
| 19 | MKNK1 | 1.66915061 |
| 20 | SIK3 | 1.55788705 |
| 21 | IRAK1 | 1.55252913 |
| 22 | PAK3 | 1.53875061 |
| 23 | MAPK13 | 1.43962008 |
| 24 | STK16 | 1.39351301 |
| 25 | EIF2AK3 | 1.28135339 |
| 26 | MAP3K6 | 1.25484743 |
| 27 | EEF2K | 1.24303151 |
| 28 | EPHA4 | 1.22698404 |
| 29 | CDC7 | 1.16717372 |
| 30 | CHEK2 | 1.15710846 |
| 31 | TNIK | 1.15219248 |
| 32 | KSR2 | 1.10018804 |
| 33 | TSSK6 | 1.07959497 |
| 34 | PTK2B | 1.07352999 |
| 35 | FRK | 1.05776266 |
| 36 | SRPK1 | 1.01917589 |
| 37 | RAF1 | 0.99094042 |
| 38 | PRKCQ | 0.98072934 |
| 39 | STK3 | 0.95097400 |
| 40 | PIK3CG | 0.92213989 |
| 41 | CAMKK2 | 0.88247212 |
| 42 | NEK9 | 0.87191870 |
| 43 | CDK3 | 0.84712241 |
| 44 | MELK | 0.81665436 |
| 45 | MAPKAPK2 | 0.81462682 |
| 46 | MAP3K13 | 0.77239180 |
| 47 | BRAF | 0.77067188 |
| 48 | WNK3 | 0.77034190 |
| 49 | ARAF | 0.74888282 |
| 50 | AKT3 | 0.74493342 |
| 51 | PLK3 | 0.73313927 |
| 52 | SGK2 | 0.73197844 |
| 53 | CAMK1 | 0.71680757 |
| 54 | STK4 | 0.68393058 |
| 55 | MOS | 0.68186185 |
| 56 | CDK8 | 0.67342158 |
| 57 | RET | 0.65549152 |
| 58 | MAPK8 | 0.64233387 |
| 59 | CDK1 | 0.63831201 |
| 60 | CDK7 | 0.62902492 |
| 61 | KSR1 | 0.62800239 |
| 62 | RPS6KB1 | 0.62638331 |
| 63 | AURKA | 0.61747706 |
| 64 | RPS6KA5 | 0.60939108 |
| 65 | NTRK2 | 0.59687780 |
| 66 | ATR | 0.57312952 |
| 67 | ERBB3 | 0.55885337 |
| 68 | IRAK4 | 0.55837663 |
| 69 | MAP2K4 | 0.55075494 |
| 70 | MAP2K7 | 0.53953651 |
| 71 | CAMK4 | 0.52987299 |
| 72 | SIK2 | 0.52481604 |
| 73 | CHEK1 | 0.52444926 |
| 74 | PLK1 | 0.52241862 |
| 75 | FGFR3 | 0.51437790 |
| 76 | ATM | 0.51432239 |
| 77 | DYRK3 | 0.51123557 |
| 78 | CDK2 | 0.50503338 |
| 79 | TAOK3 | 0.50168154 |
| 80 | GSK3B | 0.49831832 |
| 81 | PRKCD | 0.49355550 |
| 82 | CSNK1D | 0.47896222 |
| 83 | CAMK1D | 0.47492680 |
| 84 | MINK1 | 0.44710522 |
| 85 | NEK6 | 0.42117509 |
| 86 | NLK | 0.41981346 |
| 87 | YES1 | 0.38213294 |
| 88 | CDK5 | 0.37310791 |
| 89 | PDGFRB | 0.37288985 |
| 90 | FER | 0.35542687 |
| 91 | SYK | 0.34613180 |
| 92 | MAP3K8 | 0.33718847 |
| 93 | MAPK11 | 0.32619767 |
| 94 | BUB1 | 0.32201948 |
| 95 | ROCK1 | 0.31554317 |
| 96 | CDK9 | 0.31549034 |
| 97 | SGK3 | 0.31519913 |
| 98 | RIPK4 | 0.31254276 |
| 99 | MAP2K1 | 0.31248390 |
| 100 | TNK2 | 0.30907312 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 4.48868722 |
| 2 | Alcoholism_Homo sapiens_hsa05034 | 3.48256533 |
| 3 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.95947627 |
| 4 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.53117751 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.43930554 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.35596406 |
| 7 | Lysine degradation_Homo sapiens_hsa00310 | 2.32184763 |
| 8 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.19298448 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.07321411 |
| 10 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.05589116 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.97538296 |
| 12 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.66997968 |
| 13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.66882439 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.65289966 |
| 15 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.64377337 |
| 16 | Asthma_Homo sapiens_hsa05310 | 1.60975290 |
| 17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.60879789 |
| 18 | Cell cycle_Homo sapiens_hsa04110 | 1.57503148 |
| 19 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.54329895 |
| 20 | Mismatch repair_Homo sapiens_hsa03430 | 1.50210987 |
| 21 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.46585332 |
| 22 | DNA replication_Homo sapiens_hsa03030 | 1.35277407 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.26459764 |
| 24 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.23711384 |
| 25 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.23645357 |
| 26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.22890576 |
| 27 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.14171409 |
| 28 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.11223556 |
| 29 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.07976382 |
| 30 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.05241407 |
| 31 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.04138787 |
| 32 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.03568209 |
| 33 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.03241700 |
| 34 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.01761359 |
| 35 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.00101183 |
| 36 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.98878282 |
| 37 | RNA degradation_Homo sapiens_hsa03018 | 0.98640097 |
| 38 | Base excision repair_Homo sapiens_hsa03410 | 0.97382581 |
| 39 | Melanoma_Homo sapiens_hsa05218 | 0.93687075 |
| 40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.93377753 |
| 41 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.93145608 |
| 42 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.92164947 |
| 43 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.88647318 |
| 44 | Long-term depression_Homo sapiens_hsa04730 | 0.85678725 |
| 45 | Glioma_Homo sapiens_hsa05214 | 0.81711934 |
| 46 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.79889479 |
| 47 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.77957123 |
| 48 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.77290129 |
| 49 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.76472607 |
| 50 | Leishmaniasis_Homo sapiens_hsa05140 | 0.75888337 |
| 51 | Long-term potentiation_Homo sapiens_hsa04720 | 0.74171257 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74011060 |
| 53 | Hepatitis B_Homo sapiens_hsa05161 | 0.73911652 |
| 54 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.73500306 |
| 55 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.73366539 |
| 56 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.71364190 |
| 57 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.68802210 |
| 58 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.68566083 |
| 59 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.68353165 |
| 60 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.67428727 |
| 61 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.66643014 |
| 62 | Spliceosome_Homo sapiens_hsa03040 | 0.65362695 |
| 63 | Measles_Homo sapiens_hsa05162 | 0.64973466 |
| 64 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.63244030 |
| 65 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.61819790 |
| 66 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.61537351 |
| 67 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.61283612 |
| 68 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.59991698 |
| 69 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.58971456 |
| 70 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.57284376 |
| 71 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55857875 |
| 72 | RNA transport_Homo sapiens_hsa03013 | 0.53951922 |
| 73 | HTLV-I infection_Homo sapiens_hsa05166 | 0.53752152 |
| 74 | Apoptosis_Homo sapiens_hsa04210 | 0.53736283 |
| 75 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.53290516 |
| 76 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.53051588 |
| 77 | Nicotine addiction_Homo sapiens_hsa05033 | 0.52581057 |
| 78 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.51707660 |
| 79 | Influenza A_Homo sapiens_hsa05164 | 0.50858839 |
| 80 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.50680486 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.50470414 |
| 82 | Circadian rhythm_Homo sapiens_hsa04710 | 0.50031063 |
| 83 | Colorectal cancer_Homo sapiens_hsa05210 | 0.48850352 |
| 84 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.48000434 |
| 85 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.47903624 |
| 86 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.47629583 |
| 87 | Phototransduction_Homo sapiens_hsa04744 | 0.45689258 |
| 88 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.45296083 |
| 89 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.45140721 |
| 90 | Olfactory transduction_Homo sapiens_hsa04740 | 0.43035118 |
| 91 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.41600246 |
| 92 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.41197549 |
| 93 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.40865969 |
| 94 | Viral myocarditis_Homo sapiens_hsa05416 | 0.39281390 |
| 95 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.38622518 |
| 96 | Bladder cancer_Homo sapiens_hsa05219 | 0.38106253 |
| 97 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.37447156 |
| 98 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.37188437 |
| 99 | Cocaine addiction_Homo sapiens_hsa05030 | 0.36932507 |
| 100 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.36912855 |

