Rank | Gene Set | Z-score |
---|---|---|
1 | establishment of integrated proviral latency (GO:0075713) | 4.73954926 |
2 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 4.45657224 |
3 | CENP-A containing nucleosome assembly (GO:0034080) | 4.21620876 |
4 | mitotic metaphase plate congression (GO:0007080) | 4.18925567 |
5 | chromatin remodeling at centromere (GO:0031055) | 4.15712704 |
6 | ribosome assembly (GO:0042255) | 4.11373319 |
7 | kinetochore organization (GO:0051383) | 4.09628598 |
8 | DNA topological change (GO:0006265) | 4.05460722 |
9 | DNA replication checkpoint (GO:0000076) | 4.01166379 |
10 | DNA replication initiation (GO:0006270) | 3.98025916 |
11 | ribosomal small subunit assembly (GO:0000028) | 3.95677234 |
12 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.95659157 |
13 | regulation of translational fidelity (GO:0006450) | 3.93771009 |
14 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.92777882 |
15 | non-recombinational repair (GO:0000726) | 3.86962833 |
16 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.86962833 |
17 | proteasome assembly (GO:0043248) | 3.84615029 |
18 | nuclear pore complex assembly (GO:0051292) | 3.83711271 |
19 | formation of translation preinitiation complex (GO:0001731) | 3.81940457 |
20 | DNA strand elongation (GO:0022616) | 3.80427329 |
21 | telomere maintenance via recombination (GO:0000722) | 3.77683238 |
22 | kinetochore assembly (GO:0051382) | 3.72311859 |
23 | metaphase plate congression (GO:0051310) | 3.72208082 |
24 | meiotic chromosome segregation (GO:0045132) | 3.72111826 |
25 | nuclear pore organization (GO:0006999) | 3.71334532 |
26 | regulation of chromosome segregation (GO:0051983) | 3.70034386 |
27 | positive regulation of chromosome segregation (GO:0051984) | 3.66443918 |
28 | nucleobase biosynthetic process (GO:0046112) | 3.62212415 |
29 | mitotic recombination (GO:0006312) | 3.61876697 |
30 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.61585664 |
31 | DNA replication-independent nucleosome organization (GO:0034724) | 3.61585664 |
32 | purine nucleobase biosynthetic process (GO:0009113) | 3.59785535 |
33 | histone exchange (GO:0043486) | 3.57609771 |
34 | DNA duplex unwinding (GO:0032508) | 3.57200055 |
35 | protein K6-linked ubiquitination (GO:0085020) | 3.56488928 |
36 | chromosome condensation (GO:0030261) | 3.54601801 |
37 | heterochromatin organization (GO:0070828) | 3.54491412 |
38 | regulation of mitotic spindle organization (GO:0060236) | 3.54290794 |
39 | establishment of chromosome localization (GO:0051303) | 3.52346284 |
40 | maturation of 5.8S rRNA (GO:0000460) | 3.51615717 |
41 | protein localization to kinetochore (GO:0034501) | 3.49609453 |
42 | IMP biosynthetic process (GO:0006188) | 3.49277088 |
43 | regulation of sister chromatid cohesion (GO:0007063) | 3.49240837 |
44 | DNA geometric change (GO:0032392) | 3.46740566 |
45 | establishment of viral latency (GO:0019043) | 3.44676558 |
46 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.44116624 |
47 | regulation of centriole replication (GO:0046599) | 3.41696503 |
48 | mitotic spindle assembly checkpoint (GO:0007094) | 3.40453225 |
49 | * chromosome segregation (GO:0007059) | 3.39696587 |
50 | maturation of SSU-rRNA (GO:0030490) | 3.38689561 |
51 | regulation of DNA endoreduplication (GO:0032875) | 3.35332372 |
52 | telomere maintenance via telomere lengthening (GO:0010833) | 3.30778540 |
53 | DNA ligation (GO:0006266) | 3.28529867 |
54 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.27588258 |
55 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.27427734 |
56 | mitotic nuclear envelope disassembly (GO:0007077) | 3.27037929 |
57 | * DNA conformation change (GO:0071103) | 3.26839638 |
58 | microtubule depolymerization (GO:0007019) | 3.23721984 |
59 | mitotic sister chromatid segregation (GO:0000070) | 3.23090480 |
60 | nuclear envelope organization (GO:0006998) | 3.21605560 |
61 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.20002870 |
62 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.19154660 |
63 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.19154660 |
64 | regulation of centrosome cycle (GO:0046605) | 3.18136865 |
65 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.17928101 |
66 | DNA deamination (GO:0045006) | 3.17540888 |
67 | chromatin assembly or disassembly (GO:0006333) | 3.17086612 |
68 | cellular protein complex localization (GO:0034629) | 3.16473820 |
69 | protein localization to chromosome, centromeric region (GO:0071459) | 3.16248501 |
70 | protein complex localization (GO:0031503) | 3.14973549 |
71 | protein localization to chromosome (GO:0034502) | 3.14206186 |
72 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.13906725 |
73 | mitotic G2/M transition checkpoint (GO:0044818) | 3.11669688 |
74 | pore complex assembly (GO:0046931) | 3.11545896 |
75 | * DNA packaging (GO:0006323) | 3.10521666 |
76 | regulation of RNA export from nucleus (GO:0046831) | 3.09981136 |
77 | spindle checkpoint (GO:0031577) | 3.09676611 |
78 | pre-miRNA processing (GO:0031054) | 3.08600796 |
79 | ribosome biogenesis (GO:0042254) | 3.04830110 |
80 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.04141969 |
81 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.02873553 |
82 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.02873553 |
83 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.02873553 |
84 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.02553994 |
85 | RNA-dependent DNA replication (GO:0006278) | 3.02364842 |
86 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.01708952 |
87 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.01708952 |
88 | rRNA modification (GO:0000154) | 3.00176326 |
89 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.99687553 |
90 | DNA synthesis involved in DNA repair (GO:0000731) | 2.98596448 |
91 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.98278578 |
92 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.97430491 |
93 | membrane disassembly (GO:0030397) | 2.97292091 |
94 | nuclear envelope disassembly (GO:0051081) | 2.97292091 |
95 | tRNA aminoacylation for protein translation (GO:0006418) | 2.96637577 |
96 | termination of RNA polymerase I transcription (GO:0006363) | 2.96395942 |
97 | DNA double-strand break processing (GO:0000729) | 2.96277763 |
98 | mismatch repair (GO:0006298) | 2.95932971 |
99 | viral mRNA export from host cell nucleus (GO:0046784) | 2.95927019 |
100 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.95506168 |
101 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.94851032 |
102 | ribosomal large subunit biogenesis (GO:0042273) | 2.92273556 |
103 | IMP metabolic process (GO:0046040) | 2.90793340 |
104 | mitotic sister chromatid cohesion (GO:0007064) | 2.90572053 |
105 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.89954133 |
106 | negative regulation of sister chromatid segregation (GO:0033046) | 2.89954133 |
107 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.89954133 |
108 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.89954133 |
109 | histone H2A acetylation (GO:0043968) | 2.89090210 |
110 | regulation of spindle organization (GO:0090224) | 2.89051772 |
111 | mitotic spindle checkpoint (GO:0071174) | 2.88772758 |
112 | telomere maintenance (GO:0000723) | 2.88757700 |
113 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.88509065 |
114 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.88271539 |
115 | negative regulation of chromosome segregation (GO:0051985) | 2.87546968 |
116 | 7-methylguanosine mRNA capping (GO:0006370) | 2.87483781 |
117 | transcription from RNA polymerase I promoter (GO:0006360) | 2.87402965 |
118 | 7-methylguanosine RNA capping (GO:0009452) | 2.86722642 |
119 | RNA capping (GO:0036260) | 2.86722642 |
120 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.86531404 |
121 | telomere organization (GO:0032200) | 2.85822445 |
122 | DNA-dependent DNA replication (GO:0006261) | 2.85674829 |
123 | mitotic chromosome condensation (GO:0007076) | 2.84684099 |
124 | DNA replication (GO:0006260) | 2.84439177 |
125 | ATP-dependent chromatin remodeling (GO:0043044) | 2.83921865 |
126 | intra-S DNA damage checkpoint (GO:0031573) | 2.83745375 |
127 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.83682132 |
128 | sister chromatid segregation (GO:0000819) | 2.82339267 |
129 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.81762646 |
130 | spliceosomal snRNP assembly (GO:0000387) | 2.80604131 |
131 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 2.80263241 |
132 | replication fork processing (GO:0031297) | 2.79272094 |
133 | spindle assembly checkpoint (GO:0071173) | 2.79184905 |
134 | sister chromatid cohesion (GO:0007062) | 2.78641451 |
135 | pseudouridine synthesis (GO:0001522) | 2.77901918 |
136 | DNA unwinding involved in DNA replication (GO:0006268) | 2.77548962 |
137 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.77446328 |
138 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.77446328 |
139 | inner cell mass cell proliferation (GO:0001833) | 2.77435228 |
140 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.77350708 |
141 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.77350708 |
142 | regulation of sister chromatid segregation (GO:0033045) | 2.77350708 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.96534101 |
2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.23630054 |
3 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.64536879 |
4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.62475595 |
5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.59065054 |
6 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.46013803 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.21299168 |
8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.76562971 |
9 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.66987179 |
10 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.64882062 |
11 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.57158852 |
12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.54662132 |
13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.45871986 |
14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.43372491 |
15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.42656670 |
16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.41100823 |
17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.39054039 |
18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.38163638 |
19 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.33918854 |
20 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.28028020 |
21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.26836129 |
22 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.22863959 |
23 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.20097989 |
24 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.19444548 |
25 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.16396011 |
26 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.14204225 |
27 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.11248929 |
28 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.08847200 |
29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.07368050 |
30 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.06735384 |
31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04131736 |
32 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.01688039 |
33 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.95261267 |
34 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.93505147 |
35 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.87227054 |
36 | * PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.84074071 |
37 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.79853899 |
38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.76227226 |
39 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.75481201 |
40 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.73681844 |
41 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.73264017 |
42 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.72751835 |
43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.69310234 |
44 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.66530550 |
45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.65969845 |
46 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.65941203 |
47 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.64234775 |
48 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63491912 |
49 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.60144556 |
50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.58793663 |
51 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.51153560 |
52 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.50736259 |
53 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.47986436 |
54 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.47029835 |
55 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.44291912 |
56 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.39345623 |
57 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.35589012 |
58 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.32729632 |
59 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.32354650 |
60 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.32213058 |
61 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.29691126 |
62 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.28372563 |
63 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.27830323 |
64 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.26888002 |
65 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.23865315 |
66 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18046888 |
67 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.17318599 |
68 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17243040 |
69 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.15412515 |
70 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.13129475 |
71 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.12068057 |
72 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10694179 |
73 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.10017881 |
74 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.10003266 |
75 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.09892804 |
76 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08448993 |
77 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.06473754 |
78 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.01083738 |
79 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.01046714 |
80 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.99864036 |
81 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.99545467 |
82 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99481053 |
83 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.97547715 |
84 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.97430207 |
85 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.93746553 |
86 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.91999206 |
87 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.90080895 |
88 | EWS_26573619_Chip-Seq_HEK293_Human | 0.89998450 |
89 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.87600823 |
90 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.86605278 |
91 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.86308718 |
92 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.84400226 |
93 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.83232072 |
94 | * TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.81710138 |
95 | * KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.81651697 |
96 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.81017841 |
97 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.81014448 |
98 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.80775509 |
99 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.80128665 |
100 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.79673955 |
101 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.77756225 |
102 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.77243529 |
103 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.75506726 |
104 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.74395006 |
105 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.73969264 |
106 | FUS_26573619_Chip-Seq_HEK293_Human | 0.73212332 |
107 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.73185623 |
108 | * FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.71566222 |
109 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.69241384 |
110 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.69141634 |
111 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.68625011 |
112 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.65857955 |
113 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.64966552 |
114 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.64385968 |
115 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.64281997 |
116 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.63350400 |
117 | MYC_22102868_ChIP-Seq_BL_Human | 0.63248807 |
118 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.63204722 |
119 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.62943997 |
120 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.62039589 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 4.23169232 |
2 | MP0003693_abnormal_embryo_hatching | 4.18353838 |
3 | MP0008057_abnormal_DNA_replication | 4.02767778 |
4 | MP0008058_abnormal_DNA_repair | 3.60296170 |
5 | MP0003111_abnormal_nucleus_morphology | 3.55612257 |
6 | MP0008877_abnormal_DNA_methylation | 3.31028017 |
7 | MP0003077_abnormal_cell_cycle | 3.29533461 |
8 | MP0004957_abnormal_blastocyst_morpholog | 3.09616815 |
9 | MP0006292_abnormal_olfactory_placode | 3.00915946 |
10 | MP0008007_abnormal_cellular_replicative | 2.82189174 |
11 | MP0002396_abnormal_hematopoietic_system | 2.65029228 |
12 | MP0010352_gastrointestinal_tract_polyps | 2.50683196 |
13 | MP0003786_premature_aging | 2.20090836 |
14 | MP0008932_abnormal_embryonic_tissue | 2.17394600 |
15 | MP0001188_hyperpigmentation | 2.15689090 |
16 | MP0000566_synostosis | 2.06274307 |
17 | MP0002877_abnormal_melanocyte_morpholog | 1.87308522 |
18 | MP0003123_paternal_imprinting | 1.83948264 |
19 | MP0003763_abnormal_thymus_physiology | 1.80727151 |
20 | MP0003718_maternal_effect | 1.73642695 |
21 | MP0005075_abnormal_melanosome_morpholog | 1.70492017 |
22 | MP0003315_abnormal_perineum_morphology | 1.70129136 |
23 | MP0000015_abnormal_ear_pigmentation | 1.69711886 |
24 | MP0005409_darkened_coat_color | 1.65475750 |
25 | MP0010234_abnormal_vibrissa_follicle | 1.64188513 |
26 | MP0004808_abnormal_hematopoietic_stem | 1.64042958 |
27 | MP0000350_abnormal_cell_proliferation | 1.61100471 |
28 | MP0003136_yellow_coat_color | 1.60066760 |
29 | MP0002210_abnormal_sex_determination | 1.59700509 |
30 | MP0000490_abnormal_crypts_of | 1.55928154 |
31 | MP0004381_abnormal_hair_follicle | 1.52101558 |
32 | MP0003121_genomic_imprinting | 1.51749916 |
33 | MP0003941_abnormal_skin_development | 1.48987535 |
34 | MP0009697_abnormal_copulation | 1.45734287 |
35 | MP0001929_abnormal_gametogenesis | 1.41500308 |
36 | MP0001730_embryonic_growth_arrest | 1.39588366 |
37 | MP0003787_abnormal_imprinting | 1.39326731 |
38 | MP0003221_abnormal_cardiomyocyte_apopto | 1.38017235 |
39 | MP0005076_abnormal_cell_differentiation | 1.37863562 |
40 | MP0005174_abnormal_tail_pigmentation | 1.37815110 |
41 | MP0002095_abnormal_skin_pigmentation | 1.36683607 |
42 | MP0002160_abnormal_reproductive_system | 1.34563308 |
43 | MP0005408_hypopigmentation | 1.34247661 |
44 | MP0000537_abnormal_urethra_morphology | 1.31796679 |
45 | MP0001145_abnormal_male_reproductive | 1.25565128 |
46 | MP0010307_abnormal_tumor_latency | 1.25257014 |
47 | MP0009333_abnormal_splenocyte_physiolog | 1.24295858 |
48 | MP0001119_abnormal_female_reproductive | 1.22924010 |
49 | MP0002009_preneoplasia | 1.20528075 |
50 | MP0009379_abnormal_foot_pigmentation | 1.19143358 |
51 | MP0004185_abnormal_adipocyte_glucose | 1.18765341 |
52 | MP0001672_abnormal_embryogenesis/_devel | 1.18226656 |
53 | MP0005380_embryogenesis_phenotype | 1.18226656 |
54 | MP0000653_abnormal_sex_gland | 1.17942187 |
55 | MP0006035_abnormal_mitochondrial_morpho | 1.17526627 |
56 | MP0003806_abnormal_nucleotide_metabolis | 1.17418143 |
57 | MP0000372_irregular_coat_pigmentation | 1.15056340 |
58 | MP0000516_abnormal_urinary_system | 1.14498283 |
59 | MP0005367_renal/urinary_system_phenotyp | 1.14498283 |
60 | MP0001697_abnormal_embryo_size | 1.14145520 |
61 | MP0002697_abnormal_eye_size | 1.12156290 |
62 | MP0004233_abnormal_muscle_weight | 1.10657894 |
63 | MP0000313_abnormal_cell_death | 1.10299541 |
64 | MP0004264_abnormal_extraembryonic_tissu | 1.04828227 |
65 | MP0005389_reproductive_system_phenotype | 1.03828442 |
66 | MP0008789_abnormal_olfactory_epithelium | 1.03017910 |
67 | MP0003890_abnormal_embryonic-extraembry | 1.02895552 |
68 | MP0003943_abnormal_hepatobiliary_system | 1.00715972 |
69 | MP0000703_abnormal_thymus_morphology | 1.00301244 |
70 | MP0000358_abnormal_cell_content/ | 1.00019997 |
71 | MP0003566_abnormal_cell_adhesion | 0.99949050 |
72 | MP0002102_abnormal_ear_morphology | 0.99860173 |
73 | MP0002085_abnormal_embryonic_tissue | 0.99580231 |
74 | MP0002938_white_spotting | 0.99279020 |
75 | MP0005501_abnormal_skin_physiology | 0.98409368 |
76 | MP0002398_abnormal_bone_marrow | 0.97906424 |
77 | MP0003984_embryonic_growth_retardation | 0.97870367 |
78 | MP0002019_abnormal_tumor_incidence | 0.97688612 |
79 | MP0001293_anophthalmia | 0.97669065 |
80 | MP0003698_abnormal_male_reproductive | 0.97571252 |
81 | MP0002796_impaired_skin_barrier | 0.95867016 |
82 | MP0000428_abnormal_craniofacial_morphol | 0.94988460 |
83 | MP0002088_abnormal_embryonic_growth/wei | 0.94381404 |
84 | MP0003705_abnormal_hypodermis_morpholog | 0.93935742 |
85 | MP0004782_abnormal_surfactant_physiolog | 0.93290363 |
86 | MP0004197_abnormal_fetal_growth/weight/ | 0.92479986 |
87 | MP0002080_prenatal_lethality | 0.92228544 |
88 | MP0002111_abnormal_tail_morphology | 0.91856392 |
89 | MP0003385_abnormal_body_wall | 0.90468910 |
90 | MP0001919_abnormal_reproductive_system | 0.90350234 |
91 | MP0002234_abnormal_pharynx_morphology | 0.90173252 |
92 | MP0005451_abnormal_body_composition | 0.89816574 |
93 | MP0005384_cellular_phenotype | 0.89093774 |
94 | MP0002092_abnormal_eye_morphology | 0.88216449 |
95 | MP0003937_abnormal_limbs/digits/tail_de | 0.87493146 |
96 | MP0005671_abnormal_response_to | 0.86951001 |
97 | MP0005621_abnormal_cell_physiology | 0.86668141 |
98 | MP0002132_abnormal_respiratory_system | 0.85910392 |
99 | MP0001545_abnormal_hematopoietic_system | 0.85653206 |
100 | MP0005397_hematopoietic_system_phenotyp | 0.85653206 |
101 | MP0003567_abnormal_fetal_cardiomyocyte | 0.85267686 |
102 | MP0001286_abnormal_eye_development | 0.84322268 |
103 | MP0002233_abnormal_nose_morphology | 0.84265629 |
104 | MP0002084_abnormal_developmental_patter | 0.84242364 |
105 | MP0010030_abnormal_orbit_morphology | 0.83719095 |
106 | MP0000049_abnormal_middle_ear | 0.82637860 |
107 | MP0009053_abnormal_anal_canal | 0.81899967 |
108 | MP0002177_abnormal_outer_ear | 0.81744923 |
109 | MP0002277_abnormal_respiratory_mucosa | 0.81342511 |
110 | MP0009672_abnormal_birth_weight | 0.80302776 |
111 | MP0002751_abnormal_autonomic_nervous | 0.79950734 |
112 | MP0005171_absent_coat_pigmentation | 0.79764248 |
113 | MP0001186_pigmentation_phenotype | 0.79148372 |
114 | MP0008995_early_reproductive_senescence | 0.78618173 |
115 | MP0002722_abnormal_immune_system | 0.78584594 |
116 | MP0000689_abnormal_spleen_morphology | 0.78062232 |
117 | MP0002086_abnormal_extraembryonic_tissu | 0.76701753 |
118 | MP0001915_intracranial_hemorrhage | 0.76532619 |
119 | MP0005394_taste/olfaction_phenotype | 0.76378141 |
120 | MP0005499_abnormal_olfactory_system | 0.76378141 |
121 | MP0003950_abnormal_plasma_membrane | 0.76375111 |
122 | MP0003115_abnormal_respiratory_system | 0.75282270 |
123 | MP0003938_abnormal_ear_development | 0.74571860 |
124 | MP0005410_abnormal_fertilization | 0.73924981 |
125 | MP0003119_abnormal_digestive_system | 0.71621386 |
126 | MP0003936_abnormal_reproductive_system | 0.70833429 |
127 | MP0000647_abnormal_sebaceous_gland | 0.70800006 |
128 | MP0002006_tumorigenesis | 0.70417248 |
129 | MP0003699_abnormal_female_reproductive | 0.68827663 |
130 | MP0002075_abnormal_coat/hair_pigmentati | 0.68311684 |
131 | MP0002060_abnormal_skin_morphology | 0.68292843 |
132 | MP0000432_abnormal_head_morphology | 0.68056703 |
133 | MP0003861_abnormal_nervous_system | 0.67234238 |
134 | MP0002163_abnormal_gland_morphology | 0.67025206 |
135 | MP0001216_abnormal_epidermal_layer | 0.67000920 |
136 | MP0003935_abnormal_craniofacial_develop | 0.66785395 |
137 | MP0009703_decreased_birth_body | 0.66448172 |
138 | MP0002429_abnormal_blood_cell | 0.66057535 |
139 | MP0005395_other_phenotype | 0.65618476 |
140 | MP0000716_abnormal_immune_system | 0.65239042 |
141 | MP0001661_extended_life_span | 0.64829209 |
142 | MP0000762_abnormal_tongue_morphology | 0.58292299 |
143 | MP0010678_abnormal_skin_adnexa | 0.58008683 |
144 | MP0003755_abnormal_palate_morphology | 0.57333211 |
145 | MP0000579_abnormal_nail_morphology | 0.57268451 |
146 | MP0001346_abnormal_lacrimal_gland | 0.56942452 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromsome breakage (HP:0040012) | 4.90461371 |
2 | Birth length less than 3rd percentile (HP:0003561) | 4.70946397 |
3 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.67177379 |
4 | Increased nuchal translucency (HP:0010880) | 3.37352953 |
5 | Meckel diverticulum (HP:0002245) | 3.34707189 |
6 | Abnormality of the preputium (HP:0100587) | 3.25192884 |
7 | Abnormality of chromosome stability (HP:0003220) | 3.23061256 |
8 | Abnormality of the ileum (HP:0001549) | 3.17815223 |
9 | Ectopic kidney (HP:0000086) | 3.13776628 |
10 | Abnormal lung lobation (HP:0002101) | 3.09416790 |
11 | Breast hypoplasia (HP:0003187) | 3.07397581 |
12 | Patellar aplasia (HP:0006443) | 3.07154234 |
13 | 11 pairs of ribs (HP:0000878) | 3.01643387 |
14 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.93098136 |
15 | Reticulocytopenia (HP:0001896) | 2.91311218 |
16 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.90770974 |
17 | Impulsivity (HP:0100710) | 2.87464417 |
18 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.86061002 |
19 | Abnormality of glycolysis (HP:0004366) | 2.83300004 |
20 | Myelodysplasia (HP:0002863) | 2.80152086 |
21 | Deviation of the thumb (HP:0009603) | 2.73739517 |
22 | Cortical dysplasia (HP:0002539) | 2.68654922 |
23 | Proximal placement of thumb (HP:0009623) | 2.68557330 |
24 | Degeneration of anterior horn cells (HP:0002398) | 2.67230718 |
25 | Abnormality of the anterior horn cell (HP:0006802) | 2.67230718 |
26 | Embryonal renal neoplasm (HP:0011794) | 2.66978520 |
27 | Supernumerary spleens (HP:0009799) | 2.66489762 |
28 | Increased serum pyruvate (HP:0003542) | 2.63033909 |
29 | Aplastic anemia (HP:0001915) | 2.62813613 |
30 | Duodenal stenosis (HP:0100867) | 2.51763380 |
31 | Small intestinal stenosis (HP:0012848) | 2.51763380 |
32 | Carpal bone hypoplasia (HP:0001498) | 2.51249251 |
33 | Multiple enchondromatosis (HP:0005701) | 2.47696803 |
34 | Cafe-au-lait spot (HP:0000957) | 2.35324855 |
35 | Clubbing of toes (HP:0100760) | 2.35162364 |
36 | Absent thumb (HP:0009777) | 2.34962851 |
37 | Type I transferrin isoform profile (HP:0003642) | 2.34847255 |
38 | Short middle phalanx of the 5th finger (HP:0004220) | 2.34704617 |
39 | Abnormality of methionine metabolism (HP:0010901) | 2.30818390 |
40 | Absent radius (HP:0003974) | 2.30299901 |
41 | Abnormality of the fingertips (HP:0001211) | 2.29453443 |
42 | Bone marrow hypocellularity (HP:0005528) | 2.28755059 |
43 | Rhabdomyosarcoma (HP:0002859) | 2.28596470 |
44 | Acute myeloid leukemia (HP:0004808) | 2.27409401 |
45 | Ankyloglossia (HP:0010296) | 2.24101998 |
46 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.23890641 |
47 | Overlapping toe (HP:0001845) | 2.22369098 |
48 | Abnormality of the duodenum (HP:0002246) | 2.21888538 |
49 | Embryonal neoplasm (HP:0002898) | 2.21122246 |
50 | Sloping forehead (HP:0000340) | 2.18875470 |
51 | Medulloblastoma (HP:0002885) | 2.18839747 |
52 | Triphalangeal thumb (HP:0001199) | 2.17464864 |
53 | Abnormal number of erythroid precursors (HP:0012131) | 2.17101626 |
54 | Aplasia involving forearm bones (HP:0009822) | 2.15120673 |
55 | Absent forearm bone (HP:0003953) | 2.15120673 |
56 | Type 2 muscle fiber atrophy (HP:0003554) | 2.14517176 |
57 | Missing ribs (HP:0000921) | 2.13846890 |
58 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.13070310 |
59 | Abnormal foot bone ossification (HP:0010675) | 2.12658458 |
60 | Short thumb (HP:0009778) | 2.10082534 |
61 | Colon cancer (HP:0003003) | 2.09291148 |
62 | Choanal atresia (HP:0000453) | 2.07521659 |
63 | Progressive external ophthalmoplegia (HP:0000590) | 2.06923024 |
64 | Abnormality of the renal collecting system (HP:0004742) | 2.06424231 |
65 | Premature graying of hair (HP:0002216) | 2.05360779 |
66 | Intestinal fistula (HP:0100819) | 2.04300051 |
67 | Horseshoe kidney (HP:0000085) | 2.03301040 |
68 | Duplicated collecting system (HP:0000081) | 2.03057963 |
69 | Abnormality of the labia minora (HP:0012880) | 2.02648486 |
70 | Neoplasm of the colon (HP:0100273) | 2.01801386 |
71 | True hermaphroditism (HP:0010459) | 2.01322275 |
72 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.00871731 |
73 | Selective tooth agenesis (HP:0001592) | 2.00393684 |
74 | Insidious onset (HP:0003587) | 2.00022381 |
75 | Termporal pattern (HP:0011008) | 2.00022381 |
76 | Oral leukoplakia (HP:0002745) | 1.99294736 |
77 | Lip pit (HP:0100267) | 1.96227696 |
78 | Optic nerve coloboma (HP:0000588) | 1.95794735 |
79 | Abnormality of cochlea (HP:0000375) | 1.94264300 |
80 | Progressive muscle weakness (HP:0003323) | 1.93684901 |
81 | Volvulus (HP:0002580) | 1.93533766 |
82 | Microglossia (HP:0000171) | 1.93509854 |
83 | Abnormality of the carotid arteries (HP:0005344) | 1.93094819 |
84 | Cholecystitis (HP:0001082) | 1.92235197 |
85 | Abnormal gallbladder physiology (HP:0012438) | 1.92235197 |
86 | Abnormality of DNA repair (HP:0003254) | 1.91399698 |
87 | Cleft eyelid (HP:0000625) | 1.90351008 |
88 | High anterior hairline (HP:0009890) | 1.89296474 |
89 | Gastrointestinal carcinoma (HP:0002672) | 1.88745489 |
90 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.88745489 |
91 | Facial cleft (HP:0002006) | 1.88516624 |
92 | Macrocytic anemia (HP:0001972) | 1.87982392 |
93 | Abnormal spermatogenesis (HP:0008669) | 1.87436996 |
94 | Pancreatic fibrosis (HP:0100732) | 1.85895343 |
95 | Septate vagina (HP:0001153) | 1.85689543 |
96 | Sandal gap (HP:0001852) | 1.85653913 |
97 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.84514342 |
98 | Hypoplasia of the radius (HP:0002984) | 1.82074547 |
99 | Muscle fiber atrophy (HP:0100295) | 1.79507704 |
100 | Leiomyosarcoma (HP:0100243) | 1.79416253 |
101 | Uterine leiomyosarcoma (HP:0002891) | 1.79416253 |
102 | Premature ovarian failure (HP:0008209) | 1.78501533 |
103 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.78388779 |
104 | Preaxial hand polydactyly (HP:0001177) | 1.77779394 |
105 | Atresia of the external auditory canal (HP:0000413) | 1.73866763 |
106 | Anal stenosis (HP:0002025) | 1.73826105 |
107 | Rough bone trabeculation (HP:0100670) | 1.73653442 |
108 | Orthostatic hypotension (HP:0001278) | 1.72436729 |
109 | Spastic diplegia (HP:0001264) | 1.72417890 |
110 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.71873307 |
111 | Single umbilical artery (HP:0001195) | 1.71873307 |
112 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.71873307 |
113 | Ependymoma (HP:0002888) | 1.71661650 |
114 | Microvesicular hepatic steatosis (HP:0001414) | 1.71250713 |
115 | Arteriovenous malformation (HP:0100026) | 1.71172201 |
116 | Lymphoma (HP:0002665) | 1.70965434 |
117 | Thrombocytosis (HP:0001894) | 1.70426937 |
118 | Pulmonary fibrosis (HP:0002206) | 1.70222725 |
119 | Uterine neoplasm (HP:0010784) | 1.69878671 |
120 | Pallor (HP:0000980) | 1.69678320 |
121 | Papillary thyroid carcinoma (HP:0002895) | 1.68648633 |
122 | Poikiloderma (HP:0001029) | 1.68595492 |
123 | Rectovaginal fistula (HP:0000143) | 1.68409466 |
124 | Rectal fistula (HP:0100590) | 1.68409466 |
125 | Pancreatic cysts (HP:0001737) | 1.68222279 |
126 | Abnormal protein glycosylation (HP:0012346) | 1.67665625 |
127 | Abnormal glycosylation (HP:0012345) | 1.67665625 |
128 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.67665625 |
129 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.67665625 |
130 | Abnormal number of incisors (HP:0011064) | 1.66484843 |
131 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.65800130 |
132 | Diastasis recti (HP:0001540) | 1.65709948 |
133 | IgM deficiency (HP:0002850) | 1.65334194 |
134 | Median cleft lip (HP:0000161) | 1.64901380 |
135 | Neuroblastoma (HP:0003006) | 1.64757737 |
136 | Primitive neuroectodermal tumor (HP:0030065) | 1.64757737 |
137 | Neuroblastic tumors (HP:0004376) | 1.64757737 |
138 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.64757737 |
139 | Tracheoesophageal fistula (HP:0002575) | 1.64678067 |
140 | Abnormality of the columella (HP:0009929) | 1.63279225 |
141 | Capillary hemangiomas (HP:0005306) | 1.61928299 |
142 | Secondary amenorrhea (HP:0000869) | 1.61751567 |
143 | Biliary tract neoplasm (HP:0100574) | 1.61430061 |
144 | Pancytopenia (HP:0001876) | 1.61273701 |
145 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.61255020 |
146 | Neoplasm of the small intestine (HP:0100833) | 1.61021676 |
147 | Cellular immunodeficiency (HP:0005374) | 1.61005762 |
148 | Severe visual impairment (HP:0001141) | 1.60983784 |
149 | Microretrognathia (HP:0000308) | 1.60908801 |
150 | Squamous cell carcinoma (HP:0002860) | 1.60165452 |
151 | Adrenal hypoplasia (HP:0000835) | 1.59851002 |
152 | Megaloblastic anemia (HP:0001889) | 1.59495677 |
153 | Absent/shortened dynein arms (HP:0200106) | 1.59444053 |
154 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.59444053 |
155 | Ovarian neoplasm (HP:0100615) | 1.58489015 |
156 | Hypoplastic pelvis (HP:0008839) | 1.58217020 |
157 | Abnormality of homocysteine metabolism (HP:0010919) | 1.58051732 |
158 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.57515179 |
159 | Intestinal atresia (HP:0011100) | 1.56034546 |
160 | Deep philtrum (HP:0002002) | 1.55201947 |
161 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.53394766 |
162 | Agnosia (HP:0010524) | 1.53359502 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 3.76088744 |
2 | BUB1 | 3.25304391 |
3 | PBK | 3.19661205 |
4 | WEE1 | 3.06355483 |
5 | MKNK1 | 2.93740722 |
6 | PLK4 | 2.87582616 |
7 | MKNK2 | 2.86684712 |
8 | EIF2AK1 | 2.76790252 |
9 | TSSK6 | 2.31477013 |
10 | * SRPK1 | 2.30696922 |
11 | CASK | 2.29003816 |
12 | MUSK | 2.20711059 |
13 | BRSK2 | 2.13440180 |
14 | VRK1 | 2.09472107 |
15 | AKT3 | 2.07380014 |
16 | ZAK | 2.05839926 |
17 | TXK | 2.02706722 |
18 | PLK3 | 1.89924927 |
19 | TTK | 1.83849922 |
20 | EIF2AK2 | 1.79217013 |
21 | PLK1 | 1.74340185 |
22 | EIF2AK3 | 1.74255439 |
23 | ATR | 1.67921800 |
24 | STK16 | 1.65692001 |
25 | TLK1 | 1.64856299 |
26 | NEK2 | 1.63136426 |
27 | STK38L | 1.62437696 |
28 | SCYL2 | 1.55660264 |
29 | ACVR1B | 1.54283563 |
30 | VRK2 | 1.53640239 |
31 | MST1R | 1.49589474 |
32 | TAF1 | 1.47583733 |
33 | CDK7 | 1.43453337 |
34 | CHEK2 | 1.42531701 |
35 | SMG1 | 1.41095388 |
36 | CCNB1 | 1.37235073 |
37 | TRIM28 | 1.36361272 |
38 | CLK1 | 1.35507335 |
39 | EEF2K | 1.34941146 |
40 | AURKB | 1.31278974 |
41 | LATS1 | 1.26667730 |
42 | ICK | 1.23645771 |
43 | PASK | 1.23022996 |
44 | MAP3K10 | 1.21843872 |
45 | NEK6 | 1.21191211 |
46 | PNCK | 1.21168926 |
47 | BRSK1 | 1.15713279 |
48 | IRAK4 | 1.13894097 |
49 | MAP3K8 | 1.09574884 |
50 | CDK8 | 1.09022479 |
51 | CHEK1 | 1.06238911 |
52 | MET | 1.05940771 |
53 | ATM | 1.05393995 |
54 | NME2 | 1.04121576 |
55 | PIM1 | 1.03129171 |
56 | STK4 | 1.02345600 |
57 | BRD4 | 1.01678408 |
58 | PAK4 | 1.00871603 |
59 | ALK | 0.99514761 |
60 | TEC | 0.98929492 |
61 | IRAK3 | 0.96716587 |
62 | BMPR2 | 0.95893093 |
63 | STK24 | 0.95001592 |
64 | MAP3K14 | 0.92458831 |
65 | NUAK1 | 0.91280386 |
66 | SGK2 | 0.87345621 |
67 | ERBB4 | 0.87095809 |
68 | AURKA | 0.85678457 |
69 | BCR | 0.83396943 |
70 | BRAF | 0.80982835 |
71 | TGFBR1 | 0.80843731 |
72 | CDK6 | 0.80235735 |
73 | YES1 | 0.79644465 |
74 | ERBB3 | 0.78631152 |
75 | EPHA2 | 0.77948886 |
76 | MST4 | 0.73877064 |
77 | CDK2 | 0.73287572 |
78 | BMPR1B | 0.73225682 |
79 | RPS6KB2 | 0.70948821 |
80 | CDK12 | 0.70445897 |
81 | MAP4K1 | 0.68095047 |
82 | RAF1 | 0.67397865 |
83 | STK10 | 0.66949916 |
84 | * CSNK2A1 | 0.66142642 |
85 | LATS2 | 0.64542502 |
86 | NEK9 | 0.64224927 |
87 | NME1 | 0.64061820 |
88 | CDK1 | 0.62899706 |
89 | FGFR1 | 0.60992007 |
90 | CDK4 | 0.59028724 |
91 | * CSNK2A2 | 0.59005564 |
92 | CSNK1E | 0.58983303 |
93 | KSR1 | 0.58978723 |
94 | STK3 | 0.58755999 |
95 | PLK2 | 0.57873032 |
96 | CDK3 | 0.57482193 |
97 | CHUK | 0.56545053 |
98 | MELK | 0.55018360 |
99 | STK39 | 0.53344367 |
100 | SIK3 | 0.52515567 |
101 | NEK1 | 0.51494368 |
102 | MAP3K2 | 0.50703186 |
103 | RPS6KA4 | 0.49905994 |
104 | RPS6KB1 | 0.48715570 |
105 | BTK | 0.48633275 |
106 | SGK3 | 0.48202164 |
107 | CDK9 | 0.46200723 |
108 | IKBKB | 0.46075039 |
109 | GRK1 | 0.44029837 |
110 | PDK2 | 0.43906693 |
111 | NLK | 0.42887845 |
112 | DYRK3 | 0.42376036 |
113 | IKBKE | 0.41731204 |
114 | PRKDC | 0.40894364 |
115 | JAK3 | 0.39649683 |
116 | TESK1 | 0.39472085 |
117 | MAPK13 | 0.37992874 |
118 | KSR2 | 0.37748193 |
119 | MTOR | 0.36079606 |
120 | PIM2 | 0.36003107 |
121 | RPS6KA6 | 0.35325754 |
122 | TRPM7 | 0.34931086 |
123 | RPS6KA5 | 0.34910482 |
124 | PRPF4B | 0.33939297 |
125 | PRKCI | 0.33079598 |
126 | CDK18 | 0.32540663 |
127 | MAP2K6 | 0.32319081 |
128 | MAPK14 | 0.32260304 |
129 | CAMK1G | 0.32195318 |
130 | MAP3K6 | 0.31076696 |
131 | WNK1 | 0.30818446 |
132 | MAP2K3 | 0.30587948 |
133 | KIT | 0.30518650 |
134 | MINK1 | 0.30278504 |
135 | RPS6KL1 | 0.29828928 |
136 | RPS6KC1 | 0.29828928 |
137 | CSNK1A1L | 0.29188379 |
138 | CDK14 | 0.27670264 |
139 | CDK15 | 0.27409539 |
140 | TNIK | 0.26603729 |
141 | CDK11A | 0.26493036 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.34759536 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.85230893 |
3 | Homologous recombination_Homo sapiens_hsa03440 | 3.56644702 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.50648025 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.32716395 |
6 | Base excision repair_Homo sapiens_hsa03410 | 3.07377476 |
7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.03149794 |
8 | Spliceosome_Homo sapiens_hsa03040 | 2.99609053 |
9 | RNA transport_Homo sapiens_hsa03013 | 2.77581350 |
10 | Cell cycle_Homo sapiens_hsa04110 | 2.75611434 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.72983952 |
12 | Basal transcription factors_Homo sapiens_hsa03022 | 2.63227979 |
13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.58403389 |
14 | Proteasome_Homo sapiens_hsa03050 | 2.52360853 |
15 | Ribosome_Homo sapiens_hsa03010 | 2.49854006 |
16 | RNA degradation_Homo sapiens_hsa03018 | 2.36131600 |
17 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.27523338 |
18 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.19605056 |
19 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.84009286 |
20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.79187288 |
21 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.66501015 |
22 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.54913829 |
23 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.54233644 |
24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.53485512 |
25 | Purine metabolism_Homo sapiens_hsa00230 | 1.49480854 |
26 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.23704581 |
27 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.18672499 |
28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.17487578 |
29 | Carbon metabolism_Homo sapiens_hsa01200 | 1.12471770 |
30 | Protein export_Homo sapiens_hsa03060 | 1.10653461 |
31 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.08357356 |
32 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.05343809 |
33 | * Herpes simplex infection_Homo sapiens_hsa05168 | 1.04409361 |
34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.97490961 |
35 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.93747207 |
36 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.93395067 |
37 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.93194624 |
38 | Measles_Homo sapiens_hsa05162 | 0.90968142 |
39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.89634324 |
40 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.89398241 |
41 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.87069178 |
42 | Thyroid cancer_Homo sapiens_hsa05216 | 0.86144284 |
43 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.83941817 |
44 | Lysine degradation_Homo sapiens_hsa00310 | 0.81549501 |
45 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.80975055 |
46 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.80427049 |
47 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.80318897 |
48 | Adherens junction_Homo sapiens_hsa04520 | 0.78930712 |
49 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.78744179 |
50 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.76569133 |
51 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.76535480 |
52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.76299979 |
53 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.75589504 |
54 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.74916841 |
55 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.74318057 |
56 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.72906290 |
57 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.72396825 |
58 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.71861360 |
59 | HTLV-I infection_Homo sapiens_hsa05166 | 0.71531903 |
60 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.70009198 |
61 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.68256940 |
62 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.68067799 |
63 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.67966888 |
64 | Allograft rejection_Homo sapiens_hsa05330 | 0.67449138 |
65 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.64058018 |
66 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.58888001 |
67 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.58853203 |
68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.56126747 |
69 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.55811846 |
70 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.55368654 |
71 | Huntingtons disease_Homo sapiens_hsa05016 | 0.54679353 |
72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.51310662 |
73 | Influenza A_Homo sapiens_hsa05164 | 0.50603665 |
74 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.49572827 |
75 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.49291703 |
76 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.49066600 |
77 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.48852608 |
78 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.48257868 |
79 | Phototransduction_Homo sapiens_hsa04744 | 0.46666482 |
80 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.46471296 |
81 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.46241225 |
82 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.44540220 |
83 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.43348643 |
84 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.42347578 |
85 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.41139062 |
86 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.40952831 |
87 | Bladder cancer_Homo sapiens_hsa05219 | 0.40416666 |
88 | Sulfur relay system_Homo sapiens_hsa04122 | 0.39773193 |
89 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.39703108 |
90 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.39011695 |
91 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.38004509 |
92 | Prostate cancer_Homo sapiens_hsa05215 | 0.37829384 |
93 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.37775409 |
94 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.37166041 |
95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.37057949 |
96 | Endometrial cancer_Homo sapiens_hsa05213 | 0.36936189 |
97 | Legionellosis_Homo sapiens_hsa05134 | 0.36425753 |
98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35875490 |
99 | Asthma_Homo sapiens_hsa05310 | 0.35670096 |
100 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.35077004 |
101 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.34713636 |
102 | Hepatitis B_Homo sapiens_hsa05161 | 0.34437817 |
103 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.34274094 |
104 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.32246509 |
105 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.31763003 |
106 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.31038150 |
107 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.30464647 |
108 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.30240832 |
109 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.30054595 |
110 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.29190879 |
111 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.28919978 |
112 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.26889331 |
113 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.26427354 |
114 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.25405494 |
115 | Pathways in cancer_Homo sapiens_hsa05200 | 0.24562380 |
116 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.24066195 |
117 | Apoptosis_Homo sapiens_hsa04210 | 0.22824229 |
118 | Colorectal cancer_Homo sapiens_hsa05210 | 0.22637453 |
119 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.22586569 |
120 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.22467200 |
121 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.22362632 |
122 | Alcoholism_Homo sapiens_hsa05034 | 0.22052715 |
123 | Melanoma_Homo sapiens_hsa05218 | 0.21724264 |
124 | Glioma_Homo sapiens_hsa05214 | 0.21462015 |
125 | Parkinsons disease_Homo sapiens_hsa05012 | 0.20871623 |
126 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.19940815 |
127 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.19766860 |
128 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.19063431 |
129 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.18892608 |
130 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.18718371 |
131 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.17922985 |
132 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.16892361 |
133 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.15583062 |
134 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.15078702 |
135 | Circadian rhythm_Homo sapiens_hsa04710 | 0.14516446 |
136 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.14474387 |
137 | Leishmaniasis_Homo sapiens_hsa05140 | 0.14281695 |
138 | Metabolic pathways_Homo sapiens_hsa01100 | 0.13815636 |
139 | Shigellosis_Homo sapiens_hsa05131 | 0.12493915 |
140 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.10727958 |
141 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.10643413 |