SRRM2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)4.89297171
2negative regulation of erythrocyte differentiation (GO:0045647)4.81785983
3histone H3-K4 trimethylation (GO:0080182)4.53346435
4regulation of histone H3-K27 methylation (GO:0061085)4.46142402
5cytoplasmic mRNA processing body assembly (GO:0033962)4.13838683
6histone H3-K4 methylation (GO:0051568)3.98160601
7mannose metabolic process (GO:0006013)3.85215628
8mitotic sister chromatid cohesion (GO:0007064)3.80664900
9glucocorticoid receptor signaling pathway (GO:0042921)3.70403545
10peptidyl-lysine dimethylation (GO:0018027)3.55710280
11NLS-bearing protein import into nucleus (GO:0006607)3.48457424
12stress granule assembly (GO:0034063)3.47380655
13positive regulation of histone deacetylation (GO:0031065)3.39623092
14positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.36637885
15sodium ion export (GO:0071436)3.34694903
16peptidyl-lysine trimethylation (GO:0018023)3.33728824
17nuclear pore complex assembly (GO:0051292)3.30682316
18histone lysine methylation (GO:0034968)3.29179468
19negative regulation of myotube differentiation (GO:0010832)3.26569947
20negative regulation of histone methylation (GO:0031061)3.23764179
21cerebellar Purkinje cell differentiation (GO:0021702)3.23688012
22positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.22914167
23cytoskeletal anchoring at plasma membrane (GO:0007016)3.20031199
24locomotory exploration behavior (GO:0035641)3.18351613
25histone demethylation (GO:0016577)3.18348220
26regulation of RNA export from nucleus (GO:0046831)3.17472075
27positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)3.17350597
28negative regulation of translation, ncRNA-mediated (GO:0040033)3.13103726
29regulation of translation, ncRNA-mediated (GO:0045974)3.13103726
30negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.13103726
31negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.12785562
32negative regulation of cell killing (GO:0031342)3.12785562
33corticosteroid receptor signaling pathway (GO:0031958)3.11494142
34cell-substrate adherens junction assembly (GO:0007045)3.11021411
35focal adhesion assembly (GO:0048041)3.11021411
36regulation of NFAT protein import into nucleus (GO:0051532)3.08102358
37response to muramyl dipeptide (GO:0032495)3.05274387
38regulation of ARF protein signal transduction (GO:0032012)3.03383966
39histone H4-K16 acetylation (GO:0043984)2.99109024
40establishment of nucleus localization (GO:0040023)2.98460198
41positive regulation of gene expression, epigenetic (GO:0045815)2.97873938
42embryonic process involved in female pregnancy (GO:0060136)2.96774431
43peptidyl-lysine methylation (GO:0018022)2.95829209
443-UTR-mediated mRNA stabilization (GO:0070935)2.95793793
45synaptic vesicle maturation (GO:0016188)2.93558067
46response to laminar fluid shear stress (GO:0034616)2.92219195
47regulation of nucleobase-containing compound transport (GO:0032239)2.92137117
48regulation of clathrin-mediated endocytosis (GO:2000369)2.91866397
49positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.86169594
50insulin-like growth factor receptor signaling pathway (GO:0048009)2.84595462
51histone H3-K9 demethylation (GO:0033169)2.81713014
52cellular response to epidermal growth factor stimulus (GO:0071364)2.78738138
53nuclear pore organization (GO:0006999)2.78201398
54regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.78058690
55histone H3-K36 demethylation (GO:0070544)2.74122477
56histone methylation (GO:0016571)2.72697700
57protein demethylation (GO:0006482)2.72167200
58protein dealkylation (GO:0008214)2.72167200
59positive regulation of RNA splicing (GO:0033120)2.70309883
60regulation of gamma-delta T cell differentiation (GO:0045586)2.69567186
61layer formation in cerebral cortex (GO:0021819)2.69051305
62response to epidermal growth factor (GO:0070849)2.68073089
63regulation of short-term neuronal synaptic plasticity (GO:0048172)2.66888420
64planar cell polarity pathway involved in neural tube closure (GO:0090179)2.66824434
65histone H4 deacetylation (GO:0070933)2.66752883
66activation of Rac GTPase activity (GO:0032863)2.62099465
67retrograde transport, vesicle recycling within Golgi (GO:0000301)2.60317113
68positive thymic T cell selection (GO:0045059)2.59384416
69intracellular estrogen receptor signaling pathway (GO:0030520)2.59383201
70cellular potassium ion homeostasis (GO:0030007)2.58070407
71negative thymic T cell selection (GO:0045060)2.58062515
72semaphorin-plexin signaling pathway (GO:0071526)2.57345943
73positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.56973418
74apoptotic process involved in morphogenesis (GO:0060561)2.56849066
75peptidyl-threonine phosphorylation (GO:0018107)2.54431749
76negative regulation of fatty acid transport (GO:2000192)2.53680466
77thymic T cell selection (GO:0045061)2.52565863
78regulation of glucose import in response to insulin stimulus (GO:2001273)2.52221455
79negative T cell selection (GO:0043383)2.51337094
80positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.50682081
81regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.50682081
82regulation of ARF GTPase activity (GO:0032312)2.50641398
83epithelial cell differentiation involved in prostate gland development (GO:0060742)2.49950047
84negative regulation of cell size (GO:0045792)2.49671040
85cell-substrate junction assembly (GO:0007044)2.49106675
86positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.48866380
87positive regulation of CREB transcription factor activity (GO:0032793)2.47733894
88mRNA stabilization (GO:0048255)2.46208040
89RNA stabilization (GO:0043489)2.46208040
90embryonic camera-type eye morphogenesis (GO:0048596)2.46090338
91dosage compensation (GO:0007549)2.45694255
92histone H4 acetylation (GO:0043967)2.44985761
93establishment of protein localization to Golgi (GO:0072600)2.43386019
94chromatin silencing (GO:0006342)2.43305902
95positive regulation of gamma-delta T cell activation (GO:0046645)2.43019769
96histone deubiquitination (GO:0016578)2.41484433
97peptidyl-threonine modification (GO:0018210)2.41355645
98positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.41089549
99regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.41089549
100regulation of chromatin binding (GO:0035561)2.38883136
101antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.37295775
102protein targeting to Golgi (GO:0000042)2.36233241
103heterochromatin organization (GO:0070828)2.35512511
104spliceosomal tri-snRNP complex assembly (GO:0000244)2.35375393
105positive regulation of protein deacetylation (GO:0090312)2.35135483
106histone H3 deacetylation (GO:0070932)2.34850457
107embryonic eye morphogenesis (GO:0048048)2.34796411
108synaptic vesicle docking involved in exocytosis (GO:0016081)2.34476331
109negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.34287521
110modulation by virus of host process (GO:0019054)2.34280643
111positive regulation by host of viral transcription (GO:0043923)2.34057683
112histone H4-K8 acetylation (GO:0043982)2.32841680
113histone H4-K5 acetylation (GO:0043981)2.32841680
114heart morphogenesis (GO:0003007)2.32602654
115positive T cell selection (GO:0043368)2.32232946
116cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.31608965
117regulation of gamma-delta T cell activation (GO:0046643)2.31585017
118gene silencing (GO:0016458)2.31565183
119regulation of histone methylation (GO:0031060)2.31175596
120mRNA splice site selection (GO:0006376)2.30744313
121histone H3-K9 methylation (GO:0051567)2.29085971
122histone lysine demethylation (GO:0070076)2.28991482
123T cell selection (GO:0045058)2.28418465
124regulation of histone H3-K4 methylation (GO:0051569)2.28128352
125antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.27833692
126regulation of extracellular matrix disassembly (GO:0010715)2.27141311
127trophectodermal cell differentiation (GO:0001829)2.26454755
128pore complex assembly (GO:0046931)2.26224628
129regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.26137786
130nucleus localization (GO:0051647)2.25898501
131cellular response to virus (GO:0098586)2.25620561
132adherens junction assembly (GO:0034333)2.24076391
133modulation by symbiont of host cellular process (GO:0044068)2.23575024
134histone H3-K9 modification (GO:0061647)2.23237682
135positive regulation of Rap GTPase activity (GO:0032854)2.23052407
136regulation of histone deacetylation (GO:0031063)2.22864726
137mucosal-associated lymphoid tissue development (GO:0048537)2.22021867
138Peyers patch development (GO:0048541)2.22021867
139activation of JUN kinase activity (GO:0007257)2.20176715
140negative regulation of histone modification (GO:0031057)2.20114629
141negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.18441038
142regulation of mRNA catabolic process (GO:0061013)2.17800890
143positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.17140989
144positive regulation of mRNA catabolic process (GO:0061014)2.16351032
145protein-DNA complex disassembly (GO:0032986)2.15939515
146nucleosome disassembly (GO:0006337)2.15939515
147cell communication by electrical coupling (GO:0010644)2.15488818
148negative regulation of gene expression, epigenetic (GO:0045814)2.15279534
149regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.12187351

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.65085460
2EGR1_19374776_ChIP-ChIP_THP-1_Human3.46402221
3MYC_22102868_ChIP-Seq_BL_Human3.26459545
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.97780004
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.93164617
6FOXM1_23109430_ChIP-Seq_U2OS_Human2.62494585
7E2F7_22180533_ChIP-Seq_HELA_Human2.61253360
8KDM2B_26808549_Chip-Seq_DND41_Human2.61182575
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.56979304
10KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.48898339
11TCF7_22412390_ChIP-Seq_EML_Mouse2.46888225
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.46412977
13KDM2B_26808549_Chip-Seq_SUP-B15_Human2.38555039
14DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.33216372
15KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.26684903
16DROSHA_22980978_ChIP-Seq_HELA_Human2.20524108
17ZFP281_27345836_Chip-Seq_ESCs_Mouse2.19914153
18KDM2B_26808549_Chip-Seq_JURKAT_Human2.10499911
19FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.08871670
20KDM2B_26808549_Chip-Seq_K562_Human1.99472660
21TP63_17297297_ChIP-ChIP_HaCaT_Human1.98786366
22WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.97753007
23TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.94767702
24SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.94620499
25TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.92202724
26* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.89507285
27VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.88313942
28SALL1_21062744_ChIP-ChIP_HESCs_Human1.86030333
29RARB_27405468_Chip-Seq_BRAIN_Mouse1.80878205
30* VDR_21846776_ChIP-Seq_THP-1_Human1.72767708
31TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.67822338
32NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.61889573
33EZH2_22144423_ChIP-Seq_EOC_Human1.57140442
34PKCTHETA_26484144_Chip-Seq_BREAST_Human1.55850581
35MAF_26560356_Chip-Seq_TH2_Human1.54886654
36FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.54837658
37EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.54610245
38RARG_19884340_ChIP-ChIP_MEFs_Mouse1.52662211
39FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.52485848
40* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.50779273
41KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.49886923
42RUNX_20019798_ChIP-Seq_JUKART_Human1.49024463
43* UTX_26944678_Chip-Seq_JUKART_Human1.47433702
44GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.46585983
45P300_27058665_Chip-Seq_ZR-75-30cells_Human1.45324928
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.44328753
47SMC4_20622854_ChIP-Seq_HELA_Human1.43945765
48MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.38459086
49CLOCK_20551151_ChIP-Seq_293T_Human1.38436264
50SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.37803558
51CTCF_27219007_Chip-Seq_ERYTHROID_Human1.36116639
52MAF_26560356_Chip-Seq_TH1_Human1.35273311
53BRD4_27068464_Chip-Seq_AML-cells_Mouse1.35265004
54CTNNB1_20460455_ChIP-Seq_HCT116_Human1.33449803
55ISL1_27105846_Chip-Seq_CPCs_Mouse1.32794158
56KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.31577739
57SPI1_23127762_ChIP-Seq_K562_Human1.31214596
58ELK3_25401928_ChIP-Seq_HUVEC_Human1.30463337
59NFIB_24661679_ChIP-Seq_LUNG_Mouse1.29827619
60GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.29691419
61* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.28568592
62* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.27736818
63* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.27015997
64E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.26264666
65* CIITA_25753668_ChIP-Seq_RAJI_Human1.26244443
66NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.26182948
67CREB1_26743006_Chip-Seq_LNCaP_Human1.26083061
68SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.25850787
69SA1_27219007_Chip-Seq_ERYTHROID_Human1.24150045
70* P68_20966046_ChIP-Seq_HELA_Human1.23614543
71TP53_16413492_ChIP-PET_HCT116_Human1.21294078
72* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.20694407
73UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.20676396
74STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.19441129
75* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.16665887
76ZNF217_24962896_ChIP-Seq_MCF-7_Human1.16401879
77RUNX1_27514584_Chip-Seq_MCF-7_Human1.15479633
78MYB_21317192_ChIP-Seq_ERMYB_Mouse1.14717203
79* LXR_22292898_ChIP-Seq_THP-1_Human1.12713146
80CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.11285736
81FOXA2_19822575_ChIP-Seq_HepG2_Human1.10941946
82IKZF1_21737484_ChIP-ChIP_HCT116_Human1.10325059
83SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08799164
84* AR_19668381_ChIP-Seq_PC3_Human1.08159452
85ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.08021368
86GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07864624
87KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.07368351
88NCOR1_26117541_ChIP-Seq_K562_Human1.05922439
89* TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.05080062
90ERG_21242973_ChIP-ChIP_JURKAT_Human1.03892330
91MYB_26560356_Chip-Seq_TH1_Human1.03855164
92SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03661555
93TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03395805
94AHR_22903824_ChIP-Seq_MCF-7_Human1.03319556
95DNAJC2_21179169_ChIP-ChIP_NT2_Human1.03260850
96ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.02536246
97STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.02408729
98MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.01930204
99* VDR_24763502_ChIP-Seq_THP-1_Human1.00471396
100RACK7_27058665_Chip-Seq_MCF-7_Human0.99508646
101ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.99422694
102FOXO3_23340844_ChIP-Seq_DLD1_Human0.97340422
103TP63_19390658_ChIP-ChIP_HaCaT_Human0.97290080
104SMAD_19615063_ChIP-ChIP_OVARY_Human0.96944027
105* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.96385383
106NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.95624807
107TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.95445904
108HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95201194
109GATA1_19941826_ChIP-Seq_K562_Human0.95170915
110TBX3_20139965_ChIP-Seq_ESCs_Mouse0.94254403
111ESR2_21235772_ChIP-Seq_MCF-7_Human0.93980162
112ZNF263_19887448_ChIP-Seq_K562_Human0.93904847
113SCL_19346495_ChIP-Seq_HPC-7_Human0.93242490
114TBX3_20139965_ChIP-Seq_MESCs_Mouse0.93115386
115FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.92341084
116* TBX20_22080862_ChIP-Seq_HEART_Mouse0.92092501
117* TBX20_22328084_ChIP-Seq_HEART_Mouse0.92092501
118TET1_21451524_ChIP-Seq_MESCs_Mouse0.91787204
119CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.90977389
120SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.89838723
121TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.89213086
122* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.89011449
123NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.88151083
124ARNT_22903824_ChIP-Seq_MCF-7_Human0.88111429
125TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87890532
126* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87269137
127IRF8_22096565_ChIP-ChIP_GC-B_Human0.87202419
128TP53_22127205_ChIP-Seq_IMR90_Human0.87044999
129THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.86163139
130* MYB_26560356_Chip-Seq_TH2_Human0.85320621
131SOX9_24532713_ChIP-Seq_HFSC_Mouse0.85102118
132GATA1_19941827_ChIP-Seq_MEL_Mouse0.84970052
133TCF4_18268006_ChIP-ChIP_LS174T_Human0.84739753
134ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.82173736

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation5.06843929
2MP0005076_abnormal_cell_differentiation3.34822639
3MP0004859_abnormal_synaptic_plasticity3.13589298
4MP0008961_abnormal_basal_metabolism2.93597196
5MP0003787_abnormal_imprinting2.86488614
6MP0003300_gastrointestinal_ulcer2.82844941
7MP0005409_darkened_coat_color2.67905532
8MP0002009_preneoplasia2.58084136
9MP0005451_abnormal_body_composition2.45795026
10MP0003705_abnormal_hypodermis_morpholog2.38781210
11MP0010352_gastrointestinal_tract_polyps2.33057201
12MP0003045_fibrosis2.14569241
13MP0003436_decreased_susceptibility_to2.04116957
14MP0009278_abnormal_bone_marrow1.93463940
15MP0010234_abnormal_vibrissa_follicle1.92330661
16MP0001348_abnormal_lacrimal_gland1.89489707
17MP0003121_genomic_imprinting1.89100679
18MP0002249_abnormal_larynx_morphology1.77027072
19MP0000733_abnormal_muscle_development1.76559056
20MP0004808_abnormal_hematopoietic_stem1.73011264
21MP0008260_abnormal_autophagy1.72236933
22MP0009780_abnormal_chondrocyte_physiolo1.71144896
23MP0005666_abnormal_adipose_tissue1.69584280
24MP0003283_abnormal_digestive_organ1.63287072
25MP0004947_skin_inflammation1.62532835
26MP0010307_abnormal_tumor_latency1.52469909
27MP0002396_abnormal_hematopoietic_system1.50149511
28MP0003303_peritoneal_inflammation1.49514153
29MP0005187_abnormal_penis_morphology1.48375376
30MP0003122_maternal_imprinting1.48216382
31MP0008877_abnormal_DNA_methylation1.47374713
32MP0004381_abnormal_hair_follicle1.45717947
33MP0002166_altered_tumor_susceptibility1.45696675
34MP0004197_abnormal_fetal_growth/weight/1.42480382
35MP0004233_abnormal_muscle_weight1.40529773
36MP0003453_abnormal_keratinocyte_physiol1.40166998
37MP0008569_lethality_at_weaning1.38682834
38MP0001849_ear_inflammation1.36911990
39MP0002084_abnormal_developmental_patter1.36748765
40MP0005058_abnormal_lysosome_morphology1.35218365
41MP0003635_abnormal_synaptic_transmissio1.34391554
42MP0009703_decreased_birth_body1.33421871
43MP0003123_paternal_imprinting1.30506845
44MP0000678_abnormal_parathyroid_gland1.29004549
45MP0003115_abnormal_respiratory_system1.28893878
46MP0003890_abnormal_embryonic-extraembry1.27997077
47MP0002909_abnormal_adrenal_gland1.26632632
48MP0000428_abnormal_craniofacial_morphol1.25037064
49MP0000703_abnormal_thymus_morphology1.24819902
50MP0000003_abnormal_adipose_tissue1.24581204
51MP0009672_abnormal_birth_weight1.22100547
52MP0004264_abnormal_extraembryonic_tissu1.20252596
53MP0001800_abnormal_humoral_immune1.19662795
54MP0003984_embryonic_growth_retardation1.19008736
55MP0002088_abnormal_embryonic_growth/wei1.18355719
56MP0002925_abnormal_cardiovascular_devel1.17941157
57MP0004510_myositis1.17094278
58MP0003091_abnormal_cell_migration1.16992529
59MP0003763_abnormal_thymus_physiology1.14504529
60MP0001299_abnormal_eye_distance/1.14229381
61MP0003935_abnormal_craniofacial_develop1.13970706
62MP0002086_abnormal_extraembryonic_tissu1.13861434
63MP0004885_abnormal_endolymph1.12925678
64MP0001672_abnormal_embryogenesis/_devel1.12452089
65MP0005380_embryogenesis_phenotype1.12452089
66MP0002089_abnormal_postnatal_growth/wei1.09899179
67MP0001851_eye_inflammation1.08198536
68MP0003566_abnormal_cell_adhesion1.08149838
69MP0000685_abnormal_immune_system1.07772282
70MP0000537_abnormal_urethra_morphology1.07611124
71MP0000350_abnormal_cell_proliferation1.05759548
72MP0002998_abnormal_bone_remodeling1.05469974
73MP0002653_abnormal_ependyma_morphology1.04314021
74MP0002085_abnormal_embryonic_tissue1.03673760
75MP0001730_embryonic_growth_arrest1.02794289
76MP0001835_abnormal_antigen_presentation1.02324144
77MP0003866_abnormal_defecation1.02045514
78MP0009046_muscle_twitch1.01592828
79MP0010630_abnormal_cardiac_muscle1.00479003
80MP0003690_abnormal_glial_cell0.99390518
81MP0005623_abnormal_meninges_morphology0.99293287
82MP0004185_abnormal_adipocyte_glucose0.98773921
83MP0002722_abnormal_immune_system0.98529705
84MP0000858_altered_metastatic_potential0.97127834
85MP0002405_respiratory_system_inflammati0.96807896
86MP0003172_abnormal_lysosome_physiology0.96336091
87MP0000716_abnormal_immune_system0.96187844
88MP0002006_tumorigenesis0.95902759
89MP0009115_abnormal_fat_cell0.95863809
90MP0001873_stomach_inflammation0.95509204
91MP0006138_congestive_heart_failure0.95236188
92MP0009333_abnormal_splenocyte_physiolog0.95145740
93MP0003828_pulmonary_edema0.94807069
94MP0005387_immune_system_phenotype0.94785889
95MP0001790_abnormal_immune_system0.94785889
96MP0004858_abnormal_nervous_system0.94512683
97MP0008770_decreased_survivor_rate0.93347030
98MP0003861_abnormal_nervous_system0.93082177
99MP0003111_abnormal_nucleus_morphology0.92395503
100MP0005375_adipose_tissue_phenotype0.92325334
101MP0002796_impaired_skin_barrier0.92033641
102MP0002420_abnormal_adaptive_immunity0.91692789
103MP0001958_emphysema0.91199184
104MP0000566_synostosis0.90592970
105MP0001819_abnormal_immune_cell0.90383438
106MP0004811_abnormal_neuron_physiology0.89678106
107MP0003279_aneurysm0.89124153
108MP0005670_abnormal_white_adipose0.88532233
109MP0000266_abnormal_heart_morphology0.88405243
110MP0001697_abnormal_embryo_size0.87966925
111MP0004130_abnormal_muscle_cell0.87488850
112MP0002429_abnormal_blood_cell0.86550930
113MP0005025_abnormal_response_to0.86487736
114MP0001784_abnormal_fluid_regulation0.86361531
115MP0010155_abnormal_intestine_physiology0.86103950
116MP0002970_abnormal_white_adipose0.85516870
117MP0008057_abnormal_DNA_replication0.85465398
118MP0005000_abnormal_immune_tolerance0.85139856
119MP0000534_abnormal_ureter_morphology0.83176467
120MP0002419_abnormal_innate_immunity0.82247104
121MP0002723_abnormal_immune_serum0.81845366
122MP0005423_abnormal_somatic_nervous0.81156091
123MP0009931_abnormal_skin_appearance0.80238713
124MP0002928_abnormal_bile_duct0.79807212
125MP0000759_abnormal_skeletal_muscle0.79802496
126MP0002452_abnormal_antigen_presenting0.78723892
127MP0002152_abnormal_brain_morphology0.78505057
128MP0000767_abnormal_smooth_muscle0.78220421
129MP0002063_abnormal_learning/memory/cond0.78045499
130MP0002877_abnormal_melanocyte_morpholog0.77681732
131MP0002933_joint_inflammation0.77626014
132MP0003385_abnormal_body_wall0.77129833
133MP0002080_prenatal_lethality0.77015777
134MP0002398_abnormal_bone_marrow0.74770515
135MP0003119_abnormal_digestive_system0.74217198
136MP0000432_abnormal_head_morphology0.74081556
137MP0010678_abnormal_skin_adnexa0.72040867
138MP0005621_abnormal_cell_physiology0.70890966
139MP0004087_abnormal_muscle_fiber0.69795312
140MP0002697_abnormal_eye_size0.69106363
141MP0005397_hematopoietic_system_phenotyp0.66993240
142MP0001545_abnormal_hematopoietic_system0.66993240
143MP0000371_diluted_coat_color0.66236697
144MP0002234_abnormal_pharynx_morphology0.65588890
145MP0001915_intracranial_hemorrhage0.65538368
146MP0002168_other_aberrant_phenotype0.65508348
147MP0004145_abnormal_muscle_electrophysio0.65261860
148MP0004270_analgesia0.64947235
149MP0009053_abnormal_anal_canal0.64824140

Predicted human phenotypes

RankGene SetZ-score
1Obstructive sleep apnea (HP:0002870)4.22838384
2Abnormality of the fingertips (HP:0001211)4.11805727
3Macroorchidism (HP:0000053)3.78295754
4Broad face (HP:0000283)3.51785450
5Hyperacusis (HP:0010780)3.45975721
6Short 4th metacarpal (HP:0010044)3.16236168
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.16236168
8Urethral obstruction (HP:0000796)3.04406480
9Narrow palate (HP:0000189)2.95872665
10Long eyelashes (HP:0000527)2.95865697
11Volvulus (HP:0002580)2.86893844
12Trigonocephaly (HP:0000243)2.79581933
13Elfin facies (HP:0004428)2.77640726
14Cerebral aneurysm (HP:0004944)2.71670863
15Heterotopia (HP:0002282)2.66482149
16Obsessive-compulsive behavior (HP:0000722)2.61321272
17Genetic anticipation (HP:0003743)2.55238042
18Renovascular hypertension (HP:0100817)2.52383681
19Dysmetric saccades (HP:0000641)2.51570118
20Shallow orbits (HP:0000586)2.51070007
21Pointed chin (HP:0000307)2.49395443
22Flat acetabular roof (HP:0003180)2.43822540
23Increased nuchal translucency (HP:0010880)2.43729606
24Abnormality of the radial head (HP:0003995)2.39313460
25Abnormality of the distal phalanx of the thumb (HP:0009617)2.37785612
26Anal stenosis (HP:0002025)2.36212944
27Abnormality of the 4th metacarpal (HP:0010012)2.34666312
28Abnormality of the astrocytes (HP:0100707)2.31842396
29Astrocytoma (HP:0009592)2.31842396
30Colitis (HP:0002583)2.30876261
31Renal duplication (HP:0000075)2.29002287
32Neoplasm of the heart (HP:0100544)2.27542769
33Eczematoid dermatitis (HP:0000976)2.26970824
34Insomnia (HP:0100785)2.25339049
35Metaphyseal cupping (HP:0003021)2.19081808
36Overriding aorta (HP:0002623)2.14760385
37Broad thumb (HP:0011304)2.13888984
38Absent frontal sinuses (HP:0002688)2.13840177
39Vertebral arch anomaly (HP:0008438)2.13667069
40Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.13117627
41Ependymoma (HP:0002888)2.12331015
42Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.10910122
43Hemiplegia (HP:0002301)2.10400325
44Abnormality of the columella (HP:0009929)2.09955879
45Truncal obesity (HP:0001956)2.07056059
46Persistence of primary teeth (HP:0006335)2.06577159
47Bronchomalacia (HP:0002780)2.05632212
48Aortic aneurysm (HP:0004942)2.05370197
49Prominent nose (HP:0000448)2.04500359
50Distal lower limb amyotrophy (HP:0008944)2.02205834
51Sparse lateral eyebrow (HP:0005338)2.01420878
52Bowel diverticulosis (HP:0005222)1.99178041
53Broad palm (HP:0001169)1.98970674
54Ulnar bowing (HP:0003031)1.98108841
55Centrally nucleated skeletal muscle fibers (HP:0003687)1.97822744
56Abnormality of the lower motor neuron (HP:0002366)1.97437396
57Thin bony cortex (HP:0002753)1.97184510
58Pseudobulbar signs (HP:0002200)1.97144225
59Increased IgE level (HP:0003212)1.96272303
60Sacral dimple (HP:0000960)1.94217860
61Impaired smooth pursuit (HP:0007772)1.93665317
62Germ cell neoplasia (HP:0100728)1.92795476
63Supernumerary ribs (HP:0005815)1.92775154
64Aqueductal stenosis (HP:0002410)1.92637694
65Action tremor (HP:0002345)1.90913482
66Cellulitis (HP:0100658)1.90251698
67Segmental peripheral demyelination/remyelination (HP:0003481)1.90138952
68Enlarged penis (HP:0000040)1.89073241
69Abnormality of the thoracic spine (HP:0100711)1.88539470
70Skin tags (HP:0010609)1.86684014
71Neonatal hypoglycemia (HP:0001998)1.86339964
72Thick eyebrow (HP:0000574)1.85802268
73Protrusio acetabuli (HP:0003179)1.84230935
74Glioma (HP:0009733)1.82773259
75Abnormality of ocular smooth pursuit (HP:0000617)1.82192839
76Neoplasm of the oral cavity (HP:0100649)1.80551368
77Increased connective tissue (HP:0009025)1.80048582
78Aneurysm (HP:0002617)1.79615030
79Abnormality of the nasal septum (HP:0000419)1.79172137
80Slow saccadic eye movements (HP:0000514)1.79084853
81Flat cornea (HP:0007720)1.78287852
82Smooth philtrum (HP:0000319)1.78280736
83Gastrointestinal inflammation (HP:0004386)1.77975655
84Syringomyelia (HP:0003396)1.77935091
85Spinal cord lesions (HP:0100561)1.77935091
86Asymmetry of the thorax (HP:0001555)1.76957436
87Deep palmar crease (HP:0006191)1.76665552
88Increased density of long bones (HP:0006392)1.75607085
89Upper limb amyotrophy (HP:0009129)1.74691458
90Distal upper limb amyotrophy (HP:0007149)1.74691458
91Broad metatarsal (HP:0001783)1.74192123
92Broad phalanges of the hand (HP:0009768)1.73988984
93Urinary bladder sphincter dysfunction (HP:0002839)1.73736021
94Abnormality of the diencephalon (HP:0010662)1.73390899
95Abnormality of the humeroradial joint (HP:0100744)1.72225313
96Precocious puberty (HP:0000826)1.71682195
97Hemorrhage of the eye (HP:0011885)1.71595045
98Lip pit (HP:0100267)1.71401584
99Hand muscle atrophy (HP:0009130)1.71304706
100Limited elbow extension (HP:0001377)1.71138238
101Bowel incontinence (HP:0002607)1.70536102
102Attention deficit hyperactivity disorder (HP:0007018)1.70280559
103Onion bulb formation (HP:0003383)1.69975810
104Mitral valve prolapse (HP:0001634)1.69879761
105Thin ribs (HP:0000883)1.69540137
106Abnormality of the epiphyses of the hand (HP:0005924)1.68565199
107Ankyloglossia (HP:0010296)1.67770134
108Depressed nasal tip (HP:0000437)1.67088794
109Abnormality of oral frenula (HP:0000190)1.66977732
110Focal seizures (HP:0007359)1.66923835
111Annular pancreas (HP:0001734)1.66711112
112Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.65710140
113Long palpebral fissure (HP:0000637)1.65708314
114Mitral regurgitation (HP:0001653)1.64646996
115Broad finger (HP:0001500)1.64243141
116Sandal gap (HP:0001852)1.64078501
117Advanced eruption of teeth (HP:0006288)1.63676765
118Transitional cell carcinoma of the bladder (HP:0006740)1.63345297
119Deviation of the thumb (HP:0009603)1.62522548
120Ureteral stenosis (HP:0000071)1.62278052
121Proximal placement of thumb (HP:0009623)1.62170884
122Low anterior hairline (HP:0000294)1.62076102
123Gastrointestinal carcinoma (HP:0002672)1.61678349
124Malignant gastrointestinal tract tumors (HP:0006749)1.61678349
125Subacute progressive viral hepatitis (HP:0006572)1.60607154
126Turricephaly (HP:0000262)1.59572309
127Cutis marmorata (HP:0000965)1.58841113
128Thoracic kyphosis (HP:0002942)1.58101051
129Gingivitis (HP:0000230)1.57880147
130Disproportionate tall stature (HP:0001519)1.56413631
131Leiomyosarcoma (HP:0100243)1.55941586
132Uterine leiomyosarcoma (HP:0002891)1.55941586
133Abnormality of the aortic arch (HP:0012303)1.55935614
134Hypoplasia of the maxilla (HP:0000327)1.55906053
135Lower limb amyotrophy (HP:0007210)1.55860394
136Oligodontia (HP:0000677)1.55326815
137Increased variability in muscle fiber diameter (HP:0003557)1.55126059
138Patellar dislocation (HP:0002999)1.54257665
139Dislocated radial head (HP:0003083)1.53560318
140Supernumerary bones of the axial skeleton (HP:0009144)1.53226628
141Viral hepatitis (HP:0006562)1.52837831
142Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.52738487
143Emphysema (HP:0002097)1.52462690
144Midline defect of the nose (HP:0004122)1.52302349
145Ureteral obstruction (HP:0006000)1.52258954
146Inflammation of the large intestine (HP:0002037)1.52055077
147Cervical subluxation (HP:0003308)1.52032297
148Premature skin wrinkling (HP:0100678)1.51822716
149Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.51435229
150Deep venous thrombosis (HP:0002625)1.51422418
151Abnormality of the calcaneus (HP:0008364)1.51400743
152Skull defect (HP:0001362)1.50958700
153Biconcave vertebral bodies (HP:0004586)1.50594336
154Broad phalanx (HP:0006009)1.49550320
155Abnormal large intestine physiology (HP:0012700)1.48800872
156Supernumerary nipples (HP:0002558)1.46829872
157Abnormality of the phalanges of the hallux (HP:0010057)1.46118838
158Arnold-Chiari malformation (HP:0002308)1.45944130
159Recurrent viral infections (HP:0004429)1.45895074
160Dilatation of the ascending aorta (HP:0005111)1.43712448
161Seborrheic dermatitis (HP:0001051)1.42198309
162Joint laxity (HP:0001388)1.41352913

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.80745844
2PRPF4B3.33469622
3CAMK1G3.27092676
4CAMK1D2.81913217
5BRD42.75335977
6SMG12.69691688
7EEF2K2.62961966
8SIK22.39964421
9MAP3K102.39563813
10RIPK12.31934952
11TRIB32.24540094
12RIPK41.80845553
13PKN21.80257111
14SIK11.73674734
15ALK1.67484806
16ICK1.65849170
17TAOK11.57938217
18MAP4K11.56284880
19MAP3K91.53500834
20MAP3K71.52637228
21PTK61.49755921
22LATS11.49718198
23* MTOR1.41236870
24PDGFRA1.41160995
25PNCK1.35867801
26TYRO31.31876230
27FGFR31.31218978
28PRKD31.29154129
29DMPK1.28874027
30WNK11.26941867
31NTRK31.26680722
32TTN1.25301367
33STK381.25198236
34SGK31.24450867
35PRKCH1.19949092
36NEK21.17810543
37CDK61.16249485
38TNK21.12112593
39PDGFRB1.09429675
40FGFR21.08792924
41MARK21.08744921
42JAK11.05250666
43PAK61.03449999
44MAP3K41.02347597
45CDC71.00387540
46MAP2K31.00328362
47NTRK20.98446376
48MAP3K140.97623223
49FGFR40.97172708
50FGFR10.96567814
51ZAP700.94962861
52CAMKK10.94095526
53RET0.93206665
54SCYL20.92804762
55MAP3K130.89930972
56SIK30.87190536
57CDK90.85034898
58ERN10.83959637
59BLK0.82010563
60DAPK20.80688089
61STK110.80459492
62PTK20.80372503
63CAMK40.79844659
64BMX0.78070207
65CDK40.77921001
66MAPK110.76155450
67RPS6KA20.73887601
68SGK20.73649113
69KSR20.71434919
70PDPK10.70560067
71HCK0.70243042
72BTK0.69457207
73JAK30.69264107
74MAP3K10.69145059
75ITK0.68767428
76PRKD20.68567407
77ERBB20.67092107
78MAPK120.66803717
79STK100.65744402
80MAPK70.65675244
81HIPK20.65287437
82EPHB10.65253568
83* CDC42BPA0.64752154
84RPS6KL10.62050690
85RPS6KC10.62050690
86MAP3K60.61829102
87* CHEK10.60712187
88ATR0.60622539
89SGK10.60353340
90CAMK10.59669447
91PAK20.58969756
92* CDK20.58574040
93KSR10.57971320
94MELK0.57036787
95TAOK30.56968870
96CHUK0.56898660
97* GSK3B0.54759513
98* MAPK140.54692303
99CSK0.54159664
100* MAPK80.53791653
101SGK2230.53371210
102SGK4940.53371210
103CSNK1D0.52050349
104MAP3K20.51666929
105* MAPK100.51580473
106TRPM70.50337572
107JAK20.50261975
108* PRKDC0.50058394
109IRAK40.49145068
110MAP2K20.49111163
111CSNK1A1L0.48986603
112* ATM0.48577374
113NLK0.47964530
114UHMK10.47931823
115LMTK20.47124673
116* RPS6KA30.46356070
117STK30.46347784
118MAPK10.45749127
119RPS6KB20.45655059
120RPS6KA60.45133827
121* CDK10.43652145
122PDK10.43523405
123LATS20.42737541
124MST1R0.41789052
125GRK60.41638750
126FYN0.41471226
127CDK70.40856789
128IRAK30.40711505
129TYK20.39435176
130FES0.39357974
131PRKD10.39299314
132YES10.39164121
133CDK50.38080210
134SRC0.37694434
135LRRK20.37364092
136* CSNK1E0.37162866
137AKT30.36879236
138PRKAA20.36277975
139IKBKE0.35883481
140PRKAA10.35546487
141NEK60.34890662

Predicted pathways (KEGG)

RankGene SetZ-score
1Lysine degradation_Homo sapiens_hsa003102.01897401
2Type II diabetes mellitus_Homo sapiens_hsa049301.75254963
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.65879708
4mTOR signaling pathway_Homo sapiens_hsa041501.56153512
5Thyroid hormone signaling pathway_Homo sapiens_hsa049191.48512451
6Chronic myeloid leukemia_Homo sapiens_hsa052201.46919840
7Long-term potentiation_Homo sapiens_hsa047201.46850623
8Aldosterone synthesis and secretion_Homo sapiens_hsa049251.45765755
9Other glycan degradation_Homo sapiens_hsa005111.45455057
10Dorso-ventral axis formation_Homo sapiens_hsa043201.40719441
11Phosphatidylinositol signaling system_Homo sapiens_hsa040701.36625932
12Thyroid cancer_Homo sapiens_hsa052161.35023397
13Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.30531704
14Glioma_Homo sapiens_hsa052141.25827323
15Neurotrophin signaling pathway_Homo sapiens_hsa047221.24439413
16Notch signaling pathway_Homo sapiens_hsa043301.22929526
17B cell receptor signaling pathway_Homo sapiens_hsa046621.22879805
18Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.21825475
19Circadian entrainment_Homo sapiens_hsa047131.20540739
20T cell receptor signaling pathway_Homo sapiens_hsa046601.19824599
21Endometrial cancer_Homo sapiens_hsa052131.19121200
22Non-small cell lung cancer_Homo sapiens_hsa052231.18464792
23Estrogen signaling pathway_Homo sapiens_hsa049151.15797200
24Adherens junction_Homo sapiens_hsa045201.10968752
25Gastric acid secretion_Homo sapiens_hsa049711.10770311
26Insulin secretion_Homo sapiens_hsa049111.10602316
27Proteoglycans in cancer_Homo sapiens_hsa052051.09723541
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09442295
29Salivary secretion_Homo sapiens_hsa049701.09207685
30MicroRNAs in cancer_Homo sapiens_hsa052061.08683238
31Carbohydrate digestion and absorption_Homo sapiens_hsa049731.07613354
32Colorectal cancer_Homo sapiens_hsa052101.07291307
33GnRH signaling pathway_Homo sapiens_hsa049121.04455901
34Glutamatergic synapse_Homo sapiens_hsa047241.04455509
35Longevity regulating pathway - mammal_Homo sapiens_hsa042111.03752638
36ErbB signaling pathway_Homo sapiens_hsa040121.03095021
37Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.02311798
38Bladder cancer_Homo sapiens_hsa052191.02099311
39Oxytocin signaling pathway_Homo sapiens_hsa049211.01574882
40Nitrogen metabolism_Homo sapiens_hsa009101.01525960
41Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.01181577
42Influenza A_Homo sapiens_hsa051641.00004053
43Insulin resistance_Homo sapiens_hsa049310.99448690
44mRNA surveillance pathway_Homo sapiens_hsa030150.98028870
45Cholinergic synapse_Homo sapiens_hsa047250.97921136
46Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.97705231
47Pancreatic cancer_Homo sapiens_hsa052120.97158186
48Phospholipase D signaling pathway_Homo sapiens_hsa040720.96330614
49Hepatitis C_Homo sapiens_hsa051600.95046654
50Acute myeloid leukemia_Homo sapiens_hsa052210.94998023
51cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94835286
52Leishmaniasis_Homo sapiens_hsa051400.94286020
53VEGF signaling pathway_Homo sapiens_hsa043700.93404973
54Morphine addiction_Homo sapiens_hsa050320.92762226
55Dopaminergic synapse_Homo sapiens_hsa047280.92152144
56Renal cell carcinoma_Homo sapiens_hsa052110.91842337
57cAMP signaling pathway_Homo sapiens_hsa040240.91504992
58Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.91000332
59Olfactory transduction_Homo sapiens_hsa047400.90916292
60Toxoplasmosis_Homo sapiens_hsa051450.90717714
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90415138
62Primary immunodeficiency_Homo sapiens_hsa053400.90199636
63Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.89684614
64Choline metabolism in cancer_Homo sapiens_hsa052310.89506287
65Renin secretion_Homo sapiens_hsa049240.89031142
66MAPK signaling pathway_Homo sapiens_hsa040100.88965828
67Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.88193873
68Measles_Homo sapiens_hsa051620.87839755
69NF-kappa B signaling pathway_Homo sapiens_hsa040640.87703681
70Nicotine addiction_Homo sapiens_hsa050330.87697195
71Basal cell carcinoma_Homo sapiens_hsa052170.87138034
72Inositol phosphate metabolism_Homo sapiens_hsa005620.86832853
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.86248820
74Prolactin signaling pathway_Homo sapiens_hsa049170.85912327
75Osteoclast differentiation_Homo sapiens_hsa043800.85900064
76AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.85437577
77Prion diseases_Homo sapiens_hsa050200.85243915
78Amphetamine addiction_Homo sapiens_hsa050310.85123809
79Toll-like receptor signaling pathway_Homo sapiens_hsa046200.85040670
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.84910622
81Small cell lung cancer_Homo sapiens_hsa052220.84869955
82TNF signaling pathway_Homo sapiens_hsa046680.84678532
83GABAergic synapse_Homo sapiens_hsa047270.83955697
84Platelet activation_Homo sapiens_hsa046110.83046526
85Focal adhesion_Homo sapiens_hsa045100.82859277
86Adipocytokine signaling pathway_Homo sapiens_hsa049200.82031574
87Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.81921603
88Insulin signaling pathway_Homo sapiens_hsa049100.81650748
89Dilated cardiomyopathy_Homo sapiens_hsa054140.81551902
90Viral myocarditis_Homo sapiens_hsa054160.81443498
91Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.81398318
92Wnt signaling pathway_Homo sapiens_hsa043100.80628856
93Prostate cancer_Homo sapiens_hsa052150.80138251
94HIF-1 signaling pathway_Homo sapiens_hsa040660.80064128
95HTLV-I infection_Homo sapiens_hsa051660.79911261
96Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.78923465
97Rap1 signaling pathway_Homo sapiens_hsa040150.78883314
98Melanogenesis_Homo sapiens_hsa049160.78838853
99Chemokine signaling pathway_Homo sapiens_hsa040620.78675331
100Amoebiasis_Homo sapiens_hsa051460.78504243
101Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.78382177
102Glucagon signaling pathway_Homo sapiens_hsa049220.78325421
103Long-term depression_Homo sapiens_hsa047300.77783729
104Herpes simplex infection_Homo sapiens_hsa051680.77031789
105Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.76719271
106FoxO signaling pathway_Homo sapiens_hsa040680.75061351
107Gap junction_Homo sapiens_hsa045400.74965602
108Apoptosis_Homo sapiens_hsa042100.73406990
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.73033606
110Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.72441131
111Thyroid hormone synthesis_Homo sapiens_hsa049180.72319624
112Jak-STAT signaling pathway_Homo sapiens_hsa046300.70162319
113AMPK signaling pathway_Homo sapiens_hsa041520.69873612
114Leukocyte transendothelial migration_Homo sapiens_hsa046700.69702255
115Axon guidance_Homo sapiens_hsa043600.69274434
116Cocaine addiction_Homo sapiens_hsa050300.69249517
117Hippo signaling pathway_Homo sapiens_hsa043900.68808272
118Transcriptional misregulation in cancer_Homo sapiens_hsa052020.68612584
119Hepatitis B_Homo sapiens_hsa051610.67755852
120Synaptic vesicle cycle_Homo sapiens_hsa047210.67031357
121Oocyte meiosis_Homo sapiens_hsa041140.66674937
122Regulation of actin cytoskeleton_Homo sapiens_hsa048100.66627300
123Viral carcinogenesis_Homo sapiens_hsa052030.63780584
124Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62950116
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.62707493
126Tuberculosis_Homo sapiens_hsa051520.60529081
127Pathways in cancer_Homo sapiens_hsa052000.59688327
128Endocytosis_Homo sapiens_hsa041440.56861961
129Epstein-Barr virus infection_Homo sapiens_hsa051690.51877202
130RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45796550

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