Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 5.33450521 |
2 | protein localization to kinetochore (GO:0034501) | 4.79016826 |
3 | nuclear pore complex assembly (GO:0051292) | 4.44498375 |
4 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 4.39310552 |
5 | nuclear pore organization (GO:0006999) | 4.35024930 |
6 | pre-miRNA processing (GO:0031054) | 4.21273265 |
7 | heterochromatin organization (GO:0070828) | 4.17202410 |
8 | DNA duplex unwinding (GO:0032508) | 4.17114691 |
9 | DNA geometric change (GO:0032392) | 4.14943481 |
10 | negative regulation of histone methylation (GO:0031061) | 4.12877528 |
11 | sister chromatid segregation (GO:0000819) | 4.06436385 |
12 | mitotic sister chromatid segregation (GO:0000070) | 4.05570092 |
13 | protein localization to chromosome, centromeric region (GO:0071459) | 4.02768479 |
14 | mitotic nuclear envelope disassembly (GO:0007077) | 3.93880899 |
15 | negative regulation of RNA splicing (GO:0033119) | 3.93509429 |
16 | regulation of histone H3-K9 methylation (GO:0051570) | 3.85569451 |
17 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.84146530 |
18 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.79797876 |
19 | mitotic chromosome condensation (GO:0007076) | 3.79525140 |
20 | negative regulation of mRNA processing (GO:0050686) | 3.77923975 |
21 | regulation of translational fidelity (GO:0006450) | 3.77597968 |
22 | dosage compensation (GO:0007549) | 3.76279486 |
23 | Golgi transport vesicle coating (GO:0048200) | 3.75089648 |
24 | COPI coating of Golgi vesicle (GO:0048205) | 3.75089648 |
25 | nuclear envelope disassembly (GO:0051081) | 3.70071826 |
26 | membrane disassembly (GO:0030397) | 3.70071826 |
27 | DNA replication initiation (GO:0006270) | 3.66276187 |
28 | DNA strand elongation (GO:0022616) | 3.61446126 |
29 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.58767219 |
30 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.51172219 |
31 | negative regulation of mRNA metabolic process (GO:1903312) | 3.50874532 |
32 | chromatin assembly (GO:0031497) | 3.49836771 |
33 | RNA stabilization (GO:0043489) | 3.49050637 |
34 | mRNA stabilization (GO:0048255) | 3.49050637 |
35 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.47902798 |
36 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.47902798 |
37 | regulation of translational termination (GO:0006449) | 3.45956099 |
38 | proline biosynthetic process (GO:0006561) | 3.44534423 |
39 | peptidyl-lysine dimethylation (GO:0018027) | 3.41461785 |
40 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.38831496 |
41 | pore complex assembly (GO:0046931) | 3.38008895 |
42 | IMP biosynthetic process (GO:0006188) | 3.36296576 |
43 | mitotic sister chromatid cohesion (GO:0007064) | 3.35859327 |
44 | DNA conformation change (GO:0071103) | 3.34127347 |
45 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.33544956 |
46 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.33524826 |
47 | ribosomal small subunit biogenesis (GO:0042274) | 3.33157883 |
48 | translesion synthesis (GO:0019985) | 3.30440425 |
49 | formation of translation preinitiation complex (GO:0001731) | 3.28600511 |
50 | nucleosome disassembly (GO:0006337) | 3.24809136 |
51 | protein-DNA complex disassembly (GO:0032986) | 3.24809136 |
52 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.24310866 |
53 | regulation of histone H3-K27 methylation (GO:0061085) | 3.23613763 |
54 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.19403869 |
55 | protein export from nucleus (GO:0006611) | 3.18275514 |
56 | regulation of chromatin binding (GO:0035561) | 3.17191796 |
57 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.13908818 |
58 | apoptotic process involved in morphogenesis (GO:0060561) | 3.13874447 |
59 | regulation of sister chromatid cohesion (GO:0007063) | 3.11170721 |
60 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.10342739 |
61 | regulation of gene silencing by miRNA (GO:0060964) | 3.10128027 |
62 | regulation of gene silencing by RNA (GO:0060966) | 3.10128027 |
63 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.10128027 |
64 | protein complex localization (GO:0031503) | 3.09291208 |
65 | chromatin assembly or disassembly (GO:0006333) | 3.06644492 |
66 | positive regulation of chromosome segregation (GO:0051984) | 3.02405666 |
67 | regulation of RNA export from nucleus (GO:0046831) | 3.02005273 |
68 | regulation of spindle organization (GO:0090224) | 3.01939395 |
69 | nuclear envelope organization (GO:0006998) | 3.01279169 |
70 | chromatin silencing (GO:0006342) | 3.01238035 |
71 | activation of Rac GTPase activity (GO:0032863) | 3.00593978 |
72 | negative regulation of gene expression, epigenetic (GO:0045814) | 3.00233605 |
73 | mitotic recombination (GO:0006312) | 3.00224697 |
74 | negative regulation of cell size (GO:0045792) | 2.99642041 |
75 | DNA replication checkpoint (GO:0000076) | 2.99426443 |
76 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.97623115 |
77 | mRNA splicing, via spliceosome (GO:0000398) | 2.96641493 |
78 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.96641493 |
79 | cellular protein complex localization (GO:0034629) | 2.96487878 |
80 | histone H4-K12 acetylation (GO:0043983) | 2.95518748 |
81 | regulation of mitotic spindle organization (GO:0060236) | 2.95096049 |
82 | telomere maintenance via recombination (GO:0000722) | 2.94717962 |
83 | protein localization to chromosome (GO:0034502) | 2.93624307 |
84 | RNA splicing, via transesterification reactions (GO:0000375) | 2.92192515 |
85 | chromosome condensation (GO:0030261) | 2.91997241 |
86 | termination of RNA polymerase II transcription (GO:0006369) | 2.87916064 |
87 | IMP metabolic process (GO:0046040) | 2.87800492 |
88 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.86244679 |
89 | DNA topological change (GO:0006265) | 2.85457389 |
90 | pentose-phosphate shunt (GO:0006098) | 2.82928473 |
91 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.82784043 |
92 | mitotic metaphase plate congression (GO:0007080) | 2.82601269 |
93 | mRNA transport (GO:0051028) | 2.82209935 |
94 | adherens junction assembly (GO:0034333) | 2.81585125 |
95 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.80107898 |
96 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.78592899 |
97 | regulation of mRNA stability (GO:0043488) | 2.76187087 |
98 | regulation of DNA damage checkpoint (GO:2000001) | 2.75921490 |
99 | positive regulation of RNA splicing (GO:0033120) | 2.74868372 |
100 | gene silencing (GO:0016458) | 2.74613189 |
101 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.73612285 |
102 | ATP-dependent chromatin remodeling (GO:0043044) | 2.73429303 |
103 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.73162531 |
104 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.73105709 |
105 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.73105709 |
106 | histone H4-K5 acetylation (GO:0043981) | 2.72748473 |
107 | histone H4-K8 acetylation (GO:0043982) | 2.72748473 |
108 | focal adhesion assembly (GO:0048041) | 2.72586201 |
109 | cell-substrate adherens junction assembly (GO:0007045) | 2.72586201 |
110 | base-excision repair (GO:0006284) | 2.71084120 |
111 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.70927349 |
112 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.69856156 |
113 | mitotic G1/S transition checkpoint (GO:0044819) | 2.69708496 |
114 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.69067694 |
115 | snRNA metabolic process (GO:0016073) | 2.68854093 |
116 | maternal placenta development (GO:0001893) | 2.68848098 |
117 | histone arginine methylation (GO:0034969) | 2.68022028 |
118 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.67939402 |
119 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.67423390 |
120 | regulation of histone H3-K4 methylation (GO:0051569) | 2.67310588 |
121 | positive regulation of histone deacetylation (GO:0031065) | 2.67111255 |
122 | DNA packaging (GO:0006323) | 2.66292867 |
123 | RNA export from nucleus (GO:0006405) | 2.66094559 |
124 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.65871123 |
125 | mannose metabolic process (GO:0006013) | 2.65807730 |
126 | protein retention in ER lumen (GO:0006621) | 2.65651035 |
127 | telomere maintenance via telomere lengthening (GO:0010833) | 2.65408227 |
128 | rRNA transcription (GO:0009303) | 2.65015471 |
129 | negative regulation of histone modification (GO:0031057) | 2.64972848 |
130 | viral mRNA export from host cell nucleus (GO:0046784) | 2.64896372 |
131 | DNA synthesis involved in DNA repair (GO:0000731) | 2.63334634 |
132 | peptidyl-arginine methylation (GO:0018216) | 2.61173696 |
133 | peptidyl-arginine N-methylation (GO:0035246) | 2.61173696 |
134 | regulation of RNA stability (GO:0043487) | 2.59817732 |
135 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.58852533 |
136 | nuclear envelope reassembly (GO:0031468) | 2.57892777 |
137 | mitotic nuclear envelope reassembly (GO:0007084) | 2.57892777 |
138 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.56954331 |
139 | ribosome biogenesis (GO:0042254) | 2.56325276 |
140 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.56025262 |
141 | modulation by virus of host process (GO:0019054) | 2.55367841 |
142 | histone H3-K36 demethylation (GO:0070544) | 2.54914097 |
143 | establishment of integrated proviral latency (GO:0075713) | 2.53238857 |
144 | folic acid metabolic process (GO:0046655) | 2.51555441 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.81389027 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.05051807 |
3 | MYC_22102868_ChIP-Seq_BL_Human | 3.48121762 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.25490831 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.19434548 |
6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.14706404 |
7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.85698923 |
8 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.72875384 |
9 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.39899263 |
10 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.39578566 |
11 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.23231846 |
12 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.07765659 |
13 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.97837008 |
14 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.91795361 |
15 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.84890530 |
16 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.82955774 |
17 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.79922192 |
18 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.78902257 |
19 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.74251232 |
20 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.73945822 |
21 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.73135217 |
22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.70455748 |
23 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.68402128 |
24 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.66507741 |
25 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.61531147 |
26 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.59394898 |
27 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.57350790 |
28 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.54623208 |
29 | UTX_26944678_Chip-Seq_JUKART_Human | 1.52355675 |
30 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.46628303 |
31 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.46188663 |
32 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45781731 |
33 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.45458274 |
34 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.44462874 |
35 | MAF_26560356_Chip-Seq_TH1_Human | 1.43492340 |
36 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.42805914 |
37 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.42761700 |
38 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.42414089 |
39 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.42283375 |
40 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.40935021 |
41 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39309298 |
42 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.37321549 |
43 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.36989111 |
44 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.36394523 |
45 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.32543093 |
46 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.30447467 |
47 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.29915667 |
48 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.28897460 |
49 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.28480891 |
50 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.28155552 |
51 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.27706140 |
52 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.27574989 |
53 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.27398977 |
54 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.27100305 |
55 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.24535336 |
56 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.23380130 |
57 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.20977208 |
58 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.17977621 |
59 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.17766484 |
60 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.17110255 |
61 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.17075707 |
62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.16523057 |
63 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.15271162 |
64 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.15053296 |
65 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.14736569 |
66 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.14263466 |
67 | MYB_26560356_Chip-Seq_TH1_Human | 1.13919068 |
68 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.13808936 |
69 | KDM2B_26808549_Chip-Seq_K562_Human | 1.13699964 |
70 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.13568274 |
71 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.13327677 |
72 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.13277881 |
73 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.12631235 |
74 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.11550600 |
75 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.11541503 |
76 | MAF_26560356_Chip-Seq_TH2_Human | 1.11086097 |
77 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.10513010 |
78 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.09975901 |
79 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.09698999 |
80 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.08357732 |
81 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.08301054 |
82 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06732752 |
83 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.06129666 |
84 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.05768066 |
85 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.05639691 |
86 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.05256302 |
87 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.04680530 |
88 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.04495761 |
89 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.04032985 |
90 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.03829847 |
91 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.03817266 |
92 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.03778975 |
93 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.03664078 |
94 | MYB_26560356_Chip-Seq_TH2_Human | 1.03559447 |
95 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.02899814 |
96 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.02544173 |
97 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.02033379 |
98 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.01580392 |
99 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.01207967 |
100 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.00725684 |
101 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.99488536 |
102 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.99311790 |
103 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.98838780 |
104 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.98417683 |
105 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.98105746 |
106 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.98034151 |
107 | * BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.96974688 |
108 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.96826218 |
109 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.95994934 |
110 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.94972417 |
111 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.94778487 |
112 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 0.94741137 |
113 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.93769730 |
114 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.92394671 |
115 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.92057786 |
116 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.91030275 |
117 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.90579687 |
118 | ATF3_27146783_Chip-Seq_COLON_Human | 0.90438786 |
119 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.88810733 |
120 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.88176534 |
121 | P68_20966046_ChIP-Seq_HELA_Human | 0.88172543 |
122 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.88016926 |
123 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.85930761 |
124 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.85921449 |
125 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.85580684 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003111_abnormal_nucleus_morphology | 3.74434459 |
2 | MP0010094_abnormal_chromosome_stability | 3.59494937 |
3 | MP0003077_abnormal_cell_cycle | 3.20834098 |
4 | MP0004957_abnormal_blastocyst_morpholog | 3.20628536 |
5 | MP0010352_gastrointestinal_tract_polyps | 3.17786950 |
6 | MP0008057_abnormal_DNA_replication | 3.16960291 |
7 | * MP0003693_abnormal_embryo_hatching | 2.91461247 |
8 | MP0005076_abnormal_cell_differentiation | 2.79942683 |
9 | MP0003705_abnormal_hypodermis_morpholog | 2.68582202 |
10 | MP0002396_abnormal_hematopoietic_system | 2.54125076 |
11 | * MP0001730_embryonic_growth_arrest | 2.34407713 |
12 | MP0005451_abnormal_body_composition | 2.32880420 |
13 | MP0010307_abnormal_tumor_latency | 2.32140079 |
14 | MP0009278_abnormal_bone_marrow | 2.30788988 |
15 | MP0000350_abnormal_cell_proliferation | 2.26316876 |
16 | MP0004808_abnormal_hematopoietic_stem | 2.05316612 |
17 | MP0008058_abnormal_DNA_repair | 2.01037212 |
18 | MP0008007_abnormal_cellular_replicative | 1.97567822 |
19 | MP0001672_abnormal_embryogenesis/_devel | 1.90741324 |
20 | MP0005380_embryogenesis_phenotype | 1.90741324 |
21 | MP0004197_abnormal_fetal_growth/weight/ | 1.88004216 |
22 | MP0003123_paternal_imprinting | 1.81849190 |
23 | MP0003984_embryonic_growth_retardation | 1.79174836 |
24 | MP0002088_abnormal_embryonic_growth/wei | 1.76318929 |
25 | MP0002084_abnormal_developmental_patter | 1.76196205 |
26 | MP0001697_abnormal_embryo_size | 1.75624546 |
27 | MP0008877_abnormal_DNA_methylation | 1.74923579 |
28 | MP0002086_abnormal_extraembryonic_tissu | 1.72585729 |
29 | MP0001545_abnormal_hematopoietic_system | 1.71422146 |
30 | MP0005397_hematopoietic_system_phenotyp | 1.71422146 |
31 | MP0005058_abnormal_lysosome_morphology | 1.69070854 |
32 | MP0002085_abnormal_embryonic_tissue | 1.68644582 |
33 | * MP0002080_prenatal_lethality | 1.68083898 |
34 | MP0000490_abnormal_crypts_of | 1.66269166 |
35 | MP0008260_abnormal_autophagy | 1.63526148 |
36 | MP0000703_abnormal_thymus_morphology | 1.60623228 |
37 | MP0003566_abnormal_cell_adhesion | 1.58934413 |
38 | MP0003453_abnormal_keratinocyte_physiol | 1.56668704 |
39 | MP0001873_stomach_inflammation | 1.55780581 |
40 | MP0000678_abnormal_parathyroid_gland | 1.53497036 |
41 | MP0008932_abnormal_embryonic_tissue | 1.51477663 |
42 | MP0003121_genomic_imprinting | 1.48992091 |
43 | MP0002019_abnormal_tumor_incidence | 1.42557617 |
44 | MP0003300_gastrointestinal_ulcer | 1.42351273 |
45 | * MP0002398_abnormal_bone_marrow | 1.41497886 |
46 | MP0001348_abnormal_lacrimal_gland | 1.40076277 |
47 | * MP0000313_abnormal_cell_death | 1.39587058 |
48 | MP0005501_abnormal_skin_physiology | 1.37526447 |
49 | MP0003303_peritoneal_inflammation | 1.37255119 |
50 | MP0001849_ear_inflammation | 1.35789709 |
51 | MP0004947_skin_inflammation | 1.34842438 |
52 | MP0002796_impaired_skin_barrier | 1.34441624 |
53 | * MP0003763_abnormal_thymus_physiology | 1.29448814 |
54 | MP0004858_abnormal_nervous_system | 1.29279966 |
55 | MP0002653_abnormal_ependyma_morphology | 1.28880130 |
56 | MP0003567_abnormal_fetal_cardiomyocyte | 1.28509151 |
57 | MP0009672_abnormal_birth_weight | 1.28457405 |
58 | MP0002722_abnormal_immune_system | 1.27377159 |
59 | MP0003283_abnormal_digestive_organ | 1.27206117 |
60 | MP0003436_decreased_susceptibility_to | 1.26936450 |
61 | MP0003119_abnormal_digestive_system | 1.25505010 |
62 | MP0000537_abnormal_urethra_morphology | 1.24178606 |
63 | MP0010030_abnormal_orbit_morphology | 1.23817438 |
64 | MP0000003_abnormal_adipose_tissue | 1.22385841 |
65 | MP0003172_abnormal_lysosome_physiology | 1.20430341 |
66 | MP0002249_abnormal_larynx_morphology | 1.18350610 |
67 | MP0000689_abnormal_spleen_morphology | 1.16301686 |
68 | MP0008961_abnormal_basal_metabolism | 1.16250069 |
69 | MP0005666_abnormal_adipose_tissue | 1.15493783 |
70 | MP0000685_abnormal_immune_system | 1.15164913 |
71 | MP0003890_abnormal_embryonic-extraembry | 1.14437279 |
72 | MP0000733_abnormal_muscle_development | 1.14186025 |
73 | MP0005257_abnormal_intraocular_pressure | 1.13773434 |
74 | MP0005023_abnormal_wound_healing | 1.13442491 |
75 | MP0004264_abnormal_extraembryonic_tissu | 1.12799455 |
76 | MP0002009_preneoplasia | 1.12300307 |
77 | MP0003091_abnormal_cell_migration | 1.11376376 |
78 | MP0009703_decreased_birth_body | 1.11308460 |
79 | MP0000569_abnormal_digit_pigmentation | 1.11239847 |
80 | MP0002060_abnormal_skin_morphology | 1.06810677 |
81 | MP0003787_abnormal_imprinting | 1.05176943 |
82 | MP0005375_adipose_tissue_phenotype | 1.02927456 |
83 | MP0003786_premature_aging | 1.02214668 |
84 | MP0001853_heart_inflammation | 1.01677089 |
85 | MP0001915_intracranial_hemorrhage | 1.01302663 |
86 | MP0002925_abnormal_cardiovascular_devel | 1.00630437 |
87 | MP0001293_anophthalmia | 1.00521436 |
88 | MP0002429_abnormal_blood_cell | 0.99343109 |
89 | MP0009053_abnormal_anal_canal | 0.97546145 |
90 | MP0008770_decreased_survivor_rate | 0.97029666 |
91 | MP0009931_abnormal_skin_appearance | 0.96372791 |
92 | MP0005409_darkened_coat_color | 0.95884817 |
93 | MP0000428_abnormal_craniofacial_morphol | 0.95014385 |
94 | MP0010234_abnormal_vibrissa_follicle | 0.94744409 |
95 | MP0009840_abnormal_foam_cell | 0.94111105 |
96 | MP0003115_abnormal_respiratory_system | 0.93351989 |
97 | MP0000716_abnormal_immune_system | 0.92835802 |
98 | MP0001661_extended_life_span | 0.92255765 |
99 | MP0001800_abnormal_humoral_immune | 0.91717167 |
100 | MP0001727_abnormal_embryo_implantation | 0.91603735 |
101 | MP0001216_abnormal_epidermal_layer | 0.91439492 |
102 | MP0005621_abnormal_cell_physiology | 0.90749280 |
103 | MP0001346_abnormal_lacrimal_gland | 0.87813790 |
104 | MP0008438_abnormal_cutaneous_collagen | 0.87640178 |
105 | MP0002877_abnormal_melanocyte_morpholog | 0.84766583 |
106 | MP0002092_abnormal_eye_morphology | 0.84753348 |
107 | MP0010630_abnormal_cardiac_muscle | 0.83034046 |
108 | MP0005384_cellular_phenotype | 0.82785535 |
109 | MP0005623_abnormal_meninges_morphology | 0.82610514 |
110 | MP0000477_abnormal_intestine_morphology | 0.81466915 |
111 | MP0003315_abnormal_perineum_morphology | 0.80437194 |
112 | MP0000371_diluted_coat_color | 0.79926545 |
113 | MP0000858_altered_metastatic_potential | 0.79629009 |
114 | MP0000266_abnormal_heart_morphology | 0.78942278 |
115 | MP0000747_muscle_weakness | 0.78223800 |
116 | MP0002405_respiratory_system_inflammati | 0.78166572 |
117 | MP0003866_abnormal_defecation | 0.77234586 |
118 | MP0002166_altered_tumor_susceptibility | 0.77057579 |
119 | MP0002697_abnormal_eye_size | 0.75442946 |
120 | MP0002970_abnormal_white_adipose | 0.75091591 |
121 | MP0006054_spinal_hemorrhage | 0.74395921 |
122 | MP0003935_abnormal_craniofacial_develop | 0.73459580 |
123 | MP0002089_abnormal_postnatal_growth/wei | 0.73454819 |
124 | MP0001784_abnormal_fluid_regulation | 0.73090015 |
125 | MP0002210_abnormal_sex_determination | 0.71930776 |
126 | MP0002111_abnormal_tail_morphology | 0.71311644 |
127 | MP0004185_abnormal_adipocyte_glucose | 0.71153849 |
128 | MP0004233_abnormal_muscle_weight | 0.71078187 |
129 | MP0002420_abnormal_adaptive_immunity | 0.70820785 |
130 | MP0001145_abnormal_male_reproductive | 0.70252133 |
131 | MP0001819_abnormal_immune_cell | 0.68952531 |
132 | MP0002452_abnormal_antigen_presenting | 0.67235484 |
133 | MP0004510_myositis | 0.65830907 |
134 | MP0003221_abnormal_cardiomyocyte_apopto | 0.65275032 |
135 | MP0010155_abnormal_intestine_physiology | 0.64332626 |
136 | * MP0009333_abnormal_splenocyte_physiolog | 0.63288883 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 3.64086516 |
2 | Hyperacusis (HP:0010780) | 3.50242496 |
3 | Selective tooth agenesis (HP:0001592) | 3.20079333 |
4 | Increased nuchal translucency (HP:0010880) | 2.98956341 |
5 | Abnormality of the fingertips (HP:0001211) | 2.95390233 |
6 | Basal cell carcinoma (HP:0002671) | 2.85136954 |
7 | Astrocytoma (HP:0009592) | 2.81934678 |
8 | Abnormality of the astrocytes (HP:0100707) | 2.81934678 |
9 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.81592582 |
10 | Short 4th metacarpal (HP:0010044) | 2.81592582 |
11 | Renal duplication (HP:0000075) | 2.67259602 |
12 | Progressive muscle weakness (HP:0003323) | 2.60436646 |
13 | Cerebral aneurysm (HP:0004944) | 2.60082879 |
14 | Medulloblastoma (HP:0002885) | 2.59671132 |
15 | Abnormality of the lower motor neuron (HP:0002366) | 2.56873066 |
16 | Broad face (HP:0000283) | 2.54946226 |
17 | Long palpebral fissure (HP:0000637) | 2.51578142 |
18 | Achilles tendon contracture (HP:0001771) | 2.50036260 |
19 | Abnormal number of incisors (HP:0011064) | 2.49676934 |
20 | Volvulus (HP:0002580) | 2.49649165 |
21 | High pitched voice (HP:0001620) | 2.48786048 |
22 | Prominent nose (HP:0000448) | 2.43483151 |
23 | Distal lower limb amyotrophy (HP:0008944) | 2.43205477 |
24 | Insomnia (HP:0100785) | 2.41305186 |
25 | Long eyelashes (HP:0000527) | 2.41089663 |
26 | Elfin facies (HP:0004428) | 2.38307925 |
27 | Proximal placement of thumb (HP:0009623) | 2.37951220 |
28 | Broad distal phalanx of finger (HP:0009836) | 2.37755312 |
29 | Deviation of the thumb (HP:0009603) | 2.34343058 |
30 | Renovascular hypertension (HP:0100817) | 2.33276842 |
31 | Deep palmar crease (HP:0006191) | 2.32555410 |
32 | Skin tags (HP:0010609) | 2.31850797 |
33 | Disproportionate tall stature (HP:0001519) | 2.31696811 |
34 | Obstructive sleep apnea (HP:0002870) | 2.30871061 |
35 | Neoplasm of the oral cavity (HP:0100649) | 2.30168353 |
36 | Trismus (HP:0000211) | 2.27939812 |
37 | Colon cancer (HP:0003003) | 2.26907251 |
38 | Ulnar bowing (HP:0003031) | 2.24527711 |
39 | Neoplasm of striated muscle (HP:0009728) | 2.24010219 |
40 | Metaphyseal cupping (HP:0003021) | 2.22570138 |
41 | Rhabdomyosarcoma (HP:0002859) | 2.21970419 |
42 | Asymmetry of the thorax (HP:0001555) | 2.21583104 |
43 | Glioma (HP:0009733) | 2.20194115 |
44 | Increased density of long bones (HP:0006392) | 2.16745230 |
45 | Pointed chin (HP:0000307) | 2.16349475 |
46 | Abnormality of the Achilles tendon (HP:0005109) | 2.16290800 |
47 | Microvesicular hepatic steatosis (HP:0001414) | 2.14606660 |
48 | Broad palm (HP:0001169) | 2.13133074 |
49 | Biconcave vertebral bodies (HP:0004586) | 2.13101172 |
50 | Preauricular skin tag (HP:0000384) | 2.11704433 |
51 | Progressive external ophthalmoplegia (HP:0000590) | 2.10619720 |
52 | Pseudobulbar signs (HP:0002200) | 2.10609553 |
53 | Missing ribs (HP:0000921) | 2.09783760 |
54 | Heterotopia (HP:0002282) | 2.08222339 |
55 | Patellar aplasia (HP:0006443) | 2.07993823 |
56 | Patellar dislocation (HP:0002999) | 2.06991568 |
57 | Abnormality of the 4th metacarpal (HP:0010012) | 2.05275128 |
58 | Premature rupture of membranes (HP:0001788) | 2.02048533 |
59 | Cafe-au-lait spot (HP:0000957) | 2.00847107 |
60 | Flat acetabular roof (HP:0003180) | 1.99951252 |
61 | Bowel diverticulosis (HP:0005222) | 1.99239249 |
62 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.99235041 |
63 | Ankyloglossia (HP:0010296) | 1.99219959 |
64 | Overriding aorta (HP:0002623) | 1.99188714 |
65 | Cholecystitis (HP:0001082) | 1.97995691 |
66 | Abnormal gallbladder physiology (HP:0012438) | 1.97995691 |
67 | Gastrointestinal carcinoma (HP:0002672) | 1.97484219 |
68 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.97484219 |
69 | Abnormality of the anterior horn cell (HP:0006802) | 1.97314620 |
70 | Degeneration of anterior horn cells (HP:0002398) | 1.97314620 |
71 | Spinal muscular atrophy (HP:0007269) | 1.97289890 |
72 | Abnormality of the thoracic spine (HP:0100711) | 1.96993692 |
73 | Sparse lateral eyebrow (HP:0005338) | 1.95939401 |
74 | Reticulocytosis (HP:0001923) | 1.94784055 |
75 | Increased connective tissue (HP:0009025) | 1.94750225 |
76 | Ragged-red muscle fibers (HP:0003200) | 1.93964957 |
77 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.93937396 |
78 | High anterior hairline (HP:0009890) | 1.93499358 |
79 | Flared metaphyses (HP:0003015) | 1.93123473 |
80 | Dysmetric saccades (HP:0000641) | 1.91925615 |
81 | Hand muscle atrophy (HP:0009130) | 1.91524115 |
82 | Reticulocytopenia (HP:0001896) | 1.90943757 |
83 | Cellulitis (HP:0100658) | 1.88415648 |
84 | Angiofibromas (HP:0010615) | 1.87937522 |
85 | Adenoma sebaceum (HP:0009720) | 1.87937522 |
86 | Myelodysplasia (HP:0002863) | 1.87603465 |
87 | Thin bony cortex (HP:0002753) | 1.86940637 |
88 | Protrusio acetabuli (HP:0003179) | 1.86308434 |
89 | Trigonocephaly (HP:0000243) | 1.85393314 |
90 | Thrombocytosis (HP:0001894) | 1.83830900 |
91 | Upper limb amyotrophy (HP:0009129) | 1.83656526 |
92 | Distal upper limb amyotrophy (HP:0007149) | 1.83656526 |
93 | Vertebral compression fractures (HP:0002953) | 1.82909437 |
94 | Broad thumb (HP:0011304) | 1.82850068 |
95 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.81306625 |
96 | Abnormality of the calcaneus (HP:0008364) | 1.81076593 |
97 | Ectopic kidney (HP:0000086) | 1.80368022 |
98 | Recurrent viral infections (HP:0004429) | 1.80127967 |
99 | Dislocated radial head (HP:0003083) | 1.79516521 |
100 | Sandal gap (HP:0001852) | 1.79143356 |
101 | Chromsome breakage (HP:0040012) | 1.78962119 |
102 | Rib fusion (HP:0000902) | 1.78871544 |
103 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.78178371 |
104 | Macroorchidism (HP:0000053) | 1.78087254 |
105 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.77880596 |
106 | Acute lymphatic leukemia (HP:0006721) | 1.77763591 |
107 | Atresia of the external auditory canal (HP:0000413) | 1.75854891 |
108 | Impulsivity (HP:0100710) | 1.75565109 |
109 | Cutis marmorata (HP:0000965) | 1.74194254 |
110 | Bicuspid aortic valve (HP:0001647) | 1.74026019 |
111 | Squamous cell carcinoma (HP:0002860) | 1.73250503 |
112 | Thin ribs (HP:0000883) | 1.72460524 |
113 | Shallow orbits (HP:0000586) | 1.72130833 |
114 | Obsessive-compulsive behavior (HP:0000722) | 1.71728988 |
115 | Colitis (HP:0002583) | 1.71632690 |
116 | Vertebral arch anomaly (HP:0008438) | 1.70138571 |
117 | Abnormal number of erythroid precursors (HP:0012131) | 1.69526820 |
118 | 11 pairs of ribs (HP:0000878) | 1.69007983 |
119 | Thoracic kyphosis (HP:0002942) | 1.68417994 |
120 | Cutaneous melanoma (HP:0012056) | 1.67506844 |
121 | Verrucae (HP:0200043) | 1.67191333 |
122 | Papilloma (HP:0012740) | 1.67191333 |
123 | Rectal prolapse (HP:0002035) | 1.67045168 |
124 | Premature skin wrinkling (HP:0100678) | 1.66773860 |
125 | Short 5th finger (HP:0009237) | 1.66562191 |
126 | Abnormality of the radial head (HP:0003995) | 1.66205176 |
127 | Myopathic facies (HP:0002058) | 1.66143318 |
128 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.65912392 |
129 | Gastrointestinal inflammation (HP:0004386) | 1.65487856 |
130 | Urethral obstruction (HP:0000796) | 1.65244437 |
131 | Fatigue (HP:0012378) | 1.64922060 |
132 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.64313481 |
133 | Broad phalanges of the hand (HP:0009768) | 1.64017408 |
134 | Neoplasm of the pancreas (HP:0002894) | 1.63635698 |
135 | Hemorrhage of the eye (HP:0011885) | 1.63108330 |
136 | Fibrous tissue neoplasm (HP:0012316) | 1.62998758 |
137 | Turricephaly (HP:0000262) | 1.62332499 |
138 | Fibroma (HP:0010614) | 1.62303369 |
139 | Syringomyelia (HP:0003396) | 1.61953753 |
140 | Spinal cord lesions (HP:0100561) | 1.61953753 |
141 | Flat cornea (HP:0007720) | 1.61850224 |
142 | Abnormality of the carotid arteries (HP:0005344) | 1.61310188 |
143 | Overlapping toe (HP:0001845) | 1.60732936 |
144 | Birth length less than 3rd percentile (HP:0003561) | 1.60338003 |
145 | Multiple enchondromatosis (HP:0005701) | 1.60215941 |
146 | Abnormality of oral frenula (HP:0000190) | 1.59906147 |
147 | Skull defect (HP:0001362) | 1.59782129 |
148 | Abnormality of reticulocytes (HP:0004312) | 1.59399217 |
149 | Poikiloderma (HP:0001029) | 1.59192594 |
150 | Lower limb amyotrophy (HP:0007210) | 1.59144696 |
151 | Hypertensive crisis (HP:0100735) | 1.58470038 |
152 | Deep philtrum (HP:0002002) | 1.56397525 |
153 | Glossoptosis (HP:0000162) | 1.56050320 |
154 | Seborrheic dermatitis (HP:0001051) | 1.56029533 |
155 | Abnormality of the columella (HP:0009929) | 1.54512295 |
156 | Spina bifida occulta (HP:0003298) | 1.54395597 |
157 | Rough bone trabeculation (HP:0100670) | 1.54216593 |
158 | Truncus arteriosus (HP:0001660) | 1.53431386 |
159 | Polygenic inheritance (HP:0010982) | 1.52775974 |
160 | Persistence of primary teeth (HP:0006335) | 1.52538784 |
161 | Fragile skin (HP:0001030) | 1.52522437 |
162 | J-shaped sella turcica (HP:0002680) | 1.52282813 |
163 | Bowel incontinence (HP:0002607) | 1.51749127 |
164 | Cupped ribs (HP:0000887) | 1.51718575 |
165 | Stridor (HP:0010307) | 1.51708886 |
166 | Progressive hearing impairment (HP:0001730) | 1.50611743 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SMG1 | 4.42388853 |
2 | EEF2K | 3.98793073 |
3 | MAP3K10 | 3.88541427 |
4 | CDK12 | 3.83081968 |
5 | CDC7 | 3.59100314 |
6 | PKN2 | 3.01006352 |
7 | TRIB3 | 3.00722409 |
8 | PRPF4B | 2.94461904 |
9 | NEK2 | 2.90762009 |
10 | NME2 | 2.21810708 |
11 | MAP4K1 | 2.04188236 |
12 | IRAK3 | 1.99885567 |
13 | WEE1 | 1.92238185 |
14 | ICK | 1.90874526 |
15 | RPS6KB2 | 1.80312044 |
16 | FGFR4 | 1.80260472 |
17 | STK10 | 1.72863395 |
18 | BUB1 | 1.69522934 |
19 | ALK | 1.66251420 |
20 | SIK2 | 1.66032914 |
21 | CDK4 | 1.63999785 |
22 | PASK | 1.60117716 |
23 | TTK | 1.58828582 |
24 | GRK6 | 1.49752194 |
25 | ATR | 1.46177129 |
26 | RIPK1 | 1.45988586 |
27 | BRD4 | 1.45435244 |
28 | CDK7 | 1.39730893 |
29 | ERN1 | 1.36851269 |
30 | NEK1 | 1.36040788 |
31 | PAK4 | 1.35664991 |
32 | SCYL2 | 1.34767458 |
33 | MTOR | 1.27953612 |
34 | PTK6 | 1.26224985 |
35 | TTN | 1.26213127 |
36 | CHEK1 | 1.25432859 |
37 | MAP3K8 | 1.23213400 |
38 | LRRK2 | 1.22703750 |
39 | PLK1 | 1.16962823 |
40 | MAP3K13 | 1.16688615 |
41 | VRK2 | 1.14297545 |
42 | CDK6 | 1.13956431 |
43 | PDGFRA | 1.11576526 |
44 | AURKB | 1.07480846 |
45 | TAOK2 | 1.07350737 |
46 | RPS6KA4 | 1.06000807 |
47 | TSSK6 | 1.02176572 |
48 | SRPK1 | 1.01881648 |
49 | MAP2K3 | 1.01470586 |
50 | STK4 | 1.00317488 |
51 | TESK2 | 0.99592440 |
52 | CDK9 | 0.98407405 |
53 | FLT3 | 0.93295571 |
54 | * CDK2 | 0.91957211 |
55 | CHEK2 | 0.89384838 |
56 | TAOK1 | 0.89381894 |
57 | TYRO3 | 0.87926059 |
58 | SIK1 | 0.87384588 |
59 | BMX | 0.86490806 |
60 | MAP3K14 | 0.84598816 |
61 | PIM1 | 0.83597997 |
62 | ATM | 0.81888599 |
63 | MST1R | 0.81684967 |
64 | BRAF | 0.81606773 |
65 | SIK3 | 0.80980480 |
66 | DYRK3 | 0.80876506 |
67 | TGFBR1 | 0.79326935 |
68 | CAMK1D | 0.77970806 |
69 | LATS2 | 0.75910609 |
70 | KSR2 | 0.74716694 |
71 | BTK | 0.73210362 |
72 | CSF1R | 0.73154099 |
73 | BRSK1 | 0.71957204 |
74 | KDR | 0.70489490 |
75 | MAP2K2 | 0.68492546 |
76 | ARAF | 0.67832876 |
77 | MKNK1 | 0.66754759 |
78 | PAK2 | 0.66172366 |
79 | ZAP70 | 0.61991986 |
80 | MAPKAPK3 | 0.59679736 |
81 | RIPK4 | 0.59434278 |
82 | CAMK1G | 0.59060259 |
83 | * CDK1 | 0.58070473 |
84 | CDK8 | 0.57968141 |
85 | AURKA | 0.57534258 |
86 | DYRK1B | 0.56308316 |
87 | ACVR1B | 0.55658949 |
88 | PRKD2 | 0.55657983 |
89 | BRSK2 | 0.55545767 |
90 | AKT2 | 0.53852399 |
91 | PRKD3 | 0.53338347 |
92 | CSK | 0.52635896 |
93 | STK3 | 0.52117289 |
94 | MAP3K1 | 0.51271447 |
95 | CLK1 | 0.51075411 |
96 | MAPK11 | 0.51044529 |
97 | MAP3K11 | 0.50737087 |
98 | JAK3 | 0.50490413 |
99 | TESK1 | 0.48755221 |
100 | PDPK1 | 0.47182588 |
101 | PRKDC | 0.45967627 |
102 | PTK2 | 0.45890584 |
103 | EPHA2 | 0.45842851 |
104 | HCK | 0.45756730 |
105 | TLK1 | 0.45412300 |
106 | HIPK2 | 0.44739556 |
107 | RPS6KA1 | 0.44400760 |
108 | MELK | 0.44313777 |
109 | MAPK14 | 0.44268793 |
110 | PIM2 | 0.43537679 |
111 | TBK1 | 0.43445138 |
112 | DMPK | 0.43175097 |
113 | RPS6KA2 | 0.42909977 |
114 | EIF2AK1 | 0.42500997 |
115 | IRAK2 | 0.42271522 |
116 | TYK2 | 0.41537565 |
117 | PDGFRB | 0.40771081 |
118 | CDC42BPA | 0.40227498 |
119 | CSNK1E | 0.39644085 |
120 | PBK | 0.39446088 |
121 | MAP3K7 | 0.39042236 |
122 | MARK2 | 0.38373958 |
123 | RPS6KC1 | 0.38151426 |
124 | RPS6KL1 | 0.38151426 |
125 | PAK1 | 0.38121609 |
126 | MKNK2 | 0.38000118 |
127 | RET | 0.37262081 |
128 | MARK3 | 0.37194463 |
129 | IRAK4 | 0.36941634 |
130 | CDK11A | 0.36752418 |
131 | PLK3 | 0.36088025 |
132 | CSNK2A2 | 0.35924692 |
133 | CSNK1D | 0.35672034 |
134 | RPS6KA6 | 0.33197378 |
135 | MAPKAPK2 | 0.31615821 |
136 | TAF1 | 0.30709349 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.04951984 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.32309653 |
3 | Spliceosome_Homo sapiens_hsa03040 | 3.02517503 |
4 | RNA transport_Homo sapiens_hsa03013 | 2.63015305 |
5 | Base excision repair_Homo sapiens_hsa03410 | 2.59139747 |
6 | Cell cycle_Homo sapiens_hsa04110 | 2.42993335 |
7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.32289173 |
8 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.30884438 |
9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.28940207 |
10 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.01397924 |
11 | Homologous recombination_Homo sapiens_hsa03440 | 1.90592718 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.77303559 |
13 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.75911623 |
14 | Other glycan degradation_Homo sapiens_hsa00511 | 1.75644415 |
15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.66554580 |
16 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.63480543 |
17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.47648868 |
18 | Lysine degradation_Homo sapiens_hsa00310 | 1.46407207 |
19 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.46405545 |
20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.42421692 |
21 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.40190831 |
22 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.33467092 |
23 | RNA degradation_Homo sapiens_hsa03018 | 1.33225174 |
24 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.31224438 |
25 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.30999955 |
26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.30956340 |
27 | HTLV-I infection_Homo sapiens_hsa05166 | 1.30439255 |
28 | Ribosome_Homo sapiens_hsa03010 | 1.29893042 |
29 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.29332138 |
30 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.24480228 |
31 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.21756212 |
32 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.20917924 |
33 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.18470999 |
34 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.18195356 |
35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.17902798 |
36 | Prion diseases_Homo sapiens_hsa05020 | 1.17028123 |
37 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.16996353 |
38 | Colorectal cancer_Homo sapiens_hsa05210 | 1.14301648 |
39 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.12529764 |
40 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.11456340 |
41 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.10809692 |
42 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.07597030 |
43 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.05632633 |
44 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.05592358 |
45 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.02631015 |
46 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.00861253 |
47 | Thyroid cancer_Homo sapiens_hsa05216 | 0.98015666 |
48 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.97407290 |
49 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.96723396 |
50 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.93892150 |
51 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.92446898 |
52 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.90669305 |
53 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.90463530 |
54 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.88845400 |
55 | Bladder cancer_Homo sapiens_hsa05219 | 0.88572528 |
56 | Apoptosis_Homo sapiens_hsa04210 | 0.87854944 |
57 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.87155743 |
58 | Adherens junction_Homo sapiens_hsa04520 | 0.86647429 |
59 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.85290130 |
60 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.85196178 |
61 | Hepatitis B_Homo sapiens_hsa05161 | 0.85044889 |
62 | Endometrial cancer_Homo sapiens_hsa05213 | 0.83760137 |
63 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.81654329 |
64 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.81412852 |
65 | Carbon metabolism_Homo sapiens_hsa01200 | 0.80793208 |
66 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.79684654 |
67 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.79476392 |
68 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.79468644 |
69 | Hepatitis C_Homo sapiens_hsa05160 | 0.79238661 |
70 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.77945149 |
71 | Viral myocarditis_Homo sapiens_hsa05416 | 0.76444109 |
72 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.74670816 |
73 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.74589119 |
74 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.70118887 |
75 | Galactose metabolism_Homo sapiens_hsa00052 | 0.69364362 |
76 | Shigellosis_Homo sapiens_hsa05131 | 0.69238088 |
77 | Glioma_Homo sapiens_hsa05214 | 0.69019041 |
78 | Measles_Homo sapiens_hsa05162 | 0.67893271 |
79 | Prostate cancer_Homo sapiens_hsa05215 | 0.65307943 |
80 | Pathways in cancer_Homo sapiens_hsa05200 | 0.64900873 |
81 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.63867607 |
82 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.63223209 |
83 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.63074705 |
84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.62964603 |
85 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.62863709 |
86 | Salmonella infection_Homo sapiens_hsa05132 | 0.62547676 |
87 | Alcoholism_Homo sapiens_hsa05034 | 0.62465617 |
88 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.60014524 |
89 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.60005984 |
90 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.59558389 |
91 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.59455761 |
92 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.59371870 |
93 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.58535099 |
94 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.56988575 |
95 | Legionellosis_Homo sapiens_hsa05134 | 0.56870876 |
96 | RNA polymerase_Homo sapiens_hsa03020 | 0.56294647 |
97 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.55785679 |
98 | Influenza A_Homo sapiens_hsa05164 | 0.55633964 |
99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.55166286 |
100 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.54440332 |
101 | Leishmaniasis_Homo sapiens_hsa05140 | 0.54411737 |
102 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.52707296 |
103 | Focal adhesion_Homo sapiens_hsa04510 | 0.52155630 |
104 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.51080437 |
105 | Platelet activation_Homo sapiens_hsa04611 | 0.50532708 |
106 | Basal transcription factors_Homo sapiens_hsa03022 | 0.48944071 |
107 | Insulin resistance_Homo sapiens_hsa04931 | 0.48783750 |
108 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.48337045 |
109 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.48178047 |
110 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.47069311 |
111 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.46609409 |
112 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.46355840 |
113 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.45890798 |
114 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.45154022 |
115 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.44998594 |
116 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.44577685 |
117 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.44011113 |
118 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.43216798 |
119 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.42193698 |
120 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.42133393 |
121 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.39472714 |
122 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.37629944 |
123 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.36483277 |
124 | Sulfur relay system_Homo sapiens_hsa04122 | 0.36331633 |
125 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.35890655 |