SSBP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.72874068
2regulation of synaptic vesicle exocytosis (GO:2000300)4.71567590
3glutamate secretion (GO:0014047)4.53782764
4synaptic vesicle exocytosis (GO:0016079)4.41334851
5cerebellar granule cell differentiation (GO:0021707)4.38975203
6postsynaptic membrane organization (GO:0001941)4.38652115
7vocalization behavior (GO:0071625)4.38335529
8cell migration in hindbrain (GO:0021535)4.35091965
9presynaptic membrane organization (GO:0097090)4.17744926
10locomotory exploration behavior (GO:0035641)4.17704424
11regulation of synaptic vesicle transport (GO:1902803)3.95759969
12presynaptic membrane assembly (GO:0097105)3.92468137
13neuronal ion channel clustering (GO:0045161)3.90731350
14exploration behavior (GO:0035640)3.88303662
15membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.86762023
16axon ensheathment in central nervous system (GO:0032291)3.81676948
17central nervous system myelination (GO:0022010)3.81676948
18neurotransmitter secretion (GO:0007269)3.81465623
19peptidyl-arginine omega-N-methylation (GO:0035247)3.76627348
20ionotropic glutamate receptor signaling pathway (GO:0035235)3.76602204
21regulation of glutamate receptor signaling pathway (GO:1900449)3.74823413
22regulation of neuronal synaptic plasticity (GO:0048168)3.73135458
23positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.69271272
24nucleosome disassembly (GO:0006337)3.61937427
25protein-DNA complex disassembly (GO:0032986)3.61937427
26peptidyl-arginine N-methylation (GO:0035246)3.61054843
27peptidyl-arginine methylation (GO:0018216)3.61054843
28pre-miRNA processing (GO:0031054)3.58493117
29cellular potassium ion homeostasis (GO:0030007)3.57561930
30planar cell polarity pathway involved in neural tube closure (GO:0090179)3.55819380
31transmission of nerve impulse (GO:0019226)3.53935615
32paraxial mesoderm development (GO:0048339)3.51860864
33establishment of mitochondrion localization (GO:0051654)3.43099081
34sodium ion export (GO:0071436)3.38959606
35neurotransmitter-gated ion channel clustering (GO:0072578)3.38314530
36synaptic transmission, glutamatergic (GO:0035249)3.37736247
37glucocorticoid receptor signaling pathway (GO:0042921)3.36413572
38nucleobase catabolic process (GO:0046113)3.35562297
39cell differentiation in hindbrain (GO:0021533)3.33224086
40regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.31552709
41positive regulation of dendritic spine morphogenesis (GO:0061003)3.30916419
42neuromuscular process controlling balance (GO:0050885)3.30833410
43regulation of long-term neuronal synaptic plasticity (GO:0048169)3.30158957
44mitochondrion transport along microtubule (GO:0047497)3.26422531
45establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.26422531
46regulation of synapse structural plasticity (GO:0051823)3.26227460
47negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.25210499
48regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.23701364
49positive regulation of membrane potential (GO:0045838)3.23517107
50regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.21376590
51layer formation in cerebral cortex (GO:0021819)3.19463636
52auditory behavior (GO:0031223)3.17825918
53adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.13586564
54negative regulation of microtubule polymerization (GO:0031115)3.11705898
55regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.09016462
56neurotransmitter transport (GO:0006836)3.07050155
57glial cell proliferation (GO:0014009)3.05594327
58positive regulation of dendritic spine development (GO:0060999)3.04686214
59glutamate receptor signaling pathway (GO:0007215)2.99926031
60histone arginine methylation (GO:0034969)2.99314178
61negative regulation of RNA splicing (GO:0033119)2.94438825
62regulation of excitatory postsynaptic membrane potential (GO:0060079)2.94130834
63synaptic vesicle endocytosis (GO:0048488)2.93817815
64neuron-neuron synaptic transmission (GO:0007270)2.93228568
65regulation of NFAT protein import into nucleus (GO:0051532)2.92995044
66cerebral cortex radially oriented cell migration (GO:0021799)2.91794197
67body morphogenesis (GO:0010171)2.91747367
68dendritic spine organization (GO:0097061)2.88886415
69mRNA splice site selection (GO:0006376)2.88861814
70axonal fasciculation (GO:0007413)2.87100763
71dopamine receptor signaling pathway (GO:0007212)2.86728061
72regulation of postsynaptic membrane potential (GO:0060078)2.86673715
73negative regulation of axonogenesis (GO:0050771)2.86364175
74substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.85753514
75substrate-independent telencephalic tangential migration (GO:0021826)2.85753514
76positive regulation of synapse assembly (GO:0051965)2.84766482
77adult walking behavior (GO:0007628)2.84057235
78cell communication by electrical coupling (GO:0010644)2.83911708
79regulation of synapse maturation (GO:0090128)2.83709705
80apical protein localization (GO:0045176)2.83439956
81pyrimidine nucleobase catabolic process (GO:0006208)2.83026077
82synaptic vesicle docking involved in exocytosis (GO:0016081)2.82467298
83response to auditory stimulus (GO:0010996)2.80572284
84camera-type eye morphogenesis (GO:0048593)2.80163690
85regulation of neurotransmitter secretion (GO:0046928)2.79579593
86mechanosensory behavior (GO:0007638)2.79241047
87G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.78744559
88proximal/distal pattern formation (GO:0009954)2.77432001
89potassium ion homeostasis (GO:0055075)2.75480582
90regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.75334816
91negative regulation of mRNA processing (GO:0050686)2.74385644
92central nervous system projection neuron axonogenesis (GO:0021952)2.73335902
93cell-cell junction maintenance (GO:0045217)2.72730368
94cerebellar Purkinje cell layer development (GO:0021680)2.70890536
95mating behavior (GO:0007617)2.70772777
96outer ear morphogenesis (GO:0042473)2.70480237
97innervation (GO:0060384)2.70201843
98regulation of glycogen (starch) synthase activity (GO:2000465)2.69638028
99spinal cord association neuron differentiation (GO:0021527)2.69323401
100spinal cord development (GO:0021510)2.69077853
101neurofilament cytoskeleton organization (GO:0060052)2.68360073
102cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.68204059
103regulation of neurotransmitter levels (GO:0001505)2.67390257
104regulation of hippo signaling (GO:0035330)2.66955704
105synapse assembly (GO:0007416)2.65941111
106neuronal action potential propagation (GO:0019227)2.65884063
107regulation of vesicle fusion (GO:0031338)2.65724892
108positive regulation of RNA splicing (GO:0033120)2.65530062
109positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.64302594
110neuromuscular synaptic transmission (GO:0007274)2.61608869
111gastrulation with mouth forming second (GO:0001702)2.61591424
112neuron recognition (GO:0008038)2.60759904
113hippo signaling (GO:0035329)2.58679227
114neuromuscular process (GO:0050905)2.58048342
115regulation of synaptic plasticity (GO:0048167)2.56934844
116synaptic vesicle maturation (GO:0016188)2.56821667
117positive regulation of gastrulation (GO:2000543)2.50990070
118DNA unwinding involved in DNA replication (GO:0006268)2.49004835
119dendritic spine morphogenesis (GO:0060997)2.48533346
120cerebellar Purkinje cell differentiation (GO:0021702)2.48464812
121polarized epithelial cell differentiation (GO:0030859)2.48054985
122lateral sprouting from an epithelium (GO:0060601)2.44974986
123metanephric mesenchyme development (GO:0072075)2.44871958
124cochlea morphogenesis (GO:0090103)2.42968743
125regulation of mRNA splicing, via spliceosome (GO:0048024)2.42492796
126generation of neurons (GO:0048699)2.42475426
127peptidyl-lysine dimethylation (GO:0018027)2.42210255
128head development (GO:0060322)2.41902167
129dendrite morphogenesis (GO:0048813)2.39585627
130sympathetic nervous system development (GO:0048485)2.39246121
131establishment or maintenance of monopolar cell polarity (GO:0061339)2.38801285
132establishment of monopolar cell polarity (GO:0061162)2.38801285
133negative regulation of mRNA metabolic process (GO:1903312)2.37927900
134Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.37885915
135embryonic body morphogenesis (GO:0010172)2.35956512
136cranial nerve morphogenesis (GO:0021602)2.35512363
137corticosteroid receptor signaling pathway (GO:0031958)2.35390168
138embryonic foregut morphogenesis (GO:0048617)2.35042867
139kidney mesenchyme development (GO:0072074)2.34793476
140regulation of chromatin binding (GO:0035561)2.34638693
141establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.33338695
142positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.32257600
143positive regulation of cell cycle G2/M phase transition (GO:1902751)2.32257600
144embryonic hindlimb morphogenesis (GO:0035116)2.31980156
145regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.30846843
146regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.29065683
147genetic imprinting (GO:0071514)2.28586417
148hindlimb morphogenesis (GO:0035137)2.28328946
149regulation of establishment of planar polarity (GO:0090175)2.28242440
150G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.28065940
151regulation of stem cell maintenance (GO:2000036)2.26613437
152axon extension (GO:0048675)2.26054412
153establishment of tissue polarity (GO:0007164)2.25856425
154establishment of planar polarity (GO:0001736)2.25856425
155negative regulation of histone methylation (GO:0031061)2.25307559
156intracellular estrogen receptor signaling pathway (GO:0030520)2.24197050
157negative regulation of axon extension involved in axon guidance (GO:0048843)2.22612463
158negative regulation of catenin import into nucleus (GO:0035414)2.21695178
159neuron cell-cell adhesion (GO:0007158)2.19440018
160regulation of gene silencing by RNA (GO:0060966)2.18960089
161regulation of posttranscriptional gene silencing (GO:0060147)2.18960089
162regulation of gene silencing by miRNA (GO:0060964)2.18960089
163regulation of short-term neuronal synaptic plasticity (GO:0048172)2.18012588
164axon extension involved in axon guidance (GO:0048846)2.17697267
165neuron projection extension involved in neuron projection guidance (GO:1902284)2.17697267
166central nervous system neuron axonogenesis (GO:0021955)2.17307130
167heterochromatin organization (GO:0070828)2.16688029
168positive regulation of synapse maturation (GO:0090129)2.16533529
169alternative mRNA splicing, via spliceosome (GO:0000380)2.14495265
170non-canonical Wnt signaling pathway (GO:0035567)2.14455074
171RNA stabilization (GO:0043489)2.14359688
172mRNA stabilization (GO:0048255)2.14359688
173dosage compensation (GO:0007549)2.13378339
174protein localization to synapse (GO:0035418)2.13146011
175facial nerve structural organization (GO:0021612)2.12176067
176spliceosomal tri-snRNP complex assembly (GO:0000244)2.11618599
177ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.11279369
178atrial septum morphogenesis (GO:0060413)2.11055465
179negative regulation of DNA repair (GO:0045738)2.10849753
180hippocampus development (GO:0021766)2.09400919

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.67665510
2EZH2_22144423_ChIP-Seq_EOC_Human3.65855641
3TP63_19390658_ChIP-ChIP_HaCaT_Human3.06134910
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.03989464
5STAT6_21828071_ChIP-Seq_BEAS2B_Human3.03574270
6* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.92167267
7* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.76766450
8E2F7_22180533_ChIP-Seq_HELA_Human2.72557473
9* NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.51617194
10DROSHA_22980978_ChIP-Seq_HELA_Human2.51431767
11EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.35045687
12RCOR2_21632747_ChIP-Seq_MESCs_Mouse2.34016733
13EZH2_27304074_Chip-Seq_ESCs_Mouse2.23128990
14* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.21137665
15WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.12125473
16* ZFP281_27345836_Chip-Seq_ESCs_Mouse2.11707304
17RNF2_18974828_ChIP-Seq_MESCs_Mouse2.11554577
18EZH2_18974828_ChIP-Seq_MESCs_Mouse2.11554577
19CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.10755206
20JARID2_20064375_ChIP-Seq_MESCs_Mouse2.09968155
21ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.05277470
22JARID2_20075857_ChIP-Seq_MESCs_Mouse2.04759452
23DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.89841195
24TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.89778346
25THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.87966833
26MYC_22102868_ChIP-Seq_BL_Human1.87933883
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.87636983
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.87329436
29EED_16625203_ChIP-ChIP_MESCs_Mouse1.83047651
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.74175063
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73974863
32* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.72220830
33RING1B_27294783_Chip-Seq_NPCs_Mouse1.71602114
34RNF2_27304074_Chip-Seq_ESCs_Mouse1.68457922
35PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.68121410
36EGR1_19374776_ChIP-ChIP_THP-1_Human1.67876096
37TP53_20018659_ChIP-ChIP_R1E_Mouse1.67857533
38* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.66862712
39* KDM2B_26808549_Chip-Seq_K562_Human1.65140603
40EZH2_27294783_Chip-Seq_ESCs_Mouse1.64587510
41* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.63536776
42OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.58070916
43FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.55364785
44* ISL1_27105846_Chip-Seq_CPCs_Mouse1.54105979
45SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.53883451
46GATA1_26923725_Chip-Seq_HPCs_Mouse1.53235643
47SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.53002976
48RING1B_27294783_Chip-Seq_ESCs_Mouse1.52625678
49SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.47779440
50SOX2_18555785_ChIP-Seq_MESCs_Mouse1.46836907
51GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.45559789
52KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.43825549
53RARB_27405468_Chip-Seq_BRAIN_Mouse1.43059236
54CIITA_25753668_ChIP-Seq_RAJI_Human1.42774946
55SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.42611002
56SUZ12_27294783_Chip-Seq_ESCs_Mouse1.42073332
57* KDM2B_26808549_Chip-Seq_JURKAT_Human1.40327546
58CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.39687038
59* KDM2B_26808549_Chip-Seq_DND41_Human1.39303212
60CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.34908729
61PKCTHETA_26484144_Chip-Seq_BREAST_Human1.33132957
62* SOX2_16153702_ChIP-ChIP_HESCs_Human1.32942056
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.32612267
64CBX2_27304074_Chip-Seq_ESCs_Mouse1.32466804
65SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.31952947
66SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.31915287
67* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.31914197
68E2F4_17652178_ChIP-ChIP_JURKAT_Human1.31230839
69RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.31032244
70* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.30761910
71* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.30527742
72KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.30037664
73NANOG_21062744_ChIP-ChIP_HESCs_Human1.26467017
74DNAJC2_21179169_ChIP-ChIP_NT2_Human1.24624294
75* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.24418358
76LXR_22292898_ChIP-Seq_THP-1_Human1.23610031
77* CREB1_26743006_Chip-Seq_LNCaP_Human1.22284041
78EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.22115525
79XRN2_22483619_ChIP-Seq_HELA_Human1.21847777
80MYC_19079543_ChIP-ChIP_MESCs_Mouse1.19826150
81DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.19685960
82TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17474833
83POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17474833
84MTF2_20144788_ChIP-Seq_MESCs_Mouse1.12916202
85RNF2_27304074_Chip-Seq_NSC_Mouse1.11779129
86HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10994176
87* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.10668624
88AR_21572438_ChIP-Seq_LNCaP_Human1.09610597
89REST_18959480_ChIP-ChIP_MESCs_Mouse1.09183022
90MYC_18555785_ChIP-Seq_MESCs_Mouse1.09096829
91WT1_19549856_ChIP-ChIP_CCG9911_Human1.08576933
92ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.07671462
93ZNF274_21170338_ChIP-Seq_K562_Hela1.06771364
94ESR1_15608294_ChIP-ChIP_MCF-7_Human1.06331501
95* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.06178844
96REST_21632747_ChIP-Seq_MESCs_Mouse1.05729918
97HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.05623056
98ZNF263_19887448_ChIP-Seq_K562_Human1.05277836
99SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.04390050
100POU5F1_16153702_ChIP-ChIP_HESCs_Human1.04258735
101* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.02715150
102* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.02543931
103POU5F1_16518401_ChIP-PET_MESCs_Mouse1.02375129
104SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01100384
105SRY_22984422_ChIP-ChIP_TESTIS_Rat1.00619925
106SALL1_21062744_ChIP-ChIP_HESCs_Human1.00388273
107* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.00120900
108MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.99248412
109KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.97988399
110KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.97988399
111KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.97988399
112* KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.97412161
113* CTCF_27219007_Chip-Seq_Bcells_Human0.95694828
114DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95114241
115GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94873704
116* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.93848757
117* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.93676659
118* CHD1_26751641_Chip-Seq_LNCaP_Human0.93031815
119OCT4_19829295_ChIP-Seq_ESCs_Human0.92731554
120THAP11_20581084_ChIP-Seq_MESCs_Mouse0.92326246
121TCF7_22412390_ChIP-Seq_EML_Mouse0.92184985
122TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91990310
123TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91840762
124AR_19668381_ChIP-Seq_PC3_Human0.91088114
125SMC4_20622854_ChIP-Seq_HELA_Human0.88427139
126SOX3_22085726_ChIP-Seq_NPCs_Mouse0.87825656
127GBX2_23144817_ChIP-Seq_PC3_Human0.85674489
128* DPY_21335234_ChIP-Seq_ESCs_Mouse0.84197143
129P68_20966046_ChIP-Seq_HELA_Human0.83245822
130CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83082176
131* TET1_21490601_ChIP-Seq_MESCs_Mouse0.82901099
132PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.82864994
133* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.82674166
134* SA1_27219007_Chip-Seq_ERYTHROID_Human0.82560158
135SMAD3_21741376_ChIP-Seq_ESCs_Human0.81797079
136* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.81684044
137RUNX1_26923725_Chip-Seq_HPCs_Mouse0.80133920
138* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.76746820
139* KLF4_19829295_ChIP-Seq_ESCs_Human0.76411719
140MYC_27129775_Chip-Seq_CORNEA_Mouse0.75843341
141* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.72864059

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting3.32220058
2MP0010030_abnormal_orbit_morphology3.27084046
3MP0000537_abnormal_urethra_morphology2.71448140
4MP0002653_abnormal_ependyma_morphology2.52509201
5MP0009053_abnormal_anal_canal2.45818786
6MP0008789_abnormal_olfactory_epithelium2.45509828
7MP0002064_seizures2.42453858
8MP0003121_genomic_imprinting2.41283915
9MP0003123_paternal_imprinting2.38579880
10MP0003385_abnormal_body_wall2.35028980
11MP0009745_abnormal_behavioral_response2.24048563
12MP0004859_abnormal_synaptic_plasticity2.24042912
13MP0005394_taste/olfaction_phenotype2.20703050
14MP0005499_abnormal_olfactory_system2.20703050
15MP0003942_abnormal_urinary_system2.14898450
16MP0002272_abnormal_nervous_system2.08346003
17MP0002822_catalepsy2.07304673
18MP0009379_abnormal_foot_pigmentation2.05670062
19MP0000778_abnormal_nervous_system2.04627436
20MP0002572_abnormal_emotion/affect_behav2.04481419
21MP0001486_abnormal_startle_reflex2.01288072
22MP0003119_abnormal_digestive_system1.96180941
23MP0000049_abnormal_middle_ear1.94964042
24MP0003787_abnormal_imprinting1.94647477
25MP0000534_abnormal_ureter_morphology1.79455222
26MP0004885_abnormal_endolymph1.73328398
27* MP0003861_abnormal_nervous_system1.67913879
28MP0002249_abnormal_larynx_morphology1.67423057
29MP0001188_hyperpigmentation1.67343226
30MP0004270_analgesia1.65959487
31MP0008569_lethality_at_weaning1.65747032
32MP0006276_abnormal_autonomic_nervous1.65261746
33MP0002751_abnormal_autonomic_nervous1.64712249
34MP0001970_abnormal_pain_threshold1.63090134
35MP0002184_abnormal_innervation1.63000178
36MP0003880_abnormal_central_pattern1.61584693
37MP0009250_abnormal_appendicular_skeleto1.57225529
38MP0003315_abnormal_perineum_morphology1.56714953
39MP0003890_abnormal_embryonic-extraembry1.55105398
40MP0003755_abnormal_palate_morphology1.53132674
41MP0006292_abnormal_olfactory_placode1.52230216
42MP0003937_abnormal_limbs/digits/tail_de1.51624525
43MP0005623_abnormal_meninges_morphology1.46175024
44MP0009046_muscle_twitch1.44487577
45MP0004858_abnormal_nervous_system1.44179613
46MP0002233_abnormal_nose_morphology1.43235920
47MP0001440_abnormal_grooming_behavior1.40709194
48MP0001529_abnormal_vocalization1.39185342
49MP0003115_abnormal_respiratory_system1.38681445
50MP0003635_abnormal_synaptic_transmissio1.38462830
51MP0002067_abnormal_sensory_capabilities1.38418749
52MP0009672_abnormal_birth_weight1.37628588
53MP0002234_abnormal_pharynx_morphology1.36799213
54* MP0003935_abnormal_craniofacial_develop1.34721234
55MP0000631_abnormal_neuroendocrine_gland1.34399906
56MP0000428_abnormal_craniofacial_morphol1.32697030
57MP0004742_abnormal_vestibular_system1.31301827
58* MP0002116_abnormal_craniofacial_bone1.30692205
59MP0003111_abnormal_nucleus_morphology1.30488389
60MP0002932_abnormal_joint_morphology1.30248073
61MP0001968_abnormal_touch/_nociception1.29887206
62MP0005187_abnormal_penis_morphology1.27373309
63MP0000955_abnormal_spinal_cord1.26580537
64* MP0002084_abnormal_developmental_patter1.26573405
65MP0003329_amyloid_beta_deposits1.26318916
66* MP0002085_abnormal_embryonic_tissue1.26232135
67MP0002066_abnormal_motor_capabilities/c1.22733874
68MP0005248_abnormal_Harderian_gland1.21636691
69MP0003879_abnormal_hair_cell1.20929229
70* MP0002152_abnormal_brain_morphology1.20724751
71MP0009703_decreased_birth_body1.20464858
72MP0002081_perinatal_lethality1.19585051
73MP0001502_abnormal_circadian_rhythm1.18264171
74MP0004811_abnormal_neuron_physiology1.17510115
75MP0002734_abnormal_mechanical_nocicepti1.17447923
76MP0003878_abnormal_ear_physiology1.17129063
77MP0005377_hearing/vestibular/ear_phenot1.17129063
78MP0000516_abnormal_urinary_system1.15831013
79MP0005367_renal/urinary_system_phenotyp1.15831013
80MP0003938_abnormal_ear_development1.15366547
81MP0002638_abnormal_pupillary_reflex1.13985411
82MP0001485_abnormal_pinna_reflex1.13701976
83MP0002063_abnormal_learning/memory/cond1.13662709
84MP0001293_anophthalmia1.11882514
85MP0004133_heterotaxia1.10416946
86MP0001984_abnormal_olfaction1.08297660
87MP0001299_abnormal_eye_distance/1.08130139
88MP0005646_abnormal_pituitary_gland1.07888965
89MP0008877_abnormal_DNA_methylation1.06601790
90MP0004924_abnormal_behavior1.06212358
91MP0005386_behavior/neurological_phenoty1.06212358
92MP0004197_abnormal_fetal_growth/weight/1.06189201
93MP0002557_abnormal_social/conspecific_i1.04945725
94MP0003705_abnormal_hypodermis_morpholog1.04677955
95* MP0002114_abnormal_axial_skeleton1.04007851
96MP0001286_abnormal_eye_development1.03701869
97MP0002697_abnormal_eye_size1.02937966
98MP0000566_synostosis1.02935591
99MP0005409_darkened_coat_color1.02550964
100MP0001849_ear_inflammation0.99947146
101MP0002282_abnormal_trachea_morphology0.99239291
102MP0002882_abnormal_neuron_morphology0.98791349
103MP0002938_white_spotting0.98666467
104MP0005076_abnormal_cell_differentiation0.98012652
105MP0000026_abnormal_inner_ear0.97610173
106* MP0001697_abnormal_embryo_size0.97587540
107MP0002177_abnormal_outer_ear0.97084557
108MP0001963_abnormal_hearing_physiology0.96638706
109MP0001730_embryonic_growth_arrest0.96517755
110MP0000678_abnormal_parathyroid_gland0.96477084
111MP0002160_abnormal_reproductive_system0.96322955
112MP0003077_abnormal_cell_cycle0.95206835
113MP0005423_abnormal_somatic_nervous0.95001997
114MP0002736_abnormal_nociception_after0.93388634
115MP0008932_abnormal_embryonic_tissue0.92255665
116MP0001501_abnormal_sleep_pattern0.92208887
117* MP0002111_abnormal_tail_morphology0.91885997
118MP0004147_increased_porphyrin_level0.91607592
119MP0003136_yellow_coat_color0.91586932
120MP0008007_abnormal_cellular_replicative0.90308079
121* MP0000432_abnormal_head_morphology0.88537255
122* MP0000350_abnormal_cell_proliferation0.87593594
123MP0004142_abnormal_muscle_tone0.87262284
124MP0004957_abnormal_blastocyst_morpholog0.87055887
125MP0001905_abnormal_dopamine_level0.85852604
126MP0001340_abnormal_eyelid_morphology0.85824334
127MP0002733_abnormal_thermal_nociception0.84758855
128MP0003283_abnormal_digestive_organ0.84607576
129MP0001346_abnormal_lacrimal_gland0.84419181
130MP0010094_abnormal_chromosome_stability0.84302245
131MP0003567_abnormal_fetal_cardiomyocyte0.82930831
132MP0002752_abnormal_somatic_nervous0.82706672
133MP0002735_abnormal_chemical_nociception0.82262508
134* MP0001672_abnormal_embryogenesis/_devel0.81460426
135* MP0005380_embryogenesis_phenotype0.81460426
136MP0006072_abnormal_retinal_apoptosis0.81339877
137MP0002109_abnormal_limb_morphology0.80022908
138MP0002069_abnormal_eating/drinking_beha0.79116324
139MP0003634_abnormal_glial_cell0.77857984
140MP0000579_abnormal_nail_morphology0.76968054
141MP0003633_abnormal_nervous_system0.75762676
142MP0003631_nervous_system_phenotype0.73810869
143MP0002082_postnatal_lethality0.72055555
144MP0010770_preweaning_lethality0.72055555
145MP0002229_neurodegeneration0.72001362
146MP0010769_abnormal_survival0.71661488

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)3.96364398
2Epileptic encephalopathy (HP:0200134)3.47173956
3Renal duplication (HP:0000075)3.46764961
4Short 4th metacarpal (HP:0010044)3.46007061
5Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.46007061
6Limb dystonia (HP:0002451)3.04626281
7Progressive cerebellar ataxia (HP:0002073)2.97785424
8Action tremor (HP:0002345)2.94788416
9Febrile seizures (HP:0002373)2.92336356
10Insomnia (HP:0100785)2.90253846
11Abnormality of the 4th metacarpal (HP:0010012)2.89616164
12Annular pancreas (HP:0001734)2.89100280
13Hyperacusis (HP:0010780)2.76021707
14Ankle clonus (HP:0011448)2.74645038
15Septo-optic dysplasia (HP:0100842)2.71943857
16Shallow orbits (HP:0000586)2.69344203
17Supranuclear gaze palsy (HP:0000605)2.67903002
18Asymmetry of the thorax (HP:0001555)2.61497880
19Abnormality of binocular vision (HP:0011514)2.61390490
20Diplopia (HP:0000651)2.61390490
21Partial duplication of thumb phalanx (HP:0009944)2.58590704
22Abnormal eating behavior (HP:0100738)2.54584319
23Torticollis (HP:0000473)2.51918496
24Renovascular hypertension (HP:0100817)2.50260093
25Partial duplication of the phalanx of hand (HP:0009999)2.44638254
26Pointed chin (HP:0000307)2.38133786
27Abnormality of the aortic arch (HP:0012303)2.33057448
28Midline defect of the nose (HP:0004122)2.32854257
29Atonic seizures (HP:0010819)2.32304754
30Increased nuchal translucency (HP:0010880)2.31943811
31Sacral dimple (HP:0000960)2.29158825
32Generalized tonic-clonic seizures (HP:0002069)2.27131771
33Polyphagia (HP:0002591)2.26817052
34Elfin facies (HP:0004428)2.25316833
35Drooling (HP:0002307)2.23400758
36Spastic gait (HP:0002064)2.22591070
37Cutaneous finger syndactyly (HP:0010554)2.21897845
38Visual hallucinations (HP:0002367)2.18917394
39Morphological abnormality of the middle ear (HP:0008609)2.16413671
40Hepatoblastoma (HP:0002884)2.16008467
41Trigonocephaly (HP:0000243)2.15997829
42Abnormality of the lower motor neuron (HP:0002366)2.15375607
43Neurofibrillary tangles (HP:0002185)2.12385085
44Bowel diverticulosis (HP:0005222)2.10278884
45Abnormality of the labia minora (HP:0012880)2.08049411
46Vertebral arch anomaly (HP:0008438)2.07535473
47Oligodactyly (hands) (HP:0001180)2.07117169
48Overriding aorta (HP:0002623)2.06980698
49Focal dystonia (HP:0004373)2.06655843
50Urinary bladder sphincter dysfunction (HP:0002839)2.05967164
51Excessive salivation (HP:0003781)2.05431533
52Aplasia involving bones of the upper limbs (HP:0009823)2.05255198
53Aplasia of the phalanges of the hand (HP:0009802)2.05255198
54Aplasia involving bones of the extremities (HP:0009825)2.05255198
55Aplasia/Hypoplasia of the sternum (HP:0006714)2.05091700
56Aplasia/Hypoplasia of the patella (HP:0006498)2.03466137
57Broad-based gait (HP:0002136)2.03360922
58Shawl scrotum (HP:0000049)2.03171703
59Abnormal hair whorl (HP:0010721)2.01192148
60Cutaneous syndactyly (HP:0012725)2.00695559
61Impaired vibration sensation in the lower limbs (HP:0002166)2.00373352
62Spina bifida occulta (HP:0003298)1.99854546
63Split foot (HP:0001839)1.99072203
64Deviation of the hallux (HP:0010051)1.97864858
65Abnormality of the corticospinal tract (HP:0002492)1.97814369
66Abnormality of the phalanges of the hallux (HP:0010057)1.97059593
67Patellar aplasia (HP:0006443)1.96344110
68Abnormality of the intervertebral disk (HP:0005108)1.95725812
69Broad palm (HP:0001169)1.93100631
70Stereotypic behavior (HP:0000733)1.92367187
71Abnormality of the diencephalon (HP:0010662)1.92070678
72Sleep apnea (HP:0010535)1.90834384
73Hyperthyroidism (HP:0000836)1.89905712
74Flat cornea (HP:0007720)1.89329188
75Broad thumb (HP:0011304)1.88657042
76Obstructive sleep apnea (HP:0002870)1.88355310
77Pseudobulbar signs (HP:0002200)1.87667175
78Hallux valgus (HP:0001822)1.86232219
79Abnormal respiratory motile cilium morphology (HP:0005938)1.86106608
80Abnormal respiratory epithelium morphology (HP:0012253)1.86106608
81Myokymia (HP:0002411)1.85698690
82Oligodactyly (HP:0012165)1.85311496
83Hypoventilation (HP:0002791)1.84969547
84Abnormal number of incisors (HP:0011064)1.84725378
85Peripheral hypomyelination (HP:0007182)1.84113904
86Bronchomalacia (HP:0002780)1.83060055
87Obsessive-compulsive behavior (HP:0000722)1.82970303
88Papilledema (HP:0001085)1.82717666
89Abnormal ciliary motility (HP:0012262)1.82228904
90Anosmia (HP:0000458)1.82049711
91Bicornuate uterus (HP:0000813)1.81809738
92Broad metatarsal (HP:0001783)1.81773216
93Osteomalacia (HP:0002749)1.81097783
94Genetic anticipation (HP:0003743)1.79999299
95Coronal craniosynostosis (HP:0004440)1.79887973
96Rib fusion (HP:0000902)1.79487226
97Broad toe (HP:0001837)1.79293742
98Patellar dislocation (HP:0002999)1.79135337
99Morphological abnormality of the inner ear (HP:0011390)1.79047695
100High anterior hairline (HP:0009890)1.78977631
101Short 5th finger (HP:0009237)1.78846749
102Renal hypoplasia (HP:0000089)1.78834583
103Craniofacial dystonia (HP:0012179)1.78763451
104Depression (HP:0000716)1.78667653
105Shoulder girdle muscle weakness (HP:0003547)1.78564419
106Abnormality of cochlea (HP:0000375)1.77747971
107Failure to thrive in infancy (HP:0001531)1.77026540
108Deep palmar crease (HP:0006191)1.76803205
109Dysmetria (HP:0001310)1.76623755
110Diastasis recti (HP:0001540)1.75468132
111Colon cancer (HP:0003003)1.72711485
112Absent septum pellucidum (HP:0001331)1.72369747
113Broad finger (HP:0001500)1.72184999
114Cortical dysplasia (HP:0002539)1.71493682
115Overgrowth (HP:0001548)1.71227398
116Aqueductal stenosis (HP:0002410)1.71206068
117Autism (HP:0000717)1.71065689
118Abnormality of abdominal situs (HP:0011620)1.70846268
119Abdominal situs inversus (HP:0003363)1.70846268
120Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.70759605
121Absence seizures (HP:0002121)1.70688273
122Truncus arteriosus (HP:0001660)1.69836754
123Abnormal respiratory motile cilium physiology (HP:0012261)1.69814859
124Dialeptic seizures (HP:0011146)1.69123537
125Maternal diabetes (HP:0009800)1.68786986
126Long palpebral fissure (HP:0000637)1.68539571
127Sporadic (HP:0003745)1.68337671
128Cerebral inclusion bodies (HP:0100314)1.68236793
129Atresia of the external auditory canal (HP:0000413)1.67244867
130Broad phalanges of the hand (HP:0009768)1.66795021
131Abnormality of the middle phalanges of the toes (HP:0010183)1.66471582
132Bladder diverticulum (HP:0000015)1.66076259
133Bowel incontinence (HP:0002607)1.65960378
134Protrusio acetabuli (HP:0003179)1.64550552
135Lower limb asymmetry (HP:0100559)1.64376482
136Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.64113900
137Short 1st metacarpal (HP:0010034)1.64113900
138Mutism (HP:0002300)1.63870236
139Agitation (HP:0000713)1.62701505
140Germ cell neoplasia (HP:0100728)1.62611961
141Choanal stenosis (HP:0000452)1.62597984
142Megalencephaly (HP:0001355)1.62539747
143Omphalocele (HP:0001539)1.62024909
144Esophageal atresia (HP:0002032)1.61418378
145Microglossia (HP:0000171)1.61373727
146Epileptiform EEG discharges (HP:0011182)1.60920275
147Overlapping toe (HP:0001845)1.60347632
148Abnormality of the parietal bone (HP:0002696)1.59610702
149Anophthalmia (HP:0000528)1.57530480
150Precocious puberty (HP:0000826)1.56925229
151Generalized hypotonia (HP:0001290)1.56921960
152Amblyopia (HP:0000646)1.56682029
153Bifid tongue (HP:0010297)1.56277342
154Wrist flexion contracture (HP:0001239)1.56047382
155Absent eyebrow (HP:0002223)1.55847555
156Broad distal phalanx of finger (HP:0009836)1.55746830
157Focal seizures (HP:0007359)1.55102400
158Megalocornea (HP:0000485)1.53639977
159Facial hemangioma (HP:0000329)1.53568514
160Turricephaly (HP:0000262)1.53162154
161Chin dimple (HP:0010751)1.53152279
162Vesicoureteral reflux (HP:0000076)1.52094316
163Broad phalanx (HP:0006009)1.51805561
164Radioulnar synostosis (HP:0002974)1.50904617
165Down-sloping shoulders (HP:0200021)1.50246424
166Enlarged penis (HP:0000040)1.50005537
167Hypoplasia of the maxilla (HP:0000327)1.49860232
168Adducted thumb (HP:0001181)1.49628395
169Broad long bones (HP:0005622)1.49338307
170Pelvic girdle muscle weakness (HP:0003749)1.48795231

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK12.82809839
2EEF2K2.54387012
3MAP3K102.54041211
4LATS22.53037992
5EPHB22.41939508
6CDC72.28615508
7MKNK12.00629744
8CDK121.97949031
9NTRK31.96420156
10MINK11.96379974
11TNIK1.93034355
12UHMK11.91895069
13PRKD31.83101752
14MKNK21.82341222
15MAPK131.82095073
16TRIB31.70536155
17DAPK21.65102599
18MAP3K41.61267591
19FGFR21.58607166
20SIK21.54034550
21PKN21.49266804
22SRPK11.49165400
23ERBB31.42945206
24PDGFRA1.41824992
25KSR11.41026480
26PNCK1.35458186
27RPS6KA21.28327220
28ARAF1.28031927
29BRD41.27400450
30NTRK21.19100943
31CAMK1G1.18986298
32MAPK151.17582736
33STK111.17361286
34TLK11.15834682
35CAMK11.12430492
36ICK1.09677905
37DYRK21.09652240
38EPHA41.08659551
39KSR21.08635743
40PLK31.06033522
41ALK1.05336302
42SGK21.04470263
43CAMK1D1.03761570
44CASK1.02287984
45MAP2K40.98611891
46PLK20.97910509
47DMPK0.94314558
48CDK140.93868692
49ERBB20.92734644
50SGK4940.91212917
51SGK2230.91212917
52PAK60.91012727
53CDK180.90606088
54RIPK10.88827896
55LATS10.87880480
56CDK150.87866209
57MAP2K70.87498272
58MAP3K110.86575795
59SGK30.86166329
60FGFR10.86079929
61BRSK10.86032210
62CDK11A0.85877893
63CDK190.84803813
64AURKA0.82616329
65MAP3K90.80949844
66TYRO30.80408709
67RPS6KB20.79979186
68MTOR0.79612165
69TSSK60.79368890
70PTK20.79145073
71NEK10.79133336
72SGK10.76578595
73BRAF0.76047615
74CDK80.75140038
75PTK60.74857829
76LIMK10.74452766
77NEK20.74252959
78FER0.73878665
79PRKCI0.73410077
80DYRK1B0.72411775
81GRK50.72371803
82BUB10.72210970
83CDK20.71562814
84PRPF4B0.71429248
85CSNK1E0.71331386
86DYRK30.70591502
87PASK0.70207158
88TAOK10.69909602
89PAK30.68188932
90CDK10.67520357
91TGFBR10.66910846
92RET0.66504804
93WNK10.64891609
94PRKCZ0.64079055
95PKN10.63767644
96MAPK80.63081357
97DDR20.62524084
98CDK50.62259388
99MAPK90.60666022
100DYRK1A0.60497825
101CHEK10.59744343
102PLK10.59198595
103DAPK10.59037677
104PRKCH0.58671150
105MARK20.58636722
106CDC42BPA0.58537762
107CAMKK10.58403893
108NTRK10.57956712
109PRKCG0.57026465
110PINK10.56755277
111RIPK40.56744058
112WNK30.55833096
113SCYL20.55507626
114CSNK1G20.54829727
115GSK3B0.54391452
116MAPK100.53523809
117RPS6KC10.52720214
118RPS6KL10.52720214
119ROCK10.52630391
120MAP2K20.52119588
121CAMK40.51534387
122ILK0.51349381
123CDK70.51297051
124RPS6KA30.50919914
125CAMK2A0.47501745
126PHKG20.47447410
127PHKG10.47447410
128CDK30.45611240
129SIK10.44636506
130CAMK2B0.43408626
131MAPK120.40049950
132PRKDC0.38162898
133ROCK20.36199647
134TNK20.35355745
135RPS6KA60.34298469
136FYN0.33694394

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052172.45239951
2Hedgehog signaling pathway_Homo sapiens_hsa043402.11489826
3mRNA surveillance pathway_Homo sapiens_hsa030152.10967958
4Endometrial cancer_Homo sapiens_hsa052132.00203925
5Spliceosome_Homo sapiens_hsa030401.95873039
6Hippo signaling pathway_Homo sapiens_hsa043901.95686995
7Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.91537785
8Axon guidance_Homo sapiens_hsa043601.90075158
9Melanogenesis_Homo sapiens_hsa049161.76869763
10Wnt signaling pathway_Homo sapiens_hsa043101.68313455
11Oocyte meiosis_Homo sapiens_hsa041141.68217407
12Thyroid cancer_Homo sapiens_hsa052161.65848037
13Synaptic vesicle cycle_Homo sapiens_hsa047211.65183139
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.64659150
15Dopaminergic synapse_Homo sapiens_hsa047281.62856298
16Glioma_Homo sapiens_hsa052141.60909204
17Colorectal cancer_Homo sapiens_hsa052101.58977276
18Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.57976407
19Olfactory transduction_Homo sapiens_hsa047401.56137954
20Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.56089340
21Long-term potentiation_Homo sapiens_hsa047201.55946374
22Cell cycle_Homo sapiens_hsa041101.53143776
23Chronic myeloid leukemia_Homo sapiens_hsa052201.43338950
24Bladder cancer_Homo sapiens_hsa052191.41187610
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.39311964
26Cardiac muscle contraction_Homo sapiens_hsa042601.37673370
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.34310972
28Gap junction_Homo sapiens_hsa045401.34045242
29Amphetamine addiction_Homo sapiens_hsa050311.32834060
30Non-small cell lung cancer_Homo sapiens_hsa052231.32701569
31Nicotine addiction_Homo sapiens_hsa050331.32184844
32Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.32178746
33Cholinergic synapse_Homo sapiens_hsa047251.30559727
34RNA transport_Homo sapiens_hsa030131.26006734
35ErbB signaling pathway_Homo sapiens_hsa040121.25520155
36Melanoma_Homo sapiens_hsa052181.25147295
37Neurotrophin signaling pathway_Homo sapiens_hsa047221.22983281
38Estrogen signaling pathway_Homo sapiens_hsa049151.22936095
39Adherens junction_Homo sapiens_hsa045201.22389972
40MicroRNAs in cancer_Homo sapiens_hsa052061.20937384
41Notch signaling pathway_Homo sapiens_hsa043301.19083168
42Circadian entrainment_Homo sapiens_hsa047131.18680387
43Insulin secretion_Homo sapiens_hsa049111.15351957
44Thyroid hormone signaling pathway_Homo sapiens_hsa049191.15255041
45Cocaine addiction_Homo sapiens_hsa050301.14222490
46Calcium signaling pathway_Homo sapiens_hsa040201.11974477
47Alcoholism_Homo sapiens_hsa050341.06794445
48Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.05810616
49Long-term depression_Homo sapiens_hsa047301.04311792
50Aldosterone synthesis and secretion_Homo sapiens_hsa049251.03560548
51Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.02897810
52Phospholipase D signaling pathway_Homo sapiens_hsa040721.02185082
53Prostate cancer_Homo sapiens_hsa052151.01783294
54Taste transduction_Homo sapiens_hsa047421.01106966
55Glutamatergic synapse_Homo sapiens_hsa047241.00423472
56GnRH signaling pathway_Homo sapiens_hsa049121.00230441
57TGF-beta signaling pathway_Homo sapiens_hsa043501.00145042
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.97807954
59Tight junction_Homo sapiens_hsa045300.97593319
60Renal cell carcinoma_Homo sapiens_hsa052110.96065015
61Lysine degradation_Homo sapiens_hsa003100.95935789
62Oxytocin signaling pathway_Homo sapiens_hsa049210.95142156
63Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.94946858
64Central carbon metabolism in cancer_Homo sapiens_hsa052300.94930022
65Collecting duct acid secretion_Homo sapiens_hsa049660.94862503
66Proteoglycans in cancer_Homo sapiens_hsa052050.94467139
67mTOR signaling pathway_Homo sapiens_hsa041500.94156230
68Mismatch repair_Homo sapiens_hsa034300.92135771
69Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.92104481
70GABAergic synapse_Homo sapiens_hsa047270.90247678
71Ras signaling pathway_Homo sapiens_hsa040140.89848576
72Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.87662028
73Morphine addiction_Homo sapiens_hsa050320.87593545
74Insulin signaling pathway_Homo sapiens_hsa049100.85888395
75Thyroid hormone synthesis_Homo sapiens_hsa049180.85218632
76HTLV-I infection_Homo sapiens_hsa051660.83195485
77Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.80804652
78Pathways in cancer_Homo sapiens_hsa052000.80759240
79Prolactin signaling pathway_Homo sapiens_hsa049170.80601689
80Prion diseases_Homo sapiens_hsa050200.79768604
81VEGF signaling pathway_Homo sapiens_hsa043700.79467278
82Rap1 signaling pathway_Homo sapiens_hsa040150.79305236
83Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.79088694
84Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78875210
85Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.78774683
86Base excision repair_Homo sapiens_hsa034100.78014815
87DNA replication_Homo sapiens_hsa030300.77374637
88MAPK signaling pathway_Homo sapiens_hsa040100.75598403
89Gastric acid secretion_Homo sapiens_hsa049710.74970607
90Nucleotide excision repair_Homo sapiens_hsa034200.74384832
91Bile secretion_Homo sapiens_hsa049760.72999050
92Phosphatidylinositol signaling system_Homo sapiens_hsa040700.72829856
93FoxO signaling pathway_Homo sapiens_hsa040680.72164649
94Type II diabetes mellitus_Homo sapiens_hsa049300.71743629
95Vascular smooth muscle contraction_Homo sapiens_hsa042700.71148609
96Serotonergic synapse_Homo sapiens_hsa047260.71109690
97Pancreatic secretion_Homo sapiens_hsa049720.69427319
98Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68477617
99cGMP-PKG signaling pathway_Homo sapiens_hsa040220.67975902
100Pancreatic cancer_Homo sapiens_hsa052120.67410816
101Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.65356443
102Dorso-ventral axis formation_Homo sapiens_hsa043200.65261103
103Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64778121
104Phototransduction_Homo sapiens_hsa047440.63435438
105RNA degradation_Homo sapiens_hsa030180.62777291
106Focal adhesion_Homo sapiens_hsa045100.62210364
107Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.60470633
108Ribosome_Homo sapiens_hsa030100.58937843
109cAMP signaling pathway_Homo sapiens_hsa040240.57593957
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.57500526
111Glucagon signaling pathway_Homo sapiens_hsa049220.57261888
112Inositol phosphate metabolism_Homo sapiens_hsa005620.57149118
113Renin secretion_Homo sapiens_hsa049240.56183223
114Acute myeloid leukemia_Homo sapiens_hsa052210.55820940
115Salivary secretion_Homo sapiens_hsa049700.54715023
116Dilated cardiomyopathy_Homo sapiens_hsa054140.54151887
117AMPK signaling pathway_Homo sapiens_hsa041520.53478449
118Choline metabolism in cancer_Homo sapiens_hsa052310.53462218
119Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52230099
120Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51151957
121Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45710957
122Vibrio cholerae infection_Homo sapiens_hsa051100.41281952
123Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40654650
124Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39243164
125Alzheimers disease_Homo sapiens_hsa050100.38867047
126Huntingtons disease_Homo sapiens_hsa050160.36714176
127Ovarian steroidogenesis_Homo sapiens_hsa049130.36445915
128Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.33787635

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