SSBP4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)5.10854666
2motile cilium assembly (GO:0044458)4.87957061
3viral transcription (GO:0019083)4.59398717
4ribosomal small subunit assembly (GO:0000028)4.46460099
5translational termination (GO:0006415)4.27616295
6negative regulation of erythrocyte differentiation (GO:0045647)4.17709669
7DNA deamination (GO:0045006)3.96412058
8translational elongation (GO:0006414)3.94709277
9synaptic vesicle maturation (GO:0016188)3.78762468
10tolerance induction (GO:0002507)3.77293280
11antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.74186830
12antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.74186830
13cilium or flagellum-dependent cell motility (GO:0001539)3.61197094
14antigen processing and presentation via MHC class Ib (GO:0002475)3.60147380
15nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.54006748
16modulation by virus of host process (GO:0019054)3.50686691
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.48731392
18mannose metabolic process (GO:0006013)3.42342640
19signal complex assembly (GO:0007172)3.42167263
20left/right pattern formation (GO:0060972)3.39762474
21peptidyl-arginine omega-N-methylation (GO:0035247)3.39659459
22negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.39450403
23protein targeting to ER (GO:0045047)3.38420445
24viral life cycle (GO:0019058)3.36118540
25cellular protein complex disassembly (GO:0043624)3.32361359
26cotranslational protein targeting to membrane (GO:0006613)3.31888189
27G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.30192178
28negative regulation of RNA splicing (GO:0033119)3.25137790
29regulation of extracellular matrix disassembly (GO:0010715)3.24852970
30maternal placenta development (GO:0001893)3.24684037
31ribosomal small subunit biogenesis (GO:0042274)3.24627414
32translational initiation (GO:0006413)3.23742064
33establishment of protein localization to endoplasmic reticulum (GO:0072599)3.22677890
34regulation of early endosome to late endosome transport (GO:2000641)3.21877976
35negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.21766497
36negative regulation of cell killing (GO:0031342)3.21766497
37regulation of synapse structural plasticity (GO:0051823)3.20396658
38ncRNA 3-end processing (GO:0043628)3.20017372
39regulation of protein heterodimerization activity (GO:0043497)3.18515563
40protein complex disassembly (GO:0043241)3.17969138
41barbed-end actin filament capping (GO:0051016)3.17238295
42apoptotic process involved in morphogenesis (GO:0060561)3.16278422
43mitotic G1 DNA damage checkpoint (GO:0031571)3.14478958
44protein localization to endoplasmic reticulum (GO:0070972)3.12336411
45sodium ion export (GO:0071436)3.11693426
46modulation by symbiont of host cellular process (GO:0044068)3.09910504
47UV protection (GO:0009650)3.09349768
48regulation of mammary gland epithelial cell proliferation (GO:0033599)3.06402314
49DNA unwinding involved in DNA replication (GO:0006268)3.04601687
50locomotory exploration behavior (GO:0035641)3.04347881
51cilium movement (GO:0003341)3.03231739
52peptidyl-lysine dimethylation (GO:0018027)3.03178071
53positive regulation of lamellipodium assembly (GO:0010592)3.02808130
54maturation of SSU-rRNA (GO:0030490)2.99677533
55negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.98361344
56regulation of ARF protein signal transduction (GO:0032012)2.97596058
57cell-cell junction maintenance (GO:0045217)2.95704045
58macromolecular complex disassembly (GO:0032984)2.95692998
59positive regulation of gamma-delta T cell activation (GO:0046645)2.95019084
60peptidyl-arginine methylation (GO:0018216)2.93842818
61peptidyl-arginine N-methylation (GO:0035246)2.93842818
62antigen processing and presentation of endogenous antigen (GO:0019883)2.91997944
63regulation of response to osmotic stress (GO:0047484)2.89587067
64regulation of defense response to virus by virus (GO:0050690)2.89220970
65regulation of ARF GTPase activity (GO:0032312)2.89106000
66positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.88987439
67positive regulation of histone deacetylation (GO:0031065)2.88782046
68activation of MAPKKK activity (GO:0000185)2.86621314
69positive regulation of Rap GTPase activity (GO:0032854)2.85537157
70regulation of translational termination (GO:0006449)2.85134283
71response to muramyl dipeptide (GO:0032495)2.84002553
72Arp2/3 complex-mediated actin nucleation (GO:0034314)2.83319230
73stress fiber assembly (GO:0043149)2.82710716
74negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.82593770
75regulation of gamma-delta T cell differentiation (GO:0045586)2.82236158
76negative regulation of cell size (GO:0045792)2.81768371
77positive regulation of protein dephosphorylation (GO:0035307)2.81740906
78regulation of translational fidelity (GO:0006450)2.81654009
79positive regulation by organism of defense response of other organism involved in symbiotic interact2.81374405
80modulation by symbiont of host immune response (GO:0052553)2.81374405
81positive regulation by symbiont of host defense response (GO:0052509)2.81374405
82modulation by symbiont of host defense response (GO:0052031)2.81374405
83modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.81374405
84modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.81374405
85adenosine receptor signaling pathway (GO:0001973)2.81090933
86T cell apoptotic process (GO:0070231)2.80594868
87positive regulation of protein deacetylation (GO:0090312)2.78337923
88positive regulation of lamellipodium organization (GO:1902745)2.77315278
89response to peptidoglycan (GO:0032494)2.75467770
90deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.75380688
91regulation of erythrocyte differentiation (GO:0045646)2.74696728
92positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.72787335
93protein retention in ER lumen (GO:0006621)2.70536325
94synaptic vesicle exocytosis (GO:0016079)2.70190127
95histone H4-K12 acetylation (GO:0043983)2.69656539
96negative regulation of granulocyte differentiation (GO:0030853)2.69370209
97positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.68958162
98negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.66991927
99semaphorin-plexin signaling pathway (GO:0071526)2.65035471
100positive thymic T cell selection (GO:0045059)2.63061460
101response to parathyroid hormone (GO:0071107)2.62775088
102response to laminar fluid shear stress (GO:0034616)2.61336205
103modulation by virus of host morphology or physiology (GO:0019048)2.58512592
104COPI coating of Golgi vesicle (GO:0048205)2.57243884
105Golgi transport vesicle coating (GO:0048200)2.57243884
106pentose-phosphate shunt (GO:0006098)2.56843449
107DNA strand elongation involved in DNA replication (GO:0006271)2.56095813
108mitotic G1/S transition checkpoint (GO:0044819)2.55875286
109positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.55627842
110dopamine receptor signaling pathway (GO:0007212)2.53826181
111peptidyl-tyrosine autophosphorylation (GO:0038083)2.53426849
112phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.53216665
113synaptic vesicle docking involved in exocytosis (GO:0016081)2.53186009
114regulation of Rap GTPase activity (GO:0032317)2.52490238
115NIK/NF-kappaB signaling (GO:0038061)2.51325343
116negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.50822478
117mature B cell differentiation involved in immune response (GO:0002313)2.50752626
118natural killer cell differentiation (GO:0001779)2.49821210
119negative regulation of mRNA processing (GO:0050686)2.49330502
120mucosal-associated lymphoid tissue development (GO:0048537)2.49023354
121Peyers patch development (GO:0048541)2.49023354
122establishment of apical/basal cell polarity (GO:0035089)2.48508756
123regulation of short-term neuronal synaptic plasticity (GO:0048172)2.48365620
124positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.47588798
125regulation of leukocyte degranulation (GO:0043300)2.47316248
126cytoskeletal anchoring at plasma membrane (GO:0007016)2.46253418
127histone arginine methylation (GO:0034969)2.45041506
128protein insertion into membrane (GO:0051205)2.44740903
129thymic T cell selection (GO:0045061)2.44220155
130protein targeting to membrane (GO:0006612)2.44135200
131negative regulation of phagocytosis (GO:0050765)2.43625563
132regulation of integrin activation (GO:0033623)2.43543326
133intracellular estrogen receptor signaling pathway (GO:0030520)2.43461580
134nuclear-transcribed mRNA catabolic process (GO:0000956)2.43447687
135maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.43400440
136lymphocyte apoptotic process (GO:0070227)2.42083956
137telomere maintenance via semi-conservative replication (GO:0032201)2.41761193
138protein localization to endosome (GO:0036010)2.41296956
1393-UTR-mediated mRNA stabilization (GO:0070935)2.39705928
140positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.39703522
141negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.37565570
142respiratory system process (GO:0003016)2.36791982
143DNA strand elongation (GO:0022616)2.36629847
144regulation of gamma-delta T cell activation (GO:0046643)2.36482291
145positive regulation of synapse maturation (GO:0090129)2.36459484
146glial cell proliferation (GO:0014009)2.36391161
147formation of translation preinitiation complex (GO:0001731)2.36214566
148positive regulation of fibroblast migration (GO:0010763)2.35323850
149megakaryocyte development (GO:0035855)2.35211662
150G1 DNA damage checkpoint (GO:0044783)2.34797593
151activation of JUN kinase activity (GO:0007257)2.34724798
152regulation of extracellular matrix organization (GO:1903053)2.33518174
153lymph vessel development (GO:0001945)2.32927610
154regulation of myeloid leukocyte mediated immunity (GO:0002886)2.32051727
155planar cell polarity pathway involved in neural tube closure (GO:0090179)2.31445539
156pinocytosis (GO:0006907)2.30586044
157positive regulation of blood vessel endothelial cell migration (GO:0043536)2.29611943
158regulation of hydrogen peroxide metabolic process (GO:0010310)2.27949918
159actin filament polymerization (GO:0030041)2.27593250
160negative regulation of leukocyte mediated immunity (GO:0002704)2.27146492
161regulation of protein dephosphorylation (GO:0035304)2.26836631
162detection of bacterium (GO:0016045)2.26478205
163retrograde transport, endosome to Golgi (GO:0042147)2.26286358
164GDP-mannose metabolic process (GO:0019673)2.25055790
165positive regulation of extracellular matrix organization (GO:1903055)2.24970944
166amyloid precursor protein catabolic process (GO:0042987)2.24506118
167lung epithelium development (GO:0060428)2.23794528
168positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.23537640

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* MYC_22102868_ChIP-Seq_BL_Human3.93878427
2E2F7_22180533_ChIP-Seq_HELA_Human3.71919118
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.70232602
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.45124840
5VDR_21846776_ChIP-Seq_THP-1_Human3.17088430
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.81374795
7* LXR_22292898_ChIP-Seq_THP-1_Human2.42889718
8* TCF7_22412390_ChIP-Seq_EML_Mouse2.38244414
9* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.35790142
10* KDM2B_26808549_Chip-Seq_DND41_Human2.32451705
11SCL_19346495_ChIP-Seq_HPC-7_Human2.23233083
12* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.21077789
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.18456397
14RARG_19884340_ChIP-ChIP_MEFs_Mouse2.16012425
15* ELK3_25401928_ChIP-Seq_HUVEC_Human2.10913074
16MYC_18555785_ChIP-Seq_MESCs_Mouse2.03845506
17TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.03326750
18EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.01871511
19* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.92765769
20TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.92610669
21* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.89697218
22RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.89696024
23MAF_26560356_Chip-Seq_TH1_Human1.89098458
24UTX_26944678_Chip-Seq_JUKART_Human1.88666282
25VDR_24763502_ChIP-Seq_THP-1_Human1.84402545
26* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.79192628
27SRY_22984422_ChIP-ChIP_TESTIS_Rat1.78202735
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.77746285
29E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.77073384
30MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.74802805
31CIITA_25753668_ChIP-Seq_RAJI_Human1.72749222
32SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.67806911
33FOXM1_23109430_ChIP-Seq_U2OS_Human1.64510312
34STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.64144208
35XRN2_22483619_ChIP-Seq_HELA_Human1.63622451
36PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.62569785
37* ERG_21242973_ChIP-ChIP_JURKAT_Human1.60689127
38ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.59620212
39CTCF_27219007_Chip-Seq_Bcells_Human1.57917166
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.57706927
41NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.57310245
42IKZF1_21737484_ChIP-ChIP_HCT116_Human1.56681905
43THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.52519237
44TP63_17297297_ChIP-ChIP_HaCaT_Human1.52232650
45* ELF1_20517297_ChIP-Seq_JURKAT_Human1.50211971
46SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.50057229
47SPI1_23127762_ChIP-Seq_K562_Human1.49392814
48* KDM2B_26808549_Chip-Seq_JURKAT_Human1.48785608
49HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.48358500
50MAF_26560356_Chip-Seq_TH2_Human1.48293922
51* P68_20966046_ChIP-Seq_HELA_Human1.46372376
52DNAJC2_21179169_ChIP-ChIP_NT2_Human1.46167097
53ZFP281_27345836_Chip-Seq_ESCs_Mouse1.45188717
54* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.44572951
55* RUNX1_22412390_ChIP-Seq_EML_Mouse1.42858463
56CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.42318534
57DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.39631301
58* RACK7_27058665_Chip-Seq_MCF-7_Human1.39317348
59TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.39039404
60RARB_27405468_Chip-Seq_BRAIN_Mouse1.37536166
61* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.36033879
62CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.35991627
63KDM2B_26808549_Chip-Seq_K562_Human1.35898393
64SA1_27219007_Chip-Seq_ERYTHROID_Human1.33794990
65GATA1_22383799_ChIP-Seq_G1ME_Mouse1.33079410
66CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.30316676
67TET1_21451524_ChIP-Seq_MESCs_Mouse1.30218742
68SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.29496599
69CTCF_27219007_Chip-Seq_ERYTHROID_Human1.29404635
70* BCL6_27268052_Chip-Seq_Bcells_Human1.28371468
71STAT6_21828071_ChIP-Seq_BEAS2B_Human1.27986137
72GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.27745991
73CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.27600128
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26335425
75CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.26199688
76FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.26088170
77PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.25430329
78* CTCF_26484167_Chip-Seq_Bcells_Mouse1.25067078
79TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.24601084
80* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.24079305
81KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.22401904
82DROSHA_22980978_ChIP-Seq_HELA_Human1.20987498
83CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.19674743
84SA1_27219007_Chip-Seq_Bcells_Human1.18737071
85CTCF_21964334_ChIP-Seq_BJAB-B_Human1.18715869
86PU.1_20513432_ChIP-Seq_Bcells_Mouse1.18170112
87MYB_21317192_ChIP-Seq_ERMYB_Mouse1.18125025
88GATA1_19941827_ChIP-Seq_MEL_Mouse1.17834292
89ZNF263_19887448_ChIP-Seq_K562_Human1.16958564
90MYB_26560356_Chip-Seq_TH2_Human1.16391494
91ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.15396922
92BRD4_27068464_Chip-Seq_AML-cells_Mouse1.14360803
93* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.13792618
94* E2F1_20622854_ChIP-Seq_HELA_Human1.13465197
95* TP53_22127205_ChIP-Seq_IMR90_Human1.13410148
96TP63_22573176_ChIP-Seq_HFKS_Human1.13141424
97BCOR_27268052_Chip-Seq_Bcells_Human1.12568930
98* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12355025
99MYB_26560356_Chip-Seq_TH1_Human1.11447803
100CTCF_20526341_ChIP-Seq_ESCs_Human1.09860558
101ESR1_15608294_ChIP-ChIP_MCF-7_Human1.09735414
102THAP11_20581084_ChIP-Seq_MESCs_Mouse1.09503403
103* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09062697
104* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.09003992
105WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.08939658
106NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.08860263
107* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.08180762
108* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.08147784
109SMC4_20622854_ChIP-Seq_HELA_Human1.07678067
110* PHF8_20622854_ChIP-Seq_HELA_Human1.07502605
111* NCOR1_26117541_ChIP-Seq_K562_Human1.06947455
112TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.06583064
113* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.06507891
114CTCF_21964334_Chip-Seq_Bcells_Human1.06495105
115ZFX_18555785_ChIP-Seq_MESCs_Mouse1.05971907
116* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.05061018
117FOXP1_21924763_ChIP-Seq_HESCs_Human1.04124152
118CREB1_26743006_Chip-Seq_LNCaP_Human1.04003060
119RARB_24833708_ChIP-Seq_LIVER_Mouse1.03751325
120* YY1_22570637_ChIP-Seq_MALME-3M_Human1.03520324
121MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.03266533
122KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03091938
123RARA_24833708_ChIP-Seq_LIVER_Mouse1.03082103
124SPI1_23547873_ChIP-Seq_NB4_Human1.02651037
125ESR2_21235772_ChIP-Seq_MCF-7_Human1.02431193
126SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.02413858
127ETS1_21867929_ChIP-Seq_TH2_Mouse1.02055710
128P300_27058665_Chip-Seq_ZR-75-30cells_Human1.01068673
129CTCF_18555785_ChIP-Seq_MESCs_Mouse1.00009471
130TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99916159
131ATF3_27146783_Chip-Seq_COLON_Human0.99598997
132SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.99320496
133VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.99124506
134TET1_21490601_ChIP-Seq_MESCs_Mouse0.98767570
135ETS1_20019798_ChIP-Seq_JURKAT_Human0.98434812
136* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.98319566
137* SMC3_22415368_ChIP-Seq_MEFs_Mouse0.98315882
138RUNX1_27514584_Chip-Seq_MCF-7_Human0.97404998

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.32859719
2MP0003303_peritoneal_inflammation3.06687213
3MP0009379_abnormal_foot_pigmentation2.69160340
4MP0000678_abnormal_parathyroid_gland2.68231449
5MP0002396_abnormal_hematopoietic_system2.54801679
6MP0009278_abnormal_bone_marrow2.49251674
7MP0003300_gastrointestinal_ulcer2.42356269
8MP0005397_hematopoietic_system_phenotyp2.32989732
9MP0001545_abnormal_hematopoietic_system2.32989732
10MP0002249_abnormal_larynx_morphology2.30455666
11MP0008260_abnormal_autophagy2.27587169
12MP0004808_abnormal_hematopoietic_stem2.26266386
13MP0003172_abnormal_lysosome_physiology2.19526842
14MP0002132_abnormal_respiratory_system2.05189834
15MP0003763_abnormal_thymus_physiology2.01559552
16MP0000685_abnormal_immune_system1.97782414
17MP0004858_abnormal_nervous_system1.97431829
18MP0008961_abnormal_basal_metabolism1.96547245
19MP0003635_abnormal_synaptic_transmissio1.92173018
20MP0003279_aneurysm1.89746291
21MP0005623_abnormal_meninges_morphology1.88816344
22MP0002909_abnormal_adrenal_gland1.87891130
23MP0002398_abnormal_bone_marrow1.84055460
24MP0000681_abnormal_thyroid_gland1.81605971
25MP0009333_abnormal_splenocyte_physiolog1.71312705
26MP0005451_abnormal_body_composition1.70372522
27MP0005464_abnormal_platelet_physiology1.70311154
28MP0000703_abnormal_thymus_morphology1.69606413
29MP0003866_abnormal_defecation1.67430530
30MP0002822_catalepsy1.65250851
31MP0005409_darkened_coat_color1.65167089
32MP0003075_altered_response_to1.62760740
33MP0004185_abnormal_adipocyte_glucose1.62186421
34MP0010352_gastrointestinal_tract_polyps1.59553542
35MP0009840_abnormal_foam_cell1.57980945
36MP0003283_abnormal_digestive_organ1.57806596
37MP0003191_abnormal_cellular_cholesterol1.53421815
38MP0000490_abnormal_crypts_of1.52240744
39MP0002722_abnormal_immune_system1.51149016
40MP0003705_abnormal_hypodermis_morpholog1.50379317
41MP0002089_abnormal_postnatal_growth/wei1.48177759
42MP0003123_paternal_imprinting1.43971964
43MP0000689_abnormal_spleen_morphology1.41098450
44MP0002653_abnormal_ependyma_morphology1.40173807
45MP0000465_gastrointestinal_hemorrhage1.40113622
46MP0005174_abnormal_tail_pigmentation1.38260609
47MP0001849_ear_inflammation1.37680789
48MP0005076_abnormal_cell_differentiation1.36410619
49MP0004510_myositis1.35309307
50MP0003111_abnormal_nucleus_morphology1.34557003
51MP0002420_abnormal_adaptive_immunity1.34383240
52MP0000716_abnormal_immune_system1.34140189
53MP0005671_abnormal_response_to1.34072480
54MP0001819_abnormal_immune_cell1.32207738
55MP0002429_abnormal_blood_cell1.29776768
56MP0003436_decreased_susceptibility_to1.28268070
57MP0004957_abnormal_blastocyst_morpholog1.28244418
58MP0002405_respiratory_system_inflammati1.24595023
59MP0002063_abnormal_learning/memory/cond1.24317712
60MP0010307_abnormal_tumor_latency1.23970697
61MP0005000_abnormal_immune_tolerance1.22622296
62MP0001533_abnormal_skeleton_physiology1.22414348
63MP0001873_stomach_inflammation1.21361416
64MP0003693_abnormal_embryo_hatching1.20827666
65MP0003566_abnormal_cell_adhesion1.19685726
66MP0001800_abnormal_humoral_immune1.19283668
67MP0003077_abnormal_cell_cycle1.18710340
68MP0001348_abnormal_lacrimal_gland1.16864173
69MP0002877_abnormal_melanocyte_morpholog1.16328983
70MP0004811_abnormal_neuron_physiology1.16312164
71MP0000858_altered_metastatic_potential1.14189703
72MP0002723_abnormal_immune_serum1.14118560
73MP0005666_abnormal_adipose_tissue1.13907628
74MP0006054_spinal_hemorrhage1.13838866
75MP0005375_adipose_tissue_phenotype1.12896089
76MP0002452_abnormal_antigen_presenting1.12595005
77MP0004947_skin_inflammation1.09408964
78MP0005025_abnormal_response_to1.08679297
79MP0010030_abnormal_orbit_morphology1.08068963
80MP0003329_amyloid_beta_deposits1.05437276
81MP0001663_abnormal_digestive_system1.05423682
82MP0010155_abnormal_intestine_physiology1.05119231
83MP0005167_abnormal_blood-brain_barrier1.04115849
84MP0008569_lethality_at_weaning1.03656876
85MP0008007_abnormal_cellular_replicative1.03121397
86MP0001958_emphysema1.02915855
87MP0005390_skeleton_phenotype1.01983335
88MP0008770_decreased_survivor_rate1.01236942
89MP0001835_abnormal_antigen_presentation1.00754628
90MP0006082_CNS_inflammation1.00240283
91MP0005058_abnormal_lysosome_morphology1.00047925
92MP0002064_seizures0.98866506
93MP0000003_abnormal_adipose_tissue0.98203420
94MP0010234_abnormal_vibrissa_follicle0.97630343
95MP0009745_abnormal_behavioral_response0.96831051
96MP0002998_abnormal_bone_remodeling0.96730865
97MP0000350_abnormal_cell_proliferation0.95462487
98MP0000313_abnormal_cell_death0.93983205
99MP0002019_abnormal_tumor_incidence0.93682143
100MP0005381_digestive/alimentary_phenotyp0.93598443
101MP0002733_abnormal_thermal_nociception0.92212977
102MP0003634_abnormal_glial_cell0.92039309
103MP0001730_embryonic_growth_arrest0.91422738
104MP0005023_abnormal_wound_healing0.87737290
105MP0002166_altered_tumor_susceptibility0.86473547
106MP0002080_prenatal_lethality0.86379496
107MP0001790_abnormal_immune_system0.85238911
108MP0005387_immune_system_phenotype0.85238911
109MP0000358_abnormal_cell_content/0.84744950
110MP0008438_abnormal_cutaneous_collagen0.84477070
111MP0000733_abnormal_muscle_development0.84458263
112MP0005166_decreased_susceptibility_to0.84310296
113MP0005310_abnormal_salivary_gland0.81668432
114MP0003724_increased_susceptibility_to0.80835982
115MP0003453_abnormal_keratinocyte_physiol0.80279912
116MP0003879_abnormal_hair_cell0.78948918
117MP0008874_decreased_physiological_sensi0.77046933
118MP0001502_abnormal_circadian_rhythm0.76863101
119MP0000371_diluted_coat_color0.76857638
120MP0001970_abnormal_pain_threshold0.76631236
121MP0002933_joint_inflammation0.76556398
122MP0005423_abnormal_somatic_nervous0.76484475
123MP0002419_abnormal_innate_immunity0.75445493
124MP0009384_cardiac_valve_regurgitation0.75374088
125MP0001968_abnormal_touch/_nociception0.73996348
126MP0004133_heterotaxia0.73598579
127MP0002572_abnormal_emotion/affect_behav0.72065313
128MP0004130_abnormal_muscle_cell0.71476632
129MP0001845_abnormal_inflammatory_respons0.70319416
130MP0002086_abnormal_extraembryonic_tissu0.70071541
131MP0005508_abnormal_skeleton_morphology0.68489313
132MP0000477_abnormal_intestine_morphology0.67927347
133MP0002148_abnormal_hypersensitivity_rea0.67652532
134MP0010094_abnormal_chromosome_stability0.66714541
135MP0000604_amyloidosis0.66501003
136MP0009785_altered_susceptibility_to0.66468055
137MP0003183_abnormal_peptide_metabolism0.65180965
138MP0005503_abnormal_tendon_morphology0.63350741

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.11888040
2Abnormal respiratory motile cilium morphology (HP:0005938)4.58946184
3Abnormal respiratory epithelium morphology (HP:0012253)4.58946184
4Absent/shortened dynein arms (HP:0200106)4.42923523
5Dynein arm defect of respiratory motile cilia (HP:0012255)4.42923523
6Abnormal respiratory motile cilium physiology (HP:0012261)4.35725167
7Abnormal ciliary motility (HP:0012262)4.19287208
8Hyperacusis (HP:0010780)4.05360843
9Obstructive sleep apnea (HP:0002870)3.79916665
10Annular pancreas (HP:0001734)3.77702024
11Rhinitis (HP:0012384)3.54017321
12Atelectasis (HP:0100750)3.53985090
13Insomnia (HP:0100785)3.29397785
14Cerebral aneurysm (HP:0004944)3.11061519
15Thrombocytosis (HP:0001894)3.05284178
16Broad distal phalanx of finger (HP:0009836)2.99267808
17Abnormality of cells of the erythroid lineage (HP:0012130)2.98566855
18Abnormal number of erythroid precursors (HP:0012131)2.93296481
19Stridor (HP:0010307)2.91260718
20Papilledema (HP:0001085)2.84237935
21Eczematoid dermatitis (HP:0000976)2.82605607
22Hyperthyroidism (HP:0000836)2.75964754
23Pointed chin (HP:0000307)2.75237087
24Elevated erythrocyte sedimentation rate (HP:0003565)2.70934743
25Abnormality of the nasal mucosa (HP:0000433)2.68029513
26Nasal polyposis (HP:0100582)2.64971352
27Visual hallucinations (HP:0002367)2.63974875
28Bronchiectasis (HP:0002110)2.62242279
29Myokymia (HP:0002411)2.53612202
30Large eyes (HP:0001090)2.52925869
31Deep palmar crease (HP:0006191)2.51889911
32Abnormality of the lower motor neuron (HP:0002366)2.50068192
33Truncus arteriosus (HP:0001660)2.48383843
34Chronic obstructive pulmonary disease (HP:0006510)2.47858171
35Obstructive lung disease (HP:0006536)2.47858171
36Polygenic inheritance (HP:0010982)2.47593632
37Recurrent sinusitis (HP:0011108)2.47388354
38Ependymoma (HP:0002888)2.46957821
39Chronic otitis media (HP:0000389)2.43941606
40Recurrent abscess formation (HP:0002722)2.43922656
41Chronic bronchitis (HP:0004469)2.43489902
42Spinal canal stenosis (HP:0003416)2.42433155
43Hypercortisolism (HP:0001578)2.41540071
44Dysostosis multiplex (HP:0000943)2.39832739
45Distal upper limb amyotrophy (HP:0007149)2.39195104
46Upper limb amyotrophy (HP:0009129)2.39195104
47Diminished motivation (HP:0000745)2.37604445
48IgM deficiency (HP:0002850)2.36519310
49Elfin facies (HP:0004428)2.35519978
50Basal cell carcinoma (HP:0002671)2.34850683
51Recurrent otitis media (HP:0000403)2.34008520
52Hand muscle atrophy (HP:0009130)2.28362777
53Acute lymphatic leukemia (HP:0006721)2.26707219
54Protrusio acetabuli (HP:0003179)2.24822060
55Renal duplication (HP:0000075)2.24315722
56Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.23963161
57Recurrent bacterial skin infections (HP:0005406)2.23452719
58Hypertensive crisis (HP:0100735)2.22804171
59Broad palm (HP:0001169)2.19619059
60Petechiae (HP:0000967)2.17848874
61Mucopolysacchariduria (HP:0008155)2.17682645
62Urinary glycosaminoglycan excretion (HP:0003541)2.17682645
63Apathy (HP:0000741)2.16781452
64Increased density of long bones (HP:0006392)2.14401253
65Overriding aorta (HP:0002623)2.14339140
66Vertebral compression fractures (HP:0002953)2.13980465
67Purpura (HP:0000979)2.13192879
68Abnormality of oral frenula (HP:0000190)2.13017280
69Hemiplegia (HP:0002301)2.12752541
70Achilles tendon contracture (HP:0001771)2.11276232
71Fatigue (HP:0012378)2.11272233
72Ankyloglossia (HP:0010296)2.10469438
73Growth hormone excess (HP:0000845)2.09364739
74Distal lower limb muscle weakness (HP:0009053)2.09045701
75Thin bony cortex (HP:0002753)2.08727434
76Amyotrophic lateral sclerosis (HP:0007354)2.07310629
77Supranuclear gaze palsy (HP:0000605)2.07164465
78Reticulocytopenia (HP:0001896)2.06951971
79Impaired smooth pursuit (HP:0007772)2.05558058
80Cellulitis (HP:0100658)2.04657849
81Mitral regurgitation (HP:0001653)2.02857534
82Centrally nucleated skeletal muscle fibers (HP:0003687)2.01921263
83Aplastic anemia (HP:0001915)2.01766672
84Abnormality of mucopolysaccharide metabolism (HP:0011020)2.01699380
85Abnormality of polysaccharide metabolism (HP:0011012)2.01699380
86Abnormality of glycosaminoglycan metabolism (HP:0004371)2.01699380
87Bowel diverticulosis (HP:0005222)2.01589092
88Disproportionate tall stature (HP:0001519)1.99963392
89Prolonged bleeding time (HP:0003010)1.99659899
90Abnormal platelet function (HP:0011869)1.99415388
91Impaired platelet aggregation (HP:0003540)1.99415388
92Depression (HP:0000716)1.99137257
93Thoracic kyphosis (HP:0002942)1.98596462
94Interstitial pulmonary disease (HP:0006530)1.96862420
95Recurrent bronchitis (HP:0002837)1.96665844
96Selective tooth agenesis (HP:0001592)1.96486128
97Male infertility (HP:0003251)1.95171538
98Abnormal delayed hypersensitivity skin test (HP:0002963)1.95133705
99Ankle clonus (HP:0011448)1.93621569
100Radial bowing (HP:0002986)1.93123250
101Chest pain (HP:0100749)1.91742984
102Neuronal loss in central nervous system (HP:0002529)1.91186928
103Turricephaly (HP:0000262)1.88757863
104Astrocytoma (HP:0009592)1.88700179
105Abnormality of the astrocytes (HP:0100707)1.88700179
106Microretrognathia (HP:0000308)1.87984422
107Abnormality of macrophages (HP:0004311)1.87075754
108Increased variability in muscle fiber diameter (HP:0003557)1.86047591
109Bell-shaped thorax (HP:0001591)1.85683211
110Pallor (HP:0000980)1.85463613
111Gastrointestinal inflammation (HP:0004386)1.85405537
112Ocular albinism (HP:0001107)1.84641691
113Increased IgE level (HP:0003212)1.83877716
114Ulnar bowing (HP:0003031)1.83793174
115Increased cerebral lipofuscin (HP:0011813)1.83792504
116Genu recurvatum (HP:0002816)1.82720406
117Lower limb asymmetry (HP:0100559)1.82294961
118Hyperparathyroidism (HP:0000843)1.81725179
119Nuclear cataract (HP:0100018)1.79520872
120Lymphangioma (HP:0100764)1.78809992
121Shallow orbits (HP:0000586)1.78508997
122Renovascular hypertension (HP:0100817)1.78077358
123Joint stiffness (HP:0001387)1.77431731
124Myositis (HP:0100614)1.77302855
125Myopathic facies (HP:0002058)1.76935487
126Poikiloderma (HP:0001029)1.76293248
127Mutism (HP:0002300)1.75218928
128Infertility (HP:0000789)1.75095272
129Cervical subluxation (HP:0003308)1.74881454
130Flat cornea (HP:0007720)1.74492502
131Panhypogammaglobulinemia (HP:0003139)1.73694869
132Aplasia/Hypoplasia of the sacrum (HP:0008517)1.73518524
133Increased neuronal autofluorescent lipopigment (HP:0002074)1.73486207
134Mediastinal lymphadenopathy (HP:0100721)1.72571755
135Abnormality of liposaccharide metabolism (HP:0010968)1.71256838
136Abnormality of glycosphingolipid metabolism (HP:0004343)1.71256838
137Abnormality of glycolipid metabolism (HP:0010969)1.71256838
138Enlarged penis (HP:0000040)1.70955669
139Bulbar palsy (HP:0001283)1.70783508
140Premature rupture of membranes (HP:0001788)1.70591784
141Chronic sinusitis (HP:0011109)1.69741345
142Loss of speech (HP:0002371)1.69469755
143Easy fatigability (HP:0003388)1.69264857
144Striae distensae (HP:0001065)1.68500483
145Angiofibromas (HP:0010615)1.68263331
146Adenoma sebaceum (HP:0009720)1.68263331
147Abnormality of the thoracic spine (HP:0100711)1.67817861
148Neoplasm of the heart (HP:0100544)1.67801408
149Distal lower limb amyotrophy (HP:0008944)1.67733390
150Abnormality of the motor neurons (HP:0002450)1.66722755
151Abnormal neuron morphology (HP:0012757)1.66722755
152Stereotypic behavior (HP:0000733)1.66546727
153Hemorrhage of the eye (HP:0011885)1.66535668
154Iris hypopigmentation (HP:0007730)1.66533755
155Colitis (HP:0002583)1.66321021
156Rectal prolapse (HP:0002035)1.65536094
157Broad face (HP:0000283)1.64917666
158Bowel incontinence (HP:0002607)1.64591576
159Premature skin wrinkling (HP:0100678)1.64005926
160Gingivitis (HP:0000230)1.63890161
161Bicuspid aortic valve (HP:0001647)1.63732293
162Emphysema (HP:0002097)1.63583949
163Abnormality of the Achilles tendon (HP:0005109)1.62956533
164Increased nuchal translucency (HP:0010880)1.62504014
165Resting tremor (HP:0002322)1.62058293
166Flat acetabular roof (HP:0003180)1.61870477
167Rapidly progressive (HP:0003678)1.61805263
168Atrophy/Degeneration involving motor neurons (HP:0007373)1.61074886
169Short nail (HP:0001799)1.60972464

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.11202538
2EEF2K3.75275929
3PKN23.48709707
4SMG13.29398296
5PRPF4B3.02270792
6MAP4K12.88393811
7SCYL22.53458477
8SIK12.39168146
9MAPK152.36301161
10MAP3K102.20373197
11ERN11.97713703
12CAMKK11.94110723
13RIPK41.82770152
14TAOK11.76055004
15FES1.70389523
16SIK21.65448757
17TESK21.65037557
18MAP3K91.64171117
19DAPK11.61892949
20KDR1.57145706
21IRAK31.53890709
22LRRK21.51098083
23TAOK21.47993622
24MAP3K111.47693341
25ZAP701.46518480
26KSR21.45898604
27CAMKK21.41809508
28EPHA41.38520313
29ALK1.36052142
30NTRK31.32387768
31PRKD31.28946427
32NME21.27931695
33PAK41.22970131
34MAP3K131.22158079
35RIPK11.18540577
36CDK191.17722099
37FLT31.17323626
38MATK1.17314184
39TYRO31.16817749
40ICK1.15019389
41GRK61.09534688
42DAPK21.07662596
43PTK61.06193052
44MAP3K31.04197960
45NEK21.03882094
46RAF11.03721257
47KIT1.03196160
48PDPK11.02610364
49PAK61.01947035
50EPHA21.01875151
51UHMK11.01722367
52BTK1.01248227
53MAP2K21.00731787
54PDGFRA0.98497200
55RPS6KC10.98288597
56RPS6KL10.98288597
57PIM20.96624994
58MAPK120.95866700
59CSK0.93501484
60DAPK30.93087733
61MAPKAPK30.92001632
62TTN0.90596624
63NTRK20.90331751
64CDC42BPA0.88861621
65EPHB10.88598546
66MAP3K10.87576031
67TNK20.87116594
68HCK0.86048211
69NEK10.84771822
70FGFR40.81433945
71SYK0.81348697
72CAMK10.81213910
73TESK10.81008655
74BMX0.80944535
75JAK30.80666129
76NTRK10.76070058
77RPS6KA60.75703798
78HIPK20.75260052
79ILK0.73763569
80RPS6KB20.73376150
81MINK10.73366005
82MARK20.71980626
83DDR20.71789861
84MAP3K70.70561868
85BLK0.70534378
86BRSK10.70023321
87BRAF0.69615771
88CSF1R0.68934285
89IRAK40.68423375
90ABL20.67826249
91MAP3K80.66411490
92PRKCH0.65955617
93MTOR0.65718835
94CDK120.65397651
95RET0.64589136
96PASK0.64093582
97CAMK40.63809529
98TBK10.63428517
99PAK20.62642201
100CDK40.62620940
101ARAF0.62053371
102IRAK20.61278551
103MAP3K60.59958233
104CDK50.59394677
105WEE10.58903613
106TYK20.58301871
107PRKD20.58148337
108CDC70.56880251
109MAPK110.54858617
110MAP2K30.53297754
111RPS6KA20.53263000
112CAMK1D0.52206217
113RPS6KA40.51785749
114CDK70.49911773
115STK380.49441961
116LCK0.49124768
117CDK11A0.48903964
118PRKG20.48160096
119TGFBR20.48008872
120PDK10.45741346
121PTK20.45692292
122KSR10.45361208
123MAPK40.45345815
124TNIK0.44726029
125RPS6KA10.44070923
126CDK150.43821931
127DYRK1B0.42993306
128BUB10.42890748
129STK100.40961504
130JAK20.40283941
131DYRK30.40137182
132MAPK70.39684838
133MAP2K60.38421812
134AURKA0.37634106
135PAK10.35287760
136STK110.34794374
137DMPK0.34598603

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030302.12906217
2Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.10539954
3Ribosome_Homo sapiens_hsa030102.00295210
4Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.88249686
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.61349215
6Chronic myeloid leukemia_Homo sapiens_hsa052201.52775330
7VEGF signaling pathway_Homo sapiens_hsa043701.46074024
8Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.40129158
9Acute myeloid leukemia_Homo sapiens_hsa052211.37653346
10Neurotrophin signaling pathway_Homo sapiens_hsa047221.37295391
11B cell receptor signaling pathway_Homo sapiens_hsa046621.36807723
12Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.36763655
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.35272300
14Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.33285837
15Olfactory transduction_Homo sapiens_hsa047401.32602406
16Mismatch repair_Homo sapiens_hsa034301.30285879
17Long-term potentiation_Homo sapiens_hsa047201.29900732
18Non-small cell lung cancer_Homo sapiens_hsa052231.29682698
19Thyroid cancer_Homo sapiens_hsa052161.23111009
20Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.22845442
21Glioma_Homo sapiens_hsa052141.22524135
22Primary immunodeficiency_Homo sapiens_hsa053401.19347888
23Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.18279061
24Spliceosome_Homo sapiens_hsa030401.17029382
25Colorectal cancer_Homo sapiens_hsa052101.16209568
26Synaptic vesicle cycle_Homo sapiens_hsa047211.16107079
27N-Glycan biosynthesis_Homo sapiens_hsa005101.15725769
28Sulfur relay system_Homo sapiens_hsa041221.14727829
29Toll-like receptor signaling pathway_Homo sapiens_hsa046201.12936426
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.09657953
31Base excision repair_Homo sapiens_hsa034101.07853383
32Glycosaminoglycan degradation_Homo sapiens_hsa005311.07610921
33T cell receptor signaling pathway_Homo sapiens_hsa046601.06735726
34Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.06087737
35mTOR signaling pathway_Homo sapiens_hsa041501.04917470
36Estrogen signaling pathway_Homo sapiens_hsa049151.03495485
37Shigellosis_Homo sapiens_hsa051311.03449247
38Bladder cancer_Homo sapiens_hsa052191.03070921
39Choline metabolism in cancer_Homo sapiens_hsa052311.03032388
40Central carbon metabolism in cancer_Homo sapiens_hsa052301.01546587
41Circadian entrainment_Homo sapiens_hsa047131.01440550
42Osteoclast differentiation_Homo sapiens_hsa043801.01247792
43Pentose phosphate pathway_Homo sapiens_hsa000300.98078762
44Leishmaniasis_Homo sapiens_hsa051400.97333588
45Platelet activation_Homo sapiens_hsa046110.96968506
46Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.94868576
47Oxytocin signaling pathway_Homo sapiens_hsa049210.93476337
48Antigen processing and presentation_Homo sapiens_hsa046120.92688884
49Gap junction_Homo sapiens_hsa045400.92571447
50Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.91349422
51GnRH signaling pathway_Homo sapiens_hsa049120.90630798
52Hepatitis C_Homo sapiens_hsa051600.89452764
53Gastric acid secretion_Homo sapiens_hsa049710.88902853
54Hepatitis B_Homo sapiens_hsa051610.88825093
55Dopaminergic synapse_Homo sapiens_hsa047280.88707172
56Thyroid hormone signaling pathway_Homo sapiens_hsa049190.88569319
57Endometrial cancer_Homo sapiens_hsa052130.85565911
58Vibrio cholerae infection_Homo sapiens_hsa051100.85513518
59Other glycan degradation_Homo sapiens_hsa005110.85106396
60Chemokine signaling pathway_Homo sapiens_hsa040620.84872010
61Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.84744473
62Cholinergic synapse_Homo sapiens_hsa047250.84143185
63HTLV-I infection_Homo sapiens_hsa051660.83788594
64Amphetamine addiction_Homo sapiens_hsa050310.83558824
65Fructose and mannose metabolism_Homo sapiens_hsa000510.83000020
66Notch signaling pathway_Homo sapiens_hsa043300.82947918
67AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82820211
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.82223838
69Cocaine addiction_Homo sapiens_hsa050300.81858595
70Morphine addiction_Homo sapiens_hsa050320.81773560
71RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.80095353
72Pancreatic cancer_Homo sapiens_hsa052120.79778830
73Prolactin signaling pathway_Homo sapiens_hsa049170.79743768
74Insulin secretion_Homo sapiens_hsa049110.79437411
75Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78716493
76Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76636178
77Amoebiasis_Homo sapiens_hsa051460.76317555
78Alcoholism_Homo sapiens_hsa050340.75759752
79Endocytosis_Homo sapiens_hsa041440.75176900
80Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.74608736
81Glutamatergic synapse_Homo sapiens_hsa047240.74503266
82GABAergic synapse_Homo sapiens_hsa047270.73765882
83HIF-1 signaling pathway_Homo sapiens_hsa040660.73447422
84Rap1 signaling pathway_Homo sapiens_hsa040150.72075658
85Salivary secretion_Homo sapiens_hsa049700.71761542
86Apoptosis_Homo sapiens_hsa042100.70551312
87TNF signaling pathway_Homo sapiens_hsa046680.70331589
88Inositol phosphate metabolism_Homo sapiens_hsa005620.70251062
89Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.69743788
90ErbB signaling pathway_Homo sapiens_hsa040120.69516830
91Phenylalanine metabolism_Homo sapiens_hsa003600.69440143
92Galactose metabolism_Homo sapiens_hsa000520.69128981
93Melanogenesis_Homo sapiens_hsa049160.68707492
94Oocyte meiosis_Homo sapiens_hsa041140.68298639
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.68212673
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.67647530
97Lysosome_Homo sapiens_hsa041420.66156062
98Viral myocarditis_Homo sapiens_hsa054160.64882869
99Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.64309523
100Prion diseases_Homo sapiens_hsa050200.64180464
101RNA transport_Homo sapiens_hsa030130.63444510
102Type II diabetes mellitus_Homo sapiens_hsa049300.63282356
103Phagosome_Homo sapiens_hsa041450.62751802
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.62076272
105Cyanoamino acid metabolism_Homo sapiens_hsa004600.61476385
106Measles_Homo sapiens_hsa051620.61447368
107Tuberculosis_Homo sapiens_hsa051520.59694828
108Insulin signaling pathway_Homo sapiens_hsa049100.59316280
109MAPK signaling pathway_Homo sapiens_hsa040100.58566164
110Leukocyte transendothelial migration_Homo sapiens_hsa046700.58344255
111Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58327908
112Toxoplasmosis_Homo sapiens_hsa051450.58300614
113Influenza A_Homo sapiens_hsa051640.57764520
114Axon guidance_Homo sapiens_hsa043600.57727413
115Renal cell carcinoma_Homo sapiens_hsa052110.56135616
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56099869
117Viral carcinogenesis_Homo sapiens_hsa052030.55917215
118Salmonella infection_Homo sapiens_hsa051320.55776844
119Adipocytokine signaling pathway_Homo sapiens_hsa049200.55693841
120cAMP signaling pathway_Homo sapiens_hsa040240.54981940
121Proteoglycans in cancer_Homo sapiens_hsa052050.54852496
122Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54835509
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.54688238
124Cell cycle_Homo sapiens_hsa041100.53202755
125Herpes simplex infection_Homo sapiens_hsa051680.51856861
126Collecting duct acid secretion_Homo sapiens_hsa049660.51329225
127Focal adhesion_Homo sapiens_hsa045100.50373795
128Allograft rejection_Homo sapiens_hsa053300.49379264
129Pertussis_Homo sapiens_hsa051330.49111760
130Ras signaling pathway_Homo sapiens_hsa040140.47208549

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