SSNA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.49513405
2ribosomal small subunit biogenesis (GO:0042274)5.23475350
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.12552240
4proteasome assembly (GO:0043248)5.09622858
5viral transcription (GO:0019083)5.00130136
6DNA deamination (GO:0045006)4.98774772
7energy coupled proton transport, down electrochemical gradient (GO:0015985)4.86301126
8ATP synthesis coupled proton transport (GO:0015986)4.86301126
9translational termination (GO:0006415)4.83517275
10protein maturation by protein folding (GO:0022417)4.69443104
11negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.63511256
12chaperone-mediated protein transport (GO:0072321)4.57100364
13cotranslational protein targeting to membrane (GO:0006613)4.56278834
14SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.53422132
15protein targeting to ER (GO:0045047)4.47882946
16maturation of SSU-rRNA (GO:0030490)4.38516949
17protein neddylation (GO:0045116)4.29802064
18protein localization to endoplasmic reticulum (GO:0070972)4.29509436
19establishment of protein localization to endoplasmic reticulum (GO:0072599)4.26544729
20negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.25660881
21translational elongation (GO:0006414)4.18977405
22termination of RNA polymerase III transcription (GO:0006386)4.18864877
23transcription elongation from RNA polymerase III promoter (GO:0006385)4.18864877
24mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.04655383
25GDP-mannose metabolic process (GO:0019673)4.04490274
26negative regulation of ligase activity (GO:0051352)4.01308090
27negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.01308090
28pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.97597867
297-methylguanosine mRNA capping (GO:0006370)3.97312073
30mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.95099396
31mitochondrial respiratory chain complex I assembly (GO:0032981)3.95099396
32NADH dehydrogenase complex assembly (GO:0010257)3.95099396
337-methylguanosine RNA capping (GO:0009452)3.91954596
34RNA capping (GO:0036260)3.91954596
35viral life cycle (GO:0019058)3.91153212
36cellular protein complex disassembly (GO:0043624)3.90540990
37positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.90224234
38deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.87944758
39L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.85464452
40regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.85399648
41DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.84213580
42protein complex biogenesis (GO:0070271)3.83900135
43telomere maintenance via semi-conservative replication (GO:0032201)3.83806802
44regulation of cellular amino acid metabolic process (GO:0006521)3.81798331
45signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.77521463
46intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.77521463
47anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.75943796
48translational initiation (GO:0006413)3.75579548
49antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.75271404
50signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.74539572
51signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.74539572
52signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.74539572
53establishment of protein localization to mitochondrial membrane (GO:0090151)3.70596541
54translation (GO:0006412)3.69918623
55ribosomal large subunit biogenesis (GO:0042273)3.69821533
56respiratory electron transport chain (GO:0022904)3.67789524
57DNA strand elongation involved in DNA replication (GO:0006271)3.66882256
58nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.64112764
59signal transduction involved in DNA integrity checkpoint (GO:0072401)3.61017645
60signal transduction involved in DNA damage checkpoint (GO:0072422)3.61017645
61pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.60432297
62electron transport chain (GO:0022900)3.59636541
63nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.59359295
64nucleobase-containing small molecule interconversion (GO:0015949)3.58031571
65signal transduction involved in cell cycle checkpoint (GO:0072395)3.57465075
66DNA strand elongation (GO:0022616)3.56657217
67mitochondrial respiratory chain complex assembly (GO:0033108)3.56029503
68exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.54688554
69establishment of integrated proviral latency (GO:0075713)3.52881380
70antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.49313336
71GTP biosynthetic process (GO:0006183)3.45964149
722-deoxyribonucleotide biosynthetic process (GO:0009265)3.43750923
73deoxyribose phosphate biosynthetic process (GO:0046385)3.43750923
74respiratory chain complex IV assembly (GO:0008535)3.40685696
75protein targeting to mitochondrion (GO:0006626)3.40525563
76pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.37049265
77transcription-coupled nucleotide-excision repair (GO:0006283)3.36362240
78peptidyl-arginine omega-N-methylation (GO:0035247)3.34551088
79deoxyribonucleotide catabolic process (GO:0009264)3.33444431
80telomere maintenance via recombination (GO:0000722)3.32527840
81protein complex disassembly (GO:0043241)3.31925554
82positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.29826252
83cullin deneddylation (GO:0010388)3.28508017
84ribonucleoprotein complex biogenesis (GO:0022613)3.28328492
85establishment of protein localization to mitochondrion (GO:0072655)3.27799095
86protein deneddylation (GO:0000338)3.25587841
87positive regulation of ligase activity (GO:0051351)3.24198719
88pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.23993121
89deoxyribose phosphate catabolic process (GO:0046386)3.22673625
90cellular component biogenesis (GO:0044085)3.22321815
91negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.22041789
92CENP-A containing nucleosome assembly (GO:0034080)3.20590230
93establishment of viral latency (GO:0019043)3.17539275
94pyrimidine nucleotide catabolic process (GO:0006244)3.16521568
95macromolecular complex disassembly (GO:0032984)3.14638648
96proline biosynthetic process (GO:0006561)3.14054776
97central nervous system myelination (GO:0022010)3.12894588
98axon ensheathment in central nervous system (GO:0032291)3.12894588
99pentose metabolic process (GO:0019321)3.12869291
100rRNA processing (GO:0006364)3.10554414
101purine deoxyribonucleotide catabolic process (GO:0009155)3.09923331
102pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.09833380
103oxidative phosphorylation (GO:0006119)3.09787861
104regulation of mitochondrial translation (GO:0070129)3.09374536
105guanosine-containing compound biosynthetic process (GO:1901070)3.08076209
106CTP metabolic process (GO:0046036)3.06353154
107CTP biosynthetic process (GO:0006241)3.06353154
108pseudouridine synthesis (GO:0001522)3.05908701
109nucleotide salvage (GO:0043173)3.05459160
110transcription elongation from RNA polymerase I promoter (GO:0006362)3.03196466
111UTP biosynthetic process (GO:0006228)3.03168045
112metallo-sulfur cluster assembly (GO:0031163)3.02692806
113iron-sulfur cluster assembly (GO:0016226)3.02692806
114spliceosomal snRNP assembly (GO:0000387)3.02410995
115DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.02281239
116base-excision repair, AP site formation (GO:0006285)3.01839240
117regulation of ubiquitin-protein transferase activity (GO:0051438)3.01710998
118peptidyl-histidine modification (GO:0018202)3.01397945
119nuclear envelope reassembly (GO:0031468)2.99095323
120mitotic nuclear envelope reassembly (GO:0007084)2.99095323
121formation of translation preinitiation complex (GO:0001731)2.98664045
122regulation of ligase activity (GO:0051340)2.98259095
123UTP metabolic process (GO:0046051)2.97924151
124deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.96995163
125regulation of mammary gland epithelial cell proliferation (GO:0033599)2.96771535
126protein localization to mitochondrion (GO:0070585)2.96689202
127chromatin remodeling at centromere (GO:0031055)2.96266318
128pentose-phosphate shunt (GO:0006098)2.96097660
129protein targeting to membrane (GO:0006612)2.95766808
130DNA replication initiation (GO:0006270)2.95734409
131histone arginine methylation (GO:0034969)2.91749343
132purine nucleotide salvage (GO:0032261)2.91179705
133rRNA modification (GO:0000154)2.90983785
1342-deoxyribonucleotide metabolic process (GO:0009394)2.86261716
135pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.82177103
136ribosome biogenesis (GO:0042254)2.76299545

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.82007500
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.78527213
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.41964844
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.09249405
5E2F7_22180533_ChIP-Seq_HELA_Human4.05429688
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.02645727
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.89747069
8MYC_18555785_ChIP-Seq_MESCs_Mouse3.71934006
9* ETS1_20019798_ChIP-Seq_JURKAT_Human3.62519312
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.54493389
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.54377425
12E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.50289593
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.49015598
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.37840574
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.12536740
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.07567175
17* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.91239900
18VDR_23849224_ChIP-Seq_CD4+_Human2.81596596
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.74883238
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.49682400
21SRF_21415370_ChIP-Seq_HL-1_Mouse2.40803436
22THAP11_20581084_ChIP-Seq_MESCs_Mouse2.40162818
23DCP1A_22483619_ChIP-Seq_HELA_Human2.39909192
24* XRN2_22483619_ChIP-Seq_HELA_Human2.38774012
25E2F4_17652178_ChIP-ChIP_JURKAT_Human2.37996477
26VDR_21846776_ChIP-Seq_THP-1_Human2.36343460
27MYC_19079543_ChIP-ChIP_MESCs_Mouse2.33113836
28FOXP3_21729870_ChIP-Seq_TREG_Human2.23201313
29FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.21626646
30* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.13084249
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.10585496
32PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.09896201
33ELK1_19687146_ChIP-ChIP_HELA_Human2.09524183
34* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.04151926
35YY1_21170310_ChIP-Seq_MESCs_Mouse2.02357505
36HOXB4_20404135_ChIP-ChIP_EML_Mouse1.99729095
37TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.97787589
38GABP_19822575_ChIP-Seq_HepG2_Human1.96042552
39TTF2_22483619_ChIP-Seq_HELA_Human1.94905527
40PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.94744003
41HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.93044093
42* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.90570429
43MYC_22102868_ChIP-Seq_BL_Human1.87781090
44FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.86631443
45* LXR_22292898_ChIP-Seq_THP-1_Human1.79608987
46CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.79357075
47TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.76278292
48MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.73517263
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.72213476
50* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.72006790
51NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.68511934
52ERG_20887958_ChIP-Seq_HPC-7_Mouse1.66712018
53* TET1_21451524_ChIP-Seq_MESCs_Mouse1.64546707
54MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.64439026
55SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.58822019
56ELK3_25401928_ChIP-Seq_HUVEC_Human1.56901117
57ZNF263_19887448_ChIP-Seq_K562_Human1.48644110
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.45165536
59PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43550141
60P68_20966046_ChIP-Seq_HELA_Human1.41560187
61YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.38675585
62ELF1_20517297_ChIP-Seq_JURKAT_Human1.36986490
63ELK1_22589737_ChIP-Seq_MCF10A_Human1.34858433
64POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31343960
65RACK7_27058665_Chip-Seq_MCF-7_Human1.30159669
66SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29402596
67RARG_19884340_ChIP-ChIP_MEFs_Mouse1.26614823
68MYCN_18555785_ChIP-Seq_MESCs_Mouse1.25462777
69* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.25054254
70BCL6_27268052_Chip-Seq_Bcells_Human1.24084424
71IRF1_19129219_ChIP-ChIP_H3396_Human1.24005209
72* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.21890302
73MAF_26560356_Chip-Seq_TH2_Human1.21393989
74IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.21145323
75CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.20261679
76CIITA_25753668_ChIP-Seq_RAJI_Human1.19762405
77CTCF_26484167_Chip-Seq_Bcells_Mouse1.19490251
78CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.19420607
79THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.18858987
80STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18700912
81ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.17693705
82KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.17072058
83SPI1_23547873_ChIP-Seq_NB4_Human1.17061124
84MYC_18940864_ChIP-ChIP_HL60_Human1.16849795
85* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.15902882
86SA1_27219007_Chip-Seq_ERYTHROID_Human1.15494713
87CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.14684153
88FOXM1_23109430_ChIP-Seq_U2OS_Human1.14355626
89BCOR_27268052_Chip-Seq_Bcells_Human1.14059525
90* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.13520252
91* FOXP1_21924763_ChIP-Seq_HESCs_Human1.12533795
92ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.12274509
93NANOG_18555785_ChIP-Seq_MESCs_Mouse1.11228524
94CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.07990436
95ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.07552346
96VDR_24763502_ChIP-Seq_THP-1_Human1.06063166
97SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.06012875
98MAF_26560356_Chip-Seq_TH1_Human1.05401463
99UTX_26944678_Chip-Seq_JUKART_Human1.05089797
100BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.05017533
101YY1_22570637_ChIP-Seq_MALME-3M_Human1.04144266
102CTCF_27219007_Chip-Seq_ERYTHROID_Human1.04108366
103CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.02825101
104* CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.02209182
105CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01184126
106NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.00251001
107E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99537748
108PADI4_21655091_ChIP-ChIP_MCF-7_Human0.98659055
109GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97246642
110AR_21909140_ChIP-Seq_LNCAP_Human0.96959261
111CTCF_18555785_ChIP-Seq_MESCs_Mouse0.96539576
112KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93692400
113FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93569541
114POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.92669003
115KDM5A_27292631_Chip-Seq_BREAST_Human0.91515923
116BP1_19119308_ChIP-ChIP_Hs578T_Human0.90146524
117LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.89407033
118E2F1_21310950_ChIP-Seq_MCF-7_Human0.87141848
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.86043848
120RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.84671027
121STAT4_19710469_ChIP-ChIP_TH1__Mouse0.83470808
122HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.81620505
123SOX17_20123909_ChIP-Seq_XEN_Mouse0.81332560
124IRF8_21731497_ChIP-ChIP_J774_Mouse0.80551936
125EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.79393934
126NOTCH1_21737748_ChIP-Seq_TLL_Human0.77152090
127PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.76934125
128MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.76818707
129MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.76536441
130SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.72089191
131TFEB_21752829_ChIP-Seq_HELA_Human0.70103012
132GATA1_22383799_ChIP-Seq_G1ME_Mouse0.70034649
133RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.69925325
134SRY_22984422_ChIP-ChIP_TESTIS_Rat0.68891734
135PU.1_20513432_ChIP-Seq_Bcells_Mouse0.67510702
136SOX2_18555785_ChIP-Seq_MESCs_Mouse0.66566043
137* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.65192682
138TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.64666859
139ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.63319732

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation3.50640983
2MP0005058_abnormal_lysosome_morphology3.24146906
3MP0001529_abnormal_vocalization3.17765711
4MP0003693_abnormal_embryo_hatching3.14289766
5MP0008057_abnormal_DNA_replication3.03827247
6MP0004147_increased_porphyrin_level2.88838892
7MP0004957_abnormal_blastocyst_morpholog2.66137366
8MP0001905_abnormal_dopamine_level2.43666153
9MP0009840_abnormal_foam_cell2.38395088
10MP0003880_abnormal_central_pattern2.35864163
11MP0004185_abnormal_adipocyte_glucose2.35744649
12MP0003191_abnormal_cellular_cholesterol2.34968165
13MP0010094_abnormal_chromosome_stability2.33442150
14MP0003077_abnormal_cell_cycle2.27650662
15MP0008058_abnormal_DNA_repair2.26227020
16MP0003136_yellow_coat_color2.13505314
17MP0003111_abnormal_nucleus_morphology2.08998109
18MP0003436_decreased_susceptibility_to2.07608913
19MP0005409_darkened_coat_color2.03986176
20MP0008932_abnormal_embryonic_tissue2.03735138
21MP0009278_abnormal_bone_marrow1.98037689
22MP0005075_abnormal_melanosome_morpholog1.97819845
23MP0002163_abnormal_gland_morphology1.94769857
24MP0000920_abnormal_myelination1.79115889
25MP0000678_abnormal_parathyroid_gland1.78664760
26MP0006036_abnormal_mitochondrial_physio1.77382556
27MP0002132_abnormal_respiratory_system1.76780133
28MP0001986_abnormal_taste_sensitivity1.74091783
29MP0002396_abnormal_hematopoietic_system1.72190657
30MP0009333_abnormal_splenocyte_physiolog1.72098471
31MP0003186_abnormal_redox_activity1.69262986
32MP0005671_abnormal_response_to1.69175376
33MP0003718_maternal_effect1.66643444
34MP0003786_premature_aging1.66124052
35MP0004381_abnormal_hair_follicle1.59707676
36MP0000372_irregular_coat_pigmentation1.58653391
37MP0000858_altered_metastatic_potential1.58245249
38MP0003763_abnormal_thymus_physiology1.58124929
39MP0005501_abnormal_skin_physiology1.57880914
40MP0001835_abnormal_antigen_presentation1.56416951
41MP0002148_abnormal_hypersensitivity_rea1.55086436
42MP0002095_abnormal_skin_pigmentation1.53808740
43MP0003656_abnormal_erythrocyte_physiolo1.52585533
44MP0004142_abnormal_muscle_tone1.51626469
45MP0008007_abnormal_cellular_replicative1.51611416
46MP0003123_paternal_imprinting1.39114114
47MP0005464_abnormal_platelet_physiology1.38506682
48MP0009785_altered_susceptibility_to1.36328588
49MP0005174_abnormal_tail_pigmentation1.36238063
50MP0006292_abnormal_olfactory_placode1.35357714
51MP0002938_white_spotting1.34906525
52MP0002796_impaired_skin_barrier1.33793230
53MP0004858_abnormal_nervous_system1.33680427
54MP0008877_abnormal_DNA_methylation1.32204853
55MP0008260_abnormal_autophagy1.32027668
56MP0001661_extended_life_span1.31050567
57MP0001853_heart_inflammation1.30878242
58MP0000015_abnormal_ear_pigmentation1.30734912
59MP0001188_hyperpigmentation1.28076570
60MP0002877_abnormal_melanocyte_morpholog1.25411389
61MP0010030_abnormal_orbit_morphology1.23350779
62MP0003303_peritoneal_inflammation1.22388337
63MP0006035_abnormal_mitochondrial_morpho1.21882651
64MP0003705_abnormal_hypodermis_morpholog1.21027417
65MP0005171_absent_coat_pigmentation1.20229746
66MP0000490_abnormal_crypts_of1.19632808
67MP0002398_abnormal_bone_marrow1.19420768
68MP0004233_abnormal_muscle_weight1.17907642
69MP0000350_abnormal_cell_proliferation1.17811528
70MP0005410_abnormal_fertilization1.17303374
71MP0005000_abnormal_immune_tolerance1.15524591
72MP0000750_abnormal_muscle_regeneration1.14704880
73MP0003075_altered_response_to1.14551836
74MP0005025_abnormal_response_to1.12083033
75MP0002420_abnormal_adaptive_immunity1.11525019
76MP0005379_endocrine/exocrine_gland_phen1.10868376
77MP0001819_abnormal_immune_cell1.09650132
78MP0001727_abnormal_embryo_implantation1.08878220
79MP0005408_hypopigmentation1.08595551
80MP0003806_abnormal_nucleotide_metabolis1.07706633
81MP0000343_altered_response_to1.07152904
82MP0002736_abnormal_nociception_after1.06344745
83MP0005451_abnormal_body_composition1.06088203
84MP0002723_abnormal_immune_serum1.04729504
85MP0009697_abnormal_copulation1.04434805
86MP0000689_abnormal_spleen_morphology1.03384390
87MP0002722_abnormal_immune_system1.02408848
88MP0001545_abnormal_hematopoietic_system1.02390372
89MP0005397_hematopoietic_system_phenotyp1.02390372
90MP0005666_abnormal_adipose_tissue1.01814352
91MP0002080_prenatal_lethality1.01348125
92MP0000747_muscle_weakness1.00856351
93MP0001849_ear_inflammation1.00496248
94MP0002429_abnormal_blood_cell0.99462050
95MP0008789_abnormal_olfactory_epithelium0.98526780
96MP0000716_abnormal_immune_system0.98280561
97MP0002102_abnormal_ear_morphology0.96320093
98MP0001800_abnormal_humoral_immune0.94343390
99MP0002452_abnormal_antigen_presenting0.94325711
100MP0001790_abnormal_immune_system0.94056889
101MP0005387_immune_system_phenotype0.94056889
102MP0000681_abnormal_thyroid_gland0.93691668
103MP0001485_abnormal_pinna_reflex0.93650216
104MP0000685_abnormal_immune_system0.93138270
105MP0000313_abnormal_cell_death0.92841865
106MP0001873_stomach_inflammation0.92379423
107MP0003315_abnormal_perineum_morphology0.91449794
108MP0001764_abnormal_homeostasis0.90943138
109MP0002210_abnormal_sex_determination0.89038576
110MP0001845_abnormal_inflammatory_respons0.87769625
111MP0008469_abnormal_protein_level0.87679730
112MP0002653_abnormal_ependyma_morphology0.87202304
113MP0001929_abnormal_gametogenesis0.86323450
114MP0000703_abnormal_thymus_morphology0.86046257
115MP0006054_spinal_hemorrhage0.85943334
116MP0001533_abnormal_skeleton_physiology0.84128855
117MP0005319_abnormal_enzyme/_coenzyme0.83530889
118MP0005375_adipose_tissue_phenotype0.82871012
119MP0003724_increased_susceptibility_to0.82205232
120MP0004947_skin_inflammation0.81990960
121MP0002751_abnormal_autonomic_nervous0.81380201
122MP0001881_abnormal_mammary_gland0.81204554
123MP0002638_abnormal_pupillary_reflex0.79645384
124MP0001542_abnormal_bone_strength0.78864463
125MP0000465_gastrointestinal_hemorrhage0.78395545
126MP0003453_abnormal_keratinocyte_physiol0.77876848
127MP0000003_abnormal_adipose_tissue0.77433789
128MP0002419_abnormal_innate_immunity0.77022732
129MP0005330_cardiomyopathy0.76950853
130MP0000566_synostosis0.76942832
131MP0003172_abnormal_lysosome_physiology0.76297305
132MP0002019_abnormal_tumor_incidence0.76027882
133MP0005384_cellular_phenotype0.76026097
134MP0001145_abnormal_male_reproductive0.75719538
135MP0004742_abnormal_vestibular_system0.75506161
136MP0010155_abnormal_intestine_physiology0.74458774
137MP0002160_abnormal_reproductive_system0.74172930
138MP0002272_abnormal_nervous_system0.73970771
139MP0002405_respiratory_system_inflammati0.73206784
140MP0005670_abnormal_white_adipose0.71571503
141MP0003448_altered_tumor_morphology0.71470647
142MP0000358_abnormal_cell_content/0.68990660
143MP0001730_embryonic_growth_arrest0.67641741
144MP0001968_abnormal_touch/_nociception0.67219911
145MP0004808_abnormal_hematopoietic_stem0.66888046
146MP0002277_abnormal_respiratory_mucosa0.66752626
147MP0003866_abnormal_defecation0.65478442
148MP0003950_abnormal_plasma_membrane0.64879579
149MP0003938_abnormal_ear_development0.64737675
150MP0000653_abnormal_sex_gland0.64481613

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.30623887
2Abnormal number of erythroid precursors (HP:0012131)5.09129262
3Acute necrotizing encephalopathy (HP:0006965)5.05617823
4Mitochondrial inheritance (HP:0001427)4.94654210
5Hepatocellular necrosis (HP:0001404)4.58418481
6Abnormal mitochondria in muscle tissue (HP:0008316)4.48924332
7Increased hepatocellular lipid droplets (HP:0006565)4.39373068
83-Methylglutaconic aciduria (HP:0003535)4.23017594
9Increased CSF lactate (HP:0002490)4.16485753
10Progressive macrocephaly (HP:0004481)4.03047585
11Cerebral hypomyelination (HP:0006808)3.96404740
12Ragged-red muscle fibers (HP:0003200)3.87177451
13Renal Fanconi syndrome (HP:0001994)3.82107139
14Acute encephalopathy (HP:0006846)3.81669280
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.81306053
16Hepatic necrosis (HP:0002605)3.80514145
17Reticulocytopenia (HP:0001896)3.77240581
18Lipid accumulation in hepatocytes (HP:0006561)3.73040115
19Decreased activity of mitochondrial respiratory chain (HP:0008972)3.69958101
20Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.69958101
21Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.62923053
22Abnormality of glycolysis (HP:0004366)3.59385071
23Increased serum pyruvate (HP:0003542)3.59385071
24Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.55705254
25Macrocytic anemia (HP:0001972)3.35508545
26Exertional dyspnea (HP:0002875)3.29725745
27Abnormality of the heme biosynthetic pathway (HP:0010472)3.23418085
28Increased serum lactate (HP:0002151)3.22317484
29Birth length less than 3rd percentile (HP:0003561)3.15734325
30Increased intramyocellular lipid droplets (HP:0012240)3.00537896
31Progressive muscle weakness (HP:0003323)2.99975387
32Testicular atrophy (HP:0000029)2.99421189
33Type I transferrin isoform profile (HP:0003642)2.99278590
34Parakeratosis (HP:0001036)2.93584947
35Aplastic anemia (HP:0001915)2.91997762
36Pallor (HP:0000980)2.91525473
37Respiratory difficulties (HP:0002880)2.91307887
38Aplasia/Hypoplasia of the sacrum (HP:0008517)2.90983864
39Respiratory failure (HP:0002878)2.89408192
40Leukodystrophy (HP:0002415)2.87212869
41Exercise intolerance (HP:0003546)2.86616441
42Lactic acidosis (HP:0003128)2.70357695
43Broad distal phalanx of finger (HP:0009836)2.66605409
44Multiple enchondromatosis (HP:0005701)2.64712022
45Vertebral compression fractures (HP:0002953)2.60356750
46Breast hypoplasia (HP:0003187)2.55482875
47Myopathic facies (HP:0002058)2.46610223
48CNS hypomyelination (HP:0003429)2.45323232
49Achilles tendon contracture (HP:0001771)2.44522714
50Optic disc pallor (HP:0000543)2.41645730
51Hypertensive crisis (HP:0100735)2.39110393
52Abnormal gallbladder physiology (HP:0012438)2.36852508
53Cholecystitis (HP:0001082)2.36852508
54Rough bone trabeculation (HP:0100670)2.35670577
55Increased muscle lipid content (HP:0009058)2.34332331
56IgM deficiency (HP:0002850)2.34238749
57Congenital ichthyosiform erythroderma (HP:0007431)2.32182204
58Microvesicular hepatic steatosis (HP:0001414)2.31558712
59Type 2 muscle fiber atrophy (HP:0003554)2.29786246
60Abnormality of renal resorption (HP:0011038)2.29556120
61Abnormality of the umbilical cord (HP:0010881)2.27553705
62Hypokinesia (HP:0002375)2.27404113
63Trismus (HP:0000211)2.27009911
64Prolonged neonatal jaundice (HP:0006579)2.26544133
65Oral leukoplakia (HP:0002745)2.25662442
66Abnormality of glycolipid metabolism (HP:0010969)2.25310488
67Abnormality of liposaccharide metabolism (HP:0010968)2.25310488
68Abnormality of glycosphingolipid metabolism (HP:0004343)2.25310488
69Increased cerebral lipofuscin (HP:0011813)2.23787404
70Cerebral edema (HP:0002181)2.20285366
71Centrally nucleated skeletal muscle fibers (HP:0003687)2.18400173
72Increased neuronal autofluorescent lipopigment (HP:0002074)2.17455756
73Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.16271279
74Abnormal protein N-linked glycosylation (HP:0012347)2.16271279
75Abnormal protein glycosylation (HP:0012346)2.16271279
76Abnormal glycosylation (HP:0012345)2.16271279
77Muscle fiber atrophy (HP:0100295)2.13938514
78Increased serum ferritin (HP:0003281)2.11843192
79Obstructive lung disease (HP:0006536)2.09421175
80Chronic obstructive pulmonary disease (HP:0006510)2.09421175
81Carpal bone hypoplasia (HP:0001498)2.06895060
82CNS demyelination (HP:0007305)2.05821923
83Pancytopenia (HP:0001876)2.03970135
84Distal lower limb muscle weakness (HP:0009053)2.03778571
85Abnormality of the Achilles tendon (HP:0005109)2.03131327
86Emotional lability (HP:0000712)2.02462302
87Abnormality of reticulocytes (HP:0004312)1.98268499
88Petechiae (HP:0000967)1.97073344
89Patchy hypopigmentation of hair (HP:0011365)1.96657830
90Hypoplasia of the capital femoral epiphysis (HP:0003090)1.96416857
91Postnatal microcephaly (HP:0005484)1.95360722
92Abnormality of dicarboxylic acid metabolism (HP:0010995)1.94719767
93Dicarboxylic aciduria (HP:0003215)1.94719767
94Progressive neurologic deterioration (HP:0002344)1.93590145
95Abnormality of the fetal cardiovascular system (HP:0010948)1.92326111
96Abnormal umbilical cord blood vessels (HP:0011403)1.92326111
97Single umbilical artery (HP:0001195)1.92326111
98Neuroendocrine neoplasm (HP:0100634)1.90228072
99Premature graying of hair (HP:0002216)1.89165925
100Increased IgM level (HP:0003496)1.89153647
101Sensory axonal neuropathy (HP:0003390)1.87402079
102Bulbar palsy (HP:0001283)1.87312118
103Recurrent abscess formation (HP:0002722)1.85266370
104Abnormal trabecular bone morphology (HP:0100671)1.84707507
105Asplenia (HP:0001746)1.84289915
106Poor head control (HP:0002421)1.83196556
107Fasciculations (HP:0002380)1.81831400
108Generalized amyotrophy (HP:0003700)1.80126702
109Medial flaring of the eyebrow (HP:0010747)1.79044960
110Recurrent bacterial skin infections (HP:0005406)1.78886080
111Opisthotonus (HP:0002179)1.78087901
112IgG deficiency (HP:0004315)1.77891043
113Abnormality of the distal phalanges of the toes (HP:0010182)1.77155540
114Rhabdomyolysis (HP:0003201)1.76194558
115Dysphonia (HP:0001618)1.75756556
116Abnormalities of placenta or umbilical cord (HP:0001194)1.74905423
117Cholelithiasis (HP:0001081)1.74866261
118Hepatosplenomegaly (HP:0001433)1.74663479
119Elevated erythrocyte sedimentation rate (HP:0003565)1.74005342
120Hyperparathyroidism (HP:0000843)1.73132143
121Death in infancy (HP:0001522)1.72952217
122Delusions (HP:0000746)1.72944691
123Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.70982170
124Duplicated collecting system (HP:0000081)1.70578392
125Cerebral palsy (HP:0100021)1.69949596
126Abnormality of macrophages (HP:0004311)1.69725313
127Microretrognathia (HP:0000308)1.69285028
128Hypergonadotropic hypogonadism (HP:0000815)1.68630445
129Hypoplastic pelvis (HP:0008839)1.65364700
130Bone marrow hypocellularity (HP:0005528)1.65032895
131Abnormality of the preputium (HP:0100587)1.64913026
132Aplasia/Hypoplasia of the spleen (HP:0010451)1.64089562
133Abnormal lung lobation (HP:0002101)1.63115374
134Secondary amenorrhea (HP:0000869)1.61061464
135Absent epiphyses (HP:0010577)1.60333127
136Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.60333127
137Sparse eyelashes (HP:0000653)1.59968564
138Triphalangeal thumb (HP:0001199)1.58716238
139Aplasia/hypoplasia of the uterus (HP:0008684)1.56507722
140Thrombocytosis (HP:0001894)1.55330486
141Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.54963814
142Degeneration of the lateral corticospinal tracts (HP:0002314)1.54963814
143Erythema (HP:0010783)1.54854901
144Spastic paraparesis (HP:0002313)1.54755417
145Abnormality of placental membranes (HP:0011409)1.54011729
146Amniotic constriction ring (HP:0009775)1.54011729
147Reduced antithrombin III activity (HP:0001976)1.53798000
148Irregular epiphyses (HP:0010582)1.52816622
149White forelock (HP:0002211)1.51478256
150Abnormality of urine glucose concentration (HP:0011016)1.50627555
151Glycosuria (HP:0003076)1.50627555

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.35379564
2VRK24.08166668
3STK163.73152540
4NME23.44636518
5SMG13.19490401
6VRK12.91485930
7IRAK32.83313428
8WEE12.77469198
9EIF2AK12.66057450
10TRIB32.50678447
11CDK192.41025375
12PBK2.29887031
13EIF2AK32.15924051
14PLK41.97681615
15TESK21.97509437
16PIM21.94543429
17STK391.87509509
18ERN11.85237591
19MAP3K121.84509563
20LIMK11.76405755
21TAOK21.75905892
22SCYL21.70643904
23TNIK1.68953502
24SRPK11.66038219
25TLK11.65926674
26OXSR11.62957435
27PRPF4B1.61676125
28MAPKAPK51.59885666
29ARAF1.54339792
30NME11.51386145
31MST41.46428632
32TSSK61.43720831
33MAP2K31.40074750
34MUSK1.39056646
35MKNK11.36006189
36DYRK31.34292216
37CCNB11.32076608
38KDR1.30108532
39BRSK21.29332648
40DYRK21.28740491
41CDC71.28285837
42PAK41.27888224
43NEK11.21834310
44CLK11.19102832
45TBK11.17638444
46BCR1.16083703
47ACVR1B1.14136270
48IRAK41.13296971
49MAP4K11.12487454
50CSNK1G31.05286537
51CASK1.04544233
52DAPK11.02871683
53KIT1.02647022
54TXK1.01902405
55AURKA1.00807117
56MYLK0.99971659
57MAP3K80.98221124
58BRAF0.97573619
59PRKD30.97074211
60TESK10.97024202
61DAPK30.92575290
62BRSK10.92079561
63CDK80.91867911
64PLK10.89799467
65ABL20.87757639
66ILK0.87276973
67BLK0.86684835
68RPS6KA50.84730572
69ADRBK20.82240061
70ZAK0.81871081
71SIK10.81400450
72EPHA20.80730913
73TAOK10.79620762
74IRAK20.78000140
75TEC0.77147373
76AURKB0.76954003
77PRKCI0.76699405
78PAK10.76495105
79PLK30.74353678
80MAP3K30.74153905
81GRK60.70562606
82ICK0.69054859
83TYK20.68756183
84MAPK130.68526166
85UHMK10.68427513
86LYN0.64731775
87CSNK2A10.63942957
88MAP2K20.61998159
89GRK70.61608787
90CDK40.61301708
91BTK0.60894965
92SYK0.60827118
93BMPR1B0.60269660
94EIF2AK20.60255022
95TAF10.60209639
96TRPM70.59351428
97PRKD20.58823948
98EEF2K0.58595409
99STK40.58469713
100CDK70.57004813
101CSNK2A20.54081018
102CSNK1G10.53905265
103CSF1R0.53424283
104YES10.53004943
105PKN10.52617730
106STK100.51810933
107CAMK2B0.51554284
108BMX0.51203824
109MAP3K110.50924568
110CDK90.50257882
111RPS6KB20.48793945
112MAPKAPK30.48632901
113AKT20.47760220
114NEK20.47464004
115BCKDK0.47320290
116MKNK20.47022777
117MAPK110.47005437
118MAP3K100.46891803
119MAP3K10.46579148
120CHEK20.46394444
121CDK140.45787251
122TTK0.45528524
123CDK11A0.45442279
124CSNK1A1L0.45030616
125TTN0.43206044
126CDK180.43127188
127IKBKB0.42875135
128RPS6KC10.42178526
129RPS6KL10.42178526
130GRK50.41642638
131CDK30.41598682
132CDK150.41578166
133LCK0.41380032
134PNCK0.41152885
135RAF10.41148587
136ATR0.40609074
137PDK20.40192342
138ROCK20.37734257
139CSNK1G20.36691812
140RIPK40.35450033
141FES0.35196152
142TNK20.34138189
143NEK60.34042980
144LRRK20.33376859
145ZAP700.33226329
146PRKG20.33138859
147RPS6KA40.32816156
148CAMK2G0.32809615
149CHEK10.32237040
150PIM10.31960525
151PTK60.31783780
152PDPK10.30664780

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.85392408
2Proteasome_Homo sapiens_hsa030504.60636437
3RNA polymerase_Homo sapiens_hsa030203.73961027
4Oxidative phosphorylation_Homo sapiens_hsa001903.73578349
5DNA replication_Homo sapiens_hsa030303.48419889
6Parkinsons disease_Homo sapiens_hsa050123.25351476
7Protein export_Homo sapiens_hsa030602.89855475
8Mismatch repair_Homo sapiens_hsa034302.80370542
9Spliceosome_Homo sapiens_hsa030402.46483355
10Huntingtons disease_Homo sapiens_hsa050162.45754382
11Pyrimidine metabolism_Homo sapiens_hsa002402.41741693
12Homologous recombination_Homo sapiens_hsa034402.39110332
13Nucleotide excision repair_Homo sapiens_hsa034202.34221461
14Alzheimers disease_Homo sapiens_hsa050102.28412833
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.13507164
162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.09855770
17Base excision repair_Homo sapiens_hsa034102.09444185
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.99224016
19Basal transcription factors_Homo sapiens_hsa030221.93452588
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.88409627
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.84354544
22Biosynthesis of amino acids_Homo sapiens_hsa012301.72686660
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.67961635
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.66768530
25Non-homologous end-joining_Homo sapiens_hsa034501.55293773
26RNA transport_Homo sapiens_hsa030131.54492321
27Fanconi anemia pathway_Homo sapiens_hsa034601.47208231
28RNA degradation_Homo sapiens_hsa030181.42847985
29Carbon metabolism_Homo sapiens_hsa012001.41448868
30Purine metabolism_Homo sapiens_hsa002301.40665051
31Galactose metabolism_Homo sapiens_hsa000521.38479818
32Fructose and mannose metabolism_Homo sapiens_hsa000511.37408668
33Cell cycle_Homo sapiens_hsa041101.35833430
34Fatty acid elongation_Homo sapiens_hsa000621.25633950
35SNARE interactions in vesicular transport_Homo sapiens_hsa041301.19759818
36Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.18863264
37Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.04331112
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.04109726
39Cardiac muscle contraction_Homo sapiens_hsa042600.98905825
40Cyanoamino acid metabolism_Homo sapiens_hsa004600.96545673
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.96180636
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.94976821
43Folate biosynthesis_Homo sapiens_hsa007900.91905721
44Epstein-Barr virus infection_Homo sapiens_hsa051690.91599854
45Bladder cancer_Homo sapiens_hsa052190.86822694
46Ether lipid metabolism_Homo sapiens_hsa005650.85587616
47Vitamin B6 metabolism_Homo sapiens_hsa007500.85123801
48Primary immunodeficiency_Homo sapiens_hsa053400.85089080
49Arachidonic acid metabolism_Homo sapiens_hsa005900.82863347
50Collecting duct acid secretion_Homo sapiens_hsa049660.82350559
51Glutathione metabolism_Homo sapiens_hsa004800.81575871
52Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.80703464
53Lysosome_Homo sapiens_hsa041420.80488581
54Graft-versus-host disease_Homo sapiens_hsa053320.76185589
55Pyruvate metabolism_Homo sapiens_hsa006200.72695781
56Steroid biosynthesis_Homo sapiens_hsa001000.70939001
57p53 signaling pathway_Homo sapiens_hsa041150.69723084
58Vibrio cholerae infection_Homo sapiens_hsa051100.69579763
59Sphingolipid metabolism_Homo sapiens_hsa006000.69511157
60Systemic lupus erythematosus_Homo sapiens_hsa053220.67269297
61Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66711516
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.65008280
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62662977
64Asthma_Homo sapiens_hsa053100.61997095
65Metabolic pathways_Homo sapiens_hsa011000.61499487
66Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.61390172
67Linoleic acid metabolism_Homo sapiens_hsa005910.60766616
68Rheumatoid arthritis_Homo sapiens_hsa053230.60689998
69Pentose phosphate pathway_Homo sapiens_hsa000300.57990357
70Allograft rejection_Homo sapiens_hsa053300.57275357
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.57073168
72HTLV-I infection_Homo sapiens_hsa051660.56813416
73Acute myeloid leukemia_Homo sapiens_hsa052210.56307457
74Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.52753859
75Shigellosis_Homo sapiens_hsa051310.52720592
76Regulation of autophagy_Homo sapiens_hsa041400.52373368
77Autoimmune thyroid disease_Homo sapiens_hsa053200.51982372
78Antigen processing and presentation_Homo sapiens_hsa046120.51286498
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.50714542
80Phenylalanine metabolism_Homo sapiens_hsa003600.49318363
81Hematopoietic cell lineage_Homo sapiens_hsa046400.48934069
82mRNA surveillance pathway_Homo sapiens_hsa030150.47526287
83Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46539568
84Sulfur relay system_Homo sapiens_hsa041220.45065703
85Toll-like receptor signaling pathway_Homo sapiens_hsa046200.44275531
86Viral myocarditis_Homo sapiens_hsa054160.43370865
87Prion diseases_Homo sapiens_hsa050200.41779607
88Phagosome_Homo sapiens_hsa041450.40707825
89Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.40382431
90Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.40101271
91Alcoholism_Homo sapiens_hsa050340.38912090
92Oocyte meiosis_Homo sapiens_hsa041140.38899044
93Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.37176843
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36899719
95Herpes simplex infection_Homo sapiens_hsa051680.36266365
96Intestinal immune network for IgA production_Homo sapiens_hsa046720.35778886
97Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.35621882
98Peroxisome_Homo sapiens_hsa041460.35184497
99Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34567780
100N-Glycan biosynthesis_Homo sapiens_hsa005100.33066025
101One carbon pool by folate_Homo sapiens_hsa006700.31766819
102Endocytosis_Homo sapiens_hsa041440.31671294
103Leishmaniasis_Homo sapiens_hsa051400.30491303
104Notch signaling pathway_Homo sapiens_hsa043300.28923650
105Tuberculosis_Homo sapiens_hsa051520.28892725
106Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.28055701
107Osteoclast differentiation_Homo sapiens_hsa043800.27730628
108Non-small cell lung cancer_Homo sapiens_hsa052230.26890431
109Measles_Homo sapiens_hsa051620.24679352
110Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.23156106
111Viral carcinogenesis_Homo sapiens_hsa052030.22772396
112Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.21979683
113Cysteine and methionine metabolism_Homo sapiens_hsa002700.21420196
114Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.20834209
115Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.20310397
116Legionellosis_Homo sapiens_hsa051340.19417407
117Serotonergic synapse_Homo sapiens_hsa047260.18681859
118Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.18073821
119Pertussis_Homo sapiens_hsa051330.17426948
120Phototransduction_Homo sapiens_hsa047440.16717728
121Malaria_Homo sapiens_hsa051440.16710077
122Other glycan degradation_Homo sapiens_hsa005110.16559929
123NOD-like receptor signaling pathway_Homo sapiens_hsa046210.14415682
124Drug metabolism - other enzymes_Homo sapiens_hsa009830.13417045
125Sulfur metabolism_Homo sapiens_hsa009200.13048049
126RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.11789432
127Salmonella infection_Homo sapiens_hsa051320.11485382
128Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.11471836
129Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.09488834
130Apoptosis_Homo sapiens_hsa042100.07897968
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.06681423
132Sphingolipid signaling pathway_Homo sapiens_hsa040710.05959300
133NF-kappa B signaling pathway_Homo sapiens_hsa040640.05921716
134Arginine and proline metabolism_Homo sapiens_hsa003300.05061065
135Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.04966413

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