Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 5.49513405 |
2 | ribosomal small subunit biogenesis (GO:0042274) | 5.23475350 |
3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.12552240 |
4 | proteasome assembly (GO:0043248) | 5.09622858 |
5 | viral transcription (GO:0019083) | 5.00130136 |
6 | DNA deamination (GO:0045006) | 4.98774772 |
7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.86301126 |
8 | ATP synthesis coupled proton transport (GO:0015986) | 4.86301126 |
9 | translational termination (GO:0006415) | 4.83517275 |
10 | protein maturation by protein folding (GO:0022417) | 4.69443104 |
11 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.63511256 |
12 | chaperone-mediated protein transport (GO:0072321) | 4.57100364 |
13 | cotranslational protein targeting to membrane (GO:0006613) | 4.56278834 |
14 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.53422132 |
15 | protein targeting to ER (GO:0045047) | 4.47882946 |
16 | maturation of SSU-rRNA (GO:0030490) | 4.38516949 |
17 | protein neddylation (GO:0045116) | 4.29802064 |
18 | protein localization to endoplasmic reticulum (GO:0070972) | 4.29509436 |
19 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.26544729 |
20 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.25660881 |
21 | translational elongation (GO:0006414) | 4.18977405 |
22 | termination of RNA polymerase III transcription (GO:0006386) | 4.18864877 |
23 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.18864877 |
24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.04655383 |
25 | GDP-mannose metabolic process (GO:0019673) | 4.04490274 |
26 | negative regulation of ligase activity (GO:0051352) | 4.01308090 |
27 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.01308090 |
28 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.97597867 |
29 | 7-methylguanosine mRNA capping (GO:0006370) | 3.97312073 |
30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.95099396 |
31 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.95099396 |
32 | NADH dehydrogenase complex assembly (GO:0010257) | 3.95099396 |
33 | 7-methylguanosine RNA capping (GO:0009452) | 3.91954596 |
34 | RNA capping (GO:0036260) | 3.91954596 |
35 | viral life cycle (GO:0019058) | 3.91153212 |
36 | cellular protein complex disassembly (GO:0043624) | 3.90540990 |
37 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.90224234 |
38 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.87944758 |
39 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.85464452 |
40 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.85399648 |
41 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.84213580 |
42 | protein complex biogenesis (GO:0070271) | 3.83900135 |
43 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.83806802 |
44 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.81798331 |
45 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.77521463 |
46 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.77521463 |
47 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.75943796 |
48 | translational initiation (GO:0006413) | 3.75579548 |
49 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.75271404 |
50 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.74539572 |
51 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.74539572 |
52 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.74539572 |
53 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.70596541 |
54 | translation (GO:0006412) | 3.69918623 |
55 | ribosomal large subunit biogenesis (GO:0042273) | 3.69821533 |
56 | respiratory electron transport chain (GO:0022904) | 3.67789524 |
57 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.66882256 |
58 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.64112764 |
59 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.61017645 |
60 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.61017645 |
61 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.60432297 |
62 | electron transport chain (GO:0022900) | 3.59636541 |
63 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.59359295 |
64 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.58031571 |
65 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.57465075 |
66 | DNA strand elongation (GO:0022616) | 3.56657217 |
67 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.56029503 |
68 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.54688554 |
69 | establishment of integrated proviral latency (GO:0075713) | 3.52881380 |
70 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.49313336 |
71 | GTP biosynthetic process (GO:0006183) | 3.45964149 |
72 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.43750923 |
73 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.43750923 |
74 | respiratory chain complex IV assembly (GO:0008535) | 3.40685696 |
75 | protein targeting to mitochondrion (GO:0006626) | 3.40525563 |
76 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.37049265 |
77 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.36362240 |
78 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.34551088 |
79 | deoxyribonucleotide catabolic process (GO:0009264) | 3.33444431 |
80 | telomere maintenance via recombination (GO:0000722) | 3.32527840 |
81 | protein complex disassembly (GO:0043241) | 3.31925554 |
82 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.29826252 |
83 | cullin deneddylation (GO:0010388) | 3.28508017 |
84 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.28328492 |
85 | establishment of protein localization to mitochondrion (GO:0072655) | 3.27799095 |
86 | protein deneddylation (GO:0000338) | 3.25587841 |
87 | positive regulation of ligase activity (GO:0051351) | 3.24198719 |
88 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.23993121 |
89 | deoxyribose phosphate catabolic process (GO:0046386) | 3.22673625 |
90 | cellular component biogenesis (GO:0044085) | 3.22321815 |
91 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 3.22041789 |
92 | CENP-A containing nucleosome assembly (GO:0034080) | 3.20590230 |
93 | establishment of viral latency (GO:0019043) | 3.17539275 |
94 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.16521568 |
95 | macromolecular complex disassembly (GO:0032984) | 3.14638648 |
96 | proline biosynthetic process (GO:0006561) | 3.14054776 |
97 | central nervous system myelination (GO:0022010) | 3.12894588 |
98 | axon ensheathment in central nervous system (GO:0032291) | 3.12894588 |
99 | pentose metabolic process (GO:0019321) | 3.12869291 |
100 | rRNA processing (GO:0006364) | 3.10554414 |
101 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.09923331 |
102 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.09833380 |
103 | oxidative phosphorylation (GO:0006119) | 3.09787861 |
104 | regulation of mitochondrial translation (GO:0070129) | 3.09374536 |
105 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.08076209 |
106 | CTP metabolic process (GO:0046036) | 3.06353154 |
107 | CTP biosynthetic process (GO:0006241) | 3.06353154 |
108 | pseudouridine synthesis (GO:0001522) | 3.05908701 |
109 | nucleotide salvage (GO:0043173) | 3.05459160 |
110 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.03196466 |
111 | UTP biosynthetic process (GO:0006228) | 3.03168045 |
112 | metallo-sulfur cluster assembly (GO:0031163) | 3.02692806 |
113 | iron-sulfur cluster assembly (GO:0016226) | 3.02692806 |
114 | spliceosomal snRNP assembly (GO:0000387) | 3.02410995 |
115 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.02281239 |
116 | base-excision repair, AP site formation (GO:0006285) | 3.01839240 |
117 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.01710998 |
118 | peptidyl-histidine modification (GO:0018202) | 3.01397945 |
119 | nuclear envelope reassembly (GO:0031468) | 2.99095323 |
120 | mitotic nuclear envelope reassembly (GO:0007084) | 2.99095323 |
121 | formation of translation preinitiation complex (GO:0001731) | 2.98664045 |
122 | regulation of ligase activity (GO:0051340) | 2.98259095 |
123 | UTP metabolic process (GO:0046051) | 2.97924151 |
124 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.96995163 |
125 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.96771535 |
126 | protein localization to mitochondrion (GO:0070585) | 2.96689202 |
127 | chromatin remodeling at centromere (GO:0031055) | 2.96266318 |
128 | pentose-phosphate shunt (GO:0006098) | 2.96097660 |
129 | protein targeting to membrane (GO:0006612) | 2.95766808 |
130 | DNA replication initiation (GO:0006270) | 2.95734409 |
131 | histone arginine methylation (GO:0034969) | 2.91749343 |
132 | purine nucleotide salvage (GO:0032261) | 2.91179705 |
133 | rRNA modification (GO:0000154) | 2.90983785 |
134 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 2.86261716 |
135 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.82177103 |
136 | ribosome biogenesis (GO:0042254) | 2.76299545 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.82007500 |
2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.78527213 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.41964844 |
4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.09249405 |
5 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.05429688 |
6 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.02645727 |
7 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.89747069 |
8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.71934006 |
9 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.62519312 |
10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.54493389 |
11 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.54377425 |
12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.50289593 |
13 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.49015598 |
14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.37840574 |
15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.12536740 |
16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.07567175 |
17 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.91239900 |
18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.81596596 |
19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.74883238 |
20 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.49682400 |
21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.40803436 |
22 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.40162818 |
23 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.39909192 |
24 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.38774012 |
25 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.37996477 |
26 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.36343460 |
27 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.33113836 |
28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.23201313 |
29 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.21626646 |
30 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.13084249 |
31 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.10585496 |
32 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.09896201 |
33 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.09524183 |
34 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.04151926 |
35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.02357505 |
36 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.99729095 |
37 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.97787589 |
38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.96042552 |
39 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.94905527 |
40 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.94744003 |
41 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.93044093 |
42 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.90570429 |
43 | MYC_22102868_ChIP-Seq_BL_Human | 1.87781090 |
44 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.86631443 |
45 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.79608987 |
46 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.79357075 |
47 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.76278292 |
48 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.73517263 |
49 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.72213476 |
50 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.72006790 |
51 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.68511934 |
52 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.66712018 |
53 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.64546707 |
54 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.64439026 |
55 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.58822019 |
56 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.56901117 |
57 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.48644110 |
58 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.45165536 |
59 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.43550141 |
60 | P68_20966046_ChIP-Seq_HELA_Human | 1.41560187 |
61 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.38675585 |
62 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.36986490 |
63 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.34858433 |
64 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31343960 |
65 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.30159669 |
66 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29402596 |
67 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.26614823 |
68 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.25462777 |
69 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.25054254 |
70 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.24084424 |
71 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.24005209 |
72 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.21890302 |
73 | MAF_26560356_Chip-Seq_TH2_Human | 1.21393989 |
74 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.21145323 |
75 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.20261679 |
76 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.19762405 |
77 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.19490251 |
78 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.19420607 |
79 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.18858987 |
80 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.18700912 |
81 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.17693705 |
82 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.17072058 |
83 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.17061124 |
84 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.16849795 |
85 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.15902882 |
86 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.15494713 |
87 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.14684153 |
88 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.14355626 |
89 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.14059525 |
90 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.13520252 |
91 | * FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.12533795 |
92 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.12274509 |
93 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.11228524 |
94 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.07990436 |
95 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.07552346 |
96 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.06063166 |
97 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.06012875 |
98 | MAF_26560356_Chip-Seq_TH1_Human | 1.05401463 |
99 | UTX_26944678_Chip-Seq_JUKART_Human | 1.05089797 |
100 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.05017533 |
101 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.04144266 |
102 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.04108366 |
103 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.02825101 |
104 | * CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.02209182 |
105 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.01184126 |
106 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00251001 |
107 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.99537748 |
108 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.98659055 |
109 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.97246642 |
110 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.96959261 |
111 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.96539576 |
112 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.93692400 |
113 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.93569541 |
114 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.92669003 |
115 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.91515923 |
116 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.90146524 |
117 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89407033 |
118 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.87141848 |
119 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.86043848 |
120 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84671027 |
121 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.83470808 |
122 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.81620505 |
123 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.81332560 |
124 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.80551936 |
125 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.79393934 |
126 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.77152090 |
127 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.76934125 |
128 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.76818707 |
129 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.76536441 |
130 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.72089191 |
131 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.70103012 |
132 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.70034649 |
133 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.69925325 |
134 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.68891734 |
135 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.67510702 |
136 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.66566043 |
137 | * TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.65192682 |
138 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.64666859 |
139 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.63319732 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009379_abnormal_foot_pigmentation | 3.50640983 |
2 | MP0005058_abnormal_lysosome_morphology | 3.24146906 |
3 | MP0001529_abnormal_vocalization | 3.17765711 |
4 | MP0003693_abnormal_embryo_hatching | 3.14289766 |
5 | MP0008057_abnormal_DNA_replication | 3.03827247 |
6 | MP0004147_increased_porphyrin_level | 2.88838892 |
7 | MP0004957_abnormal_blastocyst_morpholog | 2.66137366 |
8 | MP0001905_abnormal_dopamine_level | 2.43666153 |
9 | MP0009840_abnormal_foam_cell | 2.38395088 |
10 | MP0003880_abnormal_central_pattern | 2.35864163 |
11 | MP0004185_abnormal_adipocyte_glucose | 2.35744649 |
12 | MP0003191_abnormal_cellular_cholesterol | 2.34968165 |
13 | MP0010094_abnormal_chromosome_stability | 2.33442150 |
14 | MP0003077_abnormal_cell_cycle | 2.27650662 |
15 | MP0008058_abnormal_DNA_repair | 2.26227020 |
16 | MP0003136_yellow_coat_color | 2.13505314 |
17 | MP0003111_abnormal_nucleus_morphology | 2.08998109 |
18 | MP0003436_decreased_susceptibility_to | 2.07608913 |
19 | MP0005409_darkened_coat_color | 2.03986176 |
20 | MP0008932_abnormal_embryonic_tissue | 2.03735138 |
21 | MP0009278_abnormal_bone_marrow | 1.98037689 |
22 | MP0005075_abnormal_melanosome_morpholog | 1.97819845 |
23 | MP0002163_abnormal_gland_morphology | 1.94769857 |
24 | MP0000920_abnormal_myelination | 1.79115889 |
25 | MP0000678_abnormal_parathyroid_gland | 1.78664760 |
26 | MP0006036_abnormal_mitochondrial_physio | 1.77382556 |
27 | MP0002132_abnormal_respiratory_system | 1.76780133 |
28 | MP0001986_abnormal_taste_sensitivity | 1.74091783 |
29 | MP0002396_abnormal_hematopoietic_system | 1.72190657 |
30 | MP0009333_abnormal_splenocyte_physiolog | 1.72098471 |
31 | MP0003186_abnormal_redox_activity | 1.69262986 |
32 | MP0005671_abnormal_response_to | 1.69175376 |
33 | MP0003718_maternal_effect | 1.66643444 |
34 | MP0003786_premature_aging | 1.66124052 |
35 | MP0004381_abnormal_hair_follicle | 1.59707676 |
36 | MP0000372_irregular_coat_pigmentation | 1.58653391 |
37 | MP0000858_altered_metastatic_potential | 1.58245249 |
38 | MP0003763_abnormal_thymus_physiology | 1.58124929 |
39 | MP0005501_abnormal_skin_physiology | 1.57880914 |
40 | MP0001835_abnormal_antigen_presentation | 1.56416951 |
41 | MP0002148_abnormal_hypersensitivity_rea | 1.55086436 |
42 | MP0002095_abnormal_skin_pigmentation | 1.53808740 |
43 | MP0003656_abnormal_erythrocyte_physiolo | 1.52585533 |
44 | MP0004142_abnormal_muscle_tone | 1.51626469 |
45 | MP0008007_abnormal_cellular_replicative | 1.51611416 |
46 | MP0003123_paternal_imprinting | 1.39114114 |
47 | MP0005464_abnormal_platelet_physiology | 1.38506682 |
48 | MP0009785_altered_susceptibility_to | 1.36328588 |
49 | MP0005174_abnormal_tail_pigmentation | 1.36238063 |
50 | MP0006292_abnormal_olfactory_placode | 1.35357714 |
51 | MP0002938_white_spotting | 1.34906525 |
52 | MP0002796_impaired_skin_barrier | 1.33793230 |
53 | MP0004858_abnormal_nervous_system | 1.33680427 |
54 | MP0008877_abnormal_DNA_methylation | 1.32204853 |
55 | MP0008260_abnormal_autophagy | 1.32027668 |
56 | MP0001661_extended_life_span | 1.31050567 |
57 | MP0001853_heart_inflammation | 1.30878242 |
58 | MP0000015_abnormal_ear_pigmentation | 1.30734912 |
59 | MP0001188_hyperpigmentation | 1.28076570 |
60 | MP0002877_abnormal_melanocyte_morpholog | 1.25411389 |
61 | MP0010030_abnormal_orbit_morphology | 1.23350779 |
62 | MP0003303_peritoneal_inflammation | 1.22388337 |
63 | MP0006035_abnormal_mitochondrial_morpho | 1.21882651 |
64 | MP0003705_abnormal_hypodermis_morpholog | 1.21027417 |
65 | MP0005171_absent_coat_pigmentation | 1.20229746 |
66 | MP0000490_abnormal_crypts_of | 1.19632808 |
67 | MP0002398_abnormal_bone_marrow | 1.19420768 |
68 | MP0004233_abnormal_muscle_weight | 1.17907642 |
69 | MP0000350_abnormal_cell_proliferation | 1.17811528 |
70 | MP0005410_abnormal_fertilization | 1.17303374 |
71 | MP0005000_abnormal_immune_tolerance | 1.15524591 |
72 | MP0000750_abnormal_muscle_regeneration | 1.14704880 |
73 | MP0003075_altered_response_to | 1.14551836 |
74 | MP0005025_abnormal_response_to | 1.12083033 |
75 | MP0002420_abnormal_adaptive_immunity | 1.11525019 |
76 | MP0005379_endocrine/exocrine_gland_phen | 1.10868376 |
77 | MP0001819_abnormal_immune_cell | 1.09650132 |
78 | MP0001727_abnormal_embryo_implantation | 1.08878220 |
79 | MP0005408_hypopigmentation | 1.08595551 |
80 | MP0003806_abnormal_nucleotide_metabolis | 1.07706633 |
81 | MP0000343_altered_response_to | 1.07152904 |
82 | MP0002736_abnormal_nociception_after | 1.06344745 |
83 | MP0005451_abnormal_body_composition | 1.06088203 |
84 | MP0002723_abnormal_immune_serum | 1.04729504 |
85 | MP0009697_abnormal_copulation | 1.04434805 |
86 | MP0000689_abnormal_spleen_morphology | 1.03384390 |
87 | MP0002722_abnormal_immune_system | 1.02408848 |
88 | MP0001545_abnormal_hematopoietic_system | 1.02390372 |
89 | MP0005397_hematopoietic_system_phenotyp | 1.02390372 |
90 | MP0005666_abnormal_adipose_tissue | 1.01814352 |
91 | MP0002080_prenatal_lethality | 1.01348125 |
92 | MP0000747_muscle_weakness | 1.00856351 |
93 | MP0001849_ear_inflammation | 1.00496248 |
94 | MP0002429_abnormal_blood_cell | 0.99462050 |
95 | MP0008789_abnormal_olfactory_epithelium | 0.98526780 |
96 | MP0000716_abnormal_immune_system | 0.98280561 |
97 | MP0002102_abnormal_ear_morphology | 0.96320093 |
98 | MP0001800_abnormal_humoral_immune | 0.94343390 |
99 | MP0002452_abnormal_antigen_presenting | 0.94325711 |
100 | MP0001790_abnormal_immune_system | 0.94056889 |
101 | MP0005387_immune_system_phenotype | 0.94056889 |
102 | MP0000681_abnormal_thyroid_gland | 0.93691668 |
103 | MP0001485_abnormal_pinna_reflex | 0.93650216 |
104 | MP0000685_abnormal_immune_system | 0.93138270 |
105 | MP0000313_abnormal_cell_death | 0.92841865 |
106 | MP0001873_stomach_inflammation | 0.92379423 |
107 | MP0003315_abnormal_perineum_morphology | 0.91449794 |
108 | MP0001764_abnormal_homeostasis | 0.90943138 |
109 | MP0002210_abnormal_sex_determination | 0.89038576 |
110 | MP0001845_abnormal_inflammatory_respons | 0.87769625 |
111 | MP0008469_abnormal_protein_level | 0.87679730 |
112 | MP0002653_abnormal_ependyma_morphology | 0.87202304 |
113 | MP0001929_abnormal_gametogenesis | 0.86323450 |
114 | MP0000703_abnormal_thymus_morphology | 0.86046257 |
115 | MP0006054_spinal_hemorrhage | 0.85943334 |
116 | MP0001533_abnormal_skeleton_physiology | 0.84128855 |
117 | MP0005319_abnormal_enzyme/_coenzyme | 0.83530889 |
118 | MP0005375_adipose_tissue_phenotype | 0.82871012 |
119 | MP0003724_increased_susceptibility_to | 0.82205232 |
120 | MP0004947_skin_inflammation | 0.81990960 |
121 | MP0002751_abnormal_autonomic_nervous | 0.81380201 |
122 | MP0001881_abnormal_mammary_gland | 0.81204554 |
123 | MP0002638_abnormal_pupillary_reflex | 0.79645384 |
124 | MP0001542_abnormal_bone_strength | 0.78864463 |
125 | MP0000465_gastrointestinal_hemorrhage | 0.78395545 |
126 | MP0003453_abnormal_keratinocyte_physiol | 0.77876848 |
127 | MP0000003_abnormal_adipose_tissue | 0.77433789 |
128 | MP0002419_abnormal_innate_immunity | 0.77022732 |
129 | MP0005330_cardiomyopathy | 0.76950853 |
130 | MP0000566_synostosis | 0.76942832 |
131 | MP0003172_abnormal_lysosome_physiology | 0.76297305 |
132 | MP0002019_abnormal_tumor_incidence | 0.76027882 |
133 | MP0005384_cellular_phenotype | 0.76026097 |
134 | MP0001145_abnormal_male_reproductive | 0.75719538 |
135 | MP0004742_abnormal_vestibular_system | 0.75506161 |
136 | MP0010155_abnormal_intestine_physiology | 0.74458774 |
137 | MP0002160_abnormal_reproductive_system | 0.74172930 |
138 | MP0002272_abnormal_nervous_system | 0.73970771 |
139 | MP0002405_respiratory_system_inflammati | 0.73206784 |
140 | MP0005670_abnormal_white_adipose | 0.71571503 |
141 | MP0003448_altered_tumor_morphology | 0.71470647 |
142 | MP0000358_abnormal_cell_content/ | 0.68990660 |
143 | MP0001730_embryonic_growth_arrest | 0.67641741 |
144 | MP0001968_abnormal_touch/_nociception | 0.67219911 |
145 | MP0004808_abnormal_hematopoietic_stem | 0.66888046 |
146 | MP0002277_abnormal_respiratory_mucosa | 0.66752626 |
147 | MP0003866_abnormal_defecation | 0.65478442 |
148 | MP0003950_abnormal_plasma_membrane | 0.64879579 |
149 | MP0003938_abnormal_ear_development | 0.64737675 |
150 | MP0000653_abnormal_sex_gland | 0.64481613 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.30623887 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 5.09129262 |
3 | Acute necrotizing encephalopathy (HP:0006965) | 5.05617823 |
4 | Mitochondrial inheritance (HP:0001427) | 4.94654210 |
5 | Hepatocellular necrosis (HP:0001404) | 4.58418481 |
6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.48924332 |
7 | Increased hepatocellular lipid droplets (HP:0006565) | 4.39373068 |
8 | 3-Methylglutaconic aciduria (HP:0003535) | 4.23017594 |
9 | Increased CSF lactate (HP:0002490) | 4.16485753 |
10 | Progressive macrocephaly (HP:0004481) | 4.03047585 |
11 | Cerebral hypomyelination (HP:0006808) | 3.96404740 |
12 | Ragged-red muscle fibers (HP:0003200) | 3.87177451 |
13 | Renal Fanconi syndrome (HP:0001994) | 3.82107139 |
14 | Acute encephalopathy (HP:0006846) | 3.81669280 |
15 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.81306053 |
16 | Hepatic necrosis (HP:0002605) | 3.80514145 |
17 | Reticulocytopenia (HP:0001896) | 3.77240581 |
18 | Lipid accumulation in hepatocytes (HP:0006561) | 3.73040115 |
19 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.69958101 |
20 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.69958101 |
21 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.62923053 |
22 | Abnormality of glycolysis (HP:0004366) | 3.59385071 |
23 | Increased serum pyruvate (HP:0003542) | 3.59385071 |
24 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.55705254 |
25 | Macrocytic anemia (HP:0001972) | 3.35508545 |
26 | Exertional dyspnea (HP:0002875) | 3.29725745 |
27 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.23418085 |
28 | Increased serum lactate (HP:0002151) | 3.22317484 |
29 | Birth length less than 3rd percentile (HP:0003561) | 3.15734325 |
30 | Increased intramyocellular lipid droplets (HP:0012240) | 3.00537896 |
31 | Progressive muscle weakness (HP:0003323) | 2.99975387 |
32 | Testicular atrophy (HP:0000029) | 2.99421189 |
33 | Type I transferrin isoform profile (HP:0003642) | 2.99278590 |
34 | Parakeratosis (HP:0001036) | 2.93584947 |
35 | Aplastic anemia (HP:0001915) | 2.91997762 |
36 | Pallor (HP:0000980) | 2.91525473 |
37 | Respiratory difficulties (HP:0002880) | 2.91307887 |
38 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.90983864 |
39 | Respiratory failure (HP:0002878) | 2.89408192 |
40 | Leukodystrophy (HP:0002415) | 2.87212869 |
41 | Exercise intolerance (HP:0003546) | 2.86616441 |
42 | Lactic acidosis (HP:0003128) | 2.70357695 |
43 | Broad distal phalanx of finger (HP:0009836) | 2.66605409 |
44 | Multiple enchondromatosis (HP:0005701) | 2.64712022 |
45 | Vertebral compression fractures (HP:0002953) | 2.60356750 |
46 | Breast hypoplasia (HP:0003187) | 2.55482875 |
47 | Myopathic facies (HP:0002058) | 2.46610223 |
48 | CNS hypomyelination (HP:0003429) | 2.45323232 |
49 | Achilles tendon contracture (HP:0001771) | 2.44522714 |
50 | Optic disc pallor (HP:0000543) | 2.41645730 |
51 | Hypertensive crisis (HP:0100735) | 2.39110393 |
52 | Abnormal gallbladder physiology (HP:0012438) | 2.36852508 |
53 | Cholecystitis (HP:0001082) | 2.36852508 |
54 | Rough bone trabeculation (HP:0100670) | 2.35670577 |
55 | Increased muscle lipid content (HP:0009058) | 2.34332331 |
56 | IgM deficiency (HP:0002850) | 2.34238749 |
57 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.32182204 |
58 | Microvesicular hepatic steatosis (HP:0001414) | 2.31558712 |
59 | Type 2 muscle fiber atrophy (HP:0003554) | 2.29786246 |
60 | Abnormality of renal resorption (HP:0011038) | 2.29556120 |
61 | Abnormality of the umbilical cord (HP:0010881) | 2.27553705 |
62 | Hypokinesia (HP:0002375) | 2.27404113 |
63 | Trismus (HP:0000211) | 2.27009911 |
64 | Prolonged neonatal jaundice (HP:0006579) | 2.26544133 |
65 | Oral leukoplakia (HP:0002745) | 2.25662442 |
66 | Abnormality of glycolipid metabolism (HP:0010969) | 2.25310488 |
67 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.25310488 |
68 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.25310488 |
69 | Increased cerebral lipofuscin (HP:0011813) | 2.23787404 |
70 | Cerebral edema (HP:0002181) | 2.20285366 |
71 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.18400173 |
72 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.17455756 |
73 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.16271279 |
74 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.16271279 |
75 | Abnormal protein glycosylation (HP:0012346) | 2.16271279 |
76 | Abnormal glycosylation (HP:0012345) | 2.16271279 |
77 | Muscle fiber atrophy (HP:0100295) | 2.13938514 |
78 | Increased serum ferritin (HP:0003281) | 2.11843192 |
79 | Obstructive lung disease (HP:0006536) | 2.09421175 |
80 | Chronic obstructive pulmonary disease (HP:0006510) | 2.09421175 |
81 | Carpal bone hypoplasia (HP:0001498) | 2.06895060 |
82 | CNS demyelination (HP:0007305) | 2.05821923 |
83 | Pancytopenia (HP:0001876) | 2.03970135 |
84 | Distal lower limb muscle weakness (HP:0009053) | 2.03778571 |
85 | Abnormality of the Achilles tendon (HP:0005109) | 2.03131327 |
86 | Emotional lability (HP:0000712) | 2.02462302 |
87 | Abnormality of reticulocytes (HP:0004312) | 1.98268499 |
88 | Petechiae (HP:0000967) | 1.97073344 |
89 | Patchy hypopigmentation of hair (HP:0011365) | 1.96657830 |
90 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.96416857 |
91 | Postnatal microcephaly (HP:0005484) | 1.95360722 |
92 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.94719767 |
93 | Dicarboxylic aciduria (HP:0003215) | 1.94719767 |
94 | Progressive neurologic deterioration (HP:0002344) | 1.93590145 |
95 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.92326111 |
96 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.92326111 |
97 | Single umbilical artery (HP:0001195) | 1.92326111 |
98 | Neuroendocrine neoplasm (HP:0100634) | 1.90228072 |
99 | Premature graying of hair (HP:0002216) | 1.89165925 |
100 | Increased IgM level (HP:0003496) | 1.89153647 |
101 | Sensory axonal neuropathy (HP:0003390) | 1.87402079 |
102 | Bulbar palsy (HP:0001283) | 1.87312118 |
103 | Recurrent abscess formation (HP:0002722) | 1.85266370 |
104 | Abnormal trabecular bone morphology (HP:0100671) | 1.84707507 |
105 | Asplenia (HP:0001746) | 1.84289915 |
106 | Poor head control (HP:0002421) | 1.83196556 |
107 | Fasciculations (HP:0002380) | 1.81831400 |
108 | Generalized amyotrophy (HP:0003700) | 1.80126702 |
109 | Medial flaring of the eyebrow (HP:0010747) | 1.79044960 |
110 | Recurrent bacterial skin infections (HP:0005406) | 1.78886080 |
111 | Opisthotonus (HP:0002179) | 1.78087901 |
112 | IgG deficiency (HP:0004315) | 1.77891043 |
113 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.77155540 |
114 | Rhabdomyolysis (HP:0003201) | 1.76194558 |
115 | Dysphonia (HP:0001618) | 1.75756556 |
116 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.74905423 |
117 | Cholelithiasis (HP:0001081) | 1.74866261 |
118 | Hepatosplenomegaly (HP:0001433) | 1.74663479 |
119 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.74005342 |
120 | Hyperparathyroidism (HP:0000843) | 1.73132143 |
121 | Death in infancy (HP:0001522) | 1.72952217 |
122 | Delusions (HP:0000746) | 1.72944691 |
123 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.70982170 |
124 | Duplicated collecting system (HP:0000081) | 1.70578392 |
125 | Cerebral palsy (HP:0100021) | 1.69949596 |
126 | Abnormality of macrophages (HP:0004311) | 1.69725313 |
127 | Microretrognathia (HP:0000308) | 1.69285028 |
128 | Hypergonadotropic hypogonadism (HP:0000815) | 1.68630445 |
129 | Hypoplastic pelvis (HP:0008839) | 1.65364700 |
130 | Bone marrow hypocellularity (HP:0005528) | 1.65032895 |
131 | Abnormality of the preputium (HP:0100587) | 1.64913026 |
132 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.64089562 |
133 | Abnormal lung lobation (HP:0002101) | 1.63115374 |
134 | Secondary amenorrhea (HP:0000869) | 1.61061464 |
135 | Absent epiphyses (HP:0010577) | 1.60333127 |
136 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.60333127 |
137 | Sparse eyelashes (HP:0000653) | 1.59968564 |
138 | Triphalangeal thumb (HP:0001199) | 1.58716238 |
139 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.56507722 |
140 | Thrombocytosis (HP:0001894) | 1.55330486 |
141 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.54963814 |
142 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.54963814 |
143 | Erythema (HP:0010783) | 1.54854901 |
144 | Spastic paraparesis (HP:0002313) | 1.54755417 |
145 | Abnormality of placental membranes (HP:0011409) | 1.54011729 |
146 | Amniotic constriction ring (HP:0009775) | 1.54011729 |
147 | Reduced antithrombin III activity (HP:0001976) | 1.53798000 |
148 | Irregular epiphyses (HP:0010582) | 1.52816622 |
149 | White forelock (HP:0002211) | 1.51478256 |
150 | Abnormality of urine glucose concentration (HP:0011016) | 1.50627555 |
151 | Glycosuria (HP:0003076) | 1.50627555 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.35379564 |
2 | VRK2 | 4.08166668 |
3 | STK16 | 3.73152540 |
4 | NME2 | 3.44636518 |
5 | SMG1 | 3.19490401 |
6 | VRK1 | 2.91485930 |
7 | IRAK3 | 2.83313428 |
8 | WEE1 | 2.77469198 |
9 | EIF2AK1 | 2.66057450 |
10 | TRIB3 | 2.50678447 |
11 | CDK19 | 2.41025375 |
12 | PBK | 2.29887031 |
13 | EIF2AK3 | 2.15924051 |
14 | PLK4 | 1.97681615 |
15 | TESK2 | 1.97509437 |
16 | PIM2 | 1.94543429 |
17 | STK39 | 1.87509509 |
18 | ERN1 | 1.85237591 |
19 | MAP3K12 | 1.84509563 |
20 | LIMK1 | 1.76405755 |
21 | TAOK2 | 1.75905892 |
22 | SCYL2 | 1.70643904 |
23 | TNIK | 1.68953502 |
24 | SRPK1 | 1.66038219 |
25 | TLK1 | 1.65926674 |
26 | OXSR1 | 1.62957435 |
27 | PRPF4B | 1.61676125 |
28 | MAPKAPK5 | 1.59885666 |
29 | ARAF | 1.54339792 |
30 | NME1 | 1.51386145 |
31 | MST4 | 1.46428632 |
32 | TSSK6 | 1.43720831 |
33 | MAP2K3 | 1.40074750 |
34 | MUSK | 1.39056646 |
35 | MKNK1 | 1.36006189 |
36 | DYRK3 | 1.34292216 |
37 | CCNB1 | 1.32076608 |
38 | KDR | 1.30108532 |
39 | BRSK2 | 1.29332648 |
40 | DYRK2 | 1.28740491 |
41 | CDC7 | 1.28285837 |
42 | PAK4 | 1.27888224 |
43 | NEK1 | 1.21834310 |
44 | CLK1 | 1.19102832 |
45 | TBK1 | 1.17638444 |
46 | BCR | 1.16083703 |
47 | ACVR1B | 1.14136270 |
48 | IRAK4 | 1.13296971 |
49 | MAP4K1 | 1.12487454 |
50 | CSNK1G3 | 1.05286537 |
51 | CASK | 1.04544233 |
52 | DAPK1 | 1.02871683 |
53 | KIT | 1.02647022 |
54 | TXK | 1.01902405 |
55 | AURKA | 1.00807117 |
56 | MYLK | 0.99971659 |
57 | MAP3K8 | 0.98221124 |
58 | BRAF | 0.97573619 |
59 | PRKD3 | 0.97074211 |
60 | TESK1 | 0.97024202 |
61 | DAPK3 | 0.92575290 |
62 | BRSK1 | 0.92079561 |
63 | CDK8 | 0.91867911 |
64 | PLK1 | 0.89799467 |
65 | ABL2 | 0.87757639 |
66 | ILK | 0.87276973 |
67 | BLK | 0.86684835 |
68 | RPS6KA5 | 0.84730572 |
69 | ADRBK2 | 0.82240061 |
70 | ZAK | 0.81871081 |
71 | SIK1 | 0.81400450 |
72 | EPHA2 | 0.80730913 |
73 | TAOK1 | 0.79620762 |
74 | IRAK2 | 0.78000140 |
75 | TEC | 0.77147373 |
76 | AURKB | 0.76954003 |
77 | PRKCI | 0.76699405 |
78 | PAK1 | 0.76495105 |
79 | PLK3 | 0.74353678 |
80 | MAP3K3 | 0.74153905 |
81 | GRK6 | 0.70562606 |
82 | ICK | 0.69054859 |
83 | TYK2 | 0.68756183 |
84 | MAPK13 | 0.68526166 |
85 | UHMK1 | 0.68427513 |
86 | LYN | 0.64731775 |
87 | CSNK2A1 | 0.63942957 |
88 | MAP2K2 | 0.61998159 |
89 | GRK7 | 0.61608787 |
90 | CDK4 | 0.61301708 |
91 | BTK | 0.60894965 |
92 | SYK | 0.60827118 |
93 | BMPR1B | 0.60269660 |
94 | EIF2AK2 | 0.60255022 |
95 | TAF1 | 0.60209639 |
96 | TRPM7 | 0.59351428 |
97 | PRKD2 | 0.58823948 |
98 | EEF2K | 0.58595409 |
99 | STK4 | 0.58469713 |
100 | CDK7 | 0.57004813 |
101 | CSNK2A2 | 0.54081018 |
102 | CSNK1G1 | 0.53905265 |
103 | CSF1R | 0.53424283 |
104 | YES1 | 0.53004943 |
105 | PKN1 | 0.52617730 |
106 | STK10 | 0.51810933 |
107 | CAMK2B | 0.51554284 |
108 | BMX | 0.51203824 |
109 | MAP3K11 | 0.50924568 |
110 | CDK9 | 0.50257882 |
111 | RPS6KB2 | 0.48793945 |
112 | MAPKAPK3 | 0.48632901 |
113 | AKT2 | 0.47760220 |
114 | NEK2 | 0.47464004 |
115 | BCKDK | 0.47320290 |
116 | MKNK2 | 0.47022777 |
117 | MAPK11 | 0.47005437 |
118 | MAP3K10 | 0.46891803 |
119 | MAP3K1 | 0.46579148 |
120 | CHEK2 | 0.46394444 |
121 | CDK14 | 0.45787251 |
122 | TTK | 0.45528524 |
123 | CDK11A | 0.45442279 |
124 | CSNK1A1L | 0.45030616 |
125 | TTN | 0.43206044 |
126 | CDK18 | 0.43127188 |
127 | IKBKB | 0.42875135 |
128 | RPS6KC1 | 0.42178526 |
129 | RPS6KL1 | 0.42178526 |
130 | GRK5 | 0.41642638 |
131 | CDK3 | 0.41598682 |
132 | CDK15 | 0.41578166 |
133 | LCK | 0.41380032 |
134 | PNCK | 0.41152885 |
135 | RAF1 | 0.41148587 |
136 | ATR | 0.40609074 |
137 | PDK2 | 0.40192342 |
138 | ROCK2 | 0.37734257 |
139 | CSNK1G2 | 0.36691812 |
140 | RIPK4 | 0.35450033 |
141 | FES | 0.35196152 |
142 | TNK2 | 0.34138189 |
143 | NEK6 | 0.34042980 |
144 | LRRK2 | 0.33376859 |
145 | ZAP70 | 0.33226329 |
146 | PRKG2 | 0.33138859 |
147 | RPS6KA4 | 0.32816156 |
148 | CAMK2G | 0.32809615 |
149 | CHEK1 | 0.32237040 |
150 | PIM1 | 0.31960525 |
151 | PTK6 | 0.31783780 |
152 | PDPK1 | 0.30664780 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 4.85392408 |
2 | Proteasome_Homo sapiens_hsa03050 | 4.60636437 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 3.73961027 |
4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.73578349 |
5 | DNA replication_Homo sapiens_hsa03030 | 3.48419889 |
6 | Parkinsons disease_Homo sapiens_hsa05012 | 3.25351476 |
7 | Protein export_Homo sapiens_hsa03060 | 2.89855475 |
8 | Mismatch repair_Homo sapiens_hsa03430 | 2.80370542 |
9 | Spliceosome_Homo sapiens_hsa03040 | 2.46483355 |
10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.45754382 |
11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.41741693 |
12 | Homologous recombination_Homo sapiens_hsa03440 | 2.39110332 |
13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.34221461 |
14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.28412833 |
15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.13507164 |
16 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.09855770 |
17 | Base excision repair_Homo sapiens_hsa03410 | 2.09444185 |
18 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.99224016 |
19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.93452588 |
20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.88409627 |
21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.84354544 |
22 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.72686660 |
23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.67961635 |
24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.66768530 |
25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.55293773 |
26 | RNA transport_Homo sapiens_hsa03013 | 1.54492321 |
27 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.47208231 |
28 | RNA degradation_Homo sapiens_hsa03018 | 1.42847985 |
29 | Carbon metabolism_Homo sapiens_hsa01200 | 1.41448868 |
30 | Purine metabolism_Homo sapiens_hsa00230 | 1.40665051 |
31 | Galactose metabolism_Homo sapiens_hsa00052 | 1.38479818 |
32 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.37408668 |
33 | Cell cycle_Homo sapiens_hsa04110 | 1.35833430 |
34 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.25633950 |
35 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.19759818 |
36 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.18863264 |
37 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.04331112 |
38 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.04109726 |
39 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.98905825 |
40 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.96545673 |
41 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.96180636 |
42 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.94976821 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.91905721 |
44 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.91599854 |
45 | Bladder cancer_Homo sapiens_hsa05219 | 0.86822694 |
46 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.85587616 |
47 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.85123801 |
48 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.85089080 |
49 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.82863347 |
50 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.82350559 |
51 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.81575871 |
52 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.80703464 |
53 | Lysosome_Homo sapiens_hsa04142 | 0.80488581 |
54 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.76185589 |
55 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.72695781 |
56 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.70939001 |
57 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.69723084 |
58 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.69579763 |
59 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.69511157 |
60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.67269297 |
61 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.66711516 |
62 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.65008280 |
63 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.62662977 |
64 | Asthma_Homo sapiens_hsa05310 | 0.61997095 |
65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61499487 |
66 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.61390172 |
67 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.60766616 |
68 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.60689998 |
69 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.57990357 |
70 | Allograft rejection_Homo sapiens_hsa05330 | 0.57275357 |
71 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.57073168 |
72 | HTLV-I infection_Homo sapiens_hsa05166 | 0.56813416 |
73 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.56307457 |
74 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.52753859 |
75 | Shigellosis_Homo sapiens_hsa05131 | 0.52720592 |
76 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.52373368 |
77 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.51982372 |
78 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.51286498 |
79 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.50714542 |
80 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.49318363 |
81 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.48934069 |
82 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.47526287 |
83 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.46539568 |
84 | Sulfur relay system_Homo sapiens_hsa04122 | 0.45065703 |
85 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.44275531 |
86 | Viral myocarditis_Homo sapiens_hsa05416 | 0.43370865 |
87 | Prion diseases_Homo sapiens_hsa05020 | 0.41779607 |
88 | Phagosome_Homo sapiens_hsa04145 | 0.40707825 |
89 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.40382431 |
90 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.40101271 |
91 | Alcoholism_Homo sapiens_hsa05034 | 0.38912090 |
92 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.38899044 |
93 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.37176843 |
94 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.36899719 |
95 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.36266365 |
96 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.35778886 |
97 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.35621882 |
98 | Peroxisome_Homo sapiens_hsa04146 | 0.35184497 |
99 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.34567780 |
100 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.33066025 |
101 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.31766819 |
102 | Endocytosis_Homo sapiens_hsa04144 | 0.31671294 |
103 | Leishmaniasis_Homo sapiens_hsa05140 | 0.30491303 |
104 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.28923650 |
105 | Tuberculosis_Homo sapiens_hsa05152 | 0.28892725 |
106 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.28055701 |
107 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.27730628 |
108 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.26890431 |
109 | Measles_Homo sapiens_hsa05162 | 0.24679352 |
110 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.23156106 |
111 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.22772396 |
112 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.21979683 |
113 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.21420196 |
114 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.20834209 |
115 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.20310397 |
116 | Legionellosis_Homo sapiens_hsa05134 | 0.19417407 |
117 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.18681859 |
118 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.18073821 |
119 | Pertussis_Homo sapiens_hsa05133 | 0.17426948 |
120 | Phototransduction_Homo sapiens_hsa04744 | 0.16717728 |
121 | Malaria_Homo sapiens_hsa05144 | 0.16710077 |
122 | Other glycan degradation_Homo sapiens_hsa00511 | 0.16559929 |
123 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.14415682 |
124 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.13417045 |
125 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.13048049 |
126 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.11789432 |
127 | Salmonella infection_Homo sapiens_hsa05132 | 0.11485382 |
128 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.11471836 |
129 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.09488834 |
130 | Apoptosis_Homo sapiens_hsa04210 | 0.07897968 |
131 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.06681423 |
132 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.05959300 |
133 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.05921716 |
134 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.05061065 |
135 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.04966413 |