SSSCA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.83395068
2maturation of SSU-rRNA (GO:0030490)5.33989654
3viral transcription (GO:0019083)5.22855819
4translational termination (GO:0006415)5.11341004
5ribosomal small subunit assembly (GO:0000028)5.01648183
6ribosomal small subunit biogenesis (GO:0042274)4.97637257
7proteasome assembly (GO:0043248)4.97096840
8respiratory electron transport chain (GO:0022904)4.91030849
9mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.87509164
10ribosomal large subunit biogenesis (GO:0042273)4.83060003
11electron transport chain (GO:0022900)4.81859667
12spliceosomal snRNP assembly (GO:0000387)4.63480745
13translational elongation (GO:0006414)4.60603962
14formation of translation preinitiation complex (GO:0001731)4.52970779
15transcription elongation from RNA polymerase III promoter (GO:0006385)4.50156128
16termination of RNA polymerase III transcription (GO:0006386)4.50156128
17translational initiation (GO:0006413)4.49342929
18ribonucleoprotein complex biogenesis (GO:0022613)4.41416112
19SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.34702000
20protein complex biogenesis (GO:0070271)4.31402772
21cotranslational protein targeting to membrane (GO:0006613)4.28206627
22protein targeting to ER (GO:0045047)4.24849454
23mitochondrial respiratory chain complex assembly (GO:0033108)4.19677354
24DNA strand elongation involved in DNA replication (GO:0006271)4.16191516
25cellular protein complex disassembly (GO:0043624)4.15645082
26pseudouridine synthesis (GO:0001522)4.14411960
27negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.13658643
28ribosome biogenesis (GO:0042254)4.12658062
29nucleobase biosynthetic process (GO:0046112)4.10084444
30mitochondrial respiratory chain complex I assembly (GO:0032981)4.09600543
31NADH dehydrogenase complex assembly (GO:0010257)4.09600543
32mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.09600543
33nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.08581938
34spliceosomal complex assembly (GO:0000245)4.05263680
35viral life cycle (GO:0019058)4.03840837
36purine nucleobase biosynthetic process (GO:0009113)4.03223169
37establishment of protein localization to endoplasmic reticulum (GO:0072599)4.02378502
38protein localization to endoplasmic reticulum (GO:0070972)4.01682759
39establishment of integrated proviral latency (GO:0075713)3.98684935
40rRNA processing (GO:0006364)3.97836784
41protein maturation by protein folding (GO:0022417)3.96658505
42translation (GO:0006412)3.95758181
437-methylguanosine mRNA capping (GO:0006370)3.95009130
44DNA strand elongation (GO:0022616)3.93927648
45telomere maintenance via semi-conservative replication (GO:0032201)3.92821521
46positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.91065845
47deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.90525477
48pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.89890448
49DNA replication initiation (GO:0006270)3.88824125
50rRNA modification (GO:0000154)3.87693086
51anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.86913292
52regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.86543028
53RNA capping (GO:0036260)3.86079362
547-methylguanosine RNA capping (GO:0009452)3.86079362
55protein neddylation (GO:0045116)3.83655997
56rRNA metabolic process (GO:0016072)3.83181574
57negative regulation of ligase activity (GO:0051352)3.83016993
58negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.83016993
59establishment of protein localization to mitochondrial membrane (GO:0090151)3.78520952
60mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.77879090
61cellular component biogenesis (GO:0044085)3.76617798
62protein complex disassembly (GO:0043241)3.73943648
63ribosome assembly (GO:0042255)3.70479668
64regulation of mitochondrial translation (GO:0070129)3.66545777
65macromolecular complex disassembly (GO:0032984)3.59653317
66chaperone-mediated protein transport (GO:0072321)3.59261514
67DNA replication checkpoint (GO:0000076)3.58592429
68transcription-coupled nucleotide-excision repair (GO:0006283)3.58523850
69purine nucleoside triphosphate biosynthetic process (GO:0009145)3.56088811
70pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.55614956
71purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.54627512
72CTP biosynthetic process (GO:0006241)3.54363433
73CTP metabolic process (GO:0046036)3.54363433
74guanosine-containing compound biosynthetic process (GO:1901070)3.54274682
75cullin deneddylation (GO:0010388)3.52702280
76exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.50962245
77inner mitochondrial membrane organization (GO:0007007)3.50759647
78L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.50730557
79RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.49765887
80tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.49765887
81viral mRNA export from host cell nucleus (GO:0046784)3.49542265
82regulation of cellular amino acid metabolic process (GO:0006521)3.46705891
83DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.46484321
84transcription from RNA polymerase I promoter (GO:0006360)3.46154584
85transcription elongation from RNA polymerase I promoter (GO:0006362)3.45620650
86ATP synthesis coupled proton transport (GO:0015986)3.45520868
87energy coupled proton transport, down electrochemical gradient (GO:0015985)3.45520868
88positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.44952706
89UTP metabolic process (GO:0046051)3.44586123
90pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.43474351
91termination of RNA polymerase I transcription (GO:0006363)3.43221506
92antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.42253319
93nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.41198383
94intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.40360745
95signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.40360745
96establishment of protein localization to mitochondrion (GO:0072655)3.39456671
97signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.39376633
98signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.39376633
99signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.39376633
100GTP biosynthetic process (GO:0006183)3.37962289
101mitochondrial transport (GO:0006839)3.37058172
102CENP-A containing nucleosome assembly (GO:0034080)3.36662638
103pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.36263005
104protein targeting to mitochondrion (GO:0006626)3.35427339
105signal transduction involved in DNA damage checkpoint (GO:0072422)3.34446713
106signal transduction involved in DNA integrity checkpoint (GO:0072401)3.34446713
107telomere maintenance via recombination (GO:0000722)3.34440577
108ribonucleoside triphosphate biosynthetic process (GO:0009201)3.34435896
109UTP biosynthetic process (GO:0006228)3.34402014
110protein deneddylation (GO:0000338)3.33917573
111ATP biosynthetic process (GO:0006754)3.33570424
112base-excision repair, AP site formation (GO:0006285)3.32996255
113signal transduction involved in cell cycle checkpoint (GO:0072395)3.31646430
114oxidative phosphorylation (GO:0006119)3.30732663
115positive regulation of ligase activity (GO:0051351)3.29720964
116respiratory chain complex IV assembly (GO:0008535)3.28405942
117protein targeting to membrane (GO:0006612)3.28243849
118nuclear-transcribed mRNA catabolic process (GO:0000956)3.26235134
119cytochrome complex assembly (GO:0017004)3.25135287
120chromatin remodeling at centromere (GO:0031055)3.24311135
121peptidyl-histidine modification (GO:0018202)3.23149809
122pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.22845797
123DNA unwinding involved in DNA replication (GO:0006268)3.20764525
124mitotic metaphase plate congression (GO:0007080)3.19594679
125telomere maintenance via telomere lengthening (GO:0010833)3.12858838
126regulation of ubiquitin-protein transferase activity (GO:0051438)3.12427561
127establishment of viral latency (GO:0019043)3.11942275
128ncRNA processing (GO:0034470)3.10940535
129histone arginine methylation (GO:0034969)3.10541832
130peptidyl-arginine omega-N-methylation (GO:0035247)3.10319647
131protein localization to mitochondrion (GO:0070585)3.07854477
132DNA-templated transcription, termination (GO:0006353)3.07450570
133ncRNA metabolic process (GO:0034660)3.06781405

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.36292998
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.71160117
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.12174260
4* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.04038188
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.85705943
6* GABP_17652178_ChIP-ChIP_JURKAT_Human3.76181242
7* ETS1_20019798_ChIP-Seq_JURKAT_Human3.68880067
8* EST1_17652178_ChIP-ChIP_JURKAT_Human3.68734439
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.36223314
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.29981806
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.29088073
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.28184826
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.27688970
14* CREB1_15753290_ChIP-ChIP_HEK293T_Human3.18883588
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.09106244
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.88306400
17E2F4_17652178_ChIP-ChIP_JURKAT_Human2.75038873
18* XRN2_22483619_ChIP-Seq_HELA_Human2.72193513
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.66763880
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.66426109
21THAP11_20581084_ChIP-Seq_MESCs_Mouse2.51341809
22VDR_23849224_ChIP-Seq_CD4+_Human2.48731029
23* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.43035920
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.37263243
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.32153464
26DCP1A_22483619_ChIP-Seq_HELA_Human2.29014263
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.28469641
28ELF1_17652178_ChIP-ChIP_JURKAT_Human2.25591522
29FOXM1_23109430_ChIP-Seq_U2OS_Human2.21008355
30YY1_21170310_ChIP-Seq_MESCs_Mouse2.20387178
31* GABP_19822575_ChIP-Seq_HepG2_Human2.16298015
32TTF2_22483619_ChIP-Seq_HELA_Human2.14744455
33FOXP3_21729870_ChIP-Seq_TREG_Human2.12855234
34MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.11125004
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.91807240
36ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.91412139
37SRF_21415370_ChIP-Seq_HL-1_Mouse1.83917418
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.83805354
39MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79312069
40NANOG_18555785_ChIP-Seq_MESCs_Mouse1.73497789
41YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.70455930
42ZNF263_19887448_ChIP-Seq_K562_Human1.69063459
43PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.63323271
44CIITA_25753668_ChIP-Seq_RAJI_Human1.62154651
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.61431217
46ELK1_19687146_ChIP-ChIP_HELA_Human1.56803590
47TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.55708779
48TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.54253490
49PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.53767065
50CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.52642557
51* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.52268989
52CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.51825232
53ZFX_18555785_ChIP-Seq_MESCs_Mouse1.50784133
54CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.48616616
55* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.46547576
56MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.44619870
57* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.41758857
58CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.40929252
59* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.34326725
60PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.33966478
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.33481789
62AR_21909140_ChIP-Seq_LNCAP_Human1.32176934
63E2F1_21310950_ChIP-Seq_MCF-7_Human1.31832129
64KDM5A_27292631_Chip-Seq_BREAST_Human1.28505834
65* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27528320
66POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.27472447
67SOX2_18555785_ChIP-Seq_MESCs_Mouse1.24711798
68ELK1_22589737_ChIP-Seq_MCF10A_Human1.23476442
69MYC_18940864_ChIP-ChIP_HL60_Human1.21634386
70* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.21540779
71BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.18391186
72SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.17804277
73* TET1_21451524_ChIP-Seq_MESCs_Mouse1.16776625
74ERG_20887958_ChIP-Seq_HPC-7_Mouse1.15336509
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13933907
76SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.13856737
77CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.13647887
78NOTCH1_21737748_ChIP-Seq_TLL_Human1.13469884
79SRY_22984422_ChIP-ChIP_TESTIS_Rat1.12638958
80VDR_21846776_ChIP-Seq_THP-1_Human1.12449253
81ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.12407876
82RBPJ_22232070_ChIP-Seq_NCS_Mouse1.11378995
83SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09803994
84CTCF_18555785_ChIP-Seq_MESCs_Mouse1.04980949
85KLF4_18555785_ChIP-Seq_MESCs_Mouse1.04255855
86ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.03600482
87YY1_22570637_ChIP-Seq_MALME-3M_Human1.03535351
88HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.02838663
89KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01147939
90E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99926811
91STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98704873
92DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.98408121
93OCT4_18692474_ChIP-Seq_MEFs_Mouse0.97092375
94* PADI4_21655091_ChIP-ChIP_MCF-7_Human0.97055968
95FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.95519395
96CTCF_26484167_Chip-Seq_Bcells_Mouse0.94780720
97ELF1_20517297_ChIP-Seq_JURKAT_Human0.93711949
98BP1_19119308_ChIP-ChIP_Hs578T_Human0.93113978
99* FOXP1_21924763_ChIP-Seq_HESCs_Human0.91776295
100SOX2_18692474_ChIP-Seq_MEFs_Mouse0.91589835
101HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.90906048
102TBX5_21415370_ChIP-Seq_HL-1_Mouse0.90375650
103* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.89685635
104* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.86258022
105* SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.85973126
106TP63_19390658_ChIP-ChIP_HaCaT_Human0.85938656
107BCL6_27268052_Chip-Seq_Bcells_Human0.85631136
108ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.85184416
109KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.83945392
110SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.83927794
111EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.82234782
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82141252
113* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.80923076
114TFEB_21752829_ChIP-Seq_HELA_Human0.80237805
115GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79458105
116TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.79451727
117* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78992063
118NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.78722237
119* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.78486037

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.61439520
2MP0004957_abnormal_blastocyst_morpholog4.18910384
3MP0003111_abnormal_nucleus_morphology4.06657707
4MP0010094_abnormal_chromosome_stability3.64886952
5MP0003077_abnormal_cell_cycle3.60604461
6MP0008058_abnormal_DNA_repair3.33961247
7MP0008932_abnormal_embryonic_tissue3.17481369
8MP0009379_abnormal_foot_pigmentation2.80526603
9MP0006292_abnormal_olfactory_placode2.66295725
10MP0008057_abnormal_DNA_replication2.44360879
11MP0003718_maternal_effect2.43721750
12MP0008007_abnormal_cellular_replicative2.36195122
13MP0002837_dystrophic_cardiac_calcinosis2.27035764
14MP0003315_abnormal_perineum_morphology2.25841415
15MP0000372_irregular_coat_pigmentation2.24828227
16MP0003123_paternal_imprinting2.24771212
17MP0003786_premature_aging2.22596820
18MP0001853_heart_inflammation2.18899743
19MP0004133_heterotaxia2.12848925
20MP0001730_embryonic_growth_arrest2.04473155
21MP0001529_abnormal_vocalization2.01175311
22MP0005670_abnormal_white_adipose1.90232052
23MP0010030_abnormal_orbit_morphology1.90060698
24MP0002277_abnormal_respiratory_mucosa1.89041476
25MP0008877_abnormal_DNA_methylation1.84958179
26MP0000350_abnormal_cell_proliferation1.77807552
27MP0002160_abnormal_reproductive_system1.72739095
28MP0006035_abnormal_mitochondrial_morpho1.70071417
29MP0002653_abnormal_ependyma_morphology1.66186888
30MP0002102_abnormal_ear_morphology1.62491903
31MP0008789_abnormal_olfactory_epithelium1.55824177
32MP0006036_abnormal_mitochondrial_physio1.48663659
33MP0003806_abnormal_nucleotide_metabolis1.48211812
34MP0001697_abnormal_embryo_size1.44664220
35MP0002751_abnormal_autonomic_nervous1.41090870
36MP0002080_prenatal_lethality1.38799934
37MP0000313_abnormal_cell_death1.35448454
38MP0002148_abnormal_hypersensitivity_rea1.33144918
39MP0002085_abnormal_embryonic_tissue1.32834406
40MP0002396_abnormal_hematopoietic_system1.29076788
41MP0005380_embryogenesis_phenotype1.28339706
42MP0001672_abnormal_embryogenesis/_devel1.28339706
43MP0001764_abnormal_homeostasis1.27742737
44MP0001881_abnormal_mammary_gland1.25176731
45MP0002210_abnormal_sex_determination1.24369675
46MP0002938_white_spotting1.23215721
47MP0000049_abnormal_middle_ear1.22681570
48MP0000358_abnormal_cell_content/1.22073035
49MP0005389_reproductive_system_phenotype1.20676848
50MP0005499_abnormal_olfactory_system1.19524284
51MP0005394_taste/olfaction_phenotype1.19524284
52MP0001905_abnormal_dopamine_level1.19515457
53MP0001293_anophthalmia1.18384268
54MP0003646_muscle_fatigue1.18135724
55MP0003186_abnormal_redox_activity1.16746662
56MP0005379_endocrine/exocrine_gland_phen1.16434985
57MP0008260_abnormal_autophagy1.16234263
58MP0003119_abnormal_digestive_system1.15152478
59MP0000678_abnormal_parathyroid_gland1.13767276
60MP0009333_abnormal_splenocyte_physiolog1.11790126
61MP0003941_abnormal_skin_development1.10398260
62MP0001145_abnormal_male_reproductive1.09564853
63MP0002132_abnormal_respiratory_system1.09380699
64MP0003984_embryonic_growth_retardation1.05379981
65MP0005501_abnormal_skin_physiology1.04546719
66MP0001835_abnormal_antigen_presentation1.03752301
67MP0003938_abnormal_ear_development1.02885723
68MP0005451_abnormal_body_composition1.02765478
69MP0002088_abnormal_embryonic_growth/wei1.02738907
70MP0005423_abnormal_somatic_nervous1.00878182
71MP0000685_abnormal_immune_system1.00571748
72MP0003136_yellow_coat_color1.00438243
73MP0003121_genomic_imprinting0.98960441
74MP0008872_abnormal_physiological_respon0.98953064
75MP0005084_abnormal_gallbladder_morpholo0.98692183
76MP0002084_abnormal_developmental_patter0.98047337
77MP0000750_abnormal_muscle_regeneration0.97871132
78MP0000343_altered_response_to0.96849377
79MP0001929_abnormal_gametogenesis0.95902788
80MP0005332_abnormal_amino_acid0.95256295
81MP0002019_abnormal_tumor_incidence0.93520481
82MP0004142_abnormal_muscle_tone0.92446473
83MP0004185_abnormal_adipocyte_glucose0.92286132
84MP0001873_stomach_inflammation0.91717170
85MP0003890_abnormal_embryonic-extraembry0.90923685
86MP0004858_abnormal_nervous_system0.90426775
87MP0000653_abnormal_sex_gland0.90392983
88MP0001986_abnormal_taste_sensitivity0.90365204
89MP0000490_abnormal_crypts_of0.90285322
90MP0003567_abnormal_fetal_cardiomyocyte0.89548484
91MP0000749_muscle_degeneration0.88368320
92MP0005075_abnormal_melanosome_morpholog0.87847068
93MP0003861_abnormal_nervous_system0.86807911
94MP0009697_abnormal_copulation0.86806007
95MP0001727_abnormal_embryo_implantation0.86509053
96MP0004147_increased_porphyrin_level0.86162228
97MP0002736_abnormal_nociception_after0.86077195
98MP0002638_abnormal_pupillary_reflex0.81827769
99MP0008875_abnormal_xenobiotic_pharmacok0.81149943
100MP0001188_hyperpigmentation0.80780517
101MP0006072_abnormal_retinal_apoptosis0.80557012
102MP0005671_abnormal_response_to0.80410224
103MP0000537_abnormal_urethra_morphology0.79561079
104MP0006276_abnormal_autonomic_nervous0.79259564
105MP0008873_increased_physiological_sensi0.78677025
106MP0001919_abnormal_reproductive_system0.77919809
107MP0001286_abnormal_eye_development0.75167814
108MP0009785_altered_susceptibility_to0.75040601
109MP0000689_abnormal_spleen_morphology0.72435755
110MP0005636_abnormal_mineral_homeostasis0.72137103
111MP0005410_abnormal_fertilization0.71743028
112MP0009672_abnormal_birth_weight0.71689829
113MP0005330_cardiomyopathy0.71402411
114MP0008995_early_reproductive_senescence0.71400916
115MP0004197_abnormal_fetal_growth/weight/0.71091618
116MP0003937_abnormal_limbs/digits/tail_de0.70157178
117MP0005266_abnormal_metabolism0.69716420
118MP0002722_abnormal_immune_system0.69474373
119MP0002429_abnormal_blood_cell0.69396633
120MP0003942_abnormal_urinary_system0.69337784
121MP0003698_abnormal_male_reproductive0.68897920
122MP0002398_abnormal_bone_marrow0.68119814
123MP0000428_abnormal_craniofacial_morphol0.67233387
124MP0002796_impaired_skin_barrier0.67058849
125MP0009250_abnormal_appendicular_skeleto0.66781406
126MP0002111_abnormal_tail_morphology0.66249307
127MP0003436_decreased_susceptibility_to0.65540451
128MP0000703_abnormal_thymus_morphology0.65264787
129MP0003656_abnormal_erythrocyte_physiolo0.65187022
130MP0004145_abnormal_muscle_electrophysio0.64571433
131MP0001542_abnormal_bone_strength0.64571279
132MP0003011_delayed_dark_adaptation0.64287048
133MP0003137_abnormal_impulse_conducting0.61932664
134MP0003763_abnormal_thymus_physiology0.61699909
135MP0001485_abnormal_pinna_reflex0.61653980
136MP0002086_abnormal_extraembryonic_tissu0.61506879
137MP0005319_abnormal_enzyme/_coenzyme0.59433261
138MP0000566_synostosis0.58785921
139MP0003880_abnormal_central_pattern0.57868603
140MP0004510_myositis0.57841632
141MP0002752_abnormal_somatic_nervous0.57234479
142MP0002114_abnormal_axial_skeleton0.55968652
143MP0009053_abnormal_anal_canal0.55773325
144MP0005384_cellular_phenotype0.55568284
145MP0002163_abnormal_gland_morphology0.55177361
146MP0002184_abnormal_innervation0.54278906

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.28376759
2Abnormal number of erythroid precursors (HP:0012131)5.02586069
3Cerebral hypomyelination (HP:0006808)4.70408176
4Reticulocytopenia (HP:0001896)4.51769028
5Acute necrotizing encephalopathy (HP:0006965)4.33133324
6Birth length less than 3rd percentile (HP:0003561)4.19625309
7Breast hypoplasia (HP:0003187)3.97453834
8Mitochondrial inheritance (HP:0001427)3.94873274
9Abnormal mitochondria in muscle tissue (HP:0008316)3.87914166
10Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.83026153
11Decreased activity of mitochondrial respiratory chain (HP:0008972)3.83026153
12Macrocytic anemia (HP:0001972)3.80211702
13Hepatocellular necrosis (HP:0001404)3.67393817
14Oral leukoplakia (HP:0002745)3.65676178
15Increased muscle lipid content (HP:0009058)3.62238207
16Increased CSF lactate (HP:0002490)3.43399851
17Progressive macrocephaly (HP:0004481)3.40320298
18Pallor (HP:0000980)3.34380609
193-Methylglutaconic aciduria (HP:0003535)3.32113329
20Rough bone trabeculation (HP:0100670)3.31136093
21Acute encephalopathy (HP:0006846)3.28717751
22Increased serum lactate (HP:0002151)3.18172318
23Aplastic anemia (HP:0001915)3.16659973
24Increased hepatocellular lipid droplets (HP:0006565)3.16024038
25Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.15679373
26Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.10346195
27Carpal bone hypoplasia (HP:0001498)3.09553747
28Increased serum pyruvate (HP:0003542)2.95961917
29Abnormality of glycolysis (HP:0004366)2.95961917
30Patellar aplasia (HP:0006443)2.90955839
31Colon cancer (HP:0003003)2.88386485
32Aplasia/Hypoplasia of the sacrum (HP:0008517)2.88079157
33Hepatic necrosis (HP:0002605)2.84764110
34Aplasia/Hypoplasia of the patella (HP:0006498)2.82879784
35Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.79336861
36Abnormal protein N-linked glycosylation (HP:0012347)2.79336861
37Abnormal protein glycosylation (HP:0012346)2.79336861
38Abnormal glycosylation (HP:0012345)2.79336861
39Trismus (HP:0000211)2.79103171
40Degeneration of anterior horn cells (HP:0002398)2.69106488
41Abnormality of the anterior horn cell (HP:0006802)2.69106488
42Exercise intolerance (HP:0003546)2.67683104
43Testicular atrophy (HP:0000029)2.67428344
44Lipid accumulation in hepatocytes (HP:0006561)2.64811349
45Lethargy (HP:0001254)2.64390480
46Secondary amenorrhea (HP:0000869)2.64353567
47Methylmalonic aciduria (HP:0012120)2.62503676
48CNS hypomyelination (HP:0003429)2.61380672
49Horseshoe kidney (HP:0000085)2.55968530
50Microvesicular hepatic steatosis (HP:0001414)2.51991598
51Absent thumb (HP:0009777)2.50604310
52Microretrognathia (HP:0000308)2.50023563
53Lactic acidosis (HP:0003128)2.49246341
54Respiratory failure (HP:0002878)2.49180118
55Premature ovarian failure (HP:0008209)2.43690263
56Supernumerary spleens (HP:0009799)2.41086977
57Absent radius (HP:0003974)2.40064517
58Premature graying of hair (HP:0002216)2.39917659
59Emotional lability (HP:0000712)2.39398900
60Delusions (HP:0000746)2.38350484
61Generalized aminoaciduria (HP:0002909)2.37403617
62Methylmalonic acidemia (HP:0002912)2.35926330
63Dicarboxylic aciduria (HP:0003215)2.35760015
64Abnormality of dicarboxylic acid metabolism (HP:0010995)2.35760015
65Selective tooth agenesis (HP:0001592)2.35236134
66Cellular immunodeficiency (HP:0005374)2.34815453
67Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.34769202
68Abnormal number of incisors (HP:0011064)2.32384206
69Renal Fanconi syndrome (HP:0001994)2.31931775
70Abnormality of renal resorption (HP:0011038)2.31551983
71Multiple enchondromatosis (HP:0005701)2.30384139
72Abnormal trabecular bone morphology (HP:0100671)2.28757464
73Reduced antithrombin III activity (HP:0001976)2.28123621
74Aplasia involving forearm bones (HP:0009822)2.26759124
75Absent forearm bone (HP:0003953)2.26759124
76Exertional dyspnea (HP:0002875)2.25852101
77Unsteady gait (HP:0002317)2.25174548
78Leukodystrophy (HP:0002415)2.24699399
79Triphalangeal thumb (HP:0001199)2.22090820
80Progressive microcephaly (HP:0000253)2.20406570
81Abnormality of the labia minora (HP:0012880)2.19967309
82Cleft eyelid (HP:0000625)2.18720384
83Abnormal lung lobation (HP:0002101)2.16194734
84Glossoptosis (HP:0000162)2.15678551
85CNS demyelination (HP:0007305)2.15183030
86Optic disc pallor (HP:0000543)2.15111072
87Increased intramyocellular lipid droplets (HP:0012240)2.15092395
88Postnatal microcephaly (HP:0005484)2.14799306
89Abnormality of alanine metabolism (HP:0010916)2.14286357
90Hyperalaninemia (HP:0003348)2.14286357
91Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.14286357
92Meckel diverticulum (HP:0002245)2.13874818
93Impulsivity (HP:0100710)2.13471130
94Progressive muscle weakness (HP:0003323)2.11105109
95Cerebral edema (HP:0002181)2.10984324
96Abnormality of the heme biosynthetic pathway (HP:0010472)2.09941427
97Abnormality of the preputium (HP:0100587)2.08713232
98Pancytopenia (HP:0001876)2.06471308
99Abnormality of the ileum (HP:0001549)2.06335018
100Respiratory difficulties (HP:0002880)2.03166937
101Neoplasm of the pancreas (HP:0002894)2.02561831
102X-linked dominant inheritance (HP:0001423)2.02499135
103Amniotic constriction ring (HP:0009775)2.00753181
104Abnormality of placental membranes (HP:0011409)2.00753181
105Glycosuria (HP:0003076)2.00693425
106Abnormality of urine glucose concentration (HP:0011016)2.00693425
107Muscle fiber atrophy (HP:0100295)1.98163420
108Progressive external ophthalmoplegia (HP:0000590)1.96876983
109Aplasia/hypoplasia of the uterus (HP:0008684)1.94683183
110Hypoplasia of the radius (HP:0002984)1.94092832
111Atrophy/Degeneration involving motor neurons (HP:0007373)1.92499658
112Hyperphosphaturia (HP:0003109)1.92073700
113Medulloblastoma (HP:0002885)1.90224963
11411 pairs of ribs (HP:0000878)1.87190714
115Type 2 muscle fiber atrophy (HP:0003554)1.87063425
116Type I transferrin isoform profile (HP:0003642)1.86342391
117Nausea (HP:0002018)1.86191747
118Facial cleft (HP:0002006)1.82955620
119Sparse eyelashes (HP:0000653)1.81017874
120Tracheoesophageal fistula (HP:0002575)1.79994335
121Bone marrow hypocellularity (HP:0005528)1.79148008
122Atresia of the external auditory canal (HP:0000413)1.79095862
123Severe visual impairment (HP:0001141)1.78994702
124Chromosomal breakage induced by crosslinking agents (HP:0003221)1.78678697
125Blindness (HP:0000618)1.78150756
126Asplenia (HP:0001746)1.77299080
127Abnormality of aromatic amino acid family metabolism (HP:0004338)1.77235352
128Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.74942525
129Hypertensive crisis (HP:0100735)1.74811571
130Gliosis (HP:0002171)1.72566355
131Paralysis (HP:0003470)1.71487484
132Abnormal pupillary function (HP:0007686)1.71473095
133Hypoplastic pelvis (HP:0008839)1.70283317
134Abnormality of methionine metabolism (HP:0010901)1.68898805
135Death in infancy (HP:0001522)1.65491199
136Congenital ichthyosiform erythroderma (HP:0007431)1.64858408
137Opisthotonus (HP:0002179)1.59910877
138Ragged-red muscle fibers (HP:0003200)1.56430860
139Hypoplasia of the uterus (HP:0000013)1.56054767
140Redundant skin (HP:0001582)1.55335508

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.85646909
2VRK25.24215361
3WEE13.88593194
4EIF2AK13.52060221
5STK163.51968180
6TLK13.25013077
7NME23.17261918
8TESK22.90063200
9SRPK12.69237773
10VRK12.32526054
11TSSK62.27182356
12PLK42.25873548
13CDC72.17700453
14CDK192.17061507
15NME12.12270015
16DYRK32.01246961
17PNCK1.91727657
18EIF2AK31.68197905
19MKNK11.65668677
20MKNK21.58660567
21ACVR1B1.56326682
22AURKA1.55983922
23PLK11.55515102
24BRAF1.54388821
25NEK11.50765528
26CCNB11.50335516
27MAP3K121.49702133
28BRSK21.48973466
29DYRK21.46492683
30PDK21.42350257
31PIM21.42008603
32NEK21.41182851
33CDK71.35651012
34PLK31.32623287
35LIMK11.26536066
36TTK1.25578579
37IRAK31.24063682
38TESK11.21016323
39BCKDK1.19995417
40AURKB1.19636259
41SMG11.18865812
42BRSK11.17710366
43TAOK21.14726221
44NUAK11.07645118
45ARAF1.03906088
46MARK11.03227739
47CHEK21.03140262
48TRIM281.03123744
49MAP3K111.00412218
50ATR0.96739396
51KDR0.92952851
52RPS6KB20.89561149
53PRKCI0.86248927
54TAF10.85297344
55PAK10.84504535
56MAP3K80.84335530
57ZAK0.83643839
58CDK80.82165989
59CSNK2A20.79126163
60MAP4K20.78937075
61PBK0.76869182
62MAPKAPK30.75421668
63CSNK2A10.71582982
64CHEK10.71446198
65PAK40.68732815
66MUSK0.67847026
67SCYL20.67200401
68IKBKB0.67137457
69DAPK30.66585801
70ILK0.66196464
71RPS6KA40.66083194
72ERN10.65562466
73RPS6KA50.65031434
74EPHA20.62202896
75ABL20.61524785
76MAP4K10.58740702
77TGFBR10.57522754
78PASK0.57307347
79TAOK10.55670966
80CDK20.54180621
81MAP3K100.52910539
82CSNK1G30.51728228
83EIF2AK20.51411641
84UHMK10.50808877
85STK40.50656029
86CDK11A0.48426207
87IRAK20.48222598
88CDK40.47140776
89LATS20.41381300
90MAP3K30.40681076
91AKT20.40627117
92MST1R0.40354136
93CSNK1E0.40163840
94BMPR1B0.40135869
95DAPK10.40083359
96CDK10.39997418
97INSRR0.39749939
98ATM0.39426294
99CDK140.38865456
100CDK180.37867916
101PHKG10.37287338
102PHKG20.37287338
103CDK150.35824531
104CDK90.34334831
105BRD40.31753127
106MAP2K20.31149980
107STK100.30551402
108LRRK20.30320045
109PRKG20.29655494
110RAF10.28180205
111CAMK2G0.27247664
112GRK60.27052903
113MAPK90.26340442
114TBK10.26220401
115MAP2K30.24577033
116MST40.24365761
117TNK20.24214035
118ALK0.24146994
119PIM10.22916344
120MAPKAPK50.22065026
121IRAK40.18994557
122MINK10.18710597
123MAPK130.18259792
124CSNK1G10.17317771
125MAP2K60.16642833
126BCR0.15405887
127PRKDC0.14846790
128MYLK0.13961664
129MAPK40.13731707

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.09300569
2Proteasome_Homo sapiens_hsa030504.49889740
3RNA polymerase_Homo sapiens_hsa030204.44895140
4DNA replication_Homo sapiens_hsa030304.12794167
5Mismatch repair_Homo sapiens_hsa034303.65737228
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.56184453
7Spliceosome_Homo sapiens_hsa030403.45515263
8Pyrimidine metabolism_Homo sapiens_hsa002402.96921070
9RNA transport_Homo sapiens_hsa030132.81475014
10Nucleotide excision repair_Homo sapiens_hsa034202.62007666
11Base excision repair_Homo sapiens_hsa034102.60227473
12Oxidative phosphorylation_Homo sapiens_hsa001902.58941507
13Homologous recombination_Homo sapiens_hsa034402.56160278
14Parkinsons disease_Homo sapiens_hsa050122.48342686
15Huntingtons disease_Homo sapiens_hsa050162.05902821
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.05139997
17Basal transcription factors_Homo sapiens_hsa030221.95124438
18One carbon pool by folate_Homo sapiens_hsa006701.86260922
19Cell cycle_Homo sapiens_hsa041101.83641337
20Fanconi anemia pathway_Homo sapiens_hsa034601.74679077
21RNA degradation_Homo sapiens_hsa030181.72408707
22Purine metabolism_Homo sapiens_hsa002301.70250783
23Protein export_Homo sapiens_hsa030601.60214429
24Alzheimers disease_Homo sapiens_hsa050101.49016936
25mRNA surveillance pathway_Homo sapiens_hsa030151.31799809
26Sulfur relay system_Homo sapiens_hsa041221.29726802
27Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.27110885
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.25843316
29Non-homologous end-joining_Homo sapiens_hsa034501.19826640
30Sulfur metabolism_Homo sapiens_hsa009201.08873691
31Epstein-Barr virus infection_Homo sapiens_hsa051691.06235096
32Vitamin B6 metabolism_Homo sapiens_hsa007501.04083484
33Folate biosynthesis_Homo sapiens_hsa007901.04008528
34Cardiac muscle contraction_Homo sapiens_hsa042601.01499236
35p53 signaling pathway_Homo sapiens_hsa041151.01110944
36Cysteine and methionine metabolism_Homo sapiens_hsa002700.99078970
37Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.92894807
38Systemic lupus erythematosus_Homo sapiens_hsa053220.92012408
39Oocyte meiosis_Homo sapiens_hsa041140.78431718
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.76032321
41Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.73295568
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71173354
43Pentose phosphate pathway_Homo sapiens_hsa000300.70614277
44Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.69793999
45Biosynthesis of amino acids_Homo sapiens_hsa012300.67275784
46Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63072347
47Glutathione metabolism_Homo sapiens_hsa004800.60712254
48Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.60198290
49Cyanoamino acid metabolism_Homo sapiens_hsa004600.55843092
50Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.55249960
51Metabolic pathways_Homo sapiens_hsa011000.54962409
52Alcoholism_Homo sapiens_hsa050340.54361143
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.54275406
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.48981382
55Peroxisome_Homo sapiens_hsa041460.45834639
56Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43519728
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.41913223
58Carbon metabolism_Homo sapiens_hsa012000.40614936
59Propanoate metabolism_Homo sapiens_hsa006400.39873611
60Viral carcinogenesis_Homo sapiens_hsa052030.39128448
61Regulation of autophagy_Homo sapiens_hsa041400.37693013
62Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.34372524
63Steroid biosynthesis_Homo sapiens_hsa001000.33895377
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33606844
65Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32838307
66Allograft rejection_Homo sapiens_hsa053300.30928481
67Asthma_Homo sapiens_hsa053100.29981383
68Fructose and mannose metabolism_Homo sapiens_hsa000510.29803082
69Herpes simplex infection_Homo sapiens_hsa051680.29034100
70Thyroid cancer_Homo sapiens_hsa052160.27944223
71Arginine and proline metabolism_Homo sapiens_hsa003300.27858768
722-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.26678348
73HTLV-I infection_Homo sapiens_hsa051660.26460246
74Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.26435667
75Autoimmune thyroid disease_Homo sapiens_hsa053200.25934919
76Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.25762061
77Basal cell carcinoma_Homo sapiens_hsa052170.24969160
78Arachidonic acid metabolism_Homo sapiens_hsa005900.24005495
79Antigen processing and presentation_Homo sapiens_hsa046120.23386116
80Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.22191893
81Hedgehog signaling pathway_Homo sapiens_hsa043400.21921717
82Graft-versus-host disease_Homo sapiens_hsa053320.21874930
83Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.21065920
84N-Glycan biosynthesis_Homo sapiens_hsa005100.20843402
85Intestinal immune network for IgA production_Homo sapiens_hsa046720.16155256
86Pentose and glucuronate interconversions_Homo sapiens_hsa000400.14669971
87Rheumatoid arthritis_Homo sapiens_hsa053230.14357265
88Legionellosis_Homo sapiens_hsa051340.13858800
89Linoleic acid metabolism_Homo sapiens_hsa005910.13544803
90Phototransduction_Homo sapiens_hsa047440.13529763
91Type I diabetes mellitus_Homo sapiens_hsa049400.13264787
92Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.11640769
93Phenylalanine metabolism_Homo sapiens_hsa003600.10471832
94Hippo signaling pathway_Homo sapiens_hsa043900.10228267
95Bladder cancer_Homo sapiens_hsa052190.10015285
96Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.09856744
97Vitamin digestion and absorption_Homo sapiens_hsa049770.09678844
98Pyruvate metabolism_Homo sapiens_hsa006200.09637506
99Galactose metabolism_Homo sapiens_hsa000520.09272922
100Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.08428816
101Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.06851082
102Collecting duct acid secretion_Homo sapiens_hsa049660.06836903
103Vibrio cholerae infection_Homo sapiens_hsa051100.06448654
104Fatty acid metabolism_Homo sapiens_hsa012120.06116012
105Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.05798561
106Fatty acid elongation_Homo sapiens_hsa000620.05790216
107HIF-1 signaling pathway_Homo sapiens_hsa040660.04074503
108Wnt signaling pathway_Homo sapiens_hsa043100.02923480
109Renin-angiotensin system_Homo sapiens_hsa046140.02864190
110Tyrosine metabolism_Homo sapiens_hsa003500.01778261
111Shigellosis_Homo sapiens_hsa051310.01330479
112Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072-0.0441460
113Colorectal cancer_Homo sapiens_hsa05210-0.0356789
114MicroRNAs in cancer_Homo sapiens_hsa05206-0.0353312
115Ether lipid metabolism_Homo sapiens_hsa00565-0.0317894
116Selenocompound metabolism_Homo sapiens_hsa00450-0.0239291
117Primary immunodeficiency_Homo sapiens_hsa05340-0.0204557
118Melanoma_Homo sapiens_hsa05218-0.0189666
119Apoptosis_Homo sapiens_hsa04210-0.0091991
120Pathways in cancer_Homo sapiens_hsa05200-0.0052922

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