SSU72

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.15978078
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.99011726
3ribosomal small subunit assembly (GO:0000028)4.96277365
4DNA deamination (GO:0045006)4.82005771
5ATP synthesis coupled proton transport (GO:0015986)4.75889505
6energy coupled proton transport, down electrochemical gradient (GO:0015985)4.75889505
7transcription elongation from RNA polymerase III promoter (GO:0006385)4.67662329
8termination of RNA polymerase III transcription (GO:0006386)4.67662329
9negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.61843345
10ribosomal small subunit biogenesis (GO:0042274)4.43213179
11cullin deneddylation (GO:0010388)4.35687055
12positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.29710433
13regulation of cellular amino acid metabolic process (GO:0006521)4.28696731
14maturation of SSU-rRNA (GO:0030490)4.28660130
15protein deneddylation (GO:0000338)4.25335669
16antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:4.23209404
17protein neddylation (GO:0045116)4.21025225
18regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.17767513
19DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.17589903
20negative regulation of ligase activity (GO:0051352)4.16893733
21negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.16893733
22viral transcription (GO:0019083)4.15507309
23signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)4.08994057
24intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)4.08994057
25translational termination (GO:0006415)4.08817659
26anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.07455053
27signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)4.06005037
28signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)4.06005037
29signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)4.06005037
30antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)4.05698049
31chaperone-mediated protein transport (GO:0072321)4.05252537
32protein maturation by protein folding (GO:0022417)4.04722356
337-methylguanosine mRNA capping (GO:0006370)3.93788953
34L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.93654197
35SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.93261862
36cotranslational protein targeting to membrane (GO:0006613)3.91529661
37signal transduction involved in DNA damage checkpoint (GO:0072422)3.91091632
38signal transduction involved in DNA integrity checkpoint (GO:0072401)3.91091632
39RNA capping (GO:0036260)3.87460681
407-methylguanosine RNA capping (GO:0009452)3.87460681
41mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.86765464
42signal transduction involved in cell cycle checkpoint (GO:0072395)3.84988936
43protein targeting to ER (GO:0045047)3.84210296
44protein complex biogenesis (GO:0070271)3.83108422
45mitochondrial respiratory chain complex I assembly (GO:0032981)3.81777978
46NADH dehydrogenase complex assembly (GO:0010257)3.81777978
47mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.81777978
48formation of translation preinitiation complex (GO:0001731)3.76719677
49positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.75461754
50establishment of protein localization to mitochondrial membrane (GO:0090151)3.72575911
51oxidative phosphorylation (GO:0006119)3.72448329
52deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.70258745
53protein localization to endoplasmic reticulum (GO:0070972)3.69600075
54translation (GO:0006412)3.69578136
55ribosomal large subunit biogenesis (GO:0042273)3.69163530
56translational elongation (GO:0006414)3.62696120
57establishment of protein localization to endoplasmic reticulum (GO:0072599)3.62101125
58positive regulation of ligase activity (GO:0051351)3.61257690
59mitochondrial respiratory chain complex assembly (GO:0033108)3.58559650
60respiratory electron transport chain (GO:0022904)3.53536375
61translational initiation (GO:0006413)3.48552194
62electron transport chain (GO:0022900)3.45819634
63protein targeting to mitochondrion (GO:0006626)3.41030919
64viral life cycle (GO:0019058)3.37109014
65regulation of mitochondrial translation (GO:0070129)3.36539894
66establishment of protein localization to mitochondrion (GO:0072655)3.35934298
67ribonucleoprotein complex biogenesis (GO:0022613)3.35525508
68respiratory chain complex IV assembly (GO:0008535)3.32686359
69cellular protein complex disassembly (GO:0043624)3.31480231
70antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)3.30486703
71guanosine-containing compound biosynthetic process (GO:1901070)3.30370920
72pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.29350425
73viral mRNA export from host cell nucleus (GO:0046784)3.26424488
74rRNA modification (GO:0000154)3.25286841
75cellular component biogenesis (GO:0044085)3.24334971
76regulation of ubiquitin-protein transferase activity (GO:0051438)3.23597469
77regulation of cellular amine metabolic process (GO:0033238)3.23197453
78GDP-mannose metabolic process (GO:0019673)3.23164476
79DNA strand elongation (GO:0022616)3.22415338
80DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.22142705
81inner mitochondrial membrane organization (GO:0007007)3.21833790
82GTP biosynthetic process (GO:0006183)3.21257888
83positive regulation of cell cycle arrest (GO:0071158)3.19753765
84transcription from mitochondrial promoter (GO:0006390)3.19652786
852-deoxyribonucleotide biosynthetic process (GO:0009265)3.17867519
86deoxyribose phosphate biosynthetic process (GO:0046385)3.17867519
87spliceosomal snRNP assembly (GO:0000387)3.17750577
88pseudouridine synthesis (GO:0001522)3.16103423
89base-excision repair, AP site formation (GO:0006285)3.15521792
90regulation of ligase activity (GO:0051340)3.13983843
91L-methionine salvage (GO:0071267)3.13495196
92L-methionine biosynthetic process (GO:0071265)3.13495196
93amino acid salvage (GO:0043102)3.13495196
94autophagic vacuole fusion (GO:0000046)3.13490058
95cytochrome complex assembly (GO:0017004)3.13412442
96pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.13190261
97protein localization to mitochondrion (GO:0070585)3.13007741
98peptidyl-histidine modification (GO:0018202)3.11317026
99nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.10516601
100transcription-coupled nucleotide-excision repair (GO:0006283)3.10105423
101pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.09930304
102nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.05879148
103pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.05500591
104telomere maintenance via semi-conservative replication (GO:0032201)3.05051517
105rRNA processing (GO:0006364)3.03721462
106DNA strand elongation involved in DNA replication (GO:0006271)3.02449476
107exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.02061466
108RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.00611284
109tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.00611284
110transcription elongation from RNA polymerase I promoter (GO:0006362)3.00199919
111CTP biosynthetic process (GO:0006241)2.97816912
112CTP metabolic process (GO:0046036)2.97816912
113rRNA methylation (GO:0031167)2.97694152
114maturation of 5.8S rRNA (GO:0000460)2.97613507
115DNA replication checkpoint (GO:0000076)2.97334212
116UTP biosynthetic process (GO:0006228)2.96322813
117transcription elongation from RNA polymerase II promoter (GO:0006368)2.94948015
118intracellular protein transmembrane import (GO:0044743)2.93983955
119rRNA metabolic process (GO:0016072)2.91466775
120deoxyribonucleotide catabolic process (GO:0009264)2.89694194
121establishment of integrated proviral latency (GO:0075713)2.89019212
122mitochondrial transport (GO:0006839)2.88107766
123purine nucleoside triphosphate biosynthetic process (GO:0009145)2.87821790
124intracellular protein transmembrane transport (GO:0065002)2.87572855
125purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.87518635
126telomere maintenance via recombination (GO:0000722)2.85542806
127pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.85060926
128ribosome biogenesis (GO:0042254)2.83335772
129telomere maintenance via telomere lengthening (GO:0010833)2.82021381
130mannosylation (GO:0097502)2.81812913
131ribonucleoside triphosphate biosynthetic process (GO:0009201)2.80768590
132protein K6-linked ubiquitination (GO:0085020)2.80139609
133ATP biosynthetic process (GO:0006754)2.78735378

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.88958002
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.77111620
3* JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.28521049
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.27136042
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.87588014
6* ETS1_20019798_ChIP-Seq_JURKAT_Human3.76747903
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.56294304
8CREB1_15753290_ChIP-ChIP_HEK293T_Human3.56284066
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.52393004
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.40270699
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.11409756
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.09087087
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.08287565
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.07929533
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.98979797
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.96264979
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.93343114
18E2F7_22180533_ChIP-Seq_HELA_Human2.87983673
19* VDR_23849224_ChIP-Seq_CD4+_Human2.80271332
20* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.62616249
21* DCP1A_22483619_ChIP-Seq_HELA_Human2.51466676
22SRF_21415370_ChIP-Seq_HL-1_Mouse2.49024253
23MYC_19079543_ChIP-ChIP_MESCs_Mouse2.44115999
24E2F1_18555785_ChIP-Seq_MESCs_Mouse2.41160115
25* XRN2_22483619_ChIP-Seq_HELA_Human2.30505994
26ELK1_19687146_ChIP-ChIP_HELA_Human2.28620522
27* THAP11_20581084_ChIP-Seq_MESCs_Mouse2.27882869
28FOXP3_21729870_ChIP-Seq_TREG_Human2.26480864
29PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.26278835
30NELFA_20434984_ChIP-Seq_ESCs_Mouse2.19192748
31FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.17187107
32GABP_19822575_ChIP-Seq_HepG2_Human2.13922050
33* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.08620954
34YY1_21170310_ChIP-Seq_MESCs_Mouse2.07334856
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.97320594
36HOXB4_20404135_ChIP-ChIP_EML_Mouse1.93548513
37FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.90718056
38* TTF2_22483619_ChIP-Seq_HELA_Human1.87560686
39FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.80214537
40ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.73651314
41CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.68902482
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.66937804
43ELK1_22589737_ChIP-Seq_MCF10A_Human1.66359253
44IRF8_21731497_ChIP-ChIP_J774_Mouse1.60376069
45IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.57282820
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.55493508
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.51386072
48ERG_20887958_ChIP-Seq_HPC-7_Mouse1.49032570
49* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.48833831
50MYCN_18555785_ChIP-Seq_MESCs_Mouse1.48650699
51NANOG_18555785_ChIP-Seq_MESCs_Mouse1.47473557
52SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.46466625
53MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.42332420
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.40431734
55DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.40369925
56* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37334807
57TET1_21451524_ChIP-Seq_MESCs_Mouse1.36042679
58TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.35076338
59CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.35023696
60PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.32317207
61ELF1_20517297_ChIP-Seq_JURKAT_Human1.32245191
62FOXP1_21924763_ChIP-Seq_HESCs_Human1.31350476
63MYC_22102868_ChIP-Seq_BL_Human1.31300275
64ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.30372887
65TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30019833
66VDR_21846776_ChIP-Seq_THP-1_Human1.27480811
67YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27477943
68POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.24800523
69SPI1_23547873_ChIP-Seq_NB4_Human1.24746344
70* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.23336257
71* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.23239022
72MYC_18940864_ChIP-ChIP_HL60_Human1.22768028
73* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.18054985
74BCL6_27268052_Chip-Seq_Bcells_Human1.16852861
75* P68_20966046_ChIP-Seq_HELA_Human1.16769159
76RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.16526802
77CTCF_26484167_Chip-Seq_Bcells_Mouse1.16457064
78YY1_22570637_ChIP-Seq_MALME-3M_Human1.14075124
79PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13402147
80BCOR_27268052_Chip-Seq_Bcells_Human1.06916073
81CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.05616348
82IRF8_22096565_ChIP-ChIP_GC-B_Human1.04484974
83SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.04401130
84CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03926456
85BP1_19119308_ChIP-ChIP_Hs578T_Human1.02394043
86* KDM5A_27292631_Chip-Seq_BREAST_Human1.01377255
87E2F1_20622854_ChIP-Seq_HELA_Human1.00615951
88* PHF8_20622854_ChIP-Seq_HELA_Human1.00491128
89SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00481818
90RARB_24833708_ChIP-Seq_LIVER_Mouse1.00303294
91* SA1_27219007_Chip-Seq_ERYTHROID_Human1.00185985
92KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.00127521
93* SA1_27219007_Chip-Seq_Bcells_Human0.98822370
94TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97170473
95FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95948316
96TFEB_21752829_ChIP-Seq_HELA_Human0.95602743
97PU.1_20513432_ChIP-Seq_Bcells_Mouse0.94322863
98ZNF263_19887448_ChIP-Seq_K562_Human0.93719530
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.93384997
100IRF1_19129219_ChIP-ChIP_H3396_Human0.93002717
101HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.92314168
102* MAF_26560356_Chip-Seq_TH2_Human0.92099596
103RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.91936895
104* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.91906310
105* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.91723169
106CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.90575888
107CIITA_25753668_ChIP-Seq_RAJI_Human0.88561141
108POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.86773566
109* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.85741471
110GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.85368244
111STAT4_19710469_ChIP-ChIP_TH1__Mouse0.85361815
112CTCF_18555785_ChIP-Seq_MESCs_Mouse0.84736087
113E2F1_21310950_ChIP-Seq_MCF-7_Human0.84003734
114KAP1_22055183_ChIP-Seq_ESCs_Mouse0.83949479
115STAT3_1855785_ChIP-Seq_MESCs_Mouse0.79184690
116EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.78611238
117KLF4_18555785_ChIP-Seq_MESCs_Mouse0.78197735
118OCT4_18692474_ChIP-Seq_MEFs_Mouse0.76938836
119SOX17_20123909_ChIP-Seq_XEN_Mouse0.75602313
120CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.75331044
121SOX2_18692474_ChIP-Seq_MEFs_Mouse0.75084487
122RBPJ_22232070_ChIP-Seq_NCS_Mouse0.72885921
123TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.72065539
124ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.70984593
125SRY_22984422_ChIP-ChIP_TESTIS_Rat0.67355687
126MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.66567985
127* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.65359771

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.37990066
2MP0004957_abnormal_blastocyst_morpholog3.10197885
3MP0003186_abnormal_redox_activity2.70909952
4MP0001835_abnormal_antigen_presentation2.56655752
5MP0009785_altered_susceptibility_to2.51820735
6MP0004147_increased_porphyrin_level2.50636136
7MP0002148_abnormal_hypersensitivity_rea2.44935559
8MP0003718_maternal_effect2.42612001
9MP0005671_abnormal_response_to2.41739514
10MP0008058_abnormal_DNA_repair2.41489308
11MP0008057_abnormal_DNA_replication2.35797564
12MP0003077_abnormal_cell_cycle2.34527265
13MP0009379_abnormal_foot_pigmentation2.31897236
14MP0010094_abnormal_chromosome_stability2.29465950
15MP0002163_abnormal_gland_morphology2.28394913
16MP0008260_abnormal_autophagy2.16617982
17MP0008932_abnormal_embryonic_tissue2.13345040
18MP0001529_abnormal_vocalization2.13344795
19MP0009333_abnormal_splenocyte_physiolog2.10429022
20MP0001986_abnormal_taste_sensitivity2.08280857
21MP0003172_abnormal_lysosome_physiology2.04547244
22MP0003111_abnormal_nucleus_morphology1.97459629
23MP0003878_abnormal_ear_physiology1.96708084
24MP0005377_hearing/vestibular/ear_phenot1.96708084
25MP0001873_stomach_inflammation1.91399996
26MP0003786_premature_aging1.89900365
27MP0006035_abnormal_mitochondrial_morpho1.86144711
28MP0002132_abnormal_respiratory_system1.86076816
29MP0006036_abnormal_mitochondrial_physio1.84101034
30MP0001905_abnormal_dopamine_level1.79230157
31MP0000372_irregular_coat_pigmentation1.79179766
32MP0003880_abnormal_central_pattern1.75212227
33MP0003806_abnormal_nucleotide_metabolis1.72510046
34MP0002837_dystrophic_cardiac_calcinosis1.71031438
35MP0002638_abnormal_pupillary_reflex1.68598435
36MP0005000_abnormal_immune_tolerance1.65253399
37MP0003436_decreased_susceptibility_to1.62305650
38MP0005025_abnormal_response_to1.62214116
39MP0008995_early_reproductive_senescence1.57754457
40MP0009840_abnormal_foam_cell1.56989479
41MP0008872_abnormal_physiological_respon1.50485121
42MP0003123_paternal_imprinting1.50280429
43MP0001853_heart_inflammation1.49334634
44MP0002277_abnormal_respiratory_mucosa1.45398420
45MP0001542_abnormal_bone_strength1.44388195
46MP0002723_abnormal_immune_serum1.43026067
47MP0000490_abnormal_crypts_of1.41829308
48MP0005636_abnormal_mineral_homeostasis1.38572335
49MP0005451_abnormal_body_composition1.37955729
50MP0002396_abnormal_hematopoietic_system1.37523558
51MP0002420_abnormal_adaptive_immunity1.35688877
52MP0009278_abnormal_bone_marrow1.35587673
53MP0001819_abnormal_immune_cell1.35524285
54MP0002452_abnormal_antigen_presenting1.34362644
55MP0003763_abnormal_thymus_physiology1.34136201
56MP0008877_abnormal_DNA_methylation1.31863346
57MP0002419_abnormal_innate_immunity1.30757625
58MP0001984_abnormal_olfaction1.30647532
59MP0005084_abnormal_gallbladder_morpholo1.30222520
60MP0001727_abnormal_embryo_implantation1.28952335
61MP0001800_abnormal_humoral_immune1.28559139
62MP0000685_abnormal_immune_system1.28448503
63MP0002102_abnormal_ear_morphology1.27440810
64MP0006082_CNS_inflammation1.27316582
65MP0005075_abnormal_melanosome_morpholog1.26395555
66MP0005646_abnormal_pituitary_gland1.25982865
67MP0001764_abnormal_homeostasis1.25049455
68MP0002693_abnormal_pancreas_physiology1.21467454
69MP0003724_increased_susceptibility_to1.21445037
70MP0002405_respiratory_system_inflammati1.21392030
71MP0002938_white_spotting1.19899721
72MP0006292_abnormal_olfactory_placode1.19228270
73MP0002736_abnormal_nociception_after1.19084685
74MP0000358_abnormal_cell_content/1.18741005
75MP0005171_absent_coat_pigmentation1.18678032
76MP0008007_abnormal_cellular_replicative1.17085437
77MP0005408_hypopigmentation1.16609269
78MP0006276_abnormal_autonomic_nervous1.15364329
79MP0004145_abnormal_muscle_electrophysio1.12548476
80MP0002398_abnormal_bone_marrow1.12143123
81MP0001790_abnormal_immune_system1.10069680
82MP0005387_immune_system_phenotype1.10069680
83MP0009697_abnormal_copulation1.08830628
84MP0003136_yellow_coat_color1.08791657
85MP0008789_abnormal_olfactory_epithelium1.08383335
86MP0000716_abnormal_immune_system1.08041010
87MP0005058_abnormal_lysosome_morphology1.07998759
88MP0000689_abnormal_spleen_morphology1.05872101
89MP0001944_abnormal_pancreas_morphology1.05491816
90MP0010386_abnormal_urinary_bladder1.03701112
91MP0002095_abnormal_skin_pigmentation1.02950619
92MP0000343_altered_response_to1.02244140
93MP0001545_abnormal_hematopoietic_system1.01955062
94MP0005397_hematopoietic_system_phenotyp1.01955062
95MP0005379_endocrine/exocrine_gland_phen1.01407255
96MP0002722_abnormal_immune_system1.00686215
97MP0002429_abnormal_blood_cell1.00588673
98MP0000313_abnormal_cell_death0.99993943
99MP0002138_abnormal_hepatobiliary_system0.99817040
100MP0005332_abnormal_amino_acid0.99307005
101MP0001188_hyperpigmentation0.95925348
102MP0003315_abnormal_perineum_morphology0.95325727
103MP0002735_abnormal_chemical_nociception0.92724135
104MP0001845_abnormal_inflammatory_respons0.92251827
105MP0003075_altered_response_to0.91472335
106MP0005310_abnormal_salivary_gland0.90412564
107MP0000703_abnormal_thymus_morphology0.88847477
108MP0000015_abnormal_ear_pigmentation0.88378026
109MP0001730_embryonic_growth_arrest0.87666689
110MP0008469_abnormal_protein_level0.86719452
111MP0004381_abnormal_hair_follicle0.86520018
112MP0005174_abnormal_tail_pigmentation0.85701166
113MP0002876_abnormal_thyroid_physiology0.85508467
114MP0000858_altered_metastatic_potential0.83495578
115MP0002822_catalepsy0.83400712
116MP0003866_abnormal_defecation0.83120937
117MP0002234_abnormal_pharynx_morphology0.83071275
118MP0003011_delayed_dark_adaptation0.82934374
119MP0002019_abnormal_tumor_incidence0.82402950
120MP0002909_abnormal_adrenal_gland0.82260388
121MP0004782_abnormal_surfactant_physiolog0.82219538
122MP0005464_abnormal_platelet_physiology0.80409879
123MP0000371_diluted_coat_color0.79824758
124MP0002653_abnormal_ependyma_morphology0.79595423
125MP0000350_abnormal_cell_proliferation0.79410176
126MP0003646_muscle_fatigue0.79169145
127MP0004142_abnormal_muscle_tone0.78796977
128MP0001663_abnormal_digestive_system0.78659961
129MP0002160_abnormal_reproductive_system0.77752354
130MP0005220_abnormal_exocrine_pancreas0.77357497
131MP0009672_abnormal_birth_weight0.76200217
132MP0004043_abnormal_pH_regulation0.74852410
133MP0001919_abnormal_reproductive_system0.74476129
134MP0002751_abnormal_autonomic_nervous0.73897279
135MP0005330_cardiomyopathy0.73710156
136MP0001661_extended_life_span0.73631295
137MP0010030_abnormal_orbit_morphology0.73153900
138MP0000613_abnormal_salivary_gland0.73062192
139MP0005389_reproductive_system_phenotype0.72621576
140MP0008873_increased_physiological_sensi0.72474402
141MP0002210_abnormal_sex_determination0.71057076
142MP0001485_abnormal_pinna_reflex0.70127643
143MP0000681_abnormal_thyroid_gland0.69754024
144MP0004808_abnormal_hematopoietic_stem0.69595405
145MP0005253_abnormal_eye_physiology0.69056650
146MP0003137_abnormal_impulse_conducting0.66594375
147MP0001968_abnormal_touch/_nociception0.65150201
148MP0006072_abnormal_retinal_apoptosis0.64371554

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.39296242
2Abnormal mitochondria in muscle tissue (HP:0008316)4.83762774
3Mitochondrial inheritance (HP:0001427)4.82229809
4Hepatocellular necrosis (HP:0001404)4.24059399
5Acute encephalopathy (HP:0006846)4.23514731
6Progressive macrocephaly (HP:0004481)4.21310396
7Increased CSF lactate (HP:0002490)4.15674862
8Abnormality of cells of the erythroid lineage (HP:0012130)4.01761127
9Increased hepatocellular lipid droplets (HP:0006565)3.88938791
10Birth length less than 3rd percentile (HP:0003561)3.65428928
11Increased serum pyruvate (HP:0003542)3.60598272
12Abnormality of glycolysis (HP:0004366)3.60598272
13Abnormal number of erythroid precursors (HP:0012131)3.57638042
14Decreased activity of mitochondrial respiratory chain (HP:0008972)3.57342064
15Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.57342064
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.55243075
17Hepatic necrosis (HP:0002605)3.51959652
183-Methylglutaconic aciduria (HP:0003535)3.51780976
19Renal Fanconi syndrome (HP:0001994)3.47998008
20Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.45074126
21Methylmalonic aciduria (HP:0012120)3.43879449
22Lipid accumulation in hepatocytes (HP:0006561)3.30633839
23Exertional dyspnea (HP:0002875)3.21229615
24Increased serum lactate (HP:0002151)3.18057296
25Cerebral hypomyelination (HP:0006808)3.11868504
26Reticulocytopenia (HP:0001896)3.11576615
27Exercise intolerance (HP:0003546)2.97185789
28Testicular atrophy (HP:0000029)2.95524360
29Lactic acidosis (HP:0003128)2.91505841
30Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.87923201
31Type I transferrin isoform profile (HP:0003642)2.86431844
32Respiratory failure (HP:0002878)2.85047897
33Microvesicular hepatic steatosis (HP:0001414)2.83953129
34Hypoplasia of the fovea (HP:0007750)2.83254439
35Aplasia/Hypoplasia of the fovea (HP:0008060)2.83254439
36Breast hypoplasia (HP:0003187)2.82667265
37Petechiae (HP:0000967)2.80462001
38Aplastic anemia (HP:0001915)2.79241779
39Opisthotonus (HP:0002179)2.76927113
40Methylmalonic acidemia (HP:0002912)2.76846002
41Increased intramyocellular lipid droplets (HP:0012240)2.71424068
42Macrocytic anemia (HP:0001972)2.70847211
43Optic disc pallor (HP:0000543)2.70400485
44Respiratory difficulties (HP:0002880)2.67110940
45Spastic paraparesis (HP:0002313)2.67073355
46Cerebral edema (HP:0002181)2.66282050
47Abnormality of dicarboxylic acid metabolism (HP:0010995)2.63406991
48Dicarboxylic aciduria (HP:0003215)2.63406991
49Leukodystrophy (HP:0002415)2.61916698
50Pallor (HP:0000980)2.57352032
51Oral leukoplakia (HP:0002745)2.54949498
52Hypokinesia (HP:0002375)2.54420820
53Hyperinsulinemic hypoglycemia (HP:0000825)2.50802548
54Abnormality of alanine metabolism (HP:0010916)2.47392919
55Hyperalaninemia (HP:0003348)2.47392919
56Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.47392919
57Rough bone trabeculation (HP:0100670)2.43866429
58Poor head control (HP:0002421)2.42988451
59Aplasia/Hypoplasia of the sacrum (HP:0008517)2.42659530
60Abnormality of the labia minora (HP:0012880)2.41637592
61Abnormality of the anterior horn cell (HP:0006802)2.41623657
62Degeneration of anterior horn cells (HP:0002398)2.41623657
63Carpal bone hypoplasia (HP:0001498)2.29231123
64Abnormality of renal resorption (HP:0011038)2.28869601
65Abnormality of the fovea (HP:0000493)2.22362462
66Cleft eyelid (HP:0000625)2.21929064
67Lethargy (HP:0001254)2.20774943
68Tongue fasciculations (HP:0001308)2.17274782
69Absent rod-and cone-mediated responses on ERG (HP:0007688)2.16895644
70Ketoacidosis (HP:0001993)2.16108396
71Recurrent abscess formation (HP:0002722)2.15012968
72Progressive muscle weakness (HP:0003323)2.14793187
73Medial flaring of the eyebrow (HP:0010747)2.14675807
74Ragged-red muscle fibers (HP:0003200)2.13497969
75Reduced antithrombin III activity (HP:0001976)2.12044867
76Increased muscle lipid content (HP:0009058)2.10821333
77Aplasia/Hypoplasia of the macula (HP:0008059)2.10105864
78Pancreatic cysts (HP:0001737)2.09475907
79Irregular epiphyses (HP:0010582)2.09473021
80Abnormal hair whorl (HP:0010721)2.08737069
81Hyperthyroidism (HP:0000836)2.08269999
82Pancreatic fibrosis (HP:0100732)2.07913300
83Progressive microcephaly (HP:0000253)2.07861141
84Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.07803056
85Abnormal protein N-linked glycosylation (HP:0012347)2.07803056
86Abnormal protein glycosylation (HP:0012346)2.07803056
87Abnormal glycosylation (HP:0012345)2.07803056
88Congenital ichthyosiform erythroderma (HP:0007431)2.04436150
89Death in infancy (HP:0001522)2.00992790
90Amniotic constriction ring (HP:0009775)2.00341041
91Abnormality of placental membranes (HP:0011409)2.00341041
92Emotional lability (HP:0000712)1.99627081
93Microretrognathia (HP:0000308)1.97320906
94True hermaphroditism (HP:0010459)1.96369317
95CNS hypomyelination (HP:0003429)1.95112116
96Abnormal pupillary function (HP:0007686)1.94897241
97CNS demyelination (HP:0007305)1.94766338
98Cerebral palsy (HP:0100021)1.94323741
99Increased IgM level (HP:0003496)1.94072512
100Ketosis (HP:0001946)1.93018873
101Increased serum ferritin (HP:0003281)1.93007548
102Prolonged neonatal jaundice (HP:0006579)1.92252268
103Abnormal trabecular bone morphology (HP:0100671)1.90713928
104Aplasia/Hypoplasia affecting the retina (HP:0008061)1.90626143
105Pancytopenia (HP:0001876)1.90419627
106Type 2 muscle fiber atrophy (HP:0003554)1.90195173
107Truncus arteriosus (HP:0001660)1.89375630
108Nephrogenic diabetes insipidus (HP:0009806)1.89126716
109Poor suck (HP:0002033)1.88900693
110Abnormality of macrophages (HP:0004311)1.88075536
111Congenital primary aphakia (HP:0007707)1.87751287
112Myopathic facies (HP:0002058)1.87500496
113Postnatal microcephaly (HP:0005484)1.87203226
114Muscle fibrillation (HP:0010546)1.86026437
115Prostate neoplasm (HP:0100787)1.85726721
116Stenosis of the external auditory canal (HP:0000402)1.83314558
117Elevated erythrocyte sedimentation rate (HP:0003565)1.82723543
118Recurrent bacterial skin infections (HP:0005406)1.81588950
119Muscle fiber atrophy (HP:0100295)1.80700221
120Delusions (HP:0000746)1.79822948
121Congenital stationary night blindness (HP:0007642)1.78026518
122Hypothermia (HP:0002045)1.77292210
123Hypoplasia of the pons (HP:0012110)1.76808141
124Multiple enchondromatosis (HP:0005701)1.76722803
125Redundant skin (HP:0001582)1.75731325
126IgM deficiency (HP:0002850)1.75676520
127Paraparesis (HP:0002385)1.74751383
128Cellular immunodeficiency (HP:0005374)1.74100443
129Gait imbalance (HP:0002141)1.73819383
130Dysphonia (HP:0001618)1.72799437
131Trismus (HP:0000211)1.72278047
132Abnormality of iron homeostasis (HP:0011031)1.72159029
133Aplasia/hypoplasia of the uterus (HP:0008684)1.72096161
134Severe visual impairment (HP:0001141)1.71975770
13511 pairs of ribs (HP:0000878)1.69780252
136Stomatitis (HP:0010280)1.69758171
137Patellar aplasia (HP:0006443)1.69313744
138Sensory axonal neuropathy (HP:0003390)1.68753122
139Metaphyseal dysplasia (HP:0100255)1.67741339
140Abnormality of magnesium homeostasis (HP:0004921)1.67722486
141Premature graying of hair (HP:0002216)1.67289925
142Increased neuronal autofluorescent lipopigment (HP:0002074)1.67052962
143Abnormality of aromatic amino acid family metabolism (HP:0004338)1.66495545
144Hypoplasia of the capital femoral epiphysis (HP:0003090)1.65636988
145Secondary amenorrhea (HP:0000869)1.65489924

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.42886667
2BUB14.26221567
3NME23.31714329
4MAP3K123.28297367
5ARAF3.27682647
6STK163.13594315
7EIF2AK13.06651767
8WEE12.77654064
9EIF2AK32.70813001
10PIM22.60138621
11PBK2.36245887
12MST42.36100265
13PLK42.28182116
14TESK22.13543566
15NME11.96773408
16VRK11.95047663
17BRAF1.93015823
18ACVR1B1.86954499
19BRSK21.72739783
20SMG11.62125202
21SRPK11.58765860
22TLK11.48009967
23TSSK61.45073153
24IRAK41.42192937
25BCR1.38881141
26TNK21.37430561
27LIMK11.30948118
28CDC71.29523937
29NUAK11.21153879
30PRKD31.19842356
31MAP3K111.18817377
32STK41.17278629
33KDR1.15503322
34TXK1.12523159
35MYLK1.12514478
36PHKG21.11886208
37PHKG11.11886208
38BMPR1B1.11524527
39STK101.09721937
40SIK31.09536744
41BMPR21.08860389
42TESK11.05995690
43ABL21.04465125
44CDK191.03711238
45DYRK20.99460590
46MAP4K20.96470968
47PLK10.95981248
48AURKA0.95394878
49DYRK30.90889323
50MAP2K70.89576534
51MAPKAPK30.88799538
52CASK0.87026753
53ADRBK20.86650385
54EPHA20.84337645
55PLK30.84090722
56BRSK10.83793795
57ERN10.83411995
58RAF10.82039243
59LRRK20.80496862
60ZAK0.79918626
61PDK20.79163994
62EIF2AK20.79093379
63IRAK30.78992518
64CDK80.77233938
65IKBKB0.76236902
66RPS6KA40.76226175
67DAPK20.76042710
68RIPK40.75396471
69DAPK10.75371581
70TAOK20.73419171
71CSNK1G30.73398379
72MAPKAPK50.73075341
73TYK20.72848306
74CCNB10.71683026
75MAP3K140.70525399
76MAP2K30.70248450
77PLK20.69270215
78TBK10.69197321
79ALK0.69132568
80AKT30.68807916
81FES0.68704864
82BLK0.68389783
83MAP3K30.67967628
84RPS6KB20.67879719
85AURKB0.63660749
86CSNK2A10.62811043
87AKT20.61688848
88CSNK1G10.61152261
89MKNK10.61039977
90PAK10.60387392
91STK240.59958524
92RPS6KA50.59131548
93PASK0.58152583
94TAOK10.57450280
95TEC0.56271727
96GRK10.56214946
97MAP4K10.55187365
98MAP3K80.54978194
99SCYL20.54635177
100IKBKE0.54301749
101MAP2K20.53434189
102CDK90.53238180
103PAK60.52637366
104PIM10.52065296
105GRK70.50885616
106CAMKK20.50080549
107SYK0.49619453
108MARK30.49349072
109ZAP700.48841673
110PAK40.48000782
111CSNK1G20.47990503
112GRK50.47509751
113BCKDK0.45785080
114ILK0.45043969
115YES10.44977923
116MUSK0.44446783
117CSNK2A20.44430992
118LYN0.44292577
119CDK70.44170229
120OXSR10.43695352
121MKNK20.40635738
122LMTK20.40050361
123CHEK20.39538108
124TTK0.38924477
125PRKCD0.38021500
126HIPK20.37647889
127JAK30.36528627
128GRK60.35291411
129PRKCI0.34665859
130ADRBK10.33736055
131CLK10.33727510
132DAPK30.31821807
133MOS0.31633367
134MAP2K60.31201554
135ATR0.31157650
136KIT0.30859875
137PTK20.30048446

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.30456381
2Ribosome_Homo sapiens_hsa030104.44652740
3RNA polymerase_Homo sapiens_hsa030204.02781040
4Oxidative phosphorylation_Homo sapiens_hsa001903.72087328
5Parkinsons disease_Homo sapiens_hsa050123.18400063
6DNA replication_Homo sapiens_hsa030302.89583613
7Protein export_Homo sapiens_hsa030602.72342003
8Mismatch repair_Homo sapiens_hsa034302.55583579
9Pyrimidine metabolism_Homo sapiens_hsa002402.53178749
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.51982273
11Huntingtons disease_Homo sapiens_hsa050162.45826857
12Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.24668611
13Alzheimers disease_Homo sapiens_hsa050102.17368149
14Homologous recombination_Homo sapiens_hsa034402.13516022
15Spliceosome_Homo sapiens_hsa030402.06636191
16Nucleotide excision repair_Homo sapiens_hsa034202.03113625
17Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.88707159
18Base excision repair_Homo sapiens_hsa034101.83341875
19Basal transcription factors_Homo sapiens_hsa030221.81193039
20RNA transport_Homo sapiens_hsa030131.69292092
21Purine metabolism_Homo sapiens_hsa002301.47670803
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.39828951
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.36761794
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.36321698
25Collecting duct acid secretion_Homo sapiens_hsa049661.28003981
26Regulation of autophagy_Homo sapiens_hsa041401.25028234
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.24740801
28RNA degradation_Homo sapiens_hsa030181.22219859
29Cell cycle_Homo sapiens_hsa041101.18507222
30Cyanoamino acid metabolism_Homo sapiens_hsa004601.18437009
31SNARE interactions in vesicular transport_Homo sapiens_hsa041301.17094272
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.14598910
33Phototransduction_Homo sapiens_hsa047441.13613250
34Epstein-Barr virus infection_Homo sapiens_hsa051691.13502781
35Maturity onset diabetes of the young_Homo sapiens_hsa049501.10557449
36Sulfur metabolism_Homo sapiens_hsa009201.10176237
37Rheumatoid arthritis_Homo sapiens_hsa053231.07734126
38Folate biosynthesis_Homo sapiens_hsa007901.06040761
39Fanconi anemia pathway_Homo sapiens_hsa034601.05474118
40Vibrio cholerae infection_Homo sapiens_hsa051101.05417757
41Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.03977351
42Allograft rejection_Homo sapiens_hsa053301.02982968
43Pyruvate metabolism_Homo sapiens_hsa006201.01818093
44Carbon metabolism_Homo sapiens_hsa012001.01329220
45Selenocompound metabolism_Homo sapiens_hsa004500.99812897
46Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.98849345
47Graft-versus-host disease_Homo sapiens_hsa053320.95918829
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.93030541
49Propanoate metabolism_Homo sapiens_hsa006400.86876844
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.83441441
51Biosynthesis of amino acids_Homo sapiens_hsa012300.80604864
52Legionellosis_Homo sapiens_hsa051340.79658887
53Cardiac muscle contraction_Homo sapiens_hsa042600.78477404
54Non-homologous end-joining_Homo sapiens_hsa034500.74942472
55Peroxisome_Homo sapiens_hsa041460.72433390
56Glutathione metabolism_Homo sapiens_hsa004800.72127228
57Autoimmune thyroid disease_Homo sapiens_hsa053200.71698824
58Phagosome_Homo sapiens_hsa041450.68866183
59Tyrosine metabolism_Homo sapiens_hsa003500.67597590
60Asthma_Homo sapiens_hsa053100.67445187
61Pentose phosphate pathway_Homo sapiens_hsa000300.67042862
62Intestinal immune network for IgA production_Homo sapiens_hsa046720.66008993
63p53 signaling pathway_Homo sapiens_hsa041150.65164616
64Arachidonic acid metabolism_Homo sapiens_hsa005900.64955430
65Metabolic pathways_Homo sapiens_hsa011000.59533331
66Type I diabetes mellitus_Homo sapiens_hsa049400.59212788
67RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.58800182
68Herpes simplex infection_Homo sapiens_hsa051680.57715601
69Primary immunodeficiency_Homo sapiens_hsa053400.57620230
70One carbon pool by folate_Homo sapiens_hsa006700.57104144
71Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.57022283
72Shigellosis_Homo sapiens_hsa051310.56669914
73Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.55063973
74Arginine and proline metabolism_Homo sapiens_hsa003300.54736491
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.53719617
76Vitamin B6 metabolism_Homo sapiens_hsa007500.53603993
77Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51913969
78NOD-like receptor signaling pathway_Homo sapiens_hsa046210.51667035
79Antigen processing and presentation_Homo sapiens_hsa046120.51501067
80Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.50470724
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50433532
82Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50300720
83Cysteine and methionine metabolism_Homo sapiens_hsa002700.50211678
84Sulfur relay system_Homo sapiens_hsa041220.47701324
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.47180493
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.45612871
87Measles_Homo sapiens_hsa051620.44250941
88Sphingolipid metabolism_Homo sapiens_hsa006000.43989497
89Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.43689605
90Drug metabolism - other enzymes_Homo sapiens_hsa009830.42720115
91Hematopoietic cell lineage_Homo sapiens_hsa046400.40864568
92Leishmaniasis_Homo sapiens_hsa051400.40001253
93beta-Alanine metabolism_Homo sapiens_hsa004100.39428625
94Other glycan degradation_Homo sapiens_hsa005110.38344881
95Pertussis_Homo sapiens_hsa051330.35648730
96Synaptic vesicle cycle_Homo sapiens_hsa047210.35591166
97Vitamin digestion and absorption_Homo sapiens_hsa049770.35400092
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.35222256
99Salmonella infection_Homo sapiens_hsa051320.35138722
100Galactose metabolism_Homo sapiens_hsa000520.33947624
101Tryptophan metabolism_Homo sapiens_hsa003800.33892375
102Fructose and mannose metabolism_Homo sapiens_hsa000510.33026278
103Systemic lupus erythematosus_Homo sapiens_hsa053220.31572715
104Fatty acid elongation_Homo sapiens_hsa000620.31465114
105Oocyte meiosis_Homo sapiens_hsa041140.30930875
106N-Glycan biosynthesis_Homo sapiens_hsa005100.30869668
107Butanoate metabolism_Homo sapiens_hsa006500.29763121
108Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.29323802
109* mRNA surveillance pathway_Homo sapiens_hsa030150.28891077
110Apoptosis_Homo sapiens_hsa042100.28847983
111Influenza A_Homo sapiens_hsa051640.28817937
112Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.28295650
113Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.26235344
114Tuberculosis_Homo sapiens_hsa051520.26097230
115Nitrogen metabolism_Homo sapiens_hsa009100.25682933
116Ether lipid metabolism_Homo sapiens_hsa005650.25423716
117Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.24025257
118Linoleic acid metabolism_Homo sapiens_hsa005910.23649783
119Phenylalanine metabolism_Homo sapiens_hsa003600.23421033
120Caffeine metabolism_Homo sapiens_hsa002320.20981059
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20506069
122Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.20342931
123Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.20229903
124Mineral absorption_Homo sapiens_hsa049780.19717545
125Malaria_Homo sapiens_hsa051440.19711499
126Steroid biosynthesis_Homo sapiens_hsa001000.19221343
127Lysosome_Homo sapiens_hsa041420.18007097
128Toll-like receptor signaling pathway_Homo sapiens_hsa046200.17426133
129African trypanosomiasis_Homo sapiens_hsa051430.15734828
130Arginine biosynthesis_Homo sapiens_hsa002200.13730892
131Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.13034923
132Viral carcinogenesis_Homo sapiens_hsa052030.12199093
133Glycosaminoglycan degradation_Homo sapiens_hsa005310.09016361
134Fatty acid metabolism_Homo sapiens_hsa012120.08524082
135Glycerophospholipid metabolism_Homo sapiens_hsa005640.05628310
136Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.04905925

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