

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of action potential (GO:0045760) | 7.91680444 |
| 2 | positive regulation of digestive system process (GO:0060456) | 7.59281551 |
| 3 | regulation of MHC class II biosynthetic process (GO:0045346) | 6.25226952 |
| 4 | protein K11-linked deubiquitination (GO:0035871) | 6.03294584 |
| 5 | regulation of action potential (GO:0098900) | 5.23403692 |
| 6 | sphingosine metabolic process (GO:0006670) | 5.19386954 |
| 7 | serotonin receptor signaling pathway (GO:0007210) | 4.98781480 |
| 8 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 4.80288117 |
| 9 | sphingoid metabolic process (GO:0046519) | 4.65549705 |
| 10 | diol metabolic process (GO:0034311) | 4.51136451 |
| 11 | cell wall macromolecule catabolic process (GO:0016998) | 4.44281075 |
| 12 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 4.43662404 |
| 13 | negative regulation of T-helper cell differentiation (GO:0045623) | 4.43662404 |
| 14 | negative regulation of heart rate (GO:0010459) | 3.96530964 |
| 15 | righting reflex (GO:0060013) | 3.89863269 |
| 16 | regulation of podosome assembly (GO:0071801) | 3.87395130 |
| 17 | positive regulation of granulocyte differentiation (GO:0030854) | 3.83578388 |
| 18 | positive regulation of steroid hormone secretion (GO:2000833) | 3.74544220 |
| 19 | regulation of glucocorticoid secretion (GO:2000849) | 3.69357618 |
| 20 | cell wall macromolecule metabolic process (GO:0044036) | 3.66341972 |
| 21 | positive regulation of organelle assembly (GO:1902117) | 3.65957340 |
| 22 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.63978081 |
| 23 | response to mercury ion (GO:0046689) | 3.58709114 |
| 24 | paraxial mesoderm development (GO:0048339) | 3.43854781 |
| 25 | positive regulation of renal sodium excretion (GO:0035815) | 3.42314648 |
| 26 | flavonoid metabolic process (GO:0009812) | 3.39858560 |
| 27 | regulation of immunoglobulin secretion (GO:0051023) | 3.39433416 |
| 28 | cellular ketone body metabolic process (GO:0046950) | 3.37240491 |
| 29 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.37204841 |
| 30 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.36823440 |
| 31 | DNA methylation involved in gamete generation (GO:0043046) | 3.33917618 |
| 32 | neuronal action potential propagation (GO:0019227) | 3.33251746 |
| 33 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.29696110 |
| 34 | regulation of chronic inflammatory response (GO:0002676) | 3.27588242 |
| 35 | reflex (GO:0060004) | 3.27239037 |
| 36 | T-helper cell differentiation (GO:0042093) | 3.27219989 |
| 37 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.27219989 |
| 38 | indolalkylamine metabolic process (GO:0006586) | 3.20812228 |
| 39 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 3.16843124 |
| 40 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.16518536 |
| 41 | negative regulation of acute inflammatory response (GO:0002674) | 3.16131824 |
| 42 | regulation of appetite (GO:0032098) | 3.13089210 |
| 43 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.10175280 |
| 44 | protein K63-linked deubiquitination (GO:0070536) | 3.08137158 |
| 45 | regulation of proton transport (GO:0010155) | 3.06358511 |
| 46 | meiotic chromosome segregation (GO:0045132) | 3.03354623 |
| 47 | photoreceptor cell maintenance (GO:0045494) | 3.01911393 |
| 48 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.01593101 |
| 49 | regulation of meiosis I (GO:0060631) | 3.01535126 |
| 50 | regulation of corticosteroid hormone secretion (GO:2000846) | 3.01112999 |
| 51 | protein-chromophore linkage (GO:0018298) | 3.00758734 |
| 52 | ketone body metabolic process (GO:1902224) | 3.00359882 |
| 53 | behavioral response to nicotine (GO:0035095) | 2.96985264 |
| 54 | somite rostral/caudal axis specification (GO:0032525) | 2.96133560 |
| 55 | regulation of cilium movement (GO:0003352) | 2.95671626 |
| 56 | establishment of protein localization to Golgi (GO:0072600) | 2.93812927 |
| 57 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.91253218 |
| 58 | regulation of protein glycosylation (GO:0060049) | 2.86618013 |
| 59 | positive regulation of vascular permeability (GO:0043117) | 2.85265495 |
| 60 | adaptation of signaling pathway (GO:0023058) | 2.85203425 |
| 61 | auditory receptor cell stereocilium organization (GO:0060088) | 2.84334414 |
| 62 | regulation of digestive system process (GO:0044058) | 2.81519713 |
| 63 | piRNA metabolic process (GO:0034587) | 2.80878581 |
| 64 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.80351165 |
| 65 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.80351165 |
| 66 | T cell differentiation involved in immune response (GO:0002292) | 2.80351165 |
| 67 | detection of light stimulus involved in visual perception (GO:0050908) | 2.79580089 |
| 68 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.79580089 |
| 69 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.78825544 |
| 70 | positive regulation of mitochondrial fission (GO:0090141) | 2.78519078 |
| 71 | DNA double-strand break processing (GO:0000729) | 2.72525165 |
| 72 | regulation of uterine smooth muscle contraction (GO:0070472) | 2.72254335 |
| 73 | nonmotile primary cilium assembly (GO:0035058) | 2.71261006 |
| 74 | neural tube formation (GO:0001841) | 2.67355033 |
| 75 | sulfation (GO:0051923) | 2.65331366 |
| 76 | retinal ganglion cell axon guidance (GO:0031290) | 2.64072733 |
| 77 | regulation of macrophage activation (GO:0043030) | 2.62069629 |
| 78 | thyroid hormone metabolic process (GO:0042403) | 2.61948694 |
| 79 | glycerophospholipid catabolic process (GO:0046475) | 2.60569429 |
| 80 | long-term memory (GO:0007616) | 2.60400774 |
| 81 | serotonin metabolic process (GO:0042428) | 2.60012212 |
| 82 | negative regulation of systemic arterial blood pressure (GO:0003085) | 2.59881409 |
| 83 | regulation of pigment cell differentiation (GO:0050932) | 2.58860544 |
| 84 | regulation of chemokine biosynthetic process (GO:0045073) | 2.57952748 |
| 85 | cytokine production involved in immune response (GO:0002367) | 2.57876996 |
| 86 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.56343181 |
| 87 | regulation of sarcomere organization (GO:0060297) | 2.56021980 |
| 88 | positive regulation of developmental pigmentation (GO:0048087) | 2.55111427 |
| 89 | mucosal immune response (GO:0002385) | 2.51997750 |
| 90 | protein targeting to Golgi (GO:0000042) | 2.49372083 |
| 91 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.48930357 |
| 92 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.47796958 |
| 93 | regulation of interleukin-13 production (GO:0032656) | 2.46861996 |
| 94 | urinary tract smooth muscle contraction (GO:0014848) | 2.46487374 |
| 95 | gamma-aminobutyric acid transport (GO:0015812) | 2.46341040 |
| 96 | inner ear receptor stereocilium organization (GO:0060122) | 2.46007209 |
| 97 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.45955550 |
| 98 | C-terminal protein amino acid modification (GO:0018410) | 2.45079490 |
| 99 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.44901199 |
| 100 | tachykinin receptor signaling pathway (GO:0007217) | 11.8315753 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.25509033 |
| 2 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.11554254 |
| 3 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.93872041 |
| 4 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.86667023 |
| 5 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.76493503 |
| 6 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.66648151 |
| 7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.56543384 |
| 8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.53426539 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.43818991 |
| 10 | FUS_26573619_Chip-Seq_HEK293_Human | 2.37383941 |
| 11 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.33817455 |
| 12 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.32893542 |
| 13 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.23094447 |
| 14 | P300_19829295_ChIP-Seq_ESCs_Human | 2.21914116 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.15677858 |
| 16 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.10376882 |
| 17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.98852920 |
| 18 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.97865448 |
| 19 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.95157636 |
| 20 | EWS_26573619_Chip-Seq_HEK293_Human | 1.95118349 |
| 21 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.92020357 |
| 22 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.83557809 |
| 23 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.79933961 |
| 24 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.77343495 |
| 25 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.76315168 |
| 26 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.75730299 |
| 27 | STAT3_23295773_ChIP-Seq_U87_Human | 1.75636852 |
| 28 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.69219951 |
| 29 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.67619310 |
| 30 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.67619310 |
| 31 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.66584086 |
| 32 | AR_25329375_ChIP-Seq_VCAP_Human | 1.59639089 |
| 33 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.59177530 |
| 34 | TCF4_23295773_ChIP-Seq_U87_Human | 1.58278604 |
| 35 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.56134779 |
| 36 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.54688253 |
| 37 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.54047855 |
| 38 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.52904457 |
| 39 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.50214864 |
| 40 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.49771100 |
| 41 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.47041162 |
| 42 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.46635539 |
| 43 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.45000348 |
| 44 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.44550094 |
| 45 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.44151367 |
| 46 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.40685251 |
| 47 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.40581162 |
| 48 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.39741413 |
| 49 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.39324094 |
| 50 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.38115593 |
| 51 | TP53_16413492_ChIP-PET_HCT116_Human | 1.37478381 |
| 52 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.37190459 |
| 53 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.36608117 |
| 54 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.34665253 |
| 55 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.32417219 |
| 56 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.31958590 |
| 57 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.29138744 |
| 58 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.29130318 |
| 59 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.28946555 |
| 60 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.27482478 |
| 61 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.26006912 |
| 62 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24804151 |
| 63 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.24314571 |
| 64 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.23010123 |
| 65 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.22436521 |
| 66 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.20656869 |
| 67 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.19806698 |
| 68 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.19477956 |
| 69 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.17650709 |
| 70 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.17650709 |
| 71 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.17647130 |
| 72 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.17414176 |
| 73 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.15096029 |
| 74 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.12978836 |
| 75 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.12775130 |
| 76 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.12654642 |
| 77 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.12617436 |
| 78 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.12033297 |
| 79 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.11414474 |
| 80 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.10521587 |
| 81 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.09386229 |
| 82 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09386229 |
| 83 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.05511970 |
| 84 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.05439754 |
| 85 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.05376311 |
| 86 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.04116417 |
| 87 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.03943073 |
| 88 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.03567818 |
| 89 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.03556523 |
| 90 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.02238895 |
| 91 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.02170615 |
| 92 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.00831281 |
| 93 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.00794180 |
| 94 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.00772943 |
| 95 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.99799498 |
| 96 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.99261103 |
| 97 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.98846680 |
| 98 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97886486 |
| 99 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97886486 |
| 100 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.97709435 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002837_dystrophic_cardiac_calcinosis | 4.46416763 |
| 2 | MP0010386_abnormal_urinary_bladder | 4.30725672 |
| 3 | MP0003136_yellow_coat_color | 3.50437265 |
| 4 | MP0003195_calcinosis | 3.46201175 |
| 5 | MP0001984_abnormal_olfaction | 3.08028239 |
| 6 | MP0005171_absent_coat_pigmentation | 2.94823130 |
| 7 | MP0001348_abnormal_lacrimal_gland | 2.92300644 |
| 8 | MP0005310_abnormal_salivary_gland | 2.81424226 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.81042707 |
| 10 | MP0001873_stomach_inflammation | 2.57255260 |
| 11 | MP0008872_abnormal_physiological_respon | 2.45955745 |
| 12 | MP0002735_abnormal_chemical_nociception | 2.44536658 |
| 13 | MP0002653_abnormal_ependyma_morphology | 2.41804356 |
| 14 | MP0000569_abnormal_digit_pigmentation | 2.36371932 |
| 15 | MP0009745_abnormal_behavioral_response | 2.30112972 |
| 16 | MP0000372_irregular_coat_pigmentation | 2.27512380 |
| 17 | MP0001529_abnormal_vocalization | 2.26123028 |
| 18 | MP0003646_muscle_fatigue | 2.25335458 |
| 19 | MP0002736_abnormal_nociception_after | 2.22707130 |
| 20 | MP0001968_abnormal_touch/_nociception | 2.18099132 |
| 21 | MP0002138_abnormal_hepatobiliary_system | 2.03974515 |
| 22 | MP0003880_abnormal_central_pattern | 2.01602746 |
| 23 | MP0005551_abnormal_eye_electrophysiolog | 1.99030748 |
| 24 | MP0002272_abnormal_nervous_system | 1.92341390 |
| 25 | MP0009046_muscle_twitch | 1.89836798 |
| 26 | MP0006276_abnormal_autonomic_nervous | 1.72264999 |
| 27 | MP0001970_abnormal_pain_threshold | 1.69453045 |
| 28 | MP0003879_abnormal_hair_cell | 1.68614183 |
| 29 | MP0005645_abnormal_hypothalamus_physiol | 1.67074703 |
| 30 | MP0001486_abnormal_startle_reflex | 1.66836141 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.62760682 |
| 32 | MP0003045_fibrosis | 1.60688498 |
| 33 | MP0004142_abnormal_muscle_tone | 1.60123913 |
| 34 | MP0002938_white_spotting | 1.59677714 |
| 35 | MP0002064_seizures | 1.57843351 |
| 36 | MP0002572_abnormal_emotion/affect_behav | 1.52698517 |
| 37 | MP0006082_CNS_inflammation | 1.52067794 |
| 38 | MP0004270_analgesia | 1.51920825 |
| 39 | MP0002876_abnormal_thyroid_physiology | 1.48694095 |
| 40 | MP0002734_abnormal_mechanical_nocicepti | 1.48106552 |
| 41 | MP0003635_abnormal_synaptic_transmissio | 1.45931624 |
| 42 | MP0003718_maternal_effect | 1.44684862 |
| 43 | MP0001501_abnormal_sleep_pattern | 1.41644184 |
| 44 | MP0004147_increased_porphyrin_level | 1.40543173 |
| 45 | MP0003890_abnormal_embryonic-extraembry | 1.39433188 |
| 46 | MP0005085_abnormal_gallbladder_physiolo | 1.37161087 |
| 47 | MP0005646_abnormal_pituitary_gland | 1.35968975 |
| 48 | MP0002277_abnormal_respiratory_mucosa | 1.30747166 |
| 49 | MP0005253_abnormal_eye_physiology | 1.27227981 |
| 50 | MP0004043_abnormal_pH_regulation | 1.18014008 |
| 51 | MP0009780_abnormal_chondrocyte_physiolo | 1.16149005 |
| 52 | MP0005670_abnormal_white_adipose | 1.14792133 |
| 53 | MP0005174_abnormal_tail_pigmentation | 1.08071749 |
| 54 | MP0003137_abnormal_impulse_conducting | 1.07993838 |
| 55 | MP0000427_abnormal_hair_cycle | 1.07867796 |
| 56 | MP0002557_abnormal_social/conspecific_i | 1.05255837 |
| 57 | MP0001502_abnormal_circadian_rhythm | 1.00594994 |
| 58 | MP0002063_abnormal_learning/memory/cond | 0.98869203 |
| 59 | MP0001756_abnormal_urination | 0.96999647 |
| 60 | MP0005395_other_phenotype | 0.95095451 |
| 61 | MP0000383_abnormal_hair_follicle | 0.92800229 |
| 62 | MP0002095_abnormal_skin_pigmentation | 0.92365609 |
| 63 | MP0004924_abnormal_behavior | 0.92285567 |
| 64 | MP0005386_behavior/neurological_phenoty | 0.92285567 |
| 65 | MP0002160_abnormal_reproductive_system | 0.91796676 |
| 66 | MP0004233_abnormal_muscle_weight | 0.91534357 |
| 67 | MP0004484_altered_response_of | 0.89746073 |
| 68 | MP0002067_abnormal_sensory_capabilities | 0.88583734 |
| 69 | MP0005075_abnormal_melanosome_morpholog | 0.88319790 |
| 70 | MP0004381_abnormal_hair_follicle | 0.88230001 |
| 71 | MP0002168_other_aberrant_phenotype | 0.88169552 |
| 72 | MP0002229_neurodegeneration | 0.87697588 |
| 73 | MP0002184_abnormal_innervation | 0.86676030 |
| 74 | MP0002254_reproductive_system_inflammat | 0.86218086 |
| 75 | MP0002733_abnormal_thermal_nociception | 0.84165309 |
| 76 | MP0008877_abnormal_DNA_methylation | 0.82471857 |
| 77 | MP0000015_abnormal_ear_pigmentation | 0.82291557 |
| 78 | MP0005389_reproductive_system_phenotype | 0.81464610 |
| 79 | MP0003183_abnormal_peptide_metabolism | 0.80406526 |
| 80 | MP0001440_abnormal_grooming_behavior | 0.79359864 |
| 81 | MP0000230_abnormal_systemic_arterial | 0.78999298 |
| 82 | MP0001764_abnormal_homeostasis | 0.78805562 |
| 83 | MP0005410_abnormal_fertilization | 0.78796924 |
| 84 | MP0000631_abnormal_neuroendocrine_gland | 0.78059004 |
| 85 | MP0000647_abnormal_sebaceous_gland | 0.77431296 |
| 86 | MP0002909_abnormal_adrenal_gland | 0.75531413 |
| 87 | MP0001986_abnormal_taste_sensitivity | 0.74292134 |
| 88 | MP0005332_abnormal_amino_acid | 0.73956630 |
| 89 | MP0000026_abnormal_inner_ear | 0.73800238 |
| 90 | MP0000639_abnormal_adrenal_gland | 0.71572841 |
| 91 | MP0000778_abnormal_nervous_system | 0.69112532 |
| 92 | MP0005448_abnormal_energy_balance | 0.68491346 |
| 93 | MP0010329_abnormal_lipoprotein_level | 0.67992580 |
| 94 | MP0002882_abnormal_neuron_morphology | 0.67821415 |
| 95 | MP0004133_heterotaxia | 0.66801264 |
| 96 | MP0005647_abnormal_sex_gland | 0.66673695 |
| 97 | MP0005195_abnormal_posterior_eye | 0.66633010 |
| 98 | MP0002752_abnormal_somatic_nervous | 0.65190062 |
| 99 | MP0003252_abnormal_bile_duct | 0.65115395 |
| 100 | MP0003787_abnormal_imprinting | 0.63477019 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Focal motor seizures (HP:0011153) | 4.37673108 |
| 2 | Pancreatic cysts (HP:0001737) | 4.16884315 |
| 3 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 3.99926311 |
| 4 | Large for gestational age (HP:0001520) | 3.82855842 |
| 5 | Amelogenesis imperfecta (HP:0000705) | 3.69898932 |
| 6 | Attenuation of retinal blood vessels (HP:0007843) | 3.55430495 |
| 7 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.53494818 |
| 8 | Type II lissencephaly (HP:0007260) | 3.39984829 |
| 9 | True hermaphroditism (HP:0010459) | 3.32819014 |
| 10 | Fibular aplasia (HP:0002990) | 3.07542851 |
| 11 | Congenital stationary night blindness (HP:0007642) | 3.02771934 |
| 12 | Pancreatic fibrosis (HP:0100732) | 2.94334909 |
| 13 | Pendular nystagmus (HP:0012043) | 2.92270202 |
| 14 | Medial flaring of the eyebrow (HP:0010747) | 2.90691480 |
| 15 | 3-Methylglutaconic aciduria (HP:0003535) | 2.88606212 |
| 16 | Hyperventilation (HP:0002883) | 2.87874543 |
| 17 | Decreased circulating renin level (HP:0003351) | 2.87634511 |
| 18 | Short tibia (HP:0005736) | 2.87403112 |
| 19 | Gaze-evoked nystagmus (HP:0000640) | 2.86229449 |
| 20 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.83989065 |
| 21 | Nephronophthisis (HP:0000090) | 2.83795139 |
| 22 | Intestinal atresia (HP:0011100) | 2.80371260 |
| 23 | Gait imbalance (HP:0002141) | 2.78971891 |
| 24 | Decreased central vision (HP:0007663) | 2.78634448 |
| 25 | Congenital sensorineural hearing impairment (HP:0008527) | 2.77649137 |
| 26 | Abolished electroretinogram (ERG) (HP:0000550) | 2.74580980 |
| 27 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.70462078 |
| 28 | Absent speech (HP:0001344) | 2.67272300 |
| 29 | Unilateral renal agenesis (HP:0000122) | 2.59498130 |
| 30 | Congenital primary aphakia (HP:0007707) | 2.58844414 |
| 31 | Dialeptic seizures (HP:0011146) | 2.56997137 |
| 32 | Broad-based gait (HP:0002136) | 2.53944513 |
| 33 | Abnormality of macular pigmentation (HP:0008002) | 2.51184791 |
| 34 | Cerebellar dysplasia (HP:0007033) | 2.51038760 |
| 35 | Focal seizures (HP:0007359) | 2.44593048 |
| 36 | Parakeratosis (HP:0001036) | 2.43200991 |
| 37 | Adactyly (HP:0009776) | 2.38256149 |
| 38 | Molar tooth sign on MRI (HP:0002419) | 2.36967667 |
| 39 | Abnormality of midbrain morphology (HP:0002418) | 2.36967667 |
| 40 | Retinitis pigmentosa (HP:0000510) | 2.28513756 |
| 41 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.26828309 |
| 42 | Nephrogenic diabetes insipidus (HP:0009806) | 2.26772851 |
| 43 | Abnormality of the renal medulla (HP:0100957) | 2.26088858 |
| 44 | Genital tract atresia (HP:0001827) | 2.25487873 |
| 45 | Vaginal atresia (HP:0000148) | 2.24747552 |
| 46 | Retinal dysplasia (HP:0007973) | 2.23528888 |
| 47 | Abnormality of the renal cortex (HP:0011035) | 2.21056649 |
| 48 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.20828060 |
| 49 | Abnormality of the labia minora (HP:0012880) | 2.08602838 |
| 50 | Colon cancer (HP:0003003) | 2.07548866 |
| 51 | Hematochezia (HP:0002573) | 2.07358033 |
| 52 | Lissencephaly (HP:0001339) | 2.06815403 |
| 53 | Constricted visual fields (HP:0001133) | 2.06561743 |
| 54 | Abnormal drinking behavior (HP:0030082) | 2.03457349 |
| 55 | Polydipsia (HP:0001959) | 2.03457349 |
| 56 | Calf muscle hypertrophy (HP:0008981) | 2.02733023 |
| 57 | Optic nerve hypoplasia (HP:0000609) | 1.96474774 |
| 58 | Abnormality of alanine metabolism (HP:0010916) | 1.95913473 |
| 59 | Hyperalaninemia (HP:0003348) | 1.95913473 |
| 60 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.95913473 |
| 61 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.95282812 |
| 62 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.94495349 |
| 63 | Opisthotonus (HP:0002179) | 1.92703833 |
| 64 | Erythroderma (HP:0001019) | 1.91933513 |
| 65 | Gastrointestinal atresia (HP:0002589) | 1.91146707 |
| 66 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.91124419 |
| 67 | Increased density of long bones (HP:0006392) | 1.90371339 |
| 68 | Cystic liver disease (HP:0006706) | 1.90357557 |
| 69 | Tubular atrophy (HP:0000092) | 1.90218403 |
| 70 | Poor coordination (HP:0002370) | 1.87835863 |
| 71 | Hypoplasia of the ulna (HP:0003022) | 1.87362887 |
| 72 | Progressive inability to walk (HP:0002505) | 1.86128479 |
| 73 | Genetic anticipation (HP:0003743) | 1.84242415 |
| 74 | Progressive cerebellar ataxia (HP:0002073) | 1.83767938 |
| 75 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.81850755 |
| 76 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.81850755 |
| 77 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.80657879 |
| 78 | Abnormality of dental color (HP:0011073) | 1.80225563 |
| 79 | Furrowed tongue (HP:0000221) | 1.79448996 |
| 80 | Hypokinesia (HP:0002375) | 1.78823129 |
| 81 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.78731788 |
| 82 | Astigmatism (HP:0000483) | 1.76975935 |
| 83 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.76748232 |
| 84 | Increased corneal curvature (HP:0100692) | 1.76274476 |
| 85 | Keratoconus (HP:0000563) | 1.76274476 |
| 86 | Hemiparesis (HP:0001269) | 1.75164113 |
| 87 | Hypoplasia of the uterus (HP:0000013) | 1.75102501 |
| 88 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.74246912 |
| 89 | Photophobia (HP:0000613) | 1.72216963 |
| 90 | Abnormality of the pons (HP:0007361) | 1.71224318 |
| 91 | Chronic hepatic failure (HP:0100626) | 1.71091129 |
| 92 | Short foot (HP:0001773) | 1.70777852 |
| 93 | Inability to walk (HP:0002540) | 1.70585856 |
| 94 | Oligodactyly (hands) (HP:0001180) | 1.69452655 |
| 95 | Clumsiness (HP:0002312) | 1.68724813 |
| 96 | Septo-optic dysplasia (HP:0100842) | 1.66525547 |
| 97 | Esophageal atresia (HP:0002032) | 1.66194004 |
| 98 | Type II diabetes mellitus (HP:0005978) | 1.65420065 |
| 99 | Male pseudohermaphroditism (HP:0000037) | 1.64326808 |
| 100 | Poikiloderma (HP:0001029) | 1.63798260 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.27603366 |
| 2 | LATS1 | 5.05014479 |
| 3 | STK38L | 4.41495037 |
| 4 | WNK3 | 3.70034001 |
| 5 | PBK | 3.38702744 |
| 6 | ZAK | 2.77542775 |
| 7 | PINK1 | 2.53264139 |
| 8 | EPHA3 | 2.28090016 |
| 9 | MAP4K2 | 2.20164599 |
| 10 | EIF2AK3 | 2.12827557 |
| 11 | MAPK13 | 2.10379763 |
| 12 | TNIK | 2.01561181 |
| 13 | LATS2 | 1.95688610 |
| 14 | ACVR1B | 1.86353769 |
| 15 | BMPR1B | 1.77612858 |
| 16 | EIF2AK1 | 1.69071096 |
| 17 | BRD4 | 1.65638494 |
| 18 | ADRBK2 | 1.62186254 |
| 19 | BCKDK | 1.59478809 |
| 20 | EPHA4 | 1.56996400 |
| 21 | STK3 | 1.55714706 |
| 22 | PRKD3 | 1.49229807 |
| 23 | BCR | 1.43925785 |
| 24 | CASK | 1.42563965 |
| 25 | CAMK1D | 1.38820911 |
| 26 | MAP3K4 | 1.38414421 |
| 27 | CSNK1A1L | 1.33597378 |
| 28 | NLK | 1.32228524 |
| 29 | PRKCE | 1.26195617 |
| 30 | SRPK1 | 1.17447888 |
| 31 | GRK1 | 1.15239054 |
| 32 | BLK | 1.14817662 |
| 33 | CSNK1G2 | 1.08504935 |
| 34 | STK38 | 1.06806619 |
| 35 | TRIM28 | 1.04776161 |
| 36 | CAMKK2 | 1.01077448 |
| 37 | TAOK3 | 0.99940040 |
| 38 | BRSK2 | 0.99555975 |
| 39 | MAP2K7 | 0.97256041 |
| 40 | MARK1 | 0.97035732 |
| 41 | CSNK1G3 | 0.95736975 |
| 42 | DAPK2 | 0.95387181 |
| 43 | STK39 | 0.90291864 |
| 44 | TNK2 | 0.86530358 |
| 45 | OXSR1 | 0.84310483 |
| 46 | PLK2 | 0.82041406 |
| 47 | RPS6KA4 | 0.81483982 |
| 48 | DYRK3 | 0.80482135 |
| 49 | ERBB3 | 0.77113676 |
| 50 | CAMK1G | 0.73364939 |
| 51 | PIK3CG | 0.72772857 |
| 52 | CSNK1G1 | 0.72296686 |
| 53 | GRK7 | 0.71109523 |
| 54 | SIK2 | 0.68183128 |
| 55 | NTRK3 | 0.67969828 |
| 56 | FER | 0.67692131 |
| 57 | NUAK1 | 0.67361733 |
| 58 | TXK | 0.67204004 |
| 59 | PAK3 | 0.66556483 |
| 60 | MKNK2 | 0.65311678 |
| 61 | NME1 | 0.65270475 |
| 62 | ADRBK1 | 0.64958216 |
| 63 | PRKCG | 0.56994209 |
| 64 | STK24 | 0.55545030 |
| 65 | MELK | 0.51636393 |
| 66 | EPHB1 | 0.51470977 |
| 67 | CAMK2A | 0.47590760 |
| 68 | STK4 | 0.46247137 |
| 69 | TGFBR1 | 0.45619276 |
| 70 | MKNK1 | 0.44184507 |
| 71 | INSRR | 0.43209436 |
| 72 | CAMK2D | 0.41181947 |
| 73 | PRKAA1 | 0.40057157 |
| 74 | CAMK4 | 0.39345188 |
| 75 | CSNK1A1 | 0.38941486 |
| 76 | MARK3 | 0.38355415 |
| 77 | PRKCZ | 0.36383682 |
| 78 | PRKAA2 | 0.36373143 |
| 79 | STK11 | 0.35332704 |
| 80 | NEK2 | 0.33225388 |
| 81 | NTRK2 | 0.33043152 |
| 82 | DYRK2 | 0.32296766 |
| 83 | CSNK1D | 0.29529234 |
| 84 | LIMK1 | 0.28996479 |
| 85 | ABL1 | 0.28874494 |
| 86 | CAMK2B | 0.27411457 |
| 87 | PRKD1 | 0.27399791 |
| 88 | TSSK6 | 0.26572839 |
| 89 | PRKACA | 0.26485719 |
| 90 | RPS6KA5 | 0.22005848 |
| 91 | NEK6 | 0.21564446 |
| 92 | TEC | 0.20632570 |
| 93 | CAMK2G | 0.20249756 |
| 94 | GSK3A | 0.20042357 |
| 95 | PLK1 | 0.19354851 |
| 96 | PKN1 | 0.17857179 |
| 97 | ITK | 0.17135078 |
| 98 | CHEK2 | 0.16829108 |
| 99 | NEK9 | 0.16682592 |
| 100 | PRKG1 | 0.16345737 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.09736392 |
| 2 | Phototransduction_Homo sapiens_hsa04744 | 2.99682407 |
| 3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.83206512 |
| 4 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.65350983 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.63147517 |
| 6 | Taste transduction_Homo sapiens_hsa04742 | 2.53906576 |
| 7 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.19909451 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.18365189 |
| 9 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.05002042 |
| 10 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.00025770 |
| 11 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.99405699 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.97059199 |
| 13 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.95245914 |
| 14 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.92016489 |
| 15 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.91821842 |
| 16 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.90177161 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.79130490 |
| 18 | Morphine addiction_Homo sapiens_hsa05032 | 1.71020598 |
| 19 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.62513443 |
| 20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.53861096 |
| 21 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.51541783 |
| 22 | Allograft rejection_Homo sapiens_hsa05330 | 1.50333638 |
| 23 | GABAergic synapse_Homo sapiens_hsa04727 | 1.48180501 |
| 24 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.41211888 |
| 25 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.40948494 |
| 26 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.40544223 |
| 27 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.32052619 |
| 28 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.30661228 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.28928213 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.26589926 |
| 31 | RNA polymerase_Homo sapiens_hsa03020 | 1.26144475 |
| 32 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.23544651 |
| 33 | ABC transporters_Homo sapiens_hsa02010 | 1.22531396 |
| 34 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.21061791 |
| 35 | Basal transcription factors_Homo sapiens_hsa03022 | 1.18077448 |
| 36 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.16342302 |
| 37 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.12428509 |
| 38 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.11651028 |
| 39 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.09167698 |
| 40 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.08358005 |
| 41 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.05382593 |
| 42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.04620964 |
| 43 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.04542017 |
| 44 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.02631033 |
| 45 | Salivary secretion_Homo sapiens_hsa04970 | 1.00793059 |
| 46 | Circadian rhythm_Homo sapiens_hsa04710 | 1.00672065 |
| 47 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.99508665 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.99380377 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.98698174 |
| 50 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.97660850 |
| 51 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.95005735 |
| 52 | Olfactory transduction_Homo sapiens_hsa04740 | 0.94966784 |
| 53 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.93248753 |
| 54 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.88111256 |
| 55 | Retinol metabolism_Homo sapiens_hsa00830 | 0.86896759 |
| 56 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.85926886 |
| 57 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.84527703 |
| 58 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.81730451 |
| 59 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.81172486 |
| 60 | Insulin secretion_Homo sapiens_hsa04911 | 0.76626164 |
| 61 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.76604916 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.74757588 |
| 63 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.73422651 |
| 64 | Circadian entrainment_Homo sapiens_hsa04713 | 0.73303445 |
| 65 | Long-term depression_Homo sapiens_hsa04730 | 0.72162924 |
| 66 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.72092712 |
| 67 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.68350954 |
| 68 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.67229537 |
| 69 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.64886189 |
| 70 | Homologous recombination_Homo sapiens_hsa03440 | 0.64432946 |
| 71 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.61532212 |
| 72 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.61037902 |
| 73 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.60566007 |
| 74 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.59129107 |
| 75 | Histidine metabolism_Homo sapiens_hsa00340 | 0.58999392 |
| 76 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.58860510 |
| 77 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.55472944 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54865732 |
| 79 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.53533762 |
| 80 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.52964003 |
| 81 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.52193043 |
| 82 | Huntingtons disease_Homo sapiens_hsa05016 | 0.51929994 |
| 83 | Renin secretion_Homo sapiens_hsa04924 | 0.50583827 |
| 84 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.50052825 |
| 85 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.49242903 |
| 86 | RNA degradation_Homo sapiens_hsa03018 | 0.48975801 |
| 87 | Purine metabolism_Homo sapiens_hsa00230 | 0.45914758 |
| 88 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.45558942 |
| 89 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.44911509 |
| 90 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.44441526 |
| 91 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.44153549 |
| 92 | Parkinsons disease_Homo sapiens_hsa05012 | 0.43840220 |
| 93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43711733 |
| 94 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.38378530 |
| 95 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.37610111 |
| 96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36536704 |
| 97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.36052618 |
| 98 | Cocaine addiction_Homo sapiens_hsa05030 | 0.36035788 |
| 99 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.35572658 |
| 100 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.32990490 |

