SSXP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of action potential (GO:0045760)7.91680444
2positive regulation of digestive system process (GO:0060456)7.59281551
3regulation of MHC class II biosynthetic process (GO:0045346)6.25226952
4protein K11-linked deubiquitination (GO:0035871)6.03294584
5regulation of action potential (GO:0098900)5.23403692
6sphingosine metabolic process (GO:0006670)5.19386954
7serotonin receptor signaling pathway (GO:0007210)4.98781480
8positive regulation of synaptic transmission, GABAergic (GO:0032230)4.80288117
9sphingoid metabolic process (GO:0046519)4.65549705
10diol metabolic process (GO:0034311)4.51136451
11cell wall macromolecule catabolic process (GO:0016998)4.44281075
12negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)4.43662404
13negative regulation of T-helper cell differentiation (GO:0045623)4.43662404
14negative regulation of heart rate (GO:0010459)3.96530964
15righting reflex (GO:0060013)3.89863269
16regulation of podosome assembly (GO:0071801)3.87395130
17positive regulation of granulocyte differentiation (GO:0030854)3.83578388
18positive regulation of steroid hormone secretion (GO:2000833)3.74544220
19regulation of glucocorticoid secretion (GO:2000849)3.69357618
20cell wall macromolecule metabolic process (GO:0044036)3.66341972
21positive regulation of organelle assembly (GO:1902117)3.65957340
22positive regulation of uterine smooth muscle contraction (GO:0070474)3.63978081
23response to mercury ion (GO:0046689)3.58709114
24paraxial mesoderm development (GO:0048339)3.43854781
25positive regulation of renal sodium excretion (GO:0035815)3.42314648
26flavonoid metabolic process (GO:0009812)3.39858560
27regulation of immunoglobulin secretion (GO:0051023)3.39433416
28cellular ketone body metabolic process (GO:0046950)3.37240491
29negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.37204841
30regulation of isotype switching to IgG isotypes (GO:0048302)3.36823440
31DNA methylation involved in gamete generation (GO:0043046)3.33917618
32neuronal action potential propagation (GO:0019227)3.33251746
33CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.29696110
34regulation of chronic inflammatory response (GO:0002676)3.27588242
35reflex (GO:0060004)3.27239037
36T-helper cell differentiation (GO:0042093)3.27219989
37CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.27219989
38indolalkylamine metabolic process (GO:0006586)3.20812228
39negative regulation of alpha-beta T cell differentiation (GO:0046639)3.16843124
40positive regulation of chemokine biosynthetic process (GO:0045080)3.16518536
41negative regulation of acute inflammatory response (GO:0002674)3.16131824
42regulation of appetite (GO:0032098)3.13089210
43gamma-aminobutyric acid signaling pathway (GO:0007214)3.10175280
44protein K63-linked deubiquitination (GO:0070536)3.08137158
45regulation of proton transport (GO:0010155)3.06358511
46meiotic chromosome segregation (GO:0045132)3.03354623
47photoreceptor cell maintenance (GO:0045494)3.01911393
48detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.01593101
49regulation of meiosis I (GO:0060631)3.01535126
50regulation of corticosteroid hormone secretion (GO:2000846)3.01112999
51protein-chromophore linkage (GO:0018298)3.00758734
52ketone body metabolic process (GO:1902224)3.00359882
53behavioral response to nicotine (GO:0035095)2.96985264
54somite rostral/caudal axis specification (GO:0032525)2.96133560
55regulation of cilium movement (GO:0003352)2.95671626
56establishment of protein localization to Golgi (GO:0072600)2.93812927
57G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.91253218
58regulation of protein glycosylation (GO:0060049)2.86618013
59positive regulation of vascular permeability (GO:0043117)2.85265495
60adaptation of signaling pathway (GO:0023058)2.85203425
61auditory receptor cell stereocilium organization (GO:0060088)2.84334414
62regulation of digestive system process (GO:0044058)2.81519713
63piRNA metabolic process (GO:0034587)2.80878581
64alpha-beta T cell differentiation involved in immune response (GO:0002293)2.80351165
65alpha-beta T cell activation involved in immune response (GO:0002287)2.80351165
66T cell differentiation involved in immune response (GO:0002292)2.80351165
67detection of light stimulus involved in visual perception (GO:0050908)2.79580089
68detection of light stimulus involved in sensory perception (GO:0050962)2.79580089
69lipopolysaccharide biosynthetic process (GO:0009103)2.78825544
70positive regulation of mitochondrial fission (GO:0090141)2.78519078
71DNA double-strand break processing (GO:0000729)2.72525165
72regulation of uterine smooth muscle contraction (GO:0070472)2.72254335
73nonmotile primary cilium assembly (GO:0035058)2.71261006
74neural tube formation (GO:0001841)2.67355033
75sulfation (GO:0051923)2.65331366
76retinal ganglion cell axon guidance (GO:0031290)2.64072733
77regulation of macrophage activation (GO:0043030)2.62069629
78thyroid hormone metabolic process (GO:0042403)2.61948694
79glycerophospholipid catabolic process (GO:0046475)2.60569429
80long-term memory (GO:0007616)2.60400774
81serotonin metabolic process (GO:0042428)2.60012212
82negative regulation of systemic arterial blood pressure (GO:0003085)2.59881409
83regulation of pigment cell differentiation (GO:0050932)2.58860544
84regulation of chemokine biosynthetic process (GO:0045073)2.57952748
85cytokine production involved in immune response (GO:0002367)2.57876996
86positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.56343181
87regulation of sarcomere organization (GO:0060297)2.56021980
88positive regulation of developmental pigmentation (GO:0048087)2.55111427
89mucosal immune response (GO:0002385)2.51997750
90protein targeting to Golgi (GO:0000042)2.49372083
91regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.48930357
92regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.47796958
93regulation of interleukin-13 production (GO:0032656)2.46861996
94urinary tract smooth muscle contraction (GO:0014848)2.46487374
95gamma-aminobutyric acid transport (GO:0015812)2.46341040
96inner ear receptor stereocilium organization (GO:0060122)2.46007209
97retrograde transport, vesicle recycling within Golgi (GO:0000301)2.45955550
98C-terminal protein amino acid modification (GO:0018410)2.45079490
99water-soluble vitamin biosynthetic process (GO:0042364)2.44901199
100tachykinin receptor signaling pathway (GO:0007217)11.8315753

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.25509033
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.11554254
3ZFP57_27257070_Chip-Seq_ESCs_Mouse2.93872041
4IGF1R_20145208_ChIP-Seq_DFB_Human2.86667023
5POU3F2_20337985_ChIP-ChIP_501MEL_Human2.76493503
6CTBP2_25329375_ChIP-Seq_LNCAP_Human2.66648151
7TAF15_26573619_Chip-Seq_HEK293_Human2.56543384
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.53426539
9ZNF274_21170338_ChIP-Seq_K562_Hela2.43818991
10FUS_26573619_Chip-Seq_HEK293_Human2.37383941
11CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.33817455
12CTBP1_25329375_ChIP-Seq_LNCAP_Human2.32893542
13PCGF2_27294783_Chip-Seq_ESCs_Mouse2.23094447
14P300_19829295_ChIP-Seq_ESCs_Human2.21914116
15VDR_22108803_ChIP-Seq_LS180_Human2.15677858
16ER_23166858_ChIP-Seq_MCF-7_Human2.10376882
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.98852920
18AR_21572438_ChIP-Seq_LNCaP_Human1.97865448
19SALL1_21062744_ChIP-ChIP_HESCs_Human1.95157636
20EWS_26573619_Chip-Seq_HEK293_Human1.95118349
21AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.92020357
22EZH2_22144423_ChIP-Seq_EOC_Human1.83557809
23RBPJ_22232070_ChIP-Seq_NCS_Mouse1.79933961
24SMAD4_21799915_ChIP-Seq_A2780_Human1.77343495
25PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.76315168
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.75730299
27STAT3_23295773_ChIP-Seq_U87_Human1.75636852
28PCGF2_27294783_Chip-Seq_NPCs_Mouse1.69219951
29CBP_20019798_ChIP-Seq_JUKART_Human1.67619310
30IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.67619310
31SUZ12_27294783_Chip-Seq_NPCs_Mouse1.66584086
32AR_25329375_ChIP-Seq_VCAP_Human1.59639089
33UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.59177530
34TCF4_23295773_ChIP-Seq_U87_Human1.58278604
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.56134779
36TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.54688253
37EZH2_27294783_Chip-Seq_NPCs_Mouse1.54047855
38PIAS1_25552417_ChIP-Seq_VCAP_Human1.52904457
39NFE2_27457419_Chip-Seq_LIVER_Mouse1.50214864
40OCT4_21477851_ChIP-Seq_ESCs_Mouse1.49771100
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.47041162
42MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.46635539
43NR3C1_21868756_ChIP-Seq_MCF10A_Human1.45000348
44NANOG_18555785_Chip-Seq_ESCs_Mouse1.44550094
45BCAT_22108803_ChIP-Seq_LS180_Human1.44151367
46FLI1_21867929_ChIP-Seq_TH2_Mouse1.40685251
47SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40581162
48CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.39741413
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39324094
50CRX_20693478_ChIP-Seq_RETINA_Mouse1.38115593
51TP53_16413492_ChIP-PET_HCT116_Human1.37478381
52KLF5_20875108_ChIP-Seq_MESCs_Mouse1.37190459
53MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.36608117
54HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.34665253
55TCF4_22108803_ChIP-Seq_LS180_Human1.32417219
56EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.31958590
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.29138744
58PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29130318
59REST_21632747_ChIP-Seq_MESCs_Mouse1.28946555
60RUNX2_22187159_ChIP-Seq_PCA_Human1.27482478
61OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26006912
62TP53_22573176_ChIP-Seq_HFKS_Human1.24804151
63P53_22387025_ChIP-Seq_ESCs_Mouse1.24314571
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.23010123
65SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.22436521
66PRDM14_20953172_ChIP-Seq_ESCs_Human1.20656869
67TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.19806698
68STAT3_18555785_Chip-Seq_ESCs_Mouse1.19477956
69SOX2_19829295_ChIP-Seq_ESCs_Human1.17650709
70NANOG_19829295_ChIP-Seq_ESCs_Human1.17650709
71TP53_18474530_ChIP-ChIP_U2OS_Human1.17647130
72SMAD4_21741376_ChIP-Seq_EPCs_Human1.17414176
73E2F1_18555785_Chip-Seq_ESCs_Mouse1.15096029
74P300_18555785_Chip-Seq_ESCs_Mouse1.12978836
75CMYC_18555785_Chip-Seq_ESCs_Mouse1.12775130
76EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12654642
77TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.12617436
78GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.12033297
79DROSHA_22980978_ChIP-Seq_HELA_Human1.11414474
80EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.10521587
81POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09386229
82TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09386229
83SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05511970
84GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.05439754
85CDX2_22108803_ChIP-Seq_LS180_Human1.05376311
86EGR1_23403033_ChIP-Seq_LIVER_Mouse1.04116417
87KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.03943073
88NMYC_18555785_Chip-Seq_ESCs_Mouse1.03567818
89SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.03556523
90SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.02238895
91SMAD_19615063_ChIP-ChIP_OVARY_Human1.02170615
92HOXB7_26014856_ChIP-Seq_BT474_Human1.00831281
93OCT4_18555785_Chip-Seq_ESCs_Mouse1.00794180
94SOX2_18555785_Chip-Seq_ESCs_Mouse1.00772943
95TAL1_26923725_Chip-Seq_HPCs_Mouse0.99799498
96NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.99261103
97BMI1_23680149_ChIP-Seq_NPCS_Mouse0.98846680
98FOXA1_25329375_ChIP-Seq_VCAP_Human0.97886486
99FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97886486
100CBX2_27304074_Chip-Seq_ESCs_Mouse0.97709435

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis4.46416763
2MP0010386_abnormal_urinary_bladder4.30725672
3MP0003136_yellow_coat_color3.50437265
4MP0003195_calcinosis3.46201175
5MP0001984_abnormal_olfaction3.08028239
6MP0005171_absent_coat_pigmentation2.94823130
7MP0001348_abnormal_lacrimal_gland2.92300644
8MP0005310_abnormal_salivary_gland2.81424226
9MP0008875_abnormal_xenobiotic_pharmacok2.81042707
10MP0001873_stomach_inflammation2.57255260
11MP0008872_abnormal_physiological_respon2.45955745
12MP0002735_abnormal_chemical_nociception2.44536658
13MP0002653_abnormal_ependyma_morphology2.41804356
14MP0000569_abnormal_digit_pigmentation2.36371932
15MP0009745_abnormal_behavioral_response2.30112972
16MP0000372_irregular_coat_pigmentation2.27512380
17MP0001529_abnormal_vocalization2.26123028
18MP0003646_muscle_fatigue2.25335458
19MP0002736_abnormal_nociception_after2.22707130
20MP0001968_abnormal_touch/_nociception2.18099132
21MP0002138_abnormal_hepatobiliary_system2.03974515
22MP0003880_abnormal_central_pattern2.01602746
23MP0005551_abnormal_eye_electrophysiolog1.99030748
24MP0002272_abnormal_nervous_system1.92341390
25MP0009046_muscle_twitch1.89836798
26MP0006276_abnormal_autonomic_nervous1.72264999
27MP0001970_abnormal_pain_threshold1.69453045
28MP0003879_abnormal_hair_cell1.68614183
29MP0005645_abnormal_hypothalamus_physiol1.67074703
30MP0001486_abnormal_startle_reflex1.66836141
31MP0006072_abnormal_retinal_apoptosis1.62760682
32MP0003045_fibrosis1.60688498
33MP0004142_abnormal_muscle_tone1.60123913
34MP0002938_white_spotting1.59677714
35MP0002064_seizures1.57843351
36MP0002572_abnormal_emotion/affect_behav1.52698517
37MP0006082_CNS_inflammation1.52067794
38MP0004270_analgesia1.51920825
39MP0002876_abnormal_thyroid_physiology1.48694095
40MP0002734_abnormal_mechanical_nocicepti1.48106552
41MP0003635_abnormal_synaptic_transmissio1.45931624
42MP0003718_maternal_effect1.44684862
43MP0001501_abnormal_sleep_pattern1.41644184
44MP0004147_increased_porphyrin_level1.40543173
45MP0003890_abnormal_embryonic-extraembry1.39433188
46MP0005085_abnormal_gallbladder_physiolo1.37161087
47MP0005646_abnormal_pituitary_gland1.35968975
48MP0002277_abnormal_respiratory_mucosa1.30747166
49MP0005253_abnormal_eye_physiology1.27227981
50MP0004043_abnormal_pH_regulation1.18014008
51MP0009780_abnormal_chondrocyte_physiolo1.16149005
52MP0005670_abnormal_white_adipose1.14792133
53MP0005174_abnormal_tail_pigmentation1.08071749
54MP0003137_abnormal_impulse_conducting1.07993838
55MP0000427_abnormal_hair_cycle1.07867796
56MP0002557_abnormal_social/conspecific_i1.05255837
57MP0001502_abnormal_circadian_rhythm1.00594994
58MP0002063_abnormal_learning/memory/cond0.98869203
59MP0001756_abnormal_urination0.96999647
60MP0005395_other_phenotype0.95095451
61MP0000383_abnormal_hair_follicle0.92800229
62MP0002095_abnormal_skin_pigmentation0.92365609
63MP0004924_abnormal_behavior0.92285567
64MP0005386_behavior/neurological_phenoty0.92285567
65MP0002160_abnormal_reproductive_system0.91796676
66MP0004233_abnormal_muscle_weight0.91534357
67MP0004484_altered_response_of0.89746073
68MP0002067_abnormal_sensory_capabilities0.88583734
69MP0005075_abnormal_melanosome_morpholog0.88319790
70MP0004381_abnormal_hair_follicle0.88230001
71MP0002168_other_aberrant_phenotype0.88169552
72MP0002229_neurodegeneration0.87697588
73MP0002184_abnormal_innervation0.86676030
74MP0002254_reproductive_system_inflammat0.86218086
75MP0002733_abnormal_thermal_nociception0.84165309
76MP0008877_abnormal_DNA_methylation0.82471857
77MP0000015_abnormal_ear_pigmentation0.82291557
78MP0005389_reproductive_system_phenotype0.81464610
79MP0003183_abnormal_peptide_metabolism0.80406526
80MP0001440_abnormal_grooming_behavior0.79359864
81MP0000230_abnormal_systemic_arterial0.78999298
82MP0001764_abnormal_homeostasis0.78805562
83MP0005410_abnormal_fertilization0.78796924
84MP0000631_abnormal_neuroendocrine_gland0.78059004
85MP0000647_abnormal_sebaceous_gland0.77431296
86MP0002909_abnormal_adrenal_gland0.75531413
87MP0001986_abnormal_taste_sensitivity0.74292134
88MP0005332_abnormal_amino_acid0.73956630
89MP0000026_abnormal_inner_ear0.73800238
90MP0000639_abnormal_adrenal_gland0.71572841
91MP0000778_abnormal_nervous_system0.69112532
92MP0005448_abnormal_energy_balance0.68491346
93MP0010329_abnormal_lipoprotein_level0.67992580
94MP0002882_abnormal_neuron_morphology0.67821415
95MP0004133_heterotaxia0.66801264
96MP0005647_abnormal_sex_gland0.66673695
97MP0005195_abnormal_posterior_eye0.66633010
98MP0002752_abnormal_somatic_nervous0.65190062
99MP0003252_abnormal_bile_duct0.65115395
100MP0003787_abnormal_imprinting0.63477019

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.37673108
2Pancreatic cysts (HP:0001737)4.16884315
3Aplasia/Hypoplasia of the tibia (HP:0005772)3.99926311
4Large for gestational age (HP:0001520)3.82855842
5Amelogenesis imperfecta (HP:0000705)3.69898932
6Attenuation of retinal blood vessels (HP:0007843)3.55430495
7Bony spicule pigmentary retinopathy (HP:0007737)3.53494818
8Type II lissencephaly (HP:0007260)3.39984829
9True hermaphroditism (HP:0010459)3.32819014
10Fibular aplasia (HP:0002990)3.07542851
11Congenital stationary night blindness (HP:0007642)3.02771934
12Pancreatic fibrosis (HP:0100732)2.94334909
13Pendular nystagmus (HP:0012043)2.92270202
14Medial flaring of the eyebrow (HP:0010747)2.90691480
153-Methylglutaconic aciduria (HP:0003535)2.88606212
16Hyperventilation (HP:0002883)2.87874543
17Decreased circulating renin level (HP:0003351)2.87634511
18Short tibia (HP:0005736)2.87403112
19Gaze-evoked nystagmus (HP:0000640)2.86229449
20Absent rod-and cone-mediated responses on ERG (HP:0007688)2.83989065
21Nephronophthisis (HP:0000090)2.83795139
22Intestinal atresia (HP:0011100)2.80371260
23Gait imbalance (HP:0002141)2.78971891
24Decreased central vision (HP:0007663)2.78634448
25Congenital sensorineural hearing impairment (HP:0008527)2.77649137
26Abolished electroretinogram (ERG) (HP:0000550)2.74580980
27Abnormal rod and cone electroretinograms (HP:0008323)2.70462078
28Absent speech (HP:0001344)2.67272300
29Unilateral renal agenesis (HP:0000122)2.59498130
30Congenital primary aphakia (HP:0007707)2.58844414
31Dialeptic seizures (HP:0011146)2.56997137
32Broad-based gait (HP:0002136)2.53944513
33Abnormality of macular pigmentation (HP:0008002)2.51184791
34Cerebellar dysplasia (HP:0007033)2.51038760
35Focal seizures (HP:0007359)2.44593048
36Parakeratosis (HP:0001036)2.43200991
37Adactyly (HP:0009776)2.38256149
38Molar tooth sign on MRI (HP:0002419)2.36967667
39Abnormality of midbrain morphology (HP:0002418)2.36967667
40Retinitis pigmentosa (HP:0000510)2.28513756
41Aplasia/Hypoplasia of the uvula (HP:0010293)2.26828309
42Nephrogenic diabetes insipidus (HP:0009806)2.26772851
43Abnormality of the renal medulla (HP:0100957)2.26088858
44Genital tract atresia (HP:0001827)2.25487873
45Vaginal atresia (HP:0000148)2.24747552
46Retinal dysplasia (HP:0007973)2.23528888
47Abnormality of the renal cortex (HP:0011035)2.21056649
48Decreased electroretinogram (ERG) amplitude (HP:0000654)2.20828060
49Abnormality of the labia minora (HP:0012880)2.08602838
50Colon cancer (HP:0003003)2.07548866
51Hematochezia (HP:0002573)2.07358033
52Lissencephaly (HP:0001339)2.06815403
53Constricted visual fields (HP:0001133)2.06561743
54Abnormal drinking behavior (HP:0030082)2.03457349
55Polydipsia (HP:0001959)2.03457349
56Calf muscle hypertrophy (HP:0008981)2.02733023
57Optic nerve hypoplasia (HP:0000609)1.96474774
58Abnormality of alanine metabolism (HP:0010916)1.95913473
59Hyperalaninemia (HP:0003348)1.95913473
60Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.95913473
61Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.95282812
62Abnormality of the phalanges of the 2nd finger (HP:0009541)1.94495349
63Opisthotonus (HP:0002179)1.92703833
64Erythroderma (HP:0001019)1.91933513
65Gastrointestinal atresia (HP:0002589)1.91146707
66Aplasia/hypoplasia of the uterus (HP:0008684)1.91124419
67Increased density of long bones (HP:0006392)1.90371339
68Cystic liver disease (HP:0006706)1.90357557
69Tubular atrophy (HP:0000092)1.90218403
70Poor coordination (HP:0002370)1.87835863
71Hypoplasia of the ulna (HP:0003022)1.87362887
72Progressive inability to walk (HP:0002505)1.86128479
73Genetic anticipation (HP:0003743)1.84242415
74Progressive cerebellar ataxia (HP:0002073)1.83767938
75Degeneration of the lateral corticospinal tracts (HP:0002314)1.81850755
76Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.81850755
77Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.80657879
78Abnormality of dental color (HP:0011073)1.80225563
79Furrowed tongue (HP:0000221)1.79448996
80Hypokinesia (HP:0002375)1.78823129
81Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.78731788
82Astigmatism (HP:0000483)1.76975935
83Aplasia/Hypoplasia of the ulna (HP:0006495)1.76748232
84Increased corneal curvature (HP:0100692)1.76274476
85Keratoconus (HP:0000563)1.76274476
86Hemiparesis (HP:0001269)1.75164113
87Hypoplasia of the uterus (HP:0000013)1.75102501
88Muscle hypertrophy of the lower extremities (HP:0008968)1.74246912
89Photophobia (HP:0000613)1.72216963
90Abnormality of the pons (HP:0007361)1.71224318
91Chronic hepatic failure (HP:0100626)1.71091129
92Short foot (HP:0001773)1.70777852
93Inability to walk (HP:0002540)1.70585856
94Oligodactyly (hands) (HP:0001180)1.69452655
95Clumsiness (HP:0002312)1.68724813
96Septo-optic dysplasia (HP:0100842)1.66525547
97Esophageal atresia (HP:0002032)1.66194004
98Type II diabetes mellitus (HP:0005978)1.65420065
99Male pseudohermaphroditism (HP:0000037)1.64326808
100Poikiloderma (HP:0001029)1.63798260

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.27603366
2LATS15.05014479
3STK38L4.41495037
4WNK33.70034001
5PBK3.38702744
6ZAK2.77542775
7PINK12.53264139
8EPHA32.28090016
9MAP4K22.20164599
10EIF2AK32.12827557
11MAPK132.10379763
12TNIK2.01561181
13LATS21.95688610
14ACVR1B1.86353769
15BMPR1B1.77612858
16EIF2AK11.69071096
17BRD41.65638494
18ADRBK21.62186254
19BCKDK1.59478809
20EPHA41.56996400
21STK31.55714706
22PRKD31.49229807
23BCR1.43925785
24CASK1.42563965
25CAMK1D1.38820911
26MAP3K41.38414421
27CSNK1A1L1.33597378
28NLK1.32228524
29PRKCE1.26195617
30SRPK11.17447888
31GRK11.15239054
32BLK1.14817662
33CSNK1G21.08504935
34STK381.06806619
35TRIM281.04776161
36CAMKK21.01077448
37TAOK30.99940040
38BRSK20.99555975
39MAP2K70.97256041
40MARK10.97035732
41CSNK1G30.95736975
42DAPK20.95387181
43STK390.90291864
44TNK20.86530358
45OXSR10.84310483
46PLK20.82041406
47RPS6KA40.81483982
48DYRK30.80482135
49ERBB30.77113676
50CAMK1G0.73364939
51PIK3CG0.72772857
52CSNK1G10.72296686
53GRK70.71109523
54SIK20.68183128
55NTRK30.67969828
56FER0.67692131
57NUAK10.67361733
58TXK0.67204004
59PAK30.66556483
60MKNK20.65311678
61NME10.65270475
62ADRBK10.64958216
63PRKCG0.56994209
64STK240.55545030
65MELK0.51636393
66EPHB10.51470977
67CAMK2A0.47590760
68STK40.46247137
69TGFBR10.45619276
70MKNK10.44184507
71INSRR0.43209436
72CAMK2D0.41181947
73PRKAA10.40057157
74CAMK40.39345188
75CSNK1A10.38941486
76MARK30.38355415
77PRKCZ0.36383682
78PRKAA20.36373143
79STK110.35332704
80NEK20.33225388
81NTRK20.33043152
82DYRK20.32296766
83CSNK1D0.29529234
84LIMK10.28996479
85ABL10.28874494
86CAMK2B0.27411457
87PRKD10.27399791
88TSSK60.26572839
89PRKACA0.26485719
90RPS6KA50.22005848
91NEK60.21564446
92TEC0.20632570
93CAMK2G0.20249756
94GSK3A0.20042357
95PLK10.19354851
96PKN10.17857179
97ITK0.17135078
98CHEK20.16829108
99NEK90.16682592
100PRKG10.16345737

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.09736392
2Phototransduction_Homo sapiens_hsa047442.99682407
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.83206512
4Butanoate metabolism_Homo sapiens_hsa006502.65350983
5Asthma_Homo sapiens_hsa053102.63147517
6Taste transduction_Homo sapiens_hsa047422.53906576
7Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.19909451
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.18365189
9Propanoate metabolism_Homo sapiens_hsa006402.05002042
10Selenocompound metabolism_Homo sapiens_hsa004502.00025770
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.99405699
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.97059199
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.95245914
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.92016489
15Maturity onset diabetes of the young_Homo sapiens_hsa049501.91821842
16Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.90177161
17Protein export_Homo sapiens_hsa030601.79130490
18Morphine addiction_Homo sapiens_hsa050321.71020598
19Tryptophan metabolism_Homo sapiens_hsa003801.62513443
20Linoleic acid metabolism_Homo sapiens_hsa005911.53861096
21Sphingolipid metabolism_Homo sapiens_hsa006001.51541783
22Allograft rejection_Homo sapiens_hsa053301.50333638
23GABAergic synapse_Homo sapiens_hsa047271.48180501
24Autoimmune thyroid disease_Homo sapiens_hsa053201.41211888
25Glutamatergic synapse_Homo sapiens_hsa047241.40948494
26Steroid hormone biosynthesis_Homo sapiens_hsa001401.40544223
27Dorso-ventral axis formation_Homo sapiens_hsa043201.32052619
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.30661228
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28928213
30Nitrogen metabolism_Homo sapiens_hsa009101.26589926
31RNA polymerase_Homo sapiens_hsa030201.26144475
32Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.23544651
33ABC transporters_Homo sapiens_hsa020101.22531396
34Serotonergic synapse_Homo sapiens_hsa047261.21061791
35Basal transcription factors_Homo sapiens_hsa030221.18077448
36Calcium signaling pathway_Homo sapiens_hsa040201.16342302
37Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.12428509
38Primary bile acid biosynthesis_Homo sapiens_hsa001201.11651028
39Regulation of autophagy_Homo sapiens_hsa041401.09167698
40Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.08358005
41Vitamin B6 metabolism_Homo sapiens_hsa007501.05382593
42Ether lipid metabolism_Homo sapiens_hsa005651.04620964
43Caffeine metabolism_Homo sapiens_hsa002321.04542017
44Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.02631033
45Salivary secretion_Homo sapiens_hsa049701.00793059
46Circadian rhythm_Homo sapiens_hsa047101.00672065
47Oxidative phosphorylation_Homo sapiens_hsa001900.99508665
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.99380377
49Peroxisome_Homo sapiens_hsa041460.98698174
50Fanconi anemia pathway_Homo sapiens_hsa034600.97660850
51Synaptic vesicle cycle_Homo sapiens_hsa047210.95005735
52Olfactory transduction_Homo sapiens_hsa047400.94966784
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93248753
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.88111256
55Retinol metabolism_Homo sapiens_hsa008300.86896759
56Arachidonic acid metabolism_Homo sapiens_hsa005900.85926886
57Collecting duct acid secretion_Homo sapiens_hsa049660.84527703
58One carbon pool by folate_Homo sapiens_hsa006700.81730451
59Ovarian steroidogenesis_Homo sapiens_hsa049130.81172486
60Insulin secretion_Homo sapiens_hsa049110.76626164
61Cysteine and methionine metabolism_Homo sapiens_hsa002700.76604916
62Chemical carcinogenesis_Homo sapiens_hsa052040.74757588
63Glycerolipid metabolism_Homo sapiens_hsa005610.73422651
64Circadian entrainment_Homo sapiens_hsa047130.73303445
65Long-term depression_Homo sapiens_hsa047300.72162924
66Glutathione metabolism_Homo sapiens_hsa004800.72092712
67Sulfur metabolism_Homo sapiens_hsa009200.68350954
68Cyanoamino acid metabolism_Homo sapiens_hsa004600.67229537
69Fatty acid degradation_Homo sapiens_hsa000710.64886189
70Homologous recombination_Homo sapiens_hsa034400.64432946
71Vitamin digestion and absorption_Homo sapiens_hsa049770.61532212
72Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.61037902
73Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.60566007
74Thyroid hormone synthesis_Homo sapiens_hsa049180.59129107
75Histidine metabolism_Homo sapiens_hsa003400.58999392
76Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58860510
77Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.55472944
78Metabolic pathways_Homo sapiens_hsa011000.54865732
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.53533762
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.52964003
81N-Glycan biosynthesis_Homo sapiens_hsa005100.52193043
82Huntingtons disease_Homo sapiens_hsa050160.51929994
83Renin secretion_Homo sapiens_hsa049240.50583827
84Fatty acid metabolism_Homo sapiens_hsa012120.50052825
85Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49242903
86RNA degradation_Homo sapiens_hsa030180.48975801
87Purine metabolism_Homo sapiens_hsa002300.45914758
88Arginine and proline metabolism_Homo sapiens_hsa003300.45558942
89Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44911509
90Starch and sucrose metabolism_Homo sapiens_hsa005000.44441526
91cAMP signaling pathway_Homo sapiens_hsa040240.44153549
92Parkinsons disease_Homo sapiens_hsa050120.43840220
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43711733
94Steroid biosynthesis_Homo sapiens_hsa001000.38378530
95Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.37610111
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36536704
97Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36052618
98Cocaine addiction_Homo sapiens_hsa050300.36035788
99Dopaminergic synapse_Homo sapiens_hsa047280.35572658
100Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32990490

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »