ST13P20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1keratinization (GO:0031424)6.17519147
2response to pheromone (GO:0019236)6.09821615
3behavioral response to nicotine (GO:0035095)5.86117077
4chaperone mediated protein folding requiring cofactor (GO:0051085)5.48285680
5protein refolding (GO:0042026)5.12679757
6somite development (GO:0061053)4.21838386
7pyrimidine nucleobase catabolic process (GO:0006208)4.15444482
8opioid receptor signaling pathway (GO:0038003)4.08155476
9DNA double-strand break processing (GO:0000729)4.04316369
10cellular response to interferon-beta (GO:0035458)3.97700909
11L-fucose metabolic process (GO:0042354)3.95075395
12L-fucose catabolic process (GO:0042355)3.95075395
13fucose catabolic process (GO:0019317)3.95075395
14mitochondrial respiratory chain complex I assembly (GO:0032981)3.89303922
15NADH dehydrogenase complex assembly (GO:0010257)3.89303922
16mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.89303922
17DNA deamination (GO:0045006)3.78987673
18replication fork processing (GO:0031297)3.59095857
19establishment of protein localization to mitochondrial membrane (GO:0090151)3.57731584
20DNA damage response, detection of DNA damage (GO:0042769)3.51559765
21hypothalamus development (GO:0021854)3.40930597
22negative regulation of transcription regulatory region DNA binding (GO:2000678)3.37882077
23ubiquinone biosynthetic process (GO:0006744)3.37733454
24intraciliary transport (GO:0042073)3.35635131
25proteasome assembly (GO:0043248)3.33459213
26telomere maintenance via telomerase (GO:0007004)3.33340647
27energy coupled proton transport, down electrochemical gradient (GO:0015985)3.31642706
28ATP synthesis coupled proton transport (GO:0015986)3.31642706
29positive regulation of humoral immune response (GO:0002922)3.30600822
30nucleobase catabolic process (GO:0046113)3.30026598
31cardiovascular system development (GO:0072358)3.29253527
32activated T cell proliferation (GO:0050798)3.28423170
33postsynaptic membrane organization (GO:0001941)3.28111674
34endoderm formation (GO:0001706)3.23637239
35water-soluble vitamin biosynthetic process (GO:0042364)3.20680978
36spinal cord development (GO:0021510)3.19551582
37nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.18852354
38exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.17675155
39peptidyl-histidine modification (GO:0018202)3.17417960
40phosphatidylinositol acyl-chain remodeling (GO:0036149)3.14514674
41regulation of non-canonical Wnt signaling pathway (GO:2000050)3.13585048
42ubiquinone metabolic process (GO:0006743)3.11812329
43phosphatidylserine acyl-chain remodeling (GO:0036150)3.09879881
44protein complex biogenesis (GO:0070271)3.08129466
45positive regulation of gastrulation (GO:2000543)3.07111365
46tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.04300293
47RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.04300293
48protein neddylation (GO:0045116)3.03852885
49protein localization to cilium (GO:0061512)3.03805327
50mitochondrial respiratory chain complex assembly (GO:0033108)2.99143258
51head development (GO:0060322)2.96230112
52positive regulation of defense response to virus by host (GO:0002230)2.93697054
53regulation of oxidative phosphorylation (GO:0002082)2.93228673
54regulation of response to tumor cell (GO:0002834)2.85232194
55positive regulation of response to tumor cell (GO:0002836)2.85232194
56positive regulation of immune response to tumor cell (GO:0002839)2.85232194
57regulation of immune response to tumor cell (GO:0002837)2.85232194
58ncRNA 3-end processing (GO:0043628)2.82937724
59mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.82666613
60regulation of cellular respiration (GO:0043457)2.82446518
61response to misfolded protein (GO:0051788)2.81710412
62detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.79184930
63reciprocal DNA recombination (GO:0035825)2.77613200
64reciprocal meiotic recombination (GO:0007131)2.77613200
65spinal cord association neuron differentiation (GO:0021527)2.77551269
66epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.75226696
67DNA catabolic process, exonucleolytic (GO:0000738)2.74329783
68photoreceptor cell development (GO:0042461)2.74131188
69L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.74069109
70spliceosomal complex assembly (GO:0000245)2.70446896
71epithelial cilium movement (GO:0003351)2.68345961
72olfactory bulb development (GO:0021772)2.67826543
73regulation of centriole replication (GO:0046599)2.67408053
74synaptic transmission, cholinergic (GO:0007271)2.65917103
75N-glycan processing (GO:0006491)2.65892526
76quinone biosynthetic process (GO:1901663)2.64603364
77mannosylation (GO:0097502)2.64497165
78superoxide anion generation (GO:0042554)2.61955917
79rRNA modification (GO:0000154)2.61327102
80plasma membrane fusion (GO:0045026)2.60751775
81transcription elongation from RNA polymerase I promoter (GO:0006362)2.60608308
82positive regulation of response to oxidative stress (GO:1902884)2.60050465
83positive regulation of cellular response to oxidative stress (GO:1900409)2.60050465
84termination of RNA polymerase I transcription (GO:0006363)2.59398026
85negative regulation of inclusion body assembly (GO:0090084)2.59024209
86regulation of MHC class I biosynthetic process (GO:0045343)2.58766624
87tRNA metabolic process (GO:0006399)2.58710826
88proton transport (GO:0015992)2.58198165
89organelle disassembly (GO:1903008)2.55342785
90tRNA processing (GO:0008033)2.54927260
91hydrogen transport (GO:0006818)2.54567241
92establishment of skin barrier (GO:0061436)2.53766672
93eye photoreceptor cell development (GO:0042462)2.53086890
94ribonucleoprotein complex disassembly (GO:0032988)2.51859709
95positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.50063326
96cerebral cortex radially oriented cell migration (GO:0021799)2.49649741
97retinal cone cell development (GO:0046549)2.49641554
98chaperone-mediated protein transport (GO:0072321)2.48310975
99phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.46873201
100regulation of chronic inflammatory response (GO:0002676)2.45976329

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.96250942
2VDR_22108803_ChIP-Seq_LS180_Human4.38931303
3IGF1R_20145208_ChIP-Seq_DFB_Human3.73310221
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.42010202
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.26893437
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.14969575
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.95574059
8ZNF274_21170338_ChIP-Seq_K562_Hela2.64118841
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.63444512
10GBX2_23144817_ChIP-Seq_PC3_Human2.34835056
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.32337426
12PCGF2_27294783_Chip-Seq_NPCs_Mouse2.08809260
13EWS_26573619_Chip-Seq_HEK293_Human2.06530834
14ETS1_20019798_ChIP-Seq_JURKAT_Human1.97310424
15CTBP1_25329375_ChIP-Seq_LNCAP_Human1.90431980
16ZFP57_27257070_Chip-Seq_ESCs_Mouse1.87704575
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.87659325
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.80432092
19IRF1_19129219_ChIP-ChIP_H3396_Human1.80019199
20CTBP2_25329375_ChIP-Seq_LNCAP_Human1.78004528
21ELK1_19687146_ChIP-ChIP_HELA_Human1.69998775
22EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.69941374
23PCGF2_27294783_Chip-Seq_ESCs_Mouse1.67163963
24MYC_18940864_ChIP-ChIP_HL60_Human1.65308253
25VDR_23849224_ChIP-Seq_CD4+_Human1.63502348
26PADI4_21655091_ChIP-ChIP_MCF-7_Human1.62031925
27FUS_26573619_Chip-Seq_HEK293_Human1.59035100
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.56775794
29PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.56385444
30P300_19829295_ChIP-Seq_ESCs_Human1.53397904
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51926999
32TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51409236
33POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.51409236
34SUZ12_27294783_Chip-Seq_NPCs_Mouse1.47590916
35NOTCH1_21737748_ChIP-Seq_TLL_Human1.46780118
36MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.45625651
37AUTS2_25519132_ChIP-Seq_293T-REX_Human1.45436724
38CBP_20019798_ChIP-Seq_JUKART_Human1.42184545
39IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.42184545
40ER_23166858_ChIP-Seq_MCF-7_Human1.41949135
41KLF5_20875108_ChIP-Seq_MESCs_Mouse1.41075142
42GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.39893524
43TTF2_22483619_ChIP-Seq_HELA_Human1.39296097
44GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.36507386
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.35728593
46FOXP3_21729870_ChIP-Seq_TREG_Human1.27216554
47CREB1_15753290_ChIP-ChIP_HEK293T_Human1.26425720
48REST_21632747_ChIP-Seq_MESCs_Mouse1.26316725
49TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.24022211
50NFE2_27457419_Chip-Seq_LIVER_Mouse1.23853129
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.23654321
52NCOR_22424771_ChIP-Seq_293T_Human1.22167359
53TP53_22573176_ChIP-Seq_HFKS_Human1.22151421
54BCAT_22108803_ChIP-Seq_LS180_Human1.19893275
55UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17975728
56EZH2_27294783_Chip-Seq_NPCs_Mouse1.17684032
57GATA3_21878914_ChIP-Seq_MCF-7_Human1.14203318
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.13480054
59CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.13348405
60CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.12598908
61CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.11532281
62ETV2_25802403_ChIP-Seq_MESCs_Mouse1.11339467
63SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.09668860
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.08433656
65FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.07982810
66CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06201974
67TCF4_22108803_ChIP-Seq_LS180_Human1.05775425
68AR_25329375_ChIP-Seq_VCAP_Human1.05169271
69E2F4_17652178_ChIP-ChIP_JURKAT_Human1.03518348
70SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.03117208
71MYC_19829295_ChIP-Seq_ESCs_Human1.02544273
72RNF2_27304074_Chip-Seq_NSC_Mouse1.00993318
73SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.00720153
74P53_21459846_ChIP-Seq_SAOS-2_Human1.00623402
75ERA_21632823_ChIP-Seq_H3396_Human1.00495792
76NANOG_19829295_ChIP-Seq_ESCs_Human0.99981577
77SOX2_19829295_ChIP-Seq_ESCs_Human0.99981577
78FOXA1_25329375_ChIP-Seq_VCAP_Human0.98408642
79FOXA1_27270436_Chip-Seq_PROSTATE_Human0.98408642
80GABP_19822575_ChIP-Seq_HepG2_Human0.97790395
81PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.96007850
82YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.95130397
83STAT3_18555785_Chip-Seq_ESCs_Mouse0.94954880
84P53_22387025_ChIP-Seq_ESCs_Mouse0.94084308
85PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93350708
86AR_20517297_ChIP-Seq_VCAP_Human0.92840454
87EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.92809779
88SUZ12_18555785_Chip-Seq_ESCs_Mouse0.89807703
89HOXB7_26014856_ChIP-Seq_BT474_Human0.88630552
90TAF15_26573619_Chip-Seq_HEK293_Human0.88094583
91RBPJ_21746931_ChIP-Seq_IB4_Human0.87405355
92CRX_20693478_ChIP-Seq_RETINA_Mouse0.86673335
93CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.86620344
94REST_18959480_ChIP-ChIP_MESCs_Mouse0.86413332
95CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.86368934
96PRDM14_20953172_ChIP-Seq_ESCs_Human0.85638822
97GATA6_21074721_ChIP-Seq_CACO-2_Human0.85384155
98TOP2B_26459242_ChIP-Seq_MCF-7_Human0.85071805
99FOXH1_21741376_ChIP-Seq_ESCs_Human0.84718330
100EGR1_23403033_ChIP-Seq_LIVER_Mouse0.84300554

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.38380881
2MP0008789_abnormal_olfactory_epithelium2.97438442
3MP0006072_abnormal_retinal_apoptosis2.95803484
4MP0008877_abnormal_DNA_methylation2.95089905
5MP0000566_synostosis2.84317245
6MP0005394_taste/olfaction_phenotype2.84216240
7MP0005499_abnormal_olfactory_system2.84216240
8MP0005377_hearing/vestibular/ear_phenot2.75693020
9MP0003878_abnormal_ear_physiology2.75693020
10MP0005645_abnormal_hypothalamus_physiol2.55526275
11MP0001348_abnormal_lacrimal_gland2.42029297
12MP0003183_abnormal_peptide_metabolism2.12051599
13MP0002234_abnormal_pharynx_morphology2.09017240
14MP0002163_abnormal_gland_morphology2.04522889
15MP0001984_abnormal_olfaction2.03531471
16MP0001529_abnormal_vocalization1.98680091
17MP0003787_abnormal_imprinting1.97728298
18MP0003890_abnormal_embryonic-extraembry1.96932203
19MP0003122_maternal_imprinting1.92507311
20MP0000778_abnormal_nervous_system1.84857255
21MP0005551_abnormal_eye_electrophysiolog1.77212089
22MP0002796_impaired_skin_barrier1.77150706
23MP0001968_abnormal_touch/_nociception1.73559478
24MP0002736_abnormal_nociception_after1.71032649
25MP0004142_abnormal_muscle_tone1.70286248
26MP0005253_abnormal_eye_physiology1.70147187
27MP0002272_abnormal_nervous_system1.67004239
28MP0009046_muscle_twitch1.64090600
29MP0001919_abnormal_reproductive_system1.59201794
30MP0000579_abnormal_nail_morphology1.58815596
31MP0002653_abnormal_ependyma_morphology1.56868198
32MP0001293_anophthalmia1.51204248
33MP0008995_early_reproductive_senescence1.50781899
34MP0008872_abnormal_physiological_respon1.49625695
35MP0004885_abnormal_endolymph1.47971127
36MP0003880_abnormal_central_pattern1.43584138
37MP0001501_abnormal_sleep_pattern1.39046146
38MP0004133_heterotaxia1.35341173
39MP0001905_abnormal_dopamine_level1.34841074
40MP0001485_abnormal_pinna_reflex1.34487911
41MP0002102_abnormal_ear_morphology1.31613335
42MP0003567_abnormal_fetal_cardiomyocyte1.30536229
43MP0006276_abnormal_autonomic_nervous1.28602973
44MP0001440_abnormal_grooming_behavior1.28351257
45MP0001299_abnormal_eye_distance/1.26417659
46MP0002733_abnormal_thermal_nociception1.25741686
47MP0003121_genomic_imprinting1.25294185
48MP0000631_abnormal_neuroendocrine_gland1.24012275
49MP0005084_abnormal_gallbladder_morpholo1.23441917
50MP0001486_abnormal_startle_reflex1.23145093
51MP0008057_abnormal_DNA_replication1.22095677
52MP0004145_abnormal_muscle_electrophysio1.20771131
53MP0002572_abnormal_emotion/affect_behav1.20666049
54MP0001970_abnormal_pain_threshold1.19152111
55MP0004043_abnormal_pH_regulation1.18382959
56MP0005389_reproductive_system_phenotype1.18219908
57MP0005379_endocrine/exocrine_gland_phen1.17827918
58MP0002067_abnormal_sensory_capabilities1.17118526
59MP0000955_abnormal_spinal_cord1.16133430
60MP0003635_abnormal_synaptic_transmissio1.13326975
61MP0002638_abnormal_pupillary_reflex1.12962218
62MP0002938_white_spotting1.11661520
63MP0002184_abnormal_innervation1.10843978
64MP0008775_abnormal_heart_ventricle1.09808956
65MP0009745_abnormal_behavioral_response1.09751719
66MP0005647_abnormal_sex_gland1.08379569
67MP0002063_abnormal_learning/memory/cond1.07356383
68MP0002098_abnormal_vibrissa_morphology1.04151417
69MP0002735_abnormal_chemical_nociception1.03232196
70MP0005195_abnormal_posterior_eye1.03222869
71MP0002557_abnormal_social/conspecific_i1.03133389
72MP0000049_abnormal_middle_ear1.03032606
73MP0003718_maternal_effect0.98556406
74MP0002160_abnormal_reproductive_system0.98312162
75MP0006035_abnormal_mitochondrial_morpho0.97714239
76MP0005410_abnormal_fertilization0.95961687
77MP0005391_vision/eye_phenotype0.94336137
78MP0001119_abnormal_female_reproductive0.92598384
79MP0002210_abnormal_sex_determination0.92007864
80MP0000427_abnormal_hair_cycle0.86419663
81MP0003646_muscle_fatigue0.85131984
82MP0002876_abnormal_thyroid_physiology0.84166681
83MP0003186_abnormal_redox_activity0.83845673
84MP0002752_abnormal_somatic_nervous0.80879228
85MP0005501_abnormal_skin_physiology0.79203012
86MP0002233_abnormal_nose_morphology0.77964292
87MP0000026_abnormal_inner_ear0.77198938
88MP0009053_abnormal_anal_canal0.76853396
89MP0008875_abnormal_xenobiotic_pharmacok0.75335259
90MP0003698_abnormal_male_reproductive0.74463716
91MP0002882_abnormal_neuron_morphology0.73698581
92MP0005083_abnormal_biliary_tract0.73200352
93MP0000647_abnormal_sebaceous_gland0.72828647
94MP0001986_abnormal_taste_sensitivity0.71610949
95MP0000230_abnormal_systemic_arterial0.71455520
96MP0000372_irregular_coat_pigmentation0.71233559
97MP0009764_decreased_sensitivity_to0.70735004
98MP0003221_abnormal_cardiomyocyte_apopto0.70272329
99MP0000383_abnormal_hair_follicle0.69901373
100MP0000653_abnormal_sex_gland0.69864069

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.02899251
2Molar tooth sign on MRI (HP:0002419)3.69818515
3Abnormality of midbrain morphology (HP:0002418)3.69818515
4Parakeratosis (HP:0001036)3.60088895
5Nephronophthisis (HP:0000090)3.59769610
6Absent rod-and cone-mediated responses on ERG (HP:0007688)3.49376305
7Acute encephalopathy (HP:0006846)3.42618739
8Abnormal mitochondria in muscle tissue (HP:0008316)3.27762856
9Progressive macrocephaly (HP:0004481)3.27376365
10Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.25562337
11Pancreatic fibrosis (HP:0100732)3.19969976
12Abnormality of the labia minora (HP:0012880)3.06103597
13Congenital ichthyosiform erythroderma (HP:0007431)2.88776150
14Abnormality of nail color (HP:0100643)2.84952364
15Abnormality of the renal medulla (HP:0100957)2.84001263
16Pancreatic cysts (HP:0001737)2.81086051
17Hypomagnesemia (HP:0002917)2.79822501
18Pachygyria (HP:0001302)2.78077997
19Erythroderma (HP:0001019)2.77911645
20Abnormal rod and cone electroretinograms (HP:0008323)2.70248519
21Congenital stationary night blindness (HP:0007642)2.65225801
22Cerebral edema (HP:0002181)2.60323556
23True hermaphroditism (HP:0010459)2.59009080
24Increased CSF lactate (HP:0002490)2.54703814
25Lissencephaly (HP:0001339)2.54325427
26Oral leukoplakia (HP:0002745)2.49791538
27Mitochondrial inheritance (HP:0001427)2.49152187
28Medial flaring of the eyebrow (HP:0010747)2.47093960
29Adrenal hypoplasia (HP:0000835)2.40555660
30Esophageal atresia (HP:0002032)2.40187488
31Prolonged partial thromboplastin time (HP:0003645)2.37492707
32Postaxial foot polydactyly (HP:0001830)2.36078242
33Arthropathy (HP:0003040)2.35927540
34Shawl scrotum (HP:0000049)2.34274080
35Rib fusion (HP:0000902)2.33134203
36Optic disc pallor (HP:0000543)2.32603463
37Abnormal pancreas size (HP:0012094)2.27636677
38Abnormality of magnesium homeostasis (HP:0004921)2.26317329
39Septo-optic dysplasia (HP:0100842)2.25472703
40Renal salt wasting (HP:0000127)2.25099413
41Large eyes (HP:0001090)2.23337951
42Pigmentary retinal degeneration (HP:0001146)2.22690244
43Aplasia/hypoplasia of the uterus (HP:0008684)2.22387062
44Abolished electroretinogram (ERG) (HP:0000550)2.21549837
45Type II lissencephaly (HP:0007260)2.16209324
46Anophthalmia (HP:0000528)2.14605679
47Aplasia/Hypoplasia of the spleen (HP:0010451)2.13128006
48Abnormality of alanine metabolism (HP:0010916)2.10932574
49Hyperalaninemia (HP:0003348)2.10932574
50Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.10932574
51Oligodactyly (hands) (HP:0001180)2.09969751
523-Methylglutaconic aciduria (HP:0003535)2.07217226
53Congenital hepatic fibrosis (HP:0002612)2.06875792
54Mesomelia (HP:0003027)2.06312323
55Degeneration of anterior horn cells (HP:0002398)2.03871401
56Abnormality of the anterior horn cell (HP:0006802)2.03871401
57Decreased central vision (HP:0007663)2.01294532
58Oligodactyly (HP:0012165)2.01220552
59Hypohidrosis (HP:0000966)1.99603843
60Horseshoe kidney (HP:0000085)1.98504076
61Median cleft lip (HP:0000161)1.97053548
62Narrow forehead (HP:0000341)1.96810639
63Decreased electroretinogram (ERG) amplitude (HP:0000654)1.96190868
64Type I transferrin isoform profile (HP:0003642)1.94241356
65Small hand (HP:0200055)1.93802323
66Pendular nystagmus (HP:0012043)1.91752607
67Drooling (HP:0002307)1.91016497
68Spinal muscular atrophy (HP:0007269)1.90683128
69Poor head control (HP:0002421)1.87424990
70Polyuria (HP:0000103)1.86442597
71Elevated erythrocyte sedimentation rate (HP:0003565)1.83544788
72Limb dystonia (HP:0002451)1.83441101
73Abnormality of the renal cortex (HP:0011035)1.81762495
74Gait imbalance (HP:0002141)1.81660841
75Type 2 muscle fiber atrophy (HP:0003554)1.81087391
76Dynein arm defect of respiratory motile cilia (HP:0012255)1.79298778
77Absent/shortened dynein arms (HP:0200106)1.79298778
78Abnormal drinking behavior (HP:0030082)1.78670840
79Polydipsia (HP:0001959)1.78670840
80Limb hypertonia (HP:0002509)1.78497651
81Tubular atrophy (HP:0000092)1.78173465
82Fragile nails (HP:0001808)1.77751780
83Hypoplasia of the brainstem (HP:0002365)1.77393409
84Aplasia/Hypoplasia of the brainstem (HP:0007362)1.77393409
85Hyperventilation (HP:0002883)1.77371052
86Amniotic constriction ring (HP:0009775)1.75390900
87Abnormality of placental membranes (HP:0011409)1.75390900
88Ectopic kidney (HP:0000086)1.74854943
89Abnormality of the corticospinal tract (HP:0002492)1.73525104
90Preaxial hand polydactyly (HP:0001177)1.73018674
91Leukodystrophy (HP:0002415)1.71226702
92Large for gestational age (HP:0001520)1.71005460
93Abnormal sex determination (HP:0012244)1.70748052
94Sex reversal (HP:0012245)1.70748052
95Hypoplasia of the uterus (HP:0000013)1.70468460
96Supernumerary spleens (HP:0009799)1.70457050
97Furrowed tongue (HP:0000221)1.70361088
98Cystic liver disease (HP:0006706)1.70216753
99Degeneration of the lateral corticospinal tracts (HP:0002314)1.70112699
100Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.70112699

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TSSK63.76529694
2MAPKAPK53.06740692
3WNK33.00275961
4WNK42.87216075
5CASK2.83111067
6AKT32.70088981
7EIF2AK32.62041784
8ADRBK22.44965327
9DYRK22.19597198
10CDK192.13926785
11TLK12.09015203
12PLK42.06024455
13FER2.04687060
14PINK12.02548168
15CAMKK22.02249719
16FES1.96115248
17EPHB21.91496661
18EIF2AK11.88179116
19MAP4K21.86387740
20PNCK1.76386841
21ZAK1.71274559
22BCR1.66329732
23MST41.63804034
24PLK21.60592045
25MKNK21.53462846
26MARK11.43579788
27EPHA31.38876011
28NUAK11.38602687
29TXK1.36245767
30MAPK131.32674301
31TRIM281.31984733
32EIF2AK21.31601321
33SRPK11.22872095
34STK391.21010294
35SGK21.20274040
36MAP3K41.10736805
37GRK11.10599178
38TAF11.09950033
39SGK2231.07307259
40SGK4941.07307259
41PRKD31.05597605
42VRK21.04755003
43WNK10.97936484
44FRK0.97888818
45BCKDK0.97829894
46PLK30.96851273
47DYRK30.89257321
48VRK10.88458351
49TYRO30.85521339
50PRKCE0.85455662
51RPS6KA50.85353663
52PKN10.82961810
53MKNK10.81492618
54PAK30.81185233
55MAP2K70.81130141
56MAP3K110.79376133
57IRAK40.78356198
58CLK10.76100183
59BMPR1B0.70819700
60CSNK1G10.69162604
61MAP2K60.67855273
62KIT0.66307873
63CAMK10.65962173
64MINK10.64682322
65ALK0.64447447
66CSNK1G20.64220948
67TIE10.60883668
68SGK30.59507930
69EPHA40.58561872
70TGFBR10.57972783
71PDK20.57451080
72PRKCG0.56534933
73NLK0.55608387
74ADRBK10.54884373
75BRAF0.53868731
76WEE10.51742907
77TAOK30.51318770
78CSNK1A10.51002909
79MAP2K40.50350353
80ATR0.48411051
81CSNK1G30.46905719
82OXSR10.46846399
83MAPK120.46554160
84FGFR40.46201900
85DMPK0.45047056
86CSNK1E0.44938112
87SGK10.42478571
88PHKG20.39680658
89PHKG10.39680658
90BUB10.39126118
91NEK10.37020816
92IRAK10.36771232
93CAMK2A0.36677441
94INSRR0.35772430
95CSNK2A20.34993149
96AKT20.32522571
97PRKACA0.31879996
98PAK60.31192903
99CSNK1A1L0.30889122
100DYRK1B0.30077447

Predicted pathways (KEGG)

RankGene SetZ-score
1alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.19825873
2Proteasome_Homo sapiens_hsa030503.08656932
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.05112710
4Linoleic acid metabolism_Homo sapiens_hsa005912.96446318
5Oxidative phosphorylation_Homo sapiens_hsa001902.91591392
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.79943481
7Parkinsons disease_Homo sapiens_hsa050122.64748985
8Mismatch repair_Homo sapiens_hsa034302.63346778
9Ribosome_Homo sapiens_hsa030102.29407800
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.13124659
11Homologous recombination_Homo sapiens_hsa034402.03434068
12One carbon pool by folate_Homo sapiens_hsa006702.01899233
13Ether lipid metabolism_Homo sapiens_hsa005651.94891124
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.93523231
15RNA polymerase_Homo sapiens_hsa030201.89998844
16Basal transcription factors_Homo sapiens_hsa030221.89028033
17Huntingtons disease_Homo sapiens_hsa050161.80630059
18Nicotine addiction_Homo sapiens_hsa050331.80425813
19Phototransduction_Homo sapiens_hsa047441.76619280
20Spliceosome_Homo sapiens_hsa030401.71272474
21DNA replication_Homo sapiens_hsa030301.69397752
22RNA degradation_Homo sapiens_hsa030181.63496502
23Steroid biosynthesis_Homo sapiens_hsa001001.60238227
24RNA transport_Homo sapiens_hsa030131.54021736
25Alzheimers disease_Homo sapiens_hsa050101.44438216
26Butanoate metabolism_Homo sapiens_hsa006501.41907815
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.36913728
28Propanoate metabolism_Homo sapiens_hsa006401.35711452
29Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.34397165
30Cardiac muscle contraction_Homo sapiens_hsa042601.34362555
31Nucleotide excision repair_Homo sapiens_hsa034201.31341211
32Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.30908176
33Antigen processing and presentation_Homo sapiens_hsa046121.28205814
34Fat digestion and absorption_Homo sapiens_hsa049751.22627572
35Arachidonic acid metabolism_Homo sapiens_hsa005901.21863867
36Collecting duct acid secretion_Homo sapiens_hsa049661.18823035
37Non-homologous end-joining_Homo sapiens_hsa034501.18631033
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12049633
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.11133678
40Protein export_Homo sapiens_hsa030601.09159178
41GABAergic synapse_Homo sapiens_hsa047271.06839719
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.05804023
43Fanconi anemia pathway_Homo sapiens_hsa034601.03081800
44Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.97988020
45Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.97623726
46Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.97291470
47Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.94562498
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.91228486
49Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.88761040
50Pyrimidine metabolism_Homo sapiens_hsa002400.81408947
51Asthma_Homo sapiens_hsa053100.81119436
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.76860192
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.75076649
54Morphine addiction_Homo sapiens_hsa050320.74866823
55Nitrogen metabolism_Homo sapiens_hsa009100.73412236
56Tryptophan metabolism_Homo sapiens_hsa003800.73148468
57Chemical carcinogenesis_Homo sapiens_hsa052040.71420078
58Alcoholism_Homo sapiens_hsa050340.69891741
59Purine metabolism_Homo sapiens_hsa002300.67920798
60Serotonergic synapse_Homo sapiens_hsa047260.66571058
61Cyanoamino acid metabolism_Homo sapiens_hsa004600.66048891
62Taste transduction_Homo sapiens_hsa047420.66021720
63Systemic lupus erythematosus_Homo sapiens_hsa053220.65717327
64NOD-like receptor signaling pathway_Homo sapiens_hsa046210.64073250
65Glycerolipid metabolism_Homo sapiens_hsa005610.63817428
66Hedgehog signaling pathway_Homo sapiens_hsa043400.63000819
67Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.61859388
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61454834
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.60791830
70Glutamatergic synapse_Homo sapiens_hsa047240.60060257
71Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.58696811
72Synaptic vesicle cycle_Homo sapiens_hsa047210.54037050
73Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.53319624
74Metabolic pathways_Homo sapiens_hsa011000.51743258
75Fatty acid metabolism_Homo sapiens_hsa012120.50175627
76Circadian entrainment_Homo sapiens_hsa047130.49134738
77Fatty acid degradation_Homo sapiens_hsa000710.47926837
78Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.47603721
79Peroxisome_Homo sapiens_hsa041460.47571814
80Fatty acid biosynthesis_Homo sapiens_hsa000610.46274495
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.45817540
82Long-term depression_Homo sapiens_hsa047300.45577513
83ABC transporters_Homo sapiens_hsa020100.45416183
84Type I diabetes mellitus_Homo sapiens_hsa049400.42592228
85Fatty acid elongation_Homo sapiens_hsa000620.41136659
86Maturity onset diabetes of the young_Homo sapiens_hsa049500.40776968
87Ovarian steroidogenesis_Homo sapiens_hsa049130.40719004
88Retinol metabolism_Homo sapiens_hsa008300.40002287
89Primary immunodeficiency_Homo sapiens_hsa053400.39862604
90Sulfur relay system_Homo sapiens_hsa041220.39345985
91Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36420039
92Dopaminergic synapse_Homo sapiens_hsa047280.36382415
93Drug metabolism - other enzymes_Homo sapiens_hsa009830.34882214
94Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.34535766
95Olfactory transduction_Homo sapiens_hsa047400.34160571
96Salivary secretion_Homo sapiens_hsa049700.33756956
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.33624077
98Caffeine metabolism_Homo sapiens_hsa002320.32309542
99Circadian rhythm_Homo sapiens_hsa047100.30189802
100p53 signaling pathway_Homo sapiens_hsa041150.29731966

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