ST13P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.29969945
2behavioral response to nicotine (GO:0035095)4.95165336
3cytidine deamination (GO:0009972)4.26542028
4cytidine metabolic process (GO:0046087)4.26542028
5cytidine catabolic process (GO:0006216)4.26542028
6L-methionine salvage (GO:0071267)4.04958927
7L-methionine biosynthetic process (GO:0071265)4.04958927
8amino acid salvage (GO:0043102)4.04958927
9L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.03355346
10mitochondrial respiratory chain complex I assembly (GO:0032981)4.02235488
11NADH dehydrogenase complex assembly (GO:0010257)4.02235488
12mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.02235488
13preassembly of GPI anchor in ER membrane (GO:0016254)4.00691736
14fucose catabolic process (GO:0019317)3.80200554
15L-fucose metabolic process (GO:0042354)3.80200554
16L-fucose catabolic process (GO:0042355)3.80200554
17pyrimidine ribonucleoside catabolic process (GO:0046133)3.76849783
18detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.75111446
19protein complex biogenesis (GO:0070271)3.74243639
20protein polyglutamylation (GO:0018095)3.67801400
21ubiquinone biosynthetic process (GO:0006744)3.65464442
22mannosylation (GO:0097502)3.59228504
23protein deneddylation (GO:0000338)3.56857539
24piRNA metabolic process (GO:0034587)3.52326718
25pseudouridine synthesis (GO:0001522)3.49932262
26proteasome assembly (GO:0043248)3.46745805
27mitochondrial respiratory chain complex assembly (GO:0033108)3.42165728
28synaptic transmission, cholinergic (GO:0007271)3.40653551
29protein neddylation (GO:0045116)3.39505033
30ubiquinone metabolic process (GO:0006743)3.34112722
31metallo-sulfur cluster assembly (GO:0031163)3.32647416
32iron-sulfur cluster assembly (GO:0016226)3.32647416
33regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.31942056
34positive regulation of defense response to virus by host (GO:0002230)3.31636617
35mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.24364406
36nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.14187481
37base-excision repair, AP site formation (GO:0006285)3.13370354
38chaperone mediated protein folding requiring cofactor (GO:0051085)3.12596167
39rRNA catabolic process (GO:0016075)3.12322160
40negative regulation of reactive oxygen species metabolic process (GO:2000378)3.06862922
41cullin deneddylation (GO:0010388)3.06505327
42aldehyde catabolic process (GO:0046185)3.04816990
43multicellular organism reproduction (GO:0032504)3.04707830
44positive regulation of T-helper 1 type immune response (GO:0002827)2.97683602
45exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.97093289
46regulation of cellular amino acid metabolic process (GO:0006521)2.93685651
47negative regulation by host of viral transcription (GO:0043922)2.92470396
48S-adenosylmethionine metabolic process (GO:0046500)2.91458422
49maturation of 5.8S rRNA (GO:0000460)2.91019874
50DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.90946612
51quinone biosynthetic process (GO:1901663)2.88289828
52retinal cone cell development (GO:0046549)2.86810589
53water-soluble vitamin biosynthetic process (GO:0042364)2.86676200
54RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.85279876
55tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.85279876
56signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.83114772
57signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.83114772
58signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.83114772
59regulation of mitochondrial translation (GO:0070129)2.79960135
60peptidyl-histidine modification (GO:0018202)2.78293401
61intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.78058262
62signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.78058262
63meiotic cell cycle (GO:0051321)2.77394187
64positive regulation of protein homodimerization activity (GO:0090073)2.75111066
65signal transduction involved in cell cycle checkpoint (GO:0072395)2.74893696
66signal transduction involved in DNA integrity checkpoint (GO:0072401)2.71837508
67signal transduction involved in DNA damage checkpoint (GO:0072422)2.71837508
68replicative senescence (GO:0090399)2.70861181
69C-terminal protein amino acid modification (GO:0018410)2.70743042
70drug catabolic process (GO:0042737)2.70541193
71adaptation of signaling pathway (GO:0023058)2.68582737
72rRNA modification (GO:0000154)2.68073579
73male meiosis I (GO:0007141)2.67630608
74methionine biosynthetic process (GO:0009086)2.67512361
75auditory receptor cell stereocilium organization (GO:0060088)2.67057584
76C-terminal protein lipidation (GO:0006501)2.66458773
77phosphatidylserine acyl-chain remodeling (GO:0036150)2.66018251
78detection of mechanical stimulus involved in sensory perception (GO:0050974)2.65616693
79negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.63732194
80GPI anchor metabolic process (GO:0006505)2.63717829
81pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.61464097
82DNA methylation involved in gamete generation (GO:0043046)2.61099006
83protein import into peroxisome matrix (GO:0016558)2.58888325
84response to pheromone (GO:0019236)2.56537102
85methionine metabolic process (GO:0006555)2.56495441
86positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.55652243
87GPI anchor biosynthetic process (GO:0006506)2.54673472
88cellular response to interleukin-15 (GO:0071350)2.54432452
89rRNA methylation (GO:0031167)2.54387549
90platelet dense granule organization (GO:0060155)2.54358171
91regulation of immunoglobulin secretion (GO:0051023)2.51438026
92electron transport chain (GO:0022900)2.51107693
93tRNA processing (GO:0008033)2.49825223
94respiratory chain complex IV assembly (GO:0008535)2.49397472
95phosphatidylinositol acyl-chain remodeling (GO:0036149)2.49247074
96seminiferous tubule development (GO:0072520)2.47980088
97cellular response to nicotine (GO:0071316)2.47785570
98ribosome biogenesis (GO:0042254)2.47681741
99pattern specification involved in kidney development (GO:0061004)2.45191327
100respiratory electron transport chain (GO:0022904)2.44284316

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.50694799
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.53092659
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.36948420
4BP1_19119308_ChIP-ChIP_Hs578T_Human3.06980227
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.01214650
6VDR_22108803_ChIP-Seq_LS180_Human3.00312330
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.97606739
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.95333642
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.93990560
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.89069590
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.71211401
12ZNF274_21170338_ChIP-Seq_K562_Hela2.67888174
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.36275916
14TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.28528115
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.25620034
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.16016595
17PCGF2_27294783_Chip-Seq_ESCs_Mouse2.09742081
18VDR_23849224_ChIP-Seq_CD4+_Human2.04750230
19EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.98489986
20PCGF2_27294783_Chip-Seq_NPCs_Mouse1.92511034
21MYC_18940864_ChIP-ChIP_HL60_Human1.86175994
22SRF_21415370_ChIP-Seq_HL-1_Mouse1.85735468
23EGR1_23403033_ChIP-Seq_LIVER_Mouse1.83021145
24GBX2_23144817_ChIP-Seq_PC3_Human1.80296710
25TP53_22573176_ChIP-Seq_HFKS_Human1.79360120
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.76868106
27IGF1R_20145208_ChIP-Seq_DFB_Human1.73220182
28CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.71273205
29IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.67857613
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.57136990
31FOXP3_21729870_ChIP-Seq_TREG_Human1.53855374
32ELK1_19687146_ChIP-ChIP_HELA_Human1.53198862
33NOTCH1_21737748_ChIP-Seq_TLL_Human1.46807132
34CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.41632981
35NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.41027032
36CBP_20019798_ChIP-Seq_JUKART_Human1.40093995
37IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40093995
38PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.38160169
39FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.37238365
40GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.36373618
41TAF2_19829295_ChIP-Seq_ESCs_Human1.34073395
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.30964603
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.28193279
44IRF1_19129219_ChIP-ChIP_H3396_Human1.28102782
45GABP_19822575_ChIP-Seq_HepG2_Human1.27905207
46AUTS2_25519132_ChIP-Seq_293T-REX_Human1.27055376
47AR_20517297_ChIP-Seq_VCAP_Human1.26155687
48NFE2_27457419_Chip-Seq_LIVER_Mouse1.26103686
49GATA3_21878914_ChIP-Seq_MCF-7_Human1.25348458
50EWS_26573619_Chip-Seq_HEK293_Human1.25055238
51SUZ12_27294783_Chip-Seq_NPCs_Mouse1.24544749
52ER_23166858_ChIP-Seq_MCF-7_Human1.22911894
53CTBP1_25329375_ChIP-Seq_LNCAP_Human1.21477012
54FUS_26573619_Chip-Seq_HEK293_Human1.18784941
55FOXA1_27270436_Chip-Seq_PROSTATE_Human1.17567426
56FOXA1_25329375_ChIP-Seq_VCAP_Human1.17567426
57NANOG_19829295_ChIP-Seq_ESCs_Human1.13947506
58SOX2_19829295_ChIP-Seq_ESCs_Human1.13947506
59CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.12458003
60MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10338963
61NANOG_20526341_ChIP-Seq_ESCs_Human1.09683163
62NCOR_22424771_ChIP-Seq_293T_Human1.09190433
63HOXB7_26014856_ChIP-Seq_BT474_Human1.08337395
64MYC_19829295_ChIP-Seq_ESCs_Human1.07808998
65P53_21459846_ChIP-Seq_SAOS-2_Human1.07370012
66SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.05778913
67FOXH1_21741376_ChIP-Seq_EPCs_Human1.05629583
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.05275274
69CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.04361974
70FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.03784586
71TAF15_26573619_Chip-Seq_HEK293_Human1.02874715
72MYC_18358816_ChIP-ChIP_MESCs_Mouse1.02864866
73ETV2_25802403_ChIP-Seq_MESCs_Mouse1.02662231
74CRX_20693478_ChIP-Seq_RETINA_Mouse1.02524758
75EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.01353625
76CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00691511
77RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00513617
78TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.00325203
79GATA3_26560356_Chip-Seq_TH1_Human1.00184687
80LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00116731
81ERA_21632823_ChIP-Seq_H3396_Human0.99212513
82RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.98602284
83EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.98327431
84STAT1_20625510_ChIP-Seq_HELA_Human0.97842870
85FOXA1_21572438_ChIP-Seq_LNCaP_Human0.96978673
86MYC_18555785_ChIP-Seq_MESCs_Mouse0.96207785
87FOXH1_21741376_ChIP-Seq_ESCs_Human0.94909890
88PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93773145
89POU3F2_20337985_ChIP-ChIP_501MEL_Human0.93670167
90PADI4_21655091_ChIP-ChIP_MCF-7_Human0.93617275
91PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93349925
92NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.92649555
93FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.91978240
94OCT4_20526341_ChIP-Seq_ESCs_Human0.89781945
95IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.89422750
96GATA3_26560356_Chip-Seq_TH2_Human0.88841682
97BCAT_22108803_ChIP-Seq_LS180_Human0.88808458
98CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88156576
99PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.88013431
100BCL6_27268052_Chip-Seq_Bcells_Human0.87018670

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000372_irregular_coat_pigmentation4.43996832
2MP0002138_abnormal_hepatobiliary_system2.94883578
3MP0006292_abnormal_olfactory_placode2.93815468
4MP0008789_abnormal_olfactory_epithelium2.86767972
5MP0008877_abnormal_DNA_methylation2.85271584
6MP0003718_maternal_effect2.68694012
7MP0006276_abnormal_autonomic_nervous2.65417695
8MP0003787_abnormal_imprinting2.63929850
9MP0001529_abnormal_vocalization2.52482633
10MP0005394_taste/olfaction_phenotype2.38768917
11MP0005499_abnormal_olfactory_system2.38768917
12MP0003646_muscle_fatigue2.32697521
13MP0002234_abnormal_pharynx_morphology2.26937797
14MP0002102_abnormal_ear_morphology2.26834052
15MP0005551_abnormal_eye_electrophysiolog2.16537014
16MP0001986_abnormal_taste_sensitivity2.12329555
17MP0002638_abnormal_pupillary_reflex2.03170641
18MP0006072_abnormal_retinal_apoptosis1.97935134
19MP0005671_abnormal_response_to1.96817772
20MP0005645_abnormal_hypothalamus_physiol1.95506126
21MP0005360_urolithiasis1.92380526
22MP0001984_abnormal_olfaction1.88416345
23MP0002163_abnormal_gland_morphology1.85366536
24MP0008875_abnormal_xenobiotic_pharmacok1.71837336
25MP0001905_abnormal_dopamine_level1.71556313
26MP0002876_abnormal_thyroid_physiology1.70158976
27MP0004142_abnormal_muscle_tone1.66184375
28MP0005075_abnormal_melanosome_morpholog1.66027551
29MP0008775_abnormal_heart_ventricle1.58679338
30MP0000569_abnormal_digit_pigmentation1.58124789
31MP0008872_abnormal_physiological_respon1.52395044
32MP0004145_abnormal_muscle_electrophysio1.49968172
33MP0005377_hearing/vestibular/ear_phenot1.46287011
34MP0003878_abnormal_ear_physiology1.46287011
35MP0006036_abnormal_mitochondrial_physio1.42083206
36MP0002733_abnormal_thermal_nociception1.41915876
37MP0003879_abnormal_hair_cell1.41609224
38MP0000685_abnormal_immune_system1.41184304
39MP0002139_abnormal_hepatobiliary_system1.38382563
40MP0005379_endocrine/exocrine_gland_phen1.35312665
41MP0003011_delayed_dark_adaptation1.33301014
42MP0002653_abnormal_ependyma_morphology1.32503846
43MP0001835_abnormal_antigen_presentation1.28851216
44MP0004147_increased_porphyrin_level1.28745351
45MP0009785_altered_susceptibility_to1.26183810
46MP0005389_reproductive_system_phenotype1.20282269
47MP0001501_abnormal_sleep_pattern1.19106920
48MP0004924_abnormal_behavior1.16548240
49MP0005386_behavior/neurological_phenoty1.16548240
50MP0005253_abnormal_eye_physiology1.13856553
51MP0003195_calcinosis1.13785239
52MP0005410_abnormal_fertilization1.13168758
53MP0003890_abnormal_embryonic-extraembry1.11763712
54MP0009745_abnormal_behavioral_response1.10665960
55MP0002160_abnormal_reproductive_system1.10508662
56MP0001968_abnormal_touch/_nociception1.09665730
57MP0002272_abnormal_nervous_system1.09285196
58MP0004084_abnormal_cardiac_muscle1.08236732
59MP0005332_abnormal_amino_acid1.07469945
60MP0003806_abnormal_nucleotide_metabolis1.02645285
61MP0001790_abnormal_immune_system0.96889523
62MP0005387_immune_system_phenotype0.96889523
63MP0009046_muscle_twitch0.96093425
64MP0001502_abnormal_circadian_rhythm0.94617486
65MP0005395_other_phenotype0.92504622
66MP0001970_abnormal_pain_threshold0.90212086
67MP0003693_abnormal_embryo_hatching0.90158286
68MP0004043_abnormal_pH_regulation0.90132173
69MP0005423_abnormal_somatic_nervous0.89197298
70MP0009764_decreased_sensitivity_to0.88634425
71MP0004036_abnormal_muscle_relaxation0.85010870
72MP0002006_tumorigenesis0.84927122
73MP0010386_abnormal_urinary_bladder0.84744266
74MP0003786_premature_aging0.83802445
75MP0001881_abnormal_mammary_gland0.83032531
76MP0000427_abnormal_hair_cycle0.81050542
77MP0000613_abnormal_salivary_gland0.80188479
78MP0002067_abnormal_sensory_capabilities0.79968738
79MP0008995_early_reproductive_senescence0.79508689
80MP0001919_abnormal_reproductive_system0.78904800
81MP0003121_genomic_imprinting0.78802232
82MP0001293_anophthalmia0.78744364
83MP0002148_abnormal_hypersensitivity_rea0.77890943
84MP0003329_amyloid_beta_deposits0.77754739
85MP0003137_abnormal_impulse_conducting0.77007019
86MP0002572_abnormal_emotion/affect_behav0.76353843
87MP0001485_abnormal_pinna_reflex0.76046582
88MP0002751_abnormal_autonomic_nervous0.75942751
89MP0001764_abnormal_homeostasis0.75725596
90MP0005195_abnormal_posterior_eye0.75315361
91MP0001929_abnormal_gametogenesis0.74450931
92MP0005174_abnormal_tail_pigmentation0.74405970
93MP0002090_abnormal_vision0.73961894
94MP0002166_altered_tumor_susceptibility0.73125315
95MP0005365_abnormal_bile_salt0.72740908
96MP0002277_abnormal_respiratory_mucosa0.70872336
97MP0002752_abnormal_somatic_nervous0.70129143
98MP0002332_abnormal_exercise_endurance0.69361538
99MP0002735_abnormal_chemical_nociception0.68651508
100MP0002229_neurodegeneration0.66999931

Predicted human phenotypes

RankGene SetZ-score
13-Methylglutaconic aciduria (HP:0003535)4.24462617
2Abnormality of midbrain morphology (HP:0002418)4.18300488
3Molar tooth sign on MRI (HP:0002419)4.18300488
4Acute necrotizing encephalopathy (HP:0006965)4.03833350
5Stomatitis (HP:0010280)3.95647586
6Abnormal mitochondria in muscle tissue (HP:0008316)3.78277717
7Congenital stationary night blindness (HP:0007642)3.67753407
8Acute encephalopathy (HP:0006846)3.48274932
9Increased CSF lactate (HP:0002490)3.44093359
10Mitochondrial inheritance (HP:0001427)3.38031602
11Type II lissencephaly (HP:0007260)3.35601541
12Progressive macrocephaly (HP:0004481)3.33375473
13Pancreatic cysts (HP:0001737)3.05194392
14Decreased electroretinogram (ERG) amplitude (HP:0000654)2.99497600
15Abnormality of the labia minora (HP:0012880)2.92572865
16Hepatocellular necrosis (HP:0001404)2.89988874
17True hermaphroditism (HP:0010459)2.88945304
18IgG deficiency (HP:0004315)2.85088428
19Increased serum lactate (HP:0002151)2.78460907
20Abnormal rod and cone electroretinograms (HP:0008323)2.77614559
21Cerebral edema (HP:0002181)2.76999301
22Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.67347489
23Abnormality of alanine metabolism (HP:0010916)2.67347489
24Hyperalaninemia (HP:0003348)2.67347489
25Hepatic necrosis (HP:0002605)2.58994368
26Absent rod-and cone-mediated responses on ERG (HP:0007688)2.57903532
27Aplasia/Hypoplasia of the tongue (HP:0010295)2.52959410
28Increased IgM level (HP:0003496)2.51421736
29Type I transferrin isoform profile (HP:0003642)2.46337572
30Generalized aminoaciduria (HP:0002909)2.43688193
31Hypophosphatemic rickets (HP:0004912)2.43092717
32Lactic acidosis (HP:0003128)2.39308385
33Pancreatic fibrosis (HP:0100732)2.33867080
34Abolished electroretinogram (ERG) (HP:0000550)2.33727986
35Abnormality of the pons (HP:0007361)2.33256411
36Methylmalonic aciduria (HP:0012120)2.32022316
37Congenital, generalized hypertrichosis (HP:0004540)2.30684171
38Delayed CNS myelination (HP:0002188)2.28164822
39Broad alveolar ridges (HP:0000187)2.27845551
40Fair hair (HP:0002286)2.27819296
41Medial flaring of the eyebrow (HP:0010747)2.25974336
42Increased intramyocellular lipid droplets (HP:0012240)2.23507957
43Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.21258524
44Decreased activity of mitochondrial respiratory chain (HP:0008972)2.21258524
45Progressive inability to walk (HP:0002505)2.18910616
46Septo-optic dysplasia (HP:0100842)2.17733486
47Nephronophthisis (HP:0000090)2.17673616
48Methylmalonic acidemia (HP:0002912)2.16522764
49Renal cortical cysts (HP:0000803)2.15668396
50Optic disc pallor (HP:0000543)2.15270130
51Failure to thrive in infancy (HP:0001531)2.13025712
52Retinal dysplasia (HP:0007973)2.11828844
53Progressive microcephaly (HP:0000253)2.11128846
54Agitation (HP:0000713)2.10664300
55IgA deficiency (HP:0002720)2.09787836
56Abnormality of the renal cortex (HP:0011035)2.07337064
57Abnormal protein glycosylation (HP:0012346)2.07040638
58Abnormal glycosylation (HP:0012345)2.07040638
59Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.07040638
60Abnormal protein N-linked glycosylation (HP:0012347)2.07040638
61Lethargy (HP:0001254)2.06877368
62Carpal bone hypoplasia (HP:0001498)2.06618017
63Chronic diarrhea (HP:0002028)2.04791388
64Inability to walk (HP:0002540)2.03721460
65Abnormal drinking behavior (HP:0030082)2.01301818
66Polydipsia (HP:0001959)2.01301818
67Cerebellar dysplasia (HP:0007033)1.99856695
68Arthropathy (HP:0003040)1.99168079
69Lissencephaly (HP:0001339)1.97100925
70Pachygyria (HP:0001302)1.94537648
71Chronic hepatic failure (HP:0100626)1.94224150
72Abnormality of dental color (HP:0011073)1.92574390
73Sclerocornea (HP:0000647)1.92012304
74Renal Fanconi syndrome (HP:0001994)1.89286468
75Respiratory failure (HP:0002878)1.88817277
76Exercise intolerance (HP:0003546)1.88163018
77Attenuation of retinal blood vessels (HP:0007843)1.87497230
78Abnormality of T cell number (HP:0011839)1.86463239
79Abnormality of the fovea (HP:0000493)1.85308565
80Absent thumb (HP:0009777)1.85248395
81T lymphocytopenia (HP:0005403)1.83414119
82Hypoplasia of the pons (HP:0012110)1.81864932
83Aplasia/Hypoplasia of the fovea (HP:0008060)1.80243508
84Hypoplasia of the fovea (HP:0007750)1.80243508
85Cystic liver disease (HP:0006706)1.80112292
86Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.79299104
87Hypoproteinemia (HP:0003075)1.78408492
88CNS demyelination (HP:0007305)1.77017955
89Anhidrosis (HP:0000970)1.76442808
90Increased muscle lipid content (HP:0009058)1.75394552
91Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.74899888
92Type 2 muscle fiber atrophy (HP:0003554)1.74049678
93Abnormality of the renal medulla (HP:0100957)1.73564722
94Abnormality of the renal collecting system (HP:0004742)1.73238002
95Leukodystrophy (HP:0002415)1.72869505
96Abnormal albumin level (HP:0012116)1.72118476
97Hypoalbuminemia (HP:0003073)1.72118476
98Decreased central vision (HP:0007663)1.70990852
99Absent septum pellucidum (HP:0001331)1.68325303
100Degeneration of the lateral corticospinal tracts (HP:0002314)1.67585135

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K24.28810007
2EIF2AK33.75366979
3STK163.74732676
4MAPKAPK33.30084604
5ZAK2.59920305
6BMPR1B2.58105901
7TLK12.56189624
8TAOK32.35850368
9WNK42.35323603
10ADRBK22.24921478
11FRK2.16770988
12BCKDK2.16542680
13TSSK62.11968528
14TRIM282.02043089
15PHKG11.99452537
16PHKG21.99452537
17VRK21.94173265
18EIF2AK11.88039027
19PINK11.84315067
20GRK11.66747244
21OBSCN1.66348607
22CAMKK21.48354661
23KDR1.40081163
24MAPKAPK51.39838353
25WNK31.35857553
26MST41.26414739
27PLK41.21573415
28FES1.17856402
29EPHA31.17250076
30MAPK131.13151676
31TEC1.11091414
32TXK1.10822181
33VRK11.10732267
34TIE11.09060459
35TAF11.08623940
36EIF2AK21.06195558
37OXSR11.05099808
38CSNK1G31.04990292
39NUAK11.03916225
40PDK20.96713516
41PIM20.94139268
42MET0.93938600
43MAP3K40.93368317
44ITK0.91068084
45CSNK1G20.90701872
46STK390.88202423
47PLK20.86450484
48PRKCQ0.86390932
49PLK30.82607597
50INSRR0.79708618
51CSNK1G10.78291412
52MKNK10.75512611
53MAP3K130.74915598
54STK240.71592915
55MAP2K70.70845260
56KIT0.70796836
57PRKD30.70518511
58DYRK20.70039266
59MATK0.67945890
60PKN10.67311947
61CSNK1A1L0.66883837
62NTRK10.66372828
63CDK190.65128609
64SYK0.63045444
65TRPM70.59173457
66MAP4K10.58551799
67PRKCI0.57775183
68MAP3K110.55264145
69ARAF0.51467395
70RPS6KA50.49508009
71NEK60.49209480
72IKBKB0.48651331
73DYRK1B0.48359980
74MAP3K140.48286827
75ERBB30.46843520
76GRK50.42610121
77TNK20.42322141
78CAMK10.41919491
79NLK0.39284020
80MAP2K60.38219158
81BCR0.38097527
82ALK0.37184338
83SRPK10.37058647
84CSNK1A10.36712662
85CHUK0.35390463
86PRKCE0.33610685
87PRKCG0.32552195
88AURKA0.30379877
89RPS6KB20.30045636
90CAMK2A0.29181944
91PRKACA0.28132650
92CHEK20.27599740
93STK110.27300466
94IGF1R0.27019755
95NTRK20.26522686
96CDK80.26364223
97PLK10.26123832
98PRKCA0.25658120
99PRKCZ0.24773838
100CSNK2A20.23504999

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.68986225
2Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.95046860
3Oxidative phosphorylation_Homo sapiens_hsa001902.82339999
4Primary immunodeficiency_Homo sapiens_hsa053402.51271796
5Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.47225699
6Parkinsons disease_Homo sapiens_hsa050122.41972300
7Linoleic acid metabolism_Homo sapiens_hsa005912.16105965
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.14625134
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.04357962
10alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.00262833
11Propanoate metabolism_Homo sapiens_hsa006401.92684453
12Primary bile acid biosynthesis_Homo sapiens_hsa001201.84075419
13Basal transcription factors_Homo sapiens_hsa030221.82247415
14Autoimmune thyroid disease_Homo sapiens_hsa053201.82123522
15Allograft rejection_Homo sapiens_hsa053301.79894427
16RNA polymerase_Homo sapiens_hsa030201.79446790
17Asthma_Homo sapiens_hsa053101.78170056
18Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.74220303
19Protein export_Homo sapiens_hsa030601.66193897
20Selenocompound metabolism_Homo sapiens_hsa004501.62802571
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.57022352
22Intestinal immune network for IgA production_Homo sapiens_hsa046721.56796559
23Phototransduction_Homo sapiens_hsa047441.56074547
24RNA degradation_Homo sapiens_hsa030181.55089963
25Nitrogen metabolism_Homo sapiens_hsa009101.51708797
26Ribosome_Homo sapiens_hsa030101.49904624
27Caffeine metabolism_Homo sapiens_hsa002321.48976360
28Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.48382054
29Huntingtons disease_Homo sapiens_hsa050161.47786550
30Antigen processing and presentation_Homo sapiens_hsa046121.46765943
31Peroxisome_Homo sapiens_hsa041461.40597214
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.36716112
33Alzheimers disease_Homo sapiens_hsa050101.35289942
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.32651377
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.30961213
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.30198867
37Sulfur metabolism_Homo sapiens_hsa009201.29136715
38Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.26547192
39Type I diabetes mellitus_Homo sapiens_hsa049401.25593548
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.24765678
41Graft-versus-host disease_Homo sapiens_hsa053321.24124958
42Cardiac muscle contraction_Homo sapiens_hsa042601.20266010
43Butanoate metabolism_Homo sapiens_hsa006501.16330075
44Tryptophan metabolism_Homo sapiens_hsa003801.15109390
45Collecting duct acid secretion_Homo sapiens_hsa049661.13703405
46Rheumatoid arthritis_Homo sapiens_hsa053231.11375802
47RNA transport_Homo sapiens_hsa030131.09047593
482-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.07146907
49One carbon pool by folate_Homo sapiens_hsa006701.04708745
50Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.03174449
51Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.02639958
52Chemical carcinogenesis_Homo sapiens_hsa052041.01323173
53Steroid biosynthesis_Homo sapiens_hsa001001.01299393
54Regulation of autophagy_Homo sapiens_hsa041401.00270284
55Homologous recombination_Homo sapiens_hsa034400.94922663
56Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.94058048
57Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.92787229
58Arachidonic acid metabolism_Homo sapiens_hsa005900.92716162
59Steroid hormone biosynthesis_Homo sapiens_hsa001400.86710421
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.85207545
61Ether lipid metabolism_Homo sapiens_hsa005650.83230599
62Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.78671613
63Fatty acid elongation_Homo sapiens_hsa000620.78623103
64Retinol metabolism_Homo sapiens_hsa008300.77676777
65Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.75316585
66Hematopoietic cell lineage_Homo sapiens_hsa046400.74281415
67Ovarian steroidogenesis_Homo sapiens_hsa049130.67622310
68Purine metabolism_Homo sapiens_hsa002300.66459426
69Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.65534398
70Metabolic pathways_Homo sapiens_hsa011000.65442779
71Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.65236614
72Nucleotide excision repair_Homo sapiens_hsa034200.63848510
73Fanconi anemia pathway_Homo sapiens_hsa034600.63238620
74Arginine biosynthesis_Homo sapiens_hsa002200.61855288
75Spliceosome_Homo sapiens_hsa030400.60449725
76Fat digestion and absorption_Homo sapiens_hsa049750.60246340
77Olfactory transduction_Homo sapiens_hsa047400.59941066
78beta-Alanine metabolism_Homo sapiens_hsa004100.58082289
79Fatty acid degradation_Homo sapiens_hsa000710.54448805
80Base excision repair_Homo sapiens_hsa034100.52189963
81Sulfur relay system_Homo sapiens_hsa041220.49469225
82T cell receptor signaling pathway_Homo sapiens_hsa046600.49336377
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48039541
84NF-kappa B signaling pathway_Homo sapiens_hsa040640.47506753
85Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47403271
86Pyrimidine metabolism_Homo sapiens_hsa002400.43293088
87Morphine addiction_Homo sapiens_hsa050320.42773474
88Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36748179
89Pyruvate metabolism_Homo sapiens_hsa006200.36265114
90Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.34234168
91Arginine and proline metabolism_Homo sapiens_hsa003300.34037967
92Viral myocarditis_Homo sapiens_hsa054160.33748753
93Maturity onset diabetes of the young_Homo sapiens_hsa049500.31575591
94Nicotine addiction_Homo sapiens_hsa050330.31196935
95Tyrosine metabolism_Homo sapiens_hsa003500.30697497
96Carbon metabolism_Homo sapiens_hsa012000.30680328
97Synaptic vesicle cycle_Homo sapiens_hsa047210.30046163
98Starch and sucrose metabolism_Homo sapiens_hsa005000.29594305
99Salivary secretion_Homo sapiens_hsa049700.27597154
100Systemic lupus erythematosus_Homo sapiens_hsa053220.26246808

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »