Rank | Gene Set | Z-score |
---|---|---|
1 | axon ensheathment in central nervous system (GO:0032291) | 7.61248545 |
2 | central nervous system myelination (GO:0022010) | 7.61248545 |
3 | negative regulation of neurotransmitter secretion (GO:0046929) | 4.76802141 |
4 | behavioral response to nicotine (GO:0035095) | 4.56058530 |
5 | fatty acid elongation (GO:0030497) | 4.40745039 |
6 | myelination (GO:0042552) | 4.37072085 |
7 | ensheathment of neurons (GO:0007272) | 4.35569660 |
8 | axon ensheathment (GO:0008366) | 4.35569660 |
9 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.17953806 |
10 | negative regulation of neurotransmitter transport (GO:0051589) | 4.01621278 |
11 | apical protein localization (GO:0045176) | 3.98451262 |
12 | photoreceptor cell differentiation (GO:0046530) | 3.96232880 |
13 | eye photoreceptor cell differentiation (GO:0001754) | 3.96232880 |
14 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.95341209 |
15 | endocrine pancreas development (GO:0031018) | 3.90181431 |
16 | nucleobase catabolic process (GO:0046113) | 3.88597017 |
17 | ER overload response (GO:0006983) | 3.87415260 |
18 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.87185484 |
19 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.83175906 |
20 | axonal fasciculation (GO:0007413) | 3.82456153 |
21 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.72523510 |
22 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.70910846 |
23 | gamma-aminobutyric acid transport (GO:0015812) | 3.70298137 |
24 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.68321231 |
25 | asymmetric protein localization (GO:0008105) | 3.67254305 |
26 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.67024265 |
27 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.65150829 |
28 | synaptic transmission, glutamatergic (GO:0035249) | 3.59495778 |
29 | glutamate receptor signaling pathway (GO:0007215) | 3.58584996 |
30 | neuron recognition (GO:0008038) | 3.57170912 |
31 | presynaptic membrane organization (GO:0097090) | 3.57158761 |
32 | proline transport (GO:0015824) | 3.49745814 |
33 | magnesium ion transport (GO:0015693) | 3.45112506 |
34 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.43792557 |
35 | presynaptic membrane assembly (GO:0097105) | 3.41411449 |
36 | response to redox state (GO:0051775) | 3.38023717 |
37 | oligodendrocyte differentiation (GO:0048709) | 3.37036463 |
38 | forebrain neuron differentiation (GO:0021879) | 3.34689928 |
39 | postsynaptic membrane organization (GO:0001941) | 3.29144665 |
40 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.27882942 |
41 | neuron-neuron synaptic transmission (GO:0007270) | 3.27601786 |
42 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 3.25930190 |
43 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.25600739 |
44 | glycerophospholipid catabolic process (GO:0046475) | 3.25463387 |
45 | Golgi transport vesicle coating (GO:0048200) | 3.24154511 |
46 | COPI coating of Golgi vesicle (GO:0048205) | 3.24154511 |
47 | startle response (GO:0001964) | 3.23816574 |
48 | synapse assembly (GO:0007416) | 3.22878372 |
49 | response to pheromone (GO:0019236) | 3.22830893 |
50 | glandular epithelial cell differentiation (GO:0002067) | 3.21925024 |
51 | astrocyte differentiation (GO:0048708) | 3.20285398 |
52 | protein palmitoylation (GO:0018345) | 3.19401776 |
53 | neuronal action potential (GO:0019228) | 3.17083995 |
54 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.16337600 |
55 | myelin maintenance (GO:0043217) | 3.15954263 |
56 | neuromuscular synaptic transmission (GO:0007274) | 3.15307529 |
57 | negative regulation of JUN kinase activity (GO:0043508) | 3.14427726 |
58 | glutamate secretion (GO:0014047) | 3.14218816 |
59 | membrane depolarization during action potential (GO:0086010) | 3.14047589 |
60 | urinary tract smooth muscle contraction (GO:0014848) | 3.12814761 |
61 | response to lipoprotein particle (GO:0055094) | 3.10552271 |
62 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.10211481 |
63 | peptide hormone processing (GO:0016486) | 3.01767569 |
64 | establishment of mitochondrion localization (GO:0051654) | 2.97462549 |
65 | neuron cell-cell adhesion (GO:0007158) | 2.96870354 |
66 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.96858779 |
67 | cranial nerve development (GO:0021545) | 2.95158972 |
68 | regulation of collateral sprouting (GO:0048670) | 2.94582448 |
69 | cerebellar granule cell differentiation (GO:0021707) | 2.94498025 |
70 | transmission of nerve impulse (GO:0019226) | 2.93705048 |
71 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.92602370 |
72 | detection of light stimulus involved in visual perception (GO:0050908) | 2.92602370 |
73 | negative regulation of dendrite development (GO:2000171) | 2.91939257 |
74 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.91813235 |
75 | detection of calcium ion (GO:0005513) | 2.91726352 |
76 | neurotransmitter secretion (GO:0007269) | 2.90249457 |
77 | adult walking behavior (GO:0007628) | 2.89375310 |
78 | protein localization to synapse (GO:0035418) | 2.89250164 |
79 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.87824875 |
80 | insulin secretion (GO:0030073) | 2.86559243 |
81 | auditory behavior (GO:0031223) | 2.84006674 |
82 | reflex (GO:0060004) | 2.82509739 |
83 | cellular ketone body metabolic process (GO:0046950) | 2.82171966 |
84 | inositol phosphate catabolic process (GO:0071545) | 2.81626143 |
85 | creatine metabolic process (GO:0006600) | 2.80798789 |
86 | glycosphingolipid biosynthetic process (GO:0006688) | 2.79559894 |
87 | regulation of transcription involved in cell fate commitment (GO:0060850) | 2.79400693 |
88 | protein polyglutamylation (GO:0018095) | 2.79389168 |
89 | response to hepatocyte growth factor (GO:0035728) | 2.79280063 |
90 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 2.79280063 |
91 | regulation of respiratory system process (GO:0044065) | 2.78049153 |
92 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 2.77781171 |
93 | neuronal action potential propagation (GO:0019227) | 2.75697855 |
94 | serotonin metabolic process (GO:0042428) | 2.75351153 |
95 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.75339750 |
96 | dendritic spine morphogenesis (GO:0060997) | 2.75273611 |
97 | vocalization behavior (GO:0071625) | 2.75120027 |
98 | L-amino acid import (GO:0043092) | 2.74444377 |
99 | spinal cord motor neuron differentiation (GO:0021522) | 2.74406320 |
100 | behavioral response to ethanol (GO:0048149) | 2.73600830 |
101 | response to methylmercury (GO:0051597) | 2.73540490 |
102 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.73009260 |
103 | cholesterol biosynthetic process (GO:0006695) | 2.72093059 |
104 | dendrite morphogenesis (GO:0048813) | 2.71395252 |
105 | synaptic vesicle exocytosis (GO:0016079) | 2.70938653 |
106 | protein maturation by protein folding (GO:0022417) | 2.68715360 |
107 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.67580163 |
108 | locomotory exploration behavior (GO:0035641) | 2.67516469 |
109 | primary amino compound metabolic process (GO:1901160) | 2.67145011 |
110 | dopamine biosynthetic process (GO:0042416) | 2.66033418 |
111 | calcium ion import (GO:0070509) | 2.64922219 |
112 | signal peptide processing (GO:0006465) | 2.64669934 |
113 | positive regulation of insulin secretion (GO:0032024) | 2.64294791 |
114 | retinal ganglion cell axon guidance (GO:0031290) | 2.64240607 |
115 | adult behavior (GO:0030534) | 2.63418456 |
116 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.62755749 |
117 | positive regulation of action potential (GO:0045760) | 2.62560110 |
118 | type B pancreatic cell development (GO:0003323) | 2.62504257 |
119 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.62479793 |
120 | protein localization to cilium (GO:0061512) | 2.61371689 |
121 | regulation of neurotransmitter transport (GO:0051588) | 2.61274904 |
122 | action potential (GO:0001508) | 2.60232547 |
123 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.60221896 |
124 | long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) | 2.58806776 |
125 | nucleotide transmembrane transport (GO:1901679) | 2.58717278 |
126 | response to auditory stimulus (GO:0010996) | 2.57691373 |
127 | negative regulation of protein localization to cell surface (GO:2000009) | 2.57309173 |
128 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.57294998 |
129 | positive regulation of neurotransmitter transport (GO:0051590) | 2.56966107 |
130 | response to dietary excess (GO:0002021) | 2.56961711 |
131 | regulation of neurotransmitter uptake (GO:0051580) | 2.56687951 |
132 | neuron fate specification (GO:0048665) | 2.56612799 |
133 | regulation of synapse structural plasticity (GO:0051823) | 2.55415832 |
134 | righting reflex (GO:0060013) | 2.55181801 |
135 | regulation of cilium movement (GO:0003352) | 2.54869140 |
136 | nerve growth factor signaling pathway (GO:0038180) | 2.54817343 |
137 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.54394879 |
138 | regulation of action potential (GO:0098900) | 2.54065637 |
139 | tachykinin receptor signaling pathway (GO:0007217) | 2.53937131 |
140 | ganglion development (GO:0061548) | 2.53245804 |
141 | mechanosensory behavior (GO:0007638) | 2.52924853 |
142 | central nervous system neuron axonogenesis (GO:0021955) | 2.52803193 |
143 | mating behavior (GO:0007617) | 2.52164711 |
144 | regulation of neurotransmitter secretion (GO:0046928) | 2.52088707 |
145 | substantia nigra development (GO:0021762) | 2.51411076 |
146 | ear development (GO:0043583) | 2.50701146 |
147 | astrocyte development (GO:0014002) | 2.50685322 |
148 | adult locomotory behavior (GO:0008344) | 2.50298540 |
149 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.49904093 |
150 | membrane hyperpolarization (GO:0060081) | 2.49649752 |
151 | regulation of insulin secretion (GO:0050796) | 2.49591083 |
152 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.49000776 |
153 | regulation of postsynaptic membrane potential (GO:0060078) | 2.48792495 |
154 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.48738376 |
155 | dentate gyrus development (GO:0021542) | 2.48619657 |
156 | nonmotile primary cilium assembly (GO:0035058) | 2.48409074 |
157 | negative regulation of axonogenesis (GO:0050771) | 2.46075411 |
158 | neuron fate determination (GO:0048664) | 2.45520821 |
159 | regulation of autophagic vacuole assembly (GO:2000785) | 2.45044547 |
160 | GPI anchor metabolic process (GO:0006505) | 2.43877967 |
161 | regulation of dopamine metabolic process (GO:0042053) | 2.43458611 |
162 | regulation of catecholamine metabolic process (GO:0042069) | 2.43458611 |
163 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.43050251 |
164 | positive regulation of glial cell differentiation (GO:0045687) | 2.42596600 |
165 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.41987081 |
166 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.41987081 |
167 | protein targeting to Golgi (GO:0000042) | 2.39485610 |
168 | Golgi to plasma membrane protein transport (GO:0043001) | 2.38415145 |
169 | neuronal ion channel clustering (GO:0045161) | 2.37570865 |
170 | glycosylceramide metabolic process (GO:0006677) | 2.37414085 |
171 | cell differentiation in hindbrain (GO:0021533) | 2.36123944 |
172 | synaptic vesicle maturation (GO:0016188) | 2.35747181 |
173 | amyloid precursor protein metabolic process (GO:0042982) | 2.35135682 |
174 | Golgi to endosome transport (GO:0006895) | 2.35034776 |
175 | potassium ion homeostasis (GO:0055075) | 2.34767548 |
176 | chemosensory behavior (GO:0007635) | 2.32495332 |
Rank | Gene Set | Z-score |
---|---|---|
1 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.52683145 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.59188546 |
3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.40596033 |
4 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.35246215 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.33027582 |
6 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.28241236 |
7 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.14002713 |
8 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.07900257 |
9 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 2.06845132 |
10 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.06218135 |
11 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.05769814 |
12 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.04931552 |
13 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.04785931 |
14 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.04454123 |
15 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.96046674 |
16 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.95480218 |
17 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.94838769 |
18 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.89510531 |
19 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.89032961 |
20 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.87145963 |
21 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.85712460 |
22 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.83689560 |
23 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.81213611 |
24 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.80198642 |
25 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.78520759 |
26 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.78520759 |
27 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.75995905 |
28 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.74105146 |
29 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.73390555 |
30 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.71115424 |
31 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.70409973 |
32 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.69084552 |
33 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.68663940 |
34 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.65824052 |
35 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.57261190 |
36 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.57093331 |
37 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.56021614 |
38 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.53336869 |
39 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.53015349 |
40 | AR_25329375_ChIP-Seq_VCAP_Human | 1.52475508 |
41 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.51437671 |
42 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.50815688 |
43 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.50815688 |
44 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.50490135 |
45 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.48618815 |
46 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.47767734 |
47 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.47656573 |
48 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.45654219 |
49 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.45239685 |
50 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.44369800 |
51 | EWS_26573619_Chip-Seq_HEK293_Human | 1.43765442 |
52 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.42842106 |
53 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.42301932 |
54 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.40765068 |
55 | VDR_22108803_ChIP-Seq_LS180_Human | 1.39590082 |
56 | * FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.36408059 |
57 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.35618241 |
58 | P300_19829295_ChIP-Seq_ESCs_Human | 1.35119283 |
59 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.35100622 |
60 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.33177102 |
61 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.32780015 |
62 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.31780966 |
63 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.31462270 |
64 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.29713576 |
65 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.29227936 |
66 | TCF4_23295773_ChIP-Seq_U87_Human | 1.28988298 |
67 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.27866188 |
68 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.27866188 |
69 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.25471002 |
70 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25463225 |
71 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.23713818 |
72 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.23030004 |
73 | FUS_26573619_Chip-Seq_HEK293_Human | 1.22940466 |
74 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.22254060 |
75 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.20924364 |
76 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.20261267 |
77 | * RNF2_27304074_Chip-Seq_NSC_Mouse | 1.18510446 |
78 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.18321865 |
79 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.17876096 |
80 | * PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.16698942 |
81 | * CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.14907988 |
82 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.14753619 |
83 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.14683458 |
84 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.12984139 |
85 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.12731786 |
86 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.12725143 |
87 | * SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.11946321 |
88 | * PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.10269303 |
89 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.10183712 |
90 | * EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.09022889 |
91 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.08995462 |
92 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.08694705 |
93 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.08233605 |
94 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.07494556 |
95 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06905498 |
96 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.06801714 |
97 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.05697686 |
98 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.04809862 |
99 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.04368691 |
100 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.04205600 |
101 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.03950201 |
102 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 1.03371165 |
103 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.02982521 |
104 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02830779 |
105 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.01753546 |
106 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.01406080 |
107 | * P300_18555785_Chip-Seq_ESCs_Mouse | 1.01247251 |
108 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.01015247 |
109 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.00598504 |
110 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.00147230 |
111 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.99864735 |
112 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.99809458 |
113 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 0.99232685 |
114 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.99135903 |
115 | * STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.97515157 |
116 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.96982475 |
117 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.96660940 |
118 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.95691107 |
119 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.95584202 |
120 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.95375668 |
121 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.95284699 |
122 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.94547191 |
123 | * SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.94037574 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004043_abnormal_pH_regulation | 3.24186644 |
2 | MP0004270_analgesia | 3.20786440 |
3 | MP0000920_abnormal_myelination | 3.19894194 |
4 | MP0006072_abnormal_retinal_apoptosis | 2.79315693 |
5 | MP0001968_abnormal_touch/_nociception | 2.49753578 |
6 | MP0003183_abnormal_peptide_metabolism | 2.49053818 |
7 | MP0000013_abnormal_adipose_tissue | 2.43837204 |
8 | MP0009780_abnormal_chondrocyte_physiolo | 2.40836216 |
9 | MP0010386_abnormal_urinary_bladder | 2.39579845 |
10 | MP0005551_abnormal_eye_electrophysiolog | 2.27697469 |
11 | MP0003195_calcinosis | 2.23548394 |
12 | MP0002272_abnormal_nervous_system | 2.18933029 |
13 | MP0000569_abnormal_digit_pigmentation | 2.18459408 |
14 | MP0004859_abnormal_synaptic_plasticity | 2.15433961 |
15 | MP0003283_abnormal_digestive_organ | 2.09861427 |
16 | MP0003880_abnormal_central_pattern | 2.08636107 |
17 | MP0001486_abnormal_startle_reflex | 2.05421979 |
18 | MP0002064_seizures | 1.96583829 |
19 | MP0002909_abnormal_adrenal_gland | 1.95289186 |
20 | MP0004742_abnormal_vestibular_system | 1.93698035 |
21 | MP0004885_abnormal_endolymph | 1.93391423 |
22 | MP0003634_abnormal_glial_cell | 1.89262112 |
23 | MP0009046_muscle_twitch | 1.87373300 |
24 | MP0003635_abnormal_synaptic_transmissio | 1.87365409 |
25 | MP0003690_abnormal_glial_cell | 1.85281415 |
26 | MP0002734_abnormal_mechanical_nocicepti | 1.84886656 |
27 | MP0008877_abnormal_DNA_methylation | 1.84659685 |
28 | MP0005379_endocrine/exocrine_gland_phen | 1.82718204 |
29 | MP0003950_abnormal_plasma_membrane | 1.82707971 |
30 | MP0005645_abnormal_hypothalamus_physiol | 1.81547761 |
31 | MP0005646_abnormal_pituitary_gland | 1.79253121 |
32 | MP0001501_abnormal_sleep_pattern | 1.77636826 |
33 | MP0002693_abnormal_pancreas_physiology | 1.76394045 |
34 | MP0002229_neurodegeneration | 1.76122986 |
35 | MP0005253_abnormal_eye_physiology | 1.75350740 |
36 | MP0001502_abnormal_circadian_rhythm | 1.72048058 |
37 | MP0001944_abnormal_pancreas_morphology | 1.71323754 |
38 | MP0002736_abnormal_nociception_after | 1.69652751 |
39 | MP0000778_abnormal_nervous_system | 1.69419387 |
40 | MP0004145_abnormal_muscle_electrophysio | 1.67168377 |
41 | MP0000631_abnormal_neuroendocrine_gland | 1.65585395 |
42 | MP0004142_abnormal_muscle_tone | 1.64046933 |
43 | MP0000462_abnormal_digestive_system | 1.61347620 |
44 | MP0001529_abnormal_vocalization | 1.59200920 |
45 | MP0000955_abnormal_spinal_cord | 1.57837630 |
46 | MP0005423_abnormal_somatic_nervous | 1.56970825 |
47 | MP0001346_abnormal_lacrimal_gland | 1.55407636 |
48 | MP0003329_amyloid_beta_deposits | 1.53009592 |
49 | MP0009745_abnormal_behavioral_response | 1.51835405 |
50 | MP0001485_abnormal_pinna_reflex | 1.50376725 |
51 | MP0002638_abnormal_pupillary_reflex | 1.49263225 |
52 | MP0002572_abnormal_emotion/affect_behav | 1.46916417 |
53 | MP0002877_abnormal_melanocyte_morpholog | 1.45870704 |
54 | MP0000003_abnormal_adipose_tissue | 1.44945207 |
55 | MP0002822_catalepsy | 1.44457677 |
56 | MP0008569_lethality_at_weaning | 1.41504554 |
57 | MP0002063_abnormal_learning/memory/cond | 1.40385911 |
58 | MP0002067_abnormal_sensory_capabilities | 1.39240579 |
59 | MP0002090_abnormal_vision | 1.38824739 |
60 | MP0001661_extended_life_span | 1.38666796 |
61 | MP0002184_abnormal_innervation | 1.37917383 |
62 | MP0002882_abnormal_neuron_morphology | 1.37755025 |
63 | MP0001299_abnormal_eye_distance/ | 1.37743789 |
64 | MP0005171_absent_coat_pigmentation | 1.37560607 |
65 | MP0001905_abnormal_dopamine_level | 1.37319132 |
66 | MP0003121_genomic_imprinting | 1.34175580 |
67 | MP0004133_heterotaxia | 1.30890891 |
68 | MP0005220_abnormal_exocrine_pancreas | 1.28356478 |
69 | MP0004147_increased_porphyrin_level | 1.21989181 |
70 | MP0003632_abnormal_nervous_system | 1.20517379 |
71 | MP0006292_abnormal_olfactory_placode | 1.19030421 |
72 | MP0001986_abnormal_taste_sensitivity | 1.18714522 |
73 | MP0001970_abnormal_pain_threshold | 1.18582315 |
74 | MP0003633_abnormal_nervous_system | 1.17100147 |
75 | MP0002557_abnormal_social/conspecific_i | 1.16115043 |
76 | MP0002733_abnormal_thermal_nociception | 1.14377086 |
77 | MP0002066_abnormal_motor_capabilities/c | 1.12820400 |
78 | MP0000678_abnormal_parathyroid_gland | 1.12680465 |
79 | MP0003890_abnormal_embryonic-extraembry | 1.11910103 |
80 | MP0002876_abnormal_thyroid_physiology | 1.11434414 |
81 | MP0005386_behavior/neurological_phenoty | 1.11187798 |
82 | MP0004924_abnormal_behavior | 1.11187798 |
83 | MP0008872_abnormal_physiological_respon | 1.10929709 |
84 | MP0005195_abnormal_posterior_eye | 1.10319297 |
85 | MP0002752_abnormal_somatic_nervous | 1.06077975 |
86 | MP0003631_nervous_system_phenotype | 1.05727436 |
87 | MP0002234_abnormal_pharynx_morphology | 1.05345933 |
88 | MP0003879_abnormal_hair_cell | 1.04142648 |
89 | MP0005187_abnormal_penis_morphology | 1.02572404 |
90 | MP0008995_early_reproductive_senescence | 1.00991987 |
91 | MP0002653_abnormal_ependyma_morphology | 0.99893435 |
92 | MP0005409_darkened_coat_color | 0.99317326 |
93 | MP0001963_abnormal_hearing_physiology | 0.99001202 |
94 | MP0001984_abnormal_olfaction | 0.97025989 |
95 | MP0003172_abnormal_lysosome_physiology | 0.96594557 |
96 | MP0002078_abnormal_glucose_homeostasis | 0.95295700 |
97 | MP0003122_maternal_imprinting | 0.94154141 |
98 | MP0001188_hyperpigmentation | 0.93809631 |
99 | MP0002163_abnormal_gland_morphology | 0.92912540 |
100 | MP0001440_abnormal_grooming_behavior | 0.91341869 |
101 | MP0004811_abnormal_neuron_physiology | 0.91302845 |
102 | MP0002102_abnormal_ear_morphology | 0.90941296 |
103 | MP0002928_abnormal_bile_duct | 0.89637552 |
104 | MP0005058_abnormal_lysosome_morphology | 0.89327027 |
105 | MP0003123_paternal_imprinting | 0.88906797 |
106 | MP0002152_abnormal_brain_morphology | 0.87421952 |
107 | MP0000566_synostosis | 0.84804735 |
108 | MP0002837_dystrophic_cardiac_calcinosis | 0.83404225 |
109 | MP0004134_abnormal_chest_morphology | 0.81374951 |
110 | MP0002160_abnormal_reproductive_system | 0.81187246 |
111 | MP0003787_abnormal_imprinting | 0.81092450 |
112 | MP0005410_abnormal_fertilization | 0.80375893 |
113 | MP0008789_abnormal_olfactory_epithelium | 0.79632815 |
114 | MP0002069_abnormal_eating/drinking_beha | 0.78585752 |
115 | MP0002751_abnormal_autonomic_nervous | 0.78050969 |
116 | MP0005535_abnormal_body_temperature | 0.76104482 |
117 | MP0003119_abnormal_digestive_system | 0.74680426 |
118 | MP0002735_abnormal_chemical_nociception | 0.74606831 |
119 | MP0000427_abnormal_hair_cycle | 0.74144413 |
120 | MP0003137_abnormal_impulse_conducting | 0.72686614 |
121 | MP0005499_abnormal_olfactory_system | 0.71839094 |
122 | MP0005394_taste/olfaction_phenotype | 0.71839094 |
123 | MP0005391_vision/eye_phenotype | 0.70056839 |
124 | MP0006276_abnormal_autonomic_nervous | 0.69711348 |
125 | MP0000026_abnormal_inner_ear | 0.69551325 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Neurofibrillary tangles (HP:0002185) | 4.48227390 |
2 | Hyperinsulinemic hypoglycemia (HP:0000825) | 4.29117762 |
3 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 4.26903452 |
4 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 4.26903452 |
5 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 4.16138788 |
6 | Focal motor seizures (HP:0011153) | 4.11504974 |
7 | Hypoglycemic seizures (HP:0002173) | 3.99415758 |
8 | Large for gestational age (HP:0001520) | 3.72658765 |
9 | Focal seizures (HP:0007359) | 3.56082438 |
10 | Symptomatic seizures (HP:0011145) | 3.55313062 |
11 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.46310935 |
12 | Congenital stationary night blindness (HP:0007642) | 3.42341205 |
13 | Anteriorly placed anus (HP:0001545) | 3.41891432 |
14 | Febrile seizures (HP:0002373) | 3.39015864 |
15 | Pheochromocytoma (HP:0002666) | 3.37511771 |
16 | Hyperventilation (HP:0002883) | 3.37451495 |
17 | Abnormality of the corticospinal tract (HP:0002492) | 3.26935722 |
18 | Genetic anticipation (HP:0003743) | 3.21222575 |
19 | Broad-based gait (HP:0002136) | 3.15744274 |
20 | Abnormality of endocrine pancreas physiology (HP:0012093) | 3.15193546 |
21 | Abnormality of the pancreatic islet cells (HP:0006476) | 3.15193546 |
22 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.11736983 |
23 | Supranuclear gaze palsy (HP:0000605) | 3.10227225 |
24 | Nephronophthisis (HP:0000090) | 3.07744091 |
25 | Cerebral inclusion bodies (HP:0100314) | 3.02906446 |
26 | Split foot (HP:0001839) | 2.99651941 |
27 | Abnormality of midbrain morphology (HP:0002418) | 2.98708165 |
28 | Molar tooth sign on MRI (HP:0002419) | 2.98708165 |
29 | Gaze-evoked nystagmus (HP:0000640) | 2.94893399 |
30 | Retinal dysplasia (HP:0007973) | 2.94458783 |
31 | Limb dystonia (HP:0002451) | 2.91586392 |
32 | Agitation (HP:0000713) | 2.84572041 |
33 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.84485464 |
34 | Hypoplasia of the fovea (HP:0007750) | 2.84485464 |
35 | Increased circulating renin level (HP:0000848) | 2.82487606 |
36 | Spastic gait (HP:0002064) | 2.81721103 |
37 | Neuroendocrine neoplasm (HP:0100634) | 2.81274478 |
38 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.80150912 |
39 | Alacrima (HP:0000522) | 2.75755183 |
40 | EEG with generalized epileptiform discharges (HP:0011198) | 2.72903879 |
41 | Intention tremor (HP:0002080) | 2.71918621 |
42 | Abnormality of the renal medulla (HP:0100957) | 2.67826916 |
43 | Pancreatic fibrosis (HP:0100732) | 2.67192940 |
44 | Dialeptic seizures (HP:0011146) | 2.64642558 |
45 | Epileptiform EEG discharges (HP:0011182) | 2.61683641 |
46 | Dysmetria (HP:0001310) | 2.60675685 |
47 | Pancreatic cysts (HP:0001737) | 2.60427680 |
48 | Hypsarrhythmia (HP:0002521) | 2.58225669 |
49 | Septo-optic dysplasia (HP:0100842) | 2.54339796 |
50 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.54013267 |
51 | Abnormality of the fovea (HP:0000493) | 2.52454236 |
52 | Epileptic encephalopathy (HP:0200134) | 2.49043848 |
53 | Nephrogenic diabetes insipidus (HP:0009806) | 2.48216910 |
54 | Thickened helices (HP:0000391) | 2.47656400 |
55 | Absent speech (HP:0001344) | 2.47225131 |
56 | Sensory axonal neuropathy (HP:0003390) | 2.46339597 |
57 | Polyphagia (HP:0002591) | 2.44926194 |
58 | Scanning speech (HP:0002168) | 2.44430257 |
59 | Action tremor (HP:0002345) | 2.43379581 |
60 | Onion bulb formation (HP:0003383) | 2.40675125 |
61 | Congenital sensorineural hearing impairment (HP:0008527) | 2.39353568 |
62 | Hepatoblastoma (HP:0002884) | 2.38048925 |
63 | Peripheral hypomyelination (HP:0007182) | 2.37152993 |
64 | True hermaphroditism (HP:0010459) | 2.36526967 |
65 | Hypothermia (HP:0002045) | 2.34520315 |
66 | Decreased circulating renin level (HP:0003351) | 2.33691306 |
67 | Abnormality of macular pigmentation (HP:0008002) | 2.32864475 |
68 | Hypoglycemic coma (HP:0001325) | 2.31259796 |
69 | Central scotoma (HP:0000603) | 2.31093531 |
70 | Generalized tonic-clonic seizures (HP:0002069) | 2.30598291 |
71 | Ankle clonus (HP:0011448) | 2.28447774 |
72 | Type II lissencephaly (HP:0007260) | 2.27671835 |
73 | Decreased lacrimation (HP:0000633) | 2.27398845 |
74 | Abnormal pancreas size (HP:0012094) | 2.27098014 |
75 | Absent septum pellucidum (HP:0001331) | 2.26324620 |
76 | Chronic hepatic failure (HP:0100626) | 2.25554944 |
77 | Inability to walk (HP:0002540) | 2.24377784 |
78 | Hyperkalemia (HP:0002153) | 2.19644210 |
79 | Parakeratosis (HP:0001036) | 2.18502568 |
80 | Abnormality of the renal cortex (HP:0011035) | 2.17720869 |
81 | Ketoacidosis (HP:0001993) | 2.17719799 |
82 | Cerebral hypomyelination (HP:0006808) | 2.17523543 |
83 | Absence seizures (HP:0002121) | 2.17235259 |
84 | Polydipsia (HP:0001959) | 2.16642002 |
85 | Abnormal drinking behavior (HP:0030082) | 2.16642002 |
86 | Abnormality of renin-angiotensin system (HP:0000847) | 2.13987976 |
87 | Visual hallucinations (HP:0002367) | 2.13333424 |
88 | Methylmalonic acidemia (HP:0002912) | 2.13178134 |
89 | Progressive cerebellar ataxia (HP:0002073) | 2.12374209 |
90 | Protruding tongue (HP:0010808) | 2.10788359 |
91 | Macroorchidism (HP:0000053) | 2.10016326 |
92 | Megalencephaly (HP:0001355) | 2.09130463 |
93 | Hemiparesis (HP:0001269) | 2.09109541 |
94 | Lissencephaly (HP:0001339) | 2.07709628 |
95 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.06136955 |
96 | Hypokalemia (HP:0002900) | 2.04190314 |
97 | Optic nerve hypoplasia (HP:0000609) | 2.03973329 |
98 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.03331367 |
99 | Hyperglycemia (HP:0003074) | 2.02546239 |
100 | Truncal ataxia (HP:0002078) | 2.01933814 |
101 | Abnormality of potassium homeostasis (HP:0011042) | 2.01542397 |
102 | Abolished electroretinogram (ERG) (HP:0000550) | 2.00909674 |
103 | Poor coordination (HP:0002370) | 2.00628256 |
104 | Prolonged QT interval (HP:0001657) | 2.00587145 |
105 | Abnormal eating behavior (HP:0100738) | 1.99842453 |
106 | Medial flaring of the eyebrow (HP:0010747) | 1.98878654 |
107 | Specific learning disability (HP:0001328) | 1.98118977 |
108 | Osteomalacia (HP:0002749) | 1.97920583 |
109 | Abnormality of the parathyroid morphology (HP:0011766) | 1.97558581 |
110 | Amblyopia (HP:0000646) | 1.97361279 |
111 | Abnormal auditory evoked potentials (HP:0006958) | 1.97272461 |
112 | Double outlet right ventricle (HP:0001719) | 1.94834591 |
113 | Congenital malformation of the right heart (HP:0011723) | 1.94834591 |
114 | Insidious onset (HP:0003587) | 1.94517149 |
115 | Termporal pattern (HP:0011008) | 1.94517149 |
116 | Vaginal atresia (HP:0000148) | 1.94401184 |
117 | Gait imbalance (HP:0002141) | 1.92349748 |
118 | Cupped ear (HP:0000378) | 1.92055748 |
119 | Hypomagnesemia (HP:0002917) | 1.91477135 |
120 | Clonus (HP:0002169) | 1.90330702 |
121 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.90078640 |
122 | Progressive inability to walk (HP:0002505) | 1.89909756 |
123 | Atonic seizures (HP:0010819) | 1.89671757 |
124 | Dysostosis multiplex (HP:0000943) | 1.88269635 |
125 | Intestinal atresia (HP:0011100) | 1.88214217 |
126 | Cortical visual impairment (HP:0100704) | 1.87858358 |
127 | Myokymia (HP:0002411) | 1.87525646 |
128 | Progressive neurologic deterioration (HP:0002344) | 1.87310934 |
129 | Retinal atrophy (HP:0001105) | 1.86600505 |
130 | Abnormality of the septum pellucidum (HP:0007375) | 1.86110257 |
131 | Genital tract atresia (HP:0001827) | 1.85974372 |
132 | Muscular hypotonia of the trunk (HP:0008936) | 1.85022067 |
133 | Cystic liver disease (HP:0006706) | 1.84686334 |
134 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.84038933 |
135 | Decreased central vision (HP:0007663) | 1.83140718 |
136 | Spastic tetraplegia (HP:0002510) | 1.83047981 |
137 | Anxiety (HP:0000739) | 1.82185632 |
138 | Postural tremor (HP:0002174) | 1.81461546 |
139 | Abnormality of the labia minora (HP:0012880) | 1.80560769 |
140 | Status epilepticus (HP:0002133) | 1.78490207 |
141 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.78481118 |
142 | Tubulointerstitial nephritis (HP:0001970) | 1.78384168 |
143 | Dysdiadochokinesis (HP:0002075) | 1.78051700 |
144 | Drooling (HP:0002307) | 1.77998164 |
145 | Excessive salivation (HP:0003781) | 1.77998164 |
146 | Neoplasm of the adrenal cortex (HP:0100641) | 1.77463841 |
147 | Aqueductal stenosis (HP:0002410) | 1.77104625 |
148 | Congenital primary aphakia (HP:0007707) | 1.76852845 |
149 | Pachygyria (HP:0001302) | 1.76817072 |
150 | Poor speech (HP:0002465) | 1.76091546 |
151 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 1.75619037 |
152 | Lower limb muscle weakness (HP:0007340) | 1.75228545 |
153 | Metabolic alkalosis (HP:0200114) | 1.75114355 |
154 | Abnormality of binocular vision (HP:0011514) | 1.73826763 |
155 | Diplopia (HP:0000651) | 1.73826763 |
156 | Choreoathetosis (HP:0001266) | 1.73739928 |
157 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.72630743 |
158 | Amyotrophic lateral sclerosis (HP:0007354) | 1.72051278 |
159 | Oligodactyly (hands) (HP:0001180) | 1.71867259 |
160 | Tubular atrophy (HP:0000092) | 1.70702111 |
161 | Abnormality of vitamin B metabolism (HP:0004340) | 1.70539132 |
162 | Widely spaced teeth (HP:0000687) | 1.70480401 |
163 | Thyroid-stimulating hormone excess (HP:0002925) | 1.68608322 |
164 | Fair hair (HP:0002286) | 1.67705792 |
165 | Progressive macrocephaly (HP:0004481) | 1.66753729 |
166 | Attenuation of retinal blood vessels (HP:0007843) | 1.66645320 |
Rank | Gene Set | Z-score |
---|---|---|
1 | INSRR | 4.31560366 |
2 | STK39 | 3.91885589 |
3 | OXSR1 | 3.04551686 |
4 | MAPK15 | 2.58126724 |
5 | EPHB1 | 2.56478266 |
6 | WNK4 | 2.53520640 |
7 | UHMK1 | 2.47711672 |
8 | ADRBK2 | 2.33202461 |
9 | DAPK2 | 2.26352549 |
10 | BCR | 2.18234378 |
11 | WNK1 | 2.08386371 |
12 | EPHA4 | 2.05261511 |
13 | HIPK2 | 2.00582295 |
14 | PRPF4B | 1.97863139 |
15 | PINK1 | 1.88332330 |
16 | WNK3 | 1.85528318 |
17 | PRKD3 | 1.79946641 |
18 | MAP4K2 | 1.79820082 |
19 | MAP3K2 | 1.79717295 |
20 | NEK6 | 1.78866418 |
21 | TNIK | 1.78546664 |
22 | PASK | 1.77996537 |
23 | PKN1 | 1.74479489 |
24 | PAK6 | 1.71021630 |
25 | MET | 1.70749717 |
26 | MAP2K7 | 1.66563520 |
27 | TAOK3 | 1.60791461 |
28 | NTRK1 | 1.55248018 |
29 | FGFR2 | 1.54433132 |
30 | MARK1 | 1.50872508 |
31 | PBK | 1.48936273 |
32 | SGK494 | 1.47736742 |
33 | SGK223 | 1.47736742 |
34 | CDK19 | 1.44196594 |
35 | CAMK2D | 1.42437670 |
36 | NTRK3 | 1.42210851 |
37 | GRK1 | 1.39846998 |
38 | MINK1 | 1.39466099 |
39 | CAMK2B | 1.36758426 |
40 | PNCK | 1.35568124 |
41 | MAPKAPK5 | 1.33202796 |
42 | CSNK1A1L | 1.32959907 |
43 | PAK3 | 1.32559393 |
44 | IRAK2 | 1.22746468 |
45 | BMPR1B | 1.14882351 |
46 | CSNK1G3 | 1.12564524 |
47 | CASK | 1.12046118 |
48 | ICK | 1.10600817 |
49 | SGK2 | 1.07280260 |
50 | EPHA3 | 1.05239498 |
51 | STK11 | 1.04176812 |
52 | ERBB3 | 1.03907763 |
53 | SIK2 | 0.97975233 |
54 | CDK5 | 0.96807266 |
55 | CSNK1G2 | 0.96454834 |
56 | PRKCH | 0.96320415 |
57 | BRD4 | 0.93873108 |
58 | IRAK1 | 0.93871749 |
59 | MARK2 | 0.93151808 |
60 | DYRK2 | 0.93013371 |
61 | CAMKK2 | 0.92496404 |
62 | PRKCE | 0.91826749 |
63 | ACVR1B | 0.90686032 |
64 | PLK2 | 0.88437225 |
65 | LIMK1 | 0.88211015 |
66 | CDC42BPA | 0.86553880 |
67 | FRK | 0.85322750 |
68 | CSNK1G1 | 0.85270168 |
69 | CLK1 | 0.84220231 |
70 | ROCK2 | 0.83138348 |
71 | DYRK1A | 0.82519481 |
72 | MKNK2 | 0.81113788 |
73 | CAMK1 | 0.81036986 |
74 | CAMKK1 | 0.78761421 |
75 | PRKD2 | 0.78529677 |
76 | MAP2K4 | 0.77941525 |
77 | CAMK2A | 0.73988443 |
78 | PRKCZ | 0.73635368 |
79 | MAPK13 | 0.73591232 |
80 | CAMK2G | 0.70904701 |
81 | CAMK1G | 0.68773941 |
82 | ADRBK1 | 0.66178784 |
83 | PHKG2 | 0.65302442 |
84 | PHKG1 | 0.65302442 |
85 | YES1 | 0.64395582 |
86 | CDK14 | 0.63823043 |
87 | TAOK1 | 0.61858477 |
88 | PRKG1 | 0.61841958 |
89 | PRKD1 | 0.61729107 |
90 | CSNK1A1 | 0.60671131 |
91 | NTRK2 | 0.58772719 |
92 | PTK2 | 0.58426318 |
93 | PTK2B | 0.57581971 |
94 | MAP3K1 | 0.57519501 |
95 | RPS6KA5 | 0.56830163 |
96 | CDK15 | 0.55905520 |
97 | KSR2 | 0.55038014 |
98 | CAMK4 | 0.54805761 |
99 | CSNK1D | 0.52949853 |
100 | CDK18 | 0.52737114 |
101 | PRKCQ | 0.52668174 |
102 | DYRK1B | 0.52494890 |
103 | STK38L | 0.51488788 |
104 | BMPR2 | 0.51101038 |
105 | MAP3K4 | 0.50489531 |
106 | AKT3 | 0.49886829 |
107 | TYRO3 | 0.48912193 |
108 | CDK11A | 0.48046862 |
109 | FGR | 0.47902137 |
110 | PRKAA1 | 0.47266474 |
111 | MAP3K9 | 0.47022647 |
112 | CDK3 | 0.45805588 |
113 | GSK3A | 0.45728349 |
114 | DYRK3 | 0.45684396 |
115 | SGK1 | 0.44807644 |
116 | SGK3 | 0.44500912 |
117 | MAP2K6 | 0.44436464 |
118 | RPS6KA3 | 0.44166866 |
119 | FYN | 0.44005327 |
120 | ROCK1 | 0.43803723 |
121 | PDPK1 | 0.43734634 |
122 | MAPK10 | 0.42869411 |
123 | PRKACA | 0.40607752 |
124 | CSNK1E | 0.40575265 |
125 | FES | 0.40315367 |
126 | ITK | 0.39952610 |
127 | CAMK1D | 0.39786189 |
128 | KSR1 | 0.38782103 |
129 | TRIM28 | 0.38645259 |
130 | ERBB4 | 0.38642926 |
131 | PRKCG | 0.38481478 |
132 | BRAF | 0.38298409 |
133 | PRKACB | 0.34554788 |
134 | PDGFRB | 0.34284339 |
135 | MAP2K2 | 0.33448521 |
136 | PRKCA | 0.33123802 |
137 | ERBB2 | 0.31766157 |
138 | FER | 0.30179271 |
139 | PRKCB | 0.29653421 |
140 | GSK3B | 0.29417920 |
141 | STK38 | 0.28955337 |
142 | ZAK | 0.28054508 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 5.04673674 |
2 | Protein export_Homo sapiens_hsa03060 | 3.78428034 |
3 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 3.13691025 |
4 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.59804529 |
5 | Insulin secretion_Homo sapiens_hsa04911 | 2.48858784 |
6 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.30531358 |
7 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.21826165 |
8 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.19598372 |
9 | GABAergic synapse_Homo sapiens_hsa04727 | 2.16763039 |
10 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.06015493 |
11 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.81241264 |
12 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.78844630 |
13 | Morphine addiction_Homo sapiens_hsa05032 | 1.76599532 |
14 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.74759008 |
15 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.72129719 |
16 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.71014262 |
17 | Cocaine addiction_Homo sapiens_hsa05030 | 1.65076050 |
18 | Circadian entrainment_Homo sapiens_hsa04713 | 1.61117985 |
19 | Nicotine addiction_Homo sapiens_hsa05033 | 1.56630110 |
20 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.52473634 |
21 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.51295587 |
22 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.46243886 |
23 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.44319910 |
24 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.41968542 |
25 | Taste transduction_Homo sapiens_hsa04742 | 1.40133331 |
26 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.38024022 |
27 | Long-term depression_Homo sapiens_hsa04730 | 1.31961555 |
28 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.30155822 |
29 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.29428882 |
30 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.25505059 |
31 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.24930410 |
32 | Axon guidance_Homo sapiens_hsa04360 | 1.21387267 |
33 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.18261927 |
34 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.16690702 |
35 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.13318005 |
36 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.13200898 |
37 | Lysosome_Homo sapiens_hsa04142 | 1.11382665 |
38 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.08397965 |
39 | Parkinsons disease_Homo sapiens_hsa05012 | 1.05603597 |
40 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.03462761 |
41 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.03316464 |
42 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.01211813 |
43 | Circadian rhythm_Homo sapiens_hsa04710 | 0.98532725 |
44 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.97443188 |
45 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.94530720 |
46 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.93738166 |
47 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.90493922 |
48 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.90037862 |
49 | Peroxisome_Homo sapiens_hsa04146 | 0.89299825 |
50 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.88410920 |
51 | Long-term potentiation_Homo sapiens_hsa04720 | 0.87548169 |
52 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.86567181 |
53 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.86145087 |
54 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.85476841 |
55 | Renin secretion_Homo sapiens_hsa04924 | 0.85402896 |
56 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.83772809 |
57 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.83433975 |
58 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.82173141 |
59 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.79797218 |
60 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.79398914 |
61 | Salivary secretion_Homo sapiens_hsa04970 | 0.79169590 |
62 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.75999664 |
63 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.75147602 |
64 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.74946146 |
65 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.74720262 |
66 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.73691544 |
67 | Phototransduction_Homo sapiens_hsa04744 | 0.72749970 |
68 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.72578196 |
69 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.72444558 |
70 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.70410327 |
71 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.69372961 |
72 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.68766864 |
73 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.68434062 |
74 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.67858965 |
75 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.67153051 |
76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.66305188 |
77 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.63852197 |
78 | Histidine metabolism_Homo sapiens_hsa00340 | 0.63374642 |
79 | Mineral absorption_Homo sapiens_hsa04978 | 0.62381067 |
80 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.60409557 |
81 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.59984901 |
82 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.59796500 |
83 | Alcoholism_Homo sapiens_hsa05034 | 0.58900526 |
84 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.58899382 |
85 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.58341036 |
86 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.57993847 |
87 | ABC transporters_Homo sapiens_hsa02010 | 0.56881269 |
88 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.56802330 |
89 | Huntingtons disease_Homo sapiens_hsa05016 | 0.55404991 |
90 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.55042893 |
91 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.54423185 |
92 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.54225729 |
93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.54052443 |
94 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.53992045 |
95 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.53484207 |
96 | Gap junction_Homo sapiens_hsa04540 | 0.53192431 |
97 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.51516437 |
98 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.50848403 |
99 | Endocytosis_Homo sapiens_hsa04144 | 0.50419374 |
100 | Alzheimers disease_Homo sapiens_hsa05010 | 0.50402489 |
101 | Bile secretion_Homo sapiens_hsa04976 | 0.48524189 |
102 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.48521049 |
103 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.47821302 |
104 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.47681905 |
105 | Prion diseases_Homo sapiens_hsa05020 | 0.46715761 |
106 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.45314699 |
107 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.45255920 |
108 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.45125405 |
109 | Phagosome_Homo sapiens_hsa04145 | 0.43777775 |
110 | Other glycan degradation_Homo sapiens_hsa00511 | 0.43077306 |
111 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.42790991 |
112 | Tight junction_Homo sapiens_hsa04530 | 0.42228925 |
113 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.42176872 |
114 | Olfactory transduction_Homo sapiens_hsa04740 | 0.40925305 |
115 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.40634400 |
116 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.39207694 |
117 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.37403810 |
118 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37339083 |
119 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36324570 |
120 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.32930580 |
121 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.32487965 |
122 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.31419549 |
123 | Basal transcription factors_Homo sapiens_hsa03022 | 0.31255071 |
124 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.31021787 |