ST8SIA2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)9.18849299
2nucleobase catabolic process (GO:0046113)7.00464411
3response to pheromone (GO:0019236)6.19920103
4central nervous system projection neuron axonogenesis (GO:0021952)5.79255564
5cell migration in hindbrain (GO:0021535)5.75061155
6presynaptic membrane assembly (GO:0097105)5.24734702
7presynaptic membrane organization (GO:0097090)5.02533913
8layer formation in cerebral cortex (GO:0021819)5.00991098
9axonal fasciculation (GO:0007413)4.95339608
10neuron recognition (GO:0008038)4.75264380
11neuron cell-cell adhesion (GO:0007158)4.67793021
12cerebral cortex radially oriented cell migration (GO:0021799)4.57892294
13dendrite morphogenesis (GO:0048813)4.51497099
14regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.49898324
15axon extension (GO:0048675)4.45374688
16central nervous system neuron axonogenesis (GO:0021955)4.29521502
17negative regulation of microtubule polymerization (GO:0031115)4.21352112
18dendritic spine morphogenesis (GO:0060997)4.20101663
19synaptic vesicle endocytosis (GO:0048488)4.14474313
20spinal cord development (GO:0021510)3.85903688
21neuron projection extension (GO:1990138)3.83494802
22limb bud formation (GO:0060174)3.83021734
23olfactory bulb development (GO:0021772)3.81005661
24vocalization behavior (GO:0071625)3.72483535
25postsynaptic membrane organization (GO:0001941)3.68320342
26cerebellum development (GO:0021549)3.66521703
27negative regulation of axon guidance (GO:1902668)3.64584187
28neurotransmitter-gated ion channel clustering (GO:0072578)3.59688035
29regulation of glutamate receptor signaling pathway (GO:1900449)3.57894985
30positive regulation of synapse maturation (GO:0090129)3.57282497
31regulation of synapse structural plasticity (GO:0051823)3.56615747
32glial cell proliferation (GO:0014009)3.54751375
33hippocampus development (GO:0021766)3.49316010
34transmission of nerve impulse (GO:0019226)3.45284089
35neuron migration (GO:0001764)3.45259504
36RNA localization (GO:0006403)3.42693707
37negative regulation of axon extension involved in axon guidance (GO:0048843)3.41633418
38protein localization to synapse (GO:0035418)3.40614004
39mitochondrion transport along microtubule (GO:0047497)3.40450321
40establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.40450321
41positive regulation of dendritic spine morphogenesis (GO:0061003)3.39455662
42ganglion development (GO:0061548)3.38638228
43auditory behavior (GO:0031223)3.33152558
44gamma-aminobutyric acid transport (GO:0015812)3.28913668
45regulation of short-term neuronal synaptic plasticity (GO:0048172)3.28806159
46negative regulation of axon extension (GO:0030517)3.28503808
47establishment of mitochondrion localization (GO:0051654)3.24853812
48cranial nerve morphogenesis (GO:0021602)3.24468668
49regulation of axon extension (GO:0030516)3.24082545
50regulation of synapse maturation (GO:0090128)3.24065521
51regulation of development, heterochronic (GO:0040034)3.22389424
52nonmotile primary cilium assembly (GO:0035058)3.19213023
53regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.18281195
54dendrite development (GO:0016358)3.15213173
55positive regulation of axon extension (GO:0045773)3.12127956
56protein polyglutamylation (GO:0018095)3.11668687
57regulation of microtubule polymerization (GO:0031113)3.11396148
58regulation of axon guidance (GO:1902667)3.08491263
59regulation of NFAT protein import into nucleus (GO:0051532)3.07820611
60positive regulation of synapse assembly (GO:0051965)3.04944505
61cytoplasmic mRNA processing body assembly (GO:0033962)3.04227776
62cerebral cortex neuron differentiation (GO:0021895)3.03010971
63forebrain neuron differentiation (GO:0021879)3.02561943
64glutamate receptor signaling pathway (GO:0007215)3.01930884
65somite development (GO:0061053)3.01445264
66regulation of extent of cell growth (GO:0061387)2.99007203
67cerebral cortex cell migration (GO:0021795)2.98872678
68positive regulation of filopodium assembly (GO:0051491)2.97912553
69sequestering of actin monomers (GO:0042989)2.95997223
70startle response (GO:0001964)2.95510112
71generation of neurons (GO:0048699)2.94188737
72substrate-independent telencephalic tangential migration (GO:0021826)2.93958500
73substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.93958500
74mechanosensory behavior (GO:0007638)2.92813710
75developmental cell growth (GO:0048588)2.92011922
76exploration behavior (GO:0035640)2.91618239
77synapse organization (GO:0050808)2.89761600
78head development (GO:0060322)2.89669599
79neuronal ion channel clustering (GO:0045161)2.88076741
80positive regulation of microtubule polymerization or depolymerization (GO:0031112)2.87731298
81regulation of axon extension involved in axon guidance (GO:0048841)2.87241745
82neuromuscular synaptic transmission (GO:0007274)2.86796002
83regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.86539584
84hindbrain development (GO:0030902)2.86293928
85negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.86111074
86ionotropic glutamate receptor signaling pathway (GO:0035235)2.85746142
87regulation of respiratory system process (GO:0044065)2.84654663
88positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.83457092
89adult walking behavior (GO:0007628)2.82790130
90negative regulation of axonogenesis (GO:0050771)2.82042850
91G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.81915418
92calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.81433132
93regulation of synapse assembly (GO:0051963)2.80543770
94negative regulation of synaptic transmission, GABAergic (GO:0032229)2.80214625
95regulation of timing of cell differentiation (GO:0048505)2.78329077
96synapse assembly (GO:0007416)2.78150745
97establishment of nucleus localization (GO:0040023)2.77823311
98positive regulation of mitochondrial fission (GO:0090141)2.76885257
99negative regulation of catenin import into nucleus (GO:0035414)2.76553563
100proline transport (GO:0015824)2.76389056
101regulation of synapse organization (GO:0050807)2.75975380
102neural tube formation (GO:0001841)2.75924246
103heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.75680897
104positive regulation of protein depolymerization (GO:1901881)2.74853404
105cerebellar Purkinje cell layer development (GO:0021680)2.71774677
106neuron-neuron synaptic transmission (GO:0007270)2.71239744
107synaptic transmission, cholinergic (GO:0007271)2.70803293
108ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.70668942
109lateral sprouting from an epithelium (GO:0060601)2.70009321
110response to auditory stimulus (GO:0010996)2.68861520
111behavioral response to nicotine (GO:0035095)2.68295313
112axonogenesis (GO:0007409)2.68186806
113sympathetic nervous system development (GO:0048485)2.66801273
114neurofilament cytoskeleton organization (GO:0060052)2.66160872
115negative regulation of oligodendrocyte differentiation (GO:0048715)2.65464576
116epithelial cell differentiation involved in kidney development (GO:0035850)2.65122926
117neuron projection extension involved in neuron projection guidance (GO:1902284)2.64858282
118axon extension involved in axon guidance (GO:0048846)2.64858282
119regulation of dendritic spine morphogenesis (GO:0061001)2.64277325
120positive regulation of dendritic spine development (GO:0060999)2.64187446
121retinal ganglion cell axon guidance (GO:0031290)2.64142939
122synaptic vesicle maturation (GO:0016188)2.63254589
123neuron fate determination (GO:0048664)2.62589310
124facial nerve structural organization (GO:0021612)2.62510268
125regulation of collateral sprouting (GO:0048670)2.62484586
126regulation of cAMP-dependent protein kinase activity (GO:2000479)2.61107623
127cell proliferation in forebrain (GO:0021846)2.59423792
128homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.58846176
129proximal/distal pattern formation (GO:0009954)2.58823290
130locomotory exploration behavior (GO:0035641)2.58556883
131synaptic transmission, glutamatergic (GO:0035249)2.58132697
132neuron projection morphogenesis (GO:0048812)2.57915820
133cerebellar granule cell differentiation (GO:0021707)2.57724878
134organelle transport along microtubule (GO:0072384)2.56257332
135positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.56155640
136stress granule assembly (GO:0034063)2.55870458
137intraciliary transport (GO:0042073)2.55799565
138epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.55419541
139neuronal stem cell maintenance (GO:0097150)2.53647006

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.49569337
2* EZH2_27304074_Chip-Seq_ESCs_Mouse2.98399306
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.98097050
4CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.82000071
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.68096236
6NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.62130754
7* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.54898772
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.46355309
9* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.46355309
10GBX2_23144817_ChIP-Seq_PC3_Human2.45702079
11* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.42082685
12EZH2_27294783_Chip-Seq_ESCs_Mouse2.37698401
13RNF2_27304074_Chip-Seq_ESCs_Mouse2.35293190
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.31537805
15TAF15_26573619_Chip-Seq_HEK293_Human2.27773511
16CBX2_27304074_Chip-Seq_ESCs_Mouse2.27468924
17* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26598431
18EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.24752058
19REST_21632747_ChIP-Seq_MESCs_Mouse2.23060541
20* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.19909301
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.19834656
22* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.18446825
23* EED_16625203_ChIP-ChIP_MESCs_Mouse2.10293652
24* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.04983469
25RNF2_27304074_Chip-Seq_NSC_Mouse2.04628468
26RING1B_27294783_Chip-Seq_NPCs_Mouse1.99658130
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.93520729
28TP63_19390658_ChIP-ChIP_HaCaT_Human1.93374120
29SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.92425096
30* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.91763722
31ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.91582076
32ERG_21242973_ChIP-ChIP_JURKAT_Human1.91568636
33IGF1R_20145208_ChIP-Seq_DFB_Human1.90793968
34ZFP281_18757296_ChIP-ChIP_E14_Mouse1.88671525
35TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.86549576
36* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.82798529
37* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.81828883
38FUS_26573619_Chip-Seq_HEK293_Human1.81220436
39REST_18959480_ChIP-ChIP_MESCs_Mouse1.80429300
40* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.78109660
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.77485204
42EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.72135464
43CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.71327960
44TP53_20018659_ChIP-ChIP_R1E_Mouse1.67795162
45* RING1B_27294783_Chip-Seq_ESCs_Mouse1.66732069
46GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.63373036
47RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.62222332
48TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.61919022
49POU5F1_16153702_ChIP-ChIP_HESCs_Human1.58734439
50SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.58344859
51VDR_22108803_ChIP-Seq_LS180_Human1.57975484
52AR_21572438_ChIP-Seq_LNCaP_Human1.57418820
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56164278
54SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.54824676
55* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.52990948
56* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.52676917
57CTBP2_25329375_ChIP-Seq_LNCAP_Human1.51297162
58EWS_26573619_Chip-Seq_HEK293_Human1.50516734
59ZFP281_27345836_Chip-Seq_ESCs_Mouse1.48158945
60SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47790143
61SALL1_21062744_ChIP-ChIP_HESCs_Human1.45682455
62DROSHA_22980978_ChIP-Seq_HELA_Human1.42263154
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36881228
64POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.36881228
65KDM2B_26808549_Chip-Seq_K562_Human1.36098905
66RARB_27405468_Chip-Seq_BRAIN_Mouse1.35578616
67MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.34959188
68ZNF274_21170338_ChIP-Seq_K562_Hela1.31778254
69AHR_22903824_ChIP-Seq_MCF-7_Human1.31462691
70PIAS1_25552417_ChIP-Seq_VCAP_Human1.31340329
71ARNT_22903824_ChIP-Seq_MCF-7_Human1.30729285
72RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.30600586
73NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.29967181
74TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.27566884
75MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25733600
76MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24436064
77IRF1_19129219_ChIP-ChIP_H3396_Human1.22235434
78ZFP57_27257070_Chip-Seq_ESCs_Mouse1.22162494
79CTBP1_25329375_ChIP-Seq_LNCAP_Human1.20661316
80AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.19477877
81STAT3_23295773_ChIP-Seq_U87_Human1.16860858
82AR_25329375_ChIP-Seq_VCAP_Human1.16840448
83IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16206033
84CBP_20019798_ChIP-Seq_JUKART_Human1.16206033
85HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.15318606
86YAP1_20516196_ChIP-Seq_MESCs_Mouse1.15268709
87CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14963132
88* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.14572970
89UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.13879371
90SOX2_21211035_ChIP-Seq_LN229_Gbm1.12325249
91AR_19668381_ChIP-Seq_PC3_Human1.12143712
92ISL1_27105846_Chip-Seq_CPCs_Mouse1.10959464
93* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.10152852
94SOX9_26525672_Chip-Seq_HEART_Mouse1.09673559
95* RUNX2_22187159_ChIP-Seq_PCA_Human1.08496013
96FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.07609873
97* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06926907
98* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.06441607
99NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04846215
100* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04685561
101TOP2B_26459242_ChIP-Seq_MCF-7_Human1.04305487
102TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03380106
103IKZF1_21737484_ChIP-ChIP_HCT116_Human1.00665019
104POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.99753113
105TCF4_23295773_ChIP-Seq_U87_Human0.99632280
106HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.99365128
107ELK4_26923725_Chip-Seq_MESODERM_Mouse0.98610005
108P53_22127205_ChIP-Seq_FIBROBLAST_Human0.98493742
109NANOG_18555785_Chip-Seq_ESCs_Mouse0.97900891
110TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97614598
111GATA1_26923725_Chip-Seq_HPCs_Mouse0.97555618
112GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96893861
113DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.96679741
114* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96675830
115P300_19829295_ChIP-Seq_ESCs_Human0.94980394
116TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.93914553
117ER_23166858_ChIP-Seq_MCF-7_Human0.93764788
118* SMAD4_21741376_ChIP-Seq_HESCs_Human0.93256205
119STAT6_21828071_ChIP-Seq_BEAS2B_Human0.93007742
120STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.92743704
121POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.92653648
122TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.92143964
123SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92093054
124SOX2_16153702_ChIP-ChIP_HESCs_Human0.91754651
125KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.91348881
126SMAD4_21799915_ChIP-Seq_A2780_Human0.91181382
127TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.89569015
128SMAD3_21741376_ChIP-Seq_EPCs_Human0.89199392
129SOX3_22085726_ChIP-Seq_NPCs_Mouse0.89083157
130MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.88711632
131TBX3_20139965_ChIP-Seq_ESCs_Mouse0.88451585

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0000778_abnormal_nervous_system3.55575237
2MP0004859_abnormal_synaptic_plasticity3.44060795
3MP0006292_abnormal_olfactory_placode2.77959283
4MP0003122_maternal_imprinting2.64948439
5MP0004270_analgesia2.58951501
6MP0006276_abnormal_autonomic_nervous2.54888844
7MP0008789_abnormal_olfactory_epithelium2.51904810
8MP0005499_abnormal_olfactory_system2.46217986
9MP0005394_taste/olfaction_phenotype2.46217986
10MP0005423_abnormal_somatic_nervous2.41010435
11MP0002184_abnormal_innervation2.30985230
12MP0003890_abnormal_embryonic-extraembry2.20436438
13MP0003635_abnormal_synaptic_transmissio2.20318589
14MP0002822_catalepsy2.16988433
15MP0003880_abnormal_central_pattern2.16412051
16* MP0002063_abnormal_learning/memory/cond2.16122031
17MP0010030_abnormal_orbit_morphology2.15649634
18MP0000569_abnormal_digit_pigmentation2.13470353
19MP0002102_abnormal_ear_morphology2.09607977
20MP0003121_genomic_imprinting1.95321231
21MP0000537_abnormal_urethra_morphology1.92856145
22MP0002653_abnormal_ependyma_morphology1.89424439
23MP0000631_abnormal_neuroendocrine_gland1.82741493
24MP0004858_abnormal_nervous_system1.78856733
25MP0003938_abnormal_ear_development1.78708787
26* MP0003861_abnormal_nervous_system1.76765620
27MP0002736_abnormal_nociception_after1.74301383
28MP0002734_abnormal_mechanical_nocicepti1.73948320
29MP0002557_abnormal_social/conspecific_i1.67517200
30MP0003385_abnormal_body_wall1.67301314
31MP0000049_abnormal_middle_ear1.67168165
32MP0000955_abnormal_spinal_cord1.65662839
33* MP0002572_abnormal_emotion/affect_behav1.62160031
34MP0004142_abnormal_muscle_tone1.61945324
35MP0003119_abnormal_digestive_system1.60981201
36MP0002272_abnormal_nervous_system1.60960757
37MP0002751_abnormal_autonomic_nervous1.59454851
38MP0002249_abnormal_larynx_morphology1.57875394
39MP0003942_abnormal_urinary_system1.56559019
40MP0002938_white_spotting1.55765068
41* MP0004811_abnormal_neuron_physiology1.54804883
42MP0002234_abnormal_pharynx_morphology1.53876670
43MP0003787_abnormal_imprinting1.53829058
44MP0002733_abnormal_thermal_nociception1.51813894
45MP0005248_abnormal_Harderian_gland1.49043728
46* MP0002152_abnormal_brain_morphology1.46611709
47MP0003755_abnormal_palate_morphology1.44573745
48MP0001486_abnormal_startle_reflex1.40792455
49MP0005645_abnormal_hypothalamus_physiol1.35962512
50MP0004885_abnormal_endolymph1.34306832
51* MP0002882_abnormal_neuron_morphology1.33175159
52MP0002735_abnormal_chemical_nociception1.32862340
53MP0002116_abnormal_craniofacial_bone1.32842365
54MP0002233_abnormal_nose_morphology1.31613443
55MP0000516_abnormal_urinary_system1.30688534
56MP0005367_renal/urinary_system_phenotyp1.30688534
57MP0000566_synostosis1.28783282
58MP0003315_abnormal_perineum_morphology1.28521484
59MP0005386_behavior/neurological_phenoty1.26015823
60MP0004924_abnormal_behavior1.26015823
61MP0000534_abnormal_ureter_morphology1.24617031
62MP0001440_abnormal_grooming_behavior1.22539205
63MP0004133_heterotaxia1.22308785
64MP0001970_abnormal_pain_threshold1.19147221
65MP0005187_abnormal_penis_morphology1.18990895
66MP0002081_perinatal_lethality1.17453896
67MP0009745_abnormal_behavioral_response1.17325840
68MP0001984_abnormal_olfaction1.16262755
69MP0002932_abnormal_joint_morphology1.15088179
70MP0002064_seizures1.14700551
71MP0002638_abnormal_pupillary_reflex1.13920629
72MP0003935_abnormal_craniofacial_develop1.12839932
73MP0008877_abnormal_DNA_methylation1.12012916
74MP0001968_abnormal_touch/_nociception1.11845476
75MP0001529_abnormal_vocalization1.10990651
76MP0002752_abnormal_somatic_nervous1.10507348
77MP0006072_abnormal_retinal_apoptosis1.09445913
78MP0005551_abnormal_eye_electrophysiolog1.09016528
79MP0009250_abnormal_appendicular_skeleto1.08685860
80MP0005253_abnormal_eye_physiology1.07284720
81MP0003137_abnormal_impulse_conducting1.06091924
82MP0002282_abnormal_trachea_morphology1.05772003
83MP0000026_abnormal_inner_ear1.05443778
84MP0001293_anophthalmia1.05350632
85MP0002067_abnormal_sensory_capabilities1.02824937
86MP0003283_abnormal_digestive_organ1.01214676
87MP0000538_abnormal_urinary_bladder1.00439371
88MP0002177_abnormal_outer_ear0.97395824
89MP0001299_abnormal_eye_distance/0.97182636
90MP0005257_abnormal_intraocular_pressure0.96192259
91MP0002069_abnormal_eating/drinking_beha0.94799918
92MP0001188_hyperpigmentation0.94731145
93MP0005195_abnormal_posterior_eye0.94544545
94MP0004145_abnormal_muscle_electrophysio0.92943780
95* MP0002066_abnormal_motor_capabilities/c0.92607453
96MP0003937_abnormal_limbs/digits/tail_de0.92513705
97MP0009046_muscle_twitch0.91928513
98MP0009053_abnormal_anal_canal0.91900000
99MP0001286_abnormal_eye_development0.91121418
100MP0009780_abnormal_chondrocyte_physiolo0.90452479
101MP0001502_abnormal_circadian_rhythm0.90083226
102MP0002114_abnormal_axial_skeleton0.88008230
103MP0001905_abnormal_dopamine_level0.87421164
104MP0003115_abnormal_respiratory_system0.86556829
105MP0000428_abnormal_craniofacial_morphol0.84709837
106MP0001986_abnormal_taste_sensitivity0.83750263
107MP0001177_atelectasis0.81815841
108MP0008995_early_reproductive_senescence0.80467395
109MP0005646_abnormal_pituitary_gland0.80431822
110MP0002092_abnormal_eye_morphology0.80191244
111MP0004742_abnormal_vestibular_system0.79585492
112MP0001943_abnormal_respiration0.78702323
113MP0001963_abnormal_hearing_physiology0.77381699
114MP0003567_abnormal_fetal_cardiomyocyte0.73814140
115MP0000678_abnormal_parathyroid_gland0.73757804
116MP0001348_abnormal_lacrimal_gland0.73279436
117MP0003123_paternal_imprinting0.72155817
118MP0001485_abnormal_pinna_reflex0.70192218
119MP0005391_vision/eye_phenotype0.70045960
120MP0002909_abnormal_adrenal_gland0.69644007
121MP0002697_abnormal_eye_size0.68096567

Predicted human phenotypes

RankGene SetZ-score
1Hepatoblastoma (HP:0002884)4.08237943
2Amyotrophic lateral sclerosis (HP:0007354)3.70215504
3Drooling (HP:0002307)3.19505901
4Excessive salivation (HP:0003781)3.19505901
5Hypoplasia of the brainstem (HP:0002365)3.02613568
6Aplasia/Hypoplasia of the brainstem (HP:0007362)3.02613568
7Gait imbalance (HP:0002141)3.02208906
8Cortical dysplasia (HP:0002539)2.98286090
9Tented upper lip vermilion (HP:0010804)2.90692148
10Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.86115537
11Short 4th metacarpal (HP:0010044)2.86115537
12Lissencephaly (HP:0001339)2.85226988
13Polyphagia (HP:0002591)2.82508235
14Renal duplication (HP:0000075)2.81657197
15Retinal dysplasia (HP:0007973)2.79104476
16True hermaphroditism (HP:0010459)2.77352198
17Focal motor seizures (HP:0011153)2.75684564
18Pachygyria (HP:0001302)2.75357575
19Astrocytoma (HP:0009592)2.74085807
20Abnormality of the astrocytes (HP:0100707)2.74085807
21Pancreatic fibrosis (HP:0100732)2.72687909
22Exotropia (HP:0000577)2.70809889
23Limb dystonia (HP:0002451)2.70669804
24Akinesia (HP:0002304)2.70131783
25Abnormality of midbrain morphology (HP:0002418)2.67435757
26Molar tooth sign on MRI (HP:0002419)2.67435757
27Pancreatic cysts (HP:0001737)2.62196929
28Supranuclear gaze palsy (HP:0000605)2.59953492
29Nephronophthisis (HP:0000090)2.58604303
30High anterior hairline (HP:0009890)2.57807601
31Failure to thrive in infancy (HP:0001531)2.55630784
32Medial flaring of the eyebrow (HP:0010747)2.48682260
33Bilateral microphthalmos (HP:0007633)2.47805150
34Oligodactyly (hands) (HP:0001180)2.42150968
35Congenital primary aphakia (HP:0007707)2.40991876
36Agitation (HP:0000713)2.39574802
37Genital tract atresia (HP:0001827)2.37892608
38Shoulder girdle muscle weakness (HP:0003547)2.36995508
39Fetal akinesia sequence (HP:0001989)2.36125042
40Vaginal atresia (HP:0000148)2.34810812
41Abnormality of the lower motor neuron (HP:0002366)2.33926950
42Sleep apnea (HP:0010535)2.33261769
43Hypsarrhythmia (HP:0002521)2.32418396
44Abnormality of the intervertebral disk (HP:0005108)2.31878342
45Poor eye contact (HP:0000817)2.30551849
46Nephrogenic diabetes insipidus (HP:0009806)2.30426230
47Abnormality of the labia minora (HP:0012880)2.30406049
48Hyperventilation (HP:0002883)2.30312739
49Volvulus (HP:0002580)2.29769165
50Broad-based gait (HP:0002136)2.29239007
51Obstructive sleep apnea (HP:0002870)2.28090445
52Renal hypoplasia (HP:0000089)2.24384585
53Facial hemangioma (HP:0000329)2.22879405
54Ependymoma (HP:0002888)2.22753427
55Abnormality of the corticospinal tract (HP:0002492)2.20867944
56Coronal craniosynostosis (HP:0004440)2.19986822
57EEG with generalized epileptiform discharges (HP:0011198)2.19689773
58Amblyopia (HP:0000646)2.19521605
59Elfin facies (HP:0004428)2.19490039
60Atrophy/Degeneration involving motor neurons (HP:0007373)2.18993585
61Optic nerve hypoplasia (HP:0000609)2.18314320
62Shawl scrotum (HP:0000049)2.16525604
63Epileptiform EEG discharges (HP:0011182)2.16457581
64Wrist flexion contracture (HP:0001239)2.15637305
65Abnormality of the 4th metacarpal (HP:0010012)2.14381936
66Open mouth (HP:0000194)2.13851693
67Sacral dimple (HP:0000960)2.13061837
68Heterotopia (HP:0002282)2.11637731
69Abnormality of the renal medulla (HP:0100957)2.10199297
70Protruding tongue (HP:0010808)2.10180880
71Short philtrum (HP:0000322)2.10169404
72Myokymia (HP:0002411)2.09541324
73Hyperacusis (HP:0010780)2.08810879
74Mutism (HP:0002300)2.08368151
75Esotropia (HP:0000565)2.06866157
76Hemiparesis (HP:0001269)2.06674241
77Intestinal atresia (HP:0011100)2.05603654
78Broad alveolar ridges (HP:0000187)2.04740012
79Thyroid-stimulating hormone excess (HP:0002925)2.04453464
80Urinary urgency (HP:0000012)2.03858376
81Febrile seizures (HP:0002373)2.03569837
82Anophthalmia (HP:0000528)2.02958726
83Anencephaly (HP:0002323)2.02046047
84Midline defect of the nose (HP:0004122)2.00925478
85Postaxial hand polydactyly (HP:0001162)2.00279196
86Spastic tetraplegia (HP:0002510)2.00091477
87Vitreoretinal degeneration (HP:0000655)1.99606764
88Epileptic encephalopathy (HP:0200134)1.99393988
89Chronic hepatic failure (HP:0100626)1.97090171
90Aplasia/Hypoplasia of the sternum (HP:0006714)1.96149228
91Abnormal eating behavior (HP:0100738)1.95550754
92Ankle clonus (HP:0011448)1.94422994
93Abnormality of salivation (HP:0100755)1.94383482
94Oligodactyly (HP:0012165)1.93156545
95Bifid tongue (HP:0010297)1.92125847
96Spina bifida occulta (HP:0003298)1.91831506
97Scrotal hypoplasia (HP:0000046)1.89181419
98Impaired social interactions (HP:0000735)1.89164988
99Abnormal social behavior (HP:0012433)1.89164988
100Pendular nystagmus (HP:0012043)1.88851991
101Glioma (HP:0009733)1.88366098
102Type II lissencephaly (HP:0007260)1.87389774
103Overriding aorta (HP:0002623)1.86863826
104Renovascular hypertension (HP:0100817)1.86585861
105Autism (HP:0000717)1.85941944
106Insomnia (HP:0100785)1.85931092
107Inappropriate behavior (HP:0000719)1.85847021
108Hypoplasia of the corpus callosum (HP:0002079)1.85548681
109Neoplasm of the heart (HP:0100544)1.85146673
110Rib fusion (HP:0000902)1.84528277
111Cutaneous finger syndactyly (HP:0010554)1.82330912
112Abnormality of the pubic bones (HP:0003172)1.81539174
113Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.80589755
114Lymphangioma (HP:0100764)1.80481056
115Patellar aplasia (HP:0006443)1.80306750
116Aplasia of the musculature (HP:0100854)1.80243052
117Postaxial foot polydactyly (HP:0001830)1.78145408
118Spastic gait (HP:0002064)1.77818729
119Specific learning disability (HP:0001328)1.77571606
120Poor suck (HP:0002033)1.77422405
121Shallow orbits (HP:0000586)1.77168996
122Preaxial hand polydactyly (HP:0001177)1.76434824
123Broad foot (HP:0001769)1.76247015
124Choanal stenosis (HP:0000452)1.76160802
125Inability to walk (HP:0002540)1.75620862
126Long clavicles (HP:0000890)1.75410700
127Genetic anticipation (HP:0003743)1.74006866
128Labial hypoplasia (HP:0000066)1.73791985
129Intellectual disability, severe (HP:0010864)1.73252410
130Sclerocornea (HP:0000647)1.73073895
131Megalocornea (HP:0000485)1.72834173
132Gastroesophageal reflux (HP:0002020)1.72741410
133Morphological abnormality of the pyramidal tract (HP:0002062)1.72384896
134Atonic seizures (HP:0010819)1.71158934
135Cystic liver disease (HP:0006706)1.70816544
136Septo-optic dysplasia (HP:0100842)1.70225970
137Morphological abnormality of the middle ear (HP:0008609)1.70057846
138Absent speech (HP:0001344)1.69987861
139Aplasia/Hypoplasia of the tongue (HP:0010295)1.69811433
140Patellar dislocation (HP:0002999)1.69611276
141Poor coordination (HP:0002370)1.69455833
142Long nose (HP:0003189)1.69119198
143Thin upper lip vermilion (HP:0000219)1.68708752
144Focal seizures (HP:0007359)1.68611251
145Obsessive-compulsive behavior (HP:0000722)1.68139390
146Progressive cerebellar ataxia (HP:0002073)1.67457485
147Abnormality of the aortic arch (HP:0012303)1.66498788
148Narrow forehead (HP:0000341)1.65957506
149Polymicrogyria (HP:0002126)1.63530326
150Embryonal neoplasm (HP:0002898)1.63441783
151Micropenis (HP:0000054)1.61836884
152Narrow nasal bridge (HP:0000446)1.61561379
153Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.61508995
154Intellectual disability, moderate (HP:0002342)1.61112241
155Atelectasis (HP:0100750)1.60169905
156Aqueductal stenosis (HP:0002410)1.60159756

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK17.79523009
2DYRK23.61251981
3WNK33.36667272
4EPHB23.01222319
5NTRK22.78453522
6MAPK132.48347056
7ERBB32.31702869
8UHMK12.13081334
9TYRO31.97338085
10PHKG11.92190515
11PHKG21.92190515
12ICK1.91863594
13LATS21.89249095
14MINK11.85060758
15MAP4K21.81936557
16MAP3K91.76928432
17MAP3K41.70948683
18TRIM281.70618947
19KSR11.68440246
20NTRK31.66574793
21SIK21.65862300
22MAP2K71.45900871
23EPHA31.36511148
24CASK1.33898996
25PAK61.31052187
26DDR21.27727670
27CDK121.18654347
28MARK21.12893245
29CSNK1G21.11772363
30CDK51.07801012
31NTRK11.04046141
32PINK11.02534399
33CDK181.01609132
34FGFR21.01295221
35EPHA41.00787859
36DYRK1A1.00544457
37CSNK1G31.00539868
38GRK50.98269981
39DAPK20.96657718
40CDK150.96030396
41BCR0.95511295
42MAP3K60.92992214
43CSNK1A1L0.92612244
44PDGFRA0.91178147
45SIK30.91068725
46MAP3K100.90294573
47RPS6KA40.89799167
48FRK0.89350516
49CDK140.88828983
50YES10.86440789
51BMPR1B0.85099496
52CDK11A0.83916846
53PKN10.82226892
54RPS6KA20.82060927
55MAP2K40.80975031
56ERBB20.79824571
57LIMK10.79471955
58BRSK10.77841334
59DYRK1B0.77587031
60INSRR0.75550088
61ADRBK20.71029705
62TAOK20.70109518
63PRKCZ0.69990829
64PRKCE0.68745361
65CSNK1G10.67316019
66SGK4940.65323473
67SGK2230.65323473
68PRKCG0.63772149
69MKNK20.60833667
70PAK30.60664739
71DYRK30.57352022
72LATS10.56593624
73PNCK0.56276444
74CAMK40.55515985
75DAPK10.54173409
76MAPK90.53695677
77CDC42BPA0.53273338
78CAMK2B0.52168134
79TNIK0.51165515
80MKNK10.50103706
81AURKA0.50019225
82CHEK20.49627995
83STK38L0.48942466
84BCKDK0.47291692
85CAMK1G0.46934196
86ADRBK10.46628266
87STK110.46403617
88ALK0.45884795
89BRD40.45376350
90ROCK10.45123751
91EIF2AK20.45024803
92CCNB10.43956866
93CSNK1D0.43735294
94MAPK80.43469389
95AKT30.42700764
96MAPK40.42463711
97WNK40.42158273
98PLK20.42034063
99MAPK150.41432100
100PRKAA10.40223982
101PRPF4B0.40042038
102MATK0.39943901
103SGK20.39597849
104RPS6KA10.38501750
105CSNK1E0.38455480
106CDK10.36758670
107CAMK2A0.36260215
108AKT20.36065763
109PRKACA0.35883952
110FGR0.35795504
111FGFR10.35778101
112GSK3B0.35197954
113MAP2K60.33898640
114CDK30.33855144
115PRKD30.33529915
116PRKACB0.33462167
117MUSK0.33289254
118CSNK1A10.31989529
119OXSR10.31569124
120CAMKK20.31521076
121FYN0.31262549
122CDK190.31234441
123TGFBR10.30884723
124CAMK10.30645419
125MAPK120.30011694
126PRKG10.29809378
127MAPK100.29697424
128SRPK10.29037151
129PRKDC0.27941865
130CAMKK10.27792309
131GRK10.27753067
132ZAK0.26466729
133RPS6KA30.24852160

Predicted pathways (KEGG)

RankGene SetZ-score
1Axon guidance_Homo sapiens_hsa043603.26910057
2Nicotine addiction_Homo sapiens_hsa050332.61879874
3Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.47353726
4Basal cell carcinoma_Homo sapiens_hsa052172.34406220
5Hedgehog signaling pathway_Homo sapiens_hsa043402.14719071
6Other types of O-glycan biosynthesis_Homo sapiens_hsa005142.09711608
7Steroid biosynthesis_Homo sapiens_hsa001002.08464277
8Colorectal cancer_Homo sapiens_hsa052101.99808963
9Hippo signaling pathway_Homo sapiens_hsa043901.88539027
10Gap junction_Homo sapiens_hsa045401.82845730
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.81195133
12Endometrial cancer_Homo sapiens_hsa052131.80864856
13Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.80694492
14Glutamatergic synapse_Homo sapiens_hsa047241.77626519
15Dopaminergic synapse_Homo sapiens_hsa047281.77366291
16GABAergic synapse_Homo sapiens_hsa047271.75686878
17Wnt signaling pathway_Homo sapiens_hsa043101.68606205
18Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.66530560
19Cardiac muscle contraction_Homo sapiens_hsa042601.66387707
20Circadian entrainment_Homo sapiens_hsa047131.60652451
21Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.55619008
22Butanoate metabolism_Homo sapiens_hsa006501.51439674
23Cocaine addiction_Homo sapiens_hsa050301.50777129
24Morphine addiction_Homo sapiens_hsa050321.47967321
25Cholinergic synapse_Homo sapiens_hsa047251.46835266
26ErbB signaling pathway_Homo sapiens_hsa040121.45834023
27Serotonergic synapse_Homo sapiens_hsa047261.44190798
28Synaptic vesicle cycle_Homo sapiens_hsa047211.43921990
29Olfactory transduction_Homo sapiens_hsa047401.41933163
30Melanogenesis_Homo sapiens_hsa049161.36667517
31Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.32888250
32Taste transduction_Homo sapiens_hsa047421.31205994
33Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.28520203
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.28497451
35Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.27522537
36mTOR signaling pathway_Homo sapiens_hsa041501.26882978
37Notch signaling pathway_Homo sapiens_hsa043301.26326482
38Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.26194264
39Amphetamine addiction_Homo sapiens_hsa050311.21751989
40Neurotrophin signaling pathway_Homo sapiens_hsa047221.21658774
41Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.21330025
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.21244668
43Long-term potentiation_Homo sapiens_hsa047201.20160772
44Viral myocarditis_Homo sapiens_hsa054161.19970650
45GnRH signaling pathway_Homo sapiens_hsa049121.18523990
46Long-term depression_Homo sapiens_hsa047301.17908477
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.17435116
48Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.17293847
49Parkinsons disease_Homo sapiens_hsa050121.15749945
50Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.15188841
51mRNA surveillance pathway_Homo sapiens_hsa030151.14358603
52Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.14344716
53Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.13625970
54Renal cell carcinoma_Homo sapiens_hsa052111.13338668
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.12490790
56Oocyte meiosis_Homo sapiens_hsa041141.11682231
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.09964738
58Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.09603422
59Oxytocin signaling pathway_Homo sapiens_hsa049211.08524143
60Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.07626705
61Oxidative phosphorylation_Homo sapiens_hsa001901.05041997
62Glioma_Homo sapiens_hsa052141.04058222
63Protein export_Homo sapiens_hsa030601.02647545
64Choline metabolism in cancer_Homo sapiens_hsa052310.99782307
65Longevity regulating pathway - mammal_Homo sapiens_hsa042110.98378136
66MAPK signaling pathway_Homo sapiens_hsa040100.96986496
67Adherens junction_Homo sapiens_hsa045200.96246236
68MicroRNAs in cancer_Homo sapiens_hsa052060.93883057
69Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.93748279
70Estrogen signaling pathway_Homo sapiens_hsa049150.90796324
71Thyroid hormone signaling pathway_Homo sapiens_hsa049190.88560316
72Basal transcription factors_Homo sapiens_hsa030220.88350530
73Aldosterone synthesis and secretion_Homo sapiens_hsa049250.87677857
74Renin secretion_Homo sapiens_hsa049240.87144900
75Rap1 signaling pathway_Homo sapiens_hsa040150.87115392
76Dorso-ventral axis formation_Homo sapiens_hsa043200.86974839
77Insulin secretion_Homo sapiens_hsa049110.84498890
78VEGF signaling pathway_Homo sapiens_hsa043700.81208088
79Tight junction_Homo sapiens_hsa045300.79514720
80Huntingtons disease_Homo sapiens_hsa050160.79298616
81Type II diabetes mellitus_Homo sapiens_hsa049300.77772215
82Regulation of autophagy_Homo sapiens_hsa041400.77194862
83Fanconi anemia pathway_Homo sapiens_hsa034600.76865522
84Alzheimers disease_Homo sapiens_hsa050100.76812000
85Ras signaling pathway_Homo sapiens_hsa040140.76388620
86Dilated cardiomyopathy_Homo sapiens_hsa054140.76373012
87Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.75402708
88Non-small cell lung cancer_Homo sapiens_hsa052230.74914987
89Pathways in cancer_Homo sapiens_hsa052000.74314870
90Phototransduction_Homo sapiens_hsa047440.72944889
91Collecting duct acid secretion_Homo sapiens_hsa049660.72485986
92AMPK signaling pathway_Homo sapiens_hsa041520.72415096
93Ovarian steroidogenesis_Homo sapiens_hsa049130.71564943
94Insulin signaling pathway_Homo sapiens_hsa049100.70605687
95alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.69108319
96cAMP signaling pathway_Homo sapiens_hsa040240.68725274
97Alcoholism_Homo sapiens_hsa050340.68626342
98N-Glycan biosynthesis_Homo sapiens_hsa005100.68167362
99Proteoglycans in cancer_Homo sapiens_hsa052050.67693767
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.67115425
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65764689
102Chronic myeloid leukemia_Homo sapiens_hsa052200.65707357
103Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65507829
104Ether lipid metabolism_Homo sapiens_hsa005650.65201604
105Propanoate metabolism_Homo sapiens_hsa006400.64053914
106Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64037696
107Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63011596
108Gastric acid secretion_Homo sapiens_hsa049710.62450037
109Melanoma_Homo sapiens_hsa052180.61995345
110Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61353190
111Salivary secretion_Homo sapiens_hsa049700.60473294
112Linoleic acid metabolism_Homo sapiens_hsa005910.60443915
113Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60442387
114Pancreatic cancer_Homo sapiens_hsa052120.58919782
115TGF-beta signaling pathway_Homo sapiens_hsa043500.57991592
116Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.57002048
117Calcium signaling pathway_Homo sapiens_hsa040200.55904424
118Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51028819
119Sphingolipid signaling pathway_Homo sapiens_hsa040710.50476969
120Endocytosis_Homo sapiens_hsa041440.49999134
121Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.49337951
122Prion diseases_Homo sapiens_hsa050200.48786563
123Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48350932
124Prolactin signaling pathway_Homo sapiens_hsa049170.47927287
125Circadian rhythm_Homo sapiens_hsa047100.47208854
126Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44976353
127Vibrio cholerae infection_Homo sapiens_hsa051100.41648962
128RNA degradation_Homo sapiens_hsa030180.40252267
129Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.39883997
130Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39066298
131Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.36051272
132RNA polymerase_Homo sapiens_hsa030200.31781707
133beta-Alanine metabolism_Homo sapiens_hsa004100.30334754
134Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28890850
135Nitrogen metabolism_Homo sapiens_hsa009100.27301835

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