STAB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation by symbiont of host defense response (GO:0052509)7.13626546
2modulation by symbiont of host defense response (GO:0052031)7.13626546
3modulation by organism of immune response of other organism involved in symbiotic interaction (GO:007.13626546
4modulation by organism of defense response of other organism involved in symbiotic interaction (GO:07.13626546
5positive regulation by organism of defense response of other organism involved in symbiotic interact7.13626546
6modulation by symbiont of host immune response (GO:0052553)7.13626546
7regulation of interferon-beta biosynthetic process (GO:0045357)6.36541468
8negative regulation of interleukin-12 production (GO:0032695)5.50887755
9macrophage activation involved in immune response (GO:0002281)5.37245049
10positive regulation of interleukin-8 biosynthetic process (GO:0045416)5.16394277
11microglial cell activation (GO:0001774)4.95367191
12regulation of mononuclear cell migration (GO:0071675)4.76553411
13negative regulation of granulocyte differentiation (GO:0030853)4.55838919
14pinocytosis (GO:0006907)4.53469850
15neutrophil activation involved in immune response (GO:0002283)4.48647258
16response to host immune response (GO:0052572)4.48585556
17response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.48585556
18glycosphingolipid catabolic process (GO:0046479)4.36473857
19positive regulation of interferon-alpha production (GO:0032727)4.17564483
20phospholipid homeostasis (GO:0055091)4.15069887
21neutrophil mediated immunity (GO:0002446)4.13109594
22cellular response to thyroid hormone stimulus (GO:0097067)4.12637408
23response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.08525418
24response to host (GO:0075136)4.08525418
25response to host defenses (GO:0052200)4.08525418
26oligosaccharide catabolic process (GO:0009313)3.95623310
27regulation of interferon-alpha production (GO:0032647)3.95100957
28amino sugar catabolic process (GO:0046348)3.95071192
29I-kappaB phosphorylation (GO:0007252)3.94877472
30glycolipid catabolic process (GO:0019377)3.90994199
31negative regulation of cell killing (GO:0031342)3.88181590
32negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.88181590
33N-acetylneuraminate metabolic process (GO:0006054)3.84559942
34apoptotic cell clearance (GO:0043277)3.83381091
35T-helper 1 type immune response (GO:0042088)3.80364381
36macrophage activation (GO:0042116)3.78878288
37regulation of macrophage chemotaxis (GO:0010758)3.78145876
38mannose metabolic process (GO:0006013)3.76356805
39lipopolysaccharide-mediated signaling pathway (GO:0031663)3.76301480
40positive regulation of gamma-delta T cell activation (GO:0046645)3.74913904
41negative regulation of erythrocyte differentiation (GO:0045647)3.73895263
42detection of molecule of bacterial origin (GO:0032490)3.73425169
43antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.73106958
44myeloid cell activation involved in immune response (GO:0002275)3.67977474
45regulation of B cell receptor signaling pathway (GO:0050855)3.66378594
46positive regulation of mast cell activation involved in immune response (GO:0033008)3.65743935
47positive regulation of mast cell degranulation (GO:0043306)3.65743935
48positive regulation of cellular amide metabolic process (GO:0034250)3.61307545
49adenosine receptor signaling pathway (GO:0001973)3.60970364
50regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.59941808
51response to muramyl dipeptide (GO:0032495)3.58119246
52positive regulation of B cell differentiation (GO:0045579)3.57173893
53natural killer cell mediated cytotoxicity (GO:0042267)3.52631201
54natural killer cell mediated immunity (GO:0002228)3.52631201
55regulation of interleukin-8 biosynthetic process (GO:0045414)3.52474294
56hyaluronan catabolic process (GO:0030214)3.49995939
57positive regulation of leukocyte degranulation (GO:0043302)3.49768127
58germinal center formation (GO:0002467)3.48615284
59lipoprotein transport (GO:0042953)3.48393331
60positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.46109856
61positive regulation of antigen processing and presentation (GO:0002579)3.45985620
62ceramide catabolic process (GO:0046514)3.45865886
63macroautophagy (GO:0016236)3.43142032
64positive regulation of chemokine biosynthetic process (GO:0045080)3.42799889
65response to peptidoglycan (GO:0032494)3.38662054
66positive regulation of mast cell activation (GO:0033005)3.38191738
67negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.36950962
68negative regulation of lipid storage (GO:0010888)3.36145709
69negative regulation of cytokine production involved in immune response (GO:0002719)3.35363914
70immunoglobulin mediated immune response (GO:0016064)3.35249697
71regulation of myeloid leukocyte mediated immunity (GO:0002886)3.33211252
72adhesion of symbiont to host cell (GO:0044650)3.32107114
73virion attachment to host cell (GO:0019062)3.32107114
74positive regulation of cholesterol efflux (GO:0010875)3.31290721
75regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.30601297
76NIK/NF-kappaB signaling (GO:0038061)3.26042317
77monocyte chemotaxis (GO:0002548)3.25389466
78regulation of vitamin D biosynthetic process (GO:0060556)3.25125280
79regulation of cytokine secretion involved in immune response (GO:0002739)3.22368447
80myeloid dendritic cell differentiation (GO:0043011)3.20616291
81response to thyroid hormone (GO:0097066)3.18375053
82positive regulation of heat generation (GO:0031652)3.18007854
83negative regulation of nitric oxide biosynthetic process (GO:0045019)3.15116272
84regulation of cholesterol storage (GO:0010885)3.14844820
85positive regulation of p38MAPK cascade (GO:1900745)3.12665545
86regulation of podosome assembly (GO:0071801)3.11351087
87negative regulation of interleukin-6 production (GO:0032715)3.10431190
88positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.09886659
89barbed-end actin filament capping (GO:0051016)3.07032979
90cell adhesion mediated by integrin (GO:0033627)3.06821782
91detection of external biotic stimulus (GO:0098581)3.05918796
92membrane lipid catabolic process (GO:0046466)3.05763365
93adhesion of symbiont to host (GO:0044406)3.01826134
94negative regulation of interleukin-1 production (GO:0032692)3.00784890
95regulation of integrin activation (GO:0033623)2.99366152
96negative regulation of interleukin-1 beta production (GO:0032691)2.98300264
97interferon-gamma-mediated signaling pathway (GO:0060333)2.98154641
98positive regulation of monocyte chemotaxis (GO:0090026)2.97871825
99myeloid dendritic cell activation (GO:0001773)2.97710750
100neutrophil activation (GO:0042119)2.97046110
101regulation of chemokine biosynthetic process (GO:0045073)2.96809461
102response to lipoprotein particle (GO:0055094)2.96521886
103myeloid leukocyte mediated immunity (GO:0002444)2.95793096
104L-alpha-amino acid transmembrane transport (GO:1902475)2.95204419
105detection of other organism (GO:0098543)2.94311447
106positive regulation of cholesterol transport (GO:0032376)2.93248715
107positive regulation of sterol transport (GO:0032373)2.93248715
108macrophage differentiation (GO:0030225)2.92472541
109sphingolipid catabolic process (GO:0030149)2.91398696
110granulocyte activation (GO:0036230)2.89281904
111regulation of membrane protein ectodomain proteolysis (GO:0051043)2.87505974
112positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.87383881
113histamine secretion (GO:0001821)2.87153876
114regulation of mast cell degranulation (GO:0043304)2.85712874
115cytidine deamination (GO:0009972)2.84003577
116cytidine metabolic process (GO:0046087)2.84003577
117cytidine catabolic process (GO:0006216)2.84003577
118regulation of fever generation (GO:0031620)2.82179511
119positive regulation of interferon-beta production (GO:0032728)2.81502018
120leukocyte migration involved in inflammatory response (GO:0002523)2.80958083
121positive regulation of receptor recycling (GO:0001921)2.77642056
122basic amino acid transport (GO:0015802)2.77113762
123negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.76607020
124regulation of mast cell activation involved in immune response (GO:0033006)2.76062382
125positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.76046109
126modification by symbiont of host morphology or physiology (GO:0044003)2.74513722
127positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.74274679
128B cell homeostasis (GO:0001782)2.74050313
129cellular response to lipopolysaccharide (GO:0071222)2.73829656
130regulation of sequestering of triglyceride (GO:0010889)2.73741738
131regulation of antigen processing and presentation (GO:0002577)2.73078781
132negative regulation of myeloid cell apoptotic process (GO:0033033)2.72949754
133positive regulation of chemokine secretion (GO:0090197)2.72267571
134B cell mediated immunity (GO:0019724)2.71720866
135negative regulation of production of molecular mediator of immune response (GO:0002701)2.71621562
136detection of biotic stimulus (GO:0009595)2.71583485
137dendritic cell differentiation (GO:0097028)2.70346458
138viral entry into host cell (GO:0046718)2.69256094
139respiratory burst (GO:0045730)2.69232637
140regulation of dendritic cell antigen processing and presentation (GO:0002604)2.69062999
141regulation of T-helper 2 cell differentiation (GO:0045628)2.68365649
142response to laminar fluid shear stress (GO:0034616)2.68294735
143cellular response to molecule of bacterial origin (GO:0071219)2.68131708
144B cell receptor signaling pathway (GO:0050853)2.67639259
145response to protozoan (GO:0001562)2.67463781
146positive regulation of leukocyte apoptotic process (GO:2000108)2.64975657
147G-protein coupled receptor internalization (GO:0002031)2.64698183
148protein kinase C signaling (GO:0070528)2.64639471
149substrate-dependent cell migration (GO:0006929)2.64444852
150negative regulation of interleukin-17 production (GO:0032700)2.63084475
151positive regulation of T cell apoptotic process (GO:0070234)2.62930676
152positive regulation of phagocytosis (GO:0050766)2.61781860
153regulation of gamma-delta T cell activation (GO:0046643)2.61063535
154response to fluid shear stress (GO:0034405)2.60340046
155lysosome organization (GO:0007040)2.57977351
156lytic vacuole organization (GO:0080171)2.57977351
157low-density lipoprotein particle clearance (GO:0034383)2.57064567
158cellular extravasation (GO:0045123)2.55367023
159modulation by symbiont of host cellular process (GO:0044068)2.53330762
160regulation of gamma-delta T cell differentiation (GO:0045586)2.52199304
161regulation of mast cell activation (GO:0033003)2.51936997
162regulation of leukocyte degranulation (GO:0043300)2.51571904
163negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.49479494

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.00669200
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.93770215
3SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.62922003
4IRF8_22096565_ChIP-ChIP_GC-B_Human4.27033662
5IRF8_27001747_Chip-Seq_BMDM_Mouse4.23814406
6Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse4.23506883
7* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.48801260
8* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.84897601
9SCL_19346495_ChIP-Seq_HPC-7_Human2.75853745
10SPI1_23127762_ChIP-Seq_K562_Human2.74583505
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.72609615
12* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.40469164
13NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.37869466
14* GATA2_21666600_ChIP-Seq_HMVEC_Human2.33521017
15PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.28178631
16VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.26521897
17STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.20684639
18* BRD4_27068464_Chip-Seq_AML-cells_Mouse2.16906134
19VDR_24787735_ChIP-Seq_THP-1_Human2.10123934
20ESR1_21235772_ChIP-Seq_MCF-7_Human2.02326300
21PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.98504315
22VDR_21846776_ChIP-Seq_THP-1_Human1.98488158
23LXR_22158963_ChIP-Seq_LIVER_Mouse1.97182174
24VDR_24763502_ChIP-Seq_THP-1_Human1.91093318
25ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.89805325
26STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.88173721
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.81377502
28FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.76445446
29THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.74904038
30* PU_27001747_Chip-Seq_BMDM_Mouse1.73144979
31RXR_22158963_ChIP-Seq_LIVER_Mouse1.71450999
32SPI1_23547873_ChIP-Seq_NB4_Human1.70388435
33RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.70080215
34GATA1_22025678_ChIP-Seq_K562_Human1.68394581
35SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.62463813
36IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.59887144
37PPARA_22158963_ChIP-Seq_LIVER_Mouse1.54346479
38E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.51480995
39STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.47154046
40CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.46972218
41RUNX1_22412390_ChIP-Seq_EML_Mouse1.46885347
42RUNX_20019798_ChIP-Seq_JUKART_Human1.44974804
43IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.43802949
44TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.43783828
45NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.43480618
46FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.43107968
47KDM2B_26808549_Chip-Seq_SUP-B15_Human1.40236881
48TCF7_22412390_ChIP-Seq_EML_Mouse1.39619953
49FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.38707488
50NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.38420706
51GATA1_19941827_ChIP-Seq_MEL_Mouse1.36924438
52* ELK3_25401928_ChIP-Seq_HUVEC_Human1.36127562
53ESR2_21235772_ChIP-Seq_MCF-7_Human1.35943388
54STAT6_21828071_ChIP-Seq_BEAS2B_Human1.34259092
55* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.34156198
56CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.32299436
57SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.30578178
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.30463266
59GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.29873528
60GATA1_19941826_ChIP-Seq_K562_Human1.29035303
61MYC_22102868_ChIP-Seq_BL_Human1.27482816
62CDX2_19796622_ChIP-Seq_MESCs_Mouse1.25592159
63CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.21965045
64FOXO3_23340844_ChIP-Seq_DLD1_Human1.21116768
65* MAF_26560356_Chip-Seq_TH1_Human1.20419678
66CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.15229100
67GATA2_19941826_ChIP-Seq_K562_Human1.14259258
68NFIB_24661679_ChIP-Seq_LUNG_Mouse1.13380190
69IKZF1_21737484_ChIP-ChIP_HCT116_Human1.13307463
70STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.11788394
71KDM2B_26808549_Chip-Seq_K562_Human1.10936068
72GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10647040
73UTX_26944678_Chip-Seq_JUKART_Human1.10487679
74* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.09141779
75FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.08564948
76FOXA2_19822575_ChIP-Seq_HepG2_Human1.05720444
77BCL6_27268052_Chip-Seq_Bcells_Human1.04825059
78SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.04573579
79BCOR_27268052_Chip-Seq_Bcells_Human1.03587619
80KDM2B_26808549_Chip-Seq_DND41_Human1.03559589
81FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03555596
82STAT1_20625510_ChIP-Seq_HELA_Human1.02879603
83CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00942153
84STAT4_19710469_ChIP-ChIP_TH1__Mouse1.00813828
85MYB_26560356_Chip-Seq_TH1_Human1.00190443
86* MAF_26560356_Chip-Seq_TH2_Human1.00016537
87SRY_22984422_ChIP-ChIP_TESTIS_Rat1.00004631
88* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.99941933
89PPAR_26484153_Chip-Seq_NCI-H1993_Human0.99572208
90KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.99570989
91PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99311810
92TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.98411284
93ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.97822813
94BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97234878
95RARG_19884340_ChIP-ChIP_MEFs_Mouse0.96812461
96KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.96443501
97SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96063975
98VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.95302222
99CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.94804521
100TP63_17297297_ChIP-ChIP_HaCaT_Human0.93833350
101TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.92781511
102TFEB_21752829_ChIP-Seq_HELA_Human0.92465845
103LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.92001178
104RACK7_27058665_Chip-Seq_MCF-7_Human0.91846120
105ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.90681747
106PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90405280
107GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90082093
108ELF1_20517297_ChIP-Seq_JURKAT_Human0.90036696
109PU.1_20513432_ChIP-Seq_Bcells_Mouse0.89490561
110PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.88772953
111* LXR_22292898_ChIP-Seq_THP-1_Human0.88712622
112RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.88338267
113CLOCK_20551151_ChIP-Seq_293T_Human0.87768172
114LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.87026408
115SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86969666
116SOX9_24532713_ChIP-Seq_HFSC_Mouse0.86731815
117CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.85834137
118AHR_22903824_ChIP-Seq_MCF-7_Human0.85218575
119KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.84929662
120MYB_26560356_Chip-Seq_TH2_Human0.83995584
121DROSHA_22980978_ChIP-Seq_HELA_Human0.83995096
122TBX20_22080862_ChIP-Seq_HEART_Mouse0.83425910
123TBX20_22328084_ChIP-Seq_HEART_Mouse0.83425910

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation7.55459635
2MP0005058_abnormal_lysosome_morphology5.26371623
3MP0003172_abnormal_lysosome_physiology4.10355949
4MP0009840_abnormal_foam_cell2.88595576
5MP0005174_abnormal_tail_pigmentation2.81963314
6MP0001835_abnormal_antigen_presentation2.63565516
7MP0003303_peritoneal_inflammation2.59147562
8MP0003191_abnormal_cellular_cholesterol2.48989941
9MP0002419_abnormal_innate_immunity2.46902419
10MP0000015_abnormal_ear_pigmentation2.40574086
11MP0004510_myositis2.37558337
12MP0006082_CNS_inflammation2.32506411
13MP0003436_decreased_susceptibility_to2.23636927
14MP0005464_abnormal_platelet_physiology2.22913834
15MP0003300_gastrointestinal_ulcer2.22218116
16MP0009278_abnormal_bone_marrow2.20998200
17MP0003690_abnormal_glial_cell2.00762582
18MP0010368_abnormal_lymphatic_system1.97989724
19MP0005167_abnormal_blood-brain_barrier1.90231676
20MP0003183_abnormal_peptide_metabolism1.89255144
21MP0008004_abnormal_stomach_pH1.75939766
22MP0003724_increased_susceptibility_to1.73202496
23MP0003566_abnormal_cell_adhesion1.71633336
24MP0002452_abnormal_antigen_presenting1.68597319
25MP0005000_abnormal_immune_tolerance1.62525088
26MP0001800_abnormal_humoral_immune1.60303223
27MP0005387_immune_system_phenotype1.59863449
28MP0001790_abnormal_immune_system1.59863449
29MP0005257_abnormal_intraocular_pressure1.59022316
30MP0000604_amyloidosis1.57557721
31MP0005025_abnormal_response_to1.57394311
32MP0001879_abnormal_lymphatic_vessel1.50768342
33MP0002723_abnormal_immune_serum1.50320201
34MP0002166_altered_tumor_susceptibility1.50188901
35MP0005451_abnormal_body_composition1.49730791
36MP0005310_abnormal_salivary_gland1.49409679
37MP0000371_diluted_coat_color1.48449195
38MP0006054_spinal_hemorrhage1.46063620
39MP0003828_pulmonary_edema1.44708025
40MP0001958_emphysema1.44344891
41MP0003806_abnormal_nucleotide_metabolis1.43585468
42MP0008438_abnormal_cutaneous_collagen1.42874089
43MP0001533_abnormal_skeleton_physiology1.41933779
44MP0002254_reproductive_system_inflammat1.36847889
45MP0005670_abnormal_white_adipose1.36816402
46MP0003453_abnormal_keratinocyte_physiol1.36318258
47MP0000465_gastrointestinal_hemorrhage1.36271010
48MP0000685_abnormal_immune_system1.29665036
49MP0001819_abnormal_immune_cell1.29103589
50MP0002420_abnormal_adaptive_immunity1.27335771
51MP0002148_abnormal_hypersensitivity_rea1.27052130
52MP0008469_abnormal_protein_level1.25832358
53MP0004947_skin_inflammation1.22506691
54MP0000343_altered_response_to1.22479576
55MP0003705_abnormal_hypodermis_morpholog1.21663839
56MP0001851_eye_inflammation1.19951527
57MP0002138_abnormal_hepatobiliary_system1.15550606
58MP0003448_altered_tumor_morphology1.14641377
59MP0002405_respiratory_system_inflammati1.12682804
60MP0010307_abnormal_tumor_latency1.12183023
61MP0009333_abnormal_splenocyte_physiolog1.12118618
62MP0004130_abnormal_muscle_cell1.11864365
63MP0002998_abnormal_bone_remodeling1.10155199
64MP0000767_abnormal_smooth_muscle1.09601003
65MP0002396_abnormal_hematopoietic_system1.08207535
66MP0005165_increased_susceptibility_to1.06649007
67MP0003329_amyloid_beta_deposits1.06420113
68MP0001845_abnormal_inflammatory_respons1.05920167
69MP0005671_abnormal_response_to1.05303632
70MP0000920_abnormal_myelination1.05173827
71MP0003075_altered_response_to1.04881694
72MP0000689_abnormal_spleen_morphology1.02902305
73MP0005083_abnormal_biliary_tract1.01215459
74MP0001873_stomach_inflammation1.00803307
75MP0009785_altered_susceptibility_to1.00693579
76MP0005397_hematopoietic_system_phenotyp1.00147567
77MP0001545_abnormal_hematopoietic_system1.00147567
78MP0001915_intracranial_hemorrhage0.99509079
79MP0001542_abnormal_bone_strength0.98254863
80MP0001853_heart_inflammation0.97411740
81MP0002332_abnormal_exercise_endurance0.94807940
82MP0005360_urolithiasis0.93825748
83MP0009763_increased_sensitivity_to0.92991237
84MP0005164_abnormal_response_to0.91536999
85MP0002006_tumorigenesis0.90747560
86MP0000609_abnormal_liver_physiology0.90636925
87MP0005390_skeleton_phenotype0.90618467
88MP0001663_abnormal_digestive_system0.87818797
89MP0010329_abnormal_lipoprotein_level0.87686772
90MP0003091_abnormal_cell_migration0.87668589
91MP0000249_abnormal_blood_vessel0.86747929
92MP0003279_aneurysm0.86590383
93MP0004883_abnormal_blood_vessel0.85230714
94MP0000716_abnormal_immune_system0.84797079
95MP0004381_abnormal_hair_follicle0.82971231
96MP0005075_abnormal_melanosome_morpholog0.82594071
97MP0009764_decreased_sensitivity_to0.80872559
98MP0005595_abnormal_vascular_smooth0.80362142
99MP0003795_abnormal_bone_structure0.78916564
100MP0003656_abnormal_erythrocyte_physiolo0.78306281
101MP0003634_abnormal_glial_cell0.77437800
102MP0002933_joint_inflammation0.77420700
103MP0002722_abnormal_immune_system0.75733983
104MP0005197_abnormal_uvea_morphology0.75590542
105MP0005076_abnormal_cell_differentiation0.74191846
106MP0002398_abnormal_bone_marrow0.73216548
107MP0003252_abnormal_bile_duct0.71249163
108MP0010155_abnormal_intestine_physiology0.71124830
109MP0000858_altered_metastatic_potential0.70357501
110MP0001849_ear_inflammation0.70288590
111MP0005166_decreased_susceptibility_to0.70284756
112MP0002429_abnormal_blood_cell0.69985667
113MP0005647_abnormal_sex_gland0.68539690
114MP0004185_abnormal_adipocyte_glucose0.67858363
115MP0002877_abnormal_melanocyte_morpholog0.67747166
116MP0001243_abnormal_dermal_layer0.67370521
117MP0005365_abnormal_bile_salt0.67265365
118MP0002139_abnormal_hepatobiliary_system0.66949831
119MP0003195_calcinosis0.65081223
120MP0002277_abnormal_respiratory_mucosa0.65005710
121MP0005023_abnormal_wound_healing0.64652698
122MP0003045_fibrosis0.64513926
123MP0002928_abnormal_bile_duct0.64414712
124MP0002837_dystrophic_cardiac_calcinosis0.63324097
125MP0000598_abnormal_liver_morphology0.62510069
126MP0008260_abnormal_autophagy0.62411924
127MP0003879_abnormal_hair_cell0.58353227
128MP0008874_decreased_physiological_sensi0.57901801
129MP0002090_abnormal_vision0.57268636
130MP0005319_abnormal_enzyme/_coenzyme0.56612119
131MP0003633_abnormal_nervous_system0.55753419

Predicted human phenotypes

RankGene SetZ-score
1Systemic lupus erythematosus (HP:0002725)6.00037405
2Recurrent abscess formation (HP:0002722)5.86689888
3Recurrent bacterial skin infections (HP:0005406)5.71768024
4Increased cerebral lipofuscin (HP:0011813)5.58582073
5Vacuolated lymphocytes (HP:0001922)4.94240503
6Glomerulonephritis (HP:0000099)4.78319228
7Increased neuronal autofluorescent lipopigment (HP:0002074)4.69546143
8Abnormality of liposaccharide metabolism (HP:0010968)4.35121537
9Abnormality of glycosphingolipid metabolism (HP:0004343)4.35121537
10Abnormality of glycolipid metabolism (HP:0010969)4.35121537
11Dysostosis multiplex (HP:0000943)4.23332440
12Axonal loss (HP:0003447)4.16809072
13Complement deficiency (HP:0004431)4.02929394
14Eczematoid dermatitis (HP:0000976)3.67044665
15Nuclear cataract (HP:0100018)3.64361873
16Hematochezia (HP:0002573)3.59035014
17Neurofibrillary tangles (HP:0002185)3.58699380
18Disinhibition (HP:0000734)3.49067290
19Abnormality of mucopolysaccharide metabolism (HP:0011020)3.45059670
20Abnormality of polysaccharide metabolism (HP:0011012)3.45059670
21Abnormality of glycosaminoglycan metabolism (HP:0004371)3.45059670
22Gingivitis (HP:0000230)3.40176195
23Recurrent gram-negative bacterial infections (HP:0005420)3.39908914
24Periodontitis (HP:0000704)3.31919752
25Abnormality of complement system (HP:0005339)3.31814399
26Thick nail (HP:0001805)3.26700621
27Mucopolysacchariduria (HP:0008155)3.23325394
28Urinary glycosaminoglycan excretion (HP:0003541)3.23325394
29Cerebral aneurysm (HP:0004944)3.22333417
30Abnormality of macrophages (HP:0004311)3.21703599
31Recurrent skin infections (HP:0001581)3.19619161
32Autoimmune thrombocytopenia (HP:0001973)3.14113801
33Myocardial infarction (HP:0001658)3.10103559
34Nephritis (HP:0000123)3.09384243
35Pathologic fracture (HP:0002756)3.09068775
36Upper motor neuron abnormality (HP:0002127)2.98416174
37Optic neuritis (HP:0100653)2.93174187
38Retrobulbar optic neuritis (HP:0100654)2.93174187
39Prostate neoplasm (HP:0100787)2.92738448
40Joint hemorrhage (HP:0005261)2.80411422
41Elevated erythrocyte sedimentation rate (HP:0003565)2.79339323
42Peripheral demyelination (HP:0011096)2.79102023
43Global brain atrophy (HP:0002283)2.78419863
44Apathy (HP:0000741)2.78036612
45Amyloidosis (HP:0011034)2.77595100
46Purpura (HP:0000979)2.75899593
47Loss of speech (HP:0002371)2.75426021
48Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.70577440
49Spontaneous hematomas (HP:0007420)2.70106851
50Diminished motivation (HP:0000745)2.70038169
51Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.69543783
52Neuronal loss in central nervous system (HP:0002529)2.61433080
53Asymmetric septal hypertrophy (HP:0001670)2.56089843
54Increased serum ferritin (HP:0003281)2.55706454
55Thoracic kyphosis (HP:0002942)2.54921847
56Cerebral inclusion bodies (HP:0100314)2.54781289
57Premature loss of primary teeth (HP:0006323)2.53553290
58Urethral obstruction (HP:0000796)2.52911170
59Personality changes (HP:0000751)2.52298444
60Colitis (HP:0002583)2.50869807
61Gingival bleeding (HP:0000225)2.44313739
62Stomatitis (HP:0010280)2.42649087
63Progressive neurologic deterioration (HP:0002344)2.42111580
64Bone pain (HP:0002653)2.42109430
65Obstructive lung disease (HP:0006536)2.40927067
66Chronic obstructive pulmonary disease (HP:0006510)2.40927067
67Conjunctival telangiectasia (HP:0000524)2.36562003
68Abnormality of the vasculature of the conjunctiva (HP:0008054)2.35944719
69Distal lower limb amyotrophy (HP:0008944)2.33050989
70Neurodegeneration (HP:0002180)2.30797021
71Dementia (HP:0000726)2.26888731
72Increased CSF protein (HP:0002922)2.26241983
73Abnormal platelet function (HP:0011869)2.26151436
74Impaired platelet aggregation (HP:0003540)2.26151436
75Retinal atrophy (HP:0001105)2.25613949
76Agnosia (HP:0010524)2.24025844
77Hypercholesterolemia (HP:0003124)2.22372781
78Abnormality of the thoracic spine (HP:0100711)2.20674182
79Pustule (HP:0200039)2.18436300
80Recurrent fungal infections (HP:0002841)2.17951848
81Osteolytic defects of the hand bones (HP:0009699)2.16607101
82Osteolytic defects of the phalanges of the hand (HP:0009771)2.16607101
83Myositis (HP:0100614)2.16257297
84Pulmonary infiltrates (HP:0002113)2.16113916
85J-shaped sella turcica (HP:0002680)2.15929950
86Mediastinal lymphadenopathy (HP:0100721)2.15106268
87Hemoptysis (HP:0002105)2.13363585
88Abnormality of iron homeostasis (HP:0011031)2.11686385
89Petechiae (HP:0000967)2.10697155
90Pulmonary artery stenosis (HP:0004415)2.09773099
91Distal lower limb muscle weakness (HP:0009053)2.09562450
92Epistaxis (HP:0000421)2.08401630
93Disproportionate tall stature (HP:0001519)2.08066326
94Submucous cleft hard palate (HP:0000176)2.07899498
95Osteomyelitis (HP:0002754)2.07239524
96Bruising susceptibility (HP:0000978)2.07015371
97Hepatosplenomegaly (HP:0001433)2.03963190
98Polyneuropathy (HP:0001271)2.02150946
99Keratoconjunctivitis sicca (HP:0001097)2.01145410
100Prolonged bleeding time (HP:0003010)1.99284433
101Prolonged neonatal jaundice (HP:0006579)1.98587402
102Supranuclear gaze palsy (HP:0000605)1.94970837
103Inflammation of the large intestine (HP:0002037)1.92553314
104Malnutrition (HP:0004395)1.91894078
105Esophageal varix (HP:0002040)1.90846865
106Facial diplegia (HP:0001349)1.90763098
107Metaphyseal irregularity (HP:0003025)1.89932983
108Memory impairment (HP:0002354)1.88791018
109Cardiomegaly (HP:0001640)1.87448960
110Mutism (HP:0002300)1.87384258
111Abnormality of the nasal mucosa (HP:0000433)1.87145922
112Frequent falls (HP:0002359)1.85742149
113Progressive visual loss (HP:0000529)1.85400487
114Leukocytosis (HP:0001974)1.85104595
115Meningitis (HP:0001287)1.84027599
116Vertebral compression fractures (HP:0002953)1.83486893
117Abnormality of vision evoked potentials (HP:0000649)1.83481516
118Striae distensae (HP:0001065)1.83474842
119Orchitis (HP:0100796)1.83314745
120Arterial tortuosity (HP:0005116)1.81409082
121Aortic aneurysm (HP:0004942)1.80557431
122Abnormality of the periventricular white matter (HP:0002518)1.80467297
123Inappropriate behavior (HP:0000719)1.80442077
124Abnormality of the lumbar spine (HP:0100712)1.80393611
125Spondylolisthesis (HP:0003302)1.79933312
126Basal ganglia calcification (HP:0002135)1.79424450
127Acrocyanosis (HP:0001063)1.79130507
128Keratoconjunctivitis (HP:0001096)1.79061800
129Tetany (HP:0001281)1.78693561
130Large earlobe (HP:0009748)1.78224597
131Vasculitis (HP:0002633)1.77013701
132Absent frontal sinuses (HP:0002688)1.76534286
133Hypoalphalipoproteinemia (HP:0003233)1.76294793
134Recurrent viral infections (HP:0004429)1.74883140
135Pulmonary embolism (HP:0002204)1.74299017
136Interstitial pulmonary disease (HP:0006530)1.73335949
137Mucosal telangiectasiae (HP:0100579)1.71087392
138Joint stiffness (HP:0001387)1.69222241
139Abnormality of transition element cation homeostasis (HP:0011030)1.67016866

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR24.27554027
2NME23.32647794
3CAMK1D3.19685489
4TAOK33.06649375
5KIT3.01474142
6CAMK1G2.90619349
7TYK22.85951454
8RIPK42.63587630
9TIE12.63381124
10TTN2.57810349
11DDR22.50785606
12BLK2.48599065
13IRAK32.45612593
14KDR2.38081274
15CSF1R2.32260395
16MAP3K142.27831581
17MAP3K112.22177028
18SIK22.11767440
19TBK12.08044593
20PRPF4B2.07264547
21FES2.06602383
22TAOK22.04072081
23IRAK42.02387049
24ERN11.92172990
25JAK11.79466509
26TAOK11.75072293
27PTK61.69033885
28MAP2K31.57827463
29HCK1.56835382
30CDC42BPA1.50575599
31MAP4K11.49001575
32ACVR1B1.46120890
33EPHB11.43155928
34DAPK21.40526687
35RIPK11.39847585
36MOS1.36150275
37IKBKB1.33030227
38ABL21.31967073
39NEK91.29953965
40ZAP701.27339471
41IKBKE1.27039467
42MAP3K131.26601920
43PIM21.24819810
44JAK31.22899071
45CDK121.20757262
46CSK1.20230719
47GRK71.16254707
48CDK61.16199735
49JAK21.12555464
50FGR1.12017678
51SCYL21.11083285
52TRIB31.10754694
53TGFBR11.08925811
54CLK11.06372162
55MAP3K11.05395140
56MAPK121.02270974
57MAP3K31.02179729
58PKN20.99713177
59LCK0.99585589
60PAK40.97770992
61TNK20.92930543
62PTK2B0.89497503
63LYN0.87260368
64EGFR0.87218510
65CAMKK20.86804392
66TESK20.85839539
67SYK0.84858887
68TESK10.84068302
69MAPK70.83291285
70ADRBK20.81557449
71IRAK20.80779589
72PKN10.78981510
73CHUK0.78197168
74BTK0.75915199
75SGK30.74599400
76BRD40.74414645
77BMPR20.73719606
78EPHB20.71484752
79ICK0.69881236
80MAP2K60.69686808
81MAPK150.67978700
82IRAK10.66744328
83ITK0.66738077
84MAP3K50.66529286
85SGK20.66336822
86TRPM70.66225003
87STK100.64990585
88TYRO30.64088944
89CAMK40.64078260
90PRKAA20.63579233
91TEC0.62935914
92PDGFRA0.62831424
93PDGFRB0.61981229
94MARK20.58215402
95RPS6KC10.56935003
96RPS6KL10.56935003
97MAP3K100.56709208
98MTOR0.56470019
99PTK20.56041307
100YES10.53872834
101PDPK10.53795091
102TXK0.53485489
103ABL10.50866635
104INSRR0.50614320
105SIK30.49894095
106SIK10.49187979
107MAPK40.48368529
108FYN0.47602843
109PAK20.47121951
110SRC0.45884173
111PDK10.45613003
112MARK30.44379901
113IGF1R0.44149733
114MAP3K60.43395767
115FGFR40.42593866
116GSK3A0.42572060
117PIK3CG0.42530302
118CAMKK10.42254929
119SGK10.40945046
120RPS6KA20.40816843
121EIF2AK20.39705398
122PRKD20.39646783
123CDK90.38442541
124DAPK30.37819277
125PIM10.37789443
126BMX0.37679717
127DMPK0.37183193
128PRKD10.36407854
129STK40.34588746
130ARAF0.33758936
131MATK0.33442822
132PRKG20.33184815
133ERBB20.32711092
134PRKCD0.30741993
135CDK40.30094829
136INSR0.29356429
137RPS6KA60.28127143

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051504.14360366
2Glycosaminoglycan degradation_Homo sapiens_hsa005313.85979890
3Lysosome_Homo sapiens_hsa041423.19681973
4Other glycan degradation_Homo sapiens_hsa005113.12581608
5Caffeine metabolism_Homo sapiens_hsa002322.84865722
6Osteoclast differentiation_Homo sapiens_hsa043802.54741260
7Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.32797257
8Asthma_Homo sapiens_hsa053102.24164317
9Complement and coagulation cascades_Homo sapiens_hsa046102.19882085
10Allograft rejection_Homo sapiens_hsa053302.14875963
11Leishmaniasis_Homo sapiens_hsa051402.09996225
12Toll-like receptor signaling pathway_Homo sapiens_hsa046202.08053995
13Pertussis_Homo sapiens_hsa051331.97312218
14B cell receptor signaling pathway_Homo sapiens_hsa046621.94775330
15Malaria_Homo sapiens_hsa051441.87375186
16Graft-versus-host disease_Homo sapiens_hsa053321.85732144
17Autoimmune thyroid disease_Homo sapiens_hsa053201.76311616
18Tuberculosis_Homo sapiens_hsa051521.73635241
19Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.71468822
20NF-kappa B signaling pathway_Homo sapiens_hsa040641.58970495
21Phagosome_Homo sapiens_hsa041451.58651395
22Lysine degradation_Homo sapiens_hsa003101.39115331
23Type I diabetes mellitus_Homo sapiens_hsa049401.37258677
24Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.33948162
25ABC transporters_Homo sapiens_hsa020101.31745357
26Measles_Homo sapiens_hsa051621.31122252
27Toxoplasmosis_Homo sapiens_hsa051451.29775813
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.29351938
29Influenza A_Homo sapiens_hsa051641.23439594
30Rheumatoid arthritis_Homo sapiens_hsa053231.19045927
31Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.13842082
32Type II diabetes mellitus_Homo sapiens_hsa049301.11196176
33Chronic myeloid leukemia_Homo sapiens_hsa052201.09488531
34Apoptosis_Homo sapiens_hsa042101.04476305
35Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.03144568
36Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.03061808
37TNF signaling pathway_Homo sapiens_hsa046681.01111432
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.96796304
39Chemokine signaling pathway_Homo sapiens_hsa040620.95906224
40Legionellosis_Homo sapiens_hsa051340.94811943
41Leukocyte transendothelial migration_Homo sapiens_hsa046700.94504960
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91036640
43RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.90821034
44Platelet activation_Homo sapiens_hsa046110.90140864
45Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.89652651
46Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.88149729
47Hepatitis C_Homo sapiens_hsa051600.87750421
48Primary bile acid biosynthesis_Homo sapiens_hsa001200.87412940
49Salmonella infection_Homo sapiens_hsa051320.86742069
50PPAR signaling pathway_Homo sapiens_hsa033200.86440084
51Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.85272042
52Hematopoietic cell lineage_Homo sapiens_hsa046400.84734664
53AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.84713833
54Amoebiasis_Homo sapiens_hsa051460.83678510
55Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.83529804
56Bladder cancer_Homo sapiens_hsa052190.83224834
57Collecting duct acid secretion_Homo sapiens_hsa049660.80891842
58Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80865001
59Pancreatic cancer_Homo sapiens_hsa052120.80417715
60Prion diseases_Homo sapiens_hsa050200.80224270
61African trypanosomiasis_Homo sapiens_hsa051430.79384939
62Pentose and glucuronate interconversions_Homo sapiens_hsa000400.78702712
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76597544
64Insulin resistance_Homo sapiens_hsa049310.76489517
65Carbohydrate digestion and absorption_Homo sapiens_hsa049730.76407475
66Sphingolipid metabolism_Homo sapiens_hsa006000.76211324
67Endocytosis_Homo sapiens_hsa041440.74699305
68Notch signaling pathway_Homo sapiens_hsa043300.74254722
69Acute myeloid leukemia_Homo sapiens_hsa052210.70856479
70Jak-STAT signaling pathway_Homo sapiens_hsa046300.70335110
71Nitrogen metabolism_Homo sapiens_hsa009100.69846420
72Antigen processing and presentation_Homo sapiens_hsa046120.67292193
73Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64927992
74Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64618184
75Shigellosis_Homo sapiens_hsa051310.64573434
76Hepatitis B_Homo sapiens_hsa051610.64528766
77Small cell lung cancer_Homo sapiens_hsa052220.64448099
78Regulation of actin cytoskeleton_Homo sapiens_hsa048100.64213668
79Mineral absorption_Homo sapiens_hsa049780.62917773
80Vibrio cholerae infection_Homo sapiens_hsa051100.61878434
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.59096050
82Prolactin signaling pathway_Homo sapiens_hsa049170.57919774
83Focal adhesion_Homo sapiens_hsa045100.56629948
84Sphingolipid signaling pathway_Homo sapiens_hsa040710.56362222
85Phospholipase D signaling pathway_Homo sapiens_hsa040720.55524337
86Galactose metabolism_Homo sapiens_hsa000520.53661085
87Inositol phosphate metabolism_Homo sapiens_hsa005620.53382174
88Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52633828
89Dorso-ventral axis formation_Homo sapiens_hsa043200.52522165
90Primary immunodeficiency_Homo sapiens_hsa053400.52316522
91Starch and sucrose metabolism_Homo sapiens_hsa005000.51660856
92Viral myocarditis_Homo sapiens_hsa054160.51429097
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50844787
94T cell receptor signaling pathway_Homo sapiens_hsa046600.50540126
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.50373907
96Proteoglycans in cancer_Homo sapiens_hsa052050.48237259
97Intestinal immune network for IgA production_Homo sapiens_hsa046720.47808053
98Epstein-Barr virus infection_Homo sapiens_hsa051690.45691848
99Herpes simplex infection_Homo sapiens_hsa051680.45274679
100Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.44400999
101Fatty acid degradation_Homo sapiens_hsa000710.42694473
102ECM-receptor interaction_Homo sapiens_hsa045120.41406651
103Arginine biosynthesis_Homo sapiens_hsa002200.40320759
104Bile secretion_Homo sapiens_hsa049760.40304469
105VEGF signaling pathway_Homo sapiens_hsa043700.40113824
106Renin-angiotensin system_Homo sapiens_hsa046140.39697461
107HIF-1 signaling pathway_Homo sapiens_hsa040660.38305816
108Systemic lupus erythematosus_Homo sapiens_hsa053220.37584365
109MicroRNAs in cancer_Homo sapiens_hsa052060.36088932
110GnRH signaling pathway_Homo sapiens_hsa049120.36049380
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33552912
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33114723
113Renal cell carcinoma_Homo sapiens_hsa052110.32584181
114Dilated cardiomyopathy_Homo sapiens_hsa054140.32540941
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.31848713
116mTOR signaling pathway_Homo sapiens_hsa041500.31418490
117HTLV-I infection_Homo sapiens_hsa051660.30117913
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29890558
119Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29812187
120Insulin signaling pathway_Homo sapiens_hsa049100.29186562
121Synaptic vesicle cycle_Homo sapiens_hsa047210.23394003
122Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.21849483
123Sulfur metabolism_Homo sapiens_hsa009200.18454021
124Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.18052239
125Fructose and mannose metabolism_Homo sapiens_hsa000510.16583638
126MAPK signaling pathway_Homo sapiens_hsa040100.16524214

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