STAMBPL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.49833106
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.09762858
3positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.95777678
4B cell receptor signaling pathway (GO:0050853)4.94103486
5antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.92206469
6antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.92206469
7regulation of gamma-delta T cell differentiation (GO:0045586)4.83678203
8positive regulation of B cell differentiation (GO:0045579)4.62887248
9leukocyte aggregation (GO:0070486)4.59996590
10regulation of gamma-delta T cell activation (GO:0046643)4.46338008
11antigen processing and presentation of endogenous antigen (GO:0019883)4.30847055
12regulation of B cell receptor signaling pathway (GO:0050855)4.17631460
13regulation of B cell differentiation (GO:0045577)4.13074249
14negative regulation of phagocytosis (GO:0050765)4.02562167
15positive regulation of natural killer cell differentiation (GO:0032825)3.93178094
16T cell migration (GO:0072678)3.92878164
17mast cell activation (GO:0045576)3.85242724
18positive regulation of defense response to virus by host (GO:0002230)3.81991983
19negative T cell selection (GO:0043383)3.79205228
20positive thymic T cell selection (GO:0045059)3.74925019
21negative thymic T cell selection (GO:0045060)3.73681901
22negative regulation of cell killing (GO:0031342)3.71805722
23negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.71805722
24DNA deamination (GO:0045006)3.71545885
25antigen receptor-mediated signaling pathway (GO:0050851)3.70255334
26neutrophil activation involved in immune response (GO:0002283)3.70030494
27positive regulation of T cell mediated cytotoxicity (GO:0001916)3.57451025
28V(D)J recombination (GO:0033151)3.55913539
29Arp2/3 complex-mediated actin nucleation (GO:0034314)3.55608176
30fucose catabolic process (GO:0019317)3.55414759
31L-fucose metabolic process (GO:0042354)3.55414759
32L-fucose catabolic process (GO:0042355)3.55414759
33positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.52001649
34natural killer cell differentiation (GO:0001779)3.51005816
35positive regulation of macrophage differentiation (GO:0045651)3.50310981
36regulation of T cell mediated cytotoxicity (GO:0001914)3.49944083
37sequestering of actin monomers (GO:0042989)3.49057636
38tolerance induction (GO:0002507)3.48287132
39positive regulation of natural killer cell mediated immunity (GO:0002717)3.46458412
40response to interleukin-15 (GO:0070672)3.45055417
41rRNA catabolic process (GO:0016075)3.40497475
42sulfation (GO:0051923)3.40101263
43positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.39597750
44positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.38999846
45T cell receptor signaling pathway (GO:0050852)3.37891609
46regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.35966134
47T cell homeostasis (GO:0043029)3.34839943
48positive regulation of protein homodimerization activity (GO:0090073)3.34684230
49positive regulation of alpha-beta T cell proliferation (GO:0046641)3.30714718
50regulation of leukocyte mediated cytotoxicity (GO:0001910)3.28611895
51cellular response to exogenous dsRNA (GO:0071360)3.28415844
52regulation of alpha-beta T cell proliferation (GO:0046640)3.27647647
53activated T cell proliferation (GO:0050798)3.27493127
54negative regulation of mast cell activation (GO:0033004)3.26993426
55cellular response to interleukin-15 (GO:0071350)3.26782911
56regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.24276249
57antigen processing and presentation via MHC class Ib (GO:0002475)3.23868047
58T cell costimulation (GO:0031295)3.22047205
59immunoglobulin mediated immune response (GO:0016064)3.21449071
60T cell selection (GO:0045058)3.20120197
61lymphocyte costimulation (GO:0031294)3.19538943
62regulation of natural killer cell mediated immunity (GO:0002715)3.19197288
63regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.19197288
64mast cell activation involved in immune response (GO:0002279)3.17762077
65mast cell degranulation (GO:0043303)3.17762077
66B cell proliferation (GO:0042100)3.15290604
67positive regulation of cell killing (GO:0031343)3.14705882
68behavioral response to nicotine (GO:0035095)3.14545280
69cellular extravasation (GO:0045123)3.14257063
70regulation of T cell receptor signaling pathway (GO:0050856)3.12780381
71positive T cell selection (GO:0043368)3.12217430
72interferon-gamma production (GO:0032609)3.08977919
73response to gravity (GO:0009629)3.07879488
74regulation of defense response to virus by host (GO:0050691)3.07031496
75regulation of regulatory T cell differentiation (GO:0045589)3.02903646
76interferon-gamma-mediated signaling pathway (GO:0060333)3.00171638
77thymic T cell selection (GO:0045061)2.99243107
78negative regulation of T cell mediated immunity (GO:0002710)2.98846995
79neutrophil activation (GO:0042119)2.98765364
80sleep (GO:0030431)2.98023118
81respiratory burst (GO:0045730)2.97311664
82regulation of cell killing (GO:0031341)2.97240168
83myeloid cell activation involved in immune response (GO:0002275)2.96924002
84positive regulation of granulocyte differentiation (GO:0030854)2.96506726
85lymphocyte homeostasis (GO:0002260)2.96230831
86leukocyte cell-cell adhesion (GO:0007159)2.95652526
87defense response to protozoan (GO:0042832)2.94653345
88regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.94558010
89NIK/NF-kappaB signaling (GO:0038061)2.93617969
90regulation of RIG-I signaling pathway (GO:0039535)2.93615866
91hepatocyte apoptotic process (GO:0097284)2.90984904
92response to protozoan (GO:0001562)2.90794836
93immune response-activating cell surface receptor signaling pathway (GO:0002429)2.89595567
94positive regulation of interleukin-2 production (GO:0032743)2.89540912
95regulation of interleukin-12 biosynthetic process (GO:0045075)2.87502223
96modulation by symbiont of host defense response (GO:0052031)2.85545962
97modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.85545962
98modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.85545962
99positive regulation by organism of defense response of other organism involved in symbiotic interact2.85545962
100modulation by symbiont of host immune response (GO:0052553)2.85545962
101positive regulation by symbiont of host defense response (GO:0052509)2.85545962
102myeloid dendritic cell activation (GO:0001773)2.83320541
103macrophage activation involved in immune response (GO:0002281)2.83284444
104positive regulation of lamellipodium assembly (GO:0010592)2.81244508
105positive regulation of interferon-alpha production (GO:0032727)2.80529303
106regulation of T cell tolerance induction (GO:0002664)2.79729616
107cAMP catabolic process (GO:0006198)2.79490737
108cellular response to interferon-beta (GO:0035458)2.78975967
109natural killer cell activation (GO:0030101)2.78709163
110response to type I interferon (GO:0034340)2.78115426
111granulocyte activation (GO:0036230)2.78040004
112regulation of interferon-beta biosynthetic process (GO:0045357)2.76304763
113mucosal-associated lymphoid tissue development (GO:0048537)2.74909316
114Peyers patch development (GO:0048541)2.74909316
115isotype switching (GO:0045190)2.74889930
116somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.74889930
117somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.74889930
118positive regulation of isotype switching (GO:0045830)2.73875251
119cellular response to dsRNA (GO:0071359)2.73717994
120cellular response to type I interferon (GO:0071357)2.72947844
121type I interferon signaling pathway (GO:0060337)2.72947844
122regulation of isotype switching to IgG isotypes (GO:0048302)2.72599392
123regulation of necroptotic process (GO:0060544)2.71766932
124CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.71525009
125mature B cell differentiation (GO:0002335)2.70077283
126actin nucleation (GO:0045010)2.68774745
127negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.68301922
128cellular response to ATP (GO:0071318)2.67727116
129mononuclear cell proliferation (GO:0032943)2.67622031
130B cell mediated immunity (GO:0019724)2.67272256
131regulation of interferon-alpha production (GO:0032647)2.67156681
132cytidine deamination (GO:0009972)2.66537919
133cytidine metabolic process (GO:0046087)2.66537919
134cytidine catabolic process (GO:0006216)2.66537919
135lymphocyte proliferation (GO:0046651)2.66204084
136regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.65331501
137positive regulation of T cell mediated immunity (GO:0002711)2.64992849
138T cell proliferation (GO:0042098)2.64082869
139pyrimidine ribonucleoside catabolic process (GO:0046133)2.63503803
140positive regulation of tolerance induction (GO:0002645)2.63031993
141protein K11-linked deubiquitination (GO:0035871)2.62178422
142regulation of natural killer cell differentiation (GO:0032823)2.62021216
143positive regulation of T cell cytokine production (GO:0002726)2.61962221
144response to pheromone (GO:0019236)2.61946344
145interkinetic nuclear migration (GO:0022027)2.61136834
146replicative senescence (GO:0090399)2.60962557
147regulation of type I interferon-mediated signaling pathway (GO:0060338)2.60806738
148T cell lineage commitment (GO:0002360)2.60690166
149positive regulation of T cell differentiation in thymus (GO:0033089)2.60128021
150alpha-beta T cell differentiation (GO:0046632)2.59622773
151response to interferon-beta (GO:0035456)2.55063291
152cyclic nucleotide catabolic process (GO:0009214)2.53646838
153alpha-beta T cell activation (GO:0046631)2.52922703
154positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.52524279
155positive regulation of T-helper 1 type immune response (GO:0002827)2.52133609
156tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.51889171
157RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.51889171
158negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.49379718
159L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.46193439
160negative regulation by host of viral transcription (GO:0043922)2.45683432
161negative regulation of lymphocyte mediated immunity (GO:0002707)2.42853685
162indolalkylamine metabolic process (GO:0006586)2.39794268
163pseudouridine synthesis (GO:0001522)2.39519561

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.98059632
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.97134196
3E2F7_22180533_ChIP-Seq_HELA_Human4.57246315
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.21728485
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.14039740
6* IRF8_21731497_ChIP-ChIP_J774_Mouse3.96368190
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.53531424
8SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.47341667
9MYC_22102868_ChIP-Seq_BL_Human3.37601619
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.12520602
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.93639056
12STAT4_19710469_ChIP-ChIP_TH1__Mouse2.84051462
13RUNX_20019798_ChIP-Seq_JUKART_Human2.83777414
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.80391912
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.78834406
16* MYB_26560356_Chip-Seq_TH2_Human2.77923863
17* IRF8_27001747_Chip-Seq_BMDM_Mouse2.74208621
18VDR_21846776_ChIP-Seq_THP-1_Human2.72507710
19ZNF274_21170338_ChIP-Seq_K562_Hela2.67391359
20* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.61945488
21IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.58692774
22BP1_19119308_ChIP-ChIP_Hs578T_Human2.58246253
23MYB_21317192_ChIP-Seq_ERMYB_Mouse2.55872289
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.51712910
25RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.49820194
26FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.46829399
27* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.46329625
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.42485072
29SCL_19346495_ChIP-Seq_HPC-7_Human2.40378800
30VDR_24763502_ChIP-Seq_THP-1_Human2.34259710
31MAF_26560356_Chip-Seq_TH1_Human2.32996153
32MYB_26560356_Chip-Seq_TH1_Human2.32978731
33* SPI1_23547873_ChIP-Seq_NB4_Human2.29029730
34UTX_26944678_Chip-Seq_JUKART_Human2.27108822
35ZFP57_27257070_Chip-Seq_ESCs_Mouse2.25689303
36E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.23513944
37FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.17609913
38* ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.17440215
39FOXM1_23109430_ChIP-Seq_U2OS_Human2.12893597
40PCGF2_27294783_Chip-Seq_ESCs_Mouse2.12451601
41VDR_22108803_ChIP-Seq_LS180_Human2.11915952
42POU3F2_20337985_ChIP-ChIP_501MEL_Human2.03092403
43RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.98512213
44GBX2_23144817_ChIP-Seq_PC3_Human1.96385936
45RUNX1_22412390_ChIP-Seq_EML_Mouse1.92006573
46* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.91617257
47NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.90786085
48TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.89027905
49E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.88195580
50CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.87523293
51EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.86316100
52HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.84948370
53FUS_26573619_Chip-Seq_HEK293_Human1.82727142
54GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.80636066
55PCGF2_27294783_Chip-Seq_NPCs_Mouse1.72335594
56SPI1_23127762_ChIP-Seq_K562_Human1.69993592
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.69791176
58MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.67629224
59E2F4_17652178_ChIP-ChIP_JURKAT_Human1.66399506
60BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.66325109
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.65937258
62NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.60225929
63GATA3_27048872_Chip-Seq_THYMUS_Human1.53971088
64* PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.53521699
65TCF7_22412390_ChIP-Seq_EML_Mouse1.53031079
66HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.51297719
67GATA1_22025678_ChIP-Seq_K562_Human1.50921992
68TAF15_26573619_Chip-Seq_HEK293_Human1.49309283
69EWS_26573619_Chip-Seq_HEK293_Human1.46008204
70ELF1_17652178_ChIP-ChIP_JURKAT_Human1.43998758
71LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.41803011
72* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.40287850
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.40230161
74PU_27001747_Chip-Seq_BMDM_Mouse1.39720429
75EST1_17652178_ChIP-ChIP_JURKAT_Human1.39649576
76SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.39528121
77HOXB4_20404135_ChIP-ChIP_EML_Mouse1.39206775
78* MAF_26560356_Chip-Seq_TH2_Human1.38722774
79GATA2_22383799_ChIP-Seq_G1ME_Mouse1.38596780
80P300_19829295_ChIP-Seq_ESCs_Human1.38446576
81EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.38129630
82SUZ12_27294783_Chip-Seq_NPCs_Mouse1.37691065
83ER_23166858_ChIP-Seq_MCF-7_Human1.37572532
84MYC_18940864_ChIP-ChIP_HL60_Human1.37486626
85VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36714780
86NOTCH1_21737748_ChIP-Seq_TLL_Human1.36402040
87NFE2_27457419_Chip-Seq_LIVER_Mouse1.35515817
88PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.34643119
89GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.32700638
90VDR_23849224_ChIP-Seq_CD4+_Human1.32613593
91TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32344450
92CTBP1_25329375_ChIP-Seq_LNCAP_Human1.31404649
93PRDM14_20953172_ChIP-Seq_ESCs_Human1.30187994
94RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.29589273
95CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28971486
96IRF1_19129219_ChIP-ChIP_H3396_Human1.27907441
97TP53_22573176_ChIP-Seq_HFKS_Human1.25545367
98Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.24137518
99* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.23727176
100IGF1R_20145208_ChIP-Seq_DFB_Human1.22731104
101AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.22591177
102* STAT3_23295773_ChIP-Seq_U87_Human1.22538836
103SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.21681538
104EZH2_27294783_Chip-Seq_NPCs_Mouse1.20191579
105FOXP3_21729870_ChIP-Seq_TREG_Human1.19678013
106MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.19453247
107NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.16837282
108CIITA_25753668_ChIP-Seq_RAJI_Human1.12919862
109FOXA1_25329375_ChIP-Seq_VCAP_Human1.12871607
110FOXA1_27270436_Chip-Seq_PROSTATE_Human1.12871607
111UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12387066
112LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.12227194
113* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10976292
114BCAT_22108803_ChIP-Seq_LS180_Human1.10808268
115* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09968592
116TCF4_23295773_ChIP-Seq_U87_Human1.09296199
117ELK1_19687146_ChIP-ChIP_HELA_Human1.08300546
118KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.08280383
119SMAD4_21799915_ChIP-Seq_A2780_Human1.07141141
120KDM2B_26808549_Chip-Seq_DND41_Human1.06583461
121TP53_16413492_ChIP-PET_HCT116_Human1.06110018
122GATA3_26560356_Chip-Seq_TH2_Human1.05463467
123TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.04984221
124CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.04252334
125PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.02677427
126GATA3_26560356_Chip-Seq_TH1_Human1.01405431
127KDM2B_26808549_Chip-Seq_SUP-B15_Human1.01122169
128FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.00402226
129* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.00210078
130* CBP_20019798_ChIP-Seq_JUKART_Human1.00210078
131VDR_24787735_ChIP-Seq_THP-1_Human0.99792585
132NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99650552
133* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.98711443
134* RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.98234112
135FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98094113
136ELK3_25401928_ChIP-Seq_HUVEC_Human0.97248441
137AR_20517297_ChIP-Seq_VCAP_Human0.96403035
138SRF_21415370_ChIP-Seq_HL-1_Mouse0.95230299
139GATA1_22383799_ChIP-Seq_G1ME_Mouse0.95047813
140* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.94010588
141PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93887684
142GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.91972991
143SMRT_27268052_Chip-Seq_Bcells_Human0.91333993
144CRX_20693478_ChIP-Seq_RETINA_Mouse0.90401502
145* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90347659
146FLI1_21867929_ChIP-Seq_TH2_Mouse0.90297350
147TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.89949677
148SMAD_19615063_ChIP-ChIP_OVARY_Human0.88483830
149NANOG_18555785_Chip-Seq_ESCs_Mouse0.88235816
150PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87346865
151NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.87326895
152TCF4_22108803_ChIP-Seq_LS180_Human0.87262149
153* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86699520
154* CDX2_22108803_ChIP-Seq_LS180_Human0.86539883
155OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.86423180
156ETS1_20019798_ChIP-Seq_JURKAT_Human0.86158195
157P53_22387025_ChIP-Seq_ESCs_Mouse0.85217195
158EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.85145637
159* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84522835
160STAT3_18555785_Chip-Seq_ESCs_Mouse0.84518420
161GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.83744783
162E2F1_21310950_ChIP-Seq_MCF-7_Human0.83247985
163JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82844255
164FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.80556072
165HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.78536594
166RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75714562
167GABP_17652178_ChIP-ChIP_JURKAT_Human0.75636087
168* ETS1_22383799_ChIP-Seq_G1ME_Mouse0.74140242
169* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.73694286

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.97468891
2MP0000685_abnormal_immune_system3.58032066
3MP0005671_abnormal_response_to3.57938348
4MP0001800_abnormal_humoral_immune3.27309670
5MP0009785_altered_susceptibility_to3.14348504
6MP0003763_abnormal_thymus_physiology3.08896963
7MP0002452_abnormal_antigen_presenting2.93342017
8MP0005000_abnormal_immune_tolerance2.92319706
9MP0001790_abnormal_immune_system2.87018105
10MP0005387_immune_system_phenotype2.87018105
11MP0003436_decreased_susceptibility_to2.86853677
12MP0002396_abnormal_hematopoietic_system2.79249714
13MP0002723_abnormal_immune_serum2.76233547
14MP0002420_abnormal_adaptive_immunity2.75414265
15MP0002166_altered_tumor_susceptibility2.74820897
16MP0001819_abnormal_immune_cell2.72847205
17MP0002398_abnormal_bone_marrow2.66447557
18MP0005025_abnormal_response_to2.51988067
19MP0002006_tumorigenesis2.44023822
20MP0003303_peritoneal_inflammation2.41775009
21MP0002419_abnormal_innate_immunity2.37276158
22MP0002148_abnormal_hypersensitivity_rea2.35890367
23MP0000716_abnormal_immune_system2.34804683
24MP0000689_abnormal_spleen_morphology2.23259469
25MP0004808_abnormal_hematopoietic_stem2.21664132
26MP0002722_abnormal_immune_system2.17022304
27MP0002405_respiratory_system_inflammati2.16584004
28MP0000703_abnormal_thymus_morphology2.15667505
29MP0009333_abnormal_splenocyte_physiolog2.08132572
30MP0003724_increased_susceptibility_to2.01053507
31MP0003300_gastrointestinal_ulcer2.00649171
32MP0006054_spinal_hemorrhage1.96624711
33MP0002138_abnormal_hepatobiliary_system1.95611841
34MP0002429_abnormal_blood_cell1.93257058
35MP0006082_CNS_inflammation1.92331140
36MP0004947_skin_inflammation1.89596136
37MP0005464_abnormal_platelet_physiology1.85253526
38MP0010155_abnormal_intestine_physiology1.84813946
39MP0006072_abnormal_retinal_apoptosis1.74646793
40MP0009278_abnormal_bone_marrow1.70793855
41MP0004142_abnormal_muscle_tone1.68637327
42MP0002933_joint_inflammation1.67200410
43MP0001845_abnormal_inflammatory_respons1.65513346
44MP0000372_irregular_coat_pigmentation1.64884107
45MP0005397_hematopoietic_system_phenotyp1.64876517
46MP0001545_abnormal_hematopoietic_system1.64876517
47MP0001853_heart_inflammation1.64710413
48MP0000858_altered_metastatic_potential1.57295832
49MP0001873_stomach_inflammation1.56559467
50MP0001348_abnormal_lacrimal_gland1.56547537
51MP0003866_abnormal_defecation1.56430322
52MP0005551_abnormal_eye_electrophysiolog1.55727399
53MP0008877_abnormal_DNA_methylation1.54902141
54MP0002102_abnormal_ear_morphology1.52551002
55MP0001533_abnormal_skeleton_physiology1.52454650
56MP0008872_abnormal_physiological_respon1.50990102
57MP0003172_abnormal_lysosome_physiology1.41238534
58MP0000490_abnormal_crypts_of1.41068310
59MP0003283_abnormal_digestive_organ1.40679205
60MP0002928_abnormal_bile_duct1.38710413
61MP0005084_abnormal_gallbladder_morpholo1.36936448
62MP0000427_abnormal_hair_cycle1.35437684
63MP0002163_abnormal_gland_morphology1.34654212
64MP0003252_abnormal_bile_duct1.33729008
65MP0001968_abnormal_touch/_nociception1.33152854
66MP0002876_abnormal_thyroid_physiology1.31978935
67MP0003950_abnormal_plasma_membrane1.31504002
68MP0003786_premature_aging1.29923904
69MP0010352_gastrointestinal_tract_polyps1.28056996
70MP0001501_abnormal_sleep_pattern1.27259034
71MP0003787_abnormal_imprinting1.24944073
72MP0005410_abnormal_fertilization1.24096137
73MP0000013_abnormal_adipose_tissue1.23098870
74MP0004134_abnormal_chest_morphology1.21444509
75MP0002272_abnormal_nervous_system1.21285779
76MP0003448_altered_tumor_morphology1.18320167
77MP0003279_aneurysm1.18250301
78MP0002837_dystrophic_cardiac_calcinosis1.18170425
79MP0009745_abnormal_behavioral_response1.18104741
80MP0009046_muscle_twitch1.17390867
81MP0004510_myositis1.17178220
82MP0002693_abnormal_pancreas_physiology1.16658033
83MP0010307_abnormal_tumor_latency1.15950745
84MP0005310_abnormal_salivary_gland1.15694196
85MP0005389_reproductive_system_phenotype1.14945418
86MP0000465_gastrointestinal_hemorrhage1.13168175
87MP0002998_abnormal_bone_remodeling1.11217933
88MP0002019_abnormal_tumor_incidence1.11068161
89MP0008469_abnormal_protein_level1.08402054
90MP0003195_calcinosis1.07659070
91MP0002160_abnormal_reproductive_system1.07497700
92MP0005174_abnormal_tail_pigmentation1.05962765
93MP0000015_abnormal_ear_pigmentation1.03141101
94MP0010094_abnormal_chromosome_stability0.97856437
95MP0003646_muscle_fatigue0.95473025
96MP0001851_eye_inflammation0.94878116
97MP0004043_abnormal_pH_regulation0.92889368
98MP0004742_abnormal_vestibular_system0.91399704
99MP0005076_abnormal_cell_differentiation0.91115337
100MP0005058_abnormal_lysosome_morphology0.90040834
101MP0008875_abnormal_xenobiotic_pharmacok0.89521786
102MP0003693_abnormal_embryo_hatching0.89400943
103MP0001905_abnormal_dopamine_level0.86588209
104MP0005253_abnormal_eye_physiology0.86502350
105MP0000230_abnormal_systemic_arterial0.83649011
106MP0000343_altered_response_to0.83145456
107MP0008007_abnormal_cellular_replicative0.83033309
108MP0001664_abnormal_digestion0.82670903
109MP0002277_abnormal_respiratory_mucosa0.81210264
110MP0001919_abnormal_reproductive_system0.80909700
111MP0003091_abnormal_cell_migration0.80468004
112MP0003183_abnormal_peptide_metabolism0.79485841
113MP0005645_abnormal_hypothalamus_physiol0.79203525
114MP0003077_abnormal_cell_cycle0.79085847
115MP0002733_abnormal_thermal_nociception0.78968732
116MP0002095_abnormal_skin_pigmentation0.78628017
117MP0005023_abnormal_wound_healing0.78360597
118MP0005390_skeleton_phenotype0.77743740
119MP0008057_abnormal_DNA_replication0.76241309
120MP0002653_abnormal_ependyma_morphology0.75935928
121MP0005379_endocrine/exocrine_gland_phen0.75068024
122MP0002736_abnormal_nociception_after0.74670853
123MP0001958_emphysema0.74668718
124MP0005075_abnormal_melanosome_morpholog0.73913120
125MP0001970_abnormal_pain_threshold0.73541596
126MP0002735_abnormal_chemical_nociception0.73297481
127MP0001542_abnormal_bone_strength0.72296472
128MP0008961_abnormal_basal_metabolism0.71617832
129MP0003795_abnormal_bone_structure0.71223898
130MP0002136_abnormal_kidney_physiology0.68662407
131MP0005166_decreased_susceptibility_to0.67784681
132MP0008058_abnormal_DNA_repair0.66665548
133MP0008438_abnormal_cutaneous_collagen0.66492989
134MP0003045_fibrosis0.64260974
135MP0002132_abnormal_respiratory_system0.63256944
136MP0000249_abnormal_blood_vessel0.63214837
137MP0001243_abnormal_dermal_layer0.62957005
138MP0009764_decreased_sensitivity_to0.62244300
139MP0000313_abnormal_cell_death0.57247062
140MP0001915_intracranial_hemorrhage0.56300267
141MP0001663_abnormal_digestive_system0.53388987
142MP0000604_amyloidosis0.53335051
143MP0005621_abnormal_cell_physiology0.52610067
144MP0000569_abnormal_digit_pigmentation0.50257169
145MP0003111_abnormal_nucleus_morphology0.49796508
146MP0003566_abnormal_cell_adhesion0.47942197
147MP0001986_abnormal_taste_sensitivity0.46598756
148MP0009763_increased_sensitivity_to0.44546099
149MP0004957_abnormal_blastocyst_morpholog0.44062078
150MP0002009_preneoplasia0.44037368
151MP0003828_pulmonary_edema0.44003239

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)5.73437204
2B lymphocytopenia (HP:0010976)5.30446253
3Abnormality of B cell number (HP:0010975)5.30446253
4Cellulitis (HP:0100658)5.28140324
5Panhypogammaglobulinemia (HP:0003139)4.84741100
6Recurrent bronchitis (HP:0002837)4.84629876
7Thyroiditis (HP:0100646)4.82004927
8Recurrent viral infections (HP:0004429)4.65258118
9Severe combined immunodeficiency (HP:0004430)4.52530268
10Recurrent abscess formation (HP:0002722)4.50439189
11T lymphocytopenia (HP:0005403)4.47611364
12Papilloma (HP:0012740)4.41048679
13Verrucae (HP:0200043)4.41048679
14Recurrent fungal infections (HP:0002841)4.35167664
15Abnormality of T cell number (HP:0011839)4.25569577
16Eczematoid dermatitis (HP:0000976)4.17161619
17Meningitis (HP:0001287)4.15634482
18Combined immunodeficiency (HP:0005387)4.03451319
19Elevated erythrocyte sedimentation rate (HP:0003565)3.98074700
20Recurrent bacterial skin infections (HP:0005406)3.90474300
21IgM deficiency (HP:0002850)3.87605219
22Hypoplasia of the thymus (HP:0000778)3.78691701
23Chronic otitis media (HP:0000389)3.76769135
24IgG deficiency (HP:0004315)3.66675957
25Eosinophilia (HP:0001880)3.62132197
26Abnormality of T cells (HP:0002843)3.62014640
27Osteomyelitis (HP:0002754)3.59093699
28Congenital stationary night blindness (HP:0007642)3.46932413
29Pancreatic cysts (HP:0001737)3.46804745
30Myositis (HP:0100614)3.33928048
31Pancreatic fibrosis (HP:0100732)3.30535363
32Molar tooth sign on MRI (HP:0002419)3.20161197
33Abnormality of midbrain morphology (HP:0002418)3.20161197
34Chronic mucocutaneous candidiasis (HP:0002728)3.19417114
35Recurrent cutaneous fungal infections (HP:0011370)3.19417114
36Abnormality of eosinophils (HP:0001879)3.16988871
37Chronic sinusitis (HP:0011109)3.15706553
38Stomatitis (HP:0010280)3.14460297
39Nasal polyposis (HP:0100582)3.14240311
40Sepsis (HP:0100806)3.07408271
41Recurrent skin infections (HP:0001581)3.04810389
42Granulocytopenia (HP:0001913)3.04575402
43Recurrent sinusitis (HP:0011108)2.99670025
44Mediastinal lymphadenopathy (HP:0100721)2.99453689
45True hermaphroditism (HP:0010459)2.94448413
46Recurrent pneumonia (HP:0006532)2.87641532
47Congenital, generalized hypertrichosis (HP:0004540)2.83213478
48Inflammation of the large intestine (HP:0002037)2.82972083
49Lymphopenia (HP:0001888)2.82541076
50Bronchitis (HP:0012387)2.81528225
51Chronic hepatic failure (HP:0100626)2.80673900
52Leukocytosis (HP:0001974)2.78118061
53Thrombocytosis (HP:0001894)2.78115976
54Gastrointestinal inflammation (HP:0004386)2.75480382
55Abnormality of cells of the lymphoid lineage (HP:0012140)2.75289607
56Abnormality of T cell physiology (HP:0011840)2.73813271
573-Methylglutaconic aciduria (HP:0003535)2.71481336
58Abnormality of the nasal mucosa (HP:0000433)2.64561792
59Genetic anticipation (HP:0003743)2.63058343
60Hypoalbuminemia (HP:0003073)2.62586127
61Abnormal albumin level (HP:0012116)2.62586127
62Chronic obstructive pulmonary disease (HP:0006510)2.59087084
63Obstructive lung disease (HP:0006536)2.59087084
64Vasculitis (HP:0002633)2.58906133
65Autoimmune thrombocytopenia (HP:0001973)2.57192404
66Large for gestational age (HP:0001520)2.55182875
67Colitis (HP:0002583)2.54414844
68Recurrent lower respiratory tract infections (HP:0002783)2.53374873
69Nephronophthisis (HP:0000090)2.51603953
70Abnormality of the renal cortex (HP:0011035)2.50445148
71Hypoproteinemia (HP:0003075)2.48696555
72Gastrointestinal stroma tumor (HP:0100723)2.44784898
73Glucose intolerance (HP:0000833)2.44343104
74Absent rod-and cone-mediated responses on ERG (HP:0007688)2.42402134
75Pustule (HP:0200039)2.38602716
76Recurrent otitis media (HP:0000403)2.37273585
77Abnormal delayed hypersensitivity skin test (HP:0002963)2.35359230
78Abnormality of DNA repair (HP:0003254)2.33892981
79Interstitial pulmonary disease (HP:0006530)2.32051188
80Abnormal rod and cone electroretinograms (HP:0008323)2.27086256
81Abnormality of the pons (HP:0007361)2.25877405
82Tubular atrophy (HP:0000092)2.24195632
83Abnormality of alanine metabolism (HP:0010916)2.24060473
84Hyperalaninemia (HP:0003348)2.24060473
85Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.24060473
86Attenuation of retinal blood vessels (HP:0007843)2.21018411
87Increased IgM level (HP:0003496)2.20983818
88Increased density of long bones (HP:0006392)2.20959879
89IgA deficiency (HP:0002720)2.20874432
90Gaze-evoked nystagmus (HP:0000640)2.20164749
91Hypergammaglobulinemia (HP:0010702)2.19723056
92Type II lissencephaly (HP:0007260)2.19112399
93Abnormality of the renal medulla (HP:0100957)2.18298657
94Keratoconus (HP:0000563)2.17541954
95Increased corneal curvature (HP:0100692)2.17541954
96Lymphoma (HP:0002665)2.16317165
97Progressive cerebellar ataxia (HP:0002073)2.16229702
98Gingivitis (HP:0000230)2.15583897
99Mitral stenosis (HP:0001718)2.14142297
100Furrowed tongue (HP:0000221)2.14029372
101Skin ulcer (HP:0200042)2.10516525
102Small epiphyses (HP:0010585)2.05667537
103Cystic liver disease (HP:0006706)2.05185981
104Retrobulbar optic neuritis (HP:0100654)2.04560972
105Optic neuritis (HP:0100653)2.04560972
106Chronic diarrhea (HP:0002028)2.04470293
107Orchitis (HP:0100796)2.03964116
108Febrile seizures (HP:0002373)2.03492176
109Hypoplasia of the uterus (HP:0000013)2.03083921
110Skin rash (HP:0000988)2.02858031
111Abnormality of the prostate (HP:0008775)2.02699783
112Recurrent gram-negative bacterial infections (HP:0005420)2.02496463
113Abnormality of the fingertips (HP:0001211)1.99343204
114Sclerocornea (HP:0000647)1.97970015
115Periodontitis (HP:0000704)1.94788472
116Hypoplasia of the capital femoral epiphysis (HP:0003090)1.93669171
117Aplasia/Hypoplasia of the tibia (HP:0005772)1.93374307
118Decreased circulating renin level (HP:0003351)1.93114076
119Hematochezia (HP:0002573)1.92986862
120Cerebellar dysplasia (HP:0007033)1.92704182
121Renal cortical cysts (HP:0000803)1.92419603
122Hypoplasia of the pons (HP:0012110)1.90542881
123Abnormal number of erythroid precursors (HP:0012131)1.88443580
124Pulmonary infiltrates (HP:0002113)1.87935104
125Aplasia/hypoplasia of the uterus (HP:0008684)1.87686994
126Abnormality of macrophages (HP:0004311)1.87332867
127Prostate neoplasm (HP:0100787)1.86279807
128Impaired smooth pursuit (HP:0007772)1.84337483
129Abnormal glucose tolerance (HP:0001952)1.84290993
130Mitochondrial inheritance (HP:0001427)1.83937347
131Clubbing of toes (HP:0100760)1.83818783
132Disinhibition (HP:0000734)1.83519835
133Autoimmune hemolytic anemia (HP:0001890)1.82820809
134Hypothermia (HP:0002045)1.82190653
135Inability to walk (HP:0002540)1.81807755
136Arterial thrombosis (HP:0004420)1.81473938
137Aplasia/Hypoplasia of the thymus (HP:0010515)1.81313549
138Basal ganglia calcification (HP:0002135)1.81036203
139Abnormal drinking behavior (HP:0030082)1.79455924
140Polydipsia (HP:0001959)1.79455924
141Vertebral compression fractures (HP:0002953)1.79276780
142Emphysema (HP:0002097)1.78932417
143Hepatocellular necrosis (HP:0001404)1.77814609
144Hyperventilation (HP:0002883)1.77124584
145Aplasia/Hypoplasia of the tongue (HP:0010295)1.77057200
146Abolished electroretinogram (ERG) (HP:0000550)1.76199815
147Constricted visual fields (HP:0001133)1.75318212
148Neutropenia (HP:0001875)1.74666151
149Abnormality of the renal collecting system (HP:0004742)1.73447232
150Prolonged bleeding time (HP:0003010)1.71982717
151Stomach cancer (HP:0012126)1.71249988
152Hemoptysis (HP:0002105)1.70316063
153Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.70286044
154Flattened epiphyses (HP:0003071)1.69071460
155Restrictive lung disease (HP:0002091)1.66985237
156Encephalitis (HP:0002383)1.65400687
157Increased IgE level (HP:0003212)1.63807812
158Petechiae (HP:0000967)1.61936807
159Entropion (HP:0000621)1.59252598
160Spinal cord lesions (HP:0100561)1.58243498

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K104.78782536
2MAP4K14.49353896
3TXK3.30841205
4TAOK33.01139676
5CAMKK23.01060020
6EEF2K2.94958088
7BLK2.86344058
8ZAP702.79308204
9RIPK42.78860177
10ERN12.24130064
11JAK32.16919625
12SYK2.16569878
13GRK62.13392623
14TESK22.12830043
15GRK12.06671782
16PINK12.02716500
17STK102.02171160
18TBK11.89958152
19IKBKE1.83866856
20EIF2AK31.80113850
21BTK1.78792993
22TESK11.78661253
23TYK21.77508075
24MAP3K121.71010686
25MAP4K21.70400148
26NUAK11.70014131
27CSF1R1.68726067
28TEC1.63351662
29KIT1.63308696
30GRK71.61410733
31LCK1.59622410
32WNK41.58790867
33MAP3K141.52528957
34HCK1.51545736
35ACVR1B1.49652071
36ITK1.44238325
37DAPK21.43974209
38TLK11.37868789
39CAMKK11.37615121
40SIK21.37077616
41FES1.36393727
42TRIB31.34479323
43NME21.33991992
44PTK2B1.33468921
45INSRR1.30931491
46LYN1.30458129
47JAK11.30151358
48LRRK21.28662189
49KDR1.27225708
50BMPR1B1.25938670
51ADRBK11.23382940
52NLK1.23228599
53PIM11.22333867
54PIM21.19425454
55FGFR31.19394870
56SIK31.18918911
57STK391.18405439
58BMPR21.17987876
59TGFBR21.16259563
60MUSK1.11280011
61MAP2K21.10317982
62VRK21.10262875
63CSK1.08289412
64BRSK21.04700668
65GRK51.02635049
66PKN21.02190427
67FGFR40.99559308
68SCYL20.99046943
69IKBKB0.98813370
70STK40.96478151
71MAPK130.93389712
72PASK0.93180913
73MAP2K60.89866720
74OXSR10.89855763
75MARK30.89095997
76IRAK40.89046102
77PDK30.84338905
78PDK40.84338905
79RPS6KA40.84227594
80PIK3CG0.81558957
81PAK30.78853890
82RPS6KA50.75940797
83CLK10.75610080
84FLT30.73534847
85DAPK10.72641683
86NEK20.67517846
87MAPK70.66712563
88CDK40.66264557
89MAPK40.64359018
90PAK60.63633306
91RPS6KB20.62929353
92MST40.62671117
93IRAK10.60971464
94TRPM70.59752565
95EIF2AK10.59684589
96AKT30.58797988
97MAPKAPK30.57699735
98TNK20.54604833
99PDK10.53091360
100NEK90.51621779
101TNIK0.51575250
102MAP3K130.48754997
103EPHA30.48612331
104YES10.48217847
105EPHB10.46105233
106PRKCQ0.44212939
107MAP3K80.44202486
108ILK0.44003037
109BCKDK0.40410627
110DYRK1B0.39442675
111TGFBR10.39423693
112MAPK110.38933256
113PRKCE0.38678016
114FRK0.37995143
115HIPK20.37900391
116FYN0.37872255
117IGF1R0.37622732
118MAP3K110.37186417
119BUB10.37182930
120JAK20.36627412
121ABL10.36294415
122VRK10.36216009
123MATK0.35734961
124MAP3K40.35005516
125PRKD20.34843257
126CHUK0.34626343
127MAPK120.34496743
128PRKCD0.33745640
129MAPKAPK20.33682678
130WNK30.33681801
131SIK10.33154644
132CDK60.32236579
133LIMK10.31958598
134ZAK0.30790614
135PAK40.30731511
136CDK30.30148589
137CHEK20.29653937
138INSR0.29632176
139MELK0.29056618
140PRKCH0.28989871
141ADRBK20.28915206
142EIF2AK20.28704648
143STK240.28348408
144EGFR0.27473719
145CDK90.26776738
146PDK20.26276921
147ATR0.25603134
148PDGFRB0.25247818

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.71275853
2B cell receptor signaling pathway_Homo sapiens_hsa046622.54771027
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.28336281
4Measles_Homo sapiens_hsa051622.20249318
5Leishmaniasis_Homo sapiens_hsa051402.16677395
6Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.13277929
7Intestinal immune network for IgA production_Homo sapiens_hsa046722.04853099
8Osteoclast differentiation_Homo sapiens_hsa043802.01696784
9T cell receptor signaling pathway_Homo sapiens_hsa046601.97045584
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.90180340
11Hematopoietic cell lineage_Homo sapiens_hsa046401.88356688
12Antigen processing and presentation_Homo sapiens_hsa046121.86968392
13Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.78312913
14RNA polymerase_Homo sapiens_hsa030201.74861012
15Non-homologous end-joining_Homo sapiens_hsa034501.65056099
16Allograft rejection_Homo sapiens_hsa053301.57105758
17Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.56323705
18Phototransduction_Homo sapiens_hsa047441.56238343
19Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.54235742
20Legionellosis_Homo sapiens_hsa051341.50975068
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.49618575
22Tuberculosis_Homo sapiens_hsa051521.49269179
23Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.45589671
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.41856619
25Toll-like receptor signaling pathway_Homo sapiens_hsa046201.41384181
26Shigellosis_Homo sapiens_hsa051311.40764900
27Maturity onset diabetes of the young_Homo sapiens_hsa049501.40703817
28Selenocompound metabolism_Homo sapiens_hsa004501.37935363
29Systemic lupus erythematosus_Homo sapiens_hsa053221.36258405
30Herpes simplex infection_Homo sapiens_hsa051681.35613410
31Graft-versus-host disease_Homo sapiens_hsa053321.35142463
32Fanconi anemia pathway_Homo sapiens_hsa034601.32839069
33Linoleic acid metabolism_Homo sapiens_hsa005911.30303433
34Hepatitis B_Homo sapiens_hsa051611.28498372
35Malaria_Homo sapiens_hsa051441.27618275
36Toxoplasmosis_Homo sapiens_hsa051451.26371163
37Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.26265086
38NOD-like receptor signaling pathway_Homo sapiens_hsa046211.24804199
39Viral carcinogenesis_Homo sapiens_hsa052031.22001805
40Jak-STAT signaling pathway_Homo sapiens_hsa046301.21613008
41Influenza A_Homo sapiens_hsa051641.20692559
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.20391457
43Salmonella infection_Homo sapiens_hsa051321.20065568
44Ribosome_Homo sapiens_hsa030101.19723499
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.18930492
46Apoptosis_Homo sapiens_hsa042101.14424169
47Taste transduction_Homo sapiens_hsa047421.13368289
48Chemokine signaling pathway_Homo sapiens_hsa040621.11503544
49TNF signaling pathway_Homo sapiens_hsa046681.10328362
50Acute myeloid leukemia_Homo sapiens_hsa052211.09997409
51Asthma_Homo sapiens_hsa053101.08669935
52Pancreatic cancer_Homo sapiens_hsa052121.08073244
53Pyrimidine metabolism_Homo sapiens_hsa002401.07626152
54Nicotine addiction_Homo sapiens_hsa050331.06464499
55Salivary secretion_Homo sapiens_hsa049701.06327588
56DNA replication_Homo sapiens_hsa030301.05862320
57Pertussis_Homo sapiens_hsa051331.05804551
58Base excision repair_Homo sapiens_hsa034101.05488451
59Morphine addiction_Homo sapiens_hsa050321.04997302
60alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.04602942
61Leukocyte transendothelial migration_Homo sapiens_hsa046701.03404917
62Viral myocarditis_Homo sapiens_hsa054161.02888661
63Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.02659197
64Epstein-Barr virus infection_Homo sapiens_hsa051691.00976843
65Type I diabetes mellitus_Homo sapiens_hsa049401.00011545
66Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.98927475
67Chronic myeloid leukemia_Homo sapiens_hsa052200.98791301
68Rheumatoid arthritis_Homo sapiens_hsa053230.97817135
69Nitrogen metabolism_Homo sapiens_hsa009100.97317308
70Protein export_Homo sapiens_hsa030600.96759798
71One carbon pool by folate_Homo sapiens_hsa006700.96675049
72RNA degradation_Homo sapiens_hsa030180.96444589
73Basal transcription factors_Homo sapiens_hsa030220.95038656
74Transcriptional misregulation in cancer_Homo sapiens_hsa052020.94614993
75Purine metabolism_Homo sapiens_hsa002300.94478987
76AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.92421346
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.92109738
78Platelet activation_Homo sapiens_hsa046110.91440243
79Oxidative phosphorylation_Homo sapiens_hsa001900.89853117
80Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.88708480
81Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.88639791
82HTLV-I infection_Homo sapiens_hsa051660.84258793
83p53 signaling pathway_Homo sapiens_hsa041150.84010666
84Other glycan degradation_Homo sapiens_hsa005110.78724323
85Neurotrophin signaling pathway_Homo sapiens_hsa047220.78226173
86Colorectal cancer_Homo sapiens_hsa052100.76076404
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75908204
88Tryptophan metabolism_Homo sapiens_hsa003800.75874700
89Glycosaminoglycan degradation_Homo sapiens_hsa005310.75317719
90Phagosome_Homo sapiens_hsa041450.75226546
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.72947776
92Calcium signaling pathway_Homo sapiens_hsa040200.71209649
93Ether lipid metabolism_Homo sapiens_hsa005650.70719394
94Non-small cell lung cancer_Homo sapiens_hsa052230.69914012
95Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.69389597
96Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.68178939
97VEGF signaling pathway_Homo sapiens_hsa043700.67753679
98Olfactory transduction_Homo sapiens_hsa047400.67605079
99Autoimmune thyroid disease_Homo sapiens_hsa053200.67532153
100Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.65165848
101Parkinsons disease_Homo sapiens_hsa050120.64530948
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64152394
103Proteasome_Homo sapiens_hsa030500.62116611
104N-Glycan biosynthesis_Homo sapiens_hsa005100.60244749
105Cell cycle_Homo sapiens_hsa041100.59916123
106Alcoholism_Homo sapiens_hsa050340.59761564
107Renin secretion_Homo sapiens_hsa049240.58309921
108African trypanosomiasis_Homo sapiens_hsa051430.57157976
109Phosphatidylinositol signaling system_Homo sapiens_hsa040700.56557145
110Mismatch repair_Homo sapiens_hsa034300.55330954
111HIF-1 signaling pathway_Homo sapiens_hsa040660.55294559
112Circadian entrainment_Homo sapiens_hsa047130.54552587
113ABC transporters_Homo sapiens_hsa020100.54543991
114Insulin secretion_Homo sapiens_hsa049110.54507423
115Small cell lung cancer_Homo sapiens_hsa052220.53791431
116Spliceosome_Homo sapiens_hsa030400.53771676
117Alzheimers disease_Homo sapiens_hsa050100.53260832
118Glycerolipid metabolism_Homo sapiens_hsa005610.52122073
119Long-term depression_Homo sapiens_hsa047300.52063336
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.51786501
121Homologous recombination_Homo sapiens_hsa034400.51639463
122MAPK signaling pathway_Homo sapiens_hsa040100.51073857
123Pentose phosphate pathway_Homo sapiens_hsa000300.50618456
124Endocytosis_Homo sapiens_hsa041440.49136727
125Renin-angiotensin system_Homo sapiens_hsa046140.48842698
126Lysosome_Homo sapiens_hsa041420.48615832
127Serotonergic synapse_Homo sapiens_hsa047260.48525410
128Regulation of autophagy_Homo sapiens_hsa041400.48316092
129Hepatitis C_Homo sapiens_hsa051600.48064414
130Glioma_Homo sapiens_hsa052140.46792266
131Amphetamine addiction_Homo sapiens_hsa050310.46731335
132Steroid hormone biosynthesis_Homo sapiens_hsa001400.45253633
133Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44836465
134Cholinergic synapse_Homo sapiens_hsa047250.44161401
135Staphylococcus aureus infection_Homo sapiens_hsa051500.43895620
136Prolactin signaling pathway_Homo sapiens_hsa049170.43609171
137Caffeine metabolism_Homo sapiens_hsa002320.43393139
138Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.43212069
139Butanoate metabolism_Homo sapiens_hsa006500.43182392
140Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42318636
141Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.42258495
142Oxytocin signaling pathway_Homo sapiens_hsa049210.41937969
143Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.41769764
144SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41006640
145FoxO signaling pathway_Homo sapiens_hsa040680.39771995
146Glutamatergic synapse_Homo sapiens_hsa047240.37073836
147Huntingtons disease_Homo sapiens_hsa050160.36725404
148Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36374468
149Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.35716307
150Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33717301
151mTOR signaling pathway_Homo sapiens_hsa041500.33591887
152Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.33295835
153Inositol phosphate metabolism_Homo sapiens_hsa005620.32860252
154Nucleotide excision repair_Homo sapiens_hsa034200.31444218

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