STAP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive thymic T cell selection (GO:0045059)5.52393229
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.43196194
3regulation of B cell receptor signaling pathway (GO:0050855)4.66061023
4positive regulation of gamma-delta T cell activation (GO:0046645)4.65674029
5positive T cell selection (GO:0043368)4.49477052
6negative thymic T cell selection (GO:0045060)4.40203947
7antigen processing and presentation of endogenous antigen (GO:0019883)4.36245642
8cellular response to interleukin-15 (GO:0071350)4.26457057
9response to interleukin-15 (GO:0070672)4.18685323
10antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.17539773
11antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.17539773
12negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.11400315
13negative regulation of cell killing (GO:0031342)4.11400315
14thymic T cell selection (GO:0045061)4.06122404
15negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.99389501
16positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.90712987
17immunoglobulin mediated immune response (GO:0016064)3.90015234
18positive regulation of B cell differentiation (GO:0045579)3.89214176
19neutrophil activation involved in immune response (GO:0002283)3.83962643
20positive regulation by symbiont of host defense response (GO:0052509)3.77406344
21modulation by symbiont of host defense response (GO:0052031)3.77406344
22modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.77406344
23modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.77406344
24positive regulation by organism of defense response of other organism involved in symbiotic interact3.77406344
25modulation by symbiont of host immune response (GO:0052553)3.77406344
26mast cell activation (GO:0045576)3.77158853
27response to peptidoglycan (GO:0032494)3.75112153
28T cell selection (GO:0045058)3.67706615
29regulation of RIG-I signaling pathway (GO:0039535)3.66474947
30B cell receptor signaling pathway (GO:0050853)3.66099998
31regulation of B cell differentiation (GO:0045577)3.63660804
32ribosomal small subunit assembly (GO:0000028)3.63155856
33positive regulation of alpha-beta T cell proliferation (GO:0046641)3.62956731
34defense response to protozoan (GO:0042832)3.62508136
35positive regulation of type 2 immune response (GO:0002830)3.62119461
36regulation of interferon-beta biosynthetic process (GO:0045357)3.56409051
37negative regulation of T cell mediated immunity (GO:0002710)3.54008534
38leukocyte aggregation (GO:0070486)3.52982765
39chaperone mediated protein folding requiring cofactor (GO:0051085)3.51967323
40mature B cell differentiation (GO:0002335)3.49279122
41response to interferon-beta (GO:0035456)3.48222338
42antigen receptor-mediated signaling pathway (GO:0050851)3.43362704
43B cell proliferation (GO:0042100)3.42523868
44regulation of germinal center formation (GO:0002634)3.41883186
45regulation of dendritic cell antigen processing and presentation (GO:0002604)3.41699108
46regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.38642670
47positive regulation of interferon-alpha production (GO:0032727)3.34969613
48respiratory burst (GO:0045730)3.32574375
49negative regulation of T-helper cell differentiation (GO:0045623)3.32132473
50negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.32132473
51regulation of natural killer cell mediated immunity (GO:0002715)3.31233653
52regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.31233653
53response to protozoan (GO:0001562)3.30090197
54cellular response to type I interferon (GO:0071357)3.30021659
55type I interferon signaling pathway (GO:0060337)3.30021659
56response to type I interferon (GO:0034340)3.29703504
57cellular response to interferon-beta (GO:0035458)3.27217283
58myeloid dendritic cell activation (GO:0001773)3.23574546
59regulation of T-helper 1 cell differentiation (GO:0045625)3.20883439
60negative regulation of lymphocyte mediated immunity (GO:0002707)3.20604128
61regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.20413198
62interferon-gamma production (GO:0032609)3.20086488
63regulation of interferon-alpha production (GO:0032647)3.19788687
64positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.19572223
65mature B cell differentiation involved in immune response (GO:0002313)3.19033447
66positive regulation of granulocyte differentiation (GO:0030854)3.17558386
67regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.17200548
68regulation of B cell proliferation (GO:0030888)3.16592432
69CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.14145160
70positive regulation of T cell cytokine production (GO:0002726)3.12851699
71regulation of leukocyte mediated cytotoxicity (GO:0001910)3.10632321
72response to interferon-alpha (GO:0035455)3.10211591
73B cell mediated immunity (GO:0019724)3.09061270
74T cell costimulation (GO:0031295)3.08108975
75neutrophil activation (GO:0042119)3.07806408
76pyrimidine ribonucleoside catabolic process (GO:0046133)3.07693170
77positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)3.07220295
78positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.06582989
79Arp2/3 complex-mediated actin nucleation (GO:0034314)3.06250646
80positive regulation of defense response to virus by host (GO:0002230)3.05480590
81negative regulation of phagocytosis (GO:0050765)3.04647360
82regulation of cell killing (GO:0031341)3.04568617
83lymphocyte costimulation (GO:0031294)3.03574295
84cytidine metabolic process (GO:0046087)3.03299322
85cytidine catabolic process (GO:0006216)3.03299322
86cytidine deamination (GO:0009972)3.03299322
87regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)3.03098467
88myeloid cell activation involved in immune response (GO:0002275)3.03059038
89positive regulation of cell killing (GO:0031343)3.02026592
90positive regulation of antigen processing and presentation (GO:0002579)3.02005136
91response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.00505643
92response to host immune response (GO:0052572)3.00505643
93negative regulation of alpha-beta T cell activation (GO:0046636)3.00398964
94regulation of gamma-delta T cell activation (GO:0046643)2.97794398
95regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.96558206
96cellular response to zinc ion (GO:0071294)2.96464481
97germinal center formation (GO:0002467)2.95634827
98regulation of T cell receptor signaling pathway (GO:0050856)2.95395791
99negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.94770066
100regulation of interleukin-12 biosynthetic process (GO:0045075)2.94697422
101regulation of mast cell activation (GO:0033003)2.93491675
102positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.92500288
103mast cell activation involved in immune response (GO:0002279)2.92163197
104mast cell degranulation (GO:0043303)2.92163197
105interferon-gamma-mediated signaling pathway (GO:0060333)2.91716448
106regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.91500805
107leukocyte degranulation (GO:0043299)2.90686765
108T cell homeostasis (GO:0043029)2.90680450
109positive regulation of natural killer cell mediated immunity (GO:0002717)2.89446383
110granulocyte activation (GO:0036230)2.88971842
111regulation of gamma-delta T cell differentiation (GO:0045586)2.87127686
112negative regulation of leukocyte mediated immunity (GO:0002704)2.86839593
113regulation of T-helper 1 type immune response (GO:0002825)2.86286383
114regulation of B cell activation (GO:0050864)2.85399938
115positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.84081301
116positive regulation of interferon-beta production (GO:0032728)2.83562335
117myeloid dendritic cell differentiation (GO:0043011)2.82922949
118DNA deamination (GO:0045006)2.82216160
119negative regulation of adaptive immune response (GO:0002820)2.81845183
120negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.81829628
121positive regulation of immunoglobulin production (GO:0002639)2.81208565
122neutrophil mediated immunity (GO:0002446)2.81060437
123negative regulation of viral genome replication (GO:0045071)2.81011206
124positive regulation of macrophage differentiation (GO:0045651)2.79198881
125superoxide anion generation (GO:0042554)2.77638276
126regulation of B cell apoptotic process (GO:0002902)2.77038331
127B cell homeostasis (GO:0001782)2.75893480
128positive regulation of T cell mediated cytotoxicity (GO:0001916)2.75619350
129response to muramyl dipeptide (GO:0032495)2.71211246
130lymphocyte homeostasis (GO:0002260)2.71077800
131T cell migration (GO:0072678)2.70741650
132lymph node development (GO:0048535)2.68701408
133definitive hemopoiesis (GO:0060216)2.66854459
134response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.66067678
135response to host (GO:0075136)2.66067678
136response to host defenses (GO:0052200)2.66067678
137regulation of antigen processing and presentation (GO:0002577)2.65193829
138macrophage activation involved in immune response (GO:0002281)2.64922908
139production of molecular mediator involved in inflammatory response (GO:0002532)2.64639483
140cellular response to exogenous dsRNA (GO:0071360)2.64012468
141megakaryocyte development (GO:0035855)2.61908797
142NIK/NF-kappaB signaling (GO:0038061)2.61010019
143platelet dense granule organization (GO:0060155)2.60755683
144lymphoid progenitor cell differentiation (GO:0002320)2.60609875
145myeloid leukocyte activation (GO:0002274)2.59578450
146regulation of T cell mediated cytotoxicity (GO:0001914)2.59440447
147regulation of mast cell degranulation (GO:0043304)2.58099329
148detection of other organism (GO:0098543)2.57870793
149regulation of alpha-beta T cell proliferation (GO:0046640)2.57827053
150positive regulation of B cell activation (GO:0050871)2.57740672
151I-kappaB kinase/NF-kappaB signaling (GO:0007249)2.57667173
152telomere maintenance via semi-conservative replication (GO:0032201)2.56188951
153positive regulation of B cell proliferation (GO:0030890)2.55798598
154negative T cell selection (GO:0043383)2.54257164
155T-helper 1 type immune response (GO:0042088)2.54249622
156B cell activation (GO:0042113)2.52998190

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.71798572
2E2F7_22180533_ChIP-Seq_HELA_Human4.68008649
3IRF8_21731497_ChIP-ChIP_J774_Mouse4.47665528
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.41309051
5BP1_19119308_ChIP-ChIP_Hs578T_Human4.02009404
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.01758677
7* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.72242215
8SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.48286977
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.32423297
10SCL_19346495_ChIP-Seq_HPC-7_Human3.27921918
11IRF8_27001747_Chip-Seq_BMDM_Mouse3.05768956
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.01164249
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.97580605
14* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.75814384
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.75438554
16STAT4_19710469_ChIP-ChIP_TH1__Mouse2.71491035
17* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.62133015
18* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.58804969
19FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.58653471
20* SPI1_23547873_ChIP-Seq_NB4_Human2.53196275
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.45162467
22STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.44543819
23MYB_26560356_Chip-Seq_TH2_Human2.18866730
24NOTCH1_21737748_ChIP-Seq_TLL_Human2.12171375
25ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.08981978
26FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.04693870
27MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.02424787
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.97870161
29LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.97702555
30HOXB4_20404135_ChIP-ChIP_EML_Mouse1.96439948
31SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.94924012
32RUNX_20019798_ChIP-Seq_JUKART_Human1.90882201
33RUNX1_22412390_ChIP-Seq_EML_Mouse1.89863655
34VDR_21846776_ChIP-Seq_THP-1_Human1.89748783
35MYB_26560356_Chip-Seq_TH1_Human1.86511750
36VDR_24763502_ChIP-Seq_THP-1_Human1.85255078
37* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.82440782
38LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.81761179
39MAF_26560356_Chip-Seq_TH1_Human1.80243804
40EGR1_19374776_ChIP-ChIP_THP-1_Human1.76500759
41FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.75946996
42MYC_22102868_ChIP-Seq_BL_Human1.74450181
43BRD4_27068464_Chip-Seq_AML-cells_Mouse1.69029081
44ERG_20887958_ChIP-Seq_HPC-7_Mouse1.68206991
45E2F4_17652178_ChIP-ChIP_JURKAT_Human1.65702986
46CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.60839230
47Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.59108968
48HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.57503431
49PU_27001747_Chip-Seq_BMDM_Mouse1.54579167
50GATA2_22383799_ChIP-Seq_G1ME_Mouse1.51289462
51* VDR_23849224_ChIP-Seq_CD4+_Human1.51265213
52GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.48016295
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.42217870
54UTX_26944678_Chip-Seq_JUKART_Human1.41946137
55NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.38296344
56MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.38192204
57FOXP3_21729870_ChIP-Seq_TREG_Human1.37009673
58GATA1_22025678_ChIP-Seq_K562_Human1.36392907
59GABP_17652178_ChIP-ChIP_JURKAT_Human1.35720541
60RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.35280047
61SPI1_23127762_ChIP-Seq_K562_Human1.32018977
62GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.31898654
63ELK1_19687146_ChIP-ChIP_HELA_Human1.30772726
64NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.29650796
65E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.28402783
66EST1_17652178_ChIP-ChIP_JURKAT_Human1.28399003
67CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.25822250
68IRF1_19129219_ChIP-ChIP_H3396_Human1.24369509
69GATA1_22383799_ChIP-Seq_G1ME_Mouse1.23458409
70CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.23076603
71VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.22658417
72NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.17237267
73FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.17105251
74VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.17077002
75CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15923887
76MAF_26560356_Chip-Seq_TH2_Human1.13696948
77JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.12154600
78STAT6_21828071_ChIP-Seq_BEAS2B_Human1.10712471
79KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.09882277
80* GATA3_27048872_Chip-Seq_THYMUS_Human1.07910373
81PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06902378
82SRF_21415370_ChIP-Seq_HL-1_Mouse1.06306752
83CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06238225
84PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05125503
85BCL6_27268052_Chip-Seq_Bcells_Human1.04890310
86STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.04466722
87FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02097977
88CIITA_25753668_ChIP-Seq_RAJI_Human1.01227213
89SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01127591
90TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00559564
91MYC_18555785_ChIP-Seq_MESCs_Mouse1.00542096
92GATA3_26560356_Chip-Seq_TH2_Human1.00060599
93CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99731264
94HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.99361523
95PU.1_20513432_ChIP-Seq_Bcells_Mouse0.98466769
96P300_27268052_Chip-Seq_Bcells_Human0.98410352
97PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97319046
98CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.96198500
99RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.96092202
100EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.96025871
101FLI1_27457419_Chip-Seq_LIVER_Mouse0.94872925
102SMRT_27268052_Chip-Seq_Bcells_Human0.92644422
103HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.91034041
104FOXM1_23109430_ChIP-Seq_U2OS_Human0.90403612
105KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.89902097
106PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.89436219
107TCF7_22412390_ChIP-Seq_EML_Mouse0.87496002
108TFEB_21752829_ChIP-Seq_HELA_Human0.85695985
109BCOR_27268052_Chip-Seq_Bcells_Human0.85432882
110ELF1_20517297_ChIP-Seq_JURKAT_Human0.85290739
111E2F1_21310950_ChIP-Seq_MCF-7_Human0.84909141
112STAT1_20625510_ChIP-Seq_HELA_Human0.84597319
113ETS1_22383799_ChIP-Seq_G1ME_Mouse0.82133476
114MYC_18358816_ChIP-ChIP_MESCs_Mouse0.81881978
115CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.80160851
116TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.79494231
117GATA1_19941827_ChIP-Seq_MEL_Mouse0.79340009
118GATA3_26560356_Chip-Seq_TH1_Human0.78663742
119VDR_24787735_ChIP-Seq_THP-1_Human0.78314610
120GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78109842
121RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.75408191
122EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.75328967
123SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.74234852

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.57455814
2MP0009785_altered_susceptibility_to3.38119264
3MP0005671_abnormal_response_to3.25209854
4MP0001800_abnormal_humoral_immune3.05874403
5MP0002138_abnormal_hepatobiliary_system2.98023125
6MP0002148_abnormal_hypersensitivity_rea2.90819383
7MP0005000_abnormal_immune_tolerance2.90196653
8MP0003436_decreased_susceptibility_to2.85996435
9MP0000685_abnormal_immune_system2.83090109
10MP0002452_abnormal_antigen_presenting2.79976999
11MP0005387_immune_system_phenotype2.78681222
12MP0001790_abnormal_immune_system2.78681222
13MP0005025_abnormal_response_to2.78268849
14MP0002419_abnormal_innate_immunity2.65421377
15MP0003763_abnormal_thymus_physiology2.65048879
16MP0002723_abnormal_immune_serum2.64261247
17MP0002420_abnormal_adaptive_immunity2.57217305
18MP0001819_abnormal_immune_cell2.55014414
19MP0003724_increased_susceptibility_to2.43957006
20MP0005174_abnormal_tail_pigmentation2.43805468
21MP0002396_abnormal_hematopoietic_system2.39531626
22MP0002398_abnormal_bone_marrow2.28197807
23MP0005464_abnormal_platelet_physiology2.24009890
24MP0002166_altered_tumor_susceptibility2.20123734
25MP0000716_abnormal_immune_system2.08308585
26MP0001853_heart_inflammation1.99430866
27MP0002405_respiratory_system_inflammati1.99339797
28MP0000689_abnormal_spleen_morphology1.99053862
29MP0003303_peritoneal_inflammation1.97473323
30MP0002006_tumorigenesis1.96182738
31MP0002132_abnormal_respiratory_system1.95472506
32MP0002722_abnormal_immune_system1.79874871
33MP0002429_abnormal_blood_cell1.74995730
34MP0000015_abnormal_ear_pigmentation1.72737673
35MP0004808_abnormal_hematopoietic_stem1.72444647
36MP0009333_abnormal_splenocyte_physiolog1.69443474
37MP0010155_abnormal_intestine_physiology1.69329968
38MP0003300_gastrointestinal_ulcer1.68061044
39MP0000465_gastrointestinal_hemorrhage1.66989286
40MP0001845_abnormal_inflammatory_respons1.66549975
41MP0001545_abnormal_hematopoietic_system1.66308349
42MP0005397_hematopoietic_system_phenotyp1.66308349
43MP0005075_abnormal_melanosome_morpholog1.65956551
44MP0006082_CNS_inflammation1.62516974
45MP0002277_abnormal_respiratory_mucosa1.61460817
46MP0000372_irregular_coat_pigmentation1.50706423
47MP0001873_stomach_inflammation1.44894105
48MP0002933_joint_inflammation1.43708884
49MP0000490_abnormal_crypts_of1.42759751
50MP0002095_abnormal_skin_pigmentation1.40147803
51MP0003866_abnormal_defecation1.39845979
52MP0000703_abnormal_thymus_morphology1.38737371
53MP0008469_abnormal_protein_level1.36090808
54MP0000371_diluted_coat_color1.34551038
55MP0009697_abnormal_copulation1.31237986
56MP0001986_abnormal_taste_sensitivity1.28684531
57MP0009764_decreased_sensitivity_to1.28638961
58MP0004510_myositis1.25782231
59MP0002163_abnormal_gland_morphology1.23016234
60MP0004947_skin_inflammation1.21440052
61MP0009278_abnormal_bone_marrow1.19477615
62MP0001533_abnormal_skeleton_physiology1.19061678
63MP0005310_abnormal_salivary_gland1.19011741
64MP0008057_abnormal_DNA_replication1.18884492
65MP0008058_abnormal_DNA_repair1.12188626
66MP0003183_abnormal_peptide_metabolism1.11073184
67MP0000569_abnormal_digit_pigmentation1.10323448
68MP0000858_altered_metastatic_potential1.08933688
69MP0005409_darkened_coat_color1.08724615
70MP0010094_abnormal_chromosome_stability1.07872017
71MP0006292_abnormal_olfactory_placode1.04054878
72MP0003693_abnormal_embryo_hatching1.03511862
73MP0002009_preneoplasia1.03237758
74MP0003448_altered_tumor_morphology1.02959078
75MP0008007_abnormal_cellular_replicative1.01484360
76MP0004381_abnormal_hair_follicle0.98791368
77MP0002075_abnormal_coat/hair_pigmentati0.97839007
78MP0000343_altered_response_to0.96225243
79MP0003172_abnormal_lysosome_physiology0.87501864
80MP0002019_abnormal_tumor_incidence0.86676174
81MP0001663_abnormal_digestive_system0.85614491
82MP0005379_endocrine/exocrine_gland_phen0.85032955
83MP0001186_pigmentation_phenotype0.83671174
84MP0003806_abnormal_nucleotide_metabolis0.83501184
85MP0005058_abnormal_lysosome_morphology0.82155939
86MP0005171_absent_coat_pigmentation0.81540733
87MP0003828_pulmonary_edema0.81155114
88MP0008260_abnormal_autophagy0.78887454
89MP0000681_abnormal_thyroid_gland0.77013921
90MP0001188_hyperpigmentation0.76144027
91MP0003077_abnormal_cell_cycle0.75381292
92MP0003191_abnormal_cellular_cholesterol0.74209379
93MP0009763_increased_sensitivity_to0.74131456
94MP0003045_fibrosis0.73344181
95MP0002136_abnormal_kidney_physiology0.70493155
96MP0003252_abnormal_bile_duct0.70437963
97MP0004782_abnormal_surfactant_physiolog0.70042257
98MP0003656_abnormal_erythrocyte_physiolo0.68323631
99MP0002928_abnormal_bile_duct0.67047487
100MP0003186_abnormal_redox_activity0.66072752
101MP0008877_abnormal_DNA_methylation0.65392956
102MP0002998_abnormal_bone_remodeling0.64809185
103MP0005645_abnormal_hypothalamus_physiol0.64776050
104MP0006036_abnormal_mitochondrial_physio0.64718128
105MP0002693_abnormal_pancreas_physiology0.63584410
106MP0003136_yellow_coat_color0.62148462
107MP0000313_abnormal_cell_death0.57536783
108MP0009765_abnormal_xenobiotic_induced0.57386085
109MP0001851_eye_inflammation0.57309468
110MP0005390_skeleton_phenotype0.57214907
111MP0005408_hypopigmentation0.56470836
112MP0005166_decreased_susceptibility_to0.56454269
113MP0000609_abnormal_liver_physiology0.54674804
114MP0000249_abnormal_blood_vessel0.54626566
115MP0010307_abnormal_tumor_latency0.53919436
116MP0001881_abnormal_mammary_gland0.53098074
117MP0002083_premature_death0.47907932
118MP0002876_abnormal_thyroid_physiology0.45734608
119MP0008874_decreased_physiological_sensi0.45274346
120MP0001764_abnormal_homeostasis0.44534379
121MP0009643_abnormal_urine_homeostasis0.42770941
122MP0003786_premature_aging0.42745501

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.33626780
2Recurrent bacterial skin infections (HP:0005406)4.71922274
3Eczematoid dermatitis (HP:0000976)4.39833301
4Myositis (HP:0100614)4.15663239
5Elevated erythrocyte sedimentation rate (HP:0003565)4.13607695
6Recurrent fungal infections (HP:0002841)3.64315691
7IgM deficiency (HP:0002850)3.63072254
8Mediastinal lymphadenopathy (HP:0100721)3.60414701
9Thrombocytosis (HP:0001894)3.60331896
10Verrucae (HP:0200043)3.57683680
11Papilloma (HP:0012740)3.57683680
12Recurrent viral infections (HP:0004429)3.52029686
13Meningitis (HP:0001287)3.50968833
14Panhypogammaglobulinemia (HP:0003139)3.46819238
15Agammaglobulinemia (HP:0004432)3.43238683
16Recurrent skin infections (HP:0001581)3.40436510
17Chronic mucocutaneous candidiasis (HP:0002728)3.33705953
18Recurrent cutaneous fungal infections (HP:0011370)3.33705953
19Chronic obstructive pulmonary disease (HP:0006510)3.30185614
20Obstructive lung disease (HP:0006536)3.30185614
21Optic neuritis (HP:0100653)3.28610140
22Retrobulbar optic neuritis (HP:0100654)3.28610140
23Vasculitis (HP:0002633)3.28319244
24Spontaneous hematomas (HP:0007420)3.22790876
25Abnormal delayed hypersensitivity skin test (HP:0002963)3.20343728
26Orchitis (HP:0100796)3.20094644
27Stomatitis (HP:0010280)3.15570273
28Chronic otitis media (HP:0000389)3.12736348
29Gastrointestinal infarctions (HP:0005244)3.10623411
30Abnormality of macrophages (HP:0004311)3.10183627
31Recurrent pneumonia (HP:0006532)3.03893607
32Recurrent gram-negative bacterial infections (HP:0005420)3.03786599
33Recurrent bronchitis (HP:0002837)3.01740118
34IgG deficiency (HP:0004315)2.98283235
35Autoimmune hemolytic anemia (HP:0001890)2.96733798
36Petechiae (HP:0000967)2.91353711
37Cellulitis (HP:0100658)2.89147527
38Abnormality of the prostate (HP:0008775)2.88054495
39Reduced antithrombin III activity (HP:0001976)2.85448065
40Abnormality of B cell number (HP:0010975)2.83768511
41B lymphocytopenia (HP:0010976)2.83768511
42Recurrent lower respiratory tract infections (HP:0002783)2.75240121
43Thyroiditis (HP:0100646)2.74797015
44Prolonged bleeding time (HP:0003010)2.74699845
45Osteomyelitis (HP:0002754)2.72004753
46Vacuolated lymphocytes (HP:0001922)2.70704927
47Gastrointestinal stroma tumor (HP:0100723)2.70406064
48Hypothermia (HP:0002045)2.68617149
49Chronic sinusitis (HP:0011109)2.67676922
50Abnormality of T cell physiology (HP:0011840)2.66016705
51Inflammation of the large intestine (HP:0002037)2.65107251
52Pustule (HP:0200039)2.65051602
53Chronic diarrhea (HP:0002028)2.64367940
54Anhidrosis (HP:0000970)2.62263802
55Lymphopenia (HP:0001888)2.61447104
56Abnormality of the pleura (HP:0002103)2.61243440
57Abnormality of T cells (HP:0002843)2.59323723
58Pulmonary infiltrates (HP:0002113)2.54720878
59Bronchitis (HP:0012387)2.52800275
60Abnormal number of erythroid precursors (HP:0012131)2.51601782
61Hypokalemic alkalosis (HP:0001949)2.51566698
62Recurrent sinusitis (HP:0011108)2.49477394
63Encephalitis (HP:0002383)2.49404724
64Abnormality of cells of the lymphoid lineage (HP:0012140)2.48956091
65Leukocytosis (HP:0001974)2.48745745
66Restrictive lung disease (HP:0002091)2.48652021
67Skin rash (HP:0000988)2.48248985
68Eosinophilia (HP:0001880)2.47914334
69Gastrointestinal inflammation (HP:0004386)2.44833862
70Chest pain (HP:0100749)2.44773861
71Type I transferrin isoform profile (HP:0003642)2.43806585
72Prostate neoplasm (HP:0100787)2.43499374
73Combined immunodeficiency (HP:0005387)2.41649863
74Reticulocytopenia (HP:0001896)2.41223621
75Granulocytopenia (HP:0001913)2.39773396
76Gingivitis (HP:0000230)2.38156931
77Decreased circulating renin level (HP:0003351)2.37650179
78Abnormality of cells of the erythroid lineage (HP:0012130)2.36854181
79Epistaxis (HP:0000421)2.36492992
80Hyperactive renin-angiotensin system (HP:0000841)2.35932598
81Colitis (HP:0002583)2.35519421
82Neutropenia (HP:0001875)2.33705528
83Aplastic anemia (HP:0001915)2.31047618
84Pulmonary embolism (HP:0002204)2.30969431
85Urticaria (HP:0001025)2.29879624
86Joint swelling (HP:0001386)2.29419955
87Stomach cancer (HP:0012126)2.29138611
88IgA deficiency (HP:0002720)2.28041801
89Abnormality of eosinophils (HP:0001879)2.27153741
90Arterial thrombosis (HP:0004420)2.27039245
91Periodontitis (HP:0000704)2.26780847
92Lymphoma (HP:0002665)2.26488498
93T lymphocytopenia (HP:0005403)2.26483891
94Gingival bleeding (HP:0000225)2.25493212
95Abnormality of T cell number (HP:0011839)2.24830976
96Keratoconjunctivitis (HP:0001096)2.23081758
97Emphysema (HP:0002097)2.22706865
98Viral hepatitis (HP:0006562)2.21482936
99Chromsome breakage (HP:0040012)2.18630948
100Basal ganglia calcification (HP:0002135)2.18224945
101Abnormality of male internal genitalia (HP:0000022)2.17732919
102Hyperaldosteronism (HP:0000859)2.16982754
103Alveolar cell carcinoma (HP:0006519)2.15762273
104Hemoptysis (HP:0002105)2.15495572
105Severe combined immunodeficiency (HP:0004430)2.14956081
106Microcytic anemia (HP:0001935)2.14336571
107Chromosomal breakage induced by crosslinking agents (HP:0003221)2.12880537
108Autoimmune thrombocytopenia (HP:0001973)2.12357370
109Gangrene (HP:0100758)2.11906534
110Abnormality of chloride homeostasis (HP:0011422)2.10321398
111Neoplasm of the tracheobronchial system (HP:0100552)2.08256448
112Keratoconjunctivitis sicca (HP:0001097)2.07756114
113Leukopenia (HP:0001882)2.07567049
114Pulmonary fibrosis (HP:0002206)2.06862417
115Skin ulcer (HP:0200042)2.06017711
116Abnormality of the right ventricle (HP:0001707)2.04748124
117Hyponatremia (HP:0002902)2.02701381
118Sepsis (HP:0100806)2.00426971
119Clubbing of toes (HP:0100760)1.96653994
120Hypoplasia of the thymus (HP:0000778)1.94976587
121Abnormal platelet function (HP:0011869)1.94140413
122Impaired platelet aggregation (HP:0003540)1.94140413
123Increased IgE level (HP:0003212)1.94117322
124Exertional dyspnea (HP:0002875)1.93879096
125Increased IgM level (HP:0003496)1.93758016
126Albinism (HP:0001022)1.92295608
127Acute hepatic failure (HP:0006554)1.91483689
128Amaurosis fugax (HP:0100576)1.90694323
129Arthralgia (HP:0002829)1.90391793
130Hypergammaglobulinemia (HP:0010702)1.89568483

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.68063440
2IRAK43.26027688
3TXK3.07837803
4KIT2.89744642
5TEC2.64768859
6IRAK32.59692272
7MAP3K142.48518140
8LMTK22.39751676
9BLK2.34384514
10BTK2.30424988
11IKBKE2.09837601
12NME21.95333759
13TBK11.94158009
14TYK21.89444643
15RIPK41.89028080
16SYK1.88489596
17CSF1R1.86867216
18TNIK1.81814050
19IKBKB1.78794842
20ZAP701.74673452
21TAOK11.74354540
22JAK31.72214420
23EIF2AK31.57078459
24TESK21.54833483
25MAPKAPK31.53450485
26MAP3K101.52924636
27STK161.50842268
28FES1.48246455
29TGFBR21.44672824
30ACVR1B1.41016571
31NLK1.40727836
32LYN1.40015006
33TAOK31.34066240
34TLK11.33900867
35EIF2AK21.30116932
36LCK1.27426420
37PRKG21.27338519
38CLK11.25404685
39HCK1.24925661
40PIM21.23499993
41SIK31.23124220
42MKNK21.22654636
43FLT31.17472413
44SRPK11.11802746
45ITK1.10556646
46PIM11.10392181
47JAK11.09550907
48STK101.08821247
49MKNK11.04596983
50MAP2K31.03852351
51CSK1.00570882
52MATK0.98375987
53MAPK110.95915257
54TGFBR10.93969978
55PRPF4B0.93063201
56CHUK0.92221909
57MAP2K20.92127782
58SIK20.91410264
59GRK60.89836022
60IRAK10.89035381
61ADRBK20.88604352
62YES10.86757343
63MST40.80469715
64FRK0.80216448
65MUSK0.79193083
66CCNB10.78992373
67MAP3K120.78941244
68ZAK0.78079767
69TAOK20.75212753
70RPS6KA40.74124192
71PASK0.73980954
72TNK20.72176347
73VRK10.72146199
74STK40.72030277
75TRPM70.71560656
76BMPR1B0.70662079
77HIPK20.68936822
78BMPR20.66636292
79VRK20.65492437
80MARK30.64043095
81BRD40.63565117
82GRK70.63257233
83KDR0.61671223
84NEK90.59549355
85MAP3K130.58781473
86EIF2AK10.58354645
87IRAK20.57477511
88PDK10.55899585
89ATR0.55354276
90FGFR30.54525343
91MAP3K110.50333882
92MAP3K10.49491606
93ERN10.49466402
94WEE10.48439839
95NUAK10.48193987
96DYRK30.48166025
97GRK10.47342589
98MAP3K30.46953305
99PRKCD0.46757044
100MAP2K60.46560379
101FYN0.44566562
102PRKCQ0.44485162
103MAPKAPK20.43996225
104MAP3K50.43341045
105LRRK20.42407291
106DAPK10.42098282
107CDK190.42057815
108MAPK40.41968370
109ABL10.40060517
110CDK40.37548336
111IGF1R0.36740180
112MAPK120.35907643
113RPS6KA50.34952214
114NEK20.34413270
115SCYL20.34122985
116MAPK30.32372461
117CAMKK20.32282528
118INSR0.32265506
119JAK20.32147686
120PIK3CG0.30646181
121TIE10.30277926
122FGR0.30058845
123MAP4K20.29090831
124SMG10.28674104
125PRKD20.27186339
126MAPK70.24403056
127CAMKK10.24069461
128ALK0.23702653
129MAP3K80.21986328
130CDK60.18019743

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.41527458
2Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.74746129
3DNA replication_Homo sapiens_hsa030302.69312188
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.67604803
5Leishmaniasis_Homo sapiens_hsa051402.54186561
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.44367501
7Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.27762853
8Measles_Homo sapiens_hsa051622.23050378
9B cell receptor signaling pathway_Homo sapiens_hsa046622.21227731
10Ribosome_Homo sapiens_hsa030102.20014552
11Allograft rejection_Homo sapiens_hsa053302.13609214
12Hematopoietic cell lineage_Homo sapiens_hsa046402.13230030
13RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.06145822
14Toll-like receptor signaling pathway_Homo sapiens_hsa046202.02047610
15Mismatch repair_Homo sapiens_hsa034301.88183285
16Graft-versus-host disease_Homo sapiens_hsa053321.86380171
17Base excision repair_Homo sapiens_hsa034101.86237723
18Herpes simplex infection_Homo sapiens_hsa051681.85371817
19Osteoclast differentiation_Homo sapiens_hsa043801.81408068
20Antigen processing and presentation_Homo sapiens_hsa046121.74158847
21Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.72049708
22Homologous recombination_Homo sapiens_hsa034401.70065986
23NOD-like receptor signaling pathway_Homo sapiens_hsa046211.65496009
24Other glycan degradation_Homo sapiens_hsa005111.60287334
25Asthma_Homo sapiens_hsa053101.56725230
26Legionellosis_Homo sapiens_hsa051341.52670990
27Influenza A_Homo sapiens_hsa051641.46429352
28Pertussis_Homo sapiens_hsa051331.45320875
29Malaria_Homo sapiens_hsa051441.43647108
30Tuberculosis_Homo sapiens_hsa051521.43071816
31Jak-STAT signaling pathway_Homo sapiens_hsa046301.39846278
32Staphylococcus aureus infection_Homo sapiens_hsa051501.38083459
33Non-homologous end-joining_Homo sapiens_hsa034501.33742106
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.27337884
35Pyrimidine metabolism_Homo sapiens_hsa002401.27214462
36Fanconi anemia pathway_Homo sapiens_hsa034601.25136615
37T cell receptor signaling pathway_Homo sapiens_hsa046601.22085742
38Nucleotide excision repair_Homo sapiens_hsa034201.21904842
39Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.20360371
40Autoimmune thyroid disease_Homo sapiens_hsa053201.19678180
41Transcriptional misregulation in cancer_Homo sapiens_hsa052021.17107014
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.14359296
43RNA polymerase_Homo sapiens_hsa030201.07281483
44Rheumatoid arthritis_Homo sapiens_hsa053231.05751541
45Toxoplasmosis_Homo sapiens_hsa051451.05087245
46Spliceosome_Homo sapiens_hsa030401.04601553
47Apoptosis_Homo sapiens_hsa042101.04520866
48Hepatitis B_Homo sapiens_hsa051611.03545020
49Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.03376429
50Shigellosis_Homo sapiens_hsa051311.02747525
51TNF signaling pathway_Homo sapiens_hsa046681.01048187
52Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.96680293
53Chemokine signaling pathway_Homo sapiens_hsa040620.95408870
54Salmonella infection_Homo sapiens_hsa051320.95309821
55Epstein-Barr virus infection_Homo sapiens_hsa051690.95027005
56Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.92797637
57African trypanosomiasis_Homo sapiens_hsa051430.89239838
58Type I diabetes mellitus_Homo sapiens_hsa049400.88991466
59Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85888737
60SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84669284
61Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.84273578
62Acute myeloid leukemia_Homo sapiens_hsa052210.82793575
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81591239
64Glycosaminoglycan degradation_Homo sapiens_hsa005310.78458853
65Leukocyte transendothelial migration_Homo sapiens_hsa046700.76197998
66Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.74196158
67alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.73640569
68Hepatitis C_Homo sapiens_hsa051600.73601163
69Phagosome_Homo sapiens_hsa041450.73266011
70p53 signaling pathway_Homo sapiens_hsa041150.72970382
71Systemic lupus erythematosus_Homo sapiens_hsa053220.71699833
72RNA degradation_Homo sapiens_hsa030180.71554392
73Lysosome_Homo sapiens_hsa041420.65126077
74Platelet activation_Homo sapiens_hsa046110.64096527
75Protein export_Homo sapiens_hsa030600.63712687
76Proteasome_Homo sapiens_hsa030500.62850271
77Viral myocarditis_Homo sapiens_hsa054160.62331608
78Viral carcinogenesis_Homo sapiens_hsa052030.60610056
79Basal transcription factors_Homo sapiens_hsa030220.59079827
80Caffeine metabolism_Homo sapiens_hsa002320.56995315
81Purine metabolism_Homo sapiens_hsa002300.56888315
82Cell cycle_Homo sapiens_hsa041100.56468716
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.54160581
84HTLV-I infection_Homo sapiens_hsa051660.53552939
85Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.53351302
86Non-small cell lung cancer_Homo sapiens_hsa052230.46408055
87Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.44342420
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41208104
89One carbon pool by folate_Homo sapiens_hsa006700.38987859
90Arachidonic acid metabolism_Homo sapiens_hsa005900.38382962
91Regulation of autophagy_Homo sapiens_hsa041400.38053766
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37169789
93AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.36778319
94Chronic myeloid leukemia_Homo sapiens_hsa052200.36463155
95Sphingolipid metabolism_Homo sapiens_hsa006000.33790840
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.32576059
97Folate biosynthesis_Homo sapiens_hsa007900.32554174
98ABC transporters_Homo sapiens_hsa020100.30705833
99Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.30392517
100N-Glycan biosynthesis_Homo sapiens_hsa005100.30376871
101Pancreatic cancer_Homo sapiens_hsa052120.30079813
102Notch signaling pathway_Homo sapiens_hsa043300.29366713
103Linoleic acid metabolism_Homo sapiens_hsa005910.29081624
104Dorso-ventral axis formation_Homo sapiens_hsa043200.28588376
105Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27130479
106Prolactin signaling pathway_Homo sapiens_hsa049170.26408686
107Sulfur relay system_Homo sapiens_hsa041220.24756546
108Nitrogen metabolism_Homo sapiens_hsa009100.22527633
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.20462503
110Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.20133771
111MAPK signaling pathway_Homo sapiens_hsa040100.20118365
112Glycerophospholipid metabolism_Homo sapiens_hsa005640.18893603
113Renal cell carcinoma_Homo sapiens_hsa052110.16924326
114Sphingolipid signaling pathway_Homo sapiens_hsa040710.14702592
115Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.12109236
116Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.11512124
117Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.10814434
118Peroxisome_Homo sapiens_hsa041460.09967410
119Alcoholism_Homo sapiens_hsa050340.09763456
120Adipocytokine signaling pathway_Homo sapiens_hsa049200.08905456
121mTOR signaling pathway_Homo sapiens_hsa041500.07034078
122Phosphatidylinositol signaling system_Homo sapiens_hsa040700.06588224
123HIF-1 signaling pathway_Homo sapiens_hsa040660.06004096

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