STARD10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.46800068
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.46800068
3L-phenylalanine metabolic process (GO:0006558)7.24503348
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.24503348
5aromatic amino acid family catabolic process (GO:0009074)6.66624164
6tryptophan catabolic process (GO:0006569)5.97770827
7indole-containing compound catabolic process (GO:0042436)5.97770827
8indolalkylamine catabolic process (GO:0046218)5.97770827
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.95725522
10glyoxylate metabolic process (GO:0046487)5.82632051
11kynurenine metabolic process (GO:0070189)5.82380103
12cysteine metabolic process (GO:0006534)5.72386345
13tryptophan metabolic process (GO:0006568)5.63077678
14bile acid biosynthetic process (GO:0006699)5.62848555
15sulfur amino acid catabolic process (GO:0000098)5.59929914
16epoxygenase P450 pathway (GO:0019373)5.55148830
17urea metabolic process (GO:0019627)5.48177918
18urea cycle (GO:0000050)5.48177918
19alpha-linolenic acid metabolic process (GO:0036109)5.34747985
20high-density lipoprotein particle remodeling (GO:0034375)5.26598969
21negative regulation of fibrinolysis (GO:0051918)5.20811234
22serine family amino acid catabolic process (GO:0009071)5.17995004
23nitrogen cycle metabolic process (GO:0071941)5.06901506
24peptidyl-glutamic acid carboxylation (GO:0017187)4.99337396
25protein carboxylation (GO:0018214)4.99337396
26fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.97697479
27regulation of fibrinolysis (GO:0051917)4.97023481
28lysine catabolic process (GO:0006554)4.95427663
29lysine metabolic process (GO:0006553)4.95427663
30homocysteine metabolic process (GO:0050667)4.92195530
31aromatic amino acid family metabolic process (GO:0009072)4.89395268
32complement activation, alternative pathway (GO:0006957)4.88625723
33bile acid metabolic process (GO:0008206)4.86760461
34regulation of protein activation cascade (GO:2000257)4.86690596
35amino-acid betaine metabolic process (GO:0006577)4.72004942
36regulation of triglyceride catabolic process (GO:0010896)4.66182360
37reverse cholesterol transport (GO:0043691)4.62988811
38regulation of cholesterol esterification (GO:0010872)4.60984273
39alpha-amino acid catabolic process (GO:1901606)4.60546668
40tyrosine metabolic process (GO:0006570)4.57908138
41cellular ketone body metabolic process (GO:0046950)4.54488915
42regulation of complement activation (GO:0030449)4.54263154
43plasma lipoprotein particle remodeling (GO:0034369)4.49198968
44protein-lipid complex remodeling (GO:0034368)4.49198968
45macromolecular complex remodeling (GO:0034367)4.49198968
46negative regulation of cholesterol transport (GO:0032375)4.48840469
47negative regulation of sterol transport (GO:0032372)4.48840469
48triglyceride homeostasis (GO:0070328)4.42887301
49acylglycerol homeostasis (GO:0055090)4.42887301
50desmosome organization (GO:0002934)4.41094059
51omega-hydroxylase P450 pathway (GO:0097267)4.39730053
52phospholipid efflux (GO:0033700)4.35337614
53ethanol metabolic process (GO:0006067)4.33055562
54cellular amino acid catabolic process (GO:0009063)4.30932938
55glycine metabolic process (GO:0006544)4.28675088
56serine family amino acid metabolic process (GO:0009069)4.28501068
57glutamate metabolic process (GO:0006536)4.26102735
58bile acid and bile salt transport (GO:0015721)4.25571788
59cellular modified amino acid catabolic process (GO:0042219)4.22805547
60indolalkylamine metabolic process (GO:0006586)4.22514904
61coenzyme catabolic process (GO:0009109)4.21876092
62drug catabolic process (GO:0042737)4.19152010
63cellular glucuronidation (GO:0052695)4.15373232
64plasma lipoprotein particle clearance (GO:0034381)4.12589831
65cellular biogenic amine catabolic process (GO:0042402)4.08943529
66amine catabolic process (GO:0009310)4.08943529
67benzene-containing compound metabolic process (GO:0042537)4.05666905
68regulation of branching involved in prostate gland morphogenesis (GO:0060687)4.04248045
69ethanol oxidation (GO:0006069)4.04245261
70serine family amino acid biosynthetic process (GO:0009070)4.03430262
71imidazole-containing compound metabolic process (GO:0052803)4.02081757
72drug transmembrane transport (GO:0006855)3.97809694
73proline metabolic process (GO:0006560)3.94460935
74ketone body metabolic process (GO:1902224)3.92226193
75cholesterol efflux (GO:0033344)3.91522898
76arginine metabolic process (GO:0006525)3.90159853
77short-chain fatty acid metabolic process (GO:0046459)3.87515688
78phenylpropanoid metabolic process (GO:0009698)3.84089550
79primary alcohol catabolic process (GO:0034310)3.84058158
80dicarboxylic acid biosynthetic process (GO:0043650)3.83370626
81regulation of cholesterol biosynthetic process (GO:0045540)3.82788461
82aldehyde catabolic process (GO:0046185)3.81857176
83regulation of cholesterol homeostasis (GO:2000188)3.81206029
84organic acid catabolic process (GO:0016054)3.80130083
85carboxylic acid catabolic process (GO:0046395)3.80130083
86urate metabolic process (GO:0046415)3.78828241
87proline biosynthetic process (GO:0006561)3.78081561
88plasma lipoprotein particle assembly (GO:0034377)3.77972251
89ear development (GO:0043583)3.76093962
90positive regulation of lipoprotein lipase activity (GO:0051006)3.75849635
91positive regulation of triglyceride lipase activity (GO:0061365)3.75849635
92positive regulation of Cdc42 GTPase activity (GO:0043089)3.73502383
93intestinal epithelial cell development (GO:0060576)3.72681031
94aspartate family amino acid catabolic process (GO:0009068)3.72648663
95uronic acid metabolic process (GO:0006063)3.72382992
96glucuronate metabolic process (GO:0019585)3.72382992
97exogenous drug catabolic process (GO:0042738)3.71898309
98fibrinolysis (GO:0042730)3.71032313
99acetyl-CoA metabolic process (GO:0006084)3.66280365
100positive regulation of cellular amine metabolic process (GO:0033240)3.65939382
101regulation of bile acid biosynthetic process (GO:0070857)3.65825804
102cholesterol homeostasis (GO:0042632)3.64645194
103phospholipid homeostasis (GO:0055091)3.62640543
104low-density lipoprotein particle remodeling (GO:0034374)3.62049917
105cofactor catabolic process (GO:0051187)3.61565601
106regulation of fatty acid beta-oxidation (GO:0031998)3.61274828
107flavonoid metabolic process (GO:0009812)3.61127417
108sterol homeostasis (GO:0055092)3.60071621
109drug metabolic process (GO:0017144)3.57473029
110response to food (GO:0032094)3.57229371
111negative regulation of lipase activity (GO:0060192)3.55675527
112positive regulation of lipid catabolic process (GO:0050996)3.53744630
113blood coagulation, intrinsic pathway (GO:0007597)3.53498697
1142-oxoglutarate metabolic process (GO:0006103)3.52923437
115monocarboxylic acid catabolic process (GO:0072329)3.52584349
116fatty acid oxidation (GO:0019395)3.52254875
117fatty acid beta-oxidation (GO:0006635)3.52017841
118positive regulation of fatty acid beta-oxidation (GO:0032000)3.48122728
119calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.47209433
120regulation of cholesterol metabolic process (GO:0090181)3.45289268
121amyloid precursor protein catabolic process (GO:0042987)3.43449483
122COPI coating of Golgi vesicle (GO:0048205)3.43290499
123Golgi transport vesicle coating (GO:0048200)3.43290499
124vagina development (GO:0060068)3.41252490
125glucose 6-phosphate metabolic process (GO:0051156)3.29511942
126regulation of water loss via skin (GO:0033561)3.26444926
127glutamine family amino acid biosynthetic process (GO:0009084)3.22885536
128multicellular organismal water homeostasis (GO:0050891)3.19568832
129negative regulation of cell size (GO:0045792)3.18297208
130positive regulation of keratinocyte differentiation (GO:0045618)3.10469037
131uterus development (GO:0060065)3.07866065
132regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.06099386
133branching involved in mammary gland duct morphogenesis (GO:0060444)2.99137928
134biotin metabolic process (GO:0006768)2.98966362
135negative regulation of fatty acid transport (GO:2000192)2.96900302
136maintenance of gastrointestinal epithelium (GO:0030277)2.95737759
137GDP-mannose metabolic process (GO:0019673)2.94121965
138norepinephrine metabolic process (GO:0042415)2.93682362
139NADH metabolic process (GO:0006734)2.90660553
140very-low-density lipoprotein particle assembly (GO:0034379)2.89409314
141intestinal cholesterol absorption (GO:0030299)2.86066828
142fructose metabolic process (GO:0006000)2.85442134
143positive regulation of hormone metabolic process (GO:0032352)2.84489779
144maternal placenta development (GO:0001893)2.83948603
145nitric oxide biosynthetic process (GO:0006809)2.82149368
146negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.81998661
147regulation of plasminogen activation (GO:0010755)2.78668819
148striated muscle atrophy (GO:0014891)2.76503218
149negative regulation of fatty acid metabolic process (GO:0045922)2.75949646
150acute-phase response (GO:0006953)2.73276652
151regulation of cell proliferation involved in kidney development (GO:1901722)2.71404928
152retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.70971037
153phosphate ion homeostasis (GO:0055062)2.69910256
154trivalent inorganic anion homeostasis (GO:0072506)2.69910256
155amyloid precursor protein metabolic process (GO:0042982)2.69301683

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.12690474
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.06982598
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.41515037
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.27034835
5* FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.00165187
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.91895811
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.81448372
8ESR1_20079471_ChIP-ChIP_T-47D_Human4.10869581
9* NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.74919907
10CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.72069835
11TP63_17297297_ChIP-ChIP_HaCaT_Human3.63402507
12TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.55288328
13* TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.79792306
14* RUNX1_27514584_Chip-Seq_MCF-7_Human2.46881366
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.17487365
16TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.11450970
17HIF1A_21447827_ChIP-Seq_MCF-7_Human2.05910007
18* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.02072971
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.5051185
20P68_20966046_ChIP-Seq_HELA_Human1.65708253
21SMC4_20622854_ChIP-Seq_HELA_Human1.65156588
22* FOXA2_19822575_ChIP-Seq_HepG2_Human1.59024001
23ELK3_25401928_ChIP-Seq_HUVEC_Human1.52596422
24CLOCK_20551151_ChIP-Seq_293T_Human1.49638666
25CREB1_26743006_Chip-Seq_LNCaP_Human1.48991223
26CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.48704418
27* HNF4A_19822575_ChIP-Seq_HepG2_Human1.44571990
28KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.43427243
29AHR_22903824_ChIP-Seq_MCF-7_Human1.43081886
30ZNF217_24962896_ChIP-Seq_MCF-7_Human1.41577672
31VDR_21846776_ChIP-Seq_THP-1_Human1.38660146
32CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.38582390
33KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.36970189
34SOX2_27498859_Chip-Seq_STOMACH_Mouse1.36937279
35TCF7_22412390_ChIP-Seq_EML_Mouse1.34793048
36GATA1_22025678_ChIP-Seq_K562_Human1.31566647
37STAT6_21828071_ChIP-Seq_BEAS2B_Human1.29971521
38STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.28764572
39HTT_18923047_ChIP-ChIP_STHdh_Human1.27816185
40KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.27655009
41* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.27350432
42KDM2B_26808549_Chip-Seq_SUP-B15_Human1.26547417
43EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25339159
44RXRA_24833708_ChIP-Seq_LIVER_Mouse1.25122998
45ATF3_27146783_Chip-Seq_COLON_Human1.23738912
46P63_26484246_Chip-Seq_KERATINOCYTES_Human1.23027096
47DNAJC2_21179169_ChIP-ChIP_NT2_Human1.22563996
48EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.22168336
49THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.20534225
50SA1_27219007_Chip-Seq_ERYTHROID_Human1.20437540
51ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.19447742
52KDM2B_26808549_Chip-Seq_K562_Human1.16772015
53ZNF263_19887448_ChIP-Seq_K562_Human1.14193835
54* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13119990
55* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.13060621
56RARG_19884340_ChIP-ChIP_MEFs_Mouse1.11615185
57KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.10565536
58* GATA4_25053715_ChIP-Seq_YYC3_Human1.09492114
59KLF5_25053715_ChIP-Seq_YYC3_Human1.09399590
60TP63_22573176_ChIP-Seq_HFKS_Human1.07835508
61TDRD3_21172665_ChIP-Seq_MCF-7_Human1.07405279
62E2F1_20622854_ChIP-Seq_HELA_Human1.05589255
63CTCF_27219007_Chip-Seq_ERYTHROID_Human1.05064984
64PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.04317228
65TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.03775813
66ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.03673826
67ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.02822605
68* KDM2B_26808549_Chip-Seq_DND41_Human1.01639160
69STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.00047893
70UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.99325303
71PKCTHETA_26484144_Chip-Seq_BREAST_Human0.98666722
72ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.98647589
73* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.98205284
74CTCF_26484167_Chip-Seq_Bcells_Mouse0.96361673
75ESR2_21235772_ChIP-Seq_MCF-7_Human0.95978474
76PHF8_20622854_ChIP-Seq_HELA_Human0.94938093
77JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.93567833
78SA1_27219007_Chip-Seq_Bcells_Human0.92789699
79STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.92643382
80ELF1_20517297_ChIP-Seq_JURKAT_Human0.90526142
81ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.90340664
82RARA_24833708_ChIP-Seq_LIVER_Mouse0.88267617
83MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.87559684
84SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.86373103
85SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.85924670
86LXR_22292898_ChIP-Seq_THP-1_Human0.85615335
87NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.82557372
88ESR1_15608294_ChIP-ChIP_MCF-7_Human0.81875975
89IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.79104672
90BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.78597522
91RAD21_21589869_ChIP-Seq_MESCs_Mouse0.77072500
92* KAP1_22055183_ChIP-Seq_ESCs_Mouse0.76675573
93CDX2_20551321_ChIP-Seq_CACO-2_Human0.76319477
94ESR1_21235772_ChIP-Seq_MCF-7_Human0.75555970
95AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.74925188
96AUTS2_25519132_ChIP-Seq_293T-REX_Human0.74399250
97RARB_24833708_ChIP-Seq_LIVER_Mouse0.73557678
98STAT3_1855785_ChIP-Seq_MESCs_Mouse0.72844796
99GATA6_25053715_ChIP-Seq_YYC3_Human0.72002642
100* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.67061041
101PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.66662569
102SALL4_18804426_ChIP-ChIP_XEN_Mouse0.65151886
103IRF8_22096565_ChIP-ChIP_GC-B_Human0.64663692
104FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.64614482
105PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.64513561
106BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.64383233
107CEBPB_22108803_ChIP-Seq_LS180_Human0.64374161
108PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.62687548
109P53_21459846_ChIP-Seq_SAOS-2_Human0.62064769
110RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.61509272
111SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.60135492
112TET1_21451524_ChIP-Seq_MESCs_Mouse0.58583701
113RACK7_27058665_Chip-Seq_MCF-7_Human0.57395175
114* MYC_19915707_ChIP-ChIP_AK7_Human0.57207308
115EGR1_19032775_ChIP-ChIP_M12_Human0.57198526
116BCOR_27268052_Chip-Seq_Bcells_Human0.55968189
117* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.55674893
118SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.55506051
119Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.55114975
120* AR_20517297_ChIP-Seq_VCAP_Human0.55096698
121* FOXA1_25552417_ChIP-Seq_VCAP_Human0.54491711
122PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.54286907
123TAF2_19829295_ChIP-Seq_ESCs_Human0.53988463
124STAT1_17558387_ChIP-Seq_HELA_Human0.53142908
125GATA1_19941826_ChIP-Seq_K562_Human0.53028355
126* ESET_19884257_ChIP-Seq_ESCs_Mouse0.52849982
127SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.52395234
128CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.50731020
129FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.50277862
130PPAR_26484153_Chip-Seq_NCI-H1993_Human0.50103261
131GATA1_19941827_ChIP-Seq_MEL_Mouse0.49425421
132ERG_20517297_ChIP-Seq_VCAP_Human0.49251570
133* FOXO3_23340844_ChIP-Seq_DLD1_Human0.49106115
134GATA2_19941826_ChIP-Seq_K562_Human0.47931945
135SRY_22984422_ChIP-ChIP_TESTIS_Rat0.47698576
136* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.45728684
137ERG_21242973_ChIP-ChIP_JURKAT_Human0.45715473
138* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.45285788
139GATA3_24758297_ChIP-Seq_MCF-7_Human0.45141844
140* GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.44759150
141* EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.44541108
142TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.44350946
143CTCF_27219007_Chip-Seq_Bcells_Human0.44219660
144* MYC_27129775_Chip-Seq_CORNEA_Mouse0.44210526
145RAC3_21632823_ChIP-Seq_H3396_Human0.43981117
146CSB_26484114_Chip-Seq_FIBROBLAST_Human0.43807577
147* SOX2_20726797_ChIP-Seq_SW620_Human0.43698810
148BCL6_27268052_Chip-Seq_Bcells_Human0.43260536
149* CBP_21632823_ChIP-Seq_H3396_Human0.43220213
150SOX2_22085726_ChIP-Seq_NPCs_Mouse0.43198323

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.14128358
2MP0005360_urolithiasis7.43929029
3MP0005085_abnormal_gallbladder_physiolo6.21440074
4MP0005365_abnormal_bile_salt6.00429670
5MP0008875_abnormal_xenobiotic_pharmacok4.99303245
6MP0003806_abnormal_nucleotide_metabolis4.07700651
7MP0003252_abnormal_bile_duct3.80091304
8MP0010329_abnormal_lipoprotein_level3.42502893
9MP0009840_abnormal_foam_cell3.31330064
10MP0005083_abnormal_biliary_tract3.07478182
11MP0003195_calcinosis2.98683350
12MP0005332_abnormal_amino_acid2.98015359
13MP0001666_abnormal_nutrient_absorption2.86548142
14MP0009780_abnormal_chondrocyte_physiolo2.77544848
15MP0004019_abnormal_vitamin_homeostasis2.44594936
16MP0002098_abnormal_vibrissa_morphology2.41706316
17MP0003191_abnormal_cellular_cholesterol2.37436238
18MP0002138_abnormal_hepatobiliary_system2.16095139
19MP0000566_synostosis2.13231473
20MP0000609_abnormal_liver_physiology2.08430088
21MP0002118_abnormal_lipid_homeostasis2.07563901
22MP0003123_paternal_imprinting1.98581222
23MP0003868_abnormal_feces_composition1.96260016
24MP0005319_abnormal_enzyme/_coenzyme1.84154373
25MP0001873_stomach_inflammation1.83664793
26MP0005501_abnormal_skin_physiology1.75463702
27MP0010678_abnormal_skin_adnexa1.69267799
28MP0001764_abnormal_homeostasis1.69211360
29MP0005076_abnormal_cell_differentiation1.66945819
30MP0000462_abnormal_digestive_system1.65573740
31MP0002249_abnormal_larynx_morphology1.64104566
32MP0000383_abnormal_hair_follicle1.62667932
33MP0009643_abnormal_urine_homeostasis1.59773901
34MP0005584_abnormal_enzyme/coenzyme_acti1.57622527
35MP0004381_abnormal_hair_follicle1.55715848
36MP0001664_abnormal_digestion1.52543376
37MP0005451_abnormal_body_composition1.48675531
38MP0005377_hearing/vestibular/ear_phenot1.47639403
39MP0003878_abnormal_ear_physiology1.47639403
40MP0002909_abnormal_adrenal_gland1.44652819
41MP0000678_abnormal_parathyroid_gland1.43715797
42MP0005409_darkened_coat_color1.39981912
43MP0003186_abnormal_redox_activity1.34398759
44MP0000467_abnormal_esophagus_morphology1.34306507
45MP0002089_abnormal_postnatal_growth/wei1.32437342
46MP0003879_abnormal_hair_cell1.30354254
47MP0003011_delayed_dark_adaptation1.27523874
48MP0005636_abnormal_mineral_homeostasis1.27048916
49MP0003453_abnormal_keratinocyte_physiol1.26553623
50MP0003183_abnormal_peptide_metabolism1.25400143
51MP0003656_abnormal_erythrocyte_physiolo1.22230553
52MP0000377_abnormal_hair_follicle1.20317192
53MP0000470_abnormal_stomach_morphology1.19174339
54MP0003705_abnormal_hypodermis_morpholog1.18978349
55MP0000427_abnormal_hair_cycle1.17132043
56MP0009697_abnormal_copulation1.15661035
57MP0000598_abnormal_liver_morphology1.14809505
58MP0004185_abnormal_adipocyte_glucose1.09273305
59MP0000627_abnormal_mammary_gland1.08556865
60MP0001727_abnormal_embryo_implantation1.03830444
61MP0005647_abnormal_sex_gland1.01886135
62MP0003866_abnormal_defecation0.99520733
63MP0000604_amyloidosis0.99210913
64MP0006036_abnormal_mitochondrial_physio0.97783870
65MP0009764_decreased_sensitivity_to0.95961006
66MP0001849_ear_inflammation0.95138943
67MP0001756_abnormal_urination0.93553173
68MP0001216_abnormal_epidermal_layer0.91572036
69MP0005084_abnormal_gallbladder_morpholo0.91304902
70MP0009642_abnormal_blood_homeostasis0.90384829
71MP0005220_abnormal_exocrine_pancreas0.89717225
72MP0005670_abnormal_white_adipose0.89588839
73MP0010155_abnormal_intestine_physiology0.88546961
74MP0009763_increased_sensitivity_to0.87777383
75MP0002254_reproductive_system_inflammat0.86610908
76MP0008469_abnormal_protein_level0.84738259
77MP0008260_abnormal_autophagy0.84535495
78MP0004043_abnormal_pH_regulation0.83556033
79MP0000477_abnormal_intestine_morphology0.83340746
80MP0002078_abnormal_glucose_homeostasis0.82833262
81MP0002876_abnormal_thyroid_physiology0.82333795
82MP0005646_abnormal_pituitary_gland0.82021491
83MP0005408_hypopigmentation0.80699953
84MP0003941_abnormal_skin_development0.80455165
85MP0000537_abnormal_urethra_morphology0.75584733
86MP0005376_homeostasis/metabolism_phenot0.75325929
87MP0010771_integument_phenotype0.75027015
88MP0009931_abnormal_skin_appearance0.74115888
89MP0010368_abnormal_lymphatic_system0.72930796
90MP0009765_abnormal_xenobiotic_induced0.72388252
91MP0002136_abnormal_kidney_physiology0.68830074
92MP0003329_amyloid_beta_deposits0.67845530
93MP0002132_abnormal_respiratory_system0.67794084
94MP0004858_abnormal_nervous_system0.67711814
95MP0005535_abnormal_body_temperature0.66792460
96MP0003936_abnormal_reproductive_system0.65439523
97MP0002971_abnormal_brown_adipose0.65310399
98MP0005381_digestive/alimentary_phenotyp0.64722928
99MP0001765_abnormal_ion_homeostasis0.64672156
100MP0005334_abnormal_fat_pad0.64015210
101MP0005375_adipose_tissue_phenotype0.63282386
102MP0004130_abnormal_muscle_cell0.63132099
103MP0000003_abnormal_adipose_tissue0.62401301
104MP0010234_abnormal_vibrissa_follicle0.62272436
105MP0004233_abnormal_muscle_weight0.62121557
106MP0004264_abnormal_extraembryonic_tissu0.60470949
107MP0001661_extended_life_span0.60339076
108MP0005266_abnormal_metabolism0.60221917
109MP0002822_catalepsy0.59694355
110MP0006035_abnormal_mitochondrial_morpho0.59214329
111MP0002796_impaired_skin_barrier0.56370128
112MP0009053_abnormal_anal_canal0.56238854
113MP0002928_abnormal_bile_duct0.52944691
114MP0005448_abnormal_energy_balance0.52565043
115MP0003638_abnormal_response/metabolism_0.52146633
116MP0000639_abnormal_adrenal_gland0.49716324
117MP0005666_abnormal_adipose_tissue0.49562579
118MP0005395_other_phenotype0.49384741
119MP0003953_abnormal_hormone_level0.48255119
120MP0005058_abnormal_lysosome_morphology0.47838957
121MP0004782_abnormal_surfactant_physiolog0.47815534
122MP0003690_abnormal_glial_cell0.46136424
123MP0002837_dystrophic_cardiac_calcinosis0.42424634
124MP0003718_maternal_effect0.41879519
125MP0005464_abnormal_platelet_physiology0.41284241
126MP0008873_increased_physiological_sensi0.41191933
127MP0005166_decreased_susceptibility_to0.41161555
128MP0003300_gastrointestinal_ulcer0.40428038
129MP0000230_abnormal_systemic_arterial0.40422794
130MP0008872_abnormal_physiological_respon0.39879191
131MP0003075_altered_response_to0.37581532
132MP0002168_other_aberrant_phenotype0.36632741
133MP0001944_abnormal_pancreas_morphology0.36424991
134MP0008874_decreased_physiological_sensi0.36368261
135MP0009672_abnormal_birth_weight0.35718020
136MP0005410_abnormal_fertilization0.33298400
137MP0000579_abnormal_nail_morphology0.33026947
138MP0002135_abnormal_kidney_morphology0.30716855
139MP0000538_abnormal_urinary_bladder0.30210532
140MP0009384_cardiac_valve_regurgitation0.29947366
141MP0005167_abnormal_blood-brain_barrier0.28920865
142MP0001845_abnormal_inflammatory_respons0.28002889
143MP0002970_abnormal_white_adipose0.27933097
144MP0009115_abnormal_fat_cell0.27153421
145MP0000249_abnormal_blood_vessel0.26579446
146MP0001881_abnormal_mammary_gland0.26550672
147MP0005248_abnormal_Harderian_gland0.26214512

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.27512308
2Intrahepatic cholestasis (HP:0001406)6.85942579
3Deep venous thrombosis (HP:0002625)6.73807434
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.45184350
5Xanthomatosis (HP:0000991)6.00845227
6Hypobetalipoproteinemia (HP:0003563)5.88702380
7Prolonged partial thromboplastin time (HP:0003645)5.84009003
8Hyperlipoproteinemia (HP:0010980)5.22256470
9J-shaped sella turcica (HP:0002680)4.84528288
10Complement deficiency (HP:0004431)4.75932834
11Hyperammonemia (HP:0001987)4.67751589
12Ketosis (HP:0001946)4.50135022
13Hypolipoproteinemia (HP:0010981)4.48085350
14Hyperglycinemia (HP:0002154)4.40091530
15Abnormality of glutamine family amino acid metabolism (HP:0010902)4.37857289
16Joint hemorrhage (HP:0005261)4.27584398
17Hyperglycinuria (HP:0003108)4.22375247
18Abnormality of sulfur amino acid metabolism (HP:0004339)4.22137911
19Asymmetry of the thorax (HP:0001555)4.12552385
20Abnormality of aspartate family amino acid metabolism (HP:0010899)4.12349224
21Abnormality of the common coagulation pathway (HP:0010990)4.07833860
22Hypoglycemic coma (HP:0001325)4.06314347
23Abnormality of serine family amino acid metabolism (HP:0010894)4.06161931
24Abnormality of glycine metabolism (HP:0010895)4.06161931
25Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.05496167
26Epidermoid cyst (HP:0200040)4.05203252
27Septate vagina (HP:0001153)4.01827359
28Hypoalphalipoproteinemia (HP:0003233)3.98351681
29Abnormality of methionine metabolism (HP:0010901)3.96891829
30Fat malabsorption (HP:0002630)3.96278047
31Flat acetabular roof (HP:0003180)3.68679205
32Abnormality of the intrinsic pathway (HP:0010989)3.60930191
33Abnormality of pyrimidine metabolism (HP:0004353)3.57631920
34Abnormality of fatty-acid metabolism (HP:0004359)3.54858453
35Conjugated hyperbilirubinemia (HP:0002908)3.49802317
36Abnormality of complement system (HP:0005339)3.44923194
37Ketoacidosis (HP:0001993)3.40909894
38Gout (HP:0001997)3.38306019
39Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.34313722
40Hypercholesterolemia (HP:0003124)3.33497134
41Abnormality of nucleobase metabolism (HP:0010932)3.28594180
42Distal lower limb muscle weakness (HP:0009053)3.27765410
43Hyperbilirubinemia (HP:0002904)3.26065618
44Abdominal distention (HP:0003270)3.15589115
45Abnormality of purine metabolism (HP:0004352)3.14075311
46Thin bony cortex (HP:0002753)3.12758175
47Delayed CNS myelination (HP:0002188)3.11565551
48Concave nail (HP:0001598)3.10997391
49Abnormality of serum amino acid levels (HP:0003112)3.01607924
50Amelogenesis imperfecta (HP:0000705)2.96283386
51Metabolic acidosis (HP:0001942)2.94258255
52Steatorrhea (HP:0002570)2.93922222
53Hepatocellular carcinoma (HP:0001402)2.87971047
54Dicarboxylic aciduria (HP:0003215)2.87112579
55Abnormality of dicarboxylic acid metabolism (HP:0010995)2.87112579
56Lethargy (HP:0001254)2.80728978
57Vascular calcification (HP:0004934)2.79047266
58Lymphangioma (HP:0100764)2.74708562
59Right ventricular cardiomyopathy (HP:0011663)2.74626174
60Spontaneous abortion (HP:0005268)2.72690466
61Malnutrition (HP:0004395)2.62241371
62Myocardial infarction (HP:0001658)2.60288689
63Hypoglycemic seizures (HP:0002173)2.55206626
64Generalized aminoaciduria (HP:0002909)2.51705985
65Skin nodule (HP:0200036)2.51344254
66Irritability (HP:0000737)2.46794785
67Abnormal tarsal ossification (HP:0008369)2.46138823
68Deformed sella turcica (HP:0002681)2.46001107
69Late onset (HP:0003584)2.45955381
70Cerebral edema (HP:0002181)2.45702524
71Cardiovascular calcification (HP:0011915)2.45008500
72Hypochromic microcytic anemia (HP:0004840)2.44992220
73Urinary glycosaminoglycan excretion (HP:0003541)2.42961022
74Mucopolysacchariduria (HP:0008155)2.42961022
75Increased neuronal autofluorescent lipopigment (HP:0002074)2.42760815
76Germ cell neoplasia (HP:0100728)2.42713499
77Testicular neoplasm (HP:0010788)2.40712797
78Systemic lupus erythematosus (HP:0002725)2.40573552
79Spastic diplegia (HP:0001264)2.40507110
80Acanthocytosis (HP:0001927)2.40209075
81Neonatal onset (HP:0003623)2.39819035
82Abnormal gallbladder physiology (HP:0012438)2.39550442
83Cholecystitis (HP:0001082)2.39550442
84Alkalosis (HP:0001948)2.35971148
85Proximal tubulopathy (HP:0000114)2.35263115
86Abnormal gallbladder morphology (HP:0012437)2.34750186
87Nephritis (HP:0000123)2.30626197
88Cholelithiasis (HP:0001081)2.30166877
89Vomiting (HP:0002013)2.28580528
90Abnormality of polysaccharide metabolism (HP:0011012)2.27898741
91Abnormality of glycosaminoglycan metabolism (HP:0004371)2.27898741
92Abnormality of mucopolysaccharide metabolism (HP:0011020)2.27898741
93Increased purine levels (HP:0004368)2.27850385
94Hyperuricemia (HP:0002149)2.27850385
95Abnormality of the Achilles tendon (HP:0005109)2.26648176
96Pancreatitis (HP:0001733)2.26348762
97Sensorimotor neuropathy (HP:0007141)2.25810736
98Stridor (HP:0010307)2.25594127
99Esophageal varix (HP:0002040)2.25130101
100Spinal cord compression (HP:0002176)2.24635477
101Reticulocytosis (HP:0001923)2.22090411
102Hypophosphatemia (HP:0002148)2.21398700
103Hyperinsulinemic hypoglycemia (HP:0000825)2.19655261
104Abnormal hair laboratory examination (HP:0003328)2.17805252
105Enlarged penis (HP:0000040)2.17310394
106Micronodular cirrhosis (HP:0001413)2.17211552
107Visceral angiomatosis (HP:0100761)2.16004063
108Pili torti (HP:0003777)2.14844787
109Brushfield spots (HP:0001088)2.14687696
110Hyperparathyroidism (HP:0000843)2.13379198
111Enlarged kidneys (HP:0000105)2.13359330
112Increased cerebral lipofuscin (HP:0011813)2.11976921
113Rickets (HP:0002748)2.10734135
114Abnormality of urine glucose concentration (HP:0011016)2.09841870
115Glycosuria (HP:0003076)2.09841870
116Abnormal urine phosphate concentration (HP:0012599)2.09825677
117Microglossia (HP:0000171)2.09161031
118Glomerulonephritis (HP:0000099)2.08758499
119Mitral stenosis (HP:0001718)2.08414925
120Hyperacusis (HP:0010780)2.07167625
121Widely patent fontanelles and sutures (HP:0004492)2.06804529
122Growth hormone excess (HP:0000845)2.06003696
123Hydroxyprolinuria (HP:0003080)2.05081325
124Abnormality of proline metabolism (HP:0010907)2.05081325
125Hyperactive renin-angiotensin system (HP:0000841)2.03983728
126Amyloidosis (HP:0011034)2.03964505
127Cerebral palsy (HP:0100021)2.02990969
128Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.02627636
129Curly hair (HP:0002212)2.02208025
130Abnormality of the gastric mucosa (HP:0004295)2.00273825
131Abnormal cartilage morphology (HP:0002763)1.99608089
132Menorrhagia (HP:0000132)1.97247253
133Abnormal enzyme/coenzyme activity (HP:0012379)1.96808245
134Abnormality of the gallbladder (HP:0005264)1.96301125
135Hypoparathyroidism (HP:0000829)1.95762153
136Breast carcinoma (HP:0003002)1.95175694
137Back pain (HP:0003418)1.94191992
138Seborrheic dermatitis (HP:0001051)1.94052572
139Opisthotonus (HP:0002179)1.94013702
140Hemorrhage of the eye (HP:0011885)1.94011075
141Long toe (HP:0010511)1.91360375
142Poikilocytosis (HP:0004447)1.91328639
143Abnormality of transition element cation homeostasis (HP:0011030)1.90207690
144Thrombophlebitis (HP:0004418)1.90002287
145Testicular atrophy (HP:0000029)1.89860830
146Gingival bleeding (HP:0000225)1.89601809
147Abnormality of the distal phalanges of the toes (HP:0010182)1.87837260
148Recurrent gram-negative bacterial infections (HP:0005420)1.86955682
149Hyperphosphaturia (HP:0003109)1.86565267
150Hemangiomatosis (HP:0007461)1.84375695
151Abnormality of vitamin metabolism (HP:0100508)1.83456394
152Prolonged neonatal jaundice (HP:0006579)1.83159616
153Bifid scrotum (HP:0000048)1.83090178
154Hyperglycemia (HP:0003074)1.82704910
155Increased serum ferritin (HP:0003281)1.81185248
156Abnormality of iron homeostasis (HP:0011031)1.81099669
157Congenital glaucoma (HP:0001087)1.80423850
158Abnormality of carpal bone ossification (HP:0006257)1.80082817
159Cervical subluxation (HP:0003308)1.78698925
160Dysostosis multiplex (HP:0000943)1.78549783
161Mildly elevated creatine phosphokinase (HP:0008180)1.78257826
162Achilles tendon contracture (HP:0001771)1.75917348

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.18055167
2ERN14.32407951
3FGFR44.03223227
4SIK13.70929352
5MUSK3.03082155
6MAPKAPK33.02943621
7TAOK32.98727003
8INSRR2.76580137
9MST1R2.45591275
10TRIB32.45178428
11RPS6KB22.39980771
12ERBB42.29805503
13PKN22.21576536
14SMG12.03598360
15SCYL22.00870777
16TESK11.94941751
17MAP2K41.89491895
18EEF2K1.83537183
19NME21.79316195
20FRK1.76950879
21PIK3CG1.73149682
22PTK61.69944044
23MAPK111.65371804
24FLT31.60865895
25WNK41.54680192
26EPHA21.52937461
27PDK41.50305955
28PDK31.50305955
29LATS11.43089899
30STK38L1.41008769
31PRKCI1.35196817
32TESK21.34430197
33NEK61.34347867
34ABL21.28500337
35MAP3K31.26866290
36TYK21.26651795
37DAPK21.26060699
38NEK91.23384499
39PINK11.22274746
40ILK1.20521522
41MAP2K31.19194004
42MAPK151.17040378
43MAP3K71.16951043
44PAK41.15440627
45KDR1.13898110
46MAP2K21.13690629
47MAP3K121.11880873
48MAP3K111.11318660
49GRK61.10553877
50CHUK1.03257759
51JAK21.02033707
52MAP2K61.01008870
53DYRK1B1.00515961
54PRKAA20.98359791
55MET0.96045863
56MAP3K100.94047236
57ERBB20.92624525
58WNK30.92457521
59EPHB10.90574419
60RPS6KA20.88488249
61TBK10.85847824
62NME10.83948333
63PRKCZ0.83906123
64PTK20.83693943
65RIPK10.82884209
66IRAK30.82358522
67FGFR20.80960698
68ICK0.79621298
69PDK20.78966310
70PDPK10.78837042
71SIK30.77753222
72MAP3K20.76028637
73PIM20.75325913
74CAMK2G0.74149171
75GSK3A0.69475391
76PRKAA10.68068580
77CAMKK10.67622703
78MAPK40.66477844
79TIE10.66457306
80TNK20.66271801
81MAP2K10.66095381
82PRKACG0.65957539
83MAP3K10.65759874
84JAK10.64658608
85CDK70.63019643
86CDK60.61559795
87PRKD20.60270677
88SGK30.58186079
89ARAF0.56166626
90MAPK120.56106654
91STK380.53079299
92PDK10.52711448
93STK390.51426270
94RPS6KL10.50233875
95RPS6KC10.50233875
96MAPKAPK20.47593980
97OXSR10.47554782
98EPHA30.47486397
99RPS6KB10.46929094
100HIPK20.45863694
101CSK0.45446198
102PRPF4B0.44863071
103TGFBR20.41915144
104RPS6KA60.40647547
105CAMK2B0.40639605
106CAMK2D0.40501857
107SGK4940.40386324
108SGK2230.40386324
109PRKD10.39758805
110AKT20.38364532
111MTOR0.38288071
112NEK10.38267990
113TAOK10.38230753
114IRAK40.37379203
115MAP3K50.36130739
116CAMK1D0.36106799
117GRK10.34973640
118RET0.34918126
119PRKG20.34259118
120CSF1R0.34112088
121PRKCQ0.32447332
122FGFR30.32257337
123VRK20.32139188
124SGK20.31788227
125PRKD30.31380715
126IRAK10.30951665
127CDK40.30748804
128PIK3CA0.29926529
129FER0.29749533
130MYLK0.29463465
131LRRK20.29270905
132IKBKE0.29176690
133IKBKB0.29044333
134LIMK10.28799327
135TAOK20.28477321
136MARK20.28307740
137MAP3K140.28178258
138KSR20.27826992
139PRKCA0.27467209
140MAP3K90.27011574
141IRAK20.26072936
142EIF2AK10.25554483
143PRKCG0.25371980
144DAPK10.25362539
145IGF1R0.24849049
146RPS6KA10.23787276
147MATK0.23757047
148LMTK20.23687329
149TLK10.22425724
150EGFR0.22373235
151CDC42BPA0.21667101
152MAPK80.19232190

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.20663055
2Nitrogen metabolism_Homo sapiens_hsa009103.39976305
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.39504852
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.26687512
5Arginine biosynthesis_Homo sapiens_hsa002202.95578879
6Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.70483306
7Tryptophan metabolism_Homo sapiens_hsa003802.67320252
8Fatty acid degradation_Homo sapiens_hsa000712.57717054
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.51453838
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.50370233
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.46785095
12Complement and coagulation cascades_Homo sapiens_hsa046102.44608282
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.34273136
14Butanoate metabolism_Homo sapiens_hsa006502.25132723
15Peroxisome_Homo sapiens_hsa041462.09933074
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.09117151
17Propanoate metabolism_Homo sapiens_hsa006402.05770639
18Histidine metabolism_Homo sapiens_hsa003401.88948349
19Chemical carcinogenesis_Homo sapiens_hsa052041.88552258
20Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.87992146
21PPAR signaling pathway_Homo sapiens_hsa033201.86090684
22Fatty acid metabolism_Homo sapiens_hsa012121.82784787
23Steroid hormone biosynthesis_Homo sapiens_hsa001401.76135904
24beta-Alanine metabolism_Homo sapiens_hsa004101.73314531
25Drug metabolism - other enzymes_Homo sapiens_hsa009831.69500957
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.68541892
27Sulfur metabolism_Homo sapiens_hsa009201.65986718
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.65698052
29Selenocompound metabolism_Homo sapiens_hsa004501.65696587
302-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.63345177
31Caffeine metabolism_Homo sapiens_hsa002321.60702014
32Retinol metabolism_Homo sapiens_hsa008301.59465082
33Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.56247276
34Bile secretion_Homo sapiens_hsa049761.55492232
35Pyruvate metabolism_Homo sapiens_hsa006201.53576093
36Phenylalanine metabolism_Homo sapiens_hsa003601.50816050
37Staphylococcus aureus infection_Homo sapiens_hsa051501.43192385
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.41569556
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.35060685
40Folate biosynthesis_Homo sapiens_hsa007901.33844938
41Tyrosine metabolism_Homo sapiens_hsa003501.33124128
42Fat digestion and absorption_Homo sapiens_hsa049751.33084978
43Maturity onset diabetes of the young_Homo sapiens_hsa049501.31218297
44Starch and sucrose metabolism_Homo sapiens_hsa005001.28943276
45Cyanoamino acid metabolism_Homo sapiens_hsa004601.24642300
46Carbon metabolism_Homo sapiens_hsa012001.24517388
47Fatty acid elongation_Homo sapiens_hsa000621.23777113
48Biosynthesis of amino acids_Homo sapiens_hsa012301.22939764
49ABC transporters_Homo sapiens_hsa020101.15277666
50Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.13963123
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.05621827
52Arginine and proline metabolism_Homo sapiens_hsa003301.03892098
53Sulfur relay system_Homo sapiens_hsa041221.02759403
54Steroid biosynthesis_Homo sapiens_hsa001001.02654127
55Vitamin digestion and absorption_Homo sapiens_hsa049770.98775670
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.94151766
57Sphingolipid metabolism_Homo sapiens_hsa006000.87403470
58Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.86385691
59Vitamin B6 metabolism_Homo sapiens_hsa007500.84912283
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.84428148
61Glutathione metabolism_Homo sapiens_hsa004800.83787811
62Glycerolipid metabolism_Homo sapiens_hsa005610.79392351
63Lysine degradation_Homo sapiens_hsa003100.78614105
64Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.74665351
65Pentose phosphate pathway_Homo sapiens_hsa000300.70027266
66Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.68963433
67Tight junction_Homo sapiens_hsa045300.66194117
68Vibrio cholerae infection_Homo sapiens_hsa051100.66013241
69Endometrial cancer_Homo sapiens_hsa052130.63862548
70Acute myeloid leukemia_Homo sapiens_hsa052210.63820534
71One carbon pool by folate_Homo sapiens_hsa006700.63007337
72Thyroid cancer_Homo sapiens_hsa052160.59233514
73Longevity regulating pathway - mammal_Homo sapiens_hsa042110.57019779
74VEGF signaling pathway_Homo sapiens_hsa043700.54948199
75Metabolic pathways_Homo sapiens_hsa011000.50962199
76Fatty acid biosynthesis_Homo sapiens_hsa000610.49655393
77Fructose and mannose metabolism_Homo sapiens_hsa000510.47298039
78Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.45610470
79mTOR signaling pathway_Homo sapiens_hsa041500.42155527
80alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38623771
81Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.37273972
82Choline metabolism in cancer_Homo sapiens_hsa052310.36899042
83N-Glycan biosynthesis_Homo sapiens_hsa005100.36188678
84Galactose metabolism_Homo sapiens_hsa000520.35284252
85ErbB signaling pathway_Homo sapiens_hsa040120.33781985
86Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32235438
87Linoleic acid metabolism_Homo sapiens_hsa005910.30897048
88Estrogen signaling pathway_Homo sapiens_hsa049150.29873075
89Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.29137615
90Prolactin signaling pathway_Homo sapiens_hsa049170.29048599
91Non-small cell lung cancer_Homo sapiens_hsa052230.28523040
92Prion diseases_Homo sapiens_hsa050200.25749380
93Insulin resistance_Homo sapiens_hsa049310.25286002
94Adipocytokine signaling pathway_Homo sapiens_hsa049200.22709358
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.22178766
96Glucagon signaling pathway_Homo sapiens_hsa049220.14077203
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.12006574
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.08385516
99AMPK signaling pathway_Homo sapiens_hsa041520.05142594
100Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.03593702
101Lysosome_Homo sapiens_hsa04142-0.2036656
102Other glycan degradation_Homo sapiens_hsa00511-0.2000627
103Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.1815454
104Bladder cancer_Homo sapiens_hsa05219-0.1716434
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1704294
106Hepatitis C_Homo sapiens_hsa05160-0.1698396
107Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1649729
108Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1541631
109Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1514185
110Protein digestion and absorption_Homo sapiens_hsa04974-0.1023008
111Insulin signaling pathway_Homo sapiens_hsa04910-0.0828102
112Thyroid hormone synthesis_Homo sapiens_hsa04918-0.0773494
113Regulation of autophagy_Homo sapiens_hsa04140-0.0707996
114Renin-angiotensin system_Homo sapiens_hsa04614-0.0699614
115Mineral absorption_Homo sapiens_hsa04978-0.0611255
116Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0539991
117Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.0438008
118Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0416742
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.0118226

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