STAT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.52727756
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.52727756
3antigen processing and presentation of endogenous antigen (GO:0019883)5.23250340
4positive regulation of interferon-alpha production (GO:0032727)4.82323707
5* response to type I interferon (GO:0034340)4.59540967
6* type I interferon signaling pathway (GO:0060337)4.58126516
7* cellular response to type I interferon (GO:0071357)4.58126516
8regulation of interferon-alpha production (GO:0032647)4.55267828
9negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.50796503
10negative regulation of cell killing (GO:0031342)4.50796503
11antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.42967119
12modulation by symbiont of host defense response (GO:0052031)4.22512011
13modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.22512011
14modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.22512011
15positive regulation by organism of defense response of other organism involved in symbiotic interact4.22512011
16modulation by symbiont of host immune response (GO:0052553)4.22512011
17positive regulation by symbiont of host defense response (GO:0052509)4.22512011
18response to interferon-alpha (GO:0035455)4.12945993
19regulation of interferon-beta biosynthetic process (GO:0045357)3.89501158
20positive regulation of gamma-delta T cell activation (GO:0046645)3.86138700
21positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.85613005
22negative regulation of interleukin-12 production (GO:0032695)3.72153664
23positive regulation of natural killer cell differentiation (GO:0032825)3.61709160
24detection of other organism (GO:0098543)3.57958813
25immunoglobulin mediated immune response (GO:0016064)3.51886039
26neutrophil activation involved in immune response (GO:0002283)3.49176540
27macrophage activation involved in immune response (GO:0002281)3.48147915
28detection of bacterium (GO:0016045)3.44900692
29interferon-gamma-mediated signaling pathway (GO:0060333)3.43368900
30regulation of RIG-I signaling pathway (GO:0039535)3.42998669
31detection of external biotic stimulus (GO:0098581)3.34984586
32positive regulation of interferon-beta production (GO:0032728)3.34389627
33response to host immune response (GO:0052572)3.26016615
34response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.26016615
35cellular response to virus (GO:0098586)3.24702036
36negative regulation of viral genome replication (GO:0045071)3.22878895
37cellular response to interferon-beta (GO:0035458)3.21951189
38NIK/NF-kappaB signaling (GO:0038061)3.20087962
39JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.17048989
40positive regulation of type 2 immune response (GO:0002830)3.16740029
41triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.16533979
42regulation of T cell tolerance induction (GO:0002664)3.16527692
43response to peptidoglycan (GO:0032494)3.15389203
44complement activation, alternative pathway (GO:0006957)3.13867555
45cellular response to interferon-alpha (GO:0035457)3.13501221
46regulation of interleukin-12 biosynthetic process (GO:0045075)3.09679223
47negative regulation of T cell mediated immunity (GO:0002710)3.09033995
48positive regulation of humoral immune response (GO:0002922)3.06286561
49regulation of B cell receptor signaling pathway (GO:0050855)3.05391892
50T-helper 1 type immune response (GO:0042088)3.04623542
51positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.03527419
52positive regulation of antigen processing and presentation (GO:0002579)3.03426003
53peptidyl-glutamic acid carboxylation (GO:0017187)3.02571522
54protein carboxylation (GO:0018214)3.02571522
55cellular response to exogenous dsRNA (GO:0071360)3.01603783
56regulation of dendritic cell antigen processing and presentation (GO:0002604)3.00457771
57response to interferon-beta (GO:0035456)3.00100181
58regulation of MHC class I biosynthetic process (GO:0045343)2.97394364
59* regulation of type I interferon-mediated signaling pathway (GO:0060338)2.96519213
60lipopolysaccharide-mediated signaling pathway (GO:0031663)2.95690090
61negative regulation of lymphocyte mediated immunity (GO:0002707)2.95050394
62response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.92789630
63response to host (GO:0075136)2.92789630
64response to host defenses (GO:0052200)2.92789630
65regulation of cholesterol storage (GO:0010885)2.90809020
66negative regulation of cytokine production involved in immune response (GO:0002719)2.90534238
67plasma lipoprotein particle clearance (GO:0034381)2.90412827
68regulation of type 2 immune response (GO:0002828)2.89300571
69cellular response to interferon-gamma (GO:0071346)2.88864661
70detection of biotic stimulus (GO:0009595)2.88845999
71regulation of tolerance induction (GO:0002643)2.88480518
72cellular extravasation (GO:0045123)2.85986426
73germinal center formation (GO:0002467)2.85561679
74phospholipid efflux (GO:0033700)2.85218858
75positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.83391731
76regulation of protein activation cascade (GO:2000257)2.82732464
77regulation of gamma-delta T cell activation (GO:0046643)2.81776344
78defense response to protozoan (GO:0042832)2.80247107
79tryptophan catabolic process (GO:0006569)2.79509041
80indole-containing compound catabolic process (GO:0042436)2.79509041
81indolalkylamine catabolic process (GO:0046218)2.79509041
82microglial cell activation (GO:0001774)2.79404823
83* defense response to virus (GO:0051607)2.78847986
84negative regulation of innate immune response (GO:0045824)2.77572600
85urea cycle (GO:0000050)2.77546934
86urea metabolic process (GO:0019627)2.77546934
87positive regulation of cellular amide metabolic process (GO:0034250)2.75696638
88natural killer cell mediated immunity (GO:0002228)2.74962825
89natural killer cell mediated cytotoxicity (GO:0042267)2.74962825
90regulation of activation of Janus kinase activity (GO:0010533)2.73946986
91granulocyte activation (GO:0036230)2.73945959
92positive regulation of interleukin-12 production (GO:0032735)2.73784887
93positive regulation of toll-like receptor signaling pathway (GO:0034123)2.73726823
94aromatic amino acid family catabolic process (GO:0009074)2.71918813
95kynurenine metabolic process (GO:0070189)2.71834102
96positive regulation of B cell differentiation (GO:0045579)2.71744462
97response to protozoan (GO:0001562)2.71274348
98low-density lipoprotein particle clearance (GO:0034383)2.70231536
99regulation of complement activation (GO:0030449)2.69961319
100negative regulation of leukocyte mediated immunity (GO:0002704)2.68720205
101positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.66154858
102positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.65792033
103regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.65380166
104tryptophan metabolic process (GO:0006568)2.65208660
105macrophage activation (GO:0042116)2.65188478
106production of molecular mediator involved in inflammatory response (GO:0002532)2.65016605
107regulation of gamma-delta T cell differentiation (GO:0045586)2.65012015
108regulation of hypersensitivity (GO:0002883)2.64568382
109T cell migration (GO:0072678)2.64233300
110response to muramyl dipeptide (GO:0032495)2.63979876
111I-kappaB phosphorylation (GO:0007252)2.63897940
112L-phenylalanine catabolic process (GO:0006559)2.63413511
113erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.63413511
114lymphocyte chemotaxis (GO:0048247)2.63410425
115growth hormone receptor signaling pathway (GO:0060396)2.63037831
116regulation of T-helper 1 cell differentiation (GO:0045625)2.62859272
117detection of molecule of bacterial origin (GO:0032490)2.62446332
118neutrophil activation (GO:0042119)2.62271605
119negative regulation of type 2 immune response (GO:0002829)2.62209364
120high-density lipoprotein particle remodeling (GO:0034375)2.62029650
121cellular response to ethanol (GO:0071361)2.61831441
122interferon-gamma secretion (GO:0072643)2.61576674
123leukocyte aggregation (GO:0070486)2.61425433
124positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.60881423
125phospholipid homeostasis (GO:0055091)2.60361099
126respiratory burst (GO:0045730)2.60220973
127regulation of T cell mediated cytotoxicity (GO:0001914)2.59569840
128antigen processing and presentation via MHC class Ib (GO:0002475)2.59408342
129negative regulation of bone resorption (GO:0045779)2.59328612
130negative regulation of lipid storage (GO:0010888)2.58471160
131regulation of antigen processing and presentation (GO:0002577)2.57044660
132negative thymic T cell selection (GO:0045060)2.57022239
133response to interleukin-15 (GO:0070672)2.56892749
134response to interferon-gamma (GO:0034341)2.56780421
135myeloid cell activation involved in immune response (GO:0002275)2.56497771
136regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.56153947
137regulation of T-helper 2 cell differentiation (GO:0045628)2.51055571
138positive regulation of defense response to virus by host (GO:0002230)2.49695105
139positive regulation of tolerance induction (GO:0002645)2.47796914
140B cell mediated immunity (GO:0019724)2.46577796
141negative T cell selection (GO:0043383)2.46142221
142negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.45824617
143negative regulation of T-helper cell differentiation (GO:0045623)2.44868643
144negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.44868643
145negative regulation of viral process (GO:0048525)2.42241951

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* IRF8_22096565_ChIP-ChIP_GC-B_Human6.69345121
2IRF1_21803131_ChIP-Seq_MONOCYTES_Human5.46666381
3IRF8_21731497_ChIP-ChIP_J774_Mouse5.32510330
4* ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.51487080
5* IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.95480647
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.66604410
7IRF8_27001747_Chip-Seq_BMDM_Mouse3.49168456
8* RXR_22158963_ChIP-Seq_LIVER_Mouse3.36182115
9PPARA_22158963_ChIP-Seq_LIVER_Mouse3.06453061
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.05206004
11EGR1_23403033_ChIP-Seq_LIVER_Mouse2.94870716
12* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.92242799
13STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.91728315
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.86563057
15LXR_22158963_ChIP-Seq_LIVER_Mouse2.83962358
16RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.67246686
17GATA1_22025678_ChIP-Seq_K562_Human2.57559327
18Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.50548956
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.39272899
20MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.37892913
21STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.30758799
22STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.29601041
23MYB_21317192_ChIP-Seq_ERMYB_Mouse2.13771541
24* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.12032947
25FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.10968360
26* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.07850304
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.98606814
28THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.97573859
29SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.88611067
30CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.87780847
31PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.77650115
32NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.74682156
33NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.74607609
34RUNX_20019798_ChIP-Seq_JUKART_Human1.67495745
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.61739058
36* MAF_26560356_Chip-Seq_TH1_Human1.60704615
37FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.51892575
38MYB_26560356_Chip-Seq_TH2_Human1.42273832
39MYB_26560356_Chip-Seq_TH1_Human1.40690458
40PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.40196306
41GATA2_21666600_ChIP-Seq_HMVEC_Human1.34419390
42SCL_19346495_ChIP-Seq_HPC-7_Human1.33607295
43PU_27001747_Chip-Seq_BMDM_Mouse1.33278942
44TP63_17297297_ChIP-ChIP_HaCaT_Human1.30242676
45SPI1_23127762_ChIP-Seq_K562_Human1.29222121
46CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.29148119
47LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.25176928
48CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.24341493
49RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.23223606
50VDR_24763502_ChIP-Seq_THP-1_Human1.22333067
51RUNX1_22412390_ChIP-Seq_EML_Mouse1.20399003
52CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20376662
53VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.20110661
54* SPI1_23547873_ChIP-Seq_NB4_Human1.18164018
55E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.17118301
56VDR_21846776_ChIP-Seq_THP-1_Human1.14414414
57VDR_24787735_ChIP-Seq_THP-1_Human1.13000622
58CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12686981
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.12017381
60* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08605448
61* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05291502
62GATA1_19941827_ChIP-Seq_MEL_Mouse1.05145350
63ELK3_25401928_ChIP-Seq_HUVEC_Human1.02309903
64* UTX_26944678_Chip-Seq_JUKART_Human1.01504264
65TRIM28_21343339_ChIP-Seq_HEK293_Human1.01417444
66TCF7_22412390_ChIP-Seq_EML_Mouse1.01369590
67KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01111195
68BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.01061910
69NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.00591113
70ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.00004896
71GATA3_27048872_Chip-Seq_THYMUS_Human0.99711620
72CLOCK_20551151_ChIP-Seq_293T_Human0.98937695
73CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97729803
74FOXA2_19822575_ChIP-Seq_HepG2_Human0.94597027
75GATA3_26560356_Chip-Seq_TH2_Human0.93936832
76CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.93586249
77KDM2B_26808549_Chip-Seq_SUP-B15_Human0.93255335
78CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.92413480
79GATA2_22383799_ChIP-Seq_G1ME_Mouse0.91846325
80ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.91162073
81FOXO3_23340844_ChIP-Seq_DLD1_Human0.90585033
82EGR1_19032775_ChIP-ChIP_M12_Human0.90383047
83KDM2B_26808549_Chip-Seq_DND41_Human0.87976538
84TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87921745
85CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.87420486
86IKZF1_21737484_ChIP-ChIP_HCT116_Human0.86996710
87GATA1_19941826_ChIP-Seq_K562_Human0.86159281
88TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.85801190
89MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.84664618
90PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.84286954
91JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.83216103
92GATA2_19941826_ChIP-Seq_K562_Human0.82436744
93LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.82319429
94CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.82302397
95MAF_26560356_Chip-Seq_TH2_Human0.81751469
96GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.81686992
97RARG_19884340_ChIP-ChIP_MEFs_Mouse0.81516544
98TP53_16413492_ChIP-PET_HCT116_Human0.80916460
99CJUN_26792858_Chip-Seq_BT549_Human0.80300367
100FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.80261729
101KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.80090455
102ESR2_21235772_ChIP-Seq_MCF-7_Human0.79551320
103VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.79525515
104SMRT_27268052_Chip-Seq_Bcells_Human0.79228992
105MYC_22102868_ChIP-Seq_BL_Human0.78314300
106TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.78259311
107NRF2_20460467_ChIP-Seq_MEFs_Mouse0.76634681
108NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.76634681
109* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76542937
110JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.76390093
111SOX2_20726797_ChIP-Seq_SW620_Human0.75763254
112BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.75462624
113LXR_22292898_ChIP-Seq_THP-1_Human0.73584824
114RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.72816948
115P63_26484246_Chip-Seq_KERATINOCYTES_Human0.72595955
116SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72303536
117TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.72210356
118GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72163826
119GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71887300

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0001835_abnormal_antigen_presentation3.72343692
2MP0002139_abnormal_hepatobiliary_system3.40771805
3MP0005360_urolithiasis3.14795455
4* MP0009785_altered_susceptibility_to3.11398709
5MP0003436_decreased_susceptibility_to2.87812343
6MP0004510_myositis2.80925515
7MP0009840_abnormal_foam_cell2.80366160
8MP0005387_immune_system_phenotype2.78000884
9MP0001790_abnormal_immune_system2.78000884
10MP0003303_peritoneal_inflammation2.75577265
11MP0000685_abnormal_immune_system2.75484308
12MP0006082_CNS_inflammation2.62962215
13MP0003724_increased_susceptibility_to2.53824842
14* MP0005025_abnormal_response_to2.49415855
15MP0005000_abnormal_immune_tolerance2.40303741
16MP0002419_abnormal_innate_immunity2.37973909
17MP0001800_abnormal_humoral_immune2.32239214
18MP0002148_abnormal_hypersensitivity_rea2.31980132
19MP0006054_spinal_hemorrhage2.29679288
20MP0005365_abnormal_bile_salt2.28549820
21MP0005085_abnormal_gallbladder_physiolo2.22530845
22MP0005671_abnormal_response_to2.20683821
23MP0002138_abnormal_hepatobiliary_system2.14660453
24MP0003191_abnormal_cellular_cholesterol2.12609892
25* MP0002452_abnormal_antigen_presenting2.10391987
26MP0002723_abnormal_immune_serum2.10226692
27MP0005058_abnormal_lysosome_morphology2.10177839
28MP0004947_skin_inflammation2.04689048
29MP0009764_decreased_sensitivity_to1.88244955
30MP0005083_abnormal_biliary_tract1.86341416
31MP0005464_abnormal_platelet_physiology1.85543252
32MP0003252_abnormal_bile_duct1.85471364
33MP0008469_abnormal_protein_level1.76295296
34MP0002254_reproductive_system_inflammat1.75731449
35MP0005503_abnormal_tendon_morphology1.74519622
36* MP0001819_abnormal_immune_cell1.74130269
37MP0008875_abnormal_xenobiotic_pharmacok1.73274763
38MP0001958_emphysema1.72338122
39* MP0002420_abnormal_adaptive_immunity1.70753832
40MP0010329_abnormal_lipoprotein_level1.67520584
41MP0001845_abnormal_inflammatory_respons1.63916742
42MP0005275_abnormal_skin_tensile1.63423662
43MP0002166_altered_tumor_susceptibility1.62947366
44MP0001533_abnormal_skeleton_physiology1.62797058
45MP0001853_heart_inflammation1.61694518
46MP0003279_aneurysm1.58474866
47MP0000604_amyloidosis1.57175893
48MP0004883_abnormal_blood_vessel1.56079752
49MP0010155_abnormal_intestine_physiology1.54917088
50MP0003300_gastrointestinal_ulcer1.51333639
51MP0003172_abnormal_lysosome_physiology1.46955447
52MP0002006_tumorigenesis1.46660003
53MP0000569_abnormal_digit_pigmentation1.44557366
54MP0000609_abnormal_liver_physiology1.44440229
55MP0002405_respiratory_system_inflammati1.40778552
56MP0008260_abnormal_autophagy1.35688457
57* MP0000716_abnormal_immune_system1.35651139
58* MP0002398_abnormal_bone_marrow1.29123186
59MP0003705_abnormal_hypodermis_morpholog1.29086287
60MP0009763_increased_sensitivity_to1.27543923
61MP0003448_altered_tumor_morphology1.26152331
62MP0005390_skeleton_phenotype1.24721324
63MP0003075_altered_response_to1.23042216
64MP0009278_abnormal_bone_marrow1.22040674
65MP0001542_abnormal_bone_strength1.21331153
66MP0005310_abnormal_salivary_gland1.21116313
67MP0003690_abnormal_glial_cell1.14852213
68MP0000689_abnormal_spleen_morphology1.12635754
69MP0001666_abnormal_nutrient_absorption1.12212759
70MP0000343_altered_response_to1.11686622
71MP0003453_abnormal_keratinocyte_physiol1.11671118
72MP0003045_fibrosis1.10756464
73* MP0002429_abnormal_blood_cell1.06820744
74MP0002998_abnormal_bone_remodeling1.06471636
75MP0005319_abnormal_enzyme/_coenzyme1.05595453
76MP0005397_hematopoietic_system_phenotyp1.05410988
77MP0001545_abnormal_hematopoietic_system1.05410988
78MP0002722_abnormal_immune_system1.01859212
79MP0005166_decreased_susceptibility_to1.00014461
80MP0001851_eye_inflammation0.99776565
81MP0002118_abnormal_lipid_homeostasis0.98970755
82MP0000015_abnormal_ear_pigmentation0.98469336
83MP0003866_abnormal_defecation0.96791729
84MP0005332_abnormal_amino_acid0.96124048
85MP0009333_abnormal_splenocyte_physiolog0.95101387
86MP0003656_abnormal_erythrocyte_physiolo0.94924814
87MP0005584_abnormal_enzyme/coenzyme_acti0.94862049
88MP0000371_diluted_coat_color0.92620721
89MP0003806_abnormal_nucleotide_metabolis0.91261583
90MP0003183_abnormal_peptide_metabolism0.91132861
91MP0000465_gastrointestinal_hemorrhage0.90869784
92MP0003763_abnormal_thymus_physiology0.90340212
93MP0003195_calcinosis0.90179308
94MP0001873_stomach_inflammation0.90153579
95MP0000920_abnormal_myelination0.90138191
96MP0008438_abnormal_cutaneous_collagen0.89836299
97MP0000598_abnormal_liver_morphology0.89406977
98MP0003795_abnormal_bone_structure0.88477237
99MP0003828_pulmonary_edema0.88032837
100MP0010307_abnormal_tumor_latency0.87696936
101MP0000858_altered_metastatic_potential0.87226661
102MP0003566_abnormal_cell_adhesion0.85898359
103MP0002168_other_aberrant_phenotype0.84770911
104MP0005023_abnormal_wound_healing0.84326407
105MP0003950_abnormal_plasma_membrane0.81662624
106MP0003091_abnormal_cell_migration0.81611046
107MP0000249_abnormal_blood_vessel0.78636018
108MP0003186_abnormal_redox_activity0.78322644
109MP0004381_abnormal_hair_follicle0.75772193
110MP0009643_abnormal_urine_homeostasis0.74770646
111MP0005164_abnormal_response_to0.74264696
112MP0002136_abnormal_kidney_physiology0.74256985
113MP0004782_abnormal_surfactant_physiolog0.73836547
114MP0001348_abnormal_lacrimal_gland0.73274422
115MP0002332_abnormal_exercise_endurance0.71431757
116MP0009765_abnormal_xenobiotic_induced0.71239221
117MP0004808_abnormal_hematopoietic_stem0.71223976
118MP0004019_abnormal_vitamin_homeostasis0.67997033
119MP0005451_abnormal_body_composition0.67763609
120MP0000767_abnormal_smooth_muscle0.66985691
121MP0005076_abnormal_cell_differentiation0.66350266
122MP0002933_joint_inflammation0.65972847
123MP0001881_abnormal_mammary_gland0.65916833
124MP0001663_abnormal_digestive_system0.65325609
125MP0008004_abnormal_stomach_pH0.64982742
126MP0000703_abnormal_thymus_morphology0.62901135

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)4.91120372
2Recurrent gram-negative bacterial infections (HP:0005420)4.65231117
3Recurrent bacterial skin infections (HP:0005406)4.45779265
4Recurrent abscess formation (HP:0002722)4.26642842
5Systemic lupus erythematosus (HP:0002725)4.26363490
6Autoimmune thrombocytopenia (HP:0001973)4.25328163
7Chronic otitis media (HP:0000389)3.96514707
8Myocardial infarction (HP:0001658)3.68327028
9Elevated erythrocyte sedimentation rate (HP:0003565)3.67378812
10Deep venous thrombosis (HP:0002625)3.64431850
11Abnormality of glycolipid metabolism (HP:0010969)3.58796002
12Abnormality of liposaccharide metabolism (HP:0010968)3.58796002
13Abnormality of glycosphingolipid metabolism (HP:0004343)3.58796002
14Gingival bleeding (HP:0000225)3.55273140
15Complement deficiency (HP:0004431)3.55219405
16Abnormality of macrophages (HP:0004311)3.49957345
17Abnormal delayed hypersensitivity skin test (HP:0002963)3.49904095
18Recurrent viral infections (HP:0004429)3.38448634
19Joint hemorrhage (HP:0005261)3.35576928
20Recurrent fungal infections (HP:0002841)3.35070384
21Myositis (HP:0100614)3.34572450
22Recurrent skin infections (HP:0001581)3.33596060
23Xanthomatosis (HP:0000991)3.27795254
24Mediastinal lymphadenopathy (HP:0100721)3.25542746
25Vasculitis (HP:0002633)3.23469077
26Orchitis (HP:0100796)3.19875158
27Intrahepatic cholestasis (HP:0001406)3.10664080
28Prolonged partial thromboplastin time (HP:0003645)3.08683834
29Spondylolisthesis (HP:0003302)3.08213297
30Gastrointestinal infarctions (HP:0005244)2.96842936
31Abnormality of monocarboxylic acid metabolism (HP:0010996)2.94256194
32Nasal polyposis (HP:0100582)2.92660402
33Glomerulonephritis (HP:0000099)2.91976485
34Dysostosis multiplex (HP:0000943)2.86616305
35Gingivitis (HP:0000230)2.85902455
36Abnormality of complement system (HP:0005339)2.85443300
37Optic neuritis (HP:0100653)2.81862516
38Retrobulbar optic neuritis (HP:0100654)2.81862516
39Keratoconjunctivitis (HP:0001096)2.79112847
40Abnormality of the nasal mucosa (HP:0000433)2.77967682
41Abnormality of aromatic amino acid family metabolism (HP:0004338)2.77402870
42Abnormality of the common coagulation pathway (HP:0010990)2.76966768
43Periodontitis (HP:0000704)2.72638455
44Epidermoid cyst (HP:0200040)2.71508843
45Interstitial pulmonary disease (HP:0006530)2.66021959
46Vacuolated lymphocytes (HP:0001922)2.65813718
47Hyperlipoproteinemia (HP:0010980)2.65423049
48Mitral stenosis (HP:0001718)2.62824735
49Nephritis (HP:0000123)2.60410011
50Abnormality of glycosaminoglycan metabolism (HP:0004371)2.58343129
51Abnormality of mucopolysaccharide metabolism (HP:0011020)2.58343129
52Abnormality of polysaccharide metabolism (HP:0011012)2.58343129
53Chronic mucocutaneous candidiasis (HP:0002728)2.57882317
54Recurrent cutaneous fungal infections (HP:0011370)2.57882317
55Recurrent bronchitis (HP:0002837)2.56607338
56T lymphocytopenia (HP:0005403)2.54642315
57Arterial thrombosis (HP:0004420)2.53695545
58Increased cerebral lipofuscin (HP:0011813)2.53311099
59Thick nail (HP:0001805)2.53119830
60Joint swelling (HP:0001386)2.51548649
61Urinary glycosaminoglycan excretion (HP:0003541)2.51457791
62Mucopolysacchariduria (HP:0008155)2.51457791
63Loss of speech (HP:0002371)2.50804732
64Pustule (HP:0200039)2.50644812
65Cellulitis (HP:0100658)2.50323423
66Basal ganglia calcification (HP:0002135)2.49340537
67Increased IgE level (HP:0003212)2.46797138
68Esophageal varix (HP:0002040)2.44792643
69Colitis (HP:0002583)2.43785202
70Abnormality of glutamine family amino acid metabolism (HP:0010902)2.40139700
71Hypergammaglobulinemia (HP:0010702)2.39512800
72Hemoptysis (HP:0002105)2.36983587
73Pulmonary infiltrates (HP:0002113)2.36678097
74Increased IgM level (HP:0003496)2.36556274
75Tetraparesis (HP:0002273)2.35967327
76Axonal loss (HP:0003447)2.34852944
77Encephalitis (HP:0002383)2.34488387
78Peritonitis (HP:0002586)2.33893109
79Spontaneous hematomas (HP:0007420)2.33748191
80Malnutrition (HP:0004395)2.31963396
81Amyloidosis (HP:0011034)2.31955581
82Hypobetalipoproteinemia (HP:0003563)2.31265725
83Abnormality of sulfur amino acid metabolism (HP:0004339)2.27865474
84Chronic obstructive pulmonary disease (HP:0006510)2.25540349
85Obstructive lung disease (HP:0006536)2.25540349
86Hypercholesterolemia (HP:0003124)2.24438202
87Stomatitis (HP:0010280)2.23979134
88Thrombophlebitis (HP:0004418)2.23157030
89Epistaxis (HP:0000421)2.22855169
90Increased neuronal autofluorescent lipopigment (HP:0002074)2.22761491
91Protrusio acetabuli (HP:0003179)2.21993379
92Spontaneous abortion (HP:0005268)2.21549315
93Hemorrhage of the eye (HP:0011885)2.20233224
94Absent frontal sinuses (HP:0002688)2.18877258
95Urticaria (HP:0001025)2.18628779
96Aortic aneurysm (HP:0004942)2.17770848
97Hematochezia (HP:0002573)2.16811396
98Episodic fever (HP:0001954)2.15608538
99Purpura (HP:0000979)2.15477840
100Anorexia (HP:0002039)2.14901523
101Abnormality of the pleura (HP:0002103)2.14739539
102Pulmonary embolism (HP:0002204)2.13778691
103Emphysema (HP:0002097)2.13637226
104Aortic dissection (HP:0002647)2.13016149
105Cervical subluxation (HP:0003308)2.12797347
106Increased serum ferritin (HP:0003281)2.08551048
107Dilatation of the ascending aorta (HP:0005111)2.08203859
108Osteomyelitis (HP:0002754)2.07903149
109Meningitis (HP:0001287)2.07772471
110Abnormality of iron homeostasis (HP:0011031)2.06676563
111Abnormality of the pericardium (HP:0001697)2.05326472
112Leukocytosis (HP:0001974)2.04677321
113Albinism (HP:0001022)2.02588953
114Keratoconjunctivitis sicca (HP:0001097)2.02083881
115Abnormality of the peritoneum (HP:0002585)2.01824752
116Osteolytic defects of the phalanges of the hand (HP:0009771)2.00654308
117Osteolytic defects of the hand bones (HP:0009699)2.00654308
118Prolonged bleeding time (HP:0003010)1.99650725
119Inflammation of the large intestine (HP:0002037)1.98584851
120Gangrene (HP:0100758)1.98495602
121Menorrhagia (HP:0000132)1.96851309
122Chronic sinusitis (HP:0011109)1.95752379
123Gastrointestinal stroma tumor (HP:0100723)1.95652243
124Gastrointestinal inflammation (HP:0004386)1.94855845
125Autoimmune hemolytic anemia (HP:0001890)1.94508364
126Abnormality of T cell number (HP:0011839)1.93958269
127Chest pain (HP:0100749)1.93186207
128Restrictive lung disease (HP:0002091)1.92544657
129Increased CSF protein (HP:0002922)1.91337214
130Acne (HP:0001061)1.90620319
131Agammaglobulinemia (HP:0004432)1.90119821
132Papilledema (HP:0001085)1.89047994
133Abnormality of T cells (HP:0002843)1.89015768
134Polycythemia (HP:0001901)1.88793800
135Eosinophilia (HP:0001880)1.88655253
136Petechiae (HP:0000967)1.88616973
137Skin nodule (HP:0200036)1.88358871
138Abnormality of the endocardium (HP:0004306)1.88208919
139Vascular tortuosity (HP:0004948)1.86724550
140Cheilitis (HP:0100825)1.85500527

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FGFR43.81824111
2* TYK23.62565351
3MAP3K143.62134490
4TBK13.41618161
5ERN13.37284504
6IKBKE3.25126563
7JAK33.21961433
8KIT2.79469961
9MAP4K12.78028644
10* JAK12.76769289
11RIPK42.46280993
12BLK2.31248850
13MAP3K132.24707696
14EPHB12.22731428
15IRAK32.18670371
16TAOK32.16435321
17IRAK42.07858676
18IKBKB1.92974752
19FGFR31.89253054
20EPHA31.74863452
21FRK1.74255345
22SIK11.73959882
23PRPF4B1.72987363
24CDC42BPA1.61275322
25DDR21.58050973
26CSK1.56461953
27TNK21.49321141
28GRK71.48202361
29CHUK1.47619775
30JAK21.46128703
31ZAP701.41650987
32MAP3K31.41008214
33TXK1.33408857
34SYK1.32623651
35CSF1R1.26847236
36SIK21.26584876
37HCK1.25012727
38BMPR21.22706119
39PTK61.20979450
40PRKD21.17907601
41BTK1.04673545
42PBK1.01345497
43STK31.00757412
44TRIB31.00308410
45MAPK71.00097950
46STK100.98344198
47HIPK20.98270921
48MAPK110.96672851
49CAMK1D0.94495314
50* LCK0.93422384
51PIM20.93137548
52RIPK10.92681268
53MATK0.91867776
54MAP3K100.90377178
55TGFBR20.89983433
56PTK2B0.85436845
57BMX0.85432747
58MARK30.84931073
59NEK90.84645117
60PIK3CG0.84429837
61FLT30.82505371
62PKN20.82076346
63LYN0.80451765
64MARK20.79250059
65RPS6KA40.78825195
66FER0.76628037
67LATS10.74419319
68ITK0.71837141
69ADRBK20.71689344
70PIM10.71443240
71CDK120.71317408
72FGFR20.68836902
73FES0.66968961
74TAOK10.66442150
75CAMK1G0.66386462
76PDGFRA0.65509653
77GRK60.65082745
78NLK0.65037572
79FGR0.64939758
80IRAK10.64689186
81LRRK20.62814415
82MAP2K60.62306688
83TAOK20.62074437
84MAP3K20.60976494
85EGFR0.60304173
86PRKCQ0.59769102
87NUAK10.59669495
88MAP3K60.58164156
89CDK60.56724578
90ABL10.55656310
91TTN0.55391692
92MYLK0.55323751
93MAP2K30.52251159
94TEC0.50838579
95MAP3K50.49626736
96DAPK20.49373990
97STK40.48255601
98MAP3K110.47237019
99INSRR0.46458944
100MST1R0.45822104
101MAPK120.44852214
102PRKD10.44729250
103SGK30.44687129
104TRPM70.43914471
105PAK30.43483859
106YES10.43231448
107AKT30.41911430
108MAP3K70.40858727
109PDK10.40625708
110PRKCH0.39929226
111PDGFRB0.39242849
112ABL20.38545944
113PRKAA20.38145904
114PDPK10.37893632
115RET0.37821532
116STK380.37729038
117SGK20.34331947
118ERBB40.34023953
119ACVR1B0.33765405
120ALK0.33467073
121PRKCD0.33145767
122EIF2AK20.32822043
123MELK0.32309451
124FYN0.31144152
125KDR0.30812136
126MAPK40.30722959
127MAP3K10.29086559
128SIK30.28999833
129PTK20.27288870
130SRC0.26687660
131IGF1R0.26063282
132ERBB20.24715144
133INSR0.23279340

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051503.30801355
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.76515833
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.66757213
4Leishmaniasis_Homo sapiens_hsa051402.39185364
5Complement and coagulation cascades_Homo sapiens_hsa046102.37776670
6Toll-like receptor signaling pathway_Homo sapiens_hsa046202.29185114
7Caffeine metabolism_Homo sapiens_hsa002322.23520619
8RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.22588354
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.17365675
10Nitrogen metabolism_Homo sapiens_hsa009102.05400008
11Arginine biosynthesis_Homo sapiens_hsa002202.05356368
12* Measles_Homo sapiens_hsa051621.99571356
13Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.84657483
14Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.81746765
15Allograft rejection_Homo sapiens_hsa053301.76257132
16* Influenza A_Homo sapiens_hsa051641.72744651
17* Osteoclast differentiation_Homo sapiens_hsa043801.71524646
18Intestinal immune network for IgA production_Homo sapiens_hsa046721.70530041
19Pertussis_Homo sapiens_hsa051331.63182669
20Graft-versus-host disease_Homo sapiens_hsa053321.59751904
21NOD-like receptor signaling pathway_Homo sapiens_hsa046211.56846121
22TNF signaling pathway_Homo sapiens_hsa046681.50661817
23Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.50138842
24Primary immunodeficiency_Homo sapiens_hsa053401.48919011
25Malaria_Homo sapiens_hsa051441.48096932
26B cell receptor signaling pathway_Homo sapiens_hsa046621.47445097
27Tryptophan metabolism_Homo sapiens_hsa003801.42709896
28Toxoplasmosis_Homo sapiens_hsa051451.40540020
29Tuberculosis_Homo sapiens_hsa051521.38168135
30African trypanosomiasis_Homo sapiens_hsa051431.37050759
31* Herpes simplex infection_Homo sapiens_hsa051681.35480609
32Legionellosis_Homo sapiens_hsa051341.33237414
33Pentose and glucuronate interconversions_Homo sapiens_hsa000401.31025984
34ABC transporters_Homo sapiens_hsa020101.23310399
35* Hepatitis C_Homo sapiens_hsa051601.18469362
36* Jak-STAT signaling pathway_Homo sapiens_hsa046301.17188492
37PPAR signaling pathway_Homo sapiens_hsa033201.16026181
38Fatty acid degradation_Homo sapiens_hsa000711.06550110
39Peroxisome_Homo sapiens_hsa041461.04793945
40Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.03381757
41Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.02065163
42Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.01133203
43Antigen processing and presentation_Homo sapiens_hsa046121.00161646
44Lysosome_Homo sapiens_hsa041420.99695537
45Apoptosis_Homo sapiens_hsa042100.96479954
46Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.91434510
47* Chemokine signaling pathway_Homo sapiens_hsa040620.90548157
48Hematopoietic cell lineage_Homo sapiens_hsa046400.89997446
49Rheumatoid arthritis_Homo sapiens_hsa053230.89922609
50Histidine metabolism_Homo sapiens_hsa003400.88604782
51Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88232417
52Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.87454804
53Dorso-ventral axis formation_Homo sapiens_hsa043200.84869441
54Adipocytokine signaling pathway_Homo sapiens_hsa049200.84481035
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81464288
56Asthma_Homo sapiens_hsa053100.80609887
57Bile secretion_Homo sapiens_hsa049760.80456392
58Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.80453534
59Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.80431972
60* Hepatitis B_Homo sapiens_hsa051610.78661577
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.76261605
62Salmonella infection_Homo sapiens_hsa051320.76187003
63Lysine degradation_Homo sapiens_hsa003100.75580638
64Prolactin signaling pathway_Homo sapiens_hsa049170.74431172
65Vitamin digestion and absorption_Homo sapiens_hsa049770.73931506
66Steroid hormone biosynthesis_Homo sapiens_hsa001400.72204055
67Acute myeloid leukemia_Homo sapiens_hsa052210.71210691
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.70387506
69Amoebiasis_Homo sapiens_hsa051460.69758088
70Chemical carcinogenesis_Homo sapiens_hsa052040.69708457
71Insulin resistance_Homo sapiens_hsa049310.68153372
72T cell receptor signaling pathway_Homo sapiens_hsa046600.68074959
73Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67768185
74Drug metabolism - other enzymes_Homo sapiens_hsa009830.66337581
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.65887892
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.65646909
77Starch and sucrose metabolism_Homo sapiens_hsa005000.65316891
78Viral myocarditis_Homo sapiens_hsa054160.65309843
79Retinol metabolism_Homo sapiens_hsa008300.62981768
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.62939775
81Steroid biosynthesis_Homo sapiens_hsa001000.62703357
82Prion diseases_Homo sapiens_hsa050200.62471034
83Shigellosis_Homo sapiens_hsa051310.61515462
84Type I diabetes mellitus_Homo sapiens_hsa049400.61140341
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.59689540
86Phagosome_Homo sapiens_hsa041450.58959423
87Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58465045
88Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.57413535
89Phospholipase D signaling pathway_Homo sapiens_hsa040720.57047868
90Autoimmune thyroid disease_Homo sapiens_hsa053200.55714340
91Fatty acid metabolism_Homo sapiens_hsa012120.55316547
92Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53738443
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.53213286
94beta-Alanine metabolism_Homo sapiens_hsa004100.53013857
95Phenylalanine metabolism_Homo sapiens_hsa003600.52974077
96Chronic myeloid leukemia_Homo sapiens_hsa052200.49915368
97Sphingolipid signaling pathway_Homo sapiens_hsa040710.49724863
98VEGF signaling pathway_Homo sapiens_hsa043700.49442739
99Selenocompound metabolism_Homo sapiens_hsa004500.49123847
100Fat digestion and absorption_Homo sapiens_hsa049750.49047058
101Sphingolipid metabolism_Homo sapiens_hsa006000.47044989
102FoxO signaling pathway_Homo sapiens_hsa040680.46654096
103Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.46429474
104Endocytosis_Homo sapiens_hsa041440.45552668
105Neurotrophin signaling pathway_Homo sapiens_hsa047220.45508561
106Non-small cell lung cancer_Homo sapiens_hsa052230.44445045
107Leukocyte transendothelial migration_Homo sapiens_hsa046700.43755310
108GnRH signaling pathway_Homo sapiens_hsa049120.43141804
109Type II diabetes mellitus_Homo sapiens_hsa049300.42984297
110Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.42260888
111Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.41900467
112Phosphatidylinositol signaling system_Homo sapiens_hsa040700.41609960
113Pancreatic cancer_Homo sapiens_hsa052120.40686526
114mTOR signaling pathway_Homo sapiens_hsa041500.40516247
115Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40506039
116Sulfur relay system_Homo sapiens_hsa041220.39885126
117Notch signaling pathway_Homo sapiens_hsa043300.39705342
118Inositol phosphate metabolism_Homo sapiens_hsa005620.39437393
119Other glycan degradation_Homo sapiens_hsa005110.39217203
120Focal adhesion_Homo sapiens_hsa045100.38420533
121Proteoglycans in cancer_Homo sapiens_hsa052050.38305881
122Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36766350
123Choline metabolism in cancer_Homo sapiens_hsa052310.35142040
124Small cell lung cancer_Homo sapiens_hsa052220.33721728
125Platelet activation_Homo sapiens_hsa046110.33674322
126Prostate cancer_Homo sapiens_hsa052150.33043204
127Renal cell carcinoma_Homo sapiens_hsa052110.28331936
128Epstein-Barr virus infection_Homo sapiens_hsa051690.28267447
129Transcriptional misregulation in cancer_Homo sapiens_hsa052020.27615025
130HTLV-I infection_Homo sapiens_hsa051660.26520178
131Arachidonic acid metabolism_Homo sapiens_hsa005900.26333349
132MAPK signaling pathway_Homo sapiens_hsa040100.24159632

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »