Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.50834237 |
2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.50834237 |
3 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.31674374 |
4 | negative regulation of cell killing (GO:0031342) | 4.09321310 |
5 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.09321310 |
6 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.83004962 |
7 | * JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.72357898 |
8 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.57283512 |
9 | detection of other organism (GO:0098543) | 3.46837749 |
10 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.31580557 |
11 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.31580557 |
12 | modulation by symbiont of host immune response (GO:0052553) | 3.31580557 |
13 | positive regulation by symbiont of host defense response (GO:0052509) | 3.31580557 |
14 | modulation by symbiont of host defense response (GO:0052031) | 3.31580557 |
15 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.31580557 |
16 | detection of bacterium (GO:0016045) | 3.28751331 |
17 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.27113330 |
18 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.26628740 |
19 | germinal center formation (GO:0002467) | 3.26490878 |
20 | detection of molecule of bacterial origin (GO:0032490) | 3.20860146 |
21 | NIK/NF-kappaB signaling (GO:0038061) | 3.16885168 |
22 | macrophage activation involved in immune response (GO:0002281) | 3.14909433 |
23 | detection of external biotic stimulus (GO:0098581) | 3.14475824 |
24 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.12941611 |
25 | regulation of gamma-delta T cell activation (GO:0046643) | 3.06328535 |
26 | negative regulation of interleukin-12 production (GO:0032695) | 2.98220216 |
27 | response to type I interferon (GO:0034340) | 2.95870586 |
28 | type I interferon signaling pathway (GO:0060337) | 2.87900848 |
29 | cellular response to type I interferon (GO:0071357) | 2.87900848 |
30 | regulation of natural killer cell differentiation (GO:0032823) | 2.86089502 |
31 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.80076053 |
32 | hemidesmosome assembly (GO:0031581) | 2.77059282 |
33 | positive regulation of p38MAPK cascade (GO:1900745) | 2.76925447 |
34 | response to peptidoglycan (GO:0032494) | 2.75375962 |
35 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.75261784 |
36 | detection of biotic stimulus (GO:0009595) | 2.74888094 |
37 | positive regulation of histone deacetylation (GO:0031065) | 2.73951845 |
38 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.70462548 |
39 | * growth hormone receptor signaling pathway (GO:0060396) | 2.69582611 |
40 | regulation of cholesterol homeostasis (GO:2000188) | 2.67353225 |
41 | cellular extravasation (GO:0045123) | 2.66447995 |
42 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.65353375 |
43 | positive thymic T cell selection (GO:0045059) | 2.64114175 |
44 | negative regulation of fatty acid transport (GO:2000192) | 2.63849395 |
45 | skin morphogenesis (GO:0043589) | 2.63118028 |
46 | valine metabolic process (GO:0006573) | 2.60721780 |
47 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.60143436 |
48 | cellular response to interleukin-15 (GO:0071350) | 2.58897654 |
49 | response to interleukin-15 (GO:0070672) | 2.57062067 |
50 | tolerance induction (GO:0002507) | 2.56142908 |
51 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.55636678 |
52 | regulation of tolerance induction (GO:0002643) | 2.55161434 |
53 | positive regulation of tolerance induction (GO:0002645) | 2.55002537 |
54 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.54385341 |
55 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.52359445 |
56 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.51787361 |
57 | low-density lipoprotein particle clearance (GO:0034383) | 2.51780289 |
58 | neutrophil activation involved in immune response (GO:0002283) | 2.50029579 |
59 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.49677214 |
60 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.47796699 |
61 | response to laminar fluid shear stress (GO:0034616) | 2.47370454 |
62 | regulation of response to interferon-gamma (GO:0060330) | 2.46988084 |
63 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.46294539 |
64 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.46274488 |
65 | response to host (GO:0075136) | 2.46274488 |
66 | response to host defenses (GO:0052200) | 2.46274488 |
67 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.46170549 |
68 | response to host immune response (GO:0052572) | 2.45074319 |
69 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.45074319 |
70 | negative regulation of T cell mediated immunity (GO:0002710) | 2.44690838 |
71 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.44664356 |
72 | regulation of cholesterol storage (GO:0010885) | 2.43777374 |
73 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.42780011 |
74 | * JAK-STAT cascade (GO:0007259) | 2.42263743 |
75 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.42030179 |
76 | regulation of T cell tolerance induction (GO:0002664) | 2.41548201 |
77 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.41187185 |
78 | protein carboxylation (GO:0018214) | 2.40834926 |
79 | peptidyl-glutamic acid carboxylation (GO:0017187) | 2.40834926 |
80 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.40283449 |
81 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.40087238 |
82 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.38449127 |
83 | regulation of regulatory T cell differentiation (GO:0045589) | 2.38246815 |
84 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.37282928 |
85 | regulation of necroptotic process (GO:0060544) | 2.36576908 |
86 | response to muramyl dipeptide (GO:0032495) | 2.36565075 |
87 | COPI coating of Golgi vesicle (GO:0048205) | 2.34007946 |
88 | Golgi transport vesicle coating (GO:0048200) | 2.34007946 |
89 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.33923655 |
90 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.33905568 |
91 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.33027354 |
92 | negative regulation of innate immune response (GO:0045824) | 2.32965390 |
93 | thymic T cell selection (GO:0045061) | 2.32834111 |
94 | macrophage activation (GO:0042116) | 2.32726582 |
95 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.32556149 |
96 | negative thymic T cell selection (GO:0045060) | 2.32360248 |
97 | negative regulation of lipid storage (GO:0010888) | 2.32064112 |
98 | positive regulation of natural killer cell activation (GO:0032816) | 2.31807367 |
99 | negative regulation of humoral immune response (GO:0002921) | 2.31783838 |
100 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.31158275 |
101 | positive regulation of type 2 immune response (GO:0002830) | 2.30915177 |
102 | negative regulation of protein autophosphorylation (GO:0031953) | 2.30273552 |
103 | regulation of extracellular matrix disassembly (GO:0010715) | 2.29433195 |
104 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 2.28741914 |
105 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.28475911 |
106 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.28475911 |
107 | negative regulation of complement activation (GO:0045916) | 2.27361975 |
108 | surfactant homeostasis (GO:0043129) | 2.26871860 |
109 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.26679835 |
110 | negative T cell selection (GO:0043383) | 2.26178536 |
111 | T-helper 1 type immune response (GO:0042088) | 2.25720737 |
112 | cell adhesion mediated by integrin (GO:0033627) | 2.25668095 |
113 | positive regulation of antigen processing and presentation (GO:0002579) | 2.24740410 |
114 | tyrosine phosphorylation of STAT protein (GO:0007260) | 2.22043883 |
115 | protein localization to endosome (GO:0036010) | 2.21668101 |
116 | establishment of endothelial barrier (GO:0061028) | 2.21357626 |
117 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.21160022 |
118 | regulation of type 2 immune response (GO:0002828) | 2.20490270 |
119 | positive regulation of interferon-alpha production (GO:0032727) | 2.20249912 |
120 | myeloid dendritic cell differentiation (GO:0043011) | 2.19980181 |
121 | * cellular response to growth hormone stimulus (GO:0071378) | 2.19873250 |
122 | positive regulation of cholesterol efflux (GO:0010875) | 2.19854477 |
123 | negative regulation of type 2 immune response (GO:0002829) | 2.19396602 |
124 | response to interferon-alpha (GO:0035455) | 2.17775343 |
125 | negative regulation of protein activation cascade (GO:2000258) | 2.17719511 |
126 | apoptotic cell clearance (GO:0043277) | 2.16240485 |
127 | mannose metabolic process (GO:0006013) | 2.15929140 |
128 | positive regulation of receptor recycling (GO:0001921) | 2.15701604 |
129 | regulation of antigen processing and presentation (GO:0002577) | 2.15452289 |
130 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.15392742 |
131 | defense response to protozoan (GO:0042832) | 2.14545595 |
132 | regulation of interferon-alpha production (GO:0032647) | 2.13792252 |
133 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.13246362 |
134 | cellular response to vitamin D (GO:0071305) | 2.12879757 |
135 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.12811399 |
136 | positive regulation of humoral immune response (GO:0002922) | 2.11637833 |
137 | negative regulation of interleukin-6 production (GO:0032715) | 2.11559974 |
138 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.11495269 |
139 | dendritic cell chemotaxis (GO:0002407) | 2.11390736 |
140 | hepatocyte apoptotic process (GO:0097284) | 2.11044495 |
141 | positive regulation of interleukin-2 production (GO:0032743) | 2.10946435 |
142 | positive regulation of cholesterol transport (GO:0032376) | 2.10459904 |
143 | positive regulation of sterol transport (GO:0032373) | 2.10459904 |
144 | immunoglobulin mediated immune response (GO:0016064) | 2.09362013 |
145 | cytokine secretion (GO:0050663) | 2.08928339 |
146 | interleukin-1-mediated signaling pathway (GO:0070498) | 2.08205136 |
147 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.07514672 |
148 | positive regulation of B cell differentiation (GO:0045579) | 2.07147978 |
149 | gland morphogenesis (GO:0022612) | 2.06394675 |
150 | leukocyte aggregation (GO:0070486) | 2.06038692 |
151 | regulation of p38MAPK cascade (GO:1900744) | 2.05739494 |
152 | response to protozoan (GO:0001562) | 2.05446330 |
153 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.03975256 |
154 | negative regulation of bone resorption (GO:0045779) | 2.02199247 |
155 | regulation of natural killer cell activation (GO:0032814) | 2.01283019 |
156 | cellular response to vitamin (GO:0071295) | 2.00127214 |
157 | cellular response to interferon-alpha (GO:0035457) | 1.99843422 |
158 | virion attachment to host cell (GO:0019062) | 1.99602559 |
159 | adhesion of symbiont to host cell (GO:0044650) | 1.99602559 |
160 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 1.98869540 |
161 | natural killer cell differentiation (GO:0001779) | 1.98489382 |
162 | T cell selection (GO:0045058) | 1.98387383 |
163 | regulation of natural killer cell mediated immunity (GO:0002715) | 1.98379839 |
164 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 1.98379839 |
165 | vascular endothelial growth factor signaling pathway (GO:0038084) | 1.98336231 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.40404304 |
2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.96649886 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.87763455 |
4 | * STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.39055982 |
5 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.35731210 |
6 | * ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.87910286 |
7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.80046951 |
8 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.58574574 |
9 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.40921448 |
10 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.40793739 |
11 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.30417196 |
12 | * EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.25934842 |
13 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.25091194 |
14 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.23108515 |
15 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.17710475 |
16 | * STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.15625699 |
17 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.13270020 |
18 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.13110828 |
19 | * CLOCK_20551151_ChIP-Seq_293T_Human | 2.13081492 |
20 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.12931514 |
21 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.12289280 |
22 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.09805090 |
23 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.05814408 |
24 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.00540042 |
25 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.00482084 |
26 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.00135807 |
27 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.96647481 |
28 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.88077996 |
29 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.87010183 |
30 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.85072513 |
31 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.81380832 |
32 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.78999672 |
33 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.75698679 |
34 | MAF_26560356_Chip-Seq_TH1_Human | 1.73799318 |
35 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.71536426 |
36 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.71354655 |
37 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.71242550 |
38 | GATA1_22025678_ChIP-Seq_K562_Human | 1.70068335 |
39 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.67249493 |
40 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.65815515 |
41 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.64346826 |
42 | * MYB_26560356_Chip-Seq_TH2_Human | 1.59980153 |
43 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.57533585 |
44 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.55677402 |
45 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.51080474 |
46 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.50546687 |
47 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.47174850 |
48 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.46478975 |
49 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.45548665 |
50 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.45004224 |
51 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.42343106 |
52 | MYB_26560356_Chip-Seq_TH1_Human | 1.41136501 |
53 | MYC_22102868_ChIP-Seq_BL_Human | 1.40238482 |
54 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.39652820 |
55 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.38324730 |
56 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.37322117 |
57 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.37268831 |
58 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.36242140 |
59 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.35982744 |
60 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.33044487 |
61 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.33044487 |
62 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.30574442 |
63 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.30153267 |
64 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.28881378 |
65 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.28503378 |
66 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.28209830 |
67 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.27762205 |
68 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.24558458 |
69 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.23581574 |
70 | UTX_26944678_Chip-Seq_JUKART_Human | 1.23529548 |
71 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.22608255 |
72 | * EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.22131534 |
73 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.20804590 |
74 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.20740338 |
75 | * SPI1_23127762_ChIP-Seq_K562_Human | 1.18025506 |
76 | CJUN_26792858_Chip-Seq_BT549_Human | 1.17217127 |
77 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.14362210 |
78 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.14110505 |
79 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.13866950 |
80 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.13296792 |
81 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.12904326 |
82 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.12418506 |
83 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.12418506 |
84 | * SOX2_20726797_ChIP-Seq_SW620_Human | 1.11113175 |
85 | * RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10631389 |
86 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.10283191 |
87 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09918814 |
88 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.09804824 |
89 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09504295 |
90 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.09242068 |
91 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.08709044 |
92 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.08478808 |
93 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.08310416 |
94 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.08000306 |
95 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.07206506 |
96 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.06124593 |
97 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.05870387 |
98 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.04389809 |
99 | MAF_26560356_Chip-Seq_TH2_Human | 1.03995218 |
100 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.03787847 |
101 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.03565264 |
102 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.02739183 |
103 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.02672474 |
104 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.01772577 |
105 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.00651516 |
106 | GATA2_19941826_ChIP-Seq_K562_Human | 1.00298116 |
107 | * FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.00000352 |
108 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.99884706 |
109 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99258703 |
110 | GATA1_19941826_ChIP-Seq_K562_Human | 0.98575702 |
111 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.97444820 |
112 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96103139 |
113 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.95969364 |
114 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.95655947 |
115 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.95647292 |
116 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.95342427 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002254_reproductive_system_inflammat | 2.81540107 |
2 | MP0001835_abnormal_antigen_presentation | 2.45910251 |
3 | MP0003436_decreased_susceptibility_to | 2.39356648 |
4 | MP0000685_abnormal_immune_system | 2.39138713 |
5 | MP0003724_increased_susceptibility_to | 2.30925511 |
6 | MP0003303_peritoneal_inflammation | 2.27007181 |
7 | MP0003705_abnormal_hypodermis_morpholog | 2.25492771 |
8 | MP0002877_abnormal_melanocyte_morpholog | 2.25086846 |
9 | MP0008438_abnormal_cutaneous_collagen | 2.24349801 |
10 | MP0005451_abnormal_body_composition | 2.24017876 |
11 | * MP0003300_gastrointestinal_ulcer | 2.19327266 |
12 | MP0001790_abnormal_immune_system | 2.18122928 |
13 | MP0005387_immune_system_phenotype | 2.18122928 |
14 | MP0004510_myositis | 2.08013958 |
15 | MP0009785_altered_susceptibility_to | 1.97807553 |
16 | MP0005275_abnormal_skin_tensile | 1.97673733 |
17 | MP0002138_abnormal_hepatobiliary_system | 1.96073800 |
18 | MP0009840_abnormal_foam_cell | 1.87013061 |
19 | MP0003191_abnormal_cellular_cholesterol | 1.86796573 |
20 | MP0004947_skin_inflammation | 1.86782973 |
21 | MP0005000_abnormal_immune_tolerance | 1.76975398 |
22 | * MP0003566_abnormal_cell_adhesion | 1.72611529 |
23 | MP0001800_abnormal_humoral_immune | 1.71377086 |
24 | MP0002166_altered_tumor_susceptibility | 1.68645823 |
25 | MP0001533_abnormal_skeleton_physiology | 1.60295391 |
26 | * MP0005025_abnormal_response_to | 1.58884507 |
27 | * MP0002419_abnormal_innate_immunity | 1.54533904 |
28 | MP0005671_abnormal_response_to | 1.51727765 |
29 | MP0002148_abnormal_hypersensitivity_rea | 1.51715778 |
30 | * MP0002452_abnormal_antigen_presenting | 1.50453514 |
31 | MP0002933_joint_inflammation | 1.50378130 |
32 | MP0009278_abnormal_bone_marrow | 1.49652626 |
33 | * MP0002723_abnormal_immune_serum | 1.48185171 |
34 | MP0003279_aneurysm | 1.46462649 |
35 | * MP0010155_abnormal_intestine_physiology | 1.45409324 |
36 | * MP0005023_abnormal_wound_healing | 1.43447481 |
37 | MP0008260_abnormal_autophagy | 1.41029010 |
38 | * MP0003763_abnormal_thymus_physiology | 1.39885717 |
39 | MP0001853_heart_inflammation | 1.37997962 |
40 | MP0002405_respiratory_system_inflammati | 1.37716906 |
41 | MP0002060_abnormal_skin_morphology | 1.36994916 |
42 | MP0008004_abnormal_stomach_pH | 1.35980273 |
43 | MP0006082_CNS_inflammation | 1.35686060 |
44 | MP0005464_abnormal_platelet_physiology | 1.31799466 |
45 | * MP0003453_abnormal_keratinocyte_physiol | 1.31291974 |
46 | MP0001873_stomach_inflammation | 1.31096085 |
47 | MP0002006_tumorigenesis | 1.30155529 |
48 | MP0005076_abnormal_cell_differentiation | 1.29832389 |
49 | * MP0001819_abnormal_immune_cell | 1.29460983 |
50 | * MP0002420_abnormal_adaptive_immunity | 1.29188489 |
51 | MP0005164_abnormal_response_to | 1.28702303 |
52 | * MP0001845_abnormal_inflammatory_respons | 1.28316415 |
53 | MP0003172_abnormal_lysosome_physiology | 1.27231579 |
54 | MP0001958_emphysema | 1.26715278 |
55 | MP0001348_abnormal_lacrimal_gland | 1.25782281 |
56 | MP0003075_altered_response_to | 1.22926402 |
57 | MP0010234_abnormal_vibrissa_follicle | 1.21268955 |
58 | MP0003183_abnormal_peptide_metabolism | 1.20268605 |
59 | MP0002998_abnormal_bone_remodeling | 1.19947958 |
60 | MP0003828_pulmonary_edema | 1.17608922 |
61 | MP0001851_eye_inflammation | 1.16828627 |
62 | MP0005360_urolithiasis | 1.15312598 |
63 | MP0005058_abnormal_lysosome_morphology | 1.14509051 |
64 | MP0010368_abnormal_lymphatic_system | 1.14089857 |
65 | MP0003252_abnormal_bile_duct | 1.11975834 |
66 | MP0009764_decreased_sensitivity_to | 1.10814014 |
67 | MP0005166_decreased_susceptibility_to | 1.09829525 |
68 | * MP0003448_altered_tumor_morphology | 1.08157293 |
69 | * MP0008469_abnormal_protein_level | 1.07183080 |
70 | * MP0000609_abnormal_liver_physiology | 1.06831303 |
71 | MP0004883_abnormal_blood_vessel | 1.06694798 |
72 | * MP0003091_abnormal_cell_migration | 1.05678966 |
73 | MP0000343_altered_response_to | 1.04785798 |
74 | MP0001881_abnormal_mammary_gland | 1.04256353 |
75 | MP0005365_abnormal_bile_salt | 1.03498105 |
76 | MP0005409_darkened_coat_color | 1.01646456 |
77 | * MP0000716_abnormal_immune_system | 1.00538491 |
78 | MP0000604_amyloidosis | 0.99152493 |
79 | MP0002139_abnormal_hepatobiliary_system | 0.98878574 |
80 | MP0005310_abnormal_salivary_gland | 0.96693253 |
81 | MP0000767_abnormal_smooth_muscle | 0.95408878 |
82 | MP0005390_skeleton_phenotype | 0.95251515 |
83 | MP0004185_abnormal_adipocyte_glucose | 0.94067849 |
84 | MP0004858_abnormal_nervous_system | 0.93972201 |
85 | * MP0003045_fibrosis | 0.93948336 |
86 | MP0005083_abnormal_biliary_tract | 0.93298823 |
87 | * MP0002398_abnormal_bone_marrow | 0.92521282 |
88 | MP0006054_spinal_hemorrhage | 0.91519547 |
89 | MP0004264_abnormal_extraembryonic_tissu | 0.90082883 |
90 | * MP0010352_gastrointestinal_tract_polyps | 0.89639882 |
91 | * MP0001216_abnormal_epidermal_layer | 0.89424668 |
92 | MP0001545_abnormal_hematopoietic_system | 0.88598648 |
93 | MP0005397_hematopoietic_system_phenotyp | 0.88598648 |
94 | MP0004808_abnormal_hematopoietic_stem | 0.88399102 |
95 | MP0004381_abnormal_hair_follicle | 0.88016566 |
96 | MP0000689_abnormal_spleen_morphology | 0.87557263 |
97 | MP0002132_abnormal_respiratory_system | 0.86860138 |
98 | MP0002796_impaired_skin_barrier | 0.86820415 |
99 | MP0003656_abnormal_erythrocyte_physiolo | 0.86663911 |
100 | MP0000249_abnormal_blood_vessel | 0.86537543 |
101 | MP0009333_abnormal_splenocyte_physiolog | 0.86350130 |
102 | MP0004782_abnormal_surfactant_physiolog | 0.85557171 |
103 | MP0001243_abnormal_dermal_layer | 0.85540874 |
104 | * MP0000858_altered_metastatic_potential | 0.85301914 |
105 | MP0005666_abnormal_adipose_tissue | 0.85301431 |
106 | MP0003690_abnormal_glial_cell | 0.84134609 |
107 | MP0003329_amyloid_beta_deposits | 0.83371638 |
108 | MP0005375_adipose_tissue_phenotype | 0.82290407 |
109 | * MP0009643_abnormal_urine_homeostasis | 0.80255899 |
110 | MP0005085_abnormal_gallbladder_physiolo | 0.80208836 |
111 | MP0000733_abnormal_muscle_development | 0.80077259 |
112 | MP0008961_abnormal_basal_metabolism | 0.79381549 |
113 | MP0001879_abnormal_lymphatic_vessel | 0.79149931 |
114 | * MP0002429_abnormal_blood_cell | 0.78671388 |
115 | MP0000465_gastrointestinal_hemorrhage | 0.78553216 |
116 | MP0001849_ear_inflammation | 0.78338360 |
117 | MP0002396_abnormal_hematopoietic_system | 0.77405697 |
118 | * MP0009763_increased_sensitivity_to | 0.77390427 |
119 | * MP0002722_abnormal_immune_system | 0.76671969 |
120 | * MP0003795_abnormal_bone_structure | 0.76024743 |
121 | * MP0003866_abnormal_defecation | 0.75709831 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myocardial infarction (HP:0001658) | 3.45470271 |
2 | Peritonitis (HP:0002586) | 3.03446206 |
3 | Keratoconjunctivitis sicca (HP:0001097) | 3.03278359 |
4 | Chronic otitis media (HP:0000389) | 2.93485499 |
5 | Myositis (HP:0100614) | 2.87435799 |
6 | Right ventricular cardiomyopathy (HP:0011663) | 2.84760705 |
7 | Premature rupture of membranes (HP:0001788) | 2.84479495 |
8 | Orchitis (HP:0100796) | 2.68984105 |
9 | Abnormality of the nasal mucosa (HP:0000433) | 2.66703426 |
10 | Protrusio acetabuli (HP:0003179) | 2.66401196 |
11 | * Eczematoid dermatitis (HP:0000976) | 2.62769545 |
12 | Gingival bleeding (HP:0000225) | 2.62637069 |
13 | Osteolytic defects of the hand bones (HP:0009699) | 2.60196729 |
14 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.60196729 |
15 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.57300765 |
16 | Atrophic scars (HP:0001075) | 2.57261307 |
17 | Aortic aneurysm (HP:0004942) | 2.57037237 |
18 | Cerebral aneurysm (HP:0004944) | 2.55217840 |
19 | Nasal polyposis (HP:0100582) | 2.54919258 |
20 | Deep venous thrombosis (HP:0002625) | 2.53691762 |
21 | Spontaneous hematomas (HP:0007420) | 2.50172537 |
22 | * Recurrent fungal infections (HP:0002841) | 2.48773509 |
23 | Glomerulonephritis (HP:0000099) | 2.48412098 |
24 | Abnormality of the common coagulation pathway (HP:0010990) | 2.46523218 |
25 | Prolonged bleeding time (HP:0003010) | 2.45330995 |
26 | Xanthomatosis (HP:0000991) | 2.44849103 |
27 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.42459169 |
28 | Esophageal varix (HP:0002040) | 2.38038295 |
29 | Broad metatarsal (HP:0001783) | 2.37420940 |
30 | Cervical subluxation (HP:0003308) | 2.37275268 |
31 | Stomatitis (HP:0010280) | 2.34986297 |
32 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.34158659 |
33 | Recurrent cutaneous fungal infections (HP:0011370) | 2.34158659 |
34 | Arterial thrombosis (HP:0004420) | 2.29701091 |
35 | Aortic dissection (HP:0002647) | 2.28344039 |
36 | Hematochezia (HP:0002573) | 2.26460010 |
37 | Increased connective tissue (HP:0009025) | 2.25554268 |
38 | Mediastinal lymphadenopathy (HP:0100721) | 2.25458643 |
39 | Recurrent bacterial skin infections (HP:0005406) | 2.25174955 |
40 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.20972121 |
41 | Purpura (HP:0000979) | 2.20468435 |
42 | * Gingivitis (HP:0000230) | 2.19671280 |
43 | Systemic lupus erythematosus (HP:0002725) | 2.19249789 |
44 | * Interstitial pulmonary disease (HP:0006530) | 2.16662983 |
45 | Hemorrhage of the eye (HP:0011885) | 2.16652730 |
46 | Meningitis (HP:0001287) | 2.16538269 |
47 | Thick nail (HP:0001805) | 2.15726162 |
48 | Recurrent viral infections (HP:0004429) | 2.15432194 |
49 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.14640717 |
50 | Mucopolysacchariduria (HP:0008155) | 2.14566391 |
51 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.14566391 |
52 | Mitral stenosis (HP:0001718) | 2.14171438 |
53 | Hypoglycemic coma (HP:0001325) | 2.14027878 |
54 | Recurrent abscess formation (HP:0002722) | 2.13999387 |
55 | Malnutrition (HP:0004395) | 2.13662742 |
56 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.13625591 |
57 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.13625591 |
58 | Abnormality of glycolipid metabolism (HP:0010969) | 2.13625591 |
59 | Recurrent skin infections (HP:0001581) | 2.12483839 |
60 | Abnormality of macrophages (HP:0004311) | 2.12225786 |
61 | Acne (HP:0001061) | 2.11086073 |
62 | Complement deficiency (HP:0004431) | 2.10012669 |
63 | Emphysema (HP:0002097) | 2.08627160 |
64 | Gangrene (HP:0100758) | 2.07905552 |
65 | Vasculitis (HP:0002633) | 2.07201287 |
66 | Vertebral compression fractures (HP:0002953) | 2.07001950 |
67 | * Increased IgE level (HP:0003212) | 2.06391119 |
68 | Pulmonary infiltrates (HP:0002113) | 2.05098875 |
69 | Autoimmune thrombocytopenia (HP:0001973) | 2.05015709 |
70 | Vascular tortuosity (HP:0004948) | 2.04974887 |
71 | Gastrointestinal infarctions (HP:0005244) | 2.04292026 |
72 | Hyporeflexia of lower limbs (HP:0002600) | 2.03832622 |
73 | Increased variability in muscle fiber diameter (HP:0003557) | 2.03547926 |
74 | Periodontitis (HP:0000704) | 2.03378532 |
75 | Milia (HP:0001056) | 2.02477879 |
76 | Recurrent bronchitis (HP:0002837) | 2.02409079 |
77 | Loss of speech (HP:0002371) | 2.02165271 |
78 | Arterial tortuosity (HP:0005116) | 2.00544490 |
79 | Asymmetric septal hypertrophy (HP:0001670) | 2.00175209 |
80 | Polycythemia (HP:0001901) | 1.99440147 |
81 | Encephalitis (HP:0002383) | 1.98486839 |
82 | Pustule (HP:0200039) | 1.97974566 |
83 | Inflammation of the large intestine (HP:0002037) | 1.96920244 |
84 | Colitis (HP:0002583) | 1.96642612 |
85 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.95816284 |
86 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.95816284 |
87 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.95816284 |
88 | Abnormality of complement system (HP:0005339) | 1.95343068 |
89 | Vacuolated lymphocytes (HP:0001922) | 1.94917833 |
90 | Abnormality of the peritoneum (HP:0002585) | 1.93935728 |
91 | Gastrointestinal stroma tumor (HP:0100723) | 1.93494669 |
92 | Dilatation of the ascending aorta (HP:0005111) | 1.92714379 |
93 | Retrobulbar optic neuritis (HP:0100654) | 1.92673741 |
94 | Optic neuritis (HP:0100653) | 1.92673741 |
95 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.92529247 |
96 | Mitral valve prolapse (HP:0001634) | 1.91738422 |
97 | Chest pain (HP:0100749) | 1.91041937 |
98 | Abnormality of proline metabolism (HP:0010907) | 1.89786948 |
99 | Hydroxyprolinuria (HP:0003080) | 1.89786948 |
100 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.89609940 |
101 | Thin bony cortex (HP:0002753) | 1.89167292 |
102 | Abnormality of the endocardium (HP:0004306) | 1.87543792 |
103 | Hemoptysis (HP:0002105) | 1.86955325 |
104 | * Aneurysm (HP:0002617) | 1.85745259 |
105 | Gastrointestinal inflammation (HP:0004386) | 1.84307705 |
106 | Abnormality of the pericardium (HP:0001697) | 1.83734577 |
107 | Dysostosis multiplex (HP:0000943) | 1.83396816 |
108 | Pulmonary embolism (HP:0002204) | 1.83185810 |
109 | Tetraparesis (HP:0002273) | 1.81927977 |
110 | Distal lower limb muscle weakness (HP:0009053) | 1.81926693 |
111 | Obstructive lung disease (HP:0006536) | 1.81134116 |
112 | Chronic obstructive pulmonary disease (HP:0006510) | 1.81134116 |
113 | Muscle fiber splitting (HP:0003555) | 1.80585395 |
114 | Abnormality of the pleura (HP:0002103) | 1.80551143 |
115 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.80545082 |
116 | Joint swelling (HP:0001386) | 1.80034618 |
117 | Petechiae (HP:0000967) | 1.79295982 |
118 | Shallow orbits (HP:0000586) | 1.78059127 |
119 | Epistaxis (HP:0000421) | 1.77288238 |
120 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.73005610 |
121 | Ectopia lentis (HP:0001083) | 1.72575459 |
122 | Keratoconjunctivitis (HP:0001096) | 1.72419252 |
123 | Increased cerebral lipofuscin (HP:0011813) | 1.71938166 |
124 | Hypoalphalipoproteinemia (HP:0003233) | 1.71722891 |
125 | Joint hemorrhage (HP:0005261) | 1.71418427 |
126 | Menorrhagia (HP:0000132) | 1.69364321 |
127 | Abnormality of T cell number (HP:0011839) | 1.69085763 |
128 | Abnormality of T cell physiology (HP:0011840) | 1.68648473 |
129 | Ankle contracture (HP:0006466) | 1.68551132 |
130 | Fragile skin (HP:0001030) | 1.67166726 |
131 | Nephritis (HP:0000123) | 1.65951022 |
132 | Hyperglycemia (HP:0003074) | 1.64411975 |
133 | Amyloidosis (HP:0011034) | 1.64220041 |
134 | * Skin ulcer (HP:0200042) | 1.62929252 |
135 | Ventricular tachycardia (HP:0004756) | 1.62563938 |
136 | T lymphocytopenia (HP:0005403) | 1.61644146 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ERN1 | 3.73969112 |
2 | TRIB3 | 3.23562434 |
3 | JAK3 | 2.88164224 |
4 | TYK2 | 2.70661217 |
5 | PRPF4B | 2.70554938 |
6 | MAP4K1 | 2.64452643 |
7 | RIPK4 | 2.57773244 |
8 | MAP3K14 | 2.50609716 |
9 | SIK1 | 2.26466387 |
10 | TBK1 | 2.22145123 |
11 | * FGFR4 | 1.94107567 |
12 | * JAK1 | 1.87073939 |
13 | TAOK3 | 1.85556778 |
14 | PKN2 | 1.85168658 |
15 | IRAK3 | 1.81696837 |
16 | PTK6 | 1.81603652 |
17 | TTN | 1.79092305 |
18 | ZAP70 | 1.77650816 |
19 | TGFBR2 | 1.74578701 |
20 | IKBKE | 1.73163376 |
21 | TXK | 1.65927959 |
22 | RIPK1 | 1.52900942 |
23 | CHUK | 1.52663064 |
24 | STK10 | 1.51438363 |
25 | IKBKB | 1.49285129 |
26 | MAP3K3 | 1.47681474 |
27 | FLT3 | 1.46722501 |
28 | CDC42BPA | 1.46269347 |
29 | FES | 1.45865951 |
30 | INSRR | 1.45066109 |
31 | BLK | 1.42620294 |
32 | EEF2K | 1.39678078 |
33 | LRRK2 | 1.39346407 |
34 | ITK | 1.37301804 |
35 | CSK | 1.35309881 |
36 | NEK9 | 1.26334765 |
37 | KIT | 1.26205074 |
38 | MAPK15 | 1.24254572 |
39 | KSR2 | 1.23527637 |
40 | EPHA2 | 1.17199595 |
41 | SMG1 | 1.16543608 |
42 | * EPHB1 | 1.15834704 |
43 | BTK | 1.15709021 |
44 | MST1R | 1.13541537 |
45 | IRAK4 | 1.13065881 |
46 | TAOK1 | 1.12423882 |
47 | MAP3K6 | 1.12293065 |
48 | PDGFRA | 1.09860005 |
49 | TRPM7 | 1.09368286 |
50 | * JAK2 | 1.05237394 |
51 | * MAP3K1 | 1.03383033 |
52 | PIM2 | 1.03101088 |
53 | MARK2 | 1.01623469 |
54 | MAP3K2 | 1.00552823 |
55 | LATS1 | 0.96976392 |
56 | PDGFRB | 0.95909873 |
57 | SIK3 | 0.95780082 |
58 | TEC | 0.94761557 |
59 | MAPKAPK3 | 0.93591050 |
60 | BMX | 0.93530685 |
61 | PTK2 | 0.92543403 |
62 | TAOK2 | 0.91561453 |
63 | RPS6KA4 | 0.88826156 |
64 | MAP2K3 | 0.88041869 |
65 | ICK | 0.88032851 |
66 | LCK | 0.87586058 |
67 | DMPK | 0.86248530 |
68 | PDPK1 | 0.85472831 |
69 | * FGFR3 | 0.84880150 |
70 | MYLK | 0.84209300 |
71 | MST4 | 0.83528915 |
72 | MAPK7 | 0.83379394 |
73 | * HCK | 0.83053978 |
74 | MAP3K10 | 0.80760996 |
75 | SGK3 | 0.80726075 |
76 | PRKD2 | 0.80623356 |
77 | MATK | 0.78870493 |
78 | TGFBR1 | 0.76084665 |
79 | MET | 0.74952729 |
80 | MAPK11 | 0.74670878 |
81 | CSF1R | 0.74212193 |
82 | FGR | 0.74059468 |
83 | CAMK1D | 0.73776709 |
84 | GSK3A | 0.73359072 |
85 | LYN | 0.72887334 |
86 | PIK3CG | 0.72845757 |
87 | MAP3K7 | 0.71318447 |
88 | MAP3K13 | 0.71031710 |
89 | PDK1 | 0.70923304 |
90 | MAP2K2 | 0.70330468 |
91 | MAP3K11 | 0.70118594 |
92 | PIM1 | 0.69743151 |
93 | CDK6 | 0.69178068 |
94 | MAPK12 | 0.69026877 |
95 | STK3 | 0.68370482 |
96 | BMPR2 | 0.68326996 |
97 | YES1 | 0.67981321 |
98 | KDR | 0.67644074 |
99 | MARK3 | 0.67624588 |
100 | CDK12 | 0.66716821 |
101 | SYK | 0.64659163 |
102 | TIE1 | 0.63098084 |
103 | CLK1 | 0.62370859 |
104 | MAP2K6 | 0.59542340 |
105 | TNK2 | 0.56244233 |
106 | * MTOR | 0.56002685 |
107 | PRKCH | 0.55686250 |
108 | RPS6KA2 | 0.55533921 |
109 | DYRK1B | 0.54417673 |
110 | STK24 | 0.53167946 |
111 | RPS6KB2 | 0.53012603 |
112 | PRKD1 | 0.52830995 |
113 | SGK2 | 0.51050338 |
114 | PRKAA2 | 0.50696799 |
115 | IGF1R | 0.50381906 |
116 | STK38 | 0.48122508 |
117 | PAK2 | 0.48112103 |
118 | FRK | 0.47638481 |
119 | * HIPK2 | 0.47212196 |
120 | SIK2 | 0.46066577 |
121 | CDK9 | 0.45773036 |
122 | ABL1 | 0.45614758 |
123 | EGFR | 0.45607209 |
124 | GRK6 | 0.45392228 |
125 | FYN | 0.45248837 |
126 | RPS6KL1 | 0.43934157 |
127 | RPS6KC1 | 0.43934157 |
128 | PIK3CA | 0.43762012 |
129 | MAPK4 | 0.43637800 |
130 | * MAPKAPK2 | 0.43115303 |
131 | PRKG2 | 0.42164119 |
132 | PRKCQ | 0.41374648 |
133 | INSR | 0.36975906 |
134 | DDR2 | 0.36533877 |
135 | BCKDK | 0.34052819 |
136 | * RET | 0.34010503 |
137 | LMTK2 | 0.33682085 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.11476621 |
2 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.10279556 |
3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.07133011 |
4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.95031648 |
5 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.93759762 |
6 | * Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.92145080 |
7 | * Toxoplasmosis_Homo sapiens_hsa05145 | 1.71516066 |
8 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.61227701 |
9 | * Measles_Homo sapiens_hsa05162 | 1.60269697 |
10 | * Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.60159039 |
11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.56917012 |
12 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.55292771 |
13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.54193582 |
14 | Malaria_Homo sapiens_hsa05144 | 1.52959780 |
15 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.52684403 |
16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.51107157 |
17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.49522179 |
18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.32211999 |
19 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.32001938 |
20 | Pertussis_Homo sapiens_hsa05133 | 1.29096507 |
21 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.28889481 |
22 | Legionellosis_Homo sapiens_hsa05134 | 1.27539078 |
23 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.23111946 |
24 | * AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.20795371 |
25 | Influenza A_Homo sapiens_hsa05164 | 1.19272958 |
26 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.18941097 |
27 | * Insulin resistance_Homo sapiens_hsa04931 | 1.18788299 |
28 | * Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.18353754 |
29 | Amoebiasis_Homo sapiens_hsa05146 | 1.15731580 |
30 | Apoptosis_Homo sapiens_hsa04210 | 1.13886312 |
31 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.13592913 |
32 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.13537072 |
33 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.13278890 |
34 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.13013470 |
35 | * Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.09108722 |
36 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.08948735 |
37 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.07966325 |
38 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.07815026 |
39 | Focal adhesion_Homo sapiens_hsa04510 | 1.06797592 |
40 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.05694419 |
41 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.05643634 |
42 | Lysosome_Homo sapiens_hsa04142 | 1.04257730 |
43 | Tuberculosis_Homo sapiens_hsa05152 | 1.03177716 |
44 | * Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.02670073 |
45 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.00350157 |
46 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.00012028 |
47 | * Hepatitis C_Homo sapiens_hsa05160 | 1.00005074 |
48 | ABC transporters_Homo sapiens_hsa02010 | 0.99379912 |
49 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.98201458 |
50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.97644983 |
51 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.97531276 |
52 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.96108655 |
53 | Allograft rejection_Homo sapiens_hsa05330 | 0.95145271 |
54 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.92690681 |
55 | Adherens junction_Homo sapiens_hsa04520 | 0.91705482 |
56 | Phagosome_Homo sapiens_hsa04145 | 0.87678032 |
57 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.87602877 |
58 | Histidine metabolism_Homo sapiens_hsa00340 | 0.87557751 |
59 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.86823443 |
60 | Shigellosis_Homo sapiens_hsa05131 | 0.86784008 |
61 | * Pancreatic cancer_Homo sapiens_hsa05212 | 0.85808320 |
62 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.83886301 |
63 | * Hepatitis B_Homo sapiens_hsa05161 | 0.80931432 |
64 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.79203032 |
65 | * Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.78466350 |
66 | Platelet activation_Homo sapiens_hsa04611 | 0.77568121 |
67 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.76165072 |
68 | * Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.76157028 |
69 | Salmonella infection_Homo sapiens_hsa05132 | 0.75906562 |
70 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.74421768 |
71 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.73390842 |
72 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.71302343 |
73 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.70976665 |
74 | Other glycan degradation_Homo sapiens_hsa00511 | 0.70155308 |
75 | Asthma_Homo sapiens_hsa05310 | 0.69387275 |
76 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.68474742 |
77 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.68189586 |
78 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.66616909 |
79 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.65892270 |
80 | Galactose metabolism_Homo sapiens_hsa00052 | 0.65779030 |
81 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.64934269 |
82 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.64427127 |
83 | Endometrial cancer_Homo sapiens_hsa05213 | 0.64184759 |
84 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.63618908 |
85 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.62845814 |
86 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.62396692 |
87 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.61681877 |
88 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.60905984 |
89 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.60801291 |
90 | Prion diseases_Homo sapiens_hsa05020 | 0.60418229 |
91 | Bladder cancer_Homo sapiens_hsa05219 | 0.60037454 |
92 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.59307638 |
93 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.59253118 |
94 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.58003982 |
95 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.57431518 |
96 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.56090968 |
97 | Prostate cancer_Homo sapiens_hsa05215 | 0.55965038 |
98 | Endocytosis_Homo sapiens_hsa04144 | 0.55812720 |
99 | * FoxO signaling pathway_Homo sapiens_hsa04068 | 0.55295408 |
100 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.54925886 |
101 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.54741934 |
102 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.54602395 |
103 | Lysine degradation_Homo sapiens_hsa00310 | 0.53921857 |
104 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.53649699 |
105 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.52360620 |
106 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.52356528 |
107 | * HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.50971107 |
108 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.50655496 |
109 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.50649303 |
110 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.50505516 |
111 | HTLV-I infection_Homo sapiens_hsa05166 | 0.50469688 |
112 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.49909139 |
113 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.49400903 |
114 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.49381087 |
115 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.49323804 |
116 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.48181461 |
117 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.48124622 |
118 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.47382312 |
119 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.47202596 |
120 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.47077184 |
121 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.45234246 |
122 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.44647822 |
123 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.44313236 |
124 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.42726391 |