

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | epidermal cell differentiation (GO:0009913) | 8.52456941 |
| 2 | O-glycan processing (GO:0016266) | 7.78995727 |
| 3 | retina homeostasis (GO:0001895) | 7.63626272 |
| 4 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 7.36107647 |
| 5 | apical protein localization (GO:0045176) | 7.03033019 |
| 6 | long-chain fatty acid biosynthetic process (GO:0042759) | 6.71644207 |
| 7 | establishment of skin barrier (GO:0061436) | 6.32387121 |
| 8 | lipoxygenase pathway (GO:0019372) | 6.27506496 |
| 9 | positive regulation of endothelial cell differentiation (GO:0045603) | 6.06352461 |
| 10 | hair cell differentiation (GO:0035315) | 5.65085170 |
| 11 | membrane raft organization (GO:0031579) | 5.59202026 |
| 12 | linoleic acid metabolic process (GO:0043651) | 5.46803292 |
| 13 | regulation of water loss via skin (GO:0033561) | 5.42530813 |
| 14 | regulation of platelet aggregation (GO:0090330) | 5.38586898 |
| 15 | protein O-linked glycosylation (GO:0006493) | 5.19763460 |
| 16 | positive regulation of p38MAPK cascade (GO:1900745) | 5.07238991 |
| 17 | multicellular organismal water homeostasis (GO:0050891) | 5.01049641 |
| 18 | negative regulation of interleukin-17 production (GO:0032700) | 4.99700493 |
| 19 | epidermis development (GO:0008544) | 4.98721125 |
| 20 | localization within membrane (GO:0051668) | 4.96703835 |
| 21 | negative regulation of cell-cell adhesion (GO:0022408) | 4.82935481 |
| 22 | asymmetric protein localization (GO:0008105) | 4.69322723 |
| 23 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 4.66913039 |
| 24 | antimicrobial humoral response (GO:0019730) | 4.60771212 |
| 25 | regulation of endothelial cell differentiation (GO:0045601) | 4.51281940 |
| 26 | negative regulation of platelet activation (GO:0010544) | 4.50145948 |
| 27 | superoxide anion generation (GO:0042554) | 4.40792351 |
| 28 | water homeostasis (GO:0030104) | 4.34473341 |
| 29 | negative regulation of cytokine-mediated signaling pathway (GO:0001960) | 4.27388682 |
| 30 | negative regulation of response to cytokine stimulus (GO:0060761) | 4.16460968 |
| 31 | regulation of mitochondrial depolarization (GO:0051900) | 4.09730238 |
| 32 | regulation of integrin-mediated signaling pathway (GO:2001044) | 3.86507281 |
| 33 | regulation of p38MAPK cascade (GO:1900744) | 3.84413927 |
| 34 | regulation of protein polyubiquitination (GO:1902914) | 3.80611127 |
| 35 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.78673227 |
| 36 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 3.78034323 |
| 37 | regulation of cholesterol homeostasis (GO:2000188) | 3.70419412 |
| 38 | positive regulation of vasodilation (GO:0045909) | 3.68024580 |
| 39 | defense response to fungus (GO:0050832) | 3.60625495 |
| 40 | * negative regulation of bone mineralization (GO:0030502) | 3.56842200 |
| 41 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 3.49284726 |
| 42 | negative regulation of muscle cell apoptotic process (GO:0010656) | 3.44239545 |
| 43 | transepithelial transport (GO:0070633) | 3.42336259 |
| 44 | glomerular filtration (GO:0003094) | 3.31313948 |
| 45 | intestinal epithelial cell development (GO:0060576) | 3.27953841 |
| 46 | regulation of toll-like receptor 4 signaling pathway (GO:0034143) | 3.22937103 |
| 47 | regulation of interleukin-17 production (GO:0032660) | 3.14992591 |
| 48 | * negative regulation of biomineral tissue development (GO:0070168) | 3.14510599 |
| 49 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.13739671 |
| 50 | embryonic process involved in female pregnancy (GO:0060136) | 3.11933394 |
| 51 | desmosome organization (GO:0002934) | 3.11457035 |
| 52 | regulation of homotypic cell-cell adhesion (GO:0034110) | 3.10919033 |
| 53 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 3.09110035 |
| 54 | regulation of bile acid biosynthetic process (GO:0070857) | 3.07229026 |
| 55 | negative regulation of cell-substrate adhesion (GO:0010812) | 3.04089031 |
| 56 | wound healing (GO:0042060) | 3.01298292 |
| 57 | renal filtration (GO:0097205) | 2.98966256 |
| 58 | one-carbon compound transport (GO:0019755) | 2.96123561 |
| 59 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.94800249 |
| 60 | endothelial cell chemotaxis (GO:0035767) | 2.92452642 |
| 61 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.92102691 |
| 62 | regulation of chemokine biosynthetic process (GO:0045073) | 2.88727341 |
| 63 | eyelid development in camera-type eye (GO:0061029) | 2.87216182 |
| 64 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.84974002 |
| 65 | negative regulation of interferon-gamma production (GO:0032689) | 2.83668706 |
| 66 | regulation of type 2 immune response (GO:0002828) | 2.81265487 |
| 67 | ectoderm development (GO:0007398) | 2.80722102 |
| 68 | positive regulation of chemokine secretion (GO:0090197) | 2.77894797 |
| 69 | regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664) | 2.75553417 |
| 70 | response to vitamin A (GO:0033189) | 2.73492543 |
| 71 | epithelial cell differentiation (GO:0030855) | 2.73296757 |
| 72 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.68288417 |
| 73 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.66643325 |
| 74 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.66643325 |
| 75 | Rho protein signal transduction (GO:0007266) | 2.63779253 |
| 76 | metanephric mesenchyme development (GO:0072075) | 2.63264242 |
| 77 | regulation of T cell migration (GO:2000404) | 2.59735819 |
| 78 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.57748588 |
| 79 | enteric nervous system development (GO:0048484) | 2.56976408 |
| 80 | negative regulation of vascular permeability (GO:0043116) | 2.56341775 |
| 81 | interkinetic nuclear migration (GO:0022027) | 2.52862789 |
| 82 | regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) | 2.52218443 |
| 83 | epithelium development (GO:0060429) | 2.51893331 |
| 84 | antibacterial humoral response (GO:0019731) | 2.48866590 |
| 85 | lymph node development (GO:0048535) | 2.47224587 |
| 86 | hypotonic response (GO:0006971) | 2.45613241 |
| 87 | negative regulation of smooth muscle cell proliferation (GO:0048662) | 2.44600457 |
| 88 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.43971640 |
| 89 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.43971640 |
| 90 | regulation of platelet activation (GO:0010543) | 2.43683430 |
| 91 | defense response to Gram-negative bacterium (GO:0050829) | 2.42467490 |
| 92 | tissue homeostasis (GO:0001894) | 2.41901360 |
| 93 | response to leptin (GO:0044321) | 2.41150187 |
| 94 | fibroblast migration (GO:0010761) | 2.41098072 |
| 95 | regulation of vasodilation (GO:0042312) | 2.40140463 |
| 96 | response to fungus (GO:0009620) | 2.39535825 |
| 97 | hippo signaling (GO:0035329) | 2.31987934 |
| 98 | keratinization (GO:0031424) | 17.0180049 |
| 99 | peptide cross-linking (GO:0018149) | 12.1384178 |
| 100 | keratinocyte differentiation (GO:0030216) | 10.0306992 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.63207631 |
| 2 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.35057692 |
| 3 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.14557226 |
| 4 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.93809751 |
| 5 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.75043006 |
| 6 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.55154133 |
| 7 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.33015892 |
| 8 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 2.15541872 |
| 9 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.07200312 |
| 10 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.07070034 |
| 11 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.01775576 |
| 12 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 2.01508005 |
| 13 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.92760207 |
| 14 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.91907846 |
| 15 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.90214845 |
| 16 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.86245455 |
| 17 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.85976365 |
| 18 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.82490656 |
| 19 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.82284970 |
| 20 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.80566238 |
| 21 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.78324378 |
| 22 | CJUN_26792858_Chip-Seq_BT549_Human | 1.74365936 |
| 23 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.66037746 |
| 24 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.65283646 |
| 25 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.63766565 |
| 26 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.63119893 |
| 27 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.60900301 |
| 28 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.60441863 |
| 29 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.60212734 |
| 30 | VDR_22108803_ChIP-Seq_LS180_Human | 1.57305133 |
| 31 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.55046432 |
| 32 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.55046432 |
| 33 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.55037463 |
| 34 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.53787602 |
| 35 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.53677245 |
| 36 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.47790760 |
| 37 | RXR_22108803_ChIP-Seq_LS180_Human | 1.47711895 |
| 38 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.46014613 |
| 39 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.43511914 |
| 40 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.43084871 |
| 41 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.40885552 |
| 42 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.40849344 |
| 43 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.39411308 |
| 44 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.39324128 |
| 45 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.38295069 |
| 46 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.36995915 |
| 47 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.36985117 |
| 48 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.36257267 |
| 49 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.34002668 |
| 50 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.30798056 |
| 51 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.30212014 |
| 52 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.29503726 |
| 53 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.27562809 |
| 54 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.27478392 |
| 55 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.27374966 |
| 56 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.24692963 |
| 57 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.23753781 |
| 58 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.22677663 |
| 59 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.22677663 |
| 60 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.21209720 |
| 61 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.20015800 |
| 62 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.18462958 |
| 63 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.15537519 |
| 64 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.15283613 |
| 65 | * JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.13168480 |
| 66 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12476295 |
| 67 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.12386376 |
| 68 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.11428407 |
| 69 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.10236202 |
| 70 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.10236202 |
| 71 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.06795907 |
| 72 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.04120387 |
| 73 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.03763667 |
| 74 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.03722501 |
| 75 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03666349 |
| 76 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02574710 |
| 77 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.01211635 |
| 78 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.00428768 |
| 79 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.98708459 |
| 80 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.96577339 |
| 81 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94553109 |
| 82 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.91681163 |
| 83 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.91165951 |
| 84 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.90877068 |
| 85 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.90662616 |
| 86 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.88703461 |
| 87 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.88145498 |
| 88 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88112618 |
| 89 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.87708105 |
| 90 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.85748534 |
| 91 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.85748534 |
| 92 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.85748534 |
| 93 | MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse | 0.85571015 |
| 94 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.85472807 |
| 95 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.85249736 |
| 96 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.85176188 |
| 97 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.84830888 |
| 98 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.84612566 |
| 99 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.84134601 |
| 100 | AR_25329375_ChIP-Seq_VCAP_Human | 0.83166537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005275_abnormal_skin_tensile | 6.63225009 |
| 2 | MP0002796_impaired_skin_barrier | 4.66711140 |
| 3 | MP0004043_abnormal_pH_regulation | 3.93884234 |
| 4 | MP0010352_gastrointestinal_tract_polyps | 3.62418740 |
| 5 | MP0005503_abnormal_tendon_morphology | 3.17712960 |
| 6 | MP0005501_abnormal_skin_physiology | 3.13686341 |
| 7 | MP0005670_abnormal_white_adipose | 2.99462352 |
| 8 | MP0010678_abnormal_skin_adnexa | 2.98307070 |
| 9 | MP0003724_increased_susceptibility_to | 2.28304341 |
| 10 | MP0009780_abnormal_chondrocyte_physiolo | 2.18288285 |
| 11 | MP0010368_abnormal_lymphatic_system | 2.17421025 |
| 12 | MP0004185_abnormal_adipocyte_glucose | 2.12373993 |
| 13 | MP0005666_abnormal_adipose_tissue | 2.10076149 |
| 14 | MP0010234_abnormal_vibrissa_follicle | 11.7816955 |
| 15 | MP0000465_gastrointestinal_hemorrhage | 1.82728597 |
| 16 | MP0001851_eye_inflammation | 1.73460897 |
| 17 | MP0003705_abnormal_hypodermis_morpholog | 1.69630226 |
| 18 | MP0000467_abnormal_esophagus_morphology | 1.62806094 |
| 19 | MP0000678_abnormal_parathyroid_gland | 1.61604307 |
| 20 | MP0002098_abnormal_vibrissa_morphology | 1.57329720 |
| 21 | MP0005375_adipose_tissue_phenotype | 1.51528938 |
| 22 | MP0003453_abnormal_keratinocyte_physiol | 1.51359507 |
| 23 | MP0010771_integument_phenotype | 1.45357571 |
| 24 | MP0002166_altered_tumor_susceptibility | 1.43336453 |
| 25 | MP0005409_darkened_coat_color | 1.41222103 |
| 26 | MP0002249_abnormal_larynx_morphology | 1.39282563 |
| 27 | MP0003828_pulmonary_edema | 1.35772646 |
| 28 | MP0001216_abnormal_epidermal_layer | 1.28757181 |
| 29 | MP0002108_abnormal_muscle_morphology | 1.28355311 |
| 30 | MP0001879_abnormal_lymphatic_vessel | 1.21605415 |
| 31 | MP0009333_abnormal_splenocyte_physiolog | 1.20856644 |
| 32 | MP0004130_abnormal_muscle_cell | 1.20442730 |
| 33 | MP0005023_abnormal_wound_healing | 1.12989983 |
| 34 | MP0009115_abnormal_fat_cell | 1.11683688 |
| 35 | MP0000762_abnormal_tongue_morphology | 1.10046833 |
| 36 | MP0001502_abnormal_circadian_rhythm | 1.08049021 |
| 37 | MP0002060_abnormal_skin_morphology | 1.05806738 |
| 38 | MP0002933_joint_inflammation | 1.04075620 |
| 39 | MP0000681_abnormal_thyroid_gland | 1.00546452 |
| 40 | MP0006138_congestive_heart_failure | 0.97095779 |
| 41 | MP0000377_abnormal_hair_follicle | 0.95782963 |
| 42 | MP0004947_skin_inflammation | 0.95287588 |
| 43 | MP0002009_preneoplasia | 0.93013098 |
| 44 | MP0004264_abnormal_extraembryonic_tissu | 0.92259364 |
| 45 | MP0000613_abnormal_salivary_gland | 0.88594755 |
| 46 | MP0005166_decreased_susceptibility_to | 0.88310108 |
| 47 | MP0008004_abnormal_stomach_pH | 0.87130184 |
| 48 | MP0001853_heart_inflammation | 0.86126109 |
| 49 | MP0001784_abnormal_fluid_regulation | 0.86036570 |
| 50 | MP0002006_tumorigenesis | 0.81614604 |
| 51 | MP0000470_abnormal_stomach_morphology | 0.74955176 |
| 52 | MP0000003_abnormal_adipose_tissue | 0.74944177 |
| 53 | MP0000049_abnormal_middle_ear | 0.72862716 |
| 54 | MP0001765_abnormal_ion_homeostasis | 0.70989435 |
| 55 | MP0001533_abnormal_skeleton_physiology | 0.69179449 |
| 56 | MP0005365_abnormal_bile_salt | 0.68159632 |
| 57 | MP0002971_abnormal_brown_adipose | 0.66583026 |
| 58 | MP0003566_abnormal_cell_adhesion | 0.66308868 |
| 59 | MP0001756_abnormal_urination | 0.66021079 |
| 60 | MP0000733_abnormal_muscle_development | 0.64265576 |
| 61 | MP0000920_abnormal_myelination | 0.63743853 |
| 62 | MP0005164_abnormal_response_to | 0.63341487 |
| 63 | MP0010030_abnormal_orbit_morphology | 0.62878197 |
| 64 | MP0001958_emphysema | 0.60703481 |
| 65 | MP0003938_abnormal_ear_development | 0.57342060 |
| 66 | MP0004883_abnormal_blood_vessel | 0.57115001 |
| 67 | MP0009931_abnormal_skin_appearance | 0.55778176 |
| 68 | MP0005390_skeleton_phenotype | 0.55702190 |
| 69 | MP0004885_abnormal_endolymph | 0.54894201 |
| 70 | MP0001270_distended_abdomen | 0.54565557 |
| 71 | MP0000566_synostosis | 0.52741014 |
| 72 | MP0002128_abnormal_blood_circulation | 0.51032082 |
| 73 | MP0001243_abnormal_dermal_layer | 0.48278206 |
| 74 | MP0003303_peritoneal_inflammation | 0.46742225 |
| 75 | MP0005508_abnormal_skeleton_morphology | 0.45975375 |
| 76 | MP0000759_abnormal_skeletal_muscle | 0.45683487 |
| 77 | MP0002970_abnormal_white_adipose | 0.45475321 |
| 78 | MP0001544_abnormal_cardiovascular_syste | 0.44613509 |
| 79 | MP0005385_cardiovascular_system_phenoty | 0.44613509 |
| 80 | MP0001873_stomach_inflammation | 0.44568844 |
| 81 | MP0008961_abnormal_basal_metabolism | 0.44016959 |
| 82 | MP0000371_diluted_coat_color | 0.43978568 |
| 83 | MP0005448_abnormal_energy_balance | 0.42582646 |
| 84 | MP0005647_abnormal_sex_gland | 0.42482957 |
| 85 | MP0009643_abnormal_urine_homeostasis | 0.41882137 |
| 86 | MP0003950_abnormal_plasma_membrane | 0.41076821 |
| 87 | MP0002136_abnormal_kidney_physiology | 0.41073183 |
| 88 | MP0005076_abnormal_cell_differentiation | 0.40192875 |
| 89 | MP0004087_abnormal_muscle_fiber | 0.39155984 |
| 90 | MP0010630_abnormal_cardiac_muscle | 0.38680573 |
| 91 | MP0000367_abnormal_coat/_hair | 0.38522552 |
| 92 | MP0005310_abnormal_salivary_gland | 0.38325763 |
| 93 | MP0005636_abnormal_mineral_homeostasis | 0.37684147 |
| 94 | MP0002332_abnormal_exercise_endurance | 0.37488660 |
| 95 | MP0010386_abnormal_urinary_bladder | 0.37048383 |
| 96 | MP0005646_abnormal_pituitary_gland | 0.36972009 |
| 97 | MP0002138_abnormal_hepatobiliary_system | 0.36849561 |
| 98 | MP0001542_abnormal_bone_strength | 0.35689053 |
| 99 | MP0002405_respiratory_system_inflammati | 0.35637970 |
| 100 | MP0005464_abnormal_platelet_physiology | 0.34912395 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pustule (HP:0200039) | 9.88290738 |
| 2 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 7.31995324 |
| 3 | Hyperactive renin-angiotensin system (HP:0000841) | 6.30812929 |
| 4 | Villous atrophy (HP:0011473) | 6.09467728 |
| 5 | Abnormality of small intestinal villus morphology (HP:0011472) | 6.09467728 |
| 6 | Lip pit (HP:0100267) | 5.65010979 |
| 7 | Hyperkalemia (HP:0002153) | 5.36806646 |
| 8 | Parakeratosis (HP:0001036) | 5.18063264 |
| 9 | Congenital ichthyosiform erythroderma (HP:0007431) | 5.06670216 |
| 10 | Oral leukoplakia (HP:0002745) | 5.02154451 |
| 11 | Erythroderma (HP:0001019) | 4.95105406 |
| 12 | Nasal polyposis (HP:0100582) | 4.87937587 |
| 13 | Sparse scalp hair (HP:0002209) | 4.48033387 |
| 14 | Decreased circulating renin level (HP:0003351) | 4.44192694 |
| 15 | Abnormality of the nasal mucosa (HP:0000433) | 4.37781963 |
| 16 | Acanthosis nigricans (HP:0000956) | 4.26215877 |
| 17 | Chronic bronchitis (HP:0004469) | 4.16291554 |
| 18 | Neonatal hypoglycemia (HP:0001998) | 4.01318325 |
| 19 | Brittle hair (HP:0002299) | 3.89940602 |
| 20 | Eczematoid dermatitis (HP:0000976) | 3.82567021 |
| 21 | Hypokalemic alkalosis (HP:0001949) | 3.44669068 |
| 22 | Oligodontia (HP:0000677) | 3.32649484 |
| 23 | Emphysema (HP:0002097) | 3.28244077 |
| 24 | Cystic hygroma (HP:0000476) | 3.21720110 |
| 25 | Hyperaldosteronism (HP:0000859) | 3.19095736 |
| 26 | Abnormality of chloride homeostasis (HP:0011422) | 3.18897239 |
| 27 | Abnormality of renin-angiotensin system (HP:0000847) | 3.13535478 |
| 28 | Ulnar claw (HP:0001178) | 3.09982644 |
| 29 | Dehydration (HP:0001944) | 3.03962153 |
| 30 | Renal salt wasting (HP:0000127) | 2.97500117 |
| 31 | Distal lower limb muscle weakness (HP:0009053) | 2.85428921 |
| 32 | Obstructive sleep apnea (HP:0002870) | 2.80152190 |
| 33 | Right ventricular cardiomyopathy (HP:0011663) | 2.74924869 |
| 34 | Abnormality of the salivary glands (HP:0010286) | 2.67141753 |
| 35 | Erythema (HP:0010783) | 2.65936064 |
| 36 | Hypergammaglobulinemia (HP:0010702) | 2.56789552 |
| 37 | Hoarse voice (HP:0001609) | 2.47147375 |
| 38 | Complement deficiency (HP:0004431) | 2.46420261 |
| 39 | Urticaria (HP:0001025) | 2.36608168 |
| 40 | Papillary thyroid carcinoma (HP:0002895) | 2.32583916 |
| 41 | Acne (HP:0001061) | 2.22843426 |
| 42 | Delusions (HP:0000746) | 2.20787815 |
| 43 | Verrucae (HP:0200043) | 2.20019765 |
| 44 | Papilloma (HP:0012740) | 2.20019765 |
| 45 | Adrenal overactivity (HP:0002717) | 2.19733825 |
| 46 | Aortic aneurysm (HP:0004942) | 2.15502930 |
| 47 | Abnormality of potassium homeostasis (HP:0011042) | 2.13701057 |
| 48 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.13058513 |
| 49 | Hyporeflexia of lower limbs (HP:0002600) | 2.09293184 |
| 50 | Hyponatremia (HP:0002902) | 2.08752495 |
| 51 | Absence seizures (HP:0002121) | 2.07045104 |
| 52 | Abnormality of complement system (HP:0005339) | 2.02099915 |
| 53 | Muscle fiber splitting (HP:0003555) | 2.01056069 |
| 54 | Increased IgE level (HP:0003212) | 10.3086887 |
| 55 | Nail dystrophy (HP:0008404) | 1.98579000 |
| 56 | Furrowed tongue (HP:0000221) | 1.94474217 |
| 57 | Low posterior hairline (HP:0002162) | 1.93678418 |
| 58 | Bronchitis (HP:0012387) | 1.86979315 |
| 59 | Choroideremia (HP:0001139) | 1.86550788 |
| 60 | Skin pits (HP:0100276) | 1.84581422 |
| 61 | Thoracolumbar scoliosis (HP:0002944) | 1.82964289 |
| 62 | Thickened nuchal skin fold (HP:0000474) | 1.80523799 |
| 63 | Autoamputation (HP:0001218) | 1.75078211 |
| 64 | Seborrheic dermatitis (HP:0001051) | 1.74937921 |
| 65 | Abnormality of sodium homeostasis (HP:0010931) | 1.74823657 |
| 66 | Overgrowth (HP:0001548) | 1.72708690 |
| 67 | Coarse hair (HP:0002208) | 1.72168517 |
| 68 | Aplasia/Hypoplasia of the abdominal wall musculature (HP:0010318) | 1.71421854 |
| 69 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.70778794 |
| 70 | Stenosis of the external auditory canal (HP:0000402) | 1.68545642 |
| 71 | Type 1 muscle fiber predominance (HP:0003803) | 1.67104003 |
| 72 | Muscle fiber inclusion bodies (HP:0100299) | 1.67097745 |
| 73 | Abnormality of nail color (HP:0100643) | 1.66993666 |
| 74 | Systemic lupus erythematosus (HP:0002725) | 1.66179015 |
| 75 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 1.66077196 |
| 76 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.64670585 |
| 77 | Malnutrition (HP:0004395) | 1.63525078 |
| 78 | Fine hair (HP:0002213) | 1.59825906 |
| 79 | Protrusio acetabuli (HP:0003179) | 1.57991718 |
| 80 | Glomerulonephritis (HP:0000099) | 1.57157287 |
| 81 | Advanced eruption of teeth (HP:0006288) | 1.56946624 |
| 82 | Nemaline bodies (HP:0003798) | 1.55923142 |
| 83 | Skin rash (HP:0000988) | 1.54604187 |
| 84 | Vascular tortuosity (HP:0004948) | 1.54232376 |
| 85 | Hypoplastic nipples (HP:0002557) | 1.53946246 |
| 86 | Oligodactyly (hands) (HP:0001180) | 1.52820797 |
| 87 | Laryngomalacia (HP:0001601) | 1.51278205 |
| 88 | Hypoplasia of the iris (HP:0007676) | 1.50989654 |
| 89 | Abnormality of the fingertips (HP:0001211) | 1.50638550 |
| 90 | Nephritis (HP:0000123) | 1.49739032 |
| 91 | Ectropion (HP:0000656) | 1.49160928 |
| 92 | Foot dorsiflexor weakness (HP:0009027) | 1.48035474 |
| 93 | Hypokalemia (HP:0002900) | 1.47819646 |
| 94 | Sleep apnea (HP:0010535) | 1.46879133 |
| 95 | Lymphedema (HP:0001004) | 1.46804013 |
| 96 | Asthma (HP:0002099) | 1.45271611 |
| 97 | Melanocytic nevus (HP:0000995) | 1.44980598 |
| 98 | Labial hypoplasia (HP:0000066) | 1.44162693 |
| 99 | Alkalosis (HP:0001948) | 1.43059470 |
| 100 | Difficulty running (HP:0009046) | 1.42535842 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K9 | 5.34925043 |
| 2 | RIPK1 | 3.35224535 |
| 3 | WNK1 | 3.25256135 |
| 4 | CAMK1D | 2.87351006 |
| 5 | NME1 | 2.81560941 |
| 6 | STK39 | 2.70508098 |
| 7 | TYRO3 | 2.51292670 |
| 8 | SGK2 | 2.39974150 |
| 9 | MAP3K2 | 2.34503581 |
| 10 | SGK3 | 2.29723624 |
| 11 | CAMK1G | 2.23827604 |
| 12 | LRRK2 | 2.07086715 |
| 13 | ERN1 | 2.03373388 |
| 14 | TRPM7 | 2.03042316 |
| 15 | PIK3CA | 2.01270245 |
| 16 | MAPKAPK3 | 1.95269538 |
| 17 | EPHA2 | 1.95262489 |
| 18 | MARK2 | 1.90948034 |
| 19 | WNK4 | 1.82987894 |
| 20 | SGK223 | 1.76267492 |
| 21 | SGK494 | 1.76267492 |
| 22 | OBSCN | 1.72576507 |
| 23 | STK24 | 1.62052321 |
| 24 | DMPK | 1.51931597 |
| 25 | PDGFRB | 1.49500185 |
| 26 | CSK | 1.47597866 |
| 27 | ERBB3 | 1.42199482 |
| 28 | MST4 | 1.30001319 |
| 29 | LATS1 | 1.26270348 |
| 30 | AKT3 | 1.25715682 |
| 31 | MAP3K3 | 1.24628243 |
| 32 | HIPK2 | 1.15537614 |
| 33 | MAPK15 | 1.14583200 |
| 34 | MAP3K7 | 1.14174864 |
| 35 | PRKAA2 | 1.03284267 |
| 36 | DDR2 | 1.02603798 |
| 37 | MAPK7 | 0.99856150 |
| 38 | CDK12 | 0.98155551 |
| 39 | FER | 0.97670329 |
| 40 | ICK | 0.97368075 |
| 41 | TRIB3 | 0.94507032 |
| 42 | TAOK1 | 0.94383092 |
| 43 | RPS6KA2 | 0.93243156 |
| 44 | BCR | 0.91867734 |
| 45 | IRAK1 | 0.89351897 |
| 46 | MAP3K1 | 0.84609218 |
| 47 | STK3 | 0.83740357 |
| 48 | KSR2 | 0.81834533 |
| 49 | STK38 | 0.81565606 |
| 50 | EPHB1 | 0.80855609 |
| 51 | AKT2 | 0.79697583 |
| 52 | MTOR | 0.79364725 |
| 53 | FGFR1 | 0.76686524 |
| 54 | PTK2 | 0.75832138 |
| 55 | IKBKE | 0.74695233 |
| 56 | DAPK2 | 0.74173285 |
| 57 | MET | 0.72635295 |
| 58 | EEF2K | 0.71866039 |
| 59 | CHUK | 0.68971817 |
| 60 | SIK1 | 0.67076235 |
| 61 | EPHA3 | 0.65215236 |
| 62 | NLK | 0.63468931 |
| 63 | TGFBR2 | 0.62208622 |
| 64 | CDK9 | 0.61665064 |
| 65 | MAPK1 | 0.61186586 |
| 66 | PDGFRA | 0.60937640 |
| 67 | SGK1 | 0.59738258 |
| 68 | MAPK3 | 0.58787998 |
| 69 | TBK1 | 0.57668117 |
| 70 | RPS6KA1 | 0.57496011 |
| 71 | ZAP70 | 0.57301367 |
| 72 | CDC42BPA | 0.56773206 |
| 73 | EPHB2 | 0.54557854 |
| 74 | RPS6KB1 | 0.52228702 |
| 75 | MAP3K6 | 0.52147990 |
| 76 | MAPKAPK2 | 0.51627220 |
| 77 | RET | 0.51596537 |
| 78 | MAP4K2 | 0.50506814 |
| 79 | MAP2K1 | 0.49903474 |
| 80 | CAMK4 | 0.48234774 |
| 81 | RPS6KB2 | 0.48118189 |
| 82 | PRKD2 | 0.47372936 |
| 83 | SIK3 | 0.46542877 |
| 84 | MAP2K2 | 0.43288501 |
| 85 | CAMK1 | 0.42051550 |
| 86 | OXSR1 | 0.40058180 |
| 87 | FGFR3 | 0.37915602 |
| 88 | MAPKAPK5 | 0.37209808 |
| 89 | IRAK2 | 0.36750455 |
| 90 | IRAK4 | 0.35152987 |
| 91 | TIE1 | 0.35122620 |
| 92 | AKT1 | 0.33442080 |
| 93 | PRKD1 | 0.33349996 |
| 94 | PRKAA1 | 0.32295471 |
| 95 | RPS6KA3 | 0.32263199 |
| 96 | RPS6KL1 | 0.30801258 |
| 97 | RPS6KC1 | 0.30801258 |
| 98 | MAPK4 | 0.30297567 |
| 99 | PAK2 | 0.29102017 |
| 100 | CDK3 | 0.26384034 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | * Salivary secretion_Homo sapiens_hsa04970 | 3.99951469 |
| 2 | Circadian rhythm_Homo sapiens_hsa04710 | 3.33528520 |
| 3 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 3.07951763 |
| 4 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.25358234 |
| 5 | Adherens junction_Homo sapiens_hsa04520 | 2.15038593 |
| 6 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.98911201 |
| 7 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.93438848 |
| 8 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.63330341 |
| 9 | Amoebiasis_Homo sapiens_hsa05146 | 1.56920436 |
| 10 | Malaria_Homo sapiens_hsa05144 | 1.56145388 |
| 11 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.53962848 |
| 12 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.47070410 |
| 13 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.43033335 |
| 14 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.33236832 |
| 15 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.30507059 |
| 16 | Tight junction_Homo sapiens_hsa04530 | 1.29195578 |
| 17 | Pertussis_Homo sapiens_hsa05133 | 1.27015417 |
| 18 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.22750531 |
| 19 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.19424273 |
| 20 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.19038811 |
| 21 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.14623217 |
| 22 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.14348765 |
| 23 | Prostate cancer_Homo sapiens_hsa05215 | 1.09864362 |
| 24 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.06175028 |
| 25 | Thyroid cancer_Homo sapiens_hsa05216 | 1.05033397 |
| 26 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.03176657 |
| 27 | Insulin resistance_Homo sapiens_hsa04931 | 1.02588400 |
| 28 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.02204901 |
| 29 | Influenza A_Homo sapiens_hsa05164 | 0.95352050 |
| 30 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.94565349 |
| 31 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.94439960 |
| 32 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.94049187 |
| 33 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.93899220 |
| 34 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.93750092 |
| 35 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.92120661 |
| 36 | Endocytosis_Homo sapiens_hsa04144 | 0.91281799 |
| 37 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.91188677 |
| 38 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.91074269 |
| 39 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.90850033 |
| 40 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.89533344 |
| 41 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.88679210 |
| 42 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.88123187 |
| 43 | Hepatitis C_Homo sapiens_hsa05160 | 0.87199547 |
| 44 | Focal adhesion_Homo sapiens_hsa04510 | 0.85210355 |
| 45 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.84484739 |
| 46 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.83212379 |
| 47 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.82147965 |
| 48 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.81727300 |
| 49 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.81623287 |
| 50 | Renin secretion_Homo sapiens_hsa04924 | 0.80747055 |
| 51 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.80089236 |
| 52 | Endometrial cancer_Homo sapiens_hsa05213 | 0.79902323 |
| 53 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.79804716 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.79357465 |
| 55 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.78608685 |
| 56 | Salmonella infection_Homo sapiens_hsa05132 | 0.77884134 |
| 57 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.75896171 |
| 58 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.74705054 |
| 59 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.74036904 |
| 60 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.73600147 |
| 61 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.71328550 |
| 62 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.71262221 |
| 63 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.70618165 |
| 64 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.70528137 |
| 65 | Long-term potentiation_Homo sapiens_hsa04720 | 0.70316812 |
| 66 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.69598129 |
| 67 | Tuberculosis_Homo sapiens_hsa05152 | 0.69292445 |
| 68 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.68926024 |
| 69 | Hepatitis B_Homo sapiens_hsa05161 | 0.67753154 |
| 70 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.67563352 |
| 71 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.67087185 |
| 72 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.66365408 |
| 73 | Axon guidance_Homo sapiens_hsa04360 | 0.66325346 |
| 74 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.65906489 |
| 75 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.65487153 |
| 76 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.64664293 |
| 77 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.63809480 |
| 78 | Lysine degradation_Homo sapiens_hsa00310 | 0.63808445 |
| 79 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.62375110 |
| 80 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.60958097 |
| 81 | Platelet activation_Homo sapiens_hsa04611 | 0.60436147 |
| 82 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.60086676 |
| 83 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.59809480 |
| 84 | Pathways in cancer_Homo sapiens_hsa05200 | 0.59328000 |
| 85 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.59212321 |
| 86 | Leishmaniasis_Homo sapiens_hsa05140 | 0.56884718 |
| 87 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.56423522 |
| 88 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.55759707 |
| 89 | Histidine metabolism_Homo sapiens_hsa00340 | 0.55239961 |
| 90 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.55068211 |
| 91 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55007205 |
| 92 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.54970726 |
| 93 | Gap junction_Homo sapiens_hsa04540 | 0.53319440 |
| 94 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.52084010 |
| 95 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.51012398 |
| 96 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.50629584 |
| 97 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.50426588 |
| 98 | Colorectal cancer_Homo sapiens_hsa05210 | 0.50319594 |
| 99 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.48623220 |
| 100 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.47891969 |

