STBD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.27401318
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.27401318
3L-phenylalanine metabolic process (GO:0006558)7.01114478
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.01114478
5actin-myosin filament sliding (GO:0033275)6.85398674
6muscle filament sliding (GO:0030049)6.85398674
7aromatic amino acid family catabolic process (GO:0009074)6.46170418
8triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.01153541
9negative regulation of fibrinolysis (GO:0051918)5.76455012
10indole-containing compound catabolic process (GO:0042436)5.75037515
11indolalkylamine catabolic process (GO:0046218)5.75037515
12tryptophan catabolic process (GO:0006569)5.75037515
13actin-mediated cell contraction (GO:0070252)5.73872286
14kynurenine metabolic process (GO:0070189)5.73213294
15bile acid biosynthetic process (GO:0006699)5.69111848
16glyoxylate metabolic process (GO:0046487)5.64785306
17NADH metabolic process (GO:0006734)5.62775085
18sarcoplasmic reticulum calcium ion transport (GO:0070296)5.60834241
19skeletal muscle contraction (GO:0003009)5.52647162
20urea metabolic process (GO:0019627)5.47193477
21urea cycle (GO:0000050)5.47193477
22tryptophan metabolic process (GO:0006568)5.46772854
23regulation of fibrinolysis (GO:0051917)5.42053587
24peptidyl-glutamic acid carboxylation (GO:0017187)5.31803136
25protein carboxylation (GO:0018214)5.31803136
26high-density lipoprotein particle remodeling (GO:0034375)5.30350311
27alpha-linolenic acid metabolic process (GO:0036109)5.29456380
28creatine metabolic process (GO:0006600)5.28708522
29cysteine metabolic process (GO:0006534)5.28197521
30regulation of protein activation cascade (GO:2000257)5.28134734
31regulation of skeletal muscle contraction (GO:0014819)5.23428664
32sulfur amino acid catabolic process (GO:0000098)5.21550157
33complement activation, alternative pathway (GO:0006957)5.20186200
34nitrogen cycle metabolic process (GO:0071941)5.02664908
35regulation of complement activation (GO:0030449)4.96995700
36bile acid metabolic process (GO:0008206)4.81804785
37lysine catabolic process (GO:0006554)4.76299973
38lysine metabolic process (GO:0006553)4.76299973
39serine family amino acid catabolic process (GO:0009071)4.74834660
40fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.74600958
41aromatic amino acid family metabolic process (GO:0009072)4.68608401
42regulation of triglyceride catabolic process (GO:0010896)4.65430109
43reverse cholesterol transport (GO:0043691)4.64642309
44tyrosine metabolic process (GO:0006570)4.59387131
45homocysteine metabolic process (GO:0050667)4.59309469
46amino-acid betaine metabolic process (GO:0006577)4.51378095
47regulation of cholesterol esterification (GO:0010872)4.51128887
48protein-lipid complex remodeling (GO:0034368)4.49118484
49macromolecular complex remodeling (GO:0034367)4.49118484
50plasma lipoprotein particle remodeling (GO:0034369)4.49118484
51acylglycerol homeostasis (GO:0055090)4.47661250
52triglyceride homeostasis (GO:0070328)4.47661250
53alpha-amino acid catabolic process (GO:1901606)4.39736606
54fatty acid homeostasis (GO:0055089)4.39437961
55cellular ketone body metabolic process (GO:0046950)4.36695832
56actin filament-based movement (GO:0030048)4.32925675
57coenzyme catabolic process (GO:0009109)4.29474089
58glycogen catabolic process (GO:0005980)4.29177156
59regulation of sequestering of triglyceride (GO:0010889)4.27998034
60negative regulation of sterol transport (GO:0032372)4.26912455
61negative regulation of cholesterol transport (GO:0032375)4.26912455
62phospholipid efflux (GO:0033700)4.25702095
63plasma lipoprotein particle clearance (GO:0034381)4.22826004
64oxaloacetate metabolic process (GO:0006107)4.22778312
65positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.21372871
66bile acid and bile salt transport (GO:0015721)4.20219571
67fructose metabolic process (GO:0006000)4.19100951
68fibrinolysis (GO:0042730)4.16532434
69cellular glucuronidation (GO:0052695)4.14558578
70glucan catabolic process (GO:0009251)4.12793359
71glycine metabolic process (GO:0006544)4.09270492
72indolalkylamine metabolic process (GO:0006586)4.06852479
73cellular amino acid catabolic process (GO:0009063)4.05838051
74cholesterol efflux (GO:0033344)4.03723124
75carnitine shuttle (GO:0006853)4.03643390
76benzene-containing compound metabolic process (GO:0042537)3.97695388
77drug catabolic process (GO:0042737)3.95739334
78striated muscle contraction (GO:0006941)3.94807541
79myofibril assembly (GO:0030239)3.93811284
80serine family amino acid metabolic process (GO:0009069)3.92761254
81aldehyde catabolic process (GO:0046185)3.92399968
82arginine metabolic process (GO:0006525)3.91798269
83cellular modified amino acid catabolic process (GO:0042219)3.90851065
84cellular polysaccharide catabolic process (GO:0044247)3.89608904
85cellular biogenic amine catabolic process (GO:0042402)3.89359535
86amine catabolic process (GO:0009310)3.89359535
87glutamate metabolic process (GO:0006536)3.89277983
88imidazole-containing compound metabolic process (GO:0052803)3.89030126
89ethanol oxidation (GO:0006069)3.88979579
90sarcomere organization (GO:0045214)3.88124372
91triglyceride catabolic process (GO:0019433)3.82654400
92low-density lipoprotein particle clearance (GO:0034383)3.82348440
93fatty acid transmembrane transport (GO:1902001)3.77296792
94response to muscle activity (GO:0014850)3.75293256
95ketone body metabolic process (GO:1902224)3.75100637
96plasma lipoprotein particle assembly (GO:0034377)3.73375978
97regulation of relaxation of muscle (GO:1901077)3.72473204
98positive regulation of lipid catabolic process (GO:0050996)3.71220627
99acetyl-CoA metabolic process (GO:0006084)3.70474465
100response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.70017092
101serine family amino acid biosynthetic process (GO:0009070)3.68983837
102cofactor catabolic process (GO:0051187)3.67243366
103glucuronate metabolic process (GO:0019585)3.66924155
104uronic acid metabolic process (GO:0006063)3.66924155
105complement activation, classical pathway (GO:0006958)3.66879650
106dicarboxylic acid biosynthetic process (GO:0043650)3.66739701
107gluconeogenesis (GO:0006094)3.64983583
108positive regulation of triglyceride lipase activity (GO:0061365)3.63312249
109positive regulation of lipoprotein lipase activity (GO:0051006)3.63312249
110epoxygenase P450 pathway (GO:0019373)3.62418385
111complement activation (GO:0006956)3.60321497
112negative regulation of lipase activity (GO:0060192)3.60160530
113acylglycerol catabolic process (GO:0046464)3.60026987
114neutral lipid catabolic process (GO:0046461)3.60026987
115regulation of cholesterol homeostasis (GO:2000188)3.59696030
116organic acid catabolic process (GO:0016054)3.58835221
117carboxylic acid catabolic process (GO:0046395)3.58835221
118cholesterol homeostasis (GO:0042632)3.58636674
119cytolysis (GO:0019835)3.58357790
120low-density lipoprotein particle remodeling (GO:0034374)3.57773059
121positive regulation of fatty acid beta-oxidation (GO:0032000)3.56990328
122sterol homeostasis (GO:0055092)3.53934213
123protein-lipid complex assembly (GO:0065005)3.53652410
124phospholipid homeostasis (GO:0055091)3.53162803
125response to nitrosative stress (GO:0051409)3.52665784
126polysaccharide catabolic process (GO:0000272)3.52287520
127regulation of bile acid biosynthetic process (GO:0070857)3.52236822
128regulation of plasminogen activation (GO:0010755)3.50929534
129protein activation cascade (GO:0072376)3.50779108
130blood coagulation, intrinsic pathway (GO:0007597)3.48497082
131exogenous drug catabolic process (GO:0042738)3.47231628
1322-oxoglutarate metabolic process (GO:0006103)3.46491648
133glucan biosynthetic process (GO:0009250)3.37304708
134glycogen biosynthetic process (GO:0005978)3.37304708
135fatty acid beta-oxidation (GO:0006635)3.37160759
136tricarboxylic acid cycle (GO:0006099)3.35335141
137regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.35000279
138hexose biosynthetic process (GO:0019319)3.34720920
139skeletal muscle fiber development (GO:0048741)3.32920426
140fatty acid catabolic process (GO:0009062)3.27953319
141response to mercury ion (GO:0046689)3.27509816
142daunorubicin metabolic process (GO:0044597)3.22400293
143polyketide metabolic process (GO:0030638)3.22400293
144doxorubicin metabolic process (GO:0044598)3.22400293
145ethanol metabolic process (GO:0006067)3.18995773
146* muscle contraction (GO:0006936)3.15296230
147actomyosin structure organization (GO:0031032)3.09569086
148carnitine transmembrane transport (GO:1902603)3.08731531
149monosaccharide biosynthetic process (GO:0046364)3.07563406
150carnitine transport (GO:0015879)3.07018447
151amino-acid betaine transport (GO:0015838)3.07018447
152cardiac myofibril assembly (GO:0055003)3.06143626
153fatty acid oxidation (GO:0019395)3.04507987
154cardiac muscle contraction (GO:0060048)3.01441729
155lipid oxidation (GO:0034440)2.99222634
156myotube cell development (GO:0014904)2.97546922
157monocarboxylic acid catabolic process (GO:0072329)2.95961133
158skeletal muscle adaptation (GO:0043501)2.95064764
159succinate metabolic process (GO:0006105)2.94271260
160tricarboxylic acid metabolic process (GO:0072350)2.93793791
161glycogen metabolic process (GO:0005977)2.89380651
162glucan metabolic process (GO:0044042)2.86522390
163cellular glucan metabolic process (GO:0006073)2.86522390
164omega-hydroxylase P450 pathway (GO:0097267)2.84764809
165response to inactivity (GO:0014854)2.83234465
166plasma membrane repair (GO:0001778)2.83029728

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse7.98675425
2PPARA_22158963_ChIP-Seq_LIVER_Mouse6.88384526
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.25872361
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.24027827
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.15276002
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.85535232
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.55911049
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.01298247
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.54455739
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.77643498
11TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.50296772
12CLOCK_20551151_ChIP-Seq_293T_Human2.15701216
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.3405617
14HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.91051511
15TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.88830626
16CDX2_19796622_ChIP-Seq_MESCs_Mouse1.84030320
17RARG_19884340_ChIP-ChIP_MEFs_Mouse1.74043911
18STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.71958436
19FOXA2_19822575_ChIP-Seq_HepG2_Human1.64092534
20TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.57011055
21TP63_17297297_ChIP-ChIP_HaCaT_Human1.48566444
22PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.43566192
23THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.38800509
24HNF4A_19822575_ChIP-Seq_HepG2_Human1.37506983
25HTT_18923047_ChIP-ChIP_STHdh_Human1.32015391
26GATA1_22025678_ChIP-Seq_K562_Human1.31600660
27RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.29516377
28NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.28766809
29ESR1_20079471_ChIP-ChIP_T-47D_Human1.27441068
30TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26019388
31TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.22966781
32MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.19406704
33ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.16932432
34NFIB_24661679_ChIP-Seq_LUNG_Mouse1.16543168
35P63_26484246_Chip-Seq_KERATINOCYTES_Human1.16165888
36STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.13072883
37ESR2_21235772_ChIP-Seq_MCF-7_Human1.10208607
38GATA4_21415370_ChIP-Seq_HL-1_Mouse1.08378802
39* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.06398854
40ZNF263_19887448_ChIP-Seq_K562_Human1.05684450
41ESR1_15608294_ChIP-ChIP_MCF-7_Human1.04827760
42CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.04392711
43HIF1A_21447827_ChIP-Seq_MCF-7_Human1.02997717
44KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.02453246
45CTCF_27219007_Chip-Seq_Bcells_Human1.01313129
46SOX2_27498859_Chip-Seq_STOMACH_Mouse1.01191976
47ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01150007
48SMC3_22415368_ChIP-Seq_MEFs_Mouse1.00959729
49GATA2_21666600_ChIP-Seq_HMVEC_Human0.98377803
50ESR1_21235772_ChIP-Seq_MCF-7_Human0.96842044
51SALL4_18804426_ChIP-ChIP_XEN_Mouse0.96393962
52ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.95383063
53TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93946325
54GATA4_25053715_ChIP-Seq_YYC3_Human0.93394510
55* ELK3_25401928_ChIP-Seq_HUVEC_Human0.92934714
56CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.91154903
57AUTS2_25519132_ChIP-Seq_293T-REX_Human0.90433496
58BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.89581659
59PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.89442578
60LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.88909030
61NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.87198009
62NRF2_20460467_ChIP-Seq_MEFs_Mouse0.87198009
63EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.84203761
64PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.83788308
65PPAR_26484153_Chip-Seq_NCI-H1993_Human0.82214064
66MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.82068566
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.81949686
68CTCF_27219007_Chip-Seq_ERYTHROID_Human0.80965007
69BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.80136843
70AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.79896034
71TET1_21451524_ChIP-Seq_MESCs_Mouse0.79322219
72SA1_27219007_Chip-Seq_Bcells_Human0.79063196
73CDX2_20551321_ChIP-Seq_CACO-2_Human0.78799582
74DNAJC2_21179169_ChIP-ChIP_NT2_Human0.77149376
75GATA1_19941827_ChIP-Seq_MEL_Mouse0.76430960
76SMC1_22415368_ChIP-Seq_MEFs_Mouse0.76162470
77SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.75061600
78LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.74178090
79SOX9_24532713_ChIP-Seq_HFSC_Mouse0.73500876
80KAP1_22055183_ChIP-Seq_ESCs_Mouse0.72373277
81TBX20_22328084_ChIP-Seq_HEART_Mouse0.71917689
82TBX20_22080862_ChIP-Seq_HEART_Mouse0.71917689
83Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.67710335
84FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.67056983
85RARA_24833708_ChIP-Seq_LIVER_Mouse0.66452718
86TRIM28_21343339_ChIP-Seq_HEK293_Human0.66066330
87IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.65467558
88FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.65449073
89PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.64233544
90FOXO3_23340844_ChIP-Seq_DLD1_Human0.63902107
91ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.63758527
92CEBPB_22108803_ChIP-Seq_LS180_Human0.63142214
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.62680118
94GATA6_25053715_ChIP-Seq_YYC3_Human0.60986298
95EP300_21415370_ChIP-Seq_HL-1_Mouse0.60112967
96FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.60098347
97SOX2_20726797_ChIP-Seq_SW620_Human0.59995343
98SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.59434764
99RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.58151500
100PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.57723844
101* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.57697291
102* CJUN_26792858_Chip-Seq_BT549_Human0.55893393
103RAD21_21589869_ChIP-Seq_MESCs_Mouse0.55354341
104ATF3_27146783_Chip-Seq_COLON_Human0.54543833
105NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.53964864
106RACK7_27058665_Chip-Seq_MCF-7_Human0.53565536
107GATA3_24758297_ChIP-Seq_MCF-7_Human0.52907524
108FOXA1_25552417_ChIP-Seq_VCAP_Human0.52755339
109RARB_24833708_ChIP-Seq_LIVER_Mouse0.52219785
110CDX2_22108803_ChIP-Seq_LS180_Human0.52027837
111AR_20517297_ChIP-Seq_VCAP_Human0.51365833
112CBP_21632823_ChIP-Seq_H3396_Human0.50825455
113BCAT_22108803_ChIP-Seq_LS180_Human0.50436574
114STAT3_1855785_ChIP-Seq_MESCs_Mouse0.49943106
115STAT1_17558387_ChIP-Seq_HELA_Human0.49659130
116LXR_22292898_ChIP-Seq_THP-1_Human0.49163144
117EGR1_19032775_ChIP-ChIP_M12_Human0.48860275
118ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.47908345
119ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.46905216
120KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.46449342
121NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.45382629
122TP63_23658742_ChIP-Seq_EP156T_Human0.44695193
123OCT4_20526341_ChIP-Seq_ESCs_Human0.44455825
124FOXH1_21741376_ChIP-Seq_EPCs_Human0.44429804
125ESET_19884257_ChIP-Seq_ESCs_Mouse0.43385431
126GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.42973078
127* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.42268046
128P53_21459846_ChIP-Seq_SAOS-2_Human0.42042660
129STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.41262602
130AR_21909140_ChIP-Seq_LNCAP_Human0.38745797
131* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.38670713
132LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.38116566
133BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.37945520

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system7.98192924
2MP0005360_urolithiasis7.08796007
3MP0005085_abnormal_gallbladder_physiolo6.22034487
4MP0005365_abnormal_bile_salt5.92503458
5MP0008875_abnormal_xenobiotic_pharmacok4.86521307
6MP0003806_abnormal_nucleotide_metabolis4.31381627
7MP0003252_abnormal_bile_duct3.87168190
8MP0010329_abnormal_lipoprotein_level3.33299522
9MP0005083_abnormal_biliary_tract3.24628431
10MP0009840_abnormal_foam_cell3.21767412
11MP0005332_abnormal_amino_acid2.57231000
12MP0003195_calcinosis2.50499517
13MP0000759_abnormal_skeletal_muscle2.44848748
14MP0002106_abnormal_muscle_physiology2.44838967
15MP0001666_abnormal_nutrient_absorption2.43737100
16MP0004084_abnormal_cardiac_muscle2.19290424
17MP0005369_muscle_phenotype2.08122799
18MP0003191_abnormal_cellular_cholesterol2.07837025
19MP0002332_abnormal_exercise_endurance2.06414896
20MP0000609_abnormal_liver_physiology2.02880406
21MP0002118_abnormal_lipid_homeostasis1.97090767
22MP0002138_abnormal_hepatobiliary_system1.93287721
23MP0005375_adipose_tissue_phenotype1.91246370
24MP0000750_abnormal_muscle_regeneration1.90339796
25MP0003868_abnormal_feces_composition1.87704053
26MP0005451_abnormal_body_composition1.85485346
27MP0003705_abnormal_hypodermis_morpholog1.82287747
28MP0004233_abnormal_muscle_weight1.80479377
29MP0004185_abnormal_adipocyte_glucose1.78883020
30MP0005319_abnormal_enzyme/_coenzyme1.77291704
31MP0002972_abnormal_cardiac_muscle1.76299933
32MP0004019_abnormal_vitamin_homeostasis1.74253136
33MP0000013_abnormal_adipose_tissue1.73908666
34MP0009697_abnormal_copulation1.72003379
35MP0009780_abnormal_chondrocyte_physiolo1.53865401
36MP0000003_abnormal_adipose_tissue1.47833522
37MP0005584_abnormal_enzyme/coenzyme_acti1.43906737
38MP0001764_abnormal_homeostasis1.40039342
39MP0002108_abnormal_muscle_morphology1.35514959
40MP0004215_abnormal_myocardial_fiber1.33931566
41MP0000733_abnormal_muscle_development1.32614014
42MP0004510_myositis1.29003386
43MP0003950_abnormal_plasma_membrane1.28342704
44MP0005385_cardiovascular_system_phenoty1.26316740
45MP0001544_abnormal_cardiovascular_syste1.26316740
46MP0010630_abnormal_cardiac_muscle1.26043508
47MP0003656_abnormal_erythrocyte_physiolo1.21392123
48MP0010368_abnormal_lymphatic_system1.21187545
49MP0005058_abnormal_lysosome_morphology1.19933269
50MP0009643_abnormal_urine_homeostasis1.18266728
51MP0004484_altered_response_of1.17693526
52MP0003186_abnormal_redox_activity1.16264567
53MP0000598_abnormal_liver_morphology1.15274801
54MP0003011_delayed_dark_adaptation1.08588818
55MP0008775_abnormal_heart_ventricle1.05612848
56MP0002837_dystrophic_cardiac_calcinosis1.04480298
57MP0005408_hypopigmentation1.00959803
58MP0005647_abnormal_sex_gland1.00738622
59MP0004272_abnormal_basement_membrane0.98333665
60MP0004130_abnormal_muscle_cell0.97639735
61MP0002127_abnormal_cardiovascular_syste0.93707340
62MP0006036_abnormal_mitochondrial_physio0.93506739
63MP0003959_abnormal_lean_body0.91014385
64MP0009764_decreased_sensitivity_to0.87719401
65MP0003879_abnormal_hair_cell0.86489906
66MP0000604_amyloidosis0.85932741
67MP0009763_increased_sensitivity_to0.85447665
68MP0003828_pulmonary_edema0.84682832
69MP0002971_abnormal_brown_adipose0.84602068
70MP0005670_abnormal_white_adipose0.83611584
71MP0008438_abnormal_cutaneous_collagen0.81660869
72MP0003718_maternal_effect0.80844909
73MP0005084_abnormal_gallbladder_morpholo0.80818687
74MP0002269_muscular_atrophy0.80305223
75MP0000749_muscle_degeneration0.79342288
76MP0009384_cardiac_valve_regurgitation0.78899800
77MP0005220_abnormal_exocrine_pancreas0.78796135
78MP0005636_abnormal_mineral_homeostasis0.78678207
79MP0002078_abnormal_glucose_homeostasis0.78363203
80MP0009642_abnormal_blood_homeostasis0.76992465
81MP0009053_abnormal_anal_canal0.76325899
82MP0005376_homeostasis/metabolism_phenot0.75701266
83MP0005165_increased_susceptibility_to0.73503656
84MP0005452_abnormal_adipose_tissue0.71140524
85MP0003221_abnormal_cardiomyocyte_apopto0.70635330
86MP0005395_other_phenotype0.70204497
87MP0002254_reproductive_system_inflammat0.68858697
88MP0004782_abnormal_surfactant_physiolog0.68477712
89MP0005266_abnormal_metabolism0.67066135
90MP0005334_abnormal_fat_pad0.66201284
91MP0008469_abnormal_protein_level0.66183601
92MP0000343_altered_response_to0.64398528
93MP0003075_altered_response_to0.62857223
94MP0000639_abnormal_adrenal_gland0.61918564
95MP0003137_abnormal_impulse_conducting0.61068918
96MP0001756_abnormal_urination0.59720222
97MP0002822_catalepsy0.58610328
98MP0003329_amyloid_beta_deposits0.56218650
99MP0005330_cardiomyopathy0.55818006
100MP0000747_muscle_weakness0.55808292
101MP0004087_abnormal_muscle_fiber0.55018016
102MP0003566_abnormal_cell_adhesion0.54587979
103MP0009765_abnormal_xenobiotic_induced0.54175878
104MP0001661_extended_life_span0.53733304
105MP0002928_abnormal_bile_duct0.53180001
106MP0006035_abnormal_mitochondrial_morpho0.52803929
107MP0003646_muscle_fatigue0.51971695
108MP0005666_abnormal_adipose_tissue0.51383742
109MP0005275_abnormal_skin_tensile0.51113660
110MP0004036_abnormal_muscle_relaxation0.50289908
111MP0002896_abnormal_bone_mineralization0.47477100
112MP0002168_other_aberrant_phenotype0.46948018
113MP0002295_abnormal_pulmonary_circulatio0.46927030
114MP0005023_abnormal_wound_healing0.46887594
115MP0003279_aneurysm0.46839295
116MP0005448_abnormal_energy_balance0.46431259
117MP0004085_abnormal_heartbeat0.46026891
118MP0005248_abnormal_Harderian_gland0.45809435
119MP0005535_abnormal_body_temperature0.45161628
120MP0009672_abnormal_birth_weight0.44810526
121MP0000579_abnormal_nail_morphology0.44505780
122MP0001542_abnormal_bone_strength0.43291253
123MP0002060_abnormal_skin_morphology0.43123263
124MP0001243_abnormal_dermal_layer0.43057216
125MP0000230_abnormal_systemic_arterial0.42276871
126MP0000751_myopathy0.41295340
127MP0009115_abnormal_fat_cell0.40886376
128MP0004883_abnormal_blood_vessel0.39155975
129MP0004145_abnormal_muscle_electrophysio0.38466605
130MP0005620_abnormal_muscle_contractility0.37387469
131MP0002970_abnormal_white_adipose0.35630885
132MP0002876_abnormal_thyroid_physiology0.35330292
133MP0001915_intracranial_hemorrhage0.34903144
134MP0002136_abnormal_kidney_physiology0.34588199
135MP0003953_abnormal_hormone_level0.33216825
136MP0005166_decreased_susceptibility_to0.33201722
137MP0000249_abnormal_blood_vessel0.32031020
138MP0002128_abnormal_blood_circulation0.31202036
139MP0003699_abnormal_female_reproductive0.30928023
140MP0006138_congestive_heart_failure0.30927745

Predicted human phenotypes

RankGene SetZ-score
1Nemaline bodies (HP:0003798)8.27881462
2Deep venous thrombosis (HP:0002625)7.59562883
3Abnormality of aromatic amino acid family metabolism (HP:0004338)6.95407499
4Exercise-induced myalgia (HP:0003738)6.83168196
5Intrahepatic cholestasis (HP:0001406)6.74267930
6Abnormality of monocarboxylic acid metabolism (HP:0010996)6.12746164
7Xanthomatosis (HP:0000991)5.96814707
8Hypobetalipoproteinemia (HP:0003563)5.92883578
9Prolonged partial thromboplastin time (HP:0003645)5.82920740
10Exercise-induced muscle cramps (HP:0003710)5.37855046
11Complement deficiency (HP:0004431)5.24954630
12Hyperlipoproteinemia (HP:0010980)4.97852714
13Distal arthrogryposis (HP:0005684)4.70387982
14Hypolipoproteinemia (HP:0010981)4.66797119
15Muscle hypertrophy of the lower extremities (HP:0008968)4.55846513
16Hyperammonemia (HP:0001987)4.35591735
17EMG: myopathic abnormalities (HP:0003458)4.33985894
18Myopathic facies (HP:0002058)4.33653829
19Hypoalphalipoproteinemia (HP:0003233)4.28627386
20Round ear (HP:0100830)4.23941883
21Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.16974460
22Abnormality of the common coagulation pathway (HP:0010990)4.15552829
23Epidermoid cyst (HP:0200040)4.11839621
24Joint hemorrhage (HP:0005261)4.11757095
25Calf muscle hypertrophy (HP:0008981)4.09757602
26Hyporeflexia of lower limbs (HP:0002600)4.09377730
27Ketosis (HP:0001946)4.08260666
28Hyperglycinemia (HP:0002154)4.07142187
29Abnormality of skeletal muscle fiber size (HP:0012084)4.06129059
30Centrally nucleated skeletal muscle fibers (HP:0003687)3.91459335
31Ulnar deviation of the wrist (HP:0003049)3.90699185
32Muscle fiber splitting (HP:0003555)3.90655065
33Neck muscle weakness (HP:0000467)3.88345603
34Abnormality of glutamine family amino acid metabolism (HP:0010902)3.85856906
35Abnormality of methionine metabolism (HP:0010901)3.85410666
36Fat malabsorption (HP:0002630)3.82359781
37Abnormality of complement system (HP:0005339)3.81652230
38Abnormality of sulfur amino acid metabolism (HP:0004339)3.80982220
39Hypoglycemic coma (HP:0001325)3.79383297
40Abnormality of aspartate family amino acid metabolism (HP:0010899)3.73656975
41Distal lower limb muscle weakness (HP:0009053)3.72926282
42Abnormality of the calf musculature (HP:0001430)3.65830043
43Asymmetric septal hypertrophy (HP:0001670)3.65542856
44Increased variability in muscle fiber diameter (HP:0003557)3.61475335
45Abnormality of the intrinsic pathway (HP:0010989)3.60732275
46Abnormality of serine family amino acid metabolism (HP:0010894)3.55013714
47Abnormality of glycine metabolism (HP:0010895)3.55013714
48Hyperglycinuria (HP:0003108)3.54457621
49Increased connective tissue (HP:0009025)3.49260148
50Difficulty running (HP:0009046)3.37168541
51Muscle stiffness (HP:0003552)3.34350208
52Abnormality of fatty-acid metabolism (HP:0004359)3.31492575
53Hypercholesterolemia (HP:0003124)3.29784378
54Abnormality of pyrimidine metabolism (HP:0004353)3.29243999
55Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.24589656
56Rimmed vacuoles (HP:0003805)3.23766251
57Conjugated hyperbilirubinemia (HP:0002908)3.10353660
58Hyperbilirubinemia (HP:0002904)3.02714117
59Sudden death (HP:0001699)3.01179599
60Subaortic stenosis (HP:0001682)3.00561708
61Abnormality of the left ventricular outflow tract (HP:0011103)3.00561708
62Hepatocellular carcinoma (HP:0001402)3.00232698
63Ketoacidosis (HP:0001993)2.95891476
64Cholecystitis (HP:0001082)2.92180955
65Abnormal gallbladder physiology (HP:0012438)2.92180955
66Abnormality of serum amino acid levels (HP:0003112)2.88254896
67Steatorrhea (HP:0002570)2.88227779
68Abnormality of nucleobase metabolism (HP:0010932)2.86334654
69Calcaneovalgus deformity (HP:0001848)2.85662485
70Myocardial infarction (HP:0001658)2.82368504
71Skin nodule (HP:0200036)2.74225008
72Bundle branch block (HP:0011710)2.73522756
73Abnormal gallbladder morphology (HP:0012437)2.72667789
74Mildly elevated creatine phosphokinase (HP:0008180)2.72586739
75Cholelithiasis (HP:0001081)2.72214525
76Hypochromic microcytic anemia (HP:0004840)2.71027826
77Absent phalangeal crease (HP:0006109)2.69157459
78Gout (HP:0001997)2.69053195
79Frequent falls (HP:0002359)2.67919708
80Abnormality of purine metabolism (HP:0004352)2.64879982
81Spontaneous abortion (HP:0005268)2.63849291
82Delayed CNS myelination (HP:0002188)2.60926824
83Metabolic acidosis (HP:0001942)2.59563420
84Distal lower limb amyotrophy (HP:0008944)2.54721119
85Ventricular tachycardia (HP:0004756)2.53430916
86Deformed tarsal bones (HP:0008119)2.51537068
87Abnormality of dicarboxylic acid metabolism (HP:0010995)2.49669356
88Dicarboxylic aciduria (HP:0003215)2.49669356
89Dilated cardiomyopathy (HP:0001644)2.46633901
90Systemic lupus erythematosus (HP:0002725)2.45606675
91Lethargy (HP:0001254)2.41369313
92Malignant hyperthermia (HP:0002047)2.41368370
93Gowers sign (HP:0003391)2.41033036
94Areflexia of lower limbs (HP:0002522)2.38813907
95Neonatal onset (HP:0003623)2.37936480
96Bulbar palsy (HP:0001283)2.37363684
97EMG: neuropathic changes (HP:0003445)2.34183494
98Myotonia (HP:0002486)2.29866420
99Spinal rigidity (HP:0003306)2.28526379
100Enlarged kidneys (HP:0000105)2.27716550
101Vascular calcification (HP:0004934)2.26773967
102Mitral stenosis (HP:0001718)2.26233351
103Late onset (HP:0003584)2.26130439
104Generalized muscle weakness (HP:0003324)2.25941184
105Cerebral edema (HP:0002181)2.24937268
106Slender build (HP:0001533)2.22943955
107Esophageal varix (HP:0002040)2.22461158
108Lipoatrophy (HP:0100578)2.21805729
109Malnutrition (HP:0004395)2.21218316
110Hypoglycemic seizures (HP:0002173)2.17267621
111Spastic diplegia (HP:0001264)2.14339723
112Scapular winging (HP:0003691)2.14259688
113Cardiovascular calcification (HP:0011915)2.13483269
114Glomerulonephritis (HP:0000099)2.11138034
115Abnormal finger flexion creases (HP:0006143)2.10920485
116Acanthocytosis (HP:0001927)2.10754081
117Abnormal atrioventricular conduction (HP:0005150)2.09966583
118Abnormality of the gallbladder (HP:0005264)2.08972424
119Hyperglycemia (HP:0003074)2.08291263
120Myoglobinuria (HP:0002913)2.07375708
121Oligomenorrhea (HP:0000876)2.07247856
122Limb-girdle muscle atrophy (HP:0003797)2.06367750
123Heart block (HP:0012722)2.05195865
124Irritability (HP:0000737)2.02429447
125Sensorimotor neuropathy (HP:0007141)2.01498714
126Abnormal cartilage morphology (HP:0002763)1.97716876
127Insulin-resistant diabetes mellitus (HP:0000831)1.96790877
128Generalized aminoaciduria (HP:0002909)1.93799624
129Amyloidosis (HP:0011034)1.92875758
130Brushfield spots (HP:0001088)1.92759773
131Abnormality of placental membranes (HP:0011409)1.92011873
132Amniotic constriction ring (HP:0009775)1.92011873
133Back pain (HP:0003418)1.89583846
134Increased purine levels (HP:0004368)1.88510746
135Hyperuricemia (HP:0002149)1.88510746
136Ragged-red muscle fibers (HP:0003200)1.88214917
137Pancreatitis (HP:0001733)1.87579123
138Abnormality of proline metabolism (HP:0010907)1.87521207
139Hydroxyprolinuria (HP:0003080)1.87521207
140Recurrent gram-negative bacterial infections (HP:0005420)1.86544195
141Progressive muscle weakness (HP:0003323)1.86486679
142Increased muscle lipid content (HP:0009058)1.85819135
143Type 1 muscle fiber predominance (HP:0003803)1.85064909
144Vomiting (HP:0002013)1.84576205
145Popliteal pterygium (HP:0009756)1.83449138
146Hemorrhage of the eye (HP:0011885)1.83117021
147Abnormality of the Achilles tendon (HP:0005109)1.82426716
148Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.81273201
149Rhabdomyolysis (HP:0003201)1.80153206
150Fetal akinesia sequence (HP:0001989)1.79659808
151Menorrhagia (HP:0000132)1.78590938
152Muscle fiber inclusion bodies (HP:0100299)1.78478363
153Increased serum pyruvate (HP:0003542)1.76926265
154Proximal tubulopathy (HP:0000114)1.76520582
155Difficulty climbing stairs (HP:0003551)1.75260690
156Abnormality of iron homeostasis (HP:0011031)1.74922955
157Hyperinsulinemic hypoglycemia (HP:0000825)1.73023143
158Atrioventricular block (HP:0001678)1.73000344
159Thrombophlebitis (HP:0004418)1.72956601
160Abnormality of transition element cation homeostasis (HP:0011030)1.71573840
161Hip contracture (HP:0003273)1.70831431
162Achilles tendon contracture (HP:0001771)1.69795202
163Weak cry (HP:0001612)1.69657362
164Abnormality of the calcaneus (HP:0008364)1.69384029
165Ventricular arrhythmia (HP:0004308)1.69334747
166Lower limb amyotrophy (HP:0007210)1.66700567

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK5.43729619
2ERN13.48729617
3FGFR43.45864865
4SIK13.45716457
5LATS13.27263383
6TRIB33.12759069
7TAOK33.06841455
8PKN22.75939866
9ERBB42.69617536
10STK38L2.60717333
11OBSCN2.54203572
12PIK3CG2.33162415
13LATS22.13859570
14MAP2K42.02945970
15NEK92.01105597
16MOS1.95097616
17FLT31.80898390
18INSRR1.73925290
19TESK11.68142815
20LIMK11.54007998
21MST1R1.53719794
22MAPK111.49017782
23EPHA31.35590122
24FRK1.34982363
25ABL21.34749056
26PTK61.32727236
27MAP2K31.31854659
28TTN1.18748731
29MAPKAPK31.18252483
30MAP3K71.15167103
31PRPF4B1.13659453
32PDK21.11929808
33KSR21.07160112
34PRKAA21.05145007
35PTK21.01457429
36MAP3K31.00851570
37MAP2K11.00284280
38STK30.94567151
39TAOK20.93139219
40PINK10.90041990
41NEK10.89019199
42IRAK30.89001379
43EEF2K0.86561659
44MET0.86473945
45DMPK0.85691259
46MAP3K100.85568178
47STK240.85525887
48RET0.84982341
49TYK20.83819540
50MAP3K60.82845172
51PDGFRA0.80259621
52ERBB20.79169928
53ICK0.77991907
54MAP3K110.73013760
55DAPK20.72971836
56PRKAA10.72391600
57SCYL20.72321918
58JAK20.72264210
59CAMK2G0.71274452
60MAPK120.71175840
61PIK3CA0.70871421
62PIM20.70224451
63CAMK2D0.70055967
64TGFBR20.69721691
65PHKG20.68497746
66PHKG10.68497746
67KDR0.67896544
68PDK40.67190821
69PDK30.67190821
70AKT20.67063229
71BMPR20.65164574
72PRKG20.64018105
73EPHB10.64007489
74CDK60.63208267
75MAP3K50.62337003
76MYLK0.62200119
77FGFR20.60564729
78TBK10.58159595
79PRKCZ0.57402589
80RIPK10.57089703
81MAPK70.55818763
82MAP2K60.55612572
83TIE10.54633496
84FER0.54390668
85MUSK0.54224161
86PRKG10.53517754
87MTOR0.53391547
88PAK30.51900016
89DDR20.51841692
90MAPK40.51197614
91MAP3K130.51065640
92JAK10.50518676
93CAMK10.47468590
94LRRK20.45289993
95NTRK10.44819235
96NUAK10.44158604
97MAP3K120.43116685
98PRKACG0.42445452
99PDK10.42438512
100PRKD10.42347655
101GSK3A0.42334610
102ARAF0.40538783
103CDC42BPA0.40236895
104TESK20.39093939
105DYRK1B0.37931933
106TRPM70.37855454
107CAMK2B0.37607313
108EPHA20.37370563
109PRKD20.36376032
110DAPK30.35874151
111ZAP700.35364157
112FGFR30.34667330
113EPHB20.33672446
114MAP3K20.33585949
115ROCK10.33377062
116SGK30.32860159
117NME10.32674889
118IGF1R0.30935242
119PRKACA0.30602135
120ILK0.30485965
121CSNK1G10.30479649
122CAMK40.29679303
123PAK20.28503053
124LMTK20.28429996
125MAPK150.26867073
126TAOK10.26477182
127CAMK1D0.25983845
128MAP3K10.25761850
129PDPK10.25596650
130STK100.24795168
131STK380.24323459

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.45011931
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.45993063
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.32465567
4Nitrogen metabolism_Homo sapiens_hsa009103.28662985
5Arginine biosynthesis_Homo sapiens_hsa002202.99417827
6Complement and coagulation cascades_Homo sapiens_hsa046102.78370200
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.68916686
8Tryptophan metabolism_Homo sapiens_hsa003802.68243635
9Fatty acid degradation_Homo sapiens_hsa000712.65954347
10Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.59562004
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.50054242
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.46644344
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.15705557
14Butanoate metabolism_Homo sapiens_hsa006502.07838295
15Propanoate metabolism_Homo sapiens_hsa006402.06335366
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.06214605
17Peroxisome_Homo sapiens_hsa041462.04883278
18PPAR signaling pathway_Homo sapiens_hsa033201.93666607
19Fatty acid metabolism_Homo sapiens_hsa012121.87494818
20Chemical carcinogenesis_Homo sapiens_hsa052041.86756271
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.83071267
22Histidine metabolism_Homo sapiens_hsa003401.78406580
23Steroid hormone biosynthesis_Homo sapiens_hsa001401.77262218
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.71239836
25Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.69159645
26Caffeine metabolism_Homo sapiens_hsa002321.68728194
27Drug metabolism - other enzymes_Homo sapiens_hsa009831.67192234
28beta-Alanine metabolism_Homo sapiens_hsa004101.66881936
29Retinol metabolism_Homo sapiens_hsa008301.59661896
30Staphylococcus aureus infection_Homo sapiens_hsa051501.59106456
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.59089063
32Pyruvate metabolism_Homo sapiens_hsa006201.55711864
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.54001118
34Selenocompound metabolism_Homo sapiens_hsa004501.53322638
35Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.52658961
36Phenylalanine metabolism_Homo sapiens_hsa003601.49585222
37Bile secretion_Homo sapiens_hsa049761.49575177
38Starch and sucrose metabolism_Homo sapiens_hsa005001.42251372
39Tyrosine metabolism_Homo sapiens_hsa003501.39890478
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.33178967
41Biosynthesis of amino acids_Homo sapiens_hsa012301.32140730
42Carbon metabolism_Homo sapiens_hsa012001.29317125
43Sulfur metabolism_Homo sapiens_hsa009201.26885175
44Fatty acid elongation_Homo sapiens_hsa000621.24116465
45Folate biosynthesis_Homo sapiens_hsa007901.22342393
46Cardiac muscle contraction_Homo sapiens_hsa042601.20430907
47Fat digestion and absorption_Homo sapiens_hsa049751.16474630
48Steroid biosynthesis_Homo sapiens_hsa001001.08325533
49ABC transporters_Homo sapiens_hsa020101.05786631
50Arginine and proline metabolism_Homo sapiens_hsa003301.02351161
51Vitamin B6 metabolism_Homo sapiens_hsa007501.02042187
52Maturity onset diabetes of the young_Homo sapiens_hsa049500.95506111
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.95359122
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.90250749
55Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.88311206
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87008617
57Sulfur relay system_Homo sapiens_hsa041220.86684761
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.83198484
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.81602854
60Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.81064977
61Lysine degradation_Homo sapiens_hsa003100.78216233
62Other glycan degradation_Homo sapiens_hsa005110.72913458
63Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72587093
64Glutathione metabolism_Homo sapiens_hsa004800.69823405
65Vitamin digestion and absorption_Homo sapiens_hsa049770.69167414
66One carbon pool by folate_Homo sapiens_hsa006700.66225089
67Glycerolipid metabolism_Homo sapiens_hsa005610.65516289
68Renin-angiotensin system_Homo sapiens_hsa046140.64279784
69Pentose phosphate pathway_Homo sapiens_hsa000300.61746625
70Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.50185643
71Fatty acid biosynthesis_Homo sapiens_hsa000610.49102685
72Metabolic pathways_Homo sapiens_hsa011000.43310783
73Prion diseases_Homo sapiens_hsa050200.42495346
74Insulin resistance_Homo sapiens_hsa049310.39997579
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.35215315
76Mineral absorption_Homo sapiens_hsa049780.35091455
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.32448200
78Galactose metabolism_Homo sapiens_hsa000520.31975800
79Renin secretion_Homo sapiens_hsa049240.30971428
80Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.30106485
81cGMP-PKG signaling pathway_Homo sapiens_hsa040220.29836930
82Vascular smooth muscle contraction_Homo sapiens_hsa042700.28527003
83Glucagon signaling pathway_Homo sapiens_hsa049220.28422280
84alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25200869
85Fructose and mannose metabolism_Homo sapiens_hsa000510.24820144
86Focal adhesion_Homo sapiens_hsa045100.24601987
87Alzheimers disease_Homo sapiens_hsa050100.23408811
88Linoleic acid metabolism_Homo sapiens_hsa005910.22737604
89Ovarian steroidogenesis_Homo sapiens_hsa049130.22590610
90Tight junction_Homo sapiens_hsa045300.19891018
91AMPK signaling pathway_Homo sapiens_hsa041520.16916566
92Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.16090510
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.12959179
94Insulin signaling pathway_Homo sapiens_hsa049100.10391702
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.00939358
96Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.00522735
97Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.00461293
98Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.00135059
99ECM-receptor interaction_Homo sapiens_hsa04512-0.1904179
100FoxO signaling pathway_Homo sapiens_hsa04068-0.1830451
101Dilated cardiomyopathy_Homo sapiens_hsa05414-0.1744523
102Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1739797
103Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412-0.1649385
104Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1546659
105Protein digestion and absorption_Homo sapiens_hsa04974-0.1507052
106Regulation of autophagy_Homo sapiens_hsa04140-0.1352115
107Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.1138250
108Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410-0.1013204
109Circadian rhythm_Homo sapiens_hsa04710-0.0973336
110Amoebiasis_Homo sapiens_hsa05146-0.0773515
111Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0677717
112Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.0647665
113Bladder cancer_Homo sapiens_hsa05219-0.0506828

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