STK11IP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to peptidoglycan (GO:0032494)4.85343338
2positive thymic T cell selection (GO:0045059)4.75407271
3positive regulation of gamma-delta T cell activation (GO:0046645)4.72397216
4B cell receptor signaling pathway (GO:0050853)4.54365697
5mannose metabolic process (GO:0006013)4.18009570
6detection of other organism (GO:0098543)3.82633150
7regulation of gamma-delta T cell differentiation (GO:0045586)3.77865902
8detection of bacterium (GO:0016045)3.77564947
9antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.64614479
10positive regulation of B cell differentiation (GO:0045579)3.63323971
11negative regulation of interleukin-12 production (GO:0032695)3.62494512
12regulation of gamma-delta T cell activation (GO:0046643)3.61058458
13regulation of B cell receptor signaling pathway (GO:0050855)3.58611572
14regulation of T-helper 2 cell differentiation (GO:0045628)3.46426849
15positive T cell selection (GO:0043368)3.45161436
16regulation of leukocyte degranulation (GO:0043300)3.44116587
17regulation of mast cell degranulation (GO:0043304)3.36213162
18negative thymic T cell selection (GO:0045060)3.34579199
19regulation of B cell differentiation (GO:0045577)3.33238125
20translesion synthesis (GO:0019985)3.32921733
21cellular extravasation (GO:0045123)3.31604725
22negative regulation of cell killing (GO:0031342)3.30810163
23negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.30810163
24regulation of myeloid leukocyte mediated immunity (GO:0002886)3.29010253
25NIK/NF-kappaB signaling (GO:0038061)3.28701691
26positive regulation of gene expression, epigenetic (GO:0045815)3.28399873
27germinal center formation (GO:0002467)3.24955207
28pre-miRNA processing (GO:0031054)3.24450287
29negative T cell selection (GO:0043383)3.18799402
30regulation of chromatin binding (GO:0035561)3.13385176
31thymic T cell selection (GO:0045061)3.08130544
32detection of external biotic stimulus (GO:0098581)3.08010089
33lipopolysaccharide-mediated signaling pathway (GO:0031663)3.06321315
34positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.05423154
35DNA unwinding involved in DNA replication (GO:0006268)3.04265106
36modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.02580609
37positive regulation by organism of defense response of other organism involved in symbiotic interact3.02580609
38modulation by symbiont of host immune response (GO:0052553)3.02580609
39positive regulation by symbiont of host defense response (GO:0052509)3.02580609
40modulation by symbiont of host defense response (GO:0052031)3.02580609
41modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.02580609
42antigen processing and presentation of endogenous antigen (GO:0019883)3.01109089
43positive regulation of oligodendrocyte differentiation (GO:0048714)2.99122277
44positive regulation of type 2 immune response (GO:0002830)2.98645522
45leukocyte aggregation (GO:0070486)2.97971915
46negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.97264107
47B cell homeostasis (GO:0001782)2.96995290
48regulation of mast cell activation involved in immune response (GO:0033006)2.95189074
49negative regulation of histone methylation (GO:0031061)2.93067839
50response to laminar fluid shear stress (GO:0034616)2.91555023
51negative regulation of leukocyte mediated immunity (GO:0002704)2.87694461
52macrophage activation involved in immune response (GO:0002281)2.87200672
53negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.86435809
54negative regulation of lymphocyte mediated immunity (GO:0002707)2.84484368
55detection of biotic stimulus (GO:0009595)2.84201976
56epithelial cell differentiation involved in prostate gland development (GO:0060742)2.82917350
57regulation of interferon-beta biosynthetic process (GO:0045357)2.82191301
58response to host immune response (GO:0052572)2.78912849
59response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.78912849
60response to host (GO:0075136)2.77936935
61response to host defenses (GO:0052200)2.77936935
62response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.77936935
63regulation of superoxide anion generation (GO:0032928)2.77105628
64positive regulation of Cdc42 GTPase activity (GO:0043089)2.76616401
65regulation of regulated secretory pathway (GO:1903305)2.75946965
66regulation of type 2 immune response (GO:0002828)2.75884395
67negative regulation of toll-like receptor signaling pathway (GO:0034122)2.75623140
68tolerance induction (GO:0002507)2.75214992
69negative regulation of RNA splicing (GO:0033119)2.74700919
70regulation of tolerance induction (GO:0002643)2.72887560
71regulation of NFAT protein import into nucleus (GO:0051532)2.71685355
72negative regulation of granulocyte differentiation (GO:0030853)2.71253553
73negative regulation of B cell proliferation (GO:0030889)2.71121071
74neutrophil activation involved in immune response (GO:0002283)2.71086638
75T cell selection (GO:0045058)2.70948886
76histone H3-K4 methylation (GO:0051568)2.70654976
77determination of adult lifespan (GO:0008340)2.69972354
78pinocytosis (GO:0006907)2.67478111
79detection of molecule of bacterial origin (GO:0032490)2.67468813
80negative regulation of cytokine production involved in immune response (GO:0002719)2.66960547
81antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.65373394
82antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.65373394
83regulation of type I interferon-mediated signaling pathway (GO:0060338)2.65036467
84macrophage activation (GO:0042116)2.63326286
85protein-DNA complex disassembly (GO:0032986)2.62723775
86nucleosome disassembly (GO:0006337)2.62723775
87modulation by symbiont of host cellular process (GO:0044068)2.61590604
88protein localization to endosome (GO:0036010)2.61545956
89negative regulation of myeloid cell apoptotic process (GO:0033033)2.61177463
90negative regulation of type 2 immune response (GO:0002829)2.60980347
91regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.60721690
92regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.59196282
93type I interferon signaling pathway (GO:0060337)2.58520534
94cellular response to type I interferon (GO:0071357)2.58520534
95response to type I interferon (GO:0034340)2.57618889
96histone H3-K36 demethylation (GO:0070544)2.57272787
97barbed-end actin filament capping (GO:0051016)2.56675560
98modulation by virus of host process (GO:0019054)2.56494672
99spliceosomal tri-snRNP complex assembly (GO:0000244)2.55651302
100neutrophil activation (GO:0042119)2.55427442
101positive regulation of cellular amide metabolic process (GO:0034250)2.55101272
102positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.54038542
103positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.53134390
104regulation of histone H3-K4 methylation (GO:0051569)2.51353040
105histone H3-K4 trimethylation (GO:0080182)2.50972978
106antigen receptor-mediated signaling pathway (GO:0050851)2.50920276
107negative regulation of mRNA processing (GO:0050686)2.50899586
108negative regulation of gene expression, epigenetic (GO:0045814)2.48918875
109response to muramyl dipeptide (GO:0032495)2.48641635
1103-UTR-mediated mRNA stabilization (GO:0070935)2.48082417
111histone H2A acetylation (GO:0043968)2.46271285
112antigen processing and presentation via MHC class Ib (GO:0002475)2.45948031
113intracellular estrogen receptor signaling pathway (GO:0030520)2.45810206
114positive regulation of histone H3-K4 methylation (GO:0051571)2.45702497
115granulocyte activation (GO:0036230)2.44902859
116amyloid precursor protein catabolic process (GO:0042987)2.43404197
117negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.43126649
118negative regulation of translation, ncRNA-mediated (GO:0040033)2.43126649
119regulation of translation, ncRNA-mediated (GO:0045974)2.43126649
120dosage compensation (GO:0007549)2.42892470
121B cell proliferation (GO:0042100)2.42839175
122regulation of monocyte differentiation (GO:0045655)2.42140244
123regulation of dendritic cell antigen processing and presentation (GO:0002604)2.40904996
124positive regulation of RNA splicing (GO:0033120)2.40386080
125positive regulation of mast cell activation (GO:0033005)2.40053384
126response to protozoan (GO:0001562)2.39715308
127negative regulation of interleukin-8 production (GO:0032717)2.39168440
128defense response to protozoan (GO:0042832)2.39090834
129CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.38958861
130stress fiber assembly (GO:0043149)2.38438668
131regulation of histone methylation (GO:0031060)2.37123408
132chromatin silencing (GO:0006342)2.33878552
133myeloid cell activation involved in immune response (GO:0002275)2.33396698
134alternative mRNA splicing, via spliceosome (GO:0000380)2.33374618
135negative regulation of mRNA metabolic process (GO:1903312)2.33359037
136positive regulation of Rap GTPase activity (GO:0032854)2.32762198
137mast cell activation (GO:0045576)2.32758455
138lymphocyte homeostasis (GO:0002260)2.32446266
139negative regulation of erythrocyte differentiation (GO:0045647)2.30369462
140regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.29711216
141mRNA splice site selection (GO:0006376)2.29623110
142peptidyl-arginine omega-N-methylation (GO:0035247)2.29483199
143regulation of ARF GTPase activity (GO:0032312)2.28761429
144T cell homeostasis (GO:0043029)2.26023426
145negative regulation of interleukin-6 production (GO:0032715)2.25754085
146immunoglobulin mediated immune response (GO:0016064)2.23939831
147telomere maintenance via semi-conservative replication (GO:0032201)2.23657435
148regulation of histone H3-K9 methylation (GO:0051570)2.23442972
149respiratory burst (GO:0045730)2.23148170
150negative regulation of gene silencing (GO:0060969)2.22429601
151mature B cell differentiation (GO:0002335)2.22366316
152DNA strand elongation involved in DNA replication (GO:0006271)2.21439354
153megakaryocyte development (GO:0035855)2.20542242
154negative regulation of chromatin modification (GO:1903309)2.18593364
155positive regulation of leukocyte degranulation (GO:0043302)2.18304273
156positive regulation of isotype switching (GO:0045830)2.18103905
157regulation of chromatin silencing (GO:0031935)2.16627970
158immune response-activating cell surface receptor signaling pathway (GO:0002429)2.16351288
159positive regulation of histone deacetylation (GO:0031065)2.15449615
160mononuclear cell proliferation (GO:0032943)2.14205130
161positive regulation of mast cell activation involved in immune response (GO:0033008)2.13587039
162positive regulation of mast cell degranulation (GO:0043306)2.13587039
163lymphocyte proliferation (GO:0046651)2.12875135

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.02852711
2MYC_22102868_ChIP-Seq_BL_Human3.88524463
3VDR_21846776_ChIP-Seq_THP-1_Human3.36357613
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.34967310
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.30267934
6SCL_19346495_ChIP-Seq_HPC-7_Human2.87018616
7THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.81136403
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.76873641
9CIITA_25753668_ChIP-Seq_RAJI_Human2.61010599
10IRF8_21731497_ChIP-ChIP_J774_Mouse2.58557388
11STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.58228957
12* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.53593801
13IRF8_22096565_ChIP-ChIP_GC-B_Human2.48997358
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.44145382
15TCF7_22412390_ChIP-Seq_EML_Mouse2.33958504
16FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.28725968
17NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.22435006
18MAF_26560356_Chip-Seq_TH1_Human2.19254100
19E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.12871945
20KDM2B_26808549_Chip-Seq_DND41_Human2.07171430
21UTX_26944678_Chip-Seq_JUKART_Human2.05210627
22E2F4_17652178_ChIP-ChIP_JURKAT_Human2.02013174
23VDR_24763502_ChIP-Seq_THP-1_Human2.01257283
24TP63_17297297_ChIP-ChIP_HaCaT_Human1.99572628
25KDM2B_26808549_Chip-Seq_SUP-B15_Human1.98658869
26IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.98631775
27RACK7_27058665_Chip-Seq_MCF-7_Human1.97737794
28IRF8_27001747_Chip-Seq_BMDM_Mouse1.96805271
29* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.93259377
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.88363592
31SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.88084545
32* SPI1_23127762_ChIP-Seq_K562_Human1.86648802
33BP1_19119308_ChIP-ChIP_Hs578T_Human1.86525306
34MYB_26560356_Chip-Seq_TH2_Human1.86080486
35* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.85223858
36KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.83305841
37* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.82901944
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.78963036
39MYB_26560356_Chip-Seq_TH1_Human1.78760975
40RUNX1_22412390_ChIP-Seq_EML_Mouse1.78495317
41* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.76510844
42RUNX_20019798_ChIP-Seq_JUKART_Human1.75335116
43RARG_19884340_ChIP-ChIP_MEFs_Mouse1.71397535
44* SPI1_23547873_ChIP-Seq_NB4_Human1.67615021
45RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.64025585
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62570402
47* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.62438445
48CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.59910216
49ELK3_25401928_ChIP-Seq_HUVEC_Human1.56712283
50SA1_27219007_Chip-Seq_ERYTHROID_Human1.56513046
51STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.54737598
52MAF_26560356_Chip-Seq_TH2_Human1.51517800
53SMC4_20622854_ChIP-Seq_HELA_Human1.50758973
54GATA1_22025678_ChIP-Seq_K562_Human1.50057727
55ELF1_20517297_ChIP-Seq_JURKAT_Human1.48338850
56MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.47314653
57MYB_21317192_ChIP-Seq_ERMYB_Mouse1.46283064
58CTCF_27219007_Chip-Seq_ERYTHROID_Human1.45238442
59PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.43579536
60TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.43174960
61TFEB_21752829_ChIP-Seq_HELA_Human1.41416493
62* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.40288409
63NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.40274312
64EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.39741026
65NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.39697428
66EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.39187627
67TET1_21451524_ChIP-Seq_MESCs_Mouse1.39045866
68TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38912044
69CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.34902688
70BCOR_27268052_Chip-Seq_Bcells_Human1.34649204
71BCL6_27268052_Chip-Seq_Bcells_Human1.33244310
72ELF1_17652178_ChIP-ChIP_JURKAT_Human1.32849011
73UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.32225224
74RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.31722926
75KDM2B_26808549_Chip-Seq_JURKAT_Human1.31412051
76* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.30382413
77TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.28624548
78IKZF1_21737484_ChIP-ChIP_HCT116_Human1.28471237
79FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.27330272
80ZNF263_19887448_ChIP-Seq_K562_Human1.27133930
81PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.24500850
82PU.1_20513432_ChIP-Seq_Bcells_Mouse1.23373112
83STAT6_21828071_ChIP-Seq_BEAS2B_Human1.23296148
84KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.23126670
85ESR2_21235772_ChIP-Seq_MCF-7_Human1.21826553
86CREB1_26743006_Chip-Seq_LNCaP_Human1.21374841
87* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.20454291
88PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20235076
89GATA1_19941827_ChIP-Seq_MEL_Mouse1.19322474
90CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.17520200
91GATA3_27048872_Chip-Seq_THYMUS_Human1.17385621
92SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17253792
93CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.16552138
94XRN2_22483619_ChIP-Seq_HELA_Human1.16217204
95CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15898097
96ERG_21242973_ChIP-ChIP_JURKAT_Human1.13521519
97KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.13425289
98GATA1_22383799_ChIP-Seq_G1ME_Mouse1.13364429
99LXR_22292898_ChIP-Seq_THP-1_Human1.12479180
100DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11938100
101RUNX1_27514584_Chip-Seq_MCF-7_Human1.11618277
102MYC_19079543_ChIP-ChIP_MESCs_Mouse1.11030416
103NCOR1_26117541_ChIP-Seq_K562_Human1.10981405
104SRY_22984422_ChIP-ChIP_TESTIS_Rat1.10137855
105TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.09693046
106GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08826932
107DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.08335959
108CTCF_26484167_Chip-Seq_Bcells_Mouse1.06713131
109SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.05777616
110KDM5A_27292631_Chip-Seq_BREAST_Human1.05242728
111CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.05198757
112SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.05194087
113ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.05097791
114* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.03778366
115E2F1_21310950_ChIP-Seq_MCF-7_Human1.03715287
116GATA1_19941826_ChIP-Seq_K562_Human1.03439096
117RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.03047360
118P300_27058665_Chip-Seq_ZR-75-30cells_Human1.03014539
119TP53_22127205_ChIP-Seq_IMR90_Human1.01569794
120EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01553616
121ERG_20887958_ChIP-Seq_HPC-7_Mouse1.01433533
122PHF8_20622854_ChIP-Seq_HELA_Human1.01323437
123FOXP3_21729870_ChIP-Seq_TREG_Human1.01046732
124MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.00552258
125* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99070757
126* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.98773494
127HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.97453626
128LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.96962529
129ZFP281_18757296_ChIP-ChIP_E14_Mouse0.96874936
130GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95732441
131KDM2B_26808549_Chip-Seq_K562_Human0.94839845
132* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.91901822
133MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.91294981
134GATA2_22383799_ChIP-Seq_G1ME_Mouse0.91229144
135ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.90200972
136PKCTHETA_26484144_Chip-Seq_BREAST_Human0.89666946
137DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.89322237
138CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88627444
139PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87687164
140STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.87459738
141E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.87105180
142DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.85904380
143* PU_27001747_Chip-Seq_BMDM_Mouse0.82217646
144P68_20966046_ChIP-Seq_HELA_Human0.81687651

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.58006179
2MP0008260_abnormal_autophagy3.09201726
3MP0005451_abnormal_body_composition2.80173382
4MP0008057_abnormal_DNA_replication2.67444827
5MP0001800_abnormal_humoral_immune2.59545198
6MP0001835_abnormal_antigen_presentation2.55427669
7MP0003172_abnormal_lysosome_physiology2.51111069
8MP0002452_abnormal_antigen_presenting2.26921140
9MP0009278_abnormal_bone_marrow2.23637983
10MP0003191_abnormal_cellular_cholesterol2.20278697
11MP0002396_abnormal_hematopoietic_system2.18185412
12MP0005671_abnormal_response_to2.18155926
13MP0001790_abnormal_immune_system2.14887506
14MP0005387_immune_system_phenotype2.14887506
15MP0003724_increased_susceptibility_to2.12788014
16MP0002398_abnormal_bone_marrow2.12686567
17MP0005174_abnormal_tail_pigmentation2.11384065
18MP0002420_abnormal_adaptive_immunity2.08573256
19MP0003705_abnormal_hypodermis_morpholog2.08221296
20MP0005000_abnormal_immune_tolerance2.08148443
21MP0001819_abnormal_immune_cell2.03554053
22MP0003303_peritoneal_inflammation1.98690196
23MP0002723_abnormal_immune_serum1.98009327
24MP0010094_abnormal_chromosome_stability1.96402643
25MP0000685_abnormal_immune_system1.92363339
26MP0003763_abnormal_thymus_physiology1.91099434
27MP0003283_abnormal_digestive_organ1.88761713
28MP0005058_abnormal_lysosome_morphology1.85965108
29MP0008961_abnormal_basal_metabolism1.84815592
30MP0000716_abnormal_immune_system1.83810404
31MP0000689_abnormal_spleen_morphology1.83243242
32MP0001533_abnormal_skeleton_physiology1.82197850
33MP0004858_abnormal_nervous_system1.76076746
34MP0009840_abnormal_foam_cell1.73696628
35MP0003300_gastrointestinal_ulcer1.71875588
36MP0002722_abnormal_immune_system1.68938089
37MP0000703_abnormal_thymus_morphology1.68651690
38MP0000858_altered_metastatic_potential1.67903522
39MP0010155_abnormal_intestine_physiology1.64631926
40MP0003183_abnormal_peptide_metabolism1.62507224
41MP0003111_abnormal_nucleus_morphology1.60194861
42MP0003077_abnormal_cell_cycle1.60116207
43MP0002429_abnormal_blood_cell1.59846676
44MP0002419_abnormal_innate_immunity1.56854301
45MP0002998_abnormal_bone_remodeling1.55195144
46MP0004808_abnormal_hematopoietic_stem1.54189719
47MP0003453_abnormal_keratinocyte_physiol1.53435303
48MP0003828_pulmonary_edema1.52516077
49MP0002405_respiratory_system_inflammati1.50638474
50MP0003122_maternal_imprinting1.50279230
51MP0003075_altered_response_to1.49371905
52MP0003121_genomic_imprinting1.46948087
53MP0003436_decreased_susceptibility_to1.46652873
54MP0005076_abnormal_cell_differentiation1.46130741
55MP0001849_ear_inflammation1.45261067
56MP0008877_abnormal_DNA_methylation1.42433134
57MP0005025_abnormal_response_to1.39757547
58MP0008058_abnormal_DNA_repair1.37128526
59MP0010307_abnormal_tumor_latency1.34227493
60MP0004947_skin_inflammation1.33789293
61MP0009333_abnormal_splenocyte_physiolog1.29323202
62MP0008995_early_reproductive_senescence1.27221019
63MP0000015_abnormal_ear_pigmentation1.26309609
64MP0003890_abnormal_embryonic-extraembry1.25592422
65MP0003787_abnormal_imprinting1.18413978
66MP0004510_myositis1.18136221
67MP0003693_abnormal_embryo_hatching1.17497983
68MP0002653_abnormal_ependyma_morphology1.16176685
69MP0005464_abnormal_platelet_physiology1.15119152
70MP0008469_abnormal_protein_level1.14855564
71MP0001851_eye_inflammation1.14751196
72MP0000350_abnormal_cell_proliferation1.14714364
73MP0005377_hearing/vestibular/ear_phenot1.12897870
74MP0003878_abnormal_ear_physiology1.12897870
75MP0005310_abnormal_salivary_gland1.11374763
76MP0004381_abnormal_hair_follicle1.08615854
77MP0002933_joint_inflammation1.08386789
78MP0005397_hematopoietic_system_phenotyp1.06236249
79MP0001545_abnormal_hematopoietic_system1.06236249
80MP0001730_embryonic_growth_arrest1.05863225
81MP0001293_anophthalmia1.04912563
82MP0000604_amyloidosis1.03872718
83MP0000371_diluted_coat_color1.03787296
84MP0008004_abnormal_stomach_pH1.03371761
85MP0002148_abnormal_hypersensitivity_rea1.02753137
86MP0001853_heart_inflammation1.02675948
87MP0004957_abnormal_blastocyst_morpholog1.02484941
88MP0000465_gastrointestinal_hemorrhage1.01466559
89MP0000678_abnormal_parathyroid_gland1.01316810
90MP0004185_abnormal_adipocyte_glucose1.00663284
91MP0003329_amyloid_beta_deposits1.00606286
92MP0000343_altered_response_to1.00531537
93MP0000003_abnormal_adipose_tissue0.96518654
94MP0009764_decreased_sensitivity_to0.96234328
95MP0001873_stomach_inflammation0.96059084
96MP0002234_abnormal_pharynx_morphology0.95030339
97MP0005390_skeleton_phenotype0.93815916
98MP0005409_darkened_coat_color0.93086726
99MP0003690_abnormal_glial_cell0.92433290
100MP0003866_abnormal_defecation0.87117241
101MP0002095_abnormal_skin_pigmentation0.86938846
102MP0004133_heterotaxia0.85632460
103MP0000313_abnormal_cell_death0.84879112
104MP0005166_decreased_susceptibility_to0.84869296
105MP0006082_CNS_inflammation0.84761554
106MP0008007_abnormal_cellular_replicative0.84562832
107MP0003795_abnormal_bone_structure0.84295396
108MP0002019_abnormal_tumor_incidence0.84214963
109MP0002092_abnormal_eye_morphology0.82246756
110MP0000733_abnormal_muscle_development0.82169411
111MP0002084_abnormal_developmental_patter0.81640814
112MP0001529_abnormal_vocalization0.80718785
113MP0003566_abnormal_cell_adhesion0.79978883
114MP0005621_abnormal_cell_physiology0.78651819
115MP0001845_abnormal_inflammatory_respons0.77435972
116MP0004742_abnormal_vestibular_system0.77238457
117MP0004264_abnormal_extraembryonic_tissu0.77040257
118MP0005666_abnormal_adipose_tissue0.76788032
119MP0002085_abnormal_embryonic_tissue0.76588901
120MP0001663_abnormal_digestive_system0.76575934
121MP0002080_prenatal_lethality0.75748889
122MP0005075_abnormal_melanosome_morpholog0.73885908
123MP0005645_abnormal_hypothalamus_physiol0.73719038
124MP0001958_emphysema0.73130824
125MP0002132_abnormal_respiratory_system0.72937082
126MP0002075_abnormal_coat/hair_pigmentati0.72103147
127MP0003448_altered_tumor_morphology0.71921546
128MP0004197_abnormal_fetal_growth/weight/0.70599436
129MP0003656_abnormal_erythrocyte_physiolo0.70168488
130MP0000383_abnormal_hair_follicle0.69929621
131MP0003279_aneurysm0.69371437
132MP0000490_abnormal_crypts_of0.69075474
133MP0002102_abnormal_ear_morphology0.68839133
134MP0002796_impaired_skin_barrier0.68608391
135MP0000920_abnormal_myelination0.68317007
136MP0008874_decreased_physiological_sensi0.67014107
137MP0001727_abnormal_embryo_implantation0.66537567
138MP0002166_altered_tumor_susceptibility0.65268337
139MP0003091_abnormal_cell_migration0.64901323
140MP0002877_abnormal_melanocyte_morpholog0.64355642
141MP0009785_altered_susceptibility_to0.63413396
142MP0001915_intracranial_hemorrhage0.61873263
143MP0004883_abnormal_blood_vessel0.61457754
144MP0009931_abnormal_skin_appearance0.60736762
145MP0003634_abnormal_glial_cell0.59365374

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)4.06968441
2Recurrent abscess formation (HP:0002722)3.60443698
3Cellulitis (HP:0100658)3.45073757
4IgM deficiency (HP:0002850)3.43825400
5Myositis (HP:0100614)3.37733373
6Nasal polyposis (HP:0100582)3.36265486
7Colitis (HP:0002583)3.20936475
8Recurrent gram-negative bacterial infections (HP:0005420)3.13971081
9Recurrent bronchitis (HP:0002837)3.13728670
10Gastrointestinal inflammation (HP:0004386)3.13652609
11Recurrent bacterial skin infections (HP:0005406)3.13384037
12Recurrent viral infections (HP:0004429)3.09447271
13Abnormality of the nasal mucosa (HP:0000433)3.08819372
14Inflammation of the large intestine (HP:0002037)3.08601519
15Dysostosis multiplex (HP:0000943)3.03997575
16Panhypogammaglobulinemia (HP:0003139)2.97025111
17Gastrointestinal stroma tumor (HP:0100723)2.95280866
18Increased IgE level (HP:0003212)2.90386112
19Abnormal number of incisors (HP:0011064)2.90096531
20Abnormality of the fingertips (HP:0001211)2.85454834
21Chronic otitis media (HP:0000389)2.81623508
22Abnormal delayed hypersensitivity skin test (HP:0002963)2.77386008
23Recurrent fungal infections (HP:0002841)2.72987993
24Increased cerebral lipofuscin (HP:0011813)2.67881069
25Gingivitis (HP:0000230)2.62665972
26Orchitis (HP:0100796)2.59692398
27Emphysema (HP:0002097)2.59528773
28Abnormality of glycolipid metabolism (HP:0010969)2.59364945
29Abnormality of liposaccharide metabolism (HP:0010968)2.59364945
30Abnormality of glycosphingolipid metabolism (HP:0004343)2.59364945
31Amyloidosis (HP:0011034)2.54674397
32Hyperacusis (HP:0010780)2.52170169
33Thyroiditis (HP:0100646)2.46710492
34Lymphopenia (HP:0001888)2.44408336
35Metaphyseal cupping (HP:0003021)2.42317361
36Osteomyelitis (HP:0002754)2.38528708
37Abnormality of cells of the lymphoid lineage (HP:0012140)2.36717145
38Thoracic kyphosis (HP:0002942)2.36635402
39Ependymoma (HP:0002888)2.36450360
40Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.35198819
41Abnormality of polysaccharide metabolism (HP:0011012)2.33482065
42Abnormality of glycosaminoglycan metabolism (HP:0004371)2.33482065
43Abnormality of mucopolysaccharide metabolism (HP:0011020)2.33482065
44Supranuclear gaze palsy (HP:0000605)2.33087012
45Polygenic inheritance (HP:0010982)2.31909323
46Recurrent sinusitis (HP:0011108)2.29735738
47Vacuolated lymphocytes (HP:0001922)2.29034116
48Purpura (HP:0000979)2.27625474
49Mucopolysacchariduria (HP:0008155)2.27343396
50Urinary glycosaminoglycan excretion (HP:0003541)2.27343396
51Meningitis (HP:0001287)2.27255558
52Recurrent cutaneous fungal infections (HP:0011370)2.26679734
53Chronic mucocutaneous candidiasis (HP:0002728)2.26679734
54Obstructive sleep apnea (HP:0002870)2.25440663
55Abnormality of the thoracic spine (HP:0100711)2.23289296
56Broad face (HP:0000283)2.22973069
57Tented upper lip vermilion (HP:0010804)2.21702945
58Urticaria (HP:0001025)2.20994748
59Restrictive lung disease (HP:0002091)2.20692967
60Agnosia (HP:0010524)2.20254801
61Absent frontal sinuses (HP:0002688)2.19777111
62Eczematoid dermatitis (HP:0000976)2.19528956
63Vertebral arch anomaly (HP:0008438)2.18619030
64Mediastinal lymphadenopathy (HP:0100721)2.17431196
65Abnormality of macrophages (HP:0004311)2.17240163
66Heterotopia (HP:0002282)2.16928392
67Thin bony cortex (HP:0002753)2.15244970
68Recurrent skin infections (HP:0001581)2.13879282
69Upper limb amyotrophy (HP:0009129)2.13753694
70Distal upper limb amyotrophy (HP:0007149)2.13753694
71J-shaped sella turcica (HP:0002680)2.13245006
72Flat acetabular roof (HP:0003180)2.12117466
73Verrucae (HP:0200043)2.11854944
74Papilloma (HP:0012740)2.11854944
75Hemorrhage of the eye (HP:0011885)2.11558618
76Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.10281807
77Pustule (HP:0200039)2.07932556
78Optic neuritis (HP:0100653)2.07549340
79Retrobulbar optic neuritis (HP:0100654)2.07549340
80Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.06110417
81Long eyelashes (HP:0000527)2.03277466
82Upper motor neuron abnormality (HP:0002127)2.03156598
83Nuclear cataract (HP:0100018)2.02731841
84Chronic sinusitis (HP:0011109)2.01895317
85Segmental peripheral demyelination/remyelination (HP:0003481)2.01527802
86Prolonged bleeding time (HP:0003010)2.01153330
87Loss of speech (HP:0002371)1.98271861
88Prominent nose (HP:0000448)1.98260876
89T lymphocytopenia (HP:0005403)1.98099705
90Lymphoma (HP:0002665)1.97507502
91Chronic obstructive pulmonary disease (HP:0006510)1.97341966
92Obstructive lung disease (HP:0006536)1.97341966
93Renal duplication (HP:0000075)1.97121083
94Gastrointestinal infarctions (HP:0005244)1.96852305
95Abnormal respiratory motile cilium morphology (HP:0005938)1.96516875
96Abnormal respiratory epithelium morphology (HP:0012253)1.96516875
97Overriding aorta (HP:0002623)1.96363058
98Hand muscle atrophy (HP:0009130)1.95791802
99Increased neuronal autofluorescent lipopigment (HP:0002074)1.95331738
100Increased serum ferritin (HP:0003281)1.94447164
101Bronchitis (HP:0012387)1.92197925
102Recurrent pneumonia (HP:0006532)1.90921538
103Pathologic fracture (HP:0002756)1.90462864
104Elevated erythrocyte sedimentation rate (HP:0003565)1.90147860
105Axonal loss (HP:0003447)1.87507081
106Leukopenia (HP:0001882)1.87431996
107Episodic fever (HP:0001954)1.86937248
108Systemic lupus erythematosus (HP:0002725)1.86666793
109Vasculitis (HP:0002633)1.86242644
110Thrombocytosis (HP:0001894)1.85686586
111Failure to thrive in infancy (HP:0001531)1.84545515
112Absent/shortened dynein arms (HP:0200106)1.84324332
113Dynein arm defect of respiratory motile cilia (HP:0012255)1.84324332
114Vertebral compression fractures (HP:0002953)1.84178451
115Small epiphyses (HP:0010585)1.84008442
116Distal lower limb muscle weakness (HP:0009053)1.81895666
117Petechiae (HP:0000967)1.81756472
118Neuronal loss in central nervous system (HP:0002529)1.80853258
119Hepatosplenomegaly (HP:0001433)1.80384254
120Spontaneous hematomas (HP:0007420)1.80111274
121Abnormal ciliary motility (HP:0012262)1.80045166
122Sepsis (HP:0100806)1.79695414
123Apathy (HP:0000741)1.79540531
124Atelectasis (HP:0100750)1.78803685
125Epistaxis (HP:0000421)1.78276899
126Abnormal respiratory motile cilium physiology (HP:0012261)1.78098611
127Recurrent otitis media (HP:0000403)1.77495222
128Mitral regurgitation (HP:0001653)1.76869313
129Long palpebral fissure (HP:0000637)1.75778763
130Cervical subluxation (HP:0003308)1.75319140
131Abnormality of T cells (HP:0002843)1.74790503
132Hypergammaglobulinemia (HP:0010702)1.74283534
133Personality changes (HP:0000751)1.74268146
134IgG deficiency (HP:0004315)1.74261106
135Recurrent lower respiratory tract infections (HP:0002783)1.74060162
136Premature loss of primary teeth (HP:0006323)1.73577610
137Abnormality of the peritoneum (HP:0002585)1.73476178
138Abnormality of T cell number (HP:0011839)1.73058085
139Diminished motivation (HP:0000745)1.71957737
140B lymphocytopenia (HP:0010976)1.70545448
141Abnormality of B cell number (HP:0010975)1.70545448
142Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.70019242
143Anteriorly placed anus (HP:0001545)1.69005091
144Limited elbow extension (HP:0001377)1.68827134
145Ulnar bowing (HP:0003031)1.67801705
146Severe combined immunodeficiency (HP:0004430)1.67520903
147Disinhibition (HP:0000734)1.67358451
148Poikiloderma (HP:0001029)1.66947187
149Abnormality of the right ventricle (HP:0001707)1.66285280
150Interstitial pulmonary disease (HP:0006530)1.66205700
151Stomatitis (HP:0010280)1.65928945
152Spondylolisthesis (HP:0003302)1.65220938
153Intestinal fistula (HP:0100819)1.64679352
154Trigonocephaly (HP:0000243)1.64603823
155Insomnia (HP:0100785)1.64255196
156Hypoplasia of the capital femoral epiphysis (HP:0003090)1.63740955
157Increased nuchal translucency (HP:0010880)1.63015744
158Volvulus (HP:0002580)1.61615682
159Neoplasm of the oral cavity (HP:0100649)1.61228191
160Cerebral aneurysm (HP:0004944)1.61164138
161Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.60586178
162Degeneration of the lateral corticospinal tracts (HP:0002314)1.60586178

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BRD44.85648557
2MAP4K14.43575171
3PRPF4B3.37940257
4CDK123.29024453
5EEF2K2.81802449
6MAP3K102.76009178
7SMG12.74756048
8SIK12.51807038
9RIPK42.46983132
10BLK2.40340261
11SIK32.35303771
12SIK22.33376236
13PASK2.31231792
14IRAK32.00028345
15CSF1R1.96145621
16CLK11.95507807
17KIT1.84726692
18BTK1.79101894
19NEK21.66134971
20GRK61.66027881
21STK101.65932321
22ICK1.65924758
23NME21.64243996
24ITK1.62278945
25MAP3K131.61519229
26SYK1.59708557
27ERN11.59139048
28MAP3K31.49490589
29RIPK11.44553882
30TAOK21.41231932
31UHMK11.29742170
32ALK1.26749137
33HCK1.26042767
34TRIB31.25998022
35IRAK41.25545389
36ZAP701.20915714
37EPHB11.18234043
38PRKD21.07740767
39LCK1.07522980
40CAMK1G1.07140175
41MAP3K61.06208464
42LRRK21.06139607
43TBK11.03275086
44FES1.03164463
45CDC42BPA1.02727033
46TYK21.01407350
47MAP3K91.00552648
48MAP3K10.98886549
49KSR10.96748935
50PDPK10.96509247
51LYN0.92663068
52KSR20.90828149
53CSK0.89515859
54PAK40.88746076
55MARK20.87562245
56CAMK1D0.86796901
57MAPK120.86768811
58TYRO30.86574794
59MAP3K110.86509542
60TESK20.86270706
61ATR0.83460765
62MARK30.83267029
63MATK0.79517868
64NEK10.79478261
65HIPK20.78579467
66EPHA20.75270310
67FLT30.73649313
68PIM10.72550379
69PDK10.71958167
70BUB10.70959116
71CDC70.69363796
72CAMKK10.69028666
73CHEK10.68386478
74PKN20.68317338
75DYRK30.67980863
76IRAK20.67395206
77DYRK1B0.67380242
78ARAF0.65558569
79MAP3K70.65469972
80MAP3K140.65451220
81MAP2K20.65087177
82CDK70.64563198
83PIM20.64523149
84MTOR0.64494895
85WEE10.64117180
86TLK10.63452538
87TESK10.62735944
88IKBKB0.62288735
89MAPK110.62186502
90TSSK60.61488996
91YES10.61050466
92PTK60.60499055
93CDK90.60254113
94FYN0.58772800
95STK40.58544177
96JAK20.57428753
97CHUK0.57034378
98RPS6KB20.56967129
99RET0.56914329
100IKBKE0.55422420
101FGFR20.55076967
102PRKCH0.54315815
103TEC0.54203395
104PDGFRB0.53930208
105BMX0.53609732
106FGFR30.51992525
107MAP2K30.51361597
108TTN0.51351809
109RPS6KA20.51276031
110PRKD30.50947496
111MAPK70.50666075
112FGR0.49837802
113TGFBR20.49470996
114STK110.47593685
115CDK190.47492022
116PAK20.47475791
117LMTK20.43447838
118TAOK10.42905599
119MOS0.42904866
120TNK20.42406679
121JAK10.42273509
122MELK0.42122937
123BRAF0.42031495
124AKT20.41940937
125STK380.40872838
126PDGFRA0.39171606
127JAK30.38982178
128RPS6KA60.38939319
129CDK20.38869293
130MAP2K60.38839900
131DDR20.38775671
132CSNK1D0.35915437
133RPS6KC10.35815993
134RPS6KL10.35815993
135MAP3K80.35146801
136CDK40.32406589
137MAPK150.32225004
138PAK60.31761274
139MAPK100.31181008
140FGFR40.30778776

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.70725185
2Primary immunodeficiency_Homo sapiens_hsa053402.57107919
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.45389310
4Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.03051119
5DNA replication_Homo sapiens_hsa030301.85627626
6Base excision repair_Homo sapiens_hsa034101.85626766
7Mismatch repair_Homo sapiens_hsa034301.84570127
8Staphylococcus aureus infection_Homo sapiens_hsa051501.79138745
9Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.61544978
10Non-homologous end-joining_Homo sapiens_hsa034501.61245905
11Osteoclast differentiation_Homo sapiens_hsa043801.61041503
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.60488115
13Spliceosome_Homo sapiens_hsa030401.54790477
14Glycosaminoglycan degradation_Homo sapiens_hsa005311.49157139
15Notch signaling pathway_Homo sapiens_hsa043301.48005599
16T cell receptor signaling pathway_Homo sapiens_hsa046601.46619810
17Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.46541408
18Lysosome_Homo sapiens_hsa041421.44175077
19Leishmaniasis_Homo sapiens_hsa051401.42690790
20Allograft rejection_Homo sapiens_hsa053301.40030143
21mRNA surveillance pathway_Homo sapiens_hsa030151.35585891
22Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.34753562
23Chronic myeloid leukemia_Homo sapiens_hsa052201.33977936
24Hematopoietic cell lineage_Homo sapiens_hsa046401.32950913
25Graft-versus-host disease_Homo sapiens_hsa053321.30113210
26Antigen processing and presentation_Homo sapiens_hsa046121.29904828
27Autoimmune thyroid disease_Homo sapiens_hsa053201.27361846
28Epstein-Barr virus infection_Homo sapiens_hsa051691.20382900
29Cell cycle_Homo sapiens_hsa041101.16057266
30Bladder cancer_Homo sapiens_hsa052191.14917670
31Measles_Homo sapiens_hsa051621.13607557
32Homologous recombination_Homo sapiens_hsa034401.13125281
33Neurotrophin signaling pathway_Homo sapiens_hsa047221.13062089
34Malaria_Homo sapiens_hsa051441.12871296
35Other glycan degradation_Homo sapiens_hsa005111.12210599
36Leukocyte transendothelial migration_Homo sapiens_hsa046701.08246980
37Tuberculosis_Homo sapiens_hsa051521.07268774
38Transcriptional misregulation in cancer_Homo sapiens_hsa052021.06647010
39Acute myeloid leukemia_Homo sapiens_hsa052211.04706066
40Non-small cell lung cancer_Homo sapiens_hsa052231.02486252
41Toll-like receptor signaling pathway_Homo sapiens_hsa046201.02129484
42Herpes simplex infection_Homo sapiens_hsa051681.01198338
43Apoptosis_Homo sapiens_hsa042101.00922751
44Chemokine signaling pathway_Homo sapiens_hsa040621.00423823
45Hepatitis B_Homo sapiens_hsa051610.99131376
46Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.96980994
47MicroRNAs in cancer_Homo sapiens_hsa052060.96805300
48Colorectal cancer_Homo sapiens_hsa052100.95269211
49HTLV-I infection_Homo sapiens_hsa051660.94519308
50Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93456932
51Endometrial cancer_Homo sapiens_hsa052130.93357227
52Prion diseases_Homo sapiens_hsa050200.93179258
53RNA transport_Homo sapiens_hsa030130.91977468
54Central carbon metabolism in cancer_Homo sapiens_hsa052300.90919164
55Asthma_Homo sapiens_hsa053100.90633548
56Influenza A_Homo sapiens_hsa051640.90381474
57mTOR signaling pathway_Homo sapiens_hsa041500.89949546
58GnRH signaling pathway_Homo sapiens_hsa049120.88671543
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88380170
60Pancreatic cancer_Homo sapiens_hsa052120.87993319
61Viral myocarditis_Homo sapiens_hsa054160.87668703
62Amoebiasis_Homo sapiens_hsa051460.87564954
63Shigellosis_Homo sapiens_hsa051310.87407007
64Endocytosis_Homo sapiens_hsa041440.86495623
65Prolactin signaling pathway_Homo sapiens_hsa049170.85666817
66Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.85595709
67Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.85414590
68Type I diabetes mellitus_Homo sapiens_hsa049400.84689371
69NOD-like receptor signaling pathway_Homo sapiens_hsa046210.84083872
70VEGF signaling pathway_Homo sapiens_hsa043700.83765737
71Intestinal immune network for IgA production_Homo sapiens_hsa046720.83151904
72Renal cell carcinoma_Homo sapiens_hsa052110.82612033
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.82233769
74Type II diabetes mellitus_Homo sapiens_hsa049300.81621336
75Viral carcinogenesis_Homo sapiens_hsa052030.81528863
76Sphingolipid signaling pathway_Homo sapiens_hsa040710.79527871
77Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77264626
78Adipocytokine signaling pathway_Homo sapiens_hsa049200.76659422
79Rheumatoid arthritis_Homo sapiens_hsa053230.76627118
80Nucleotide excision repair_Homo sapiens_hsa034200.76128080
81Platelet activation_Homo sapiens_hsa046110.75434814
82Toxoplasmosis_Homo sapiens_hsa051450.75100090
83Jak-STAT signaling pathway_Homo sapiens_hsa046300.73723423
84Phospholipase D signaling pathway_Homo sapiens_hsa040720.72453734
85Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72393453
86Pertussis_Homo sapiens_hsa051330.72083348
87Legionellosis_Homo sapiens_hsa051340.71198279
88Fanconi anemia pathway_Homo sapiens_hsa034600.70273580
89African trypanosomiasis_Homo sapiens_hsa051430.69639172
90Insulin resistance_Homo sapiens_hsa049310.68898160
91Glioma_Homo sapiens_hsa052140.68585113
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.67638110
93Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.67119068
94Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.66574730
95Estrogen signaling pathway_Homo sapiens_hsa049150.66447366
96Salmonella infection_Homo sapiens_hsa051320.66087328
97AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65056206
98Dorso-ventral axis formation_Homo sapiens_hsa043200.64462710
99p53 signaling pathway_Homo sapiens_hsa041150.62811956
100Inositol phosphate metabolism_Homo sapiens_hsa005620.62359881
101Galactose metabolism_Homo sapiens_hsa000520.62304306
102Oocyte meiosis_Homo sapiens_hsa041140.62011504
103Lysine degradation_Homo sapiens_hsa003100.61900158
104Insulin signaling pathway_Homo sapiens_hsa049100.61855871
105MAPK signaling pathway_Homo sapiens_hsa040100.60955744
106Small cell lung cancer_Homo sapiens_hsa052220.60884845
107Axon guidance_Homo sapiens_hsa043600.59647705
108Basal cell carcinoma_Homo sapiens_hsa052170.59589657
109Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59205107
110Thyroid cancer_Homo sapiens_hsa052160.57801555
111Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.57472372
112Proteoglycans in cancer_Homo sapiens_hsa052050.57233838
113ErbB signaling pathway_Homo sapiens_hsa040120.56846606
114Phagosome_Homo sapiens_hsa041450.56836097
115Pathways in cancer_Homo sapiens_hsa052000.55814878
116Glycerophospholipid metabolism_Homo sapiens_hsa005640.55608130
117Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54893752
118Fructose and mannose metabolism_Homo sapiens_hsa000510.54777926
119Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53347826
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53193449
121Vibrio cholerae infection_Homo sapiens_hsa051100.52659664
122Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51989061
123Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51927222
124Choline metabolism in cancer_Homo sapiens_hsa052310.50871883
125Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50540643
126RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.50329448
127Prostate cancer_Homo sapiens_hsa052150.49512536
128Pentose phosphate pathway_Homo sapiens_hsa000300.49502099
129Hepatitis C_Homo sapiens_hsa051600.48050782
130HIF-1 signaling pathway_Homo sapiens_hsa040660.44783726
131Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44710655
132TNF signaling pathway_Homo sapiens_hsa046680.44446347

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