STK19B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein neddylation (GO:0045116)6.59524587
2positive regulation of synaptic transmission, dopaminergic (GO:0032226)5.53050632
3thrombin receptor signaling pathway (GO:0070493)5.14247256
4negative regulation of homotypic cell-cell adhesion (GO:0034111)5.11167541
5blood coagulation, intrinsic pathway (GO:0007597)5.03257885
6regulation of platelet aggregation (GO:0090330)5.01133538
7positive regulation of catecholamine secretion (GO:0033605)4.75228280
8mitochondrial calcium ion transport (GO:0006851)4.73703665
9relaxation of smooth muscle (GO:0044557)4.68748282
10negative regulation of platelet activation (GO:0010544)4.58827588
11triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.54884437
12regulation of platelet activation (GO:0010543)4.53507476
13negative regulation of cardiac muscle cell apoptotic process (GO:0010667)4.43623504
14adenosine receptor signaling pathway (GO:0001973)4.34456055
15fusion of sperm to egg plasma membrane (GO:0007342)4.28869171
16deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.28459126
17regulation of integrin-mediated signaling pathway (GO:2001044)4.20622613
18platelet aggregation (GO:0070527)4.09244914
19nucleoside diphosphate biosynthetic process (GO:0009133)4.08667131
20regulation of oxidative phosphorylation (GO:0002082)4.08609021
21negative regulation of heart rate (GO:0010459)4.03864246
22coenzyme catabolic process (GO:0009109)3.96063590
23negative regulation of norepinephrine secretion (GO:0010700)3.94812521
24neutrophil activation involved in immune response (GO:0002283)3.88211772
25ADP metabolic process (GO:0046031)3.84878330
26nucleoside diphosphate phosphorylation (GO:0006165)3.80777461
27response to muscle activity (GO:0014850)3.69155346
28regulation of female receptivity (GO:0045924)3.62755252
29regulation of autophagic vacuole assembly (GO:2000785)3.52607842
30mitochondrial calcium ion homeostasis (GO:0051560)3.52253193
31low-density lipoprotein particle remodeling (GO:0034374)3.44634386
32positive regulation of endothelial cell differentiation (GO:0045603)3.41789150
33response to parathyroid hormone (GO:0071107)3.41532807
34negative regulation of thymocyte apoptotic process (GO:0070244)3.37509932
35regulation of vacuole organization (GO:0044088)3.36036712
36regulation of synaptic transmission, dopaminergic (GO:0032225)3.35982922
37purinergic nucleotide receptor signaling pathway (GO:0035590)3.35487244
38positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.34960843
39cellular response to zinc ion (GO:0071294)3.34476375
40regulation of lipoprotein metabolic process (GO:0050746)3.34438665
41plasma membrane fusion (GO:0045026)3.34249113
42activation of protein kinase B activity (GO:0032148)3.29383547
43arginine catabolic process (GO:0006527)3.23640252
44regulation of dopamine secretion (GO:0014059)3.21210899
45negative regulation of response to food (GO:0032096)3.20571809
46negative regulation of appetite (GO:0032099)3.20571809
47polyamine biosynthetic process (GO:0006596)3.19690681
48calcium ion import (GO:0070509)3.14834429
49negative regulation of macrophage derived foam cell differentiation (GO:0010745)3.12336609
50regulation of homotypic cell-cell adhesion (GO:0034110)3.10523153
51platelet degranulation (GO:0002576)3.09550233
52cytolysis (GO:0019835)3.03847606
53positive regulation of macrophage differentiation (GO:0045651)3.03150777
54leukocyte migration involved in inflammatory response (GO:0002523)3.02018970
55regulation of oxidative stress-induced neuron death (GO:1903203)2.99484684
56cellular response to cadmium ion (GO:0071276)2.98003026
57female mating behavior (GO:0060180)2.97697247
58positive regulation of protein homodimerization activity (GO:0090073)2.96509656
59extracellular fibril organization (GO:0043206)2.96183202
60xenobiotic catabolic process (GO:0042178)2.95790761
61G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.94151261
62positive regulation of protein kinase C signaling (GO:0090037)2.92982133
63regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033392.92742535
64multicellular organism reproduction (GO:0032504)2.91523200
65negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.89361428
66negative regulation of protein localization to cell surface (GO:2000009)2.86131800
67positive regulation of cAMP-mediated signaling (GO:0043950)2.85983048
68negative regulation of striated muscle cell apoptotic process (GO:0010664)2.81901083
69negative regulation of muscle contraction (GO:0045932)2.81356584
70peroxisome fission (GO:0016559)2.79626528
71protein localization to cell surface (GO:0034394)2.78839454
72behavioral response to cocaine (GO:0048148)2.75062497
73purinergic receptor signaling pathway (GO:0035587)2.74869430
74pyrimidine nucleoside catabolic process (GO:0046135)2.74682874
75regulation of catecholamine secretion (GO:0050433)2.72740607
76lipoxygenase pathway (GO:0019372)2.72427137
77relaxation of muscle (GO:0090075)2.71944092
78protein import into peroxisome matrix (GO:0016558)2.71446951
79negative regulation of heart contraction (GO:0045822)2.71295624
80positive regulation of substrate adhesion-dependent cell spreading (GO:1900026)2.70417912
81neuronal action potential propagation (GO:0019227)2.69725756
82behavioral response to nicotine (GO:0035095)2.69555582
83dopamine transport (GO:0015872)2.67385556
84androgen biosynthetic process (GO:0006702)2.66912806
85autophagic vacuole fusion (GO:0000046)2.65379620
86cGMP-mediated signaling (GO:0019934)2.64736797
87nitric oxide mediated signal transduction (GO:0007263)2.64627029
88maternal behavior (GO:0042711)2.64515788
89negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)2.62518405
90positive regulation of Rho protein signal transduction (GO:0035025)2.60093134
91cellular response to toxic substance (GO:0097237)2.60069242
92muscle cell cellular homeostasis (GO:0046716)2.56295990
93negative regulation of muscle cell apoptotic process (GO:0010656)2.55144263
94homotypic cell-cell adhesion (GO:0034109)2.53335455
95peroxisome organization (GO:0007031)2.52475566
96positive regulation of wound healing (GO:0090303)2.52280277
97positive regulation of mast cell activation (GO:0033005)2.52116158
98positive regulation of systemic arterial blood pressure (GO:0003084)2.51027224
99platelet activation (GO:0030168)2.50814682
100regulation of norepinephrine secretion (GO:0014061)2.50774209

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.53684015
2GBX2_23144817_ChIP-Seq_PC3_Human4.78693182
3SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human4.67297265
4EZH2_22144423_ChIP-Seq_EOC_Human4.34581442
5LYL1_20887958_ChIP-Seq_HPC-7_Mouse3.38960679
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.66152307
7IKZF1_21737484_ChIP-ChIP_HCT116_Human2.65678436
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.65149352
9SCL_19346495_ChIP-Seq_HPC-7_Human2.59345431
10VDR_22108803_ChIP-Seq_LS180_Human2.41523619
11GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human2.36407144
12RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.27266159
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.25541982
14CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.14742265
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.13044402
16PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.08949552
17CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.08092272
18HTT_18923047_ChIP-ChIP_STHdh_Human2.07675940
19LMO2_20887958_ChIP-Seq_HPC-7_Mouse2.04295508
20CDX2_19796622_ChIP-Seq_MESCs_Mouse1.90282710
21IGF1R_20145208_ChIP-Seq_DFB_Human1.89474012
22GATA1_19941826_ChIP-Seq_K562_Human1.82868038
23ESR1_20079471_ChIP-ChIP_T-47D_Human1.76021081
24GATA2_19941826_ChIP-Seq_K562_Human1.75665153
25NANOG_20526341_ChIP-Seq_ESCs_Human1.70979264
26ER_23166858_ChIP-Seq_MCF-7_Human1.66145689
27SPI1_23127762_ChIP-Seq_K562_Human1.59009655
28GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.55351453
29GATA1_19941827_ChIP-Seq_MEL_Mouse1.50685114
30EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.47642345
31SPI1_20517297_ChIP-Seq_HL60_Human1.46321945
32PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.46015941
33GATA3_21878914_ChIP-Seq_MCF-7_Human1.34380767
34ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.29622962
35TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.25892874
36PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.23424476
37GATA1_22383799_ChIP-Seq_G1ME_Mouse1.23161161
38ETV2_25802403_ChIP-Seq_MESCs_Mouse1.15836595
39HNFA_21074721_ChIP-Seq_CACO-2_Human1.15823517
40MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.13757536
41EGR1_23403033_ChIP-Seq_LIVER_Mouse1.13687847
42VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.12402257
43NFYB_21822215_ChIP-Seq_K562_Human1.10513509
44SRY_22984422_ChIP-ChIP_TESTIS_Rat1.10191522
45NFYA_21822215_ChIP-Seq_K562_Human1.09694718
46CTCF_20526341_ChIP-Seq_ESCs_Human1.08937906
47TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.08786778
48ELF1_20517297_ChIP-Seq_JURKAT_Human1.07874424
49STAT1_20625510_ChIP-Seq_HELA_Human1.07405334
50PHF8_20622853_ChIP-Seq_HELA_Human1.06566429
51UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05236246
52SMAD4_21799915_ChIP-Seq_A2780_Human1.04950107
53TBL1_22424771_ChIP-Seq_293T_Human1.02933852
54CTCF_21964334_ChIP-Seq_BJAB-B_Human1.02813936
55SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.02607320
56ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02108385
57GATA2_21666600_ChIP-Seq_HMVEC_Human1.01960404
58ELK4_26923725_Chip-Seq_MESODERM_Mouse1.01205988
59SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.99574764
60SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.98986683
61RAD21_21589869_ChIP-Seq_MESCs_Mouse0.98352520
62MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.97755803
63RARG_19884340_ChIP-ChIP_MEFs_Mouse0.96738823
64SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.96663368
65TDRD3_21172665_ChIP-Seq_MCF-7_Human0.95638267
66CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.95067504
67Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.92866413
68STAT1_17558387_ChIP-Seq_HELA_Human0.92302153
69CTCF_21964334_Chip-Seq_Bcells_Human0.90168463
70TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90000925
71RBPJ_21746931_ChIP-Seq_IB4_Human0.89944402
72ERA_21632823_ChIP-Seq_H3396_Human0.89859646
73P300_19829295_ChIP-Seq_ESCs_Human0.87222765
74MTF2_20144788_ChIP-Seq_MESCs_Mouse0.86668868
75GATA6_21074721_ChIP-Seq_CACO-2_Human0.83866338
76YY1_22570637_ChIP-Seq_MALME-3M_Human0.83831919
77OCT1_27270436_Chip-Seq_PROSTATE_Human0.83757411
78NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.83756958
79NRF2_20460467_ChIP-Seq_MEFs_Mouse0.83756958
80EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.83076230
81KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.83019334
82CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.82848680
83PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.82143675
84EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.81150157
85CTCF_27219007_Chip-Seq_Bcells_Human0.80739942
86CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.79924008
87CTBP2_25329375_ChIP-Seq_LNCAP_Human0.79123385
88TAF15_26573619_Chip-Seq_HEK293_Human0.78899016
89MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.78709637
90ETV1_20927104_ChIP-Seq_GIST48_Human0.78101465
91SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.77149842
92POU3F2_20337985_ChIP-ChIP_501MEL_Human0.76905096
93GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.76289294
94CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.75658477
95SALL4_22934838_ChIP-ChIP_CD34+_Human0.74696826
96CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.74426193
97TAF2_19829295_ChIP-Seq_ESCs_Human0.73193187
98HOXB7_26014856_ChIP-Seq_BT474_Human0.72800861
99STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.72465921
100P53_22127205_ChIP-Seq_FIBROBLAST_Human0.72463312

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005464_abnormal_platelet_physiology6.22261039
2MP0008004_abnormal_stomach_pH5.72835063
3MP0004084_abnormal_cardiac_muscle4.17989787
4MP0003806_abnormal_nucleotide_metabolis3.97994199
5MP0009780_abnormal_chondrocyte_physiolo3.22973628
6MP0002132_abnormal_respiratory_system3.11627682
7MP0003879_abnormal_hair_cell3.00810603
8MP0004036_abnormal_muscle_relaxation2.85676708
9MP0002837_dystrophic_cardiac_calcinosis2.80538707
10MP0005083_abnormal_biliary_tract2.71706427
11MP0003123_paternal_imprinting2.53389047
12MP0000749_muscle_degeneration2.37890452
13MP0008775_abnormal_heart_ventricle2.35596181
14MP0009697_abnormal_copulation2.31215819
15MP0000343_altered_response_to2.26804085
16MP0003724_increased_susceptibility_to1.99785001
17MP0000230_abnormal_systemic_arterial1.98320260
18MP0006276_abnormal_autonomic_nervous1.93268277
19MP0002102_abnormal_ear_morphology1.91706000
20MP0000465_gastrointestinal_hemorrhage1.80780055
21MP0005646_abnormal_pituitary_gland1.80296218
22MP0004215_abnormal_myocardial_fiber1.80290092
23MP0005167_abnormal_blood-brain_barrier1.77186228
24MP0003136_yellow_coat_color1.75143767
25MP0002736_abnormal_nociception_after1.72024072
26MP0008872_abnormal_physiological_respon1.71043148
27MP0004272_abnormal_basement_membrane1.68157794
28MP0001849_ear_inflammation1.67995522
29MP0004510_myositis1.67193970
30MP0002160_abnormal_reproductive_system1.57271247
31MP0010368_abnormal_lymphatic_system1.56872376
32MP0010386_abnormal_urinary_bladder1.56514111
33MP0003828_pulmonary_edema1.55251530
34MP0005410_abnormal_fertilization1.47420232
35MP0001485_abnormal_pinna_reflex1.45649872
36MP0005394_taste/olfaction_phenotype1.44194646
37MP0005499_abnormal_olfactory_system1.44194646
38MP0005058_abnormal_lysosome_morphology1.36706417
39MP0001664_abnormal_digestion1.34444112
40MP0006036_abnormal_mitochondrial_physio1.31470943
41MP0002638_abnormal_pupillary_reflex1.31371757
42MP0002733_abnormal_thermal_nociception1.29951047
43MP0003638_abnormal_response/metabolism_1.28718204
44MP0005620_abnormal_muscle_contractility1.27204444
45MP0001968_abnormal_touch/_nociception1.26645286
46MP0004147_increased_porphyrin_level1.24125950
47MP0005385_cardiovascular_system_phenoty1.22615293
48MP0001544_abnormal_cardiovascular_syste1.22615293
49MP0001970_abnormal_pain_threshold1.19752216
50MP0001879_abnormal_lymphatic_vessel1.15850339
51MP0005084_abnormal_gallbladder_morpholo1.11523481
52MP0001756_abnormal_urination1.10123534
53MP0002972_abnormal_cardiac_muscle1.06107959
54MP0004130_abnormal_muscle_cell1.06062267
55MP0005360_urolithiasis1.02437499
56MP0006138_congestive_heart_failure1.00250265
57MP0009840_abnormal_foam_cell0.97782727
58MP0004484_altered_response_of0.96847232
59MP0001661_extended_life_span0.95288928
60MP0004085_abnormal_heartbeat0.93034331
61MP0009765_abnormal_xenobiotic_induced0.90837222
62MP0002127_abnormal_cardiovascular_syste0.89012663
63MP0004142_abnormal_muscle_tone0.88700081
64MP0005409_darkened_coat_color0.87993699
65MP0001905_abnormal_dopamine_level0.79852856
66MP0004145_abnormal_muscle_electrophysio0.78221166
67MP0002272_abnormal_nervous_system0.73362552
68MP0005389_reproductive_system_phenotype0.70264260
69MP0009642_abnormal_blood_homeostasis0.69235044
70MP0003011_delayed_dark_adaptation0.68847654
71MP0003121_genomic_imprinting0.66279539
72MP0001919_abnormal_reproductive_system0.66127193
73MP0001765_abnormal_ion_homeostasis0.65787337
74MP0003122_maternal_imprinting0.65172064
75MP0003656_abnormal_erythrocyte_physiolo0.65043417
76MP0004133_heterotaxia0.64173469
77MP0008875_abnormal_xenobiotic_pharmacok0.62674786
78MP0008874_decreased_physiological_sensi0.62210940
79MP0001663_abnormal_digestive_system0.60460840
80MP0000249_abnormal_blood_vessel0.59638391
81MP0000681_abnormal_thyroid_gland0.57722149
82MP0005187_abnormal_penis_morphology0.57313589
83MP0001835_abnormal_antigen_presentation0.56947566
84MP0005174_abnormal_tail_pigmentation0.55963124
85MP0010329_abnormal_lipoprotein_level0.55531208
86MP0005551_abnormal_eye_electrophysiolog0.54844991
87MP0003938_abnormal_ear_development0.54785604
88MP0006072_abnormal_retinal_apoptosis0.54052132
89MP0009763_increased_sensitivity_to0.52645542
90MP0004885_abnormal_endolymph0.52595051
91MP0005448_abnormal_energy_balance0.52277532
92MP0002233_abnormal_nose_morphology0.51209839
93MP0005330_cardiomyopathy0.51083043
94MP0002138_abnormal_hepatobiliary_system0.50550363
95MP0002118_abnormal_lipid_homeostasis0.49509038
96MP0001529_abnormal_vocalization0.49283834
97MP0008789_abnormal_olfactory_epithelium0.49255301
98MP0005535_abnormal_body_temperature0.48887642
99MP0005381_digestive/alimentary_phenotyp0.48833716
100MP0005253_abnormal_eye_physiology0.48580321

Predicted human phenotypes

RankGene SetZ-score
1Prolonged bleeding time (HP:0003010)8.80458197
2Menorrhagia (HP:0000132)7.98247897
3Petechiae (HP:0000967)7.77268164
4Increased mean platelet volume (HP:0011877)7.30405787
5Purpura (HP:0000979)6.89562077
6Abnormal platelet volume (HP:0011876)6.75791955
7Epistaxis (HP:0000421)5.50171240
8Dyschromatopsia (HP:0007641)5.31102145
9Hyperlipoproteinemia (HP:0010980)4.79955028
10Poikilocytosis (HP:0004447)4.75169320
11Acanthocytosis (HP:0001927)4.63778172
12Impaired platelet aggregation (HP:0003540)4.48313913
13Abnormal platelet function (HP:0011869)4.48313913
14Gingival bleeding (HP:0000225)4.43521606
15Abnormal pupillary function (HP:0007686)3.57904328
16Abnormality of the heme biosynthetic pathway (HP:0010472)3.47867206
17Clumsiness (HP:0002312)3.32208811
18Ventricular fibrillation (HP:0001663)3.28694167
19Decreased activity of mitochondrial respiratory chain (HP:0008972)3.13162149
20Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.13162149
21Hyporeflexia of lower limbs (HP:0002600)3.07656202
22Renal Fanconi syndrome (HP:0001994)3.05257844
23Muscle fiber atrophy (HP:0100295)3.03547710
24Type 2 muscle fiber atrophy (HP:0003554)3.02750455
25Eosinophilia (HP:0001880)2.96687487
26Weak cry (HP:0001612)2.90434568
27Xanthomatosis (HP:0000991)2.73012687
28Easy fatigability (HP:0003388)2.60845237
29Abnormal ciliary motility (HP:0012262)2.60283799
30Spontaneous hematomas (HP:0007420)2.55995057
31Abnormality of the neuromuscular junction (HP:0003398)2.51431517
32Fatigable weakness (HP:0003473)2.51431517
33Acute necrotizing encephalopathy (HP:0006965)2.50418660
34Abnormal hair whorl (HP:0010721)2.50364297
35Resting tremor (HP:0002322)2.50332545
36Abnormality of lateral ventricle (HP:0030047)2.48202367
37Joint hemorrhage (HP:0005261)2.44657192
38Bruising susceptibility (HP:0000978)2.42069233
39Brushfield spots (HP:0001088)2.40977511
40Abnormal respiratory motile cilium morphology (HP:0005938)2.39497619
41Abnormal respiratory epithelium morphology (HP:0012253)2.39497619
42Decreased central vision (HP:0007663)2.37191538
43Upper limb muscle weakness (HP:0003484)2.37110822
44Hyperthyroidism (HP:0000836)2.36529934
45Spinal rigidity (HP:0003306)2.25055016
46Hypophosphatemic rickets (HP:0004912)2.24756066
47Tinnitus (HP:0000360)2.22757137
48Abnormality of the shoulder girdle musculature (HP:0001435)2.22257189
49Abnormal mitochondria in muscle tissue (HP:0008316)2.22020316
50Abnormality of the columella (HP:0009929)2.21839054
51Granulocytopenia (HP:0001913)2.21108979
52Scapular winging (HP:0003691)2.19787381
53Rimmed vacuoles (HP:0003805)2.18579429
54Acute encephalopathy (HP:0006846)2.17049578
55Decreased muscle mass (HP:0003199)2.16187469
56Generalized aminoaciduria (HP:0002909)2.15310842
57Postural instability (HP:0002172)2.14735737
58Exercise-induced myalgia (HP:0003738)2.12626926
59Paralysis (HP:0003470)2.10730775
60Progressive macrocephaly (HP:0004481)2.09849914
61Exertional dyspnea (HP:0002875)2.09317592
62Increased IgM level (HP:0003496)2.04596873
63Lipid accumulation in hepatocytes (HP:0006561)2.02652812
64Atonic seizures (HP:0010819)2.00209748
65Nonprogressive disorder (HP:0003680)1.95895267
66Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.95297886
67Abnormality of the common coagulation pathway (HP:0010990)1.94829845
68Type II lissencephaly (HP:0007260)1.94421961
69Increased variability in muscle fiber diameter (HP:0003557)1.94024761
70Median cleft lip (HP:0000161)1.92632730
71Aortic aneurysm (HP:0004942)1.91966716
72Calf muscle hypertrophy (HP:0008981)1.90308439
73Increased density of long bones (HP:0006392)1.89466704
74Stomatitis (HP:0010280)1.88585330
75Respiratory insufficiency due to muscle weakness (HP:0002747)1.87550238
76Infertility (HP:0000789)1.86773496
77Pachygyria (HP:0001302)1.85886128
78Male infertility (HP:0003251)1.85867500
79Truncus arteriosus (HP:0001660)1.85496049
80Bulbar palsy (HP:0001283)1.84545289
81Spontaneous abortion (HP:0005268)1.81106258
82Mitochondrial inheritance (HP:0001427)1.79018677
83Abnormality of the calf musculature (HP:0001430)1.77513235
84Abnormal EKG (HP:0003115)1.76054327
85Muscle hypertrophy of the lower extremities (HP:0008968)1.73842313
86Abnormality of eosinophils (HP:0001879)1.73495492
87Enlarged kidneys (HP:0000105)1.72571738
88Abnormality of renal resorption (HP:0011038)1.72239968
89Absent/shortened dynein arms (HP:0200106)1.71687795
90Dynein arm defect of respiratory motile cilia (HP:0012255)1.71687795
91Failure to thrive in infancy (HP:0001531)1.69676110
92Retinal dysplasia (HP:0007973)1.67627886
93Joint swelling (HP:0001386)1.66807744
94Abnormality of skeletal muscle fiber size (HP:0012084)1.66593682
95Abnormal respiratory motile cilium physiology (HP:0012261)1.65063702
96Exercise-induced muscle cramps (HP:0003710)1.64729318
97Difficulty walking (HP:0002355)1.63707811
98Increased muscle lipid content (HP:0009058)1.62422183
99Polyphagia (HP:0002591)1.62246312
100Urinary urgency (HP:0000012)1.60673082

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PINK16.60542664
2MYLK4.79200764
3MARK33.38932309
4RIPK43.23373432
5OBSCN3.02303403
6MUSK2.72260559
7BMX2.64776307
8MST42.14023428
9ADRBK22.13243286
10BTK2.05539797
11BMPR1B2.04327091
12NEK21.88303317
13TRIM281.88157178
14PTK2B1.73433987
15EIF2AK11.63276896
16GRK51.60698417
17LATS11.50675219
18ILK1.50211436
19DAPK31.42782102
20TEC1.36440187
21MAP2K71.36200240
22STK31.35941403
23PAK31.31118629
24PAK11.24953663
25GRK61.22591314
26CDK81.16716815
27GRK11.15493787
28DYRK31.12152192
29ARAF1.12075651
30CCNB11.09852407
31TLK11.06168326
32NME21.05012645
33MINK11.02833827
34CDC71.02655801
35TNK21.01256786
36STK38L1.00128263
37MAPK120.99378109
38PIK3CG0.97812573
39SYK0.92362357
40FGR0.90421311
41TIE10.89823800
42TAOK30.89817949
43MAP3K40.83534984
44SGK20.83151130
45MAP3K50.81675799
46SGK2230.80913002
47SGK4940.80913002
48PRKG20.79255559
49MAPKAPK30.79007075
50TNIK0.77394382
51WNK40.77095748
52ADRBK10.74756636
53ZAK0.71018733
54PKN10.70389896
55CSF1R0.70056576
56PHKG20.69188547
57PHKG10.69188547
58MAP3K10.67286049
59RET0.67129207
60MAPK130.66611708
61CDK30.64240844
62ROCK10.63049973
63TGFBR10.62686933
64BCR0.62168619
65CDC42BPA0.60767253
66CAMK10.59092978
67PDPK10.58479812
68SIK20.57102190
69HCK0.56599743
70CSNK1G30.55649876
71SGK30.55601052
72PAK20.55439405
73DYRK20.53963526
74PRKCQ0.53302364
75CDK140.51100326
76CAMKK20.51074328
77PDK10.50483109
78ZAP700.48765282
79MOS0.48759532
80AKT20.48741570
81SIK30.48556368
82PRKG10.47433568
83PRKACG0.43530100
84CAMKK10.41488851
85STK40.40826208
86CSNK1G20.40740635
87IKBKB0.40395585
88FRK0.39782181
89FES0.39658721
90PNCK0.39538923
91CSNK1A1L0.39049417
92IRAK20.38296945
93PLK20.37469792
94LYN0.37160293
95LATS20.35753888
96PRKACA0.34299468
97ACVR1B0.33128242
98PRKD10.33077572
99LMTK20.32698938
100PRKCB0.32050424

Predicted pathways (KEGG)

RankGene SetZ-score
1Platelet activation_Homo sapiens_hsa046114.10052116
2SNARE interactions in vesicular transport_Homo sapiens_hsa041303.11431254
3Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.76536389
4Nitrogen metabolism_Homo sapiens_hsa009102.76430830
5Olfactory transduction_Homo sapiens_hsa047402.48473530
6Vascular smooth muscle contraction_Homo sapiens_hsa042702.33665387
7Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.32275256
8Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.18110913
9ECM-receptor interaction_Homo sapiens_hsa045122.04811483
10Arachidonic acid metabolism_Homo sapiens_hsa005901.97906149
11Gap junction_Homo sapiens_hsa045401.94825257
12Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.94177519
13Chemical carcinogenesis_Homo sapiens_hsa052041.86695393
14Dilated cardiomyopathy_Homo sapiens_hsa054141.83166742
15Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.82264630
16Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.70965645
17Steroid hormone biosynthesis_Homo sapiens_hsa001401.68544207
18Parkinsons disease_Homo sapiens_hsa050121.67787745
19Collecting duct acid secretion_Homo sapiens_hsa049661.59451972
20Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.56827042
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.56442295
22alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.55802285
23Serotonergic synapse_Homo sapiens_hsa047261.51569151
24Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.49033867
25Circadian entrainment_Homo sapiens_hsa047131.46542004
26Oxytocin signaling pathway_Homo sapiens_hsa049211.45753315
27Regulation of autophagy_Homo sapiens_hsa041401.42262365
28Oxidative phosphorylation_Homo sapiens_hsa001901.42012266
29GABAergic synapse_Homo sapiens_hsa047271.38323072
30Linoleic acid metabolism_Homo sapiens_hsa005911.33589532
31Steroid biosynthesis_Homo sapiens_hsa001001.27972791
32Calcium signaling pathway_Homo sapiens_hsa040201.22988968
33Glutathione metabolism_Homo sapiens_hsa004801.22062069
34Cardiac muscle contraction_Homo sapiens_hsa042601.18810974
35beta-Alanine metabolism_Homo sapiens_hsa004101.16785009
36Renin secretion_Homo sapiens_hsa049241.14095071
37Hematopoietic cell lineage_Homo sapiens_hsa046401.13728180
38Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.12135032
39cGMP-PKG signaling pathway_Homo sapiens_hsa040221.09399410
40Sphingolipid metabolism_Homo sapiens_hsa006001.07618897
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.05439512
42Starch and sucrose metabolism_Homo sapiens_hsa005001.04136462
43Mineral absorption_Homo sapiens_hsa049781.03477817
44Morphine addiction_Homo sapiens_hsa050321.03083576
45Chemokine signaling pathway_Homo sapiens_hsa040621.01287110
46Glycerolipid metabolism_Homo sapiens_hsa005611.00432628
47Retinol metabolism_Homo sapiens_hsa008301.00318859
48Ovarian steroidogenesis_Homo sapiens_hsa049130.91017920
49Pancreatic secretion_Homo sapiens_hsa049720.88637398
50Alcoholism_Homo sapiens_hsa050340.86862273
51Alzheimers disease_Homo sapiens_hsa050100.85430552
52Pentose and glucuronate interconversions_Homo sapiens_hsa000400.85207763
53Phototransduction_Homo sapiens_hsa047440.83181879
54Gastric acid secretion_Homo sapiens_hsa049710.82581507
55Arginine biosynthesis_Homo sapiens_hsa002200.80754625
56Purine metabolism_Homo sapiens_hsa002300.80208704
57Cholinergic synapse_Homo sapiens_hsa047250.73195633
58Synaptic vesicle cycle_Homo sapiens_hsa047210.72772907
59Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70691465
60Glycosaminoglycan degradation_Homo sapiens_hsa005310.70002493
61Focal adhesion_Homo sapiens_hsa045100.69672064
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69284854
63Tyrosine metabolism_Homo sapiens_hsa003500.69044346
64Systemic lupus erythematosus_Homo sapiens_hsa053220.68531438
65Salivary secretion_Homo sapiens_hsa049700.66161983
66Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65709028
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.64692591
68Peroxisome_Homo sapiens_hsa041460.63816998
69Long-term depression_Homo sapiens_hsa047300.63542931
70Sulfur metabolism_Homo sapiens_hsa009200.61988060
71Glutamatergic synapse_Homo sapiens_hsa047240.61833935
72Fat digestion and absorption_Homo sapiens_hsa049750.60749893
73Complement and coagulation cascades_Homo sapiens_hsa046100.58228074
74Endocytosis_Homo sapiens_hsa041440.57560707
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.56448242
76Melanoma_Homo sapiens_hsa052180.56345283
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54920725
78PPAR signaling pathway_Homo sapiens_hsa033200.53371517
79Phagosome_Homo sapiens_hsa041450.52582680
80Drug metabolism - other enzymes_Homo sapiens_hsa009830.51761353
81Choline metabolism in cancer_Homo sapiens_hsa052310.48287462
82Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.47969600
83Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47732422
84Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.47128820
85Pyrimidine metabolism_Homo sapiens_hsa002400.44689758
86Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.43145342
87Butanoate metabolism_Homo sapiens_hsa006500.41855339
88Bile secretion_Homo sapiens_hsa049760.39848440
89Shigellosis_Homo sapiens_hsa051310.38780857
90Metabolic pathways_Homo sapiens_hsa011000.37642421
91Ras signaling pathway_Homo sapiens_hsa040140.36413897
92Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.35369153
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.35261501
94Phospholipase D signaling pathway_Homo sapiens_hsa040720.34781962
95Malaria_Homo sapiens_hsa051440.34643313
96Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.34594731
97Arginine and proline metabolism_Homo sapiens_hsa003300.34094709
98Insulin secretion_Homo sapiens_hsa049110.33823912
99Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.32008176
100Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.30281348

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »