

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Golgi transport vesicle coating (GO:0048200) | 8.16531757 |
| 2 | COPI coating of Golgi vesicle (GO:0048205) | 8.16531757 |
| 3 | melanin biosynthetic process (GO:0042438) | 6.25178914 |
| 4 | secondary metabolite biosynthetic process (GO:0044550) | 5.59403617 |
| 5 | melanin metabolic process (GO:0006582) | 5.47876125 |
| 6 | endocrine pancreas development (GO:0031018) | 5.37399122 |
| 7 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.36327559 |
| 8 | postsynaptic membrane organization (GO:0001941) | 5.21353396 |
| 9 | protein maturation by protein folding (GO:0022417) | 5.20526333 |
| 10 | response to pheromone (GO:0019236) | 5.17628407 |
| 11 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 5.07434748 |
| 12 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.96921803 |
| 13 | peptide hormone processing (GO:0016486) | 4.93205681 |
| 14 | ER overload response (GO:0006983) | 4.86738865 |
| 15 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 4.83015009 |
| 16 | insulin secretion (GO:0030073) | 4.72480026 |
| 17 | presynaptic membrane assembly (GO:0097105) | 4.71053220 |
| 18 | type B pancreatic cell development (GO:0003323) | 4.66995406 |
| 19 | COPII vesicle coating (GO:0048208) | 4.62279096 |
| 20 | glandular epithelial cell development (GO:0002068) | 4.53355832 |
| 21 | nucleobase catabolic process (GO:0046113) | 4.49341932 |
| 22 | presynaptic membrane organization (GO:0097090) | 4.37457109 |
| 23 | detection of calcium ion (GO:0005513) | 4.35374216 |
| 24 | glandular epithelial cell differentiation (GO:0002067) | 4.27038062 |
| 25 | axonal fasciculation (GO:0007413) | 4.23103541 |
| 26 | protein retention in ER lumen (GO:0006621) | 4.22581645 |
| 27 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 4.10146529 |
| 28 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 4.10075776 |
| 29 | positive regulation of insulin secretion (GO:0032024) | 4.01573971 |
| 30 | regulation of insulin secretion (GO:0050796) | 4.00113474 |
| 31 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.93370528 |
| 32 | vesicle coating (GO:0006901) | 3.92142168 |
| 33 | signal peptide processing (GO:0006465) | 3.86753227 |
| 34 | positive regulation of nuclease activity (GO:0032075) | 3.84329244 |
| 35 | exocrine pancreas development (GO:0031017) | 3.82521518 |
| 36 | negative regulation of norepinephrine secretion (GO:0010700) | 3.81715763 |
| 37 | auditory behavior (GO:0031223) | 3.79249995 |
| 38 | regulation of glucocorticoid secretion (GO:2000849) | 3.76546004 |
| 39 | neuron cell-cell adhesion (GO:0007158) | 3.76238736 |
| 40 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.75616479 |
| 41 | nonmotile primary cilium assembly (GO:0035058) | 3.71964273 |
| 42 | negative regulation of catecholamine secretion (GO:0033604) | 3.67518975 |
| 43 | retinal ganglion cell axon guidance (GO:0031290) | 3.65886441 |
| 44 | regulation of peptide hormone secretion (GO:0090276) | 3.65463381 |
| 45 | neuron recognition (GO:0008038) | 3.61290041 |
| 46 | regulation of peptide secretion (GO:0002791) | 3.59131154 |
| 47 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.54544823 |
| 48 | ganglion development (GO:0061548) | 3.49323571 |
| 49 | neuronal action potential propagation (GO:0019227) | 3.49181177 |
| 50 | sequestering of metal ion (GO:0051238) | 3.47704316 |
| 51 | regulation of nuclease activity (GO:0032069) | 3.46172710 |
| 52 | peptide hormone secretion (GO:0030072) | 3.46013086 |
| 53 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 3.42332395 |
| 54 | peptide secretion (GO:0002790) | 3.40758002 |
| 55 | columnar/cuboidal epithelial cell development (GO:0002066) | 3.40357950 |
| 56 | chemosensory behavior (GO:0007635) | 3.40051660 |
| 57 | endoplasmic reticulum unfolded protein response (GO:0030968) | 3.39813219 |
| 58 | intra-Golgi vesicle-mediated transport (GO:0006891) | 3.37372299 |
| 59 | cellular response to unfolded protein (GO:0034620) | 3.36982472 |
| 60 | axon extension involved in axon guidance (GO:0048846) | 3.34101666 |
| 61 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.34101666 |
| 62 | tyrosine metabolic process (GO:0006570) | 3.32667279 |
| 63 | positive regulation of peptide hormone secretion (GO:0090277) | 3.32129471 |
| 64 | nitric oxide mediated signal transduction (GO:0007263) | 3.30281997 |
| 65 | ER-nucleus signaling pathway (GO:0006984) | 3.28180708 |
| 66 | cellular response to topologically incorrect protein (GO:0035967) | 3.28159946 |
| 67 | negative regulation of axon guidance (GO:1902668) | 3.28052510 |
| 68 | mechanosensory behavior (GO:0007638) | 3.26001808 |
| 69 | cellular response to glucagon stimulus (GO:0071377) | 3.25914436 |
| 70 | regulation of hormone secretion (GO:0046883) | 3.25291574 |
| 71 | regulation of cilium movement (GO:0003352) | 3.24885995 |
| 72 | positive regulation of peptide secretion (GO:0002793) | 3.22672231 |
| 73 | dendritic spine morphogenesis (GO:0060997) | 3.11545639 |
| 74 | synapse assembly (GO:0007416) | 3.10576777 |
| 75 | regulation of norepinephrine secretion (GO:0014061) | 3.10224019 |
| 76 | regulation of corticosteroid hormone secretion (GO:2000846) | 3.08955245 |
| 77 | melanosome transport (GO:0032402) | 3.08273683 |
| 78 | phenol-containing compound catabolic process (GO:0019336) | 3.07793645 |
| 79 | establishment of melanosome localization (GO:0032401) | 3.06024541 |
| 80 | cerebellar Purkinje cell layer development (GO:0021680) | 3.05872051 |
| 81 | developmental pigmentation (GO:0048066) | 3.05131902 |
| 82 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 3.04523706 |
| 83 | regulation of axon extension involved in axon guidance (GO:0048841) | 3.04263258 |
| 84 | toxin metabolic process (GO:0009404) | 3.02317769 |
| 85 | protein localization to synapse (GO:0035418) | 3.01666403 |
| 86 | negative regulation of insulin secretion (GO:0046676) | 3.00273752 |
| 87 | ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) | 2.99945808 |
| 88 | regulation of axon guidance (GO:1902667) | 2.99502055 |
| 89 | macroautophagy (GO:0016236) | 2.99318962 |
| 90 | phenol-containing compound biosynthetic process (GO:0046189) | 2.98514130 |
| 91 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.97412004 |
| 92 | retinal cone cell development (GO:0046549) | 2.96388933 |
| 93 | pigment granule transport (GO:0051904) | 2.94750911 |
| 94 | melanosome localization (GO:0032400) | 2.93268247 |
| 95 | establishment of pigment granule localization (GO:0051905) | 2.93187504 |
| 96 | negative regulation of glycogen biosynthetic process (GO:0045719) | 2.92886111 |
| 97 | regulation of peptide transport (GO:0090087) | 2.90740890 |
| 98 | pigment cell differentiation (GO:0050931) | 2.90521302 |
| 99 | astrocyte differentiation (GO:0048708) | 2.89412555 |
| 100 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.88433497 |
| 101 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.88202943 |
| 102 | regulation of beta-amyloid formation (GO:1902003) | 2.83370315 |
| 103 | dendrite morphogenesis (GO:0048813) | 2.82768514 |
| 104 | inner ear receptor cell development (GO:0060119) | 2.82533416 |
| 105 | pigment granule localization (GO:0051875) | 2.81968425 |
| 106 | behavioral response to nicotine (GO:0035095) | 2.81687587 |
| 107 | ER to Golgi vesicle-mediated transport (GO:0006888) | 2.80289513 |
| 108 | response to endoplasmic reticulum stress (GO:0034976) | 2.80025914 |
| 109 | transmission of nerve impulse (GO:0019226) | 2.79805120 |
| 110 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.79011465 |
| 111 | positive regulation of hormone secretion (GO:0046887) | 2.78537490 |
| 112 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.78429647 |
| 113 | gamma-aminobutyric acid transport (GO:0015812) | 2.74784270 |
| 114 | platelet dense granule organization (GO:0060155) | 2.74740214 |
| 115 | limb development (GO:0060173) | 2.74629424 |
| 116 | appendage development (GO:0048736) | 2.74629424 |
| 117 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.73699578 |
| 118 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.73666068 |
| 119 | melanocyte differentiation (GO:0030318) | 2.73305406 |
| 120 | intraciliary transport (GO:0042073) | 2.73086839 |
| 121 | negative regulation of axon extension (GO:0030517) | 2.70359364 |
| 122 | hormone secretion (GO:0046879) | 2.70335273 |
| 123 | neuroepithelial cell differentiation (GO:0060563) | 2.69073565 |
| 124 | cellular response to vitamin D (GO:0071305) | 2.68978154 |
| 125 | regulation of protein glycosylation (GO:0060049) | 2.68186441 |
| 126 | activation of protein kinase A activity (GO:0034199) | 2.67838774 |
| 127 | spinal cord development (GO:0021510) | 2.67590176 |
| 128 | peptide transport (GO:0015833) | 2.67250799 |
| 129 | striatum development (GO:0021756) | 2.66959262 |
| 130 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 2.66805262 |
| 131 | positive regulation of exocytosis (GO:0045921) | 2.66805004 |
| 132 | short-term memory (GO:0007614) | 2.66769201 |
| 133 | glutamate receptor signaling pathway (GO:0007215) | 2.66591036 |
| 134 | regulation of synapse structural plasticity (GO:0051823) | 2.66132081 |
| 135 | neuronal ion channel clustering (GO:0045161) | 2.65999116 |
| 136 | negative regulation of peptide hormone secretion (GO:0090278) | 2.65887201 |
| 137 | behavioral response to ethanol (GO:0048149) | 2.65350167 |
| 138 | vocalization behavior (GO:0071625) | 2.64890930 |
| 139 | membrane repolarization during action potential (GO:0086011) | 2.64592267 |
| 140 | response to unfolded protein (GO:0006986) | 2.64270688 |
| 141 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.63830314 |
| 142 | protein targeting to Golgi (GO:0000042) | 2.62966381 |
| 143 | synaptic vesicle maturation (GO:0016188) | 2.61908013 |
| 144 | regulation of amyloid precursor protein catabolic process (GO:1902991) | 2.59950973 |
| 145 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.59032232 |
| 146 | exploration behavior (GO:0035640) | 2.58362362 |
| 147 | photoreceptor cell maintenance (GO:0045494) | 2.58291066 |
| 148 | protein localization to Golgi apparatus (GO:0034067) | 2.58225558 |
| 149 | synaptic transmission, glutamatergic (GO:0035249) | 2.57865216 |
| 150 | regulation of microtubule-based movement (GO:0060632) | 2.57446016 |
| 151 | protein N-linked glycosylation via asparagine (GO:0018279) | 2.57406502 |
| 152 | response to topologically incorrect protein (GO:0035966) | 2.56622581 |
| 153 | positive regulation of synapse assembly (GO:0051965) | 2.56514737 |
| 154 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.56487318 |
| 155 | ketone body metabolic process (GO:1902224) | 2.56270428 |
| 156 | response to auditory stimulus (GO:0010996) | 2.55986953 |
| 157 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.55656144 |
| 158 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.55280144 |
| 159 | dopamine metabolic process (GO:0042417) | 2.55248044 |
| 160 | peptidyl-asparagine modification (GO:0018196) | 2.55006206 |
| 161 | hormone transport (GO:0009914) | 2.54627125 |
| 162 | negative regulation of peptide secretion (GO:0002792) | 2.54549211 |
| 163 | negative regulation of response to food (GO:0032096) | 2.54333941 |
| 164 | negative regulation of appetite (GO:0032099) | 2.54333941 |
| 165 | regulation of synaptic vesicle transport (GO:1902803) | 2.54279533 |
| 166 | brain morphogenesis (GO:0048854) | 2.54138525 |
| 167 | regulation of neurotransmitter uptake (GO:0051580) | 2.54125442 |
| 168 | positive regulation of neuroblast proliferation (GO:0002052) | 2.53430183 |
| 169 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.53269202 |
| 170 | locomotory exploration behavior (GO:0035641) | 2.53146840 |
| 171 | interleukin-1-mediated signaling pathway (GO:0070498) | 2.52146971 |
| 172 | catecholamine biosynthetic process (GO:0042423) | 2.51887430 |
| 173 | catechol-containing compound biosynthetic process (GO:0009713) | 2.51887430 |
| 174 | regulation of hexokinase activity (GO:1903299) | 2.51030883 |
| 175 | regulation of glucokinase activity (GO:0033131) | 2.51030883 |
| 176 | epithelial cell fate commitment (GO:0072148) | 2.50934056 |
| 177 | pancreas development (GO:0031016) | 2.50780722 |
| 178 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.50571211 |
| 179 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.47232875 |
| 180 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.42730397 |
| 181 | endosome to pigment granule transport (GO:0043485) | 2.42663783 |
| 182 | endosome to melanosome transport (GO:0035646) | 2.42663783 |
| 183 | regulation of respiratory system process (GO:0044065) | 2.42413254 |
| 184 | cellular response to leptin stimulus (GO:0044320) | 2.41694171 |
| 185 | establishment of nucleus localization (GO:0040023) | 2.41572838 |
| 186 | cilium morphogenesis (GO:0060271) | 2.41059886 |
| 187 | peripheral nervous system development (GO:0007422) | 2.40576078 |
| 188 | C4-dicarboxylate transport (GO:0015740) | 2.40047873 |
| 189 | synapse organization (GO:0050808) | 2.40027062 |
| 190 | atrial cardiac muscle cell action potential (GO:0086014) | 2.39099217 |
| 191 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.35722279 |
| 192 | negative chemotaxis (GO:0050919) | 2.33579172 |
| 193 | neuromuscular synaptic transmission (GO:0007274) | 2.33550574 |
| 194 | pigmentation (GO:0043473) | 2.32609260 |
| 195 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.32463781 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.54419904 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.40905727 |
| 3 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.78907512 |
| 4 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.48090118 |
| 5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.35189907 |
| 6 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.13457460 |
| 7 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.09983793 |
| 8 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.04144694 |
| 9 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.02207170 |
| 10 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.96885229 |
| 11 | GATA1_22025678_ChIP-Seq_K562_Human | 1.94690429 |
| 12 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.93901109 |
| 13 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.93324609 |
| 14 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.93190802 |
| 15 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.89512145 |
| 16 | FUS_26573619_Chip-Seq_HEK293_Human | 1.87376294 |
| 17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.82771745 |
| 18 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.81736837 |
| 19 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.78034872 |
| 20 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.69939714 |
| 21 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.67539669 |
| 22 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.67521671 |
| 23 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.66191256 |
| 24 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.65690078 |
| 25 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.64684448 |
| 26 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.62497658 |
| 27 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.61318300 |
| 28 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.59771643 |
| 29 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.59705311 |
| 30 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.58097992 |
| 31 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.56974636 |
| 32 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.56055509 |
| 33 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.55576570 |
| 34 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.55442088 |
| 35 | VDR_22108803_ChIP-Seq_LS180_Human | 1.54522277 |
| 36 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.53881803 |
| 37 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.52329066 |
| 38 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.51816364 |
| 39 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.51565284 |
| 40 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.51157680 |
| 41 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.49782854 |
| 42 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.47998867 |
| 43 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.46585204 |
| 44 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.46143070 |
| 45 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.45628225 |
| 46 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.43924319 |
| 47 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.38915482 |
| 48 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.38303203 |
| 49 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.38303203 |
| 50 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.37494396 |
| 51 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.37374565 |
| 52 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.36292006 |
| 53 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.34916556 |
| 54 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.33148865 |
| 55 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.32126697 |
| 56 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.30291123 |
| 57 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.29737765 |
| 58 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.29737765 |
| 59 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.29625418 |
| 60 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.28851746 |
| 61 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.27223718 |
| 62 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.24934551 |
| 63 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.23451518 |
| 64 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.23136840 |
| 65 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.23136840 |
| 66 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.23083244 |
| 67 | TCF4_23295773_ChIP-Seq_U87_Human | 1.22099213 |
| 68 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.21365739 |
| 69 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.21162876 |
| 70 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 1.19413850 |
| 71 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.19228076 |
| 72 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.18989228 |
| 73 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.18563115 |
| 74 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.18521262 |
| 75 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.16854538 |
| 76 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.16117029 |
| 77 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.16107552 |
| 78 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.15913637 |
| 79 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.15786118 |
| 80 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.15774611 |
| 81 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15432333 |
| 82 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15140387 |
| 83 | EWS_26573619_Chip-Seq_HEK293_Human | 1.14836126 |
| 84 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.14694022 |
| 85 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.14011940 |
| 86 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.13836103 |
| 87 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.13316949 |
| 88 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.12998627 |
| 89 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.11112217 |
| 90 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.10539106 |
| 91 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.10063540 |
| 92 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.10006917 |
| 93 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.09928839 |
| 94 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.09022836 |
| 95 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.08307158 |
| 96 | AR_19668381_ChIP-Seq_PC3_Human | 1.07704909 |
| 97 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.07552847 |
| 98 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.06868516 |
| 99 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.06034660 |
| 100 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.05045568 |
| 101 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.05044907 |
| 102 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.04855822 |
| 103 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.04780355 |
| 104 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.04648156 |
| 105 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.04335531 |
| 106 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.04152546 |
| 107 | * JUN_21703547_ChIP-Seq_K562_Human | 1.02999129 |
| 108 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.02902347 |
| 109 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02877389 |
| 110 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.02105638 |
| 111 | AR_25329375_ChIP-Seq_VCAP_Human | 0.98043417 |
| 112 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.96584735 |
| 113 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.96095428 |
| 114 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.96033472 |
| 115 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.95879377 |
| 116 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95373391 |
| 117 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.94642131 |
| 118 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.93909434 |
| 119 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.93313491 |
| 120 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.90856072 |
| 121 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.90590970 |
| 122 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.90286294 |
| 123 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.89744008 |
| 124 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.89388207 |
| 125 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.89176801 |
| 126 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.89162521 |
| 127 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.88884573 |
| 128 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.88724073 |
| 129 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.88701249 |
| 130 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.87424052 |
| 131 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.87302214 |
| 132 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.86925500 |
| 133 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.86609135 |
| 134 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85950412 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005171_absent_coat_pigmentation | 5.10808787 |
| 2 | MP0002877_abnormal_melanocyte_morpholog | 4.27553360 |
| 3 | MP0003136_yellow_coat_color | 4.09515226 |
| 4 | MP0000372_irregular_coat_pigmentation | 3.94460465 |
| 5 | MP0002909_abnormal_adrenal_gland | 3.80824420 |
| 6 | MP0003283_abnormal_digestive_organ | 3.78738719 |
| 7 | MP0000013_abnormal_adipose_tissue | 3.65732716 |
| 8 | MP0010386_abnormal_urinary_bladder | 3.59840806 |
| 9 | MP0004043_abnormal_pH_regulation | 3.44551654 |
| 10 | MP0002693_abnormal_pancreas_physiology | 3.41216886 |
| 11 | MP0009780_abnormal_chondrocyte_physiolo | 3.39050083 |
| 12 | MP0003880_abnormal_central_pattern | 3.38531829 |
| 13 | MP0005379_endocrine/exocrine_gland_phen | 3.21207585 |
| 14 | MP0003183_abnormal_peptide_metabolism | 3.13780230 |
| 15 | MP0001944_abnormal_pancreas_morphology | 3.00084753 |
| 16 | MP0005646_abnormal_pituitary_gland | 2.94046499 |
| 17 | MP0002638_abnormal_pupillary_reflex | 2.84047120 |
| 18 | MP0000678_abnormal_parathyroid_gland | 2.76294280 |
| 19 | MP0003195_calcinosis | 2.75087230 |
| 20 | MP0000569_abnormal_digit_pigmentation | 2.67153173 |
| 21 | MP0005408_hypopigmentation | 2.65841167 |
| 22 | MP0001986_abnormal_taste_sensitivity | 2.53439706 |
| 23 | MP0002095_abnormal_skin_pigmentation | 2.48961301 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 2.47305405 |
| 25 | MP0004270_analgesia | 2.46417915 |
| 26 | MP0005174_abnormal_tail_pigmentation | 2.40773499 |
| 27 | MP0000015_abnormal_ear_pigmentation | 2.36124112 |
| 28 | MP0006072_abnormal_retinal_apoptosis | 2.30773671 |
| 29 | MP0002837_dystrophic_cardiac_calcinosis | 2.13901866 |
| 30 | MP0003122_maternal_imprinting | 2.11155182 |
| 31 | MP0002822_catalepsy | 2.08614027 |
| 32 | MP0005075_abnormal_melanosome_morpholog | 2.05515029 |
| 33 | MP0009046_muscle_twitch | 1.94442991 |
| 34 | MP0000003_abnormal_adipose_tissue | 1.93038029 |
| 35 | MP0002078_abnormal_glucose_homeostasis | 1.86445365 |
| 36 | MP0005220_abnormal_exocrine_pancreas | 1.76423187 |
| 37 | MP0000778_abnormal_nervous_system | 1.74006056 |
| 38 | MP0002938_white_spotting | 1.73591876 |
| 39 | MP0002734_abnormal_mechanical_nocicepti | 1.71945917 |
| 40 | MP0001968_abnormal_touch/_nociception | 1.68058474 |
| 41 | MP0000371_diluted_coat_color | 1.65546924 |
| 42 | MP0002735_abnormal_chemical_nociception | 1.59738813 |
| 43 | MP0001502_abnormal_circadian_rhythm | 1.56457556 |
| 44 | MP0004264_abnormal_extraembryonic_tissu | 1.52493415 |
| 45 | MP0003635_abnormal_synaptic_transmissio | 1.51313638 |
| 46 | MP0004381_abnormal_hair_follicle | 1.50590557 |
| 47 | MP0002163_abnormal_gland_morphology | 1.50006752 |
| 48 | MP0001984_abnormal_olfaction | 1.46479027 |
| 49 | MP0001324_abnormal_eye_pigmentation | 1.44053500 |
| 50 | MP0000631_abnormal_neuroendocrine_gland | 1.41469569 |
| 51 | MP0006276_abnormal_autonomic_nervous | 1.40277264 |
| 52 | MP0002736_abnormal_nociception_after | 1.32997746 |
| 53 | MP0003953_abnormal_hormone_level | 1.32981113 |
| 54 | MP0004859_abnormal_synaptic_plasticity | 1.32109110 |
| 55 | MP0005253_abnormal_eye_physiology | 1.26151131 |
| 56 | MP0004858_abnormal_nervous_system | 1.25354247 |
| 57 | MP0002272_abnormal_nervous_system | 1.24901517 |
| 58 | MP0006292_abnormal_olfactory_placode | 1.22194387 |
| 59 | MP0004742_abnormal_vestibular_system | 1.21513897 |
| 60 | MP0000613_abnormal_salivary_gland | 1.21484539 |
| 61 | MP0002572_abnormal_emotion/affect_behav | 1.21441872 |
| 62 | MP0002896_abnormal_bone_mineralization | 1.21050755 |
| 63 | MP0002234_abnormal_pharynx_morphology | 1.20480217 |
| 64 | MP0002063_abnormal_learning/memory/cond | 1.19536599 |
| 65 | MP0002090_abnormal_vision | 1.19352750 |
| 66 | MP0002733_abnormal_thermal_nociception | 1.18964360 |
| 67 | MP0001765_abnormal_ion_homeostasis | 1.18319754 |
| 68 | MP0005248_abnormal_Harderian_gland | 1.17777728 |
| 69 | MP0002557_abnormal_social/conspecific_i | 1.16325722 |
| 70 | MP0009745_abnormal_behavioral_response | 1.12784799 |
| 71 | MP0001970_abnormal_pain_threshold | 1.12688631 |
| 72 | MP0000462_abnormal_digestive_system | 1.12495577 |
| 73 | MP0002075_abnormal_coat/hair_pigmentati | 1.11949023 |
| 74 | MP0005423_abnormal_somatic_nervous | 1.11611146 |
| 75 | MP0008961_abnormal_basal_metabolism | 1.09012177 |
| 76 | MP0004142_abnormal_muscle_tone | 1.08634382 |
| 77 | MP0003787_abnormal_imprinting | 1.07105601 |
| 78 | MP0002653_abnormal_ependyma_morphology | 1.06157511 |
| 79 | MP0003300_gastrointestinal_ulcer | 1.05448843 |
| 80 | MP0003172_abnormal_lysosome_physiology | 1.04746081 |
| 81 | MP0005535_abnormal_body_temperature | 1.04333413 |
| 82 | MP0003011_delayed_dark_adaptation | 1.02275821 |
| 83 | MP0002928_abnormal_bile_duct | 1.02199909 |
| 84 | MP0001756_abnormal_urination | 1.00114123 |
| 85 | MP0001299_abnormal_eye_distance/ | 0.99998530 |
| 86 | MP0001501_abnormal_sleep_pattern | 0.98942220 |
| 87 | MP0002752_abnormal_somatic_nervous | 0.98708746 |
| 88 | MP0003123_paternal_imprinting | 0.97337282 |
| 89 | MP0002184_abnormal_innervation | 0.97058864 |
| 90 | MP0003868_abnormal_feces_composition | 0.96785155 |
| 91 | MP0002876_abnormal_thyroid_physiology | 0.96329087 |
| 92 | MP0003121_genomic_imprinting | 0.95814648 |
| 93 | MP0000955_abnormal_spinal_cord | 0.95022704 |
| 94 | MP0005195_abnormal_posterior_eye | 0.94557673 |
| 95 | MP0005551_abnormal_eye_electrophysiolog | 0.94538999 |
| 96 | MP0005187_abnormal_penis_morphology | 0.92642203 |
| 97 | MP0004145_abnormal_muscle_electrophysio | 0.92494719 |
| 98 | MP0001905_abnormal_dopamine_level | 0.91739111 |
| 99 | MP0002751_abnormal_autonomic_nervous | 0.91096153 |
| 100 | MP0001485_abnormal_pinna_reflex | 0.90946638 |
| 101 | MP0005310_abnormal_salivary_gland | 0.90563318 |
| 102 | MP0001186_pigmentation_phenotype | 0.89046769 |
| 103 | MP0002102_abnormal_ear_morphology | 0.88177930 |
| 104 | MP0003045_fibrosis | 0.88088670 |
| 105 | MP0001270_distended_abdomen | 0.86892469 |
| 106 | MP0004085_abnormal_heartbeat | 0.86601736 |
| 107 | MP0000427_abnormal_hair_cycle | 0.85879297 |
| 108 | MP0005499_abnormal_olfactory_system | 0.85563024 |
| 109 | MP0005394_taste/olfaction_phenotype | 0.85563024 |
| 110 | MP0002064_seizures | 0.85040934 |
| 111 | MP0003879_abnormal_hair_cell | 0.84398457 |
| 112 | MP0000647_abnormal_sebaceous_gland | 0.84070489 |
| 113 | MP0002069_abnormal_eating/drinking_beha | 0.83997639 |
| 114 | MP0008877_abnormal_DNA_methylation | 0.83566920 |
| 115 | MP0001963_abnormal_hearing_physiology | 0.83256929 |
| 116 | MP0000026_abnormal_inner_ear | 0.83183830 |
| 117 | MP0000639_abnormal_adrenal_gland | 0.82710027 |
| 118 | MP0001529_abnormal_vocalization | 0.80682376 |
| 119 | MP0000230_abnormal_systemic_arterial | 0.80342775 |
| 120 | MP0002067_abnormal_sensory_capabilities | 0.80262098 |
| 121 | MP0003959_abnormal_lean_body | 0.80230899 |
| 122 | MP0002152_abnormal_brain_morphology | 0.78955666 |
| 123 | MP0003633_abnormal_nervous_system | 0.78678317 |
| 124 | MP0003632_abnormal_nervous_system | 0.78667272 |
| 125 | MP0005257_abnormal_intraocular_pressure | 0.78544316 |
| 126 | MP0001188_hyperpigmentation | 0.77834458 |
| 127 | MP0008569_lethality_at_weaning | 0.76109519 |
| 128 | MP0004811_abnormal_neuron_physiology | 0.73159717 |
| 129 | MP0002066_abnormal_motor_capabilities/c | 0.73010477 |
| 130 | MP0000538_abnormal_urinary_bladder | 0.72491304 |
| 131 | MP0008789_abnormal_olfactory_epithelium | 0.72063736 |
| 132 | MP0004924_abnormal_behavior | 0.72043522 |
| 133 | MP0005386_behavior/neurological_phenoty | 0.72043522 |
| 134 | MP0002229_neurodegeneration | 0.71935898 |
| 135 | MP0003385_abnormal_body_wall | 0.69606764 |
| 136 | MP0005448_abnormal_energy_balance | 0.69041937 |
| 137 | MP0003890_abnormal_embryonic-extraembry | 0.68821444 |
| 138 | MP0001486_abnormal_startle_reflex | 0.68630322 |
| 139 | MP0000579_abnormal_nail_morphology | 0.68566875 |
| 140 | MP0002882_abnormal_neuron_morphology | 0.68048483 |
| 141 | MP0003119_abnormal_digestive_system | 0.66632273 |
| 142 | MP0001440_abnormal_grooming_behavior | 0.66561638 |
| 143 | MP0005375_adipose_tissue_phenotype | 0.66178941 |
| 144 | MP0000681_abnormal_thyroid_gland | 0.64887485 |
| 145 | MP0004885_abnormal_endolymph | 0.62190616 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hyperinsulinemic hypoglycemia (HP:0000825) | 6.71083073 |
| 2 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 6.41955485 |
| 3 | Hypoglycemic seizures (HP:0002173) | 6.41399635 |
| 4 | Symptomatic seizures (HP:0011145) | 5.87215418 |
| 5 | Hyperglycemia (HP:0003074) | 4.79615004 |
| 6 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 4.72118298 |
| 7 | Insulin-resistant diabetes mellitus (HP:0000831) | 4.69116864 |
| 8 | Hypoglycemic coma (HP:0001325) | 4.68366588 |
| 9 | Blue irides (HP:0000635) | 4.50001270 |
| 10 | White forelock (HP:0002211) | 4.42766440 |
| 11 | Patchy hypopigmentation of hair (HP:0011365) | 4.19983804 |
| 12 | Decreased circulating renin level (HP:0003351) | 4.13477160 |
| 13 | Hypothermia (HP:0002045) | 4.12205660 |
| 14 | Abnormal pancreas size (HP:0012094) | 3.92932668 |
| 15 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.90878371 |
| 16 | Ketoacidosis (HP:0001993) | 3.72260273 |
| 17 | Abnormality of the pancreatic islet cells (HP:0006476) | 3.69515766 |
| 18 | Abnormality of endocrine pancreas physiology (HP:0012093) | 3.69515766 |
| 19 | Large for gestational age (HP:0001520) | 3.66744043 |
| 20 | Congenital sensorineural hearing impairment (HP:0008527) | 3.49209942 |
| 21 | Agitation (HP:0000713) | 3.44264534 |
| 22 | Hypokalemia (HP:0002900) | 3.44074615 |
| 23 | Osteomalacia (HP:0002749) | 3.39798043 |
| 24 | Late onset (HP:0003584) | 3.13173767 |
| 25 | Hemiparesis (HP:0001269) | 3.09255993 |
| 26 | Pheochromocytoma (HP:0002666) | 3.09072427 |
| 27 | Generalized hypopigmentation (HP:0007513) | 3.07388276 |
| 28 | Progressive cerebellar ataxia (HP:0002073) | 2.98674065 |
| 29 | Nephronophthisis (HP:0000090) | 2.94599450 |
| 30 | Myokymia (HP:0002411) | 2.93989556 |
| 31 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.90725198 |
| 32 | Action tremor (HP:0002345) | 2.88018327 |
| 33 | Thyroid-stimulating hormone excess (HP:0002925) | 2.86108786 |
| 34 | Abnormality of renin-angiotensin system (HP:0000847) | 2.85798551 |
| 35 | Polyphagia (HP:0002591) | 2.79300974 |
| 36 | Retinal atrophy (HP:0001105) | 2.78848659 |
| 37 | Abnormality of potassium homeostasis (HP:0011042) | 2.74238079 |
| 38 | Congenital stationary night blindness (HP:0007642) | 2.73419844 |
| 39 | Ocular albinism (HP:0001107) | 2.71422089 |
| 40 | EEG with generalized epileptiform discharges (HP:0011198) | 2.71222849 |
| 41 | Iris hypopigmentation (HP:0007730) | 2.70571866 |
| 42 | Abnormality of the fovea (HP:0000493) | 2.67585373 |
| 43 | Hyperventilation (HP:0002883) | 2.67477032 |
| 44 | Mucopolysacchariduria (HP:0008155) | 2.67308852 |
| 45 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.67308852 |
| 46 | Hypoplasia of the fovea (HP:0007750) | 2.66755801 |
| 47 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.66755801 |
| 48 | Pancreatic cysts (HP:0001737) | 2.66725493 |
| 49 | Hypsarrhythmia (HP:0002521) | 2.65817998 |
| 50 | Neuroendocrine neoplasm (HP:0100634) | 2.65134148 |
| 51 | Abnormality of midbrain morphology (HP:0002418) | 2.65122305 |
| 52 | Molar tooth sign on MRI (HP:0002419) | 2.65122305 |
| 53 | Heterochromia iridis (HP:0001100) | 2.61691442 |
| 54 | Epileptiform EEG discharges (HP:0011182) | 2.61593958 |
| 55 | Papilledema (HP:0001085) | 2.61169008 |
| 56 | Hyperparathyroidism (HP:0000843) | 2.60787128 |
| 57 | Broad-based gait (HP:0002136) | 2.59019734 |
| 58 | Dysostosis multiplex (HP:0000943) | 2.58455912 |
| 59 | Absent speech (HP:0001344) | 2.55563341 |
| 60 | Albinism (HP:0001022) | 2.54831482 |
| 61 | Generalized hypopigmentation of hair (HP:0011358) | 2.54408190 |
| 62 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.51859743 |
| 63 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.51859743 |
| 64 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.51859743 |
| 65 | Prominent metopic ridge (HP:0005487) | 2.51300452 |
| 66 | Abnormality of the renal medulla (HP:0100957) | 2.49504206 |
| 67 | Poor coordination (HP:0002370) | 2.43145003 |
| 68 | Hyperphosphatemia (HP:0002905) | 2.42460067 |
| 69 | Conjugated hyperbilirubinemia (HP:0002908) | 2.42205376 |
| 70 | Chronic bronchitis (HP:0004469) | 2.42122411 |
| 71 | Limb dystonia (HP:0002451) | 2.39884615 |
| 72 | Unilateral renal agenesis (HP:0000122) | 2.35052140 |
| 73 | Hyperkalemia (HP:0002153) | 2.33604843 |
| 74 | Visual hallucinations (HP:0002367) | 2.33579730 |
| 75 | Hyperactive renin-angiotensin system (HP:0000841) | 2.33370648 |
| 76 | Abolished electroretinogram (ERG) (HP:0000550) | 2.29775908 |
| 77 | Gaze-evoked nystagmus (HP:0000640) | 2.28980734 |
| 78 | Abnormality of the metopic suture (HP:0005556) | 2.28477745 |
| 79 | Insulin resistance (HP:0000855) | 2.28010463 |
| 80 | Febrile seizures (HP:0002373) | 2.26849590 |
| 81 | Retinal dysplasia (HP:0007973) | 2.22491015 |
| 82 | Dysautonomia (HP:0002459) | 2.21904861 |
| 83 | Generalized aminoaciduria (HP:0002909) | 2.21869440 |
| 84 | Limb hypertonia (HP:0002509) | 2.20616083 |
| 85 | Amblyopia (HP:0000646) | 2.20305473 |
| 86 | Papillary thyroid carcinoma (HP:0002895) | 2.19452932 |
| 87 | Gait imbalance (HP:0002141) | 2.19342988 |
| 88 | Increased circulating renin level (HP:0000848) | 2.19014541 |
| 89 | Cerebral hypomyelination (HP:0006808) | 2.17574079 |
| 90 | Abnormality of the corticospinal tract (HP:0002492) | 2.17014255 |
| 91 | Congenital primary aphakia (HP:0007707) | 2.16516068 |
| 92 | Specific learning disability (HP:0001328) | 2.15379650 |
| 93 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.13905419 |
| 94 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.13905419 |
| 95 | Medial flaring of the eyebrow (HP:0010747) | 2.12200111 |
| 96 | Menstrual irregularities (HP:0000858) | 2.11943139 |
| 97 | Ulnar claw (HP:0001178) | 2.11794813 |
| 98 | Failure to thrive in infancy (HP:0001531) | 2.11232447 |
| 99 | Hypopigmentation of the fundus (HP:0007894) | 2.10465889 |
| 100 | Abnormality of the renal cortex (HP:0011035) | 2.07911610 |
| 101 | Drooling (HP:0002307) | 2.07356849 |
| 102 | Cystic liver disease (HP:0006706) | 2.05183843 |
| 103 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.04485417 |
| 104 | Prolonged QT interval (HP:0001657) | 2.03652419 |
| 105 | Nephrogenic diabetes insipidus (HP:0009806) | 1.99959059 |
| 106 | Abnormality of the intrinsic pathway (HP:0010989) | 1.99121557 |
| 107 | Aqueductal stenosis (HP:0002410) | 1.98690718 |
| 108 | Absent eyebrow (HP:0002223) | 1.96739899 |
| 109 | Genital tract atresia (HP:0001827) | 1.95495762 |
| 110 | Pancreatic fibrosis (HP:0100732) | 1.95476720 |
| 111 | Hypotension (HP:0002615) | 1.95172755 |
| 112 | Hyperaldosteronism (HP:0000859) | 1.95122895 |
| 113 | Congenital glaucoma (HP:0001087) | 1.94014310 |
| 114 | Focal seizures (HP:0007359) | 1.93890969 |
| 115 | Vaginal atresia (HP:0000148) | 1.92993609 |
| 116 | Focal motor seizures (HP:0011153) | 1.92786906 |
| 117 | Type II diabetes mellitus (HP:0005978) | 1.92114212 |
| 118 | Adrenal overactivity (HP:0002717) | 1.90684751 |
| 119 | Abnormal eating behavior (HP:0100738) | 1.87422561 |
| 120 | Genetic anticipation (HP:0003743) | 1.87222533 |
| 121 | Lissencephaly (HP:0001339) | 1.87035781 |
| 122 | Broad foot (HP:0001769) | 1.86527308 |
| 123 | Hypercortisolism (HP:0001578) | 1.86246606 |
| 124 | Hyperglycinemia (HP:0002154) | 1.84697461 |
| 125 | Atonic seizures (HP:0010819) | 1.83739230 |
| 126 | Disproportionate short-trunk short stature (HP:0003521) | 1.82450615 |
| 127 | Insidious onset (HP:0003587) | 1.82170704 |
| 128 | Termporal pattern (HP:0011008) | 1.82170704 |
| 129 | Split foot (HP:0001839) | 1.81339746 |
| 130 | Excessive salivation (HP:0003781) | 1.81169600 |
| 131 | Hypokalemic alkalosis (HP:0001949) | 1.79874337 |
| 132 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.78862357 |
| 133 | Anxiety (HP:0000739) | 1.77240295 |
| 134 | Optic nerve hypoplasia (HP:0000609) | 1.76787898 |
| 135 | Renal hypoplasia (HP:0000089) | 1.76258121 |
| 136 | Abnormality of chloride homeostasis (HP:0011422) | 1.76216580 |
| 137 | Postural tremor (HP:0002174) | 1.75968263 |
| 138 | Restlessness (HP:0000711) | 1.75958489 |
| 139 | Cortical visual impairment (HP:0100704) | 1.75232464 |
| 140 | Pendular nystagmus (HP:0012043) | 1.75154983 |
| 141 | Postaxial hand polydactyly (HP:0001162) | 1.74503045 |
| 142 | Gastrointestinal atresia (HP:0002589) | 1.74395141 |
| 143 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.74211617 |
| 144 | Neurofibrillary tangles (HP:0002185) | 1.74146080 |
| 145 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.74123442 |
| 146 | Attenuation of retinal blood vessels (HP:0007843) | 1.72918605 |
| 147 | Bifid tongue (HP:0010297) | 1.71407210 |
| 148 | Progressive neurologic deterioration (HP:0002344) | 1.71279436 |
| 149 | CNS hypomyelination (HP:0003429) | 1.70957485 |
| 150 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.70834285 |
| 151 | Abnormal drinking behavior (HP:0030082) | 1.70695163 |
| 152 | Polydipsia (HP:0001959) | 1.70695163 |
| 153 | Glucose intolerance (HP:0000833) | 1.70355419 |
| 154 | Chronic hepatic failure (HP:0100626) | 1.70206562 |
| 155 | Widely spaced teeth (HP:0000687) | 1.70158305 |
| 156 | Pachygyria (HP:0001302) | 1.69988058 |
| 157 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.69306757 |
| 158 | Acute necrotizing encephalopathy (HP:0006965) | 1.69190306 |
| 159 | Orthostatic hypotension (HP:0001278) | 1.68899564 |
| 160 | True hermaphroditism (HP:0010459) | 1.68620614 |
| 161 | Intestinal atresia (HP:0011100) | 1.68221553 |
| 162 | Absence seizures (HP:0002121) | 1.67554312 |
| 163 | Adrenal hypoplasia (HP:0000835) | 1.67348336 |
| 164 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.67028286 |
| 165 | Progressive macrocephaly (HP:0004481) | 1.66739705 |
| 166 | Abnormal EKG (HP:0003115) | 1.65916600 |
| 167 | Thyroid carcinoma (HP:0002890) | 1.65813518 |
| 168 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.65801892 |
| 169 | Macroorchidism (HP:0000053) | 1.65068921 |
| 170 | Aganglionic megacolon (HP:0002251) | 1.65068452 |
| 171 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.64528466 |
| 172 | Resting tremor (HP:0002322) | 1.63623229 |
| 173 | Type II lissencephaly (HP:0007260) | 1.63533737 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | INSRR | 6.90358401 |
| 2 | PASK | 3.95352748 |
| 3 | TAOK3 | 3.52341079 |
| 4 | MAPK15 | 3.40251739 |
| 5 | BMPR1B | 3.18770457 |
| 6 | PRKD3 | 2.98038922 |
| 7 | HIPK2 | 2.84955782 |
| 8 | NTRK3 | 2.81357038 |
| 9 | MAP3K2 | 2.78150597 |
| 10 | NTRK1 | 2.54774462 |
| 11 | FRK | 2.53237392 |
| 12 | WNK3 | 2.18402645 |
| 13 | PDK2 | 2.14884003 |
| 14 | CAMKK2 | 2.08788127 |
| 15 | AKT3 | 2.02072251 |
| 16 | PHKG2 | 1.98915419 |
| 17 | PHKG1 | 1.98915419 |
| 18 | WNK4 | 1.96108251 |
| 19 | FGFR2 | 1.91667997 |
| 20 | UHMK1 | 1.81637190 |
| 21 | DYRK2 | 1.70843099 |
| 22 | CDC42BPA | 1.53843610 |
| 23 | MAP3K1 | 1.46377185 |
| 24 | MAP4K2 | 1.44710497 |
| 25 | CSNK1G3 | 1.41715564 |
| 26 | GRK1 | 1.39311413 |
| 27 | PDGFRA | 1.37037050 |
| 28 | DDR2 | 1.35297383 |
| 29 | ADRBK2 | 1.34168879 |
| 30 | CSNK1G1 | 1.33787617 |
| 31 | EPHA3 | 1.33147684 |
| 32 | CSNK1A1L | 1.32479346 |
| 33 | FLT3 | 1.30991609 |
| 34 | MAP2K7 | 1.29763171 |
| 35 | SCYL2 | 1.27618591 |
| 36 | SGK2 | 1.24390591 |
| 37 | SGK223 | 1.23258457 |
| 38 | SGK494 | 1.23258457 |
| 39 | BRAF | 1.23109055 |
| 40 | PRKCH | 1.23104245 |
| 41 | MAP3K4 | 1.22337459 |
| 42 | IRAK1 | 1.22097283 |
| 43 | WNK1 | 1.14877381 |
| 44 | MKNK2 | 1.13754198 |
| 45 | TYRO3 | 1.12389392 |
| 46 | MARK1 | 1.11148962 |
| 47 | STK38L | 1.09970183 |
| 48 | MAPK13 | 1.08376109 |
| 49 | ARAF | 1.03632464 |
| 50 | LMTK2 | 1.03135169 |
| 51 | STK39 | 1.00993298 |
| 52 | RPS6KA2 | 0.96606183 |
| 53 | PKN1 | 0.95321088 |
| 54 | PTK2 | 0.93604747 |
| 55 | MST1R | 0.92805685 |
| 56 | IRAK3 | 0.92338830 |
| 57 | OXSR1 | 0.91712845 |
| 58 | PAK3 | 0.89483534 |
| 59 | BMPR2 | 0.88512384 |
| 60 | CAMKK1 | 0.87653368 |
| 61 | ACVR1B | 0.87618762 |
| 62 | RET | 0.85929355 |
| 63 | TGFBR1 | 0.84667920 |
| 64 | PRKCE | 0.82887118 |
| 65 | ERBB2 | 0.82573501 |
| 66 | SGK3 | 0.82475179 |
| 67 | CASK | 0.81719779 |
| 68 | PLK2 | 0.81515280 |
| 69 | CDK19 | 0.80883223 |
| 70 | WEE1 | 0.78742192 |
| 71 | NEK6 | 0.77390593 |
| 72 | CAMK2D | 0.76535635 |
| 73 | PRKD2 | 0.75606457 |
| 74 | EPHB2 | 0.75066563 |
| 75 | KSR2 | 0.73624011 |
| 76 | MUSK | 0.73297176 |
| 77 | MAPKAPK3 | 0.72903705 |
| 78 | PIK3CG | 0.72001488 |
| 79 | MAP3K9 | 0.70345909 |
| 80 | SIK2 | 0.70180343 |
| 81 | PTK2B | 0.70046324 |
| 82 | PRKCZ | 0.69854349 |
| 83 | IRAK2 | 0.69846405 |
| 84 | PRKAA1 | 0.69021675 |
| 85 | PNCK | 0.67602456 |
| 86 | FER | 0.67584089 |
| 87 | MINK1 | 0.66576224 |
| 88 | CDK5 | 0.65660673 |
| 89 | TRIM28 | 0.60669212 |
| 90 | BCKDK | 0.60412276 |
| 91 | MAPKAPK5 | 0.59323124 |
| 92 | CSNK1D | 0.57363403 |
| 93 | ERN1 | 0.57113713 |
| 94 | NTRK2 | 0.56498610 |
| 95 | DAPK2 | 0.55939377 |
| 96 | CAMK2B | 0.54437033 |
| 97 | MARK2 | 0.52968505 |
| 98 | NUAK1 | 0.51906288 |
| 99 | CAMK1 | 0.51317249 |
| 100 | SIK3 | 0.49856199 |
| 101 | PRKCI | 0.49795106 |
| 102 | STK38 | 0.49585840 |
| 103 | MET | 0.49196979 |
| 104 | RPS6KB1 | 0.48874125 |
| 105 | PRKCG | 0.48501014 |
| 106 | ERBB3 | 0.48358939 |
| 107 | GRK5 | 0.48258843 |
| 108 | PRKACB | 0.47716032 |
| 109 | DYRK1B | 0.46642244 |
| 110 | PDGFRB | 0.44416359 |
| 111 | CSNK1A1 | 0.44318711 |
| 112 | STK11 | 0.43530559 |
| 113 | CAMK1G | 0.43509055 |
| 114 | ADRBK1 | 0.42356783 |
| 115 | PRKACA | 0.41836376 |
| 116 | MAP2K4 | 0.41635907 |
| 117 | CAMK2A | 0.40402332 |
| 118 | GSK3A | 0.39363393 |
| 119 | PAK6 | 0.39151520 |
| 120 | PRKACG | 0.39011702 |
| 121 | SGK1 | 0.38892375 |
| 122 | FGFR1 | 0.37134797 |
| 123 | ALK | 0.36881241 |
| 124 | MAP2K1 | 0.36761711 |
| 125 | CSNK1E | 0.36408575 |
| 126 | EPHB1 | 0.36102777 |
| 127 | BCR | 0.35709073 |
| 128 | PINK1 | 0.35487494 |
| 129 | EIF2AK3 | 0.35005680 |
| 130 | PRPF4B | 0.34363707 |
| 131 | PRKD1 | 0.34260075 |
| 132 | CDK18 | 0.33946882 |
| 133 | BRSK1 | 0.33943844 |
| 134 | TNIK | 0.33019204 |
| 135 | PIM2 | 0.32953304 |
| 136 | MAP2K2 | 0.32192538 |
| 137 | ERBB4 | 0.29901588 |
| 138 | RPS6KA3 | 0.29855880 |
| 139 | NLK | 0.29081149 |
| 140 | DYRK1A | 0.28064943 |
| 141 | MAPK10 | 0.27757544 |
| 142 | PTK6 | 0.26738743 |
| 143 | EPHA4 | 0.25952010 |
| 144 | CSNK1G2 | 0.25341308 |
| 145 | GRK7 | 0.25082627 |
| 146 | KSR1 | 0.24820841 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 7.18870399 |
| 2 | Protein export_Homo sapiens_hsa03060 | 4.15340981 |
| 3 | Insulin secretion_Homo sapiens_hsa04911 | 3.37099637 |
| 4 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.49252467 |
| 5 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.40802473 |
| 6 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 2.35424855 |
| 7 | Cocaine addiction_Homo sapiens_hsa05030 | 2.26404132 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.20818085 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.12020409 |
| 10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.03796023 |
| 11 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.00615572 |
| 12 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.93408276 |
| 13 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.90432831 |
| 14 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.82489487 |
| 15 | Taste transduction_Homo sapiens_hsa04742 | 1.77551534 |
| 16 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.72505998 |
| 17 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.65520590 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.61452740 |
| 19 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.60874849 |
| 20 | GABAergic synapse_Homo sapiens_hsa04727 | 1.60414520 |
| 21 | Circadian entrainment_Homo sapiens_hsa04713 | 1.59704144 |
| 22 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.58937347 |
| 23 | Parkinsons disease_Homo sapiens_hsa05012 | 1.58589966 |
| 24 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.50222974 |
| 25 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.50003955 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.49140141 |
| 27 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.48075204 |
| 28 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.46082639 |
| 29 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.45350277 |
| 30 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.44043249 |
| 31 | Olfactory transduction_Homo sapiens_hsa04740 | 1.41935373 |
| 32 | Long-term potentiation_Homo sapiens_hsa04720 | 1.41539008 |
| 33 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.37580184 |
| 34 | Morphine addiction_Homo sapiens_hsa05032 | 1.36410080 |
| 35 | Axon guidance_Homo sapiens_hsa04360 | 1.33906093 |
| 36 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.29289939 |
| 37 | Circadian rhythm_Homo sapiens_hsa04710 | 1.26868937 |
| 38 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.26184655 |
| 39 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.24648421 |
| 40 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.24044558 |
| 41 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.22599322 |
| 42 | Alzheimers disease_Homo sapiens_hsa05010 | 1.18524861 |
| 43 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.16452347 |
| 44 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.13519637 |
| 45 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.12363869 |
| 46 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.11578350 |
| 47 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.10876542 |
| 48 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.09774242 |
| 49 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.06552542 |
| 50 | Huntingtons disease_Homo sapiens_hsa05016 | 1.04172819 |
| 51 | Mineral absorption_Homo sapiens_hsa04978 | 1.03376368 |
| 52 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.99094748 |
| 53 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.98946154 |
| 54 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.97880441 |
| 55 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.97591128 |
| 56 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.97580117 |
| 57 | Lysosome_Homo sapiens_hsa04142 | 0.95555863 |
| 58 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.95023104 |
| 59 | Renin secretion_Homo sapiens_hsa04924 | 0.94271665 |
| 60 | Peroxisome_Homo sapiens_hsa04146 | 0.93707691 |
| 61 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.93694708 |
| 62 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.93525369 |
| 63 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.92865116 |
| 64 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.91144351 |
| 65 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.89670101 |
| 66 | Histidine metabolism_Homo sapiens_hsa00340 | 0.87834827 |
| 67 | RNA polymerase_Homo sapiens_hsa03020 | 0.86194158 |
| 68 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.84753550 |
| 69 | Bile secretion_Homo sapiens_hsa04976 | 0.83978077 |
| 70 | Prion diseases_Homo sapiens_hsa05020 | 0.83163648 |
| 71 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.83142864 |
| 72 | Basal transcription factors_Homo sapiens_hsa03022 | 0.82665061 |
| 73 | Long-term depression_Homo sapiens_hsa04730 | 0.81489684 |
| 74 | Insulin resistance_Homo sapiens_hsa04931 | 0.80461258 |
| 75 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.79191948 |
| 76 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.78486624 |
| 77 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.78310754 |
| 78 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.78147916 |
| 79 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.77516387 |
| 80 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.76479813 |
| 81 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.75849782 |
| 82 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.73245906 |
| 83 | Alcoholism_Homo sapiens_hsa05034 | 0.73227648 |
| 84 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.71729548 |
| 85 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.69777646 |
| 86 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.68526269 |
| 87 | Nicotine addiction_Homo sapiens_hsa05033 | 0.68099950 |
| 88 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.67889065 |
| 89 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.66940928 |
| 90 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.66510387 |
| 91 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.65731499 |
| 92 | Gap junction_Homo sapiens_hsa04540 | 0.64933142 |
| 93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.64856142 |
| 94 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.63938102 |
| 95 | Salivary secretion_Homo sapiens_hsa04970 | 0.63586224 |
| 96 | Other glycan degradation_Homo sapiens_hsa00511 | 0.62658255 |
| 97 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.61167428 |
| 98 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.59866703 |
| 99 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.59423661 |
| 100 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.59202621 |
| 101 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.59054049 |
| 102 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.59030039 |
| 103 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.55639438 |
| 104 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.55219791 |
| 105 | ABC transporters_Homo sapiens_hsa02010 | 0.54405326 |
| 106 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.54215366 |
| 107 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.54158504 |
| 108 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.52759180 |
| 109 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.52278194 |
| 110 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.52018436 |
| 111 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51392035 |
| 112 | Metabolic pathways_Homo sapiens_hsa01100 | 0.50433836 |
| 113 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.50161168 |
| 114 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.49707016 |
| 115 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.49622868 |
| 116 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.48982697 |
| 117 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.48900354 |
| 118 | Melanogenesis_Homo sapiens_hsa04916 | 0.48669146 |
| 119 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.47490060 |
| 120 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.47365987 |
| 121 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.46770351 |
| 122 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.45620039 |
| 123 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.44353301 |
| 124 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.42928782 |
| 125 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.42670211 |
| 126 | Galactose metabolism_Homo sapiens_hsa00052 | 0.42311365 |
| 127 | Glioma_Homo sapiens_hsa05214 | 0.42268674 |
| 128 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.41762902 |
| 129 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.41519324 |
| 130 | Endometrial cancer_Homo sapiens_hsa05213 | 0.39900897 |
| 131 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.38664497 |
| 132 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.38619581 |
| 133 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.38511025 |
| 134 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.38137477 |
| 135 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.37345825 |
| 136 | Thyroid cancer_Homo sapiens_hsa05216 | 0.36735722 |
| 137 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.32253428 |
| 138 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.31956452 |
| 139 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.30904826 |
| 140 | Prostate cancer_Homo sapiens_hsa05215 | 0.30031288 |
| 141 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.29971147 |
| 142 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.29092594 |
| 143 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.27720880 |
| 144 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.27627851 |
| 145 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.25995256 |
| 146 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.25563039 |
| 147 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.24199394 |
| 148 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.23191287 |

