STK33

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm-egg recognition (GO:0035036)9.98414133
2multicellular organism reproduction (GO:0032504)9.93256512
3piRNA metabolic process (GO:0034587)9.53530019
4plasma membrane fusion (GO:0045026)9.32025245
5cell wall macromolecule catabolic process (GO:0016998)9.25152130
6cell wall macromolecule metabolic process (GO:0044036)9.25152130
7acrosome reaction (GO:0007340)9.20509426
8binding of sperm to zona pellucida (GO:0007339)9.12098806
9cell-cell recognition (GO:0009988)8.88464301
10male meiosis (GO:0007140)8.56024987
11spermatid development (GO:0007286)8.54183063
12reproduction (GO:0000003)8.09054566
13regulation of cilium movement (GO:0003352)7.96047962
14synaptonemal complex organization (GO:0070193)7.76071606
15synaptonemal complex assembly (GO:0007130)7.10915940
16single fertilization (GO:0007338)6.95765588
17ventricular system development (GO:0021591)6.72059401
18male meiosis I (GO:0007141)6.47878861
19negative regulation of inclusion body assembly (GO:0090084)6.20137878
20axoneme assembly (GO:0035082)6.15334467
21DNA methylation involved in gamete generation (GO:0043046)6.07870869
22fertilization (GO:0009566)6.04883244
23sperm capacitation (GO:0048240)6.03180555
24spermatogenesis (GO:0007283)5.69285563
25male gamete generation (GO:0048232)5.67189802
26meiosis I (GO:0007127)5.28284766
27gamete generation (GO:0007276)5.22677072
28meiotic nuclear division (GO:0007126)5.11873396
29chromosome organization involved in meiosis (GO:0070192)5.08582812
30regulation of inclusion body assembly (GO:0090083)5.03061659
31germ cell development (GO:0007281)4.94206028
32intraciliary transport (GO:0042073)4.93518621
33microtubule depolymerization (GO:0007019)4.92090943
34cellular process involved in reproduction in multicellular organism (GO:0022412)4.85624827
35organic cation transport (GO:0015695)4.79697010
36regulation of microtubule-based movement (GO:0060632)4.79692468
37centriole assembly (GO:0098534)4.64670091
38meiotic cell cycle (GO:0051321)4.63837998
39microtubule severing (GO:0051013)4.54885175
40seminiferous tubule development (GO:0072520)4.52925362
41protein localization to cilium (GO:0061512)4.51642230
42nucleoside diphosphate phosphorylation (GO:0006165)4.48216537
43GTP biosynthetic process (GO:0006183)4.42945615
44cell recognition (GO:0008037)4.38011789
45left/right pattern formation (GO:0060972)4.30099101
46cilium organization (GO:0044782)4.18448636
47calcium ion-dependent exocytosis (GO:0017156)4.13651299
48multicellular organismal reproductive process (GO:0048609)4.09396827
49photoreceptor cell maintenance (GO:0045494)3.98992146
50microtubule-based movement (GO:0007018)3.98978080
51centriole replication (GO:0007099)3.98381263
52protein polyglutamylation (GO:0018095)3.97859183
53UTP biosynthetic process (GO:0006228)3.97177472
54cilium assembly (GO:0042384)3.96833942
55spermatid nucleus differentiation (GO:0007289)3.89090035
56tryptophan catabolic process (GO:0006569)3.79304139
57indole-containing compound catabolic process (GO:0042436)3.79304139
58indolalkylamine catabolic process (GO:0046218)3.79304139
59left/right axis specification (GO:0070986)3.77746350
60neural tube formation (GO:0001841)3.76952787
61cellular component assembly involved in morphogenesis (GO:0010927)3.66878547
62nonmotile primary cilium assembly (GO:0035058)3.66441954
63indolalkylamine metabolic process (GO:0006586)3.63323076
64UTP metabolic process (GO:0046051)3.61797981
65protein refolding (GO:0042026)3.57205288
66detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.54682949
67cilium morphogenesis (GO:0060271)3.51594254
68genitalia morphogenesis (GO:0035112)3.51366214
69chaperone-mediated protein complex assembly (GO:0051131)3.50678962
70gene silencing by RNA (GO:0031047)3.50429950
71retinal cone cell development (GO:0046549)3.34597219
72meiotic cell cycle process (GO:1903046)3.32906513
73regulation of centriole replication (GO:0046599)3.32491445
74kynurenine metabolic process (GO:0070189)3.28419881
75multicellular organismal development (GO:0007275)3.22295025
76behavioral response to nicotine (GO:0035095)3.19549359
77negative regulation of translation, ncRNA-mediated (GO:0040033)3.17889124
78regulation of translation, ncRNA-mediated (GO:0045974)3.17889124
79negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.17889124
80negative regulation of organelle assembly (GO:1902116)3.17868399
81tryptophan metabolic process (GO:0006568)3.12735695
82establishment of protein localization to Golgi (GO:0072600)3.12208395
83signal peptide processing (GO:0006465)3.12062150
84monoubiquitinated protein deubiquitination (GO:0035520)3.10838339
85cellular ketone body metabolic process (GO:0046950)3.10749701
86glycerol ether metabolic process (GO:0006662)3.10275149
87microtubule bundle formation (GO:0001578)3.09962820
88synapsis (GO:0007129)3.09927206
89detection of light stimulus involved in visual perception (GO:0050908)3.08806723
90detection of light stimulus involved in sensory perception (GO:0050962)3.08806723
91regulation of sarcomere organization (GO:0060297)3.07916889
92chromosome condensation (GO:0030261)3.07341009
93guanosine-containing compound biosynthetic process (GO:1901070)3.04824032
94regulation of meiosis I (GO:0060631)3.02258699
95limb development (GO:0060173)3.00314593
96appendage development (GO:0048736)3.00314593
97negative regulation of cytosolic calcium ion concentration (GO:0051481)2.99248587
98smoothened signaling pathway (GO:0007224)2.99103334
99spinal cord motor neuron differentiation (GO:0021522)2.98437761
100reflex (GO:0060004)2.97880023
101DNA packaging (GO:0006323)2.97014188
102CTP metabolic process (GO:0046036)2.93882650
103CTP biosynthetic process (GO:0006241)2.93882650
104regulation of pigment cell differentiation (GO:0050932)2.93525390
105regulation of hippo signaling (GO:0035330)2.89819655
106regulation of gene silencing by RNA (GO:0060966)2.89358092
107regulation of posttranscriptional gene silencing (GO:0060147)2.89358092
108regulation of gene silencing by miRNA (GO:0060964)2.89358092
109interkinetic nuclear migration (GO:0022027)2.87990940
110ether metabolic process (GO:0018904)2.85839695
111behavioral response to ethanol (GO:0048149)2.84109188
112nuclear pore complex assembly (GO:0051292)2.81151497
113lactate metabolic process (GO:0006089)2.80761835
114carnitine transport (GO:0015879)2.79133794
115amino-acid betaine transport (GO:0015838)2.79133794
116benzene-containing compound metabolic process (GO:0042537)2.79046920
117reciprocal meiotic recombination (GO:0007131)2.78227237
118reciprocal DNA recombination (GO:0035825)2.78227237
119carnitine transmembrane transport (GO:1902603)2.77560141
120regulation of collateral sprouting (GO:0048670)2.77143781
121ketone body metabolic process (GO:1902224)2.76513339
122positive regulation of developmental pigmentation (GO:0048087)2.75615998
123regulation of spindle checkpoint (GO:0090231)2.75144526
124L-fucose catabolic process (GO:0042355)2.74143872
125fucose catabolic process (GO:0019317)2.74143872
126L-fucose metabolic process (GO:0042354)2.74143872
127response to pheromone (GO:0019236)2.72681885
128determination of left/right symmetry (GO:0007368)2.71117844
129pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.70256876
130pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.66396471
131indole-containing compound metabolic process (GO:0042430)2.64055685
132mitotic sister chromatid cohesion (GO:0007064)2.63302420
133retinal rod cell development (GO:0046548)2.62421682
134alditol metabolic process (GO:0019400)2.62238834
135microtubule polymerization or depolymerization (GO:0031109)2.61214672
136determination of bilateral symmetry (GO:0009855)2.58708352
137cell projection assembly (GO:0030031)2.58665285
138lateral ventricle development (GO:0021670)2.58541131
139regulation of protein polyubiquitination (GO:1902914)2.56841909
140photoreceptor cell development (GO:0042461)2.55465392
141nucleus organization (GO:0006997)2.52763882
142G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.51514653
143positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.50759341
144DNA integration (GO:0015074)2.50535519
145specification of symmetry (GO:0009799)2.49505837
146snRNA transcription (GO:0009301)2.49438067
147positive regulation of oligodendrocyte differentiation (GO:0048714)2.48242435
148thyroid hormone metabolic process (GO:0042403)2.45837697
149sulfation (GO:0051923)2.43942615
150DNA double-strand break processing (GO:0000729)2.42606619
151oxidative demethylation (GO:0070989)2.41720911
152presynaptic membrane assembly (GO:0097105)2.37196081
153inner ear receptor stereocilium organization (GO:0060122)2.37139660
154central nervous system neuron axonogenesis (GO:0021955)2.36715600
155cellular biogenic amine catabolic process (GO:0042402)2.36463739
156amine catabolic process (GO:0009310)2.36463739
157eye photoreceptor cell development (GO:0042462)2.36079893
158cellular response to sterol (GO:0036315)2.36021116
159transmission of nerve impulse (GO:0019226)2.35588306
160cornea development in camera-type eye (GO:0061303)2.34134592
161gamma-aminobutyric acid transport (GO:0015812)2.32970300
162cilium or flagellum-dependent cell motility (GO:0001539)16.2871135
163axonemal dynein complex assembly (GO:0070286)12.9106388
164fusion of sperm to egg plasma membrane (GO:0007342)12.2811903
165epithelial cilium movement (GO:0003351)11.2933518
166sperm motility (GO:0030317)11.1388279
167cilium movement (GO:0003341)10.9571380
168motile cilium assembly (GO:0044458)10.9138575
169acrosome assembly (GO:0001675)10.1719691
170epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)10.0874712

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.10560148
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.35848583
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.54371232
4GBX2_23144817_ChIP-Seq_PC3_Human3.28853391
5POU3F2_20337985_ChIP-ChIP_501MEL_Human2.62812858
6IGF1R_20145208_ChIP-Seq_DFB_Human2.62775494
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.51696543
8GATA1_26923725_Chip-Seq_HPCs_Mouse2.44377258
9CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.38683219
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.37505682
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.34472017
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.32108338
13TAF15_26573619_Chip-Seq_HEK293_Human2.28888500
14FUS_26573619_Chip-Seq_HEK293_Human2.23672089
15P300_19829295_ChIP-Seq_ESCs_Human2.18370106
16ZNF274_21170338_ChIP-Seq_K562_Hela2.15979834
17SALL1_21062744_ChIP-ChIP_HESCs_Human2.14635938
18EWS_26573619_Chip-Seq_HEK293_Human2.12701677
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.08237042
20AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.07225540
21EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.04255618
22PCGF2_27294783_Chip-Seq_ESCs_Mouse2.02768592
23PIAS1_25552417_ChIP-Seq_VCAP_Human2.01190790
24MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse10.7733512
25CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.98855787
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.96286928
27* SMAD4_21799915_ChIP-Seq_A2780_Human1.95439694
28ELK4_26923725_Chip-Seq_MESODERM_Mouse1.94624717
29* STAT3_23295773_ChIP-Seq_U87_Human1.92223483
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.89406659
31PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.83789118
32NR3C1_21868756_ChIP-Seq_MCF10A_Human1.75827126
33VDR_22108803_ChIP-Seq_LS180_Human1.74294806
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.72106489
35KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.68657812
36STAT6_21828071_ChIP-Seq_BEAS2B_Human1.66370687
37TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.65849770
38SMAD3_21741376_ChIP-Seq_EPCs_Human1.65210345
39* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.64520995
40RBPJ_22232070_ChIP-Seq_NCS_Mouse1.63839559
41WDR5_24793694_ChIP-Seq_LNCAP_Human1.61350180
42AR_21572438_ChIP-Seq_LNCaP_Human1.58907290
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.58484883
44PCGF2_27294783_Chip-Seq_NPCs_Mouse1.56460409
45RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.54950206
46NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.53602744
47FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.52538234
48AR_25329375_ChIP-Seq_VCAP_Human1.50062960
49GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.49596197
50* KAP1_22055183_ChIP-Seq_ESCs_Mouse1.47339648
51RNF2_27304074_Chip-Seq_NSC_Mouse1.46225968
52TAL1_26923725_Chip-Seq_HPCs_Mouse1.46200347
53NFE2_27457419_Chip-Seq_LIVER_Mouse1.45574110
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.44444269
55CBP_20019798_ChIP-Seq_JUKART_Human1.44444269
56SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.42213922
57* TCF4_22108803_ChIP-Seq_LS180_Human1.42206292
58MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.41889212
59RUNX2_22187159_ChIP-Seq_PCA_Human1.41580268
60GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.41096076
61SUZ12_27294783_Chip-Seq_NPCs_Mouse1.40356055
62SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40202312
63* STAT1_17558387_ChIP-Seq_HELA_Human1.38551637
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.38350333
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.37897750
66OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37836739
67SOX2_22085726_ChIP-Seq_NPCs_Mouse1.36700807
68TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.36643652
69HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.36612974
70REST_21632747_ChIP-Seq_MESCs_Mouse1.34892510
71DROSHA_22980978_ChIP-Seq_HELA_Human1.33969937
72RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.32528309
73* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.28707471
74FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28074554
75TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27067865
76POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.27067865
77TP53_16413492_ChIP-PET_HCT116_Human1.26511567
78SOX2_19829295_ChIP-Seq_ESCs_Human1.25486793
79NANOG_19829295_ChIP-Seq_ESCs_Human1.25486793
80TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.24473758
81ARNT_22903824_ChIP-Seq_MCF-7_Human1.23456238
82GATA3_21867929_ChIP-Seq_CD8_Mouse1.22814534
83PRDM14_20953172_ChIP-Seq_ESCs_Human1.22751597
84KDM2B_26808549_Chip-Seq_REH_Human1.22364665
85FLI1_21867929_ChIP-Seq_TH2_Mouse1.21958637
86AHR_22903824_ChIP-Seq_MCF-7_Human1.21466752
87LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.20264958
88MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.19875884
89TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19670699
90MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.17124857
91BMI1_23680149_ChIP-Seq_NPCS_Mouse1.17089935
92FOXM1_26456572_ChIP-Seq_MCF-7_Human1.16638996
93SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.16538411
94EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14975690
95SOX2_21211035_ChIP-Seq_LN229_Gbm1.14526189
96CDX2_22108803_ChIP-Seq_LS180_Human1.14434565
97NANOG_18555785_Chip-Seq_ESCs_Mouse1.14056268
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13046807
99ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.12675901
100ZFP57_27257070_Chip-Seq_ESCs_Mouse1.11720873
101GF1_26923725_Chip-Seq_HPCs_Mouse1.11423865
102OCT4_18555785_Chip-Seq_ESCs_Mouse1.11090848
103FOXA1_21572438_ChIP-Seq_LNCaP_Human1.11022237
104CRX_20693478_ChIP-Seq_RETINA_Mouse1.10946511
105E2F1_18555785_Chip-Seq_ESCs_Mouse1.10399344
106FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09032391
107GATA3_21867929_ChIP-Seq_TH1_Mouse1.08927636
108IRF1_19129219_ChIP-ChIP_H3396_Human1.08184359
109CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05907034
110MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05157681
111TP53_22573176_ChIP-Seq_HFKS_Human1.04770479
112CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03131041
113GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.02788068
114CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.02764311
115RXR_22108803_ChIP-Seq_LS180_Human1.02225770
116P300_18555785_Chip-Seq_ESCs_Mouse1.02019303
117KLF4_18555785_Chip-Seq_ESCs_Mouse1.02015014
118EZH2_27294783_Chip-Seq_NPCs_Mouse1.01831452
119P53_22387025_ChIP-Seq_ESCs_Mouse1.01705041
120* CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01528115
121PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.00594955
122ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00530243
123* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.99473273
124RUNX1_26923725_Chip-Seq_HPCs_Mouse0.99412997
125P53_21459846_ChIP-Seq_SAOS-2_Human0.98423827
126RAD21_21589869_ChIP-Seq_MESCs_Mouse0.98143901
127EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97993753
128OCT4_21477851_ChIP-Seq_ESCs_Mouse0.97380456
129RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.97171546
130PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.97045149
131ERG_20517297_ChIP-Seq_VCAP_Human0.96867795
132CMYC_18555785_Chip-Seq_ESCs_Mouse0.96257620
133SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.96076625
134ESRRB_18555785_Chip-Seq_ESCs_Mouse0.95976545
135FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95870438
136STAT3_18555785_Chip-Seq_ESCs_Mouse0.95581797
137GF1B_26923725_Chip-Seq_HPCs_Mouse0.95476551
138SUZ12_18555785_Chip-Seq_ESCs_Mouse0.93831860
139ER_23166858_ChIP-Seq_MCF-7_Human0.92587306
140BCAT_22108803_ChIP-Seq_LS180_Human0.92207364
141EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.91833155
142SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.90142341
143* TCF4_23295773_ChIP-Seq_U87_Human0.89886754
144EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.89403295
145SMAD4_21741376_ChIP-Seq_EPCs_Human0.89269572
146FOXA1_25329375_ChIP-Seq_VCAP_Human0.89217112
147FOXA1_27270436_Chip-Seq_PROSTATE_Human0.89217112
148SOX9_26525672_Chip-Seq_HEART_Mouse0.88691708
149ZFX_18555785_Chip-Seq_ESCs_Mouse0.87886614
150PU1_27457419_Chip-Seq_LIVER_Mouse0.87414070
151SPI1_26923725_Chip-Seq_HPCs_Mouse0.87391995
152STAT3_18555785_ChIP-Seq_MESCs_Mouse0.86329357
153MYC_27129775_Chip-Seq_CORNEA_Mouse0.85433794

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.86198684
2MP0001929_abnormal_gametogenesis5.45832823
3MP0008877_abnormal_DNA_methylation5.05793386
4MP0002653_abnormal_ependyma_morphology4.27281008
5MP0002210_abnormal_sex_determination3.85095357
6MP0001145_abnormal_male_reproductive3.20049609
7MP0002161_abnormal_fertility/fecundity3.16501812
8MP0000653_abnormal_sex_gland2.77050496
9MP0005623_abnormal_meninges_morphology2.55984353
10MP0003195_calcinosis2.34766436
11MP0002160_abnormal_reproductive_system2.24085009
12MP0008057_abnormal_DNA_replication2.21196152
13MP0004043_abnormal_pH_regulation2.18515730
14MP0006292_abnormal_olfactory_placode2.17561562
15MP0001485_abnormal_pinna_reflex2.00063448
16MP0005410_abnormal_fertilization14.1372425
17MP0002837_dystrophic_cardiac_calcinosis1.99002835
18MP0002638_abnormal_pupillary_reflex1.97667899
19MP0002282_abnormal_trachea_morphology1.77487244
20MP0000383_abnormal_hair_follicle1.77001387
21MP0002938_white_spotting1.73783441
22MP0002735_abnormal_chemical_nociception1.60578040
23MP0008789_abnormal_olfactory_epithelium1.58919127
24MP0001486_abnormal_startle_reflex1.57883147
25MP0001501_abnormal_sleep_pattern1.57332151
26MP0005646_abnormal_pituitary_gland1.51230069
27MP0006276_abnormal_autonomic_nervous1.50616773
28MP0008875_abnormal_xenobiotic_pharmacok1.49234925
29MP0004142_abnormal_muscle_tone1.48565380
30MP0001984_abnormal_olfaction1.48042867
31MP0005670_abnormal_white_adipose1.48022333
32MP0009745_abnormal_behavioral_response1.46907248
33MP0009046_muscle_twitch1.43660120
34MP0003937_abnormal_limbs/digits/tail_de1.40189138
35MP0008995_early_reproductive_senescence1.36612001
36MP0003880_abnormal_central_pattern1.35728488
37MP0002272_abnormal_nervous_system1.32877323
38MP0005174_abnormal_tail_pigmentation1.32376790
39MP0005645_abnormal_hypothalamus_physiol1.29217813
40MP0003646_muscle_fatigue1.24382389
41MP0000566_synostosis1.23080955
42MP0005389_reproductive_system_phenotype1.20067893
43MP0003011_delayed_dark_adaptation1.16255829
44MP0002234_abnormal_pharynx_morphology1.15637462
45MP0004145_abnormal_muscle_electrophysio1.14156970
46MP0005647_abnormal_sex_gland1.12264133
47MP0003787_abnormal_imprinting1.11783421
48MP0008058_abnormal_DNA_repair1.11169140
49MP0003136_yellow_coat_color1.10354428
50MP0010386_abnormal_urinary_bladder1.09977655
51MP0002168_other_aberrant_phenotype1.09429582
52MP0003718_maternal_effect1.08430526
53MP0002064_seizures1.08130852
54MP0002095_abnormal_skin_pigmentation1.07761116
55MP0002067_abnormal_sensory_capabilities1.07757694
56MP0000026_abnormal_inner_ear1.06877248
57MP0002734_abnormal_mechanical_nocicepti1.06648515
58MP0004215_abnormal_myocardial_fiber1.06528785
59MP0001970_abnormal_pain_threshold1.05550209
60MP0005171_absent_coat_pigmentation1.04464303
61MP0001529_abnormal_vocalization1.04433250
62MP0004924_abnormal_behavior1.03384711
63MP0005386_behavior/neurological_phenoty1.03384711
64MP0001963_abnormal_hearing_physiology1.01403118
65MP0004885_abnormal_endolymph1.01356066
66MP0010094_abnormal_chromosome_stability1.00900485
67MP0004233_abnormal_muscle_weight1.00387971
68MP0008872_abnormal_physiological_respon0.98526786
69MP0003786_premature_aging0.97701474
70MP0005395_other_phenotype0.97567041
71MP0003119_abnormal_digestive_system0.97457084
72MP0010678_abnormal_skin_adnexa0.96302238
73MP0004133_heterotaxia0.95932201
74MP0000372_irregular_coat_pigmentation0.91071464
75MP0002876_abnormal_thyroid_physiology0.90851247
76MP0002733_abnormal_thermal_nociception0.89141888
77MP0001765_abnormal_ion_homeostasis0.87160443
78MP0003045_fibrosis0.86366636
79MP0002229_neurodegeneration0.86316885
80MP0003137_abnormal_impulse_conducting0.84934901
81MP0003121_genomic_imprinting0.82386867
82MP0002882_abnormal_neuron_morphology0.80813999
83MP0008007_abnormal_cellular_replicative0.80191004
84MP0004147_increased_porphyrin_level0.80128317
85MP0003635_abnormal_synaptic_transmissio0.79793333
86MP0001545_abnormal_hematopoietic_system0.77584204
87MP0005397_hematopoietic_system_phenotyp0.77584204
88MP0003878_abnormal_ear_physiology0.74845736
89MP0005377_hearing/vestibular/ear_phenot0.74845736
90MP0002928_abnormal_bile_duct0.72922706
91MP0003950_abnormal_plasma_membrane0.72250611
92MP0003115_abnormal_respiratory_system0.70926612
93MP0004808_abnormal_hematopoietic_stem0.65751739
94MP0005253_abnormal_eye_physiology0.64858024
95MP0003861_abnormal_nervous_system0.57881634
96MP0001293_anophthalmia0.57749129
97MP0005391_vision/eye_phenotype0.57053815
98MP0004134_abnormal_chest_morphology0.55108221
99MP0006072_abnormal_retinal_apoptosis0.53853015
100MP0005551_abnormal_eye_electrophysiolog0.52474031
101MP0000358_abnormal_cell_content/0.49430663
102MP0001324_abnormal_eye_pigmentation0.47231260
103MP0000778_abnormal_nervous_system0.46807956
104MP0003942_abnormal_urinary_system0.45935323
105MP0002152_abnormal_brain_morphology0.45779933
106MP0003699_abnormal_female_reproductive0.44522913
107MP0003890_abnormal_embryonic-extraembry0.42766799
108MP0000569_abnormal_digit_pigmentation0.42585983
109MP0002092_abnormal_eye_morphology0.41813926
110MP0002133_abnormal_respiratory_system0.41763322
111MP0005388_respiratory_system_phenotype0.41763322
112MP0001119_abnormal_female_reproductive0.40965013
113MP0002736_abnormal_nociception_after0.40832912
114MP0000049_abnormal_middle_ear0.38977236
115MP0001440_abnormal_grooming_behavior0.38939076
116MP0002084_abnormal_developmental_patter0.38886520
117MP0001727_abnormal_embryo_implantation0.38545275
118MP0002233_abnormal_nose_morphology0.38229920
119MP0005636_abnormal_mineral_homeostasis0.37321846
120MP0000427_abnormal_hair_cycle0.36613592
121MP0002102_abnormal_ear_morphology0.36227964
122MP0003077_abnormal_cell_cycle0.35905218
123MP0003111_abnormal_nucleus_morphology0.34932936
124MP0004264_abnormal_extraembryonic_tissu0.34918908
125MP0000534_abnormal_ureter_morphology0.34102685
126MP0009250_abnormal_appendicular_skeleto0.34099209
127MP0001986_abnormal_taste_sensitivity0.33631927
128MP0000432_abnormal_head_morphology0.33438996
129MP0002116_abnormal_craniofacial_bone0.33324982
130MP0002796_impaired_skin_barrier0.32483602
131MP0005394_taste/olfaction_phenotype0.32176148
132MP0005499_abnormal_olfactory_system0.32176148
133MP0005195_abnormal_posterior_eye0.31952746
134MP0001851_eye_inflammation0.31933115
135MP0002557_abnormal_social/conspecific_i0.30933353
136MP0004811_abnormal_neuron_physiology0.29654639
137MP0008004_abnormal_stomach_pH0.29291156
138MP0010307_abnormal_tumor_latency0.28582953
139MP0003634_abnormal_glial_cell0.28564378
140MP0009115_abnormal_fat_cell0.28410033
141MP0001730_embryonic_growth_arrest0.27745046
142MP0000955_abnormal_spinal_cord0.27063582
143MP0003183_abnormal_peptide_metabolism0.26946579
144MP0008932_abnormal_embryonic_tissue0.26657320
145MP0004270_analgesia0.26296669
146MP0004742_abnormal_vestibular_system0.26289628
147MP0002572_abnormal_emotion/affect_behav0.26238444
148MP0002752_abnormal_somatic_nervous0.26107856
149MP0000631_abnormal_neuroendocrine_gland0.25855634
150MP0002108_abnormal_muscle_morphology0.25560017
151MP0004858_abnormal_nervous_system0.25351574
152MP0003936_abnormal_reproductive_system0.25076500
153MP0001968_abnormal_touch/_nociception0.24690669
154MP0001270_distended_abdomen0.23818815
155MP0005423_abnormal_somatic_nervous0.23622527

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.36596649
2Abnormal respiratory epithelium morphology (HP:0012253)9.36596649
3Abnormal ciliary motility (HP:0012262)9.13550952
4Rhinitis (HP:0012384)8.98638283
5Chronic bronchitis (HP:0004469)7.73153883
6Nasal polyposis (HP:0100582)6.25375983
7Infertility (HP:0000789)5.70972280
8Bronchiectasis (HP:0002110)5.28417668
9Abnormality of the nasal mucosa (HP:0000433)5.14827640
10Nephronophthisis (HP:0000090)4.46506197
11Bronchitis (HP:0012387)4.42779523
12Abnormality of the renal medulla (HP:0100957)3.43924255
13Recurrent sinusitis (HP:0011108)3.39435960
14Recurrent otitis media (HP:0000403)3.21139562
15Tubulointerstitial nephritis (HP:0001970)3.16628052
16Medial flaring of the eyebrow (HP:0010747)3.01292267
17Abnormality of midbrain morphology (HP:0002418)2.99187879
18Molar tooth sign on MRI (HP:0002419)2.99187879
19Genetic anticipation (HP:0003743)2.98371699
20Abnormality of the lower motor neuron (HP:0002366)2.96124921
21Hyperventilation (HP:0002883)2.78141827
22Male infertility (HP:0003251)2.75324309
23Gaze-evoked nystagmus (HP:0000640)2.69357807
24Tubular atrophy (HP:0000092)2.63058174
25Progressive cerebellar ataxia (HP:0002073)2.62582150
26Fibular hypoplasia (HP:0003038)2.59315505
27Chronic sinusitis (HP:0011109)2.56021197
28Supernumerary spleens (HP:0009799)2.51574865
29Postaxial foot polydactyly (HP:0001830)2.43794339
30Abolished electroretinogram (ERG) (HP:0000550)2.39408089
31Aplasia/Hypoplasia of the tibia (HP:0005772)2.39143408
32Furrowed tongue (HP:0000221)2.38918696
33Tubulointerstitial abnormality (HP:0001969)2.38557773
34Congenital stationary night blindness (HP:0007642)2.37789761
35Central scotoma (HP:0000603)2.36533701
36Pancreatic fibrosis (HP:0100732)2.36366811
37Attenuation of retinal blood vessels (HP:0007843)2.36255844
38Gonadotropin excess (HP:0000837)2.33205200
39Amyotrophic lateral sclerosis (HP:0007354)2.30019361
40Abnormal spermatogenesis (HP:0008669)2.25770277
41Congenital hepatic fibrosis (HP:0002612)2.24141205
42Recurrent bronchitis (HP:0002837)2.22529950
43Bony spicule pigmentary retinopathy (HP:0007737)2.18856625
44Median cleft lip (HP:0000161)2.14323643
45Gait imbalance (HP:0002141)2.13481926
46True hermaphroditism (HP:0010459)2.12547584
47Congenital primary aphakia (HP:0007707)2.11957497
48Facial cleft (HP:0002006)2.07511331
49Absent speech (HP:0001344)2.04156486
50Stage 5 chronic kidney disease (HP:0003774)2.00645794
51Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.9478109
52Absent/shortened dynein arms (HP:0200106)11.8839047
53Dynein arm defect of respiratory motile cilia (HP:0012255)11.8839047
54Abnormal respiratory motile cilium physiology (HP:0012261)10.6634045
55Impaired proprioception (HP:0010831)1.97564799
56Decreased circulating renin level (HP:0003351)1.95835997
57Abnormality of macular pigmentation (HP:0008002)1.93725946
58Protruding tongue (HP:0010808)1.92924783
59Decreased central vision (HP:0007663)1.92733815
60Abnormality of dentin (HP:0010299)1.90243168
61Postaxial hand polydactyly (HP:0001162)1.89679938
62Cystic liver disease (HP:0006706)1.89587536
63Oculomotor apraxia (HP:0000657)1.88534749
64Intestinal atresia (HP:0011100)1.88163307
65Abnormal rod and cone electroretinograms (HP:0008323)1.86367517
66Impulsivity (HP:0100710)1.84914373
67Highly arched eyebrow (HP:0002553)1.84027958
68Nephrogenic diabetes insipidus (HP:0009806)1.83616971
69Congenital sensorineural hearing impairment (HP:0008527)1.83364304
70Renal cortical cysts (HP:0000803)1.82824191
71Type II lissencephaly (HP:0007260)1.82713345
72Aplasia/Hypoplasia of the tongue (HP:0010295)1.81414841
73Broad-based gait (HP:0002136)1.80848225
74Short foot (HP:0001773)1.78781692
75Tubulointerstitial fibrosis (HP:0005576)1.78120979
76Scotoma (HP:0000575)1.77750840
77Narrow forehead (HP:0000341)1.76697542
78Retinitis pigmentosa (HP:0000510)1.76114553
79Febrile seizures (HP:0002373)1.74514772
80Volvulus (HP:0002580)1.73521238
81Prominent nasal bridge (HP:0000426)1.72757093
82Azoospermia (HP:0000027)1.72321895
83Aganglionic megacolon (HP:0002251)1.70098917
84Short ribs (HP:0000773)1.69159155
85Renal dysplasia (HP:0000110)1.68884841
86Multicystic kidney dysplasia (HP:0000003)1.68291004
87Broad foot (HP:0001769)1.68033944
88Abnormality of the dental root (HP:0006486)1.67613478
89Taurodontia (HP:0000679)1.67613478
90Abnormality of permanent molar morphology (HP:0011071)1.67613478
91Oligodactyly (hands) (HP:0001180)1.67249356
92Abnormality of the renal cortex (HP:0011035)1.66566119
93Pancreatic cysts (HP:0001737)1.65826397
94Astigmatism (HP:0000483)1.65163146
95Widely spaced teeth (HP:0000687)1.64002212
96Occipital encephalocele (HP:0002085)1.63730967
97Dandy-Walker malformation (HP:0001305)1.63152676
98Abnormal biliary tract physiology (HP:0012439)1.63112273
99Bile duct proliferation (HP:0001408)1.63112273
100Aplasia/Hypoplasia of the fibula (HP:0006492)1.62991861
10111 pairs of ribs (HP:0000878)1.62523365
102Cerebellar dysplasia (HP:0007033)1.62200680
103Hypoplasia of the capital femoral epiphysis (HP:0003090)1.62193976
104Genital tract atresia (HP:0001827)1.62059967
105Abnormality of the anterior horn cell (HP:0006802)1.61622241
106Degeneration of anterior horn cells (HP:0002398)1.61622241
107Keratoconus (HP:0000563)1.60876487
108Increased corneal curvature (HP:0100692)1.60876487
109Specific learning disability (HP:0001328)1.60482768
110Microglossia (HP:0000171)1.59928661
111Absent rod-and cone-mediated responses on ERG (HP:0007688)1.59675125
112Poor coordination (HP:0002370)1.58637387
113Large for gestational age (HP:0001520)1.58251868
114Polydipsia (HP:0001959)1.58164923
115Abnormal drinking behavior (HP:0030082)1.58164923
116Sloping forehead (HP:0000340)1.57925524
117Fair hair (HP:0002286)1.57103776
118Abnormality of molar morphology (HP:0011070)1.56058787
119Abnormality of molar (HP:0011077)1.56058787
120Vaginal atresia (HP:0000148)1.55815690
121Hyperkalemia (HP:0002153)1.54957886
122Bell-shaped thorax (HP:0001591)1.54500714
123Chorioretinal atrophy (HP:0000533)1.54385855
124Polyuria (HP:0000103)1.53280238
125Upper motor neuron abnormality (HP:0002127)1.53084422
126Abnormality of the dental pulp (HP:0006479)1.50184949
127Aplasia/Hypoplasia of the lens (HP:0008063)1.49919510
128Broad distal phalanx of finger (HP:0009836)1.39638468
129Absent frontal sinuses (HP:0002688)1.39087849
130Chronic hepatic failure (HP:0100626)1.35450445
131Short thorax (HP:0010306)1.34547817
132Nephropathy (HP:0000112)1.31553174
133Heterotopia (HP:0002282)1.31018625
134Anencephaly (HP:0002323)1.30699472
135Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.26117700
136Absent epiphyses (HP:0010577)1.26117700
137Abnormality of renal excretion (HP:0011036)1.26108759
138Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.23670271
139Preaxial hand polydactyly (HP:0001177)1.22848827
140J-shaped sella turcica (HP:0002680)1.22567990
141Bifid tongue (HP:0010297)1.17183324
142Sclerocornea (HP:0000647)1.16830141
143Pachygyria (HP:0001302)1.14209748
144Male pseudohermaphroditism (HP:0000037)1.11683051
145Abnormality of ocular smooth pursuit (HP:0000617)1.11636560
146Breast carcinoma (HP:0003002)1.10056321
147Spastic tetraparesis (HP:0001285)1.09895624
148Abnormality of abdominal situs (HP:0011620)1.08051690

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.50113659
2PDK48.50113659
3FRK7.66895810
4PDK25.44186728
5TESK14.43092737
6PRKD33.92151574
7PNCK3.68976877
8ICK3.28946503
9ACVR1B3.06696664
10INSRR2.81506236
11MAPK152.34932473
12PTK2B2.32879136
13MAP4K22.23544906
14WNK42.20456475
15STK392.16662343
16ADRBK22.11255170
17NEK21.98060211
18TNIK1.88517146
19CASK1.83900421
20NUAK11.72623480
21MKNK21.68803257
22ZAK1.65914272
23CCNB11.65025201
24LATS11.49571725
25MAPK131.46070752
26OXSR11.41320794
27STK381.24131094
28TYRO31.19671018
29DYRK1B1.18782018
30WEE11.18527896
31BCR1.16027946
32WNK11.15940858
33NTRK31.14956239
34MKNK11.14020562
35MST41.08017615
36AKT31.06101163
37DYRK31.05453442
38TLK11.03051571
39CDC70.96259782
40PRKCE0.95034980
41STK30.94768532
42ADRBK10.93729902
43MAP2K70.90903773
44CDK190.89814497
45FGFR20.89563830
46PLK40.86129483
47OBSCN0.85263863
48TAOK30.83230389
49TGFBR10.81803308
50NLK0.76044320
51LMTK20.74204020
52PAK30.73873377
53PIK3CG0.72782339
54EPHA40.72565920
55IRAK10.71494430
56MAP3K70.70917733
57PDK10.70876699
58EPHA30.70364262
59CDK120.68808793
60CAMK1D0.68477201
61PRKAA20.67778639
62TRIM280.66965883
63TTK0.66909097
64DAPK20.66831411
65SGK20.66371448
66BRD40.65859105
67PASK0.63315447
68CHEK20.60466073
69NTRK20.59030096
70CSNK1G20.58806526
71PIK3CA0.57968334
72PKN10.57505669
73PINK10.56493860
74TEC0.55229336
75TNK20.54086255
76TAF10.53776652
77CSNK1G10.53446062
78CSNK1A1L0.52736430
79CAMKK20.52275565
80CAMK10.51645734
81CHEK10.51632109
82CAMK2A0.49554097
83ERBB20.49303595
84EIF2AK30.45953880
85DYRK20.43640814
86ATR0.42674679
87DYRK1A0.41378181
88ATM0.40571151
89SGK2230.40033527
90SGK4940.40033527
91PLK30.39256498
92TXK0.38372602
93CAMK1G0.38136296
94STK100.37642399
95PLK10.37349235
96NME10.37288512
97STK38L0.37166811
98CSNK1G30.36393338
99YES10.36225109
100PAK20.35541166
101TIE10.34901784
102MELK0.34389021
103PRKCG0.33888041
104CSNK1A10.32677407
105GRK50.32414945
106NEK60.31670806
107PAK10.30088551
108MAP2K60.30084823
109AURKA0.27289826
110IRAK20.25439535
111BRSK20.24019858
112BMPR1B0.23732875
113MTOR0.22280395
114GRK10.20454984
115PRKAA10.20136350
116ERBB30.17774639
117MARK20.17657828
118WNK30.17635134
119MAP3K40.16529783
120MARK10.15085946
121PDPK10.14697005
122BRSK10.14681019
123CSNK2A10.13166829
124GRK70.12760551
125SRPK10.12621496
126FER0.12585797
127TESK20.10818875
128MUSK0.10671580
129CAMKK10.10321443
130RPS6KB10.09762160
131CDK30.09657261
132PLK20.09567886
133PRKCZ0.09023433
134PRKACB0.08622152
135CDK10.08531824
136PRKG10.08258409
137PRKACG0.07618591
138PRKDC0.07113240
139GSK3B0.06571863
140CDK20.06421152
141VRK10.06371793
142CDK150.06154529
143CDK180.05621155
144RPS6KA10.05347778
145CSNK1D0.05282672
146MAPK100.04558488
147CSNK2A20.04393535
148PAK40.03171419
149GSK3A0.02739556
150RPS6KA30.02176160
151EGFR0.02162906
152CDK11A0.02128366
153PRKACA0.01796764
154CDK140.01789671
155CSNK1E0.01662215
156MAPK80.01503545
157MINK10.01431217
158STK110.01111662
159CSK0.00723725
160MAPKAPK50.00638034
161TGFBR20.00467615
162INSR0.00334167
163CDK70.00328170

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.27923928
2Pyruvate metabolism_Homo sapiens_hsa006204.00810988
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.67433834
4Basal transcription factors_Homo sapiens_hsa030223.27928142
5Fatty acid biosynthesis_Homo sapiens_hsa000613.22499215
6Propanoate metabolism_Homo sapiens_hsa006402.91952401
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.86139702
8Butanoate metabolism_Homo sapiens_hsa006502.76975073
9Dorso-ventral axis formation_Homo sapiens_hsa043202.71759016
10Glucagon signaling pathway_Homo sapiens_hsa049222.60032268
11Huntingtons disease_Homo sapiens_hsa050162.59650279
12Fanconi anemia pathway_Homo sapiens_hsa034602.54936520
13Phototransduction_Homo sapiens_hsa047442.45785371
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.44851428
15Linoleic acid metabolism_Homo sapiens_hsa005912.39147117
16Nicotine addiction_Homo sapiens_hsa050332.28643712
17Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.21982203
18Selenocompound metabolism_Homo sapiens_hsa004502.12843025
19Tryptophan metabolism_Homo sapiens_hsa003802.12588600
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.09009862
21Oocyte meiosis_Homo sapiens_hsa041142.07370378
22Maturity onset diabetes of the young_Homo sapiens_hsa049501.96866052
23Pentose phosphate pathway_Homo sapiens_hsa000301.88380544
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.81714597
25Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.80691589
26Glycerolipid metabolism_Homo sapiens_hsa005611.78274514
27Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.71036151
28Amphetamine addiction_Homo sapiens_hsa050311.68470466
29beta-Alanine metabolism_Homo sapiens_hsa004101.68232972
30Nitrogen metabolism_Homo sapiens_hsa009101.66084440
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.65684128
32Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.65589331
33Histidine metabolism_Homo sapiens_hsa003401.56577477
34mRNA surveillance pathway_Homo sapiens_hsa030151.54502838
35Steroid hormone biosynthesis_Homo sapiens_hsa001401.54261834
36PPAR signaling pathway_Homo sapiens_hsa033201.53081965
37Caffeine metabolism_Homo sapiens_hsa002321.45382377
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.43989616
39Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.42323766
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.40926675
41Fructose and mannose metabolism_Homo sapiens_hsa000511.37610182
42Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.34637774
43Cysteine and methionine metabolism_Homo sapiens_hsa002701.28854973
44Antigen processing and presentation_Homo sapiens_hsa046121.27040210
45Glycerophospholipid metabolism_Homo sapiens_hsa005641.26732194
46Cardiac muscle contraction_Homo sapiens_hsa042601.26647289
47Renin secretion_Homo sapiens_hsa049241.26184755
48RNA transport_Homo sapiens_hsa030131.25779230
49Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.24749742
50Peroxisome_Homo sapiens_hsa041461.23845568
51Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.23570313
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.20537553
53Morphine addiction_Homo sapiens_hsa050321.18240015
54Glycosaminoglycan degradation_Homo sapiens_hsa005311.17780562
55Ether lipid metabolism_Homo sapiens_hsa005651.16684848
56Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.16415936
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.16084797
58Serotonergic synapse_Homo sapiens_hsa047261.13581872
59Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.12905579
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.12631043
61Purine metabolism_Homo sapiens_hsa002301.10696952
62Hedgehog signaling pathway_Homo sapiens_hsa043401.10151907
63Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.08815296
64Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.08344831
65Non-homologous end-joining_Homo sapiens_hsa034501.08152408
66Glutathione metabolism_Homo sapiens_hsa004801.07318126
67Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.07024025
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.07002937
69RNA polymerase_Homo sapiens_hsa030201.02687538
70Mineral absorption_Homo sapiens_hsa049781.00849499
71Ovarian steroidogenesis_Homo sapiens_hsa049130.97597490
72Carbon metabolism_Homo sapiens_hsa012000.96514384
73GABAergic synapse_Homo sapiens_hsa047270.96166582
74Lysine degradation_Homo sapiens_hsa003100.95827751
75Arachidonic acid metabolism_Homo sapiens_hsa005900.94541380
76Circadian rhythm_Homo sapiens_hsa047100.91014868
77Fat digestion and absorption_Homo sapiens_hsa049750.87294559
78Estrogen signaling pathway_Homo sapiens_hsa049150.85883576
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84132282
80Chemical carcinogenesis_Homo sapiens_hsa052040.81677788
81Protein export_Homo sapiens_hsa030600.80516187
82Regulation of autophagy_Homo sapiens_hsa041400.77626674
83Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.76677919
84Long-term potentiation_Homo sapiens_hsa047200.75968020
85Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.73715521
86Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.72538333
87Homologous recombination_Homo sapiens_hsa034400.67871877
88Calcium signaling pathway_Homo sapiens_hsa040200.66291480
89Wnt signaling pathway_Homo sapiens_hsa043100.64385317
90Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.62427010
91AMPK signaling pathway_Homo sapiens_hsa041520.60866249
92Cell cycle_Homo sapiens_hsa041100.59980578
93ABC transporters_Homo sapiens_hsa020100.59849136
94Fatty acid metabolism_Homo sapiens_hsa012120.58555154
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58335683
96Basal cell carcinoma_Homo sapiens_hsa052170.54749575
97Taste transduction_Homo sapiens_hsa047420.54414574
98Systemic lupus erythematosus_Homo sapiens_hsa053220.54205777
99cGMP-PKG signaling pathway_Homo sapiens_hsa040220.54110871
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51584366
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.51098001
102Cholinergic synapse_Homo sapiens_hsa047250.51004609
103Aldosterone synthesis and secretion_Homo sapiens_hsa049250.50186294
104Dopaminergic synapse_Homo sapiens_hsa047280.48185034
105Long-term depression_Homo sapiens_hsa047300.47797443
106Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.47419618
107Biosynthesis of amino acids_Homo sapiens_hsa012300.47101500
108Tyrosine metabolism_Homo sapiens_hsa003500.46728008
109One carbon pool by folate_Homo sapiens_hsa006700.44794561
110Pyrimidine metabolism_Homo sapiens_hsa002400.44774241
111Insulin secretion_Homo sapiens_hsa049110.44308096
112Oxytocin signaling pathway_Homo sapiens_hsa049210.43882538
113Hippo signaling pathway_Homo sapiens_hsa043900.43882304
114Type II diabetes mellitus_Homo sapiens_hsa049300.43780741
115TGF-beta signaling pathway_Homo sapiens_hsa043500.43494649
116Collecting duct acid secretion_Homo sapiens_hsa049660.43338593
117Pancreatic secretion_Homo sapiens_hsa049720.42729032
118Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.42122034
119Fatty acid degradation_Homo sapiens_hsa000710.41942210
120Adipocytokine signaling pathway_Homo sapiens_hsa049200.39609312
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.38639096
122Vitamin digestion and absorption_Homo sapiens_hsa049770.38499692
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37499429
124N-Glycan biosynthesis_Homo sapiens_hsa005100.37306304
125VEGF signaling pathway_Homo sapiens_hsa043700.37084944
126Thyroid hormone synthesis_Homo sapiens_hsa049180.36749734
127Endocytosis_Homo sapiens_hsa041440.36392270
128Viral carcinogenesis_Homo sapiens_hsa052030.36236678
129Gastric acid secretion_Homo sapiens_hsa049710.35573216
130Inositol phosphate metabolism_Homo sapiens_hsa005620.35157804
131Alcoholism_Homo sapiens_hsa050340.34214006
132Metabolic pathways_Homo sapiens_hsa011000.33290225
133Transcriptional misregulation in cancer_Homo sapiens_hsa052020.33221312
134Retinol metabolism_Homo sapiens_hsa008300.32218831
135Nucleotide excision repair_Homo sapiens_hsa034200.31827712
136Renin-angiotensin system_Homo sapiens_hsa046140.30483656
137Circadian entrainment_Homo sapiens_hsa047130.29683386
138Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.26334629
139Tight junction_Homo sapiens_hsa045300.25468046
140Vascular smooth muscle contraction_Homo sapiens_hsa042700.25272898
141Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25040177
142Synaptic vesicle cycle_Homo sapiens_hsa047210.24285802
143Epstein-Barr virus infection_Homo sapiens_hsa051690.24053609
144cAMP signaling pathway_Homo sapiens_hsa040240.23958489
145RNA degradation_Homo sapiens_hsa030180.22802013
146Olfactory transduction_Homo sapiens_hsa047400.22176327
147Glutamatergic synapse_Homo sapiens_hsa047240.21926199
148Sphingolipid metabolism_Homo sapiens_hsa006000.20869972
149Salivary secretion_Homo sapiens_hsa049700.20744428
150Cocaine addiction_Homo sapiens_hsa050300.20496513
151Protein digestion and absorption_Homo sapiens_hsa049740.18898065

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