STMN1P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.79845844
2rRNA catabolic process (GO:0016075)4.59952811
3neutrophil activation involved in immune response (GO:0002283)4.52466549
4dosage compensation (GO:0007549)4.37456797
5cell wall macromolecule metabolic process (GO:0044036)4.37117252
6attachment of spindle microtubules to kinetochore (GO:0008608)4.33793375
7regulation of mitotic spindle organization (GO:0060236)4.30204350
8base-excision repair, AP site formation (GO:0006285)4.27675227
9autophagic vacuole fusion (GO:0000046)4.05674909
10phosphorelay signal transduction system (GO:0000160)4.03526984
11NIK/NF-kappaB signaling (GO:0038061)4.00637905
12pyrimidine nucleotide catabolic process (GO:0006244)3.99112281
13synapsis (GO:0007129)3.76092823
14estrogen biosynthetic process (GO:0006703)3.72538021
15positive regulation of gamma-delta T cell activation (GO:0046645)3.71481590
16positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.68309632
17negative regulation of necroptotic process (GO:0060546)3.66875044
18histone H3-K4 trimethylation (GO:0080182)3.66330417
19cytochrome complex assembly (GO:0017004)3.65843784
20positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.62632720
21positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.62632720
22positive regulation of mitotic sister chromatid separation (GO:1901970)3.62632720
23exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.59525682
24kinetochore organization (GO:0051383)3.57141051
25establishment of protein localization to mitochondrial membrane (GO:0090151)3.51886247
26anterograde synaptic vesicle transport (GO:0048490)3.51286893
27positive regulation of B cell differentiation (GO:0045579)3.49953463
28regulation of B cell receptor signaling pathway (GO:0050855)3.49270757
29organelle membrane fusion (GO:0090174)3.47011850
30nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.46377283
31negative thymic T cell selection (GO:0045060)3.37920030
32regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.28617147
33regulation of spindle organization (GO:0090224)3.26725093
34hepatocyte apoptotic process (GO:0097284)3.25953317
35mitotic G2 DNA damage checkpoint (GO:0007095)3.20928325
36kinetochore assembly (GO:0051382)3.19869746
37activated T cell proliferation (GO:0050798)3.17704693
38positive regulation of mast cell degranulation (GO:0043306)3.16245077
39positive regulation of mast cell activation involved in immune response (GO:0033008)3.16245077
40regulation of interferon-beta biosynthetic process (GO:0045357)3.14057111
41positive regulation of histone H3-K4 methylation (GO:0051571)3.13805687
42negative T cell selection (GO:0043383)3.12800779
43mitotic sister chromatid segregation (GO:0000070)3.12382836
44pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.10370677
45retinal rod cell development (GO:0046548)3.07475039
46modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.04601940
47positive regulation by organism of defense response of other organism involved in symbiotic interact3.04601940
48modulation by symbiont of host immune response (GO:0052553)3.04601940
49positive regulation by symbiont of host defense response (GO:0052509)3.04601940
50modulation by symbiont of host defense response (GO:0052031)3.04601940
51modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.04601940
52retinal cone cell development (GO:0046549)3.04470667
53production of molecular mediator involved in inflammatory response (GO:0002532)3.02295054
54DNA deamination (GO:0045006)2.99751481
55respiratory chain complex IV assembly (GO:0008535)2.99205099
56protein destabilization (GO:0031648)2.95855838
57protein K63-linked deubiquitination (GO:0070536)2.94126258
58positive regulation of protein homooligomerization (GO:0032464)2.93108665
59positive regulation of immune response to tumor cell (GO:0002839)2.92683495
60regulation of immune response to tumor cell (GO:0002837)2.92683495
61regulation of response to tumor cell (GO:0002834)2.92683495
62positive regulation of response to tumor cell (GO:0002836)2.92683495
63positive regulation of mast cell activation (GO:0033005)2.91197442
64positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.90219671
65pyrimidine-containing compound transmembrane transport (GO:0072531)2.89268044
66regulation of acute inflammatory response to antigenic stimulus (GO:0002864)2.87771075
67sister chromatid segregation (GO:0000819)2.87180284
68regulation of hypersensitivity (GO:0002883)2.83962120
69pseudouridine synthesis (GO:0001522)2.83731598
70mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.82600669
71positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.82600669
72negative regulation of necrotic cell death (GO:0060547)2.81495383
73regulation of necroptotic process (GO:0060544)2.80054396
74mannosylation (GO:0097502)2.78002371
75phagocytosis, engulfment (GO:0006911)2.77651446
76I-kappaB phosphorylation (GO:0007252)2.75819802
77peptidyl-lysine trimethylation (GO:0018023)2.72755040
78regulation of gamma-delta T cell differentiation (GO:0045586)2.69429914
79response to redox state (GO:0051775)2.69311087
80mitotic G2/M transition checkpoint (GO:0044818)2.69194193
81macrophage activation involved in immune response (GO:0002281)2.68978278
82neutrophil activation (GO:0042119)2.68038184
83ADP metabolic process (GO:0046031)2.66185895
84DNA double-strand break processing (GO:0000729)2.66144494
85positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.65445830
86chaperone-mediated protein transport (GO:0072321)2.65067455
87protein complex biogenesis (GO:0070271)2.63390887
88monoubiquitinated protein deubiquitination (GO:0035520)2.62820457
89positive regulation of granulocyte differentiation (GO:0030854)2.60151068
90nucleotide-excision repair, DNA gap filling (GO:0006297)2.59819443
91cell wall macromolecule catabolic process (GO:0016998)2.59789902
92regulation of RIG-I signaling pathway (GO:0039535)2.59470366
93regulation of mitochondrial translation (GO:0070129)2.59140461
94centriole replication (GO:0007099)2.56019951
95negative regulation of interleukin-12 production (GO:0032695)2.54169388
96leukocyte degranulation (GO:0043299)2.53870947
97regulation of histone H3-K27 methylation (GO:0061085)2.53312739
98mitochondrial respiratory chain complex assembly (GO:0033108)2.52781398
99protein-cofactor linkage (GO:0018065)2.49942729
100protein ADP-ribosylation (GO:0006471)2.49418054

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ELF1_17652178_ChIP-ChIP_JURKAT_Human4.61786997
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.42340887
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.32983332
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.28943792
5HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.26731826
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.09210337
7E2F7_22180533_ChIP-Seq_HELA_Human2.61145017
8CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.44106235
9VDR_23849224_ChIP-Seq_CD4+_Human2.43048841
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.40812848
11IRF8_22096565_ChIP-ChIP_GC-B_Human2.36733796
12FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.27082707
13SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.18507026
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.18169923
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.16665233
16MYC_18555785_ChIP-Seq_MESCs_Mouse2.14853807
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.13696748
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.08792152
19FOXM1_23109430_ChIP-Seq_U2OS_Human2.08061948
20ELK1_19687146_ChIP-ChIP_HELA_Human2.07810609
21CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.01041758
22ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.99378242
23EGR1_19374776_ChIP-ChIP_THP-1_Human1.94654607
24CIITA_25753668_ChIP-Seq_RAJI_Human1.93975298
25FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.89455862
26SRF_21415370_ChIP-Seq_HL-1_Mouse1.88219496
27HOXB4_20404135_ChIP-ChIP_EML_Mouse1.87838886
28KDM5A_27292631_Chip-Seq_BREAST_Human1.87149169
29FOXP3_21729870_ChIP-Seq_TREG_Human1.78114140
30MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.73074207
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.72162171
32MYB_26560356_Chip-Seq_TH2_Human1.71635166
33FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.69845601
34ETS1_20019798_ChIP-Seq_JURKAT_Human1.68784717
35MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.68193466
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67885973
37PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.65888993
38STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.65273681
39SPI1_23547873_ChIP-Seq_NB4_Human1.63279528
40STAT4_19710469_ChIP-ChIP_TH1__Mouse1.61641092
41CREB1_15753290_ChIP-ChIP_HEK293T_Human1.61278591
42VDR_22108803_ChIP-Seq_LS180_Human1.59085827
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.58525803
44EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.56870469
45BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.55572563
46BP1_19119308_ChIP-ChIP_Hs578T_Human1.54717739
47SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.50907434
48GABP_19822575_ChIP-Seq_HepG2_Human1.49703459
49SCL_19346495_ChIP-Seq_HPC-7_Human1.47369938
50ERG_20887958_ChIP-Seq_HPC-7_Mouse1.45370093
51GATA1_19941826_ChIP-Seq_K562_Human1.43959408
52TFEB_21752829_ChIP-Seq_HELA_Human1.42994457
53ZNF274_21170338_ChIP-Seq_K562_Hela1.41420462
54GATA3_26560356_Chip-Seq_TH2_Human1.36192731
55MYC_18358816_ChIP-ChIP_MESCs_Mouse1.34548479
56NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.32992761
57IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.32594487
58PADI4_21655091_ChIP-ChIP_MCF-7_Human1.32541290
59KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.32446724
60E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.30409881
61TTF2_22483619_ChIP-Seq_HELA_Human1.29272195
62YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27966101
63MYB_26560356_Chip-Seq_TH1_Human1.26630648
64SPI1_23127762_ChIP-Seq_K562_Human1.26520071
65E2F1_21310950_ChIP-Seq_MCF-7_Human1.25489145
66IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.24056945
67GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.23877085
68IRF8_21731497_ChIP-ChIP_J774_Mouse1.22071622
69YY1_21170310_ChIP-Seq_MESCs_Mouse1.21999590
70GATA2_19941826_ChIP-Seq_K562_Human1.21386118
71LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.20809180
72TP53_22573176_ChIP-Seq_HFKS_Human1.19876547
73GATA3_27048872_Chip-Seq_THYMUS_Human1.17240332
74RUNX_20019798_ChIP-Seq_JUKART_Human1.16661804
75MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.16415217
76MAF_26560356_Chip-Seq_TH1_Human1.14223698
77NOTCH1_21737748_ChIP-Seq_TLL_Human1.13728057
78MYC_19030024_ChIP-ChIP_MESCs_Mouse1.12689737
79E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.08039493
80GATA2_22383799_ChIP-Seq_G1ME_Mouse1.06029597
81NCOR1_26117541_ChIP-Seq_K562_Human1.05250423
82GATA1_22025678_ChIP-Seq_K562_Human1.04407590
83THAP11_20581084_ChIP-Seq_MESCs_Mouse1.03132986
84RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.02005240
85FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01461874
86MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.00381265
87STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.99007312
88E2F1_18555785_ChIP-Seq_MESCs_Mouse0.98731245
89CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.97444462
90P300_27268052_Chip-Seq_Bcells_Human0.96193388
91NELFA_20434984_ChIP-Seq_ESCs_Mouse0.96184897
92MYC_22102868_ChIP-Seq_BL_Human0.94800056
93ELK1_22589737_ChIP-Seq_MCF10A_Human0.94788675
94RBPJ_21746931_ChIP-Seq_IB4_Human0.91906117
95PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.90171815
96LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.90152088
97FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.88310722
98MAF_26560356_Chip-Seq_TH2_Human0.88267078
99CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.86407517
100MYCN_18555785_ChIP-Seq_MESCs_Mouse0.84709324

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003787_abnormal_imprinting4.23847710
2MP0008877_abnormal_DNA_methylation3.91494029
3MP0008007_abnormal_cellular_replicative3.17999517
4MP0009333_abnormal_splenocyte_physiolog3.08459494
5MP0005408_hypopigmentation2.87337256
6MP0006292_abnormal_olfactory_placode2.42055033
7MP0002877_abnormal_melanocyte_morpholog2.41535425
8MP0003303_peritoneal_inflammation2.31078533
9MP0003646_muscle_fatigue2.29790113
10MP0010094_abnormal_chromosome_stability2.26222577
11MP0002638_abnormal_pupillary_reflex2.24821436
12MP0005083_abnormal_biliary_tract2.15676000
13MP0000372_irregular_coat_pigmentation2.11729766
14MP0002132_abnormal_respiratory_system1.97132304
15MP0001835_abnormal_antigen_presentation1.96083182
16MP0000569_abnormal_digit_pigmentation1.94105610
17MP0001800_abnormal_humoral_immune1.93073832
18MP0008058_abnormal_DNA_repair1.85402030
19MP0008995_early_reproductive_senescence1.84113080
20MP0003724_increased_susceptibility_to1.81932459
21MP0003122_maternal_imprinting1.81235770
22MP0003786_premature_aging1.79542939
23MP0003436_decreased_susceptibility_to1.78806329
24MP0002396_abnormal_hematopoietic_system1.77492292
25MP0003121_genomic_imprinting1.71802017
26MP0005084_abnormal_gallbladder_morpholo1.69884201
27MP0004381_abnormal_hair_follicle1.69574809
28MP0003763_abnormal_thymus_physiology1.68824732
29MP0002160_abnormal_reproductive_system1.63530076
30MP0000685_abnormal_immune_system1.61340629
31MP0003656_abnormal_erythrocyte_physiolo1.59026672
32MP0009278_abnormal_bone_marrow1.58803684
33MP0005000_abnormal_immune_tolerance1.56548931
34MP0002723_abnormal_immune_serum1.53610495
35MP0005671_abnormal_response_to1.51170352
36MP0005397_hematopoietic_system_phenotyp1.50354944
37MP0001545_abnormal_hematopoietic_system1.50354944
38MP0002398_abnormal_bone_marrow1.47671651
39MP0000427_abnormal_hair_cycle1.43192724
40MP0002452_abnormal_antigen_presenting1.41933215
41MP0000015_abnormal_ear_pigmentation1.41318450
42MP0002419_abnormal_innate_immunity1.37067837
43MP0003111_abnormal_nucleus_morphology1.35395824
44MP0002095_abnormal_skin_pigmentation1.34893338
45MP0000689_abnormal_spleen_morphology1.33502597
46MP0002405_respiratory_system_inflammati1.32461694
47MP0005075_abnormal_melanosome_morpholog1.30784464
48MP0002420_abnormal_adaptive_immunity1.30493892
49MP0008775_abnormal_heart_ventricle1.29399466
50MP0001819_abnormal_immune_cell1.27244675
51MP0003186_abnormal_redox_activity1.22119816
52MP0000716_abnormal_immune_system1.21046838
53MP0002163_abnormal_gland_morphology1.20214692
54MP0003693_abnormal_embryo_hatching1.18739118
55MP0005174_abnormal_tail_pigmentation1.16863210
56MP0002148_abnormal_hypersensitivity_rea1.15857738
57MP0001348_abnormal_lacrimal_gland1.15721235
58MP0002166_altered_tumor_susceptibility1.14660087
59MP0008872_abnormal_physiological_respon1.11555907
60MP0002928_abnormal_bile_duct1.10888057
61MP0002429_abnormal_blood_cell1.09926871
62MP0002722_abnormal_immune_system1.09445487
63MP0001661_extended_life_span1.05268091
64MP0005025_abnormal_response_to1.03041181
65MP0005389_reproductive_system_phenotype1.02519537
66MP0009785_altered_susceptibility_to1.00724507
67MP0005387_immune_system_phenotype0.98624476
68MP0001790_abnormal_immune_system0.98624476
69MP0000465_gastrointestinal_hemorrhage0.98239164
70MP0005464_abnormal_platelet_physiology0.95844633
71MP0000703_abnormal_thymus_morphology0.94646475
72MP0004084_abnormal_cardiac_muscle0.89376418
73MP0003806_abnormal_nucleotide_metabolis0.87143536
74MP0002019_abnormal_tumor_incidence0.85824222
75MP0009764_decreased_sensitivity_to0.85433514
76MP0005451_abnormal_body_composition0.84544013
77MP0010307_abnormal_tumor_latency0.83952893
78MP0000313_abnormal_cell_death0.82658907
79MP0004147_increased_porphyrin_level0.82439834
80MP0001727_abnormal_embryo_implantation0.82395227
81MP0001845_abnormal_inflammatory_respons0.82075189
82MP0000371_diluted_coat_color0.80784688
83MP0004043_abnormal_pH_regulation0.78523176
84MP0002234_abnormal_pharynx_morphology0.78280340
85MP0002837_dystrophic_cardiac_calcinosis0.77760804
86MP0004808_abnormal_hematopoietic_stem0.76617307
87MP0001905_abnormal_dopamine_level0.76160055
88MP0009765_abnormal_xenobiotic_induced0.75785622
89MP0005220_abnormal_exocrine_pancreas0.75721658
90MP0008057_abnormal_DNA_replication0.74707883
91MP0003718_maternal_effect0.73949241
92MP0001968_abnormal_touch/_nociception0.72058850
93MP0002009_preneoplasia0.71498046
94MP0003252_abnormal_bile_duct0.71312906
95MP0004484_altered_response_of0.71140284
96MP0008469_abnormal_protein_level0.70578297
97MP0004883_abnormal_blood_vessel0.69646369
98MP0002006_tumorigenesis0.68788782
99MP0003077_abnormal_cell_cycle0.67974859
100MP0010386_abnormal_urinary_bladder0.67910783

Predicted human phenotypes

RankGene SetZ-score
1Abnormal delayed hypersensitivity skin test (HP:0002963)4.65602438
2Cutaneous melanoma (HP:0012056)4.48149534
3Increased IgM level (HP:0003496)4.11658865
4Autoimmune hemolytic anemia (HP:0001890)3.55703536
53-Methylglutaconic aciduria (HP:0003535)3.37926048
6Decreased central vision (HP:0007663)3.31377789
7Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.31131873
8Fatigue (HP:0012378)3.24930794
9Microvesicular hepatic steatosis (HP:0001414)3.09159097
10Retinal dysplasia (HP:0007973)2.97513001
11Abnormality of T cell physiology (HP:0011840)2.96402243
12Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.90633571
13Granulocytopenia (HP:0001913)2.88647122
14Abnormality of T cell number (HP:0011839)2.79914379
15Recurrent bacterial skin infections (HP:0005406)2.78208415
16Neurodegeneration (HP:0002180)2.77543562
17Testicular neoplasm (HP:0010788)2.70835059
18Abnormality of T cells (HP:0002843)2.70684623
19Abnormal mitochondria in muscle tissue (HP:0008316)2.56298668
20Impaired proprioception (HP:0010831)2.54704610
21Progressive macrocephaly (HP:0004481)2.54366397
22Small hand (HP:0200055)2.54338072
23Neoplasm of the adrenal cortex (HP:0100641)2.53138236
24Tubulointerstitial nephritis (HP:0001970)2.46984350
25Autoimmune thrombocytopenia (HP:0001973)2.46571681
26Acute necrotizing encephalopathy (HP:0006965)2.42471243
27IgM deficiency (HP:0002850)2.42393605
28Acute hepatic failure (HP:0006554)2.40139313
29Acanthocytosis (HP:0001927)2.39676317
30Panhypogammaglobulinemia (HP:0003139)2.39621831
31Gastrointestinal infarctions (HP:0005244)2.37795322
32Lipid accumulation in hepatocytes (HP:0006561)2.37747400
33Encephalitis (HP:0002383)2.36558234
34Abnormality of transition element cation homeostasis (HP:0011030)2.33271451
35Hyperthyroidism (HP:0000836)2.32244170
36Sandal gap (HP:0001852)2.31701426
37IgG deficiency (HP:0004315)2.31497385
38Eosinophilia (HP:0001880)2.29725963
39Agammaglobulinemia (HP:0004432)2.28593108
40Abnormal spermatogenesis (HP:0008669)2.28351572
41Increased muscle lipid content (HP:0009058)2.27379277
42Cone-rod dystrophy (HP:0000548)2.27170525
43Chronic obstructive pulmonary disease (HP:0006510)2.27036514
44Obstructive lung disease (HP:0006536)2.27036514
45Mitochondrial inheritance (HP:0001427)2.25261822
46Abnormality of iron homeostasis (HP:0011031)2.22840583
47Acute encephalopathy (HP:0006846)2.22642649
48Abnormality of the heme biosynthetic pathway (HP:0010472)2.22067779
49Gonadal dysgenesis (HP:0000133)2.21292664
50Hypoplastic pelvis (HP:0008839)2.20275143
51Mediastinal lymphadenopathy (HP:0100721)2.19632106
52Hypochromic anemia (HP:0001931)2.17646015
53Type II lissencephaly (HP:0007260)2.14357769
54Neutropenia (HP:0001875)2.12699343
55Thyroid-stimulating hormone excess (HP:0002925)2.11837376
56Recurrent abscess formation (HP:0002722)2.08506867
57Neoplasm of head and neck (HP:0012288)2.05260399
58Esophageal neoplasm (HP:0100751)2.05260399
59Arterial thrombosis (HP:0004420)2.04890309
60Thyroid carcinoma (HP:0002890)2.03886934
61Slow saccadic eye movements (HP:0000514)2.02569678
62Increased CSF lactate (HP:0002490)2.01918258
63Papillary thyroid carcinoma (HP:0002895)2.01804507
64Long clavicles (HP:0000890)2.00928057
65Ocular albinism (HP:0001107)2.00079601
66Squamous cell carcinoma (HP:0002860)2.00056460
67Leukocytosis (HP:0001974)1.99398958
68Aplastic anemia (HP:0001915)1.99211919
69Tinnitus (HP:0000360)1.97959263
70Macroorchidism (HP:0000053)1.95594174
71Hepatocellular necrosis (HP:0001404)1.95342422
72Pulmonary infiltrates (HP:0002113)1.95105115
73Increased serum pyruvate (HP:0003542)1.93307100
74Gaze-evoked nystagmus (HP:0000640)1.93248922
75Widely spaced teeth (HP:0000687)1.87354187
76Increased intramyocellular lipid droplets (HP:0012240)1.87202320
77Stomach cancer (HP:0012126)1.85595085
78Chromsome breakage (HP:0040012)1.85164132
79Long foot (HP:0001833)1.85133413
80Decreased electroretinogram (ERG) amplitude (HP:0000654)1.84588746
81Hepatic necrosis (HP:0002605)1.81700641
82Abnormality of eosinophils (HP:0001879)1.80718271
83Recurrent viral infections (HP:0004429)1.80379688
84Abnormality of cells of the lymphoid lineage (HP:0012140)1.80103010
85Chronic otitis media (HP:0000389)1.79031068
86Reticulocytopenia (HP:0001896)1.78019767
87Akinesia (HP:0002304)1.77548144
88Abnormality of dicarboxylic acid metabolism (HP:0010995)1.76581092
89Dicarboxylic aciduria (HP:0003215)1.76581092
90Congenital stationary night blindness (HP:0007642)1.76502445
91Absent rod-and cone-mediated responses on ERG (HP:0007688)1.76230990
92Melanoma (HP:0002861)1.76129230
93Duplicated collecting system (HP:0000081)1.75216750
94Abnormality of the renal collecting system (HP:0004742)1.74775209
95Cerebral hemorrhage (HP:0001342)1.73839165
96Birth length less than 3rd percentile (HP:0003561)1.73559782
97Gingival bleeding (HP:0000225)1.70989251
98Macrocytic anemia (HP:0001972)1.70666844
99Vasculitis (HP:0002633)1.69975766
100Myelodysplasia (HP:0002863)1.68705556

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NEK14.52306450
2FRK4.17508164
3MAP3K133.58670095
4RIPK43.17607535
5MAP3K142.96318467
6TESK22.90873751
7TAOK32.48862768
8PINK12.28553836
9PLK42.13726544
10FES2.09662169
11EIF2AK12.04755526
12MARK32.03636970
13CLK11.93671730
14MST41.90724827
15ZAK1.84825219
16TEC1.83569260
17PIK3CA1.81880336
18BTK1.77660982
19IKBKE1.77278759
20BCR1.74817920
21BMPR21.72861381
22VRK21.59654741
23NEK21.58328312
24ATR1.50766297
25ITK1.40651765
26JAK31.38775683
27SYK1.24365172
28BLK1.22493143
29PLK31.21366502
30NUAK11.19866693
31IKBKB1.19433827
32CHEK21.19266009
33TTK1.12914467
34FGFR21.08908492
35VRK11.04856430
36PBK1.04724619
37STK41.03282064
38PDK21.00865726
39MAP4K10.99970366
40STK110.98519918
41TRPM70.95158001
42MAP4K20.94956970
43CHUK0.94926602
44CDK90.92725816
45LYN0.88271478
46AKT30.87190591
47STK30.84672622
48TXK0.80184528
49BUB10.79713879
50WNK30.77703267
51ATM0.75013480
52CSF1R0.74656224
53RPS6KB20.73469933
54MAP2K70.72679391
55PIM10.71553059
56IRAK40.70471050
57TNIK0.69879351
58PLK10.69737840
59BMPR1B0.68330121
60CAMK1D0.67336759
61PRKCQ0.66699519
62IRAK10.66517242
63GRK60.66307856
64NME20.66058770
65LRRK20.64218415
66FGFR30.61365689
67CAMKK20.60146478
68BRSK20.60013146
69CSK0.59569170
70TSSK60.58273845
71MAPK130.58083575
72HCK0.57615713
73MAP3K70.57127293
74CDK30.53532749
75ERBB30.52507927
76MAP3K10.52475361
77FER0.51717511
78CHEK10.51250901
79JAK20.50162472
80AURKB0.49729715
81CSNK1D0.49641368
82BCKDK0.49596337
83TGFBR20.49483271
84EPHB10.49361748
85TLK10.49013039
86MAP3K120.48595991
87LCK0.48583923
88JAK10.47698710
89RPS6KA40.46730489
90CDK40.46309481
91RPS6KA50.45412926
92PAK30.44251482
93MATK0.43096023
94RAF10.40533738
95ADRBK20.39950795
96ABL10.39357222
97NME10.39315491
98CSNK2A20.37660088
99AKT10.36943462
100WNK10.36379540

Predicted pathways (KEGG)

RankGene SetZ-score
1Homologous recombination_Homo sapiens_hsa034403.89276881
2Base excision repair_Homo sapiens_hsa034103.45134871
3Fatty acid elongation_Homo sapiens_hsa000623.17123878
4Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.81251103
5Fanconi anemia pathway_Homo sapiens_hsa034602.66326538
6Non-homologous end-joining_Homo sapiens_hsa034502.62149802
7Sulfur metabolism_Homo sapiens_hsa009202.52574319
8DNA replication_Homo sapiens_hsa030302.49817313
9Mismatch repair_Homo sapiens_hsa034302.31669503
10SNARE interactions in vesicular transport_Homo sapiens_hsa041302.25469686
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.16702813
12NOD-like receptor signaling pathway_Homo sapiens_hsa046211.97123256
13RNA degradation_Homo sapiens_hsa030181.95228772
14Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.93392478
15Spliceosome_Homo sapiens_hsa030401.91248188
16Fatty acid metabolism_Homo sapiens_hsa012121.76368257
17RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.75621744
18NF-kappa B signaling pathway_Homo sapiens_hsa040641.74570011
19Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.65178915
20Oxidative phosphorylation_Homo sapiens_hsa001901.60873095
21mRNA surveillance pathway_Homo sapiens_hsa030151.55369983
22Basal transcription factors_Homo sapiens_hsa030221.48596188
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.46007374
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.45210608
25B cell receptor signaling pathway_Homo sapiens_hsa046621.40063303
26Parkinsons disease_Homo sapiens_hsa050121.39930279
27Measles_Homo sapiens_hsa051621.32563495
28Ribosome_Homo sapiens_hsa030101.29179601
29Herpes simplex infection_Homo sapiens_hsa051681.27037558
30p53 signaling pathway_Homo sapiens_hsa041151.26931570
31Nitrogen metabolism_Homo sapiens_hsa009101.26678726
32Phototransduction_Homo sapiens_hsa047441.25232775
33Selenocompound metabolism_Homo sapiens_hsa004501.22830657
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22039950
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.17252308
36Leishmaniasis_Homo sapiens_hsa051401.14537510
37Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.13759265
38Proteasome_Homo sapiens_hsa030501.13753908
39RNA polymerase_Homo sapiens_hsa030201.13122749
40Hepatitis B_Homo sapiens_hsa051611.10092685
41Primary immunodeficiency_Homo sapiens_hsa053401.08963704
42Nucleotide excision repair_Homo sapiens_hsa034201.07147742
43Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06204941
44Butanoate metabolism_Homo sapiens_hsa006501.04813525
45Peroxisome_Homo sapiens_hsa041461.01533939
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.98178850
47Toll-like receptor signaling pathway_Homo sapiens_hsa046200.97882583
48One carbon pool by folate_Homo sapiens_hsa006700.96413218
49Transcriptional misregulation in cancer_Homo sapiens_hsa052020.92771501
50Apoptosis_Homo sapiens_hsa042100.87789464
51Influenza A_Homo sapiens_hsa051640.83953694
52Pyrimidine metabolism_Homo sapiens_hsa002400.82821880
53Osteoclast differentiation_Homo sapiens_hsa043800.80400927
54RNA transport_Homo sapiens_hsa030130.78041703
55Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.77322149
56Cell cycle_Homo sapiens_hsa041100.77068835
57Graft-versus-host disease_Homo sapiens_hsa053320.73315629
58Purine metabolism_Homo sapiens_hsa002300.72413199
59Huntingtons disease_Homo sapiens_hsa050160.72191317
60Hepatitis C_Homo sapiens_hsa051600.71871902
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.71728380
62Asthma_Homo sapiens_hsa053100.70665334
63Autoimmune thyroid disease_Homo sapiens_hsa053200.70289543
64Primary bile acid biosynthesis_Homo sapiens_hsa001200.67542033
65Allograft rejection_Homo sapiens_hsa053300.63402632
66Alzheimers disease_Homo sapiens_hsa050100.61366171
67Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.61089816
68Pancreatic cancer_Homo sapiens_hsa052120.60757768
69Ether lipid metabolism_Homo sapiens_hsa005650.59826531
70Legionellosis_Homo sapiens_hsa051340.58600447
71Collecting duct acid secretion_Homo sapiens_hsa049660.57420521
72Olfactory transduction_Homo sapiens_hsa047400.55788151
73Vitamin digestion and absorption_Homo sapiens_hsa049770.55188927
74TNF signaling pathway_Homo sapiens_hsa046680.54766999
75Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52556698
76Tuberculosis_Homo sapiens_hsa051520.51604760
77Type I diabetes mellitus_Homo sapiens_hsa049400.50501050
78Propanoate metabolism_Homo sapiens_hsa006400.50218137
79Jak-STAT signaling pathway_Homo sapiens_hsa046300.48677441
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.48526480
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.47265699
82Non-small cell lung cancer_Homo sapiens_hsa052230.44702793
83Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43689818
84mTOR signaling pathway_Homo sapiens_hsa041500.42572418
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41536908
86Epstein-Barr virus infection_Homo sapiens_hsa051690.41338903
87Fatty acid degradation_Homo sapiens_hsa000710.40916588
88Fatty acid biosynthesis_Homo sapiens_hsa000610.40524378
89Systemic lupus erythematosus_Homo sapiens_hsa053220.39898452
90Adipocytokine signaling pathway_Homo sapiens_hsa049200.39652085
91Pyruvate metabolism_Homo sapiens_hsa006200.38154471
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.38092751
93Toxoplasmosis_Homo sapiens_hsa051450.37691971
94Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.36384808
95Intestinal immune network for IgA production_Homo sapiens_hsa046720.36234201
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.34551334
97Hematopoietic cell lineage_Homo sapiens_hsa046400.33586776
98Tryptophan metabolism_Homo sapiens_hsa003800.33341476
99Protein export_Homo sapiens_hsa030600.32076100
100Chronic myeloid leukemia_Homo sapiens_hsa052200.31738015

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