

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sensory perception of smell (GO:0007608) | 8.98740222 |
| 2 | epithelial cilium movement (GO:0003351) | 7.93410552 |
| 3 | nucleoside diphosphate phosphorylation (GO:0006165) | 7.53752662 |
| 4 | GTP biosynthetic process (GO:0006183) | 7.46972796 |
| 5 | ventricular system development (GO:0021591) | 7.22916092 |
| 6 | left/right axis specification (GO:0070986) | 7.20835940 |
| 7 | intraciliary transport (GO:0042073) | 7.14921054 |
| 8 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 6.78502730 |
| 9 | cilium or flagellum-dependent cell motility (GO:0001539) | 6.60386936 |
| 10 | UTP biosynthetic process (GO:0006228) | 6.57439947 |
| 11 | UTP metabolic process (GO:0046051) | 6.06367664 |
| 12 | microtubule bundle formation (GO:0001578) | 5.45868215 |
| 13 | sensory perception of chemical stimulus (GO:0007606) | 5.30872294 |
| 14 | protein insertion into membrane (GO:0051205) | 4.95259080 |
| 15 | guanosine-containing compound biosynthetic process (GO:1901070) | 4.92942182 |
| 16 | brain morphogenesis (GO:0048854) | 4.86910377 |
| 17 | cilium morphogenesis (GO:0060271) | 4.85311260 |
| 18 | CTP biosynthetic process (GO:0006241) | 4.79280783 |
| 19 | CTP metabolic process (GO:0046036) | 4.79280783 |
| 20 | behavioral response to nicotine (GO:0035095) | 4.71177487 |
| 21 | cilium organization (GO:0044782) | 4.39106494 |
| 22 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 4.31469495 |
| 23 | nucleotide phosphorylation (GO:0046939) | 4.19910397 |
| 24 | L-fucose catabolic process (GO:0042355) | 4.19637225 |
| 25 | fucose catabolic process (GO:0019317) | 4.19637225 |
| 26 | L-fucose metabolic process (GO:0042354) | 4.19637225 |
| 27 | cilium assembly (GO:0042384) | 4.18385984 |
| 28 | protein localization to cilium (GO:0061512) | 4.11685202 |
| 29 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 4.07288436 |
| 30 | negative regulation of inclusion body assembly (GO:0090084) | 4.01171338 |
| 31 | oxygen transport (GO:0015671) | 3.83052381 |
| 32 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 3.80615175 |
| 33 | regulation of cilium movement (GO:0003352) | 3.79425741 |
| 34 | multicellular organismal aging (GO:0010259) | 3.73333387 |
| 35 | cellular component assembly involved in morphogenesis (GO:0010927) | 3.72265744 |
| 36 | DNA deamination (GO:0045006) | 3.58003724 |
| 37 | response to histamine (GO:0034776) | 3.55887067 |
| 38 | microtubule-based movement (GO:0007018) | 3.55314491 |
| 39 | gas transport (GO:0015669) | 3.54858763 |
| 40 | nucleoside diphosphate metabolic process (GO:0009132) | 3.51619992 |
| 41 | left/right pattern formation (GO:0060972) | 3.50993335 |
| 42 | axon ensheathment in central nervous system (GO:0032291) | 3.50721726 |
| 43 | central nervous system myelination (GO:0022010) | 3.50721726 |
| 44 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.49713249 |
| 45 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.49224588 |
| 46 | regulation of macrophage chemotaxis (GO:0010758) | 3.49006743 |
| 47 | response to pheromone (GO:0019236) | 3.43093599 |
| 48 | cellular response to reactive nitrogen species (GO:1902170) | 3.43034277 |
| 49 | motile cilium assembly (GO:0044458) | 3.39831995 |
| 50 | response to xenobiotic stimulus (GO:0009410) | 3.26270360 |
| 51 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.22313380 |
| 52 | cornea development in camera-type eye (GO:0061303) | 3.21413332 |
| 53 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.18914932 |
| 54 | indole-containing compound catabolic process (GO:0042436) | 3.18686602 |
| 55 | indolalkylamine catabolic process (GO:0046218) | 3.18686602 |
| 56 | tryptophan catabolic process (GO:0006569) | 3.18686602 |
| 57 | cell projection assembly (GO:0030031) | 3.16929491 |
| 58 | piRNA metabolic process (GO:0034587) | 3.16150118 |
| 59 | reflex (GO:0060004) | 3.13480243 |
| 60 | amine catabolic process (GO:0009310) | 3.12176209 |
| 61 | cellular biogenic amine catabolic process (GO:0042402) | 3.12176209 |
| 62 | rRNA catabolic process (GO:0016075) | 3.11939383 |
| 63 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 3.10619806 |
| 64 | retinal cone cell development (GO:0046549) | 3.08244859 |
| 65 | positive regulation of cellular response to insulin stimulus (GO:1900078) | 3.08168572 |
| 66 | gamma-aminobutyric acid transport (GO:0015812) | 3.05685602 |
| 67 | chemical homeostasis within a tissue (GO:0048875) | 3.05537106 |
| 68 | exogenous drug catabolic process (GO:0042738) | 3.05406409 |
| 69 | kynurenine metabolic process (GO:0070189) | 3.05226230 |
| 70 | ubiquinone biosynthetic process (GO:0006744) | 3.04524023 |
| 71 | regulation of neurotransmitter uptake (GO:0051580) | 3.03349996 |
| 72 | indolalkylamine metabolic process (GO:0006586) | 3.02318376 |
| 73 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.02098553 |
| 74 | detection of light stimulus involved in visual perception (GO:0050908) | 3.02098553 |
| 75 | centriole replication (GO:0007099) | 3.00960802 |
| 76 | protein polyglutamylation (GO:0018095) | 2.98679989 |
| 77 | photoreceptor cell differentiation (GO:0046530) | 2.96618246 |
| 78 | eye photoreceptor cell differentiation (GO:0001754) | 2.96618246 |
| 79 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.94510443 |
| 80 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 2.94186640 |
| 81 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 2.94186640 |
| 82 | neuronal action potential (GO:0019228) | 2.93772878 |
| 83 | ER overload response (GO:0006983) | 2.91893387 |
| 84 | limb bud formation (GO:0060174) | 2.91610834 |
| 85 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.91429852 |
| 86 | auditory receptor cell stereocilium organization (GO:0060088) | 2.90350245 |
| 87 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.89168564 |
| 88 | nephron tubule morphogenesis (GO:0072078) | 2.86139531 |
| 89 | nephron epithelium morphogenesis (GO:0072088) | 2.86139531 |
| 90 | cellular ketone body metabolic process (GO:0046950) | 2.85795473 |
| 91 | multicellular organism reproduction (GO:0032504) | 2.85390683 |
| 92 | sperm motility (GO:0030317) | 2.85294944 |
| 93 | negative regulation of mast cell activation (GO:0033004) | 2.85257275 |
| 94 | centriole assembly (GO:0098534) | 2.81739474 |
| 95 | negative regulation of telomere maintenance (GO:0032205) | 2.80710151 |
| 96 | ubiquinone metabolic process (GO:0006743) | 2.80467233 |
| 97 | platelet dense granule organization (GO:0060155) | 2.79854959 |
| 98 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.78167367 |
| 99 | regulation of inclusion body assembly (GO:0090083) | 2.77073942 |
| 100 | detection of calcium ion (GO:0005513) | 2.74703169 |
| 101 | smoothened signaling pathway (GO:0007224) | 2.73924559 |
| 102 | ADP metabolic process (GO:0046031) | 2.73889172 |
| 103 | regulation of female gonad development (GO:2000194) | 2.73838955 |
| 104 | innate immune response in mucosa (GO:0002227) | 2.73488562 |
| 105 | atrial cardiac muscle cell action potential (GO:0086014) | 2.73198155 |
| 106 | drug catabolic process (GO:0042737) | 2.72909270 |
| 107 | tryptophan metabolic process (GO:0006568) | 2.71983296 |
| 108 | regulation of action potential (GO:0098900) | 2.69883024 |
| 109 | regulation of mononuclear cell migration (GO:0071675) | 2.68833797 |
| 110 | primary alcohol catabolic process (GO:0034310) | 2.68814459 |
| 111 | vitamin transmembrane transport (GO:0035461) | 2.67725180 |
| 112 | ketone body metabolic process (GO:1902224) | 2.64220037 |
| 113 | photoreceptor cell maintenance (GO:0045494) | 2.63784555 |
| 114 | positive regulation of fatty acid transport (GO:2000193) | 2.62784908 |
| 115 | regulation of hippo signaling (GO:0035330) | 2.61626507 |
| 116 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.60857556 |
| 117 | behavioral response to ethanol (GO:0048149) | 2.57943310 |
| 118 | regulation of collateral sprouting (GO:0048670) | 2.55267838 |
| 119 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.54753029 |
| 120 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.54534735 |
| 121 | surfactant homeostasis (GO:0043129) | 2.54453461 |
| 122 | DNA methylation involved in gamete generation (GO:0043046) | 2.53164774 |
| 123 | organic cation transport (GO:0015695) | 2.52243325 |
| 124 | neural tube formation (GO:0001841) | 2.52196712 |
| 125 | heart valve formation (GO:0003188) | 2.51871422 |
| 126 | negative regulation of astrocyte differentiation (GO:0048712) | 2.51558337 |
| 127 | aldehyde catabolic process (GO:0046185) | 2.51337313 |
| 128 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.50854364 |
| 129 | regulation of pigment cell differentiation (GO:0050932) | 2.50091682 |
| 130 | photoreceptor cell development (GO:0042461) | 2.47974960 |
| 131 | quinone biosynthetic process (GO:1901663) | 2.47387462 |
| 132 | female mating behavior (GO:0060180) | 2.47009947 |
| 133 | protein complex biogenesis (GO:0070271) | 2.46964939 |
| 134 | sulfation (GO:0051923) | 2.46207711 |
| 135 | phosphorelay signal transduction system (GO:0000160) | 2.45870007 |
| 136 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.45752755 |
| 137 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.45752755 |
| 138 | inner ear receptor stereocilium organization (GO:0060122) | 2.44850462 |
| 139 | primary amino compound metabolic process (GO:1901160) | 2.42281182 |
| 140 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 2.42272918 |
| 141 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.42129234 |
| 142 | protein-cofactor linkage (GO:0018065) | 2.41665478 |
| 143 | positive regulation of prostaglandin secretion (GO:0032308) | 2.41620682 |
| 144 | respiratory chain complex IV assembly (GO:0008535) | 2.41408969 |
| 145 | otic vesicle formation (GO:0030916) | 2.41404511 |
| 146 | indole-containing compound metabolic process (GO:0042430) | 2.40481859 |
| 147 | determination of left/right symmetry (GO:0007368) | 2.40219091 |
| 148 | cellular copper ion homeostasis (GO:0006878) | 2.39376305 |
| 149 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 2.38963049 |
| 150 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.36485672 |
| 151 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.36485672 |
| 152 | NADH dehydrogenase complex assembly (GO:0010257) | 2.36485672 |
| 153 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.36372294 |
| 154 | embryonic camera-type eye development (GO:0031076) | 2.35670552 |
| 155 | determination of bilateral symmetry (GO:0009855) | 2.31386855 |
| 156 | nonmotile primary cilium assembly (GO:0035058) | 2.30979121 |
| 157 | cellular response to nitric oxide (GO:0071732) | 2.30685440 |
| 158 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.30092220 |
| 159 | mucosal immune response (GO:0002385) | 2.29773606 |
| 160 | keratinocyte development (GO:0003334) | 2.28629234 |
| 161 | specification of symmetry (GO:0009799) | 2.28083872 |
| 162 | regulation of cell communication by electrical coupling (GO:0010649) | 2.28002908 |
| 163 | response to gravity (GO:0009629) | 2.27934031 |
| 164 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.26701549 |
| 165 | regulation of microtubule-based movement (GO:0060632) | 2.23989430 |
| 166 | one-carbon compound transport (GO:0019755) | 2.22900656 |
| 167 | L-ascorbic acid metabolic process (GO:0019852) | 2.22375222 |
| 168 | pyrimidine ribonucleotide metabolic process (GO:0009218) | 2.22303497 |
| 169 | regulation of toll-like receptor 4 signaling pathway (GO:0034143) | 2.21540719 |
| 170 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 2.19330018 |
| 171 | cerebral cortex neuron differentiation (GO:0021895) | 2.19077151 |
| 172 | axoneme assembly (GO:0035082) | 12.3124996 |
| 173 | cilium movement (GO:0003341) | 12.2050085 |
| 174 | axonemal dynein complex assembly (GO:0070286) | 10.0290802 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZNF274_21170338_ChIP-Seq_K562_Hela | 4.07499242 |
| 2 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.49927728 |
| 3 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.88180565 |
| 4 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.53314401 |
| 5 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.49907804 |
| 6 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.42004467 |
| 7 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.33942417 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.19629642 |
| 9 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.10272852 |
| 10 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.07330545 |
| 11 | GATA1_22025678_ChIP-Seq_K562_Human | 2.07156297 |
| 12 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.02956965 |
| 13 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.01244275 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.01181827 |
| 15 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.96362330 |
| 16 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.94771341 |
| 17 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.94767363 |
| 18 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.92858765 |
| 19 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.92105295 |
| 20 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.89908655 |
| 21 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.89908655 |
| 22 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.87582718 |
| 23 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.83392722 |
| 24 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.76958962 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.76603852 |
| 26 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.74475899 |
| 27 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.74463537 |
| 28 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.74458969 |
| 29 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.73957609 |
| 30 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.73262907 |
| 31 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.70880958 |
| 32 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.70354979 |
| 33 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.70066689 |
| 34 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.69605096 |
| 35 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.66786751 |
| 36 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.63918457 |
| 37 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.63771072 |
| 38 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.62380965 |
| 39 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.61852237 |
| 40 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.61606500 |
| 41 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.59829891 |
| 42 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.58534047 |
| 43 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.57625688 |
| 44 | FUS_26573619_Chip-Seq_HEK293_Human | 1.57018336 |
| 45 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.56815925 |
| 46 | P300_19829295_ChIP-Seq_ESCs_Human | 1.56027049 |
| 47 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.56000082 |
| 48 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.56000082 |
| 49 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.53563339 |
| 50 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.49802580 |
| 51 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.48757674 |
| 52 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.46606051 |
| 53 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.45954794 |
| 54 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.45954794 |
| 55 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.45343077 |
| 56 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.43465468 |
| 57 | TCF4_23295773_ChIP-Seq_U87_Human | 1.42776702 |
| 58 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.41703634 |
| 59 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.41340165 |
| 60 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40219237 |
| 61 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.39624168 |
| 62 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.39566992 |
| 63 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.38308697 |
| 64 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.38099404 |
| 65 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.35512303 |
| 66 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.35250471 |
| 67 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.33057598 |
| 68 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.30243059 |
| 69 | AR_20517297_ChIP-Seq_VCAP_Human | 1.30160367 |
| 70 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.29114606 |
| 71 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.29023213 |
| 72 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.28953416 |
| 73 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.28735756 |
| 74 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.28735756 |
| 75 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.28043571 |
| 76 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.26557946 |
| 77 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.26531306 |
| 78 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.26502676 |
| 79 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.24386940 |
| 80 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.24334802 |
| 81 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.23837584 |
| 82 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.23749540 |
| 83 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.23531757 |
| 84 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.23264064 |
| 85 | NCOR_22424771_ChIP-Seq_293T_Human | 1.22925870 |
| 86 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.21526194 |
| 87 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.21389162 |
| 88 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.21097182 |
| 89 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.19630676 |
| 90 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.18972182 |
| 91 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.18595608 |
| 92 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.18213704 |
| 93 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.18133025 |
| 94 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.17324253 |
| 95 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.17240578 |
| 96 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.16890602 |
| 97 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.16785748 |
| 98 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.16347353 |
| 99 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.16305210 |
| 100 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.15695224 |
| 101 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15692321 |
| 102 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.15559933 |
| 103 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.14734892 |
| 104 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.14712465 |
| 105 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.14507050 |
| 106 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.14182011 |
| 107 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13794787 |
| 108 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.13410927 |
| 109 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.10730754 |
| 110 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09888727 |
| 111 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.09888727 |
| 112 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09860534 |
| 113 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.09795119 |
| 114 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.08580896 |
| 115 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.08387235 |
| 116 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.06896663 |
| 117 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.06637679 |
| 118 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.04548105 |
| 119 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.04119794 |
| 120 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.03944460 |
| 121 | VDR_22108803_ChIP-Seq_LS180_Human | 1.01833461 |
| 122 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.01257107 |
| 123 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.00777157 |
| 124 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.00200263 |
| 125 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.00190968 |
| 126 | STAT3_23295773_ChIP-Seq_U87_Human | 0.99369207 |
| 127 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.99181983 |
| 128 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98616195 |
| 129 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.98500301 |
| 130 | ERA_21632823_ChIP-Seq_H3396_Human | 0.98481048 |
| 131 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.98113463 |
| 132 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.97926037 |
| 133 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.97518730 |
| 134 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.97479248 |
| 135 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.97081072 |
| 136 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.96513591 |
| 137 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.96387823 |
| 138 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.96173922 |
| 139 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.95994024 |
| 140 | AR_25329375_ChIP-Seq_VCAP_Human | 0.95958188 |
| 141 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.95700061 |
| 142 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.94802946 |
| 143 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.93631024 |
| 144 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.93517788 |
| 145 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.93466598 |
| 146 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.93429436 |
| 147 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92802297 |
| 148 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.92669699 |
| 149 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.90620416 |
| 150 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.90074867 |
| 151 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.89583325 |
| 152 | CJUN_26792858_Chip-Seq_BT549_Human | 0.89119495 |
| 153 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.86466629 |
| 154 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.85403672 |
| 155 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.84419281 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001984_abnormal_olfaction | 8.94259723 |
| 2 | MP0003136_yellow_coat_color | 4.83387691 |
| 3 | MP0002653_abnormal_ependyma_morphology | 3.82361356 |
| 4 | MP0005623_abnormal_meninges_morphology | 2.88911773 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.69635421 |
| 6 | MP0003195_calcinosis | 2.68818287 |
| 7 | MP0008875_abnormal_xenobiotic_pharmacok | 2.47426748 |
| 8 | MP0001958_emphysema | 2.41538625 |
| 9 | MP0004782_abnormal_surfactant_physiolog | 2.37299190 |
| 10 | MP0008995_early_reproductive_senescence | 2.35384227 |
| 11 | MP0002876_abnormal_thyroid_physiology | 2.32262045 |
| 12 | MP0004043_abnormal_pH_regulation | 2.24571727 |
| 13 | MP0008872_abnormal_physiological_respon | 2.17792902 |
| 14 | MP0000569_abnormal_digit_pigmentation | 2.13108139 |
| 15 | MP0004885_abnormal_endolymph | 2.11835574 |
| 16 | MP0005646_abnormal_pituitary_gland | 2.11102658 |
| 17 | MP0001968_abnormal_touch/_nociception | 2.04498610 |
| 18 | MP0002822_catalepsy | 2.03996817 |
| 19 | MP0001986_abnormal_taste_sensitivity | 2.02407674 |
| 20 | MP0005499_abnormal_olfactory_system | 1.99137833 |
| 21 | MP0005394_taste/olfaction_phenotype | 1.99137833 |
| 22 | MP0008789_abnormal_olfactory_epithelium | 1.94561174 |
| 23 | MP0004270_analgesia | 1.87406604 |
| 24 | MP0002132_abnormal_respiratory_system | 1.79609680 |
| 25 | MP0003787_abnormal_imprinting | 1.79254217 |
| 26 | MP0002160_abnormal_reproductive_system | 1.76938297 |
| 27 | MP0002249_abnormal_larynx_morphology | 1.73888146 |
| 28 | MP0002638_abnormal_pupillary_reflex | 1.72305550 |
| 29 | MP0002837_dystrophic_cardiac_calcinosis | 1.71430087 |
| 30 | MP0001485_abnormal_pinna_reflex | 1.71111450 |
| 31 | MP0005253_abnormal_eye_physiology | 1.68170590 |
| 32 | MP0002736_abnormal_nociception_after | 1.66903939 |
| 33 | MP0006072_abnormal_retinal_apoptosis | 1.66601128 |
| 34 | MP0003646_muscle_fatigue | 1.64939494 |
| 35 | MP0005388_respiratory_system_phenotype | 1.60566074 |
| 36 | MP0002133_abnormal_respiratory_system | 1.60566074 |
| 37 | MP0002184_abnormal_innervation | 1.59792451 |
| 38 | MP0004145_abnormal_muscle_electrophysio | 1.58541257 |
| 39 | MP0004742_abnormal_vestibular_system | 1.56955070 |
| 40 | MP0004147_increased_porphyrin_level | 1.53620887 |
| 41 | MP0002734_abnormal_mechanical_nocicepti | 1.51022354 |
| 42 | MP0004859_abnormal_synaptic_plasticity | 1.50314335 |
| 43 | MP0005377_hearing/vestibular/ear_phenot | 1.47790869 |
| 44 | MP0003878_abnormal_ear_physiology | 1.47790869 |
| 45 | MP0000383_abnormal_hair_follicle | 1.43563211 |
| 46 | MP0000778_abnormal_nervous_system | 1.43232487 |
| 47 | MP0002909_abnormal_adrenal_gland | 1.42436797 |
| 48 | MP0000427_abnormal_hair_cycle | 1.37432592 |
| 49 | MP0002272_abnormal_nervous_system | 1.36352290 |
| 50 | MP0001486_abnormal_startle_reflex | 1.35736635 |
| 51 | MP0006292_abnormal_olfactory_placode | 1.33510522 |
| 52 | MP0004133_heterotaxia | 1.30367685 |
| 53 | MP0003690_abnormal_glial_cell | 1.29975608 |
| 54 | MP0003634_abnormal_glial_cell | 1.28135218 |
| 55 | MP0002733_abnormal_thermal_nociception | 1.27785476 |
| 56 | MP0002282_abnormal_trachea_morphology | 1.25186816 |
| 57 | MP0003011_delayed_dark_adaptation | 1.23134998 |
| 58 | MP0003279_aneurysm | 1.22432694 |
| 59 | MP0002295_abnormal_pulmonary_circulatio | 1.22387520 |
| 60 | MP0003635_abnormal_synaptic_transmissio | 1.22062475 |
| 61 | MP0005083_abnormal_biliary_tract | 1.21439910 |
| 62 | MP0002557_abnormal_social/conspecific_i | 1.21164775 |
| 63 | MP0001502_abnormal_circadian_rhythm | 1.18309957 |
| 64 | MP0001440_abnormal_grooming_behavior | 1.17983297 |
| 65 | MP0002067_abnormal_sensory_capabilities | 1.17036333 |
| 66 | MP0002277_abnormal_respiratory_mucosa | 1.16464145 |
| 67 | MP0009780_abnormal_chondrocyte_physiolo | 1.15522482 |
| 68 | MP0001177_atelectasis | 1.13327132 |
| 69 | MP0002064_seizures | 1.13210315 |
| 70 | MP0001501_abnormal_sleep_pattern | 1.13198767 |
| 71 | MP0002233_abnormal_nose_morphology | 1.11676615 |
| 72 | MP0003950_abnormal_plasma_membrane | 1.09555161 |
| 73 | MP0005389_reproductive_system_phenotype | 1.08984063 |
| 74 | MP0001542_abnormal_bone_strength | 1.08948460 |
| 75 | MP0003075_altered_response_to | 1.07729014 |
| 76 | MP0009046_muscle_twitch | 1.07012079 |
| 77 | MP0003718_maternal_effect | 1.05943634 |
| 78 | MP0005167_abnormal_blood-brain_barrier | 1.05239790 |
| 79 | MP0000026_abnormal_inner_ear | 1.04249302 |
| 80 | MP0001851_eye_inflammation | 1.03996209 |
| 81 | MP0005551_abnormal_eye_electrophysiolog | 1.03642864 |
| 82 | MP0002735_abnormal_chemical_nociception | 1.03349854 |
| 83 | MP0004924_abnormal_behavior | 1.02645773 |
| 84 | MP0005386_behavior/neurological_phenoty | 1.02645773 |
| 85 | MP0009745_abnormal_behavioral_response | 1.01814706 |
| 86 | MP0003880_abnormal_central_pattern | 0.99961488 |
| 87 | MP0001529_abnormal_vocalization | 0.99729407 |
| 88 | MP0009384_cardiac_valve_regurgitation | 0.99078981 |
| 89 | MP0001879_abnormal_lymphatic_vessel | 0.97906293 |
| 90 | MP0003890_abnormal_embryonic-extraembry | 0.97857349 |
| 91 | MP0002254_reproductive_system_inflammat | 0.97776932 |
| 92 | MP0005174_abnormal_tail_pigmentation | 0.97642449 |
| 93 | MP0002928_abnormal_bile_duct | 0.97431203 |
| 94 | MP0000372_irregular_coat_pigmentation | 0.95552350 |
| 95 | MP0002063_abnormal_learning/memory/cond | 0.95026532 |
| 96 | MP0001324_abnormal_eye_pigmentation | 0.94365001 |
| 97 | MP0001905_abnormal_dopamine_level | 0.93254684 |
| 98 | MP0004858_abnormal_nervous_system | 0.93004168 |
| 99 | MP0005166_decreased_susceptibility_to | 0.92812554 |
| 100 | MP0003724_increased_susceptibility_to | 0.92403094 |
| 101 | MP0006276_abnormal_autonomic_nervous | 0.91830935 |
| 102 | MP0002572_abnormal_emotion/affect_behav | 0.91233487 |
| 103 | MP0001765_abnormal_ion_homeostasis | 0.91193875 |
| 104 | MP0000049_abnormal_middle_ear | 0.90737353 |
| 105 | MP0005410_abnormal_fertilization | 0.90305902 |
| 106 | MP0002752_abnormal_somatic_nervous | 0.89358597 |
| 107 | MP0005085_abnormal_gallbladder_physiolo | 0.89176366 |
| 108 | MP0003252_abnormal_bile_duct | 0.88702206 |
| 109 | MP0003806_abnormal_nucleotide_metabolis | 0.88452159 |
| 110 | MP0005636_abnormal_mineral_homeostasis | 0.88086433 |
| 111 | MP0003698_abnormal_male_reproductive | 0.87874629 |
| 112 | MP0004381_abnormal_hair_follicle | 0.87573833 |
| 113 | MP0002693_abnormal_pancreas_physiology | 0.87297290 |
| 114 | MP0003329_amyloid_beta_deposits | 0.87018414 |
| 115 | MP0002229_neurodegeneration | 0.86163512 |
| 116 | MP0001963_abnormal_hearing_physiology | 0.85956730 |
| 117 | MP0003283_abnormal_digestive_organ | 0.84791473 |
| 118 | MP0004484_altered_response_of | 0.84668817 |
| 119 | MP0000230_abnormal_systemic_arterial | 0.84512988 |
| 120 | MP0001970_abnormal_pain_threshold | 0.83927567 |
| 121 | MP0001929_abnormal_gametogenesis | 0.83568597 |
| 122 | MP0004142_abnormal_muscle_tone | 0.82648174 |
| 123 | MP0002938_white_spotting | 0.82077887 |
| 124 | MP0001919_abnormal_reproductive_system | 0.81550556 |
| 125 | MP0002882_abnormal_neuron_morphology | 0.81014893 |
| 126 | MP0005645_abnormal_hypothalamus_physiol | 0.79694722 |
| 127 | MP0005248_abnormal_Harderian_gland | 0.79320643 |
| 128 | MP0003937_abnormal_limbs/digits/tail_de | 0.78842426 |
| 129 | MP0002896_abnormal_bone_mineralization | 0.78804770 |
| 130 | MP0001340_abnormal_eyelid_morphology | 0.77427873 |
| 131 | MP0000920_abnormal_myelination | 0.77028442 |
| 132 | MP0001944_abnormal_pancreas_morphology | 0.76881057 |
| 133 | MP0005187_abnormal_penis_morphology | 0.76696310 |
| 134 | MP0001270_distended_abdomen | 0.74602300 |
| 135 | MP0002152_abnormal_brain_morphology | 0.74351562 |
| 136 | MP0005423_abnormal_somatic_nervous | 0.73921985 |
| 137 | MP0002163_abnormal_gland_morphology | 0.72726340 |
| 138 | MP0004215_abnormal_myocardial_fiber | 0.71933255 |
| 139 | MP0005165_increased_susceptibility_to | 0.69975503 |
| 140 | MP0009250_abnormal_appendicular_skeleto | 0.69913355 |
| 141 | MP0003938_abnormal_ear_development | 0.69128265 |
| 142 | MP0003942_abnormal_urinary_system | 0.68578798 |
| 143 | MP0003186_abnormal_redox_activity | 0.65704537 |
| 144 | MP0005084_abnormal_gallbladder_morpholo | 0.64102484 |
| 145 | MP0002092_abnormal_eye_morphology | 0.63567871 |
| 146 | MP0000631_abnormal_neuroendocrine_gland | 0.63352439 |
| 147 | MP0001293_anophthalmia | 0.62184960 |
| 148 | MP0003705_abnormal_hypodermis_morpholog | 0.61535192 |
| 149 | MP0008874_decreased_physiological_sensi | 0.61348391 |
| 150 | MP0005195_abnormal_posterior_eye | 0.60603331 |
| 151 | MP0003385_abnormal_body_wall | 0.60596645 |
| 152 | MP0004019_abnormal_vitamin_homeostasis | 0.59862091 |
| 153 | MP0002102_abnormal_ear_morphology | 0.59665888 |
| 154 | MP0005595_abnormal_vascular_smooth | 0.59632012 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal respiratory motile cilium morphology (HP:0005938) | 8.02697390 |
| 2 | Abnormal respiratory epithelium morphology (HP:0012253) | 8.02697390 |
| 3 | Chronic bronchitis (HP:0004469) | 6.93193287 |
| 4 | Bronchiectasis (HP:0002110) | 5.57317930 |
| 5 | Pancreatic fibrosis (HP:0100732) | 5.51846274 |
| 6 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.42995512 |
| 7 | Absent/shortened dynein arms (HP:0200106) | 4.42995512 |
| 8 | Median cleft lip (HP:0000161) | 4.19353110 |
| 9 | Chronic sinusitis (HP:0011109) | 4.10294077 |
| 10 | True hermaphroditism (HP:0010459) | 3.96210132 |
| 11 | Molar tooth sign on MRI (HP:0002419) | 3.49399881 |
| 12 | Abnormality of midbrain morphology (HP:0002418) | 3.49399881 |
| 13 | Bronchitis (HP:0012387) | 3.44896627 |
| 14 | Abnormality of dentin (HP:0010299) | 3.30886814 |
| 15 | Nasal polyposis (HP:0100582) | 3.20452371 |
| 16 | Congenital hepatic fibrosis (HP:0002612) | 3.16185240 |
| 17 | Recurrent sinusitis (HP:0011108) | 3.13384559 |
| 18 | Retinal dysplasia (HP:0007973) | 3.10153934 |
| 19 | Occipital encephalocele (HP:0002085) | 3.09918820 |
| 20 | Facial cleft (HP:0002006) | 3.07082767 |
| 21 | Tubular atrophy (HP:0000092) | 3.00391948 |
| 22 | Congenital stationary night blindness (HP:0007642) | 2.98920953 |
| 23 | Short nail (HP:0001799) | 2.98061061 |
| 24 | Abnormality of the nasal mucosa (HP:0000433) | 2.94911843 |
| 25 | Nephronophthisis (HP:0000090) | 2.89762569 |
| 26 | Postaxial foot polydactyly (HP:0001830) | 2.87485469 |
| 27 | Supernumerary spleens (HP:0009799) | 2.86820930 |
| 28 | Type II lissencephaly (HP:0007260) | 2.84456764 |
| 29 | Esophageal neoplasm (HP:0100751) | 2.83412915 |
| 30 | Neoplasm of head and neck (HP:0012288) | 2.83412915 |
| 31 | Hyperventilation (HP:0002883) | 2.79551859 |
| 32 | Pancreatic cysts (HP:0001737) | 2.78558596 |
| 33 | Abnormality of the renal cortex (HP:0011035) | 2.75749585 |
| 34 | Chronic hepatic failure (HP:0100626) | 2.70794905 |
| 35 | Gait imbalance (HP:0002141) | 2.70194020 |
| 36 | Congenital primary aphakia (HP:0007707) | 2.67309554 |
| 37 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.66090415 |
| 38 | Medial flaring of the eyebrow (HP:0010747) | 2.52145974 |
| 39 | Polydipsia (HP:0001959) | 2.51489322 |
| 40 | Abnormal drinking behavior (HP:0030082) | 2.51489322 |
| 41 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.49488982 |
| 42 | Postaxial hand polydactyly (HP:0001162) | 2.44615329 |
| 43 | Abnormality of the renal medulla (HP:0100957) | 2.40039284 |
| 44 | Cystic liver disease (HP:0006706) | 2.39438994 |
| 45 | Decreased circulating renin level (HP:0003351) | 2.39236945 |
| 46 | Preaxial hand polydactyly (HP:0001177) | 2.39057414 |
| 47 | Aplasia involving bones of the extremities (HP:0009825) | 2.36097625 |
| 48 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.36097625 |
| 49 | Aplasia of the phalanges of the hand (HP:0009802) | 2.36097625 |
| 50 | Decreased central vision (HP:0007663) | 2.31853894 |
| 51 | Nephrogenic diabetes insipidus (HP:0009806) | 2.31217699 |
| 52 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.28814472 |
| 53 | Large for gestational age (HP:0001520) | 2.28303723 |
| 54 | Abnormality of permanent molar morphology (HP:0011071) | 2.27514915 |
| 55 | Abnormality of the dental root (HP:0006486) | 2.27514915 |
| 56 | Taurodontia (HP:0000679) | 2.27514915 |
| 57 | Attenuation of retinal blood vessels (HP:0007843) | 2.24872037 |
| 58 | Bifid tongue (HP:0010297) | 2.24825300 |
| 59 | Genital tract atresia (HP:0001827) | 2.23186218 |
| 60 | Tubulointerstitial nephritis (HP:0001970) | 2.18897489 |
| 61 | Pendular nystagmus (HP:0012043) | 2.18784151 |
| 62 | Atelectasis (HP:0100750) | 2.15238453 |
| 63 | Vaginal atresia (HP:0000148) | 2.12989375 |
| 64 | Abnormality of molar (HP:0011077) | 2.12330225 |
| 65 | Abnormality of molar morphology (HP:0011070) | 2.12330225 |
| 66 | Recurrent otitis media (HP:0000403) | 2.12061358 |
| 67 | Cerebellar dysplasia (HP:0007033) | 2.11640114 |
| 68 | Gaze-evoked nystagmus (HP:0000640) | 2.09978711 |
| 69 | Asplenia (HP:0001746) | 2.05478151 |
| 70 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.03500578 |
| 71 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.02066894 |
| 72 | Absent speech (HP:0001344) | 2.01226495 |
| 73 | Pulmonary artery stenosis (HP:0004415) | 2.00696289 |
| 74 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 11.8423911 |
| 75 | Abnormal respiratory motile cilium physiology (HP:0012261) | 11.4245311 |
| 76 | Abnormal ciliary motility (HP:0012262) | 10.7467624 |
| 77 | Rhinitis (HP:0012384) | 10.7124025 |
| 78 | Abnormality of the dental pulp (HP:0006479) | 1.99903827 |
| 79 | Inability to walk (HP:0002540) | 1.99165668 |
| 80 | Polyuria (HP:0000103) | 1.98380015 |
| 81 | Short tibia (HP:0005736) | 1.94554830 |
| 82 | Congenital, generalized hypertrichosis (HP:0004540) | 1.94287072 |
| 83 | Increased corneal curvature (HP:0100692) | 1.94136397 |
| 84 | Keratoconus (HP:0000563) | 1.94136397 |
| 85 | Abnormality of macular pigmentation (HP:0008002) | 1.93198729 |
| 86 | Bile duct proliferation (HP:0001408) | 1.91011708 |
| 87 | Abnormal biliary tract physiology (HP:0012439) | 1.91011708 |
| 88 | Poor coordination (HP:0002370) | 1.89930934 |
| 89 | Constricted visual fields (HP:0001133) | 1.89749461 |
| 90 | Tubulointerstitial fibrosis (HP:0005576) | 1.87995721 |
| 91 | Broad-based gait (HP:0002136) | 1.87302391 |
| 92 | Tachypnea (HP:0002789) | 1.87233270 |
| 93 | Stage 5 chronic kidney disease (HP:0003774) | 1.87173809 |
| 94 | Male pseudohermaphroditism (HP:0000037) | 1.82349720 |
| 95 | Tubulointerstitial abnormality (HP:0001969) | 1.81813567 |
| 96 | Femoral bowing (HP:0002980) | 1.81525377 |
| 97 | Progressive cerebellar ataxia (HP:0002073) | 1.79187904 |
| 98 | Lissencephaly (HP:0001339) | 1.77100701 |
| 99 | Abolished electroretinogram (ERG) (HP:0000550) | 1.76016886 |
| 100 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.75806756 |
| 101 | Abnormality of alanine metabolism (HP:0010916) | 1.75806756 |
| 102 | Hyperalaninemia (HP:0003348) | 1.75806756 |
| 103 | Oculomotor apraxia (HP:0000657) | 1.72937323 |
| 104 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.72537223 |
| 105 | Retinitis pigmentosa (HP:0000510) | 1.72174818 |
| 106 | Homocystinuria (HP:0002156) | 1.71931770 |
| 107 | Abnormality of homocysteine metabolism (HP:0010919) | 1.71931770 |
| 108 | Omphalocele (HP:0001539) | 1.71235087 |
| 109 | Abnormality of renin-angiotensin system (HP:0000847) | 1.70744082 |
| 110 | Limb dystonia (HP:0002451) | 1.67163077 |
| 111 | Genetic anticipation (HP:0003743) | 1.65904482 |
| 112 | Sclerocornea (HP:0000647) | 1.65659384 |
| 113 | Bronchomalacia (HP:0002780) | 1.65248069 |
| 114 | Central scotoma (HP:0000603) | 1.62742416 |
| 115 | Aganglionic megacolon (HP:0002251) | 1.62570159 |
| 116 | Stomach cancer (HP:0012126) | 1.59242560 |
| 117 | Protruding tongue (HP:0010808) | 1.57781411 |
| 118 | Severe muscular hypotonia (HP:0006829) | 1.55910861 |
| 119 | Abnormal urine output (HP:0012590) | 1.55886956 |
| 120 | Onycholysis (HP:0001806) | 1.53835444 |
| 121 | Abnormality of renal excretion (HP:0011036) | 1.53240578 |
| 122 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.53155736 |
| 123 | Renal salt wasting (HP:0000127) | 1.53101944 |
| 124 | Multicystic kidney dysplasia (HP:0000003) | 1.52863402 |
| 125 | Renal cortical cysts (HP:0000803) | 1.52106498 |
| 126 | Anencephaly (HP:0002323) | 1.52084015 |
| 127 | Intellectual disability, moderate (HP:0002342) | 1.51959622 |
| 128 | Chronic otitis media (HP:0000389) | 1.51058921 |
| 129 | Ectopic anus (HP:0004397) | 1.50969811 |
| 130 | Progressive inability to walk (HP:0002505) | 1.50962348 |
| 131 | Hyperaldosteronism (HP:0000859) | 1.49979509 |
| 132 | Acute necrotizing encephalopathy (HP:0006965) | 1.49377740 |
| 133 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.49232321 |
| 134 | Syncope (HP:0001279) | 1.49202385 |
| 135 | Dandy-Walker malformation (HP:0001305) | 1.48959109 |
| 136 | Fibular aplasia (HP:0002990) | 1.46046219 |
| 137 | Myokymia (HP:0002411) | 1.45333680 |
| 138 | Furrowed tongue (HP:0000221) | 1.44508619 |
| 139 | Infertility (HP:0000789) | 1.43883208 |
| 140 | Neonatal short-limb short stature (HP:0008921) | 1.42774051 |
| 141 | Specific learning disability (HP:0001328) | 1.41506063 |
| 142 | Arterial tortuosity (HP:0005116) | 1.39803632 |
| 143 | Hyperactive renin-angiotensin system (HP:0000841) | 1.38584636 |
| 144 | Sex reversal (HP:0012245) | 1.38061287 |
| 145 | Abnormal sex determination (HP:0012244) | 1.38061287 |
| 146 | Nephropathy (HP:0000112) | 1.37756793 |
| 147 | Interstitial pulmonary disease (HP:0006530) | 1.37119819 |
| 148 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.35709888 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAPK15 | 7.86313091 |
| 2 | FRK | 4.84998827 |
| 3 | PNCK | 4.39890576 |
| 4 | MST4 | 3.25373131 |
| 5 | BMPR1B | 3.07898281 |
| 6 | SRPK1 | 2.89286490 |
| 7 | MAP2K2 | 2.58221259 |
| 8 | TLK1 | 2.53981074 |
| 9 | PHKG2 | 2.45187565 |
| 10 | PHKG1 | 2.45187565 |
| 11 | ACVR1B | 2.44826754 |
| 12 | ZAK | 2.43321054 |
| 13 | MAP4K2 | 2.39998691 |
| 14 | WNK4 | 2.34011815 |
| 15 | INSRR | 2.27903188 |
| 16 | CAMKK2 | 2.26843264 |
| 17 | PINK1 | 2.20254523 |
| 18 | DAPK2 | 2.11375230 |
| 19 | TAOK3 | 2.08167433 |
| 20 | NLK | 2.03453770 |
| 21 | WNK3 | 1.95943849 |
| 22 | TXK | 1.84045558 |
| 23 | RIPK1 | 1.65781831 |
| 24 | MAPK13 | 1.64549483 |
| 25 | GRK1 | 1.54124736 |
| 26 | CSNK1G1 | 1.51940504 |
| 27 | CAMK2B | 1.51862835 |
| 28 | ERBB3 | 1.44121538 |
| 29 | NUAK1 | 1.43116074 |
| 30 | MAP3K4 | 1.41307077 |
| 31 | PAK3 | 1.41294141 |
| 32 | MAP3K2 | 1.37588290 |
| 33 | DYRK1A | 1.35032034 |
| 34 | STK39 | 1.32968335 |
| 35 | CAMK2D | 1.30939710 |
| 36 | PLK2 | 1.30259906 |
| 37 | MAPKAPK3 | 1.28173086 |
| 38 | ROCK2 | 1.27513604 |
| 39 | ADRBK1 | 1.17689512 |
| 40 | AURKA | 1.16718924 |
| 41 | LMTK2 | 1.11857476 |
| 42 | DYRK2 | 1.11250695 |
| 43 | MELK | 1.04299637 |
| 44 | IRAK1 | 1.02361602 |
| 45 | TGFBR1 | 0.99955511 |
| 46 | CDK3 | 0.99651498 |
| 47 | NTRK2 | 0.97383178 |
| 48 | MYLK | 0.96733467 |
| 49 | TIE1 | 0.96493780 |
| 50 | MKNK2 | 0.95750063 |
| 51 | CAMK2G | 0.94156889 |
| 52 | STK24 | 0.93334297 |
| 53 | PRKCG | 0.93140137 |
| 54 | LRRK2 | 0.92188837 |
| 55 | BCKDK | 0.89962843 |
| 56 | TRIM28 | 0.89239858 |
| 57 | BCR | 0.85738818 |
| 58 | CSNK1G3 | 0.85541698 |
| 59 | CAMKK1 | 0.85448286 |
| 60 | CSNK1A1L | 0.84964377 |
| 61 | PTK2B | 0.81776562 |
| 62 | ILK | 0.81141286 |
| 63 | CASK | 0.81039936 |
| 64 | PIK3CA | 0.79846920 |
| 65 | MAPKAPK5 | 0.79808796 |
| 66 | VRK1 | 0.79682861 |
| 67 | AKT3 | 0.79673621 |
| 68 | PAK2 | 0.77895261 |
| 69 | JAK1 | 0.77159162 |
| 70 | ADRBK2 | 0.76655525 |
| 71 | ARAF | 0.75934475 |
| 72 | MAP2K7 | 0.73780529 |
| 73 | TSSK6 | 0.73602074 |
| 74 | RPS6KA2 | 0.73095617 |
| 75 | BRSK2 | 0.72770463 |
| 76 | AKT2 | 0.71555648 |
| 77 | CSNK1G2 | 0.71553217 |
| 78 | MAP2K6 | 0.69784955 |
| 79 | PKN1 | 0.69431641 |
| 80 | GSK3A | 0.69084544 |
| 81 | CDK19 | 0.68747716 |
| 82 | OXSR1 | 0.66335527 |
| 83 | MUSK | 0.63304787 |
| 84 | PRKCI | 0.62614274 |
| 85 | PDPK1 | 0.61069463 |
| 86 | SIK2 | 0.60889413 |
| 87 | FER | 0.60535980 |
| 88 | GRK5 | 0.59856220 |
| 89 | CAMK2A | 0.58576775 |
| 90 | HIPK2 | 0.57458601 |
| 91 | IKBKB | 0.56372595 |
| 92 | SGK223 | 0.56341459 |
| 93 | SGK494 | 0.56341459 |
| 94 | NTRK1 | 0.56226895 |
| 95 | MINK1 | 0.56172777 |
| 96 | PBK | 0.55418260 |
| 97 | NTRK3 | 0.52475647 |
| 98 | STK38L | 0.51241049 |
| 99 | CDK5 | 0.50938781 |
| 100 | SIK1 | 0.50902571 |
| 101 | MAPKAPK2 | 0.50521388 |
| 102 | PRKCE | 0.50062873 |
| 103 | RPS6KA5 | 0.49918801 |
| 104 | NEK2 | 0.49608886 |
| 105 | STK10 | 0.49468017 |
| 106 | ROCK1 | 0.49211882 |
| 107 | PRKCQ | 0.48817426 |
| 108 | CHUK | 0.47919241 |
| 109 | LIMK1 | 0.47792772 |
| 110 | KIT | 0.46959127 |
| 111 | BMPR2 | 0.46847739 |
| 112 | CAMK1 | 0.46771954 |
| 113 | NME1 | 0.45139069 |
| 114 | FGR | 0.45100783 |
| 115 | MAPK12 | 0.44791865 |
| 116 | TRPM7 | 0.43798899 |
| 117 | TNIK | 0.43357782 |
| 118 | EPHA4 | 0.43128856 |
| 119 | MAP2K1 | 0.42306917 |
| 120 | TGFBR2 | 0.42002747 |
| 121 | PRKCZ | 0.41924431 |
| 122 | MAPK9 | 0.41863333 |
| 123 | WEE1 | 0.41699745 |
| 124 | TNK2 | 0.41392242 |
| 125 | MAPK10 | 0.41350520 |
| 126 | EPHA3 | 0.41302338 |
| 127 | CSNK1A1 | 0.41270225 |
| 128 | GRK6 | 0.39711465 |
| 129 | TEC | 0.39090342 |
| 130 | PRKAA1 | 0.38136112 |
| 131 | GRK7 | 0.37954013 |
| 132 | PRKACA | 0.37898929 |
| 133 | PLK3 | 0.37573084 |
| 134 | MAP3K3 | 0.36470588 |
| 135 | MKNK1 | 0.36077117 |
| 136 | WNK1 | 0.35637697 |
| 137 | FYN | 0.35350314 |
| 138 | PRKCA | 0.35225291 |
| 139 | STK11 | 0.34940717 |
| 140 | TESK2 | 0.34735571 |
| 141 | MARK1 | 0.33961437 |
| 142 | MARK2 | 0.32602070 |
| 143 | CSNK1D | 0.32119376 |
| 144 | MAP3K7 | 0.31554732 |
| 145 | CAMK1G | 0.31453962 |
| 146 | PLK4 | 0.31393487 |
| 147 | FGFR2 | 0.31208640 |
| 148 | MAPK7 | 0.30017285 |
| 149 | IGF1R | 0.29926607 |
| 150 | SGK2 | 0.29433354 |
| 151 | CHEK2 | 0.29206389 |
| 152 | ERBB2 | 0.28672945 |
| 153 | PRKAA2 | 0.27876536 |
| 154 | ITK | 0.27578159 |
| 155 | PIK3CG | 0.27563853 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 7.28167294 |
| 2 | Histidine metabolism_Homo sapiens_hsa00340 | 2.95460225 |
| 3 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.86218362 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.82904262 |
| 5 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.78254091 |
| 6 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.45562708 |
| 7 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.43572742 |
| 8 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.31925929 |
| 9 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.29295331 |
| 10 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.24417000 |
| 11 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.99772105 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.99399271 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 1.88123388 |
| 14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.77550653 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 1.76226151 |
| 16 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.75759537 |
| 17 | Taste transduction_Homo sapiens_hsa04742 | 1.72100875 |
| 18 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.69150115 |
| 19 | Peroxisome_Homo sapiens_hsa04146 | 1.57299432 |
| 20 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.56167993 |
| 21 | GABAergic synapse_Homo sapiens_hsa04727 | 1.55147010 |
| 22 | Circadian entrainment_Homo sapiens_hsa04713 | 1.53123731 |
| 23 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.51756444 |
| 24 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.47626706 |
| 25 | Parkinsons disease_Homo sapiens_hsa05012 | 1.46525619 |
| 26 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.46286680 |
| 27 | Alzheimers disease_Homo sapiens_hsa05010 | 1.42310080 |
| 28 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.36952744 |
| 29 | Insulin secretion_Homo sapiens_hsa04911 | 1.32159855 |
| 30 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.28679980 |
| 31 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.25930080 |
| 32 | Morphine addiction_Homo sapiens_hsa05032 | 1.25175192 |
| 33 | Salivary secretion_Homo sapiens_hsa04970 | 1.25108415 |
| 34 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.25033018 |
| 35 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.24215308 |
| 36 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.22968844 |
| 37 | RNA polymerase_Homo sapiens_hsa03020 | 1.21849927 |
| 38 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.21425928 |
| 39 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.17951114 |
| 40 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.17446916 |
| 41 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.16881081 |
| 42 | Nicotine addiction_Homo sapiens_hsa05033 | 1.16610304 |
| 43 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.15942751 |
| 44 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.13122227 |
| 45 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.11067271 |
| 46 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.10135691 |
| 47 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.10067517 |
| 48 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.09574889 |
| 49 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.07372922 |
| 50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.06835276 |
| 51 | Bile secretion_Homo sapiens_hsa04976 | 1.06511843 |
| 52 | Protein export_Homo sapiens_hsa03060 | 1.04910179 |
| 53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.03938313 |
| 54 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.03227297 |
| 55 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.02743932 |
| 56 | Basal transcription factors_Homo sapiens_hsa03022 | 1.02545211 |
| 57 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.99897374 |
| 58 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.97223733 |
| 59 | Homologous recombination_Homo sapiens_hsa03440 | 0.95730845 |
| 60 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.94794296 |
| 61 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.94197910 |
| 62 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.89983970 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.88806735 |
| 64 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.88512136 |
| 65 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.88046632 |
| 66 | Axon guidance_Homo sapiens_hsa04360 | 0.85733393 |
| 67 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.85410132 |
| 68 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.84725703 |
| 69 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.83526150 |
| 70 | RNA degradation_Homo sapiens_hsa03018 | 0.82429876 |
| 71 | Cocaine addiction_Homo sapiens_hsa05030 | 0.79758307 |
| 72 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.78714829 |
| 73 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.78599895 |
| 74 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.77440814 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.76867292 |
| 76 | Asthma_Homo sapiens_hsa05310 | 0.76843245 |
| 77 | Long-term potentiation_Homo sapiens_hsa04720 | 0.76746033 |
| 78 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.75205465 |
| 79 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.74349701 |
| 80 | Renin secretion_Homo sapiens_hsa04924 | 0.74131373 |
| 81 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.73529843 |
| 82 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.72957496 |
| 83 | Circadian rhythm_Homo sapiens_hsa04710 | 0.72948521 |
| 84 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.72407593 |
| 85 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.70406132 |
| 86 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.68947623 |
| 87 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.68788331 |
| 88 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.68273539 |
| 89 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.67869831 |
| 90 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.67353689 |
| 91 | Melanogenesis_Homo sapiens_hsa04916 | 0.66857629 |
| 92 | Gap junction_Homo sapiens_hsa04540 | 0.65532766 |
| 93 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.64282465 |
| 94 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.63896273 |
| 95 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.63697476 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.63043128 |
| 97 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62433051 |
| 98 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.61834839 |
| 99 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.61718910 |
| 100 | ABC transporters_Homo sapiens_hsa02010 | 0.61043393 |
| 101 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.59367856 |
| 102 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.58369225 |
| 103 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.57693917 |
| 104 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.54626858 |
| 105 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.54494407 |
| 106 | Purine metabolism_Homo sapiens_hsa00230 | 0.54191018 |
| 107 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.53955799 |
| 108 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.51652099 |
| 109 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.50683621 |
| 110 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.47719544 |
| 111 | Mineral absorption_Homo sapiens_hsa04978 | 0.47149988 |
| 112 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.45276599 |
| 113 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.44849253 |
| 114 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.44128306 |
| 115 | Allograft rejection_Homo sapiens_hsa05330 | 0.43508859 |
| 116 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.42726086 |
| 117 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.42053296 |
| 118 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.42016512 |
| 119 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.41844758 |
| 120 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.41741530 |
| 121 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.41419995 |
| 122 | Tight junction_Homo sapiens_hsa04530 | 0.41395116 |
| 123 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.41084069 |
| 124 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.40964466 |
| 125 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.40554571 |
| 126 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.40451469 |
| 127 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.40362313 |
| 128 | Prion diseases_Homo sapiens_hsa05020 | 0.39357916 |
| 129 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.39253316 |
| 130 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.39221751 |
| 131 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.39153501 |
| 132 | Phagosome_Homo sapiens_hsa04145 | 0.38932069 |
| 133 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.38361923 |
| 134 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.37920735 |
| 135 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.37874521 |
| 136 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.37736816 |
| 137 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.37361886 |
| 138 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.36244058 |
| 139 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.35017315 |
| 140 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.34308844 |
| 141 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.34122516 |
| 142 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.32861866 |
| 143 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.32452581 |
| 144 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.31249282 |

