Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 4.96742369 |
2 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.93843762 |
3 | maturation of SSU-rRNA (GO:0030490) | 4.91964238 |
4 | DNA deamination (GO:0045006) | 4.72387669 |
5 | DNA strand elongation (GO:0022616) | 4.69516046 |
6 | viral transcription (GO:0019083) | 4.69233907 |
7 | nucleobase biosynthetic process (GO:0046112) | 4.66859091 |
8 | DNA replication initiation (GO:0006270) | 4.63981742 |
9 | translational termination (GO:0006415) | 4.60167967 |
10 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.58541269 |
11 | DNA unwinding involved in DNA replication (GO:0006268) | 4.58288214 |
12 | formation of translation preinitiation complex (GO:0001731) | 4.42328570 |
13 | purine nucleobase biosynthetic process (GO:0009113) | 4.38671207 |
14 | translational elongation (GO:0006414) | 4.32924631 |
15 | ribosomal large subunit biogenesis (GO:0042273) | 4.28970623 |
16 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.25803802 |
17 | * mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.23382816 |
18 | ribosomal small subunit biogenesis (GO:0042274) | 4.17556215 |
19 | translational initiation (GO:0006413) | 4.07040567 |
20 | DNA replication checkpoint (GO:0000076) | 4.05868450 |
21 | proteasome assembly (GO:0043248) | 4.02087363 |
22 | establishment of viral latency (GO:0019043) | 3.98539443 |
23 | telomere maintenance via recombination (GO:0000722) | 3.97304151 |
24 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.97238673 |
25 | chaperone-mediated protein transport (GO:0072321) | 3.97199610 |
26 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.90103985 |
27 | cotranslational protein targeting to membrane (GO:0006613) | 3.87682725 |
28 | protein targeting to ER (GO:0045047) | 3.85883257 |
29 | spliceosomal snRNP assembly (GO:0000387) | 3.83531248 |
30 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.81318658 |
31 | mitotic metaphase plate congression (GO:0007080) | 3.80576277 |
32 | establishment of integrated proviral latency (GO:0075713) | 3.77317277 |
33 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.75943868 |
34 | IMP biosynthetic process (GO:0006188) | 3.72709221 |
35 | protein localization to kinetochore (GO:0034501) | 3.72113734 |
36 | ribosome biogenesis (GO:0042254) | 3.72034364 |
37 | mitotic recombination (GO:0006312) | 3.71809311 |
38 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.67673447 |
39 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.67673447 |
40 | telomere maintenance via telomere lengthening (GO:0010833) | 3.66840658 |
41 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.65706193 |
42 | protein localization to endoplasmic reticulum (GO:0070972) | 3.64791913 |
43 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.64627304 |
44 | cellular protein complex disassembly (GO:0043624) | 3.64079159 |
45 | CENP-A containing nucleosome assembly (GO:0034080) | 3.62708834 |
46 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.62441776 |
47 | viral life cycle (GO:0019058) | 3.61838015 |
48 | chromatin remodeling at centromere (GO:0031055) | 3.61387898 |
49 | ribosome assembly (GO:0042255) | 3.59454882 |
50 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.57015570 |
51 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.55156236 |
52 | * energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.53558447 |
53 | * ATP synthesis coupled proton transport (GO:0015986) | 3.53558447 |
54 | rRNA processing (GO:0006364) | 3.49629908 |
55 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.49629527 |
56 | translation (GO:0006412) | 3.49022905 |
57 | folic acid metabolic process (GO:0046655) | 3.48602759 |
58 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.48302361 |
59 | protein targeting to mitochondrion (GO:0006626) | 3.46807676 |
60 | pseudouridine synthesis (GO:0001522) | 3.39373035 |
61 | oxidative phosphorylation (GO:0006119) | 3.39004084 |
62 | rRNA metabolic process (GO:0016072) | 3.36399694 |
63 | negative regulation of ligase activity (GO:0051352) | 3.33983535 |
64 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.33983535 |
65 | viral mRNA export from host cell nucleus (GO:0046784) | 3.33811051 |
66 | mitotic nuclear envelope disassembly (GO:0007077) | 3.33057064 |
67 | IMP metabolic process (GO:0046040) | 3.32435102 |
68 | metaphase plate congression (GO:0051310) | 3.30604719 |
69 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.29033297 |
70 | L-serine metabolic process (GO:0006563) | 3.28279576 |
71 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.27549682 |
72 | protein complex disassembly (GO:0043241) | 3.27497267 |
73 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.27011814 |
74 | spliceosomal complex assembly (GO:0000245) | 3.25416092 |
75 | cullin deneddylation (GO:0010388) | 3.23908364 |
76 | DNA replication-independent nucleosome organization (GO:0034724) | 3.22257679 |
77 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.22257679 |
78 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.20679420 |
79 | establishment of protein localization to mitochondrion (GO:0072655) | 3.18968135 |
80 | respiratory electron transport chain (GO:0022904) | 3.18308067 |
81 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.17562089 |
82 | protein deneddylation (GO:0000338) | 3.17041444 |
83 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.17040888 |
84 | cellular component biogenesis (GO:0044085) | 3.17027752 |
85 | termination of RNA polymerase III transcription (GO:0006386) | 3.14938835 |
86 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.14938835 |
87 | regulation of translational fidelity (GO:0006450) | 3.14877719 |
88 | macromolecular complex disassembly (GO:0032984) | 3.13657512 |
89 | protein localization to mitochondrion (GO:0070585) | 3.13372865 |
90 | protein maturation by protein folding (GO:0022417) | 3.12343025 |
91 | rRNA modification (GO:0000154) | 3.12302271 |
92 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.12251204 |
93 | protein localization to chromosome, centromeric region (GO:0071459) | 3.10389780 |
94 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.09341356 |
95 | electron transport chain (GO:0022900) | 3.08433460 |
96 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.08420589 |
97 | cell cycle G1/S phase transition (GO:0044843) | 3.08206907 |
98 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.08206907 |
99 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.06354616 |
100 | regulation of ligase activity (GO:0051340) | 3.04348356 |
101 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.03263223 |
102 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.02751354 |
103 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.02751354 |
104 | rRNA methylation (GO:0031167) | 3.02582188 |
105 | nuclear envelope disassembly (GO:0051081) | 3.02380281 |
106 | membrane disassembly (GO:0030397) | 3.02380281 |
107 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.00204727 |
108 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.00204727 |
109 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.00204727 |
110 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 3.00034402 |
111 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.99072147 |
112 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.98730072 |
113 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.98730072 |
114 | DNA ligation (GO:0006266) | 2.97266868 |
115 | positive regulation of ligase activity (GO:0051351) | 2.96349699 |
116 | mitotic sister chromatid segregation (GO:0000070) | 2.95139466 |
117 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.94990568 |
118 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.94884469 |
119 | DNA damage response, detection of DNA damage (GO:0042769) | 2.94430260 |
120 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.93780539 |
121 | histone exchange (GO:0043486) | 2.93046307 |
122 | regulation of mitochondrial translation (GO:0070129) | 2.92119866 |
123 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.91931135 |
124 | tetrahydrofolate metabolic process (GO:0046653) | 2.90900919 |
125 | establishment of chromosome localization (GO:0051303) | 2.89863120 |
126 | tRNA aminoacylation for protein translation (GO:0006418) | 2.89577512 |
127 | glycine metabolic process (GO:0006544) | 2.89206457 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.15488125 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.59669024 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.26528424 |
4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.61774526 |
5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.26163635 |
6 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.21771259 |
7 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.15249444 |
8 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.14478611 |
9 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.13631787 |
10 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.13175240 |
11 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.12635971 |
12 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.04541406 |
13 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.99649724 |
14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.89026800 |
15 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.80148354 |
16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.74480685 |
17 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.51494205 |
18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.49539404 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.41067192 |
20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.40277357 |
21 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.28108306 |
22 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.22670693 |
23 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.16506873 |
24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.10389234 |
25 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.03374663 |
26 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.03329003 |
27 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.01748589 |
28 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.00659616 |
29 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97911775 |
30 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.90248727 |
31 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.87919630 |
32 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.84678859 |
33 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.83961372 |
34 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.82126746 |
35 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.82120871 |
36 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.81597922 |
37 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.81174823 |
38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.78243301 |
39 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.71807420 |
40 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.71588620 |
41 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.70953198 |
42 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.67929389 |
43 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.67880600 |
44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.62436049 |
45 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.61492606 |
46 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57226824 |
47 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.57013927 |
48 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.51823717 |
49 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.50620982 |
50 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.49163821 |
51 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.44799276 |
52 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.43906742 |
53 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.43855079 |
54 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.42312324 |
55 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.42126220 |
56 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.38969698 |
57 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.38635719 |
58 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.35122783 |
59 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.33984491 |
60 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29552079 |
61 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.26184948 |
62 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.23268973 |
63 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.21541097 |
64 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.19849338 |
65 | MYC_22102868_ChIP-Seq_BL_Human | 1.18754674 |
66 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.17990578 |
67 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.17223845 |
68 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.17124246 |
69 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.16065797 |
70 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13826480 |
71 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.13331173 |
72 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.12289526 |
73 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.11454446 |
74 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.10035784 |
75 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.09905128 |
76 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09841542 |
77 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.09385945 |
78 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.06390096 |
79 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.05937711 |
80 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.04816915 |
81 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.04642021 |
82 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.04520352 |
83 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.04370330 |
84 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.02708782 |
85 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.01652024 |
86 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.99655688 |
87 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.99176726 |
88 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.97972085 |
89 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.97709376 |
90 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.96785877 |
91 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.96549624 |
92 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.96468530 |
93 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.96468164 |
94 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.96374340 |
95 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.95925955 |
96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.95033199 |
97 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.94887894 |
98 | * SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.94411314 |
99 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.92897414 |
100 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.92601619 |
101 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.89933924 |
102 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.89191555 |
103 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.88384501 |
104 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.87866571 |
105 | * PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.86167608 |
106 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.84277575 |
107 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.83750013 |
108 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.83011118 |
109 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.81817429 |
110 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.80167659 |
111 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.79527394 |
112 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.79525240 |
113 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.79466424 |
114 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.79406596 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.71564921 |
2 | MP0004957_abnormal_blastocyst_morpholog | 4.78758322 |
3 | MP0010094_abnormal_chromosome_stability | 4.54614526 |
4 | MP0003111_abnormal_nucleus_morphology | 4.46047036 |
5 | MP0003077_abnormal_cell_cycle | 4.04960318 |
6 | MP0003806_abnormal_nucleotide_metabolis | 3.81597837 |
7 | MP0008058_abnormal_DNA_repair | 3.46360436 |
8 | MP0008057_abnormal_DNA_replication | 3.25633464 |
9 | MP0008932_abnormal_embryonic_tissue | 2.98745104 |
10 | MP0008007_abnormal_cellular_replicative | 2.76543449 |
11 | MP0003123_paternal_imprinting | 2.47771832 |
12 | MP0001730_embryonic_growth_arrest | 2.47629703 |
13 | MP0000350_abnormal_cell_proliferation | 2.07765999 |
14 | MP0003718_maternal_effect | 1.97479340 |
15 | MP0003186_abnormal_redox_activity | 1.96146617 |
16 | MP0006036_abnormal_mitochondrial_physio | 1.84840690 |
17 | MP0002396_abnormal_hematopoietic_system | 1.80315160 |
18 | MP0001697_abnormal_embryo_size | 1.76862855 |
19 | MP0003786_premature_aging | 1.72236962 |
20 | MP0001672_abnormal_embryogenesis/_devel | 1.70718694 |
21 | MP0005380_embryogenesis_phenotype | 1.70718694 |
22 | MP0002080_prenatal_lethality | 1.68053177 |
23 | MP0010030_abnormal_orbit_morphology | 1.60068435 |
24 | MP0005451_abnormal_body_composition | 1.55782027 |
25 | MP0006035_abnormal_mitochondrial_morpho | 1.55557059 |
26 | MP0003984_embryonic_growth_retardation | 1.51782756 |
27 | MP0000490_abnormal_crypts_of | 1.50189842 |
28 | MP0009379_abnormal_foot_pigmentation | 1.50021973 |
29 | MP0002088_abnormal_embryonic_growth/wei | 1.48326453 |
30 | MP0004133_heterotaxia | 1.47688490 |
31 | MP0000313_abnormal_cell_death | 1.44674113 |
32 | MP0010352_gastrointestinal_tract_polyps | 1.44239647 |
33 | MP0002085_abnormal_embryonic_tissue | 1.44186202 |
34 | MP0008877_abnormal_DNA_methylation | 1.41854523 |
35 | MP0002019_abnormal_tumor_incidence | 1.37378174 |
36 | MP0003567_abnormal_fetal_cardiomyocyte | 1.35219829 |
37 | MP0003315_abnormal_perineum_morphology | 1.34292640 |
38 | MP0000358_abnormal_cell_content/ | 1.30985760 |
39 | MP0002938_white_spotting | 1.29831522 |
40 | MP0002084_abnormal_developmental_patter | 1.26090808 |
41 | MP0001346_abnormal_lacrimal_gland | 1.25084950 |
42 | MP0010307_abnormal_tumor_latency | 1.23304508 |
43 | MP0000537_abnormal_urethra_morphology | 1.21864091 |
44 | MP0002086_abnormal_extraembryonic_tissu | 1.20243173 |
45 | MP0008789_abnormal_olfactory_epithelium | 1.19597771 |
46 | MP0003119_abnormal_digestive_system | 1.18266940 |
47 | MP0002160_abnormal_reproductive_system | 1.17339970 |
48 | MP0009053_abnormal_anal_canal | 1.17183848 |
49 | MP0004197_abnormal_fetal_growth/weight/ | 1.15895154 |
50 | MP0002132_abnormal_respiratory_system | 1.15792577 |
51 | MP0001661_extended_life_span | 1.14442175 |
52 | MP0005410_abnormal_fertilization | 1.11718343 |
53 | MP0009333_abnormal_splenocyte_physiolog | 1.10568703 |
54 | MP0001529_abnormal_vocalization | 1.10384966 |
55 | MP0001764_abnormal_homeostasis | 1.09502820 |
56 | MP0002234_abnormal_pharynx_morphology | 1.09492185 |
57 | MP0000678_abnormal_parathyroid_gland | 1.08006150 |
58 | MP0001293_anophthalmia | 1.07428266 |
59 | MP0004233_abnormal_muscle_weight | 1.05377448 |
60 | MP0002139_abnormal_hepatobiliary_system | 1.05223439 |
61 | MP0005266_abnormal_metabolism | 1.05184194 |
62 | MP0003890_abnormal_embryonic-extraembry | 1.04504926 |
63 | MP0002796_impaired_skin_barrier | 1.02609560 |
64 | MP0003221_abnormal_cardiomyocyte_apopto | 1.01429430 |
65 | MP0002210_abnormal_sex_determination | 0.99798664 |
66 | MP0009672_abnormal_birth_weight | 0.98471610 |
67 | MP0000049_abnormal_middle_ear | 0.96923198 |
68 | MP0000749_muscle_degeneration | 0.96223557 |
69 | MP0003646_muscle_fatigue | 0.96122382 |
70 | MP0005408_hypopigmentation | 0.92801003 |
71 | MP0001145_abnormal_male_reproductive | 0.92782332 |
72 | MP0008260_abnormal_autophagy | 0.92566748 |
73 | MP0003656_abnormal_erythrocyte_physiolo | 0.91713710 |
74 | MP0002697_abnormal_eye_size | 0.90948295 |
75 | MP0004147_increased_porphyrin_level | 0.90696277 |
76 | MP0005360_urolithiasis | 0.90643610 |
77 | MP0000566_synostosis | 0.90118285 |
78 | MP0000762_abnormal_tongue_morphology | 0.89549508 |
79 | MP0005389_reproductive_system_phenotype | 0.86983963 |
80 | MP0001853_heart_inflammation | 0.85247485 |
81 | MP0009840_abnormal_foam_cell | 0.85226580 |
82 | MP0000750_abnormal_muscle_regeneration | 0.85180569 |
83 | MP0002111_abnormal_tail_morphology | 0.84922996 |
84 | MP0005085_abnormal_gallbladder_physiolo | 0.83653333 |
85 | MP0000751_myopathy | 0.83071582 |
86 | MP0003937_abnormal_limbs/digits/tail_de | 0.82937605 |
87 | MP0001881_abnormal_mammary_gland | 0.80877800 |
88 | MP0001727_abnormal_embryo_implantation | 0.79655399 |
89 | MP0000858_altered_metastatic_potential | 0.78306595 |
90 | MP0005670_abnormal_white_adipose | 0.77549490 |
91 | MP0000653_abnormal_sex_gland | 0.77023260 |
92 | MP0005499_abnormal_olfactory_system | 0.76835390 |
93 | MP0005394_taste/olfaction_phenotype | 0.76835390 |
94 | MP0008995_early_reproductive_senescence | 0.75893582 |
95 | MP0006054_spinal_hemorrhage | 0.74915993 |
96 | MP0004808_abnormal_hematopoietic_stem | 0.74905400 |
97 | MP0003121_genomic_imprinting | 0.74865505 |
98 | MP0000372_irregular_coat_pigmentation | 0.74571386 |
99 | MP0006292_abnormal_olfactory_placode | 0.74361471 |
100 | MP0002653_abnormal_ependyma_morphology | 0.74015696 |
101 | MP0005332_abnormal_amino_acid | 0.73519436 |
102 | MP0001119_abnormal_female_reproductive | 0.73294642 |
103 | MP0002269_muscular_atrophy | 0.73157840 |
104 | MP0002163_abnormal_gland_morphology | 0.72843742 |
105 | MP0001286_abnormal_eye_development | 0.72440734 |
106 | MP0002233_abnormal_nose_morphology | 0.72214478 |
107 | MP0000598_abnormal_liver_morphology | 0.72121579 |
108 | MP0005384_cellular_phenotype | 0.71510932 |
109 | MP0000703_abnormal_thymus_morphology | 0.71455632 |
110 | MP0005501_abnormal_skin_physiology | 0.71217421 |
111 | MP0002877_abnormal_melanocyte_morpholog | 0.71169995 |
112 | MP0005623_abnormal_meninges_morphology | 0.71097411 |
113 | MP0002722_abnormal_immune_system | 0.69870117 |
114 | MP0005397_hematopoietic_system_phenotyp | 0.69160156 |
115 | MP0001545_abnormal_hematopoietic_system | 0.69160156 |
116 | MP0001929_abnormal_gametogenesis | 0.68529266 |
117 | MP0005395_other_phenotype | 0.67313660 |
118 | MP0003698_abnormal_male_reproductive | 0.67306385 |
119 | MP0002102_abnormal_ear_morphology | 0.66673270 |
120 | MP0005319_abnormal_enzyme/_coenzyme | 0.66650487 |
121 | MP0002161_abnormal_fertility/fecundity | 0.66503084 |
122 | MP0004272_abnormal_basement_membrane | 0.66474235 |
123 | MP0000689_abnormal_spleen_morphology | 0.66057120 |
124 | MP0003941_abnormal_skin_development | 0.65359127 |
125 | MP0005075_abnormal_melanosome_morpholog | 0.62229564 |
126 | MP0004084_abnormal_cardiac_muscle | 0.60814720 |
127 | MP0005023_abnormal_wound_healing | 0.59092352 |
128 | MP0009697_abnormal_copulation | 0.58722362 |
129 | MP0000467_abnormal_esophagus_morphology | 0.58365327 |
130 | MP0000477_abnormal_intestine_morphology | 0.58035684 |
131 | MP0004185_abnormal_adipocyte_glucose | 0.56980293 |
132 | MP0001919_abnormal_reproductive_system | 0.56943727 |
133 | MP0005365_abnormal_bile_salt | 0.56728064 |
134 | MP0005330_cardiomyopathy | 0.56311116 |
135 | MP0001915_intracranial_hemorrhage | 0.55947897 |
136 | MP0003763_abnormal_thymus_physiology | 0.55650359 |
137 | MP0001849_ear_inflammation | 0.55335615 |
138 | MP0003011_delayed_dark_adaptation | 0.54774100 |
139 | MP0005376_homeostasis/metabolism_phenot | 0.54453721 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.01747423 |
2 | Reticulocytopenia (HP:0001896) | 4.78693763 |
3 | Abnormal number of erythroid precursors (HP:0012131) | 4.64588148 |
4 | Birth length less than 3rd percentile (HP:0003561) | 4.60533320 |
5 | Oral leukoplakia (HP:0002745) | 4.24469645 |
6 | Breast hypoplasia (HP:0003187) | 3.86883883 |
7 | Macrocytic anemia (HP:0001972) | 3.66164269 |
8 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.43457543 |
9 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.43457543 |
10 | Cerebral hypomyelination (HP:0006808) | 3.34335998 |
11 | Hepatocellular necrosis (HP:0001404) | 3.33963917 |
12 | Colon cancer (HP:0003003) | 3.33668069 |
13 | Hepatic necrosis (HP:0002605) | 3.26472279 |
14 | Increased serum lactate (HP:0002151) | 3.23042783 |
15 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.14764127 |
16 | Type I transferrin isoform profile (HP:0003642) | 3.09473161 |
17 | Abnormality of glycolysis (HP:0004366) | 3.06995126 |
18 | Increased serum pyruvate (HP:0003542) | 3.06995126 |
19 | Pallor (HP:0000980) | 3.02973804 |
20 | Rough bone trabeculation (HP:0100670) | 3.02833098 |
21 | Abnormality of the anterior horn cell (HP:0006802) | 3.00363118 |
22 | Degeneration of anterior horn cells (HP:0002398) | 3.00363118 |
23 | Multiple enchondromatosis (HP:0005701) | 2.98048453 |
24 | Renal Fanconi syndrome (HP:0001994) | 2.96964702 |
25 | Increased CSF lactate (HP:0002490) | 2.95968300 |
26 | Mitochondrial inheritance (HP:0001427) | 2.92194815 |
27 | Selective tooth agenesis (HP:0001592) | 2.91045552 |
28 | Carpal bone hypoplasia (HP:0001498) | 2.90133297 |
29 | Acute necrotizing encephalopathy (HP:0006965) | 2.88831803 |
30 | Aplastic anemia (HP:0001915) | 2.87522106 |
31 | Patellar aplasia (HP:0006443) | 2.81968969 |
32 | Ependymoma (HP:0002888) | 2.79234786 |
33 | Reduced antithrombin III activity (HP:0001976) | 2.78692572 |
34 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.75508243 |
35 | Microretrognathia (HP:0000308) | 2.73490885 |
36 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.69393165 |
37 | Testicular atrophy (HP:0000029) | 2.67789966 |
38 | Absent thumb (HP:0009777) | 2.64337413 |
39 | Trismus (HP:0000211) | 2.63712633 |
40 | Acute encephalopathy (HP:0006846) | 2.61106713 |
41 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.54021130 |
42 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.53899467 |
43 | Lactic acidosis (HP:0003128) | 2.49821937 |
44 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.46838452 |
45 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.46838452 |
46 | Abnormal protein glycosylation (HP:0012346) | 2.46838452 |
47 | Abnormal glycosylation (HP:0012345) | 2.46838452 |
48 | Secondary amenorrhea (HP:0000869) | 2.44281849 |
49 | Lipid accumulation in hepatocytes (HP:0006561) | 2.42638745 |
50 | Increased hepatocellular lipid droplets (HP:0006565) | 2.41679535 |
51 | Ragged-red muscle fibers (HP:0003200) | 2.38297319 |
52 | Abnormality of reticulocytes (HP:0004312) | 2.37809436 |
53 | Neoplasm of the pancreas (HP:0002894) | 2.37479973 |
54 | Megaloblastic anemia (HP:0001889) | 2.36719276 |
55 | Facial cleft (HP:0002006) | 2.36042929 |
56 | Medulloblastoma (HP:0002885) | 2.35755288 |
57 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.35636942 |
58 | Meckel diverticulum (HP:0002245) | 2.33862457 |
59 | Cellular immunodeficiency (HP:0005374) | 2.31851155 |
60 | Cerebral edema (HP:0002181) | 2.31725903 |
61 | Abnormality of the preputium (HP:0100587) | 2.30678893 |
62 | Nausea (HP:0002018) | 2.28392300 |
63 | Microvesicular hepatic steatosis (HP:0001414) | 2.27762577 |
64 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.27584287 |
65 | Abnormality of alanine metabolism (HP:0010916) | 2.27584287 |
66 | Hyperalaninemia (HP:0003348) | 2.27584287 |
67 | Premature ovarian failure (HP:0008209) | 2.26553996 |
68 | 11 pairs of ribs (HP:0000878) | 2.24259083 |
69 | Agnosia (HP:0010524) | 2.24181512 |
70 | Gout (HP:0001997) | 2.23997161 |
71 | Horseshoe kidney (HP:0000085) | 2.23784334 |
72 | 3-Methylglutaconic aciduria (HP:0003535) | 2.22903145 |
73 | Abnormality of the ileum (HP:0001549) | 2.22880265 |
74 | Absent radius (HP:0003974) | 2.22563414 |
75 | CNS demyelination (HP:0007305) | 2.21779453 |
76 | Pancytopenia (HP:0001876) | 2.21529931 |
77 | Exercise intolerance (HP:0003546) | 2.21372976 |
78 | Sparse eyelashes (HP:0000653) | 2.20295122 |
79 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.20140766 |
80 | Premature graying of hair (HP:0002216) | 2.19394867 |
81 | Abnormality of methionine metabolism (HP:0010901) | 2.19036471 |
82 | Rhabdomyosarcoma (HP:0002859) | 2.18939098 |
83 | Abnormal gallbladder physiology (HP:0012438) | 2.18390825 |
84 | Cholecystitis (HP:0001082) | 2.18390825 |
85 | Abnormal number of incisors (HP:0011064) | 2.16975258 |
86 | Generalized aminoaciduria (HP:0002909) | 2.16376503 |
87 | Leukodystrophy (HP:0002415) | 2.15260538 |
88 | Thrombocytosis (HP:0001894) | 2.12611448 |
89 | Chromsome breakage (HP:0040012) | 2.12187315 |
90 | Abnormal trabecular bone morphology (HP:0100671) | 2.12157876 |
91 | Abnormality of the umbilical cord (HP:0010881) | 2.11082034 |
92 | Respiratory failure (HP:0002878) | 2.10495782 |
93 | Adenoma sebaceum (HP:0009720) | 2.10396140 |
94 | Angiofibromas (HP:0010615) | 2.10396140 |
95 | Bone marrow hypocellularity (HP:0005528) | 2.09335772 |
96 | Emotional lability (HP:0000712) | 2.08140353 |
97 | Hypobetalipoproteinemia (HP:0003563) | 2.07664224 |
98 | Rhabdomyolysis (HP:0003201) | 2.07331584 |
99 | Progressive macrocephaly (HP:0004481) | 2.05564846 |
100 | Progressive muscle weakness (HP:0003323) | 2.05039500 |
101 | Increased intramyocellular lipid droplets (HP:0012240) | 2.03634351 |
102 | Aplasia involving forearm bones (HP:0009822) | 2.03115657 |
103 | Absent forearm bone (HP:0003953) | 2.03115657 |
104 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.00853405 |
105 | Abnormality of chromosome stability (HP:0003220) | 1.98265268 |
106 | Hyperglycinemia (HP:0002154) | 1.97162796 |
107 | Increased muscle lipid content (HP:0009058) | 1.93885895 |
108 | Triphalangeal thumb (HP:0001199) | 1.93548849 |
109 | Lethargy (HP:0001254) | 1.93342330 |
110 | Supernumerary spleens (HP:0009799) | 1.92928844 |
111 | Abnormality of serum amino acid levels (HP:0003112) | 1.91150317 |
112 | Abnormal lung lobation (HP:0002101) | 1.89483188 |
113 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.89218211 |
114 | Myelodysplasia (HP:0002863) | 1.89117553 |
115 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.88749081 |
116 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.88484119 |
117 | Glossoptosis (HP:0000162) | 1.88426748 |
118 | Respiratory difficulties (HP:0002880) | 1.87687680 |
119 | CNS hypomyelination (HP:0003429) | 1.87201252 |
120 | Hypoplastic pelvis (HP:0008839) | 1.86536076 |
121 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.81020315 |
122 | Single umbilical artery (HP:0001195) | 1.81020315 |
123 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.81020315 |
124 | Cleft eyelid (HP:0000625) | 1.80467279 |
125 | Dicarboxylic aciduria (HP:0003215) | 1.79712229 |
126 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.79712229 |
127 | Exertional dyspnea (HP:0002875) | 1.78097557 |
128 | Opisthotonus (HP:0002179) | 1.75677338 |
129 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.73768409 |
130 | Abnormality of placental membranes (HP:0011409) | 1.69918864 |
131 | Amniotic constriction ring (HP:0009775) | 1.69918864 |
132 | Optic disc pallor (HP:0000543) | 1.69067584 |
133 | Redundant skin (HP:0001582) | 1.67058545 |
134 | Small intestinal stenosis (HP:0012848) | 1.64347798 |
135 | Duodenal stenosis (HP:0100867) | 1.64347798 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.42848712 |
2 | VRK2 | 5.27148451 |
3 | WEE1 | 4.25512837 |
4 | CDC7 | 3.61436275 |
5 | EIF2AK1 | 3.54942661 |
6 | TLK1 | 2.92727272 |
7 | NME2 | 2.90320803 |
8 | NEK1 | 2.63990229 |
9 | STK16 | 2.63650605 |
10 | TSSK6 | 2.45326124 |
11 | SRPK1 | 2.36114279 |
12 | VRK1 | 2.31483257 |
13 | TTK | 2.13731170 |
14 | NEK2 | 2.12397149 |
15 | TESK2 | 2.04221356 |
16 | BCKDK | 2.04066535 |
17 | ACVR1B | 1.99368709 |
18 | SMG1 | 1.98644399 |
19 | PLK4 | 1.92076555 |
20 | EIF2AK3 | 1.91534292 |
21 | PLK1 | 1.80532640 |
22 | RPS6KB2 | 1.70866093 |
23 | BRSK2 | 1.65054325 |
24 | CDK7 | 1.58378613 |
25 | AURKB | 1.56652141 |
26 | TAF1 | 1.55750765 |
27 | PASK | 1.52924852 |
28 | RPS6KA4 | 1.52071847 |
29 | DYRK3 | 1.51783002 |
30 | AURKA | 1.51560575 |
31 | ATR | 1.39028747 |
32 | SCYL2 | 1.37490925 |
33 | EPHA2 | 1.37349029 |
34 | MAP3K8 | 1.34613608 |
35 | PLK3 | 1.30326258 |
36 | KDR | 1.29581435 |
37 | MKNK1 | 1.25888846 |
38 | BRAF | 1.25185171 |
39 | BRSK1 | 1.21043651 |
40 | FLT3 | 1.16591073 |
41 | MAP3K11 | 1.14606830 |
42 | TGFBR1 | 1.12291104 |
43 | CDK4 | 1.05946349 |
44 | NME1 | 1.05662908 |
45 | CCNB1 | 1.05284026 |
46 | PAK4 | 1.05141697 |
47 | PDK2 | 1.04818335 |
48 | IRAK3 | 1.04732341 |
49 | MAPKAPK3 | 1.02817003 |
50 | EEF2K | 1.00051419 |
51 | CHEK2 | 0.98758610 |
52 | PIM2 | 0.98454424 |
53 | ZAK | 0.94761138 |
54 | MST1R | 0.94601188 |
55 | NUAK1 | 0.92898657 |
56 | CHEK1 | 0.89280793 |
57 | STK4 | 0.88771340 |
58 | MAP2K3 | 0.86181805 |
59 | MAP3K10 | 0.81241918 |
60 | STK10 | 0.80847683 |
61 | CSNK1G3 | 0.79753392 |
62 | CSNK2A2 | 0.78016621 |
63 | TESK1 | 0.77424134 |
64 | LRRK2 | 0.76653866 |
65 | MKNK2 | 0.75788917 |
66 | CSNK2A1 | 0.75356727 |
67 | PAK1 | 0.75264524 |
68 | CDK8 | 0.73810437 |
69 | PKN2 | 0.73751246 |
70 | MAP3K12 | 0.68691858 |
71 | CDK2 | 0.64791827 |
72 | ERBB4 | 0.64274452 |
73 | ILK | 0.62977904 |
74 | TRIM28 | 0.62131468 |
75 | CSNK1G1 | 0.61745860 |
76 | PRKCI | 0.58797499 |
77 | ATM | 0.58786666 |
78 | DYRK2 | 0.58310503 |
79 | LIMK1 | 0.58247483 |
80 | EIF2AK2 | 0.57839216 |
81 | ABL2 | 0.57216980 |
82 | PIM1 | 0.56312565 |
83 | STK38L | 0.55760046 |
84 | PBK | 0.55504798 |
85 | PDK3 | 0.54695769 |
86 | PDK4 | 0.54695769 |
87 | CSNK1A1L | 0.54244007 |
88 | CDK9 | 0.53039697 |
89 | LATS2 | 0.52104610 |
90 | AKT2 | 0.49432308 |
91 | RPS6KA5 | 0.48106143 |
92 | MAPKAPK5 | 0.47959726 |
93 | MAP3K3 | 0.46926540 |
94 | MET | 0.43396046 |
95 | ALK | 0.43014534 |
96 | CDK1 | 0.42625762 |
97 | LMTK2 | 0.42246061 |
98 | TAOK2 | 0.41444705 |
99 | ARAF | 0.40803614 |
100 | DAPK3 | 0.40590091 |
101 | MAPK11 | 0.40404129 |
102 | AKT3 | 0.39437524 |
103 | MAP4K2 | 0.39424394 |
104 | CDK11A | 0.38702619 |
105 | DAPK1 | 0.38586538 |
106 | MST4 | 0.34462642 |
107 | CSNK1E | 0.33877299 |
108 | CSNK1G2 | 0.33165313 |
109 | CDK14 | 0.31246706 |
110 | CDK15 | 0.29574539 |
111 | GRK6 | 0.29203911 |
112 | CDK18 | 0.29011858 |
113 | MAP4K1 | 0.28643285 |
114 | BLK | 0.27655823 |
115 | PIK3CG | 0.26156876 |
116 | MAP2K7 | 0.25230325 |
117 | CDK19 | 0.25072451 |
118 | OBSCN | 0.21468256 |
119 | PNCK | 0.21440361 |
120 | PRKDC | 0.20017408 |
121 | CLK1 | 0.19197868 |
122 | MAP3K5 | 0.18888410 |
123 | MELK | 0.18447101 |
124 | FGFR1 | 0.17927395 |
125 | RPS6KC1 | 0.17796014 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.68868438 |
2 | Ribosome_Homo sapiens_hsa03010 | 4.08409607 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.92802195 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.76839888 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.17401236 |
6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.06228378 |
7 | Spliceosome_Homo sapiens_hsa03040 | 2.95409012 |
8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.85328276 |
9 | Base excision repair_Homo sapiens_hsa03410 | 2.74328786 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.62823575 |
11 | RNA transport_Homo sapiens_hsa03013 | 2.61909278 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.59449471 |
13 | Homologous recombination_Homo sapiens_hsa03440 | 2.57398405 |
14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.49612192 |
15 | Cell cycle_Homo sapiens_hsa04110 | 1.99828192 |
16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.60961752 |
17 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.60935457 |
18 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.59105763 |
19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.58313514 |
20 | RNA degradation_Homo sapiens_hsa03018 | 1.53181913 |
21 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.52307957 |
22 | Parkinsons disease_Homo sapiens_hsa05012 | 1.50517814 |
23 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.49684180 |
24 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.48699692 |
25 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.39709269 |
26 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.39607078 |
27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.38293457 |
28 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.29485011 |
29 | Purine metabolism_Homo sapiens_hsa00230 | 1.29149963 |
30 | Carbon metabolism_Homo sapiens_hsa01200 | 1.29065846 |
31 | Huntingtons disease_Homo sapiens_hsa05016 | 1.27754841 |
32 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.24379919 |
33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.22969811 |
34 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.22400268 |
35 | Sulfur relay system_Homo sapiens_hsa04122 | 1.15123355 |
36 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.12470665 |
37 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.10560924 |
38 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.08865208 |
39 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.08569581 |
40 | Protein export_Homo sapiens_hsa03060 | 1.08065904 |
41 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.05894988 |
42 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.05681515 |
43 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.93507605 |
44 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.91380800 |
45 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.90992145 |
46 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.89660208 |
47 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.88666075 |
48 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.85364447 |
49 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.85194697 |
50 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.83417215 |
51 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.80253932 |
52 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.77948699 |
53 | Alzheimers disease_Homo sapiens_hsa05010 | 0.67330972 |
54 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.66300984 |
55 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.64213150 |
56 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.63195591 |
57 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58148001 |
58 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.57716590 |
59 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.57119795 |
60 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.55471761 |
61 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.54635943 |
62 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.53497128 |
63 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.51223606 |
64 | Galactose metabolism_Homo sapiens_hsa00052 | 0.49991911 |
65 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.49555815 |
66 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.49399396 |
67 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.47625313 |
68 | Thyroid cancer_Homo sapiens_hsa05216 | 0.45536683 |
69 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42556113 |
70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.40916788 |
71 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.39319466 |
72 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.37886339 |
73 | Peroxisome_Homo sapiens_hsa04146 | 0.36438330 |
74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35801902 |
75 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.33653038 |
76 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.33207243 |
77 | HTLV-I infection_Homo sapiens_hsa05166 | 0.30740206 |
78 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.30342409 |
79 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.28737408 |
80 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.28138253 |
81 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.27826505 |
82 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.27330321 |
83 | Legionellosis_Homo sapiens_hsa05134 | 0.27327899 |
84 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.27229704 |
85 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.26825255 |
86 | Bladder cancer_Homo sapiens_hsa05219 | 0.23878508 |
87 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.23809429 |
88 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.23557586 |
89 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.22508782 |
90 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.21759375 |
91 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.20480711 |
92 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.19067811 |
93 | Alcoholism_Homo sapiens_hsa05034 | 0.19065595 |
94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.18645091 |
95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.17954376 |
96 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.16886153 |
97 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.15066109 |
98 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.14371278 |
99 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.13567431 |
100 | Retinol metabolism_Homo sapiens_hsa00830 | 0.12393907 |
101 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.12363066 |
102 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.12144011 |
103 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.10929795 |
104 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.10680068 |
105 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.09018120 |
106 | Apoptosis_Homo sapiens_hsa04210 | 0.07333844 |
107 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.07162894 |
108 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.05502314 |
109 | Lysine degradation_Homo sapiens_hsa00310 | 0.05478005 |
110 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.05099259 |