STOML3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1left/right pattern formation (GO:0060972)9.48508117
2protein insertion into membrane (GO:0051205)9.08709843
3primary alcohol catabolic process (GO:0034310)7.23443357
4axoneme assembly (GO:0035082)7.20999340
5protein localization to cilium (GO:0061512)7.20748607
6oligosaccharide catabolic process (GO:0009313)6.72966124
7cilium organization (GO:0044782)6.24386479
8vitamin transmembrane transport (GO:0035461)6.23870748
9cilium movement (GO:0003341)6.03999643
10ethanol metabolic process (GO:0006067)5.93116111
11diterpenoid biosynthetic process (GO:0016102)5.77589559
12regulation of chromatin binding (GO:0035561)5.54290888
13centriole assembly (GO:0098534)5.46315816
14regulation of cilium movement (GO:0003352)5.41922794
15calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)5.34216972
16epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.26126717
17axonemal dynein complex assembly (GO:0070286)5.22998617
18regulation of female gonad development (GO:2000194)5.13060823
19tolerance induction (GO:0002507)5.10661028
20dopamine receptor signaling pathway (GO:0007212)5.00543578
21pyrimidine-containing compound transmembrane transport (GO:0072531)4.95373465
22one-carbon compound transport (GO:0019755)4.86089010
23lung epithelium development (GO:0060428)4.85671768
24microtubule-based movement (GO:0007018)4.84634436
25sperm capacitation (GO:0048240)4.80900229
26cellular component assembly involved in morphogenesis (GO:0010927)4.80044885
27response to xenobiotic stimulus (GO:0009410)4.70178726
28neuron cell-cell adhesion (GO:0007158)4.63747638
29ethanol oxidation (GO:0006069)4.61425021
30negative regulation of T cell differentiation in thymus (GO:0033085)4.53298097
31axonal fasciculation (GO:0007413)4.52953808
32glomerular epithelial cell development (GO:0072310)4.51153969
33establishment of apical/basal cell polarity (GO:0035089)4.50377687
34cellular response to prostaglandin stimulus (GO:0071379)4.49479534
35calcium-mediated signaling using intracellular calcium source (GO:0035584)4.47859133
36behavioral response to cocaine (GO:0048148)4.46992382
37cell projection assembly (GO:0030031)4.38276739
38auditory receptor cell differentiation (GO:0042491)4.34631498
39negative regulation of B cell mediated immunity (GO:0002713)4.31605590
40negative regulation of immunoglobulin mediated immune response (GO:0002890)4.31605590
41protein polyglutamylation (GO:0018095)4.28331348
42cilium morphogenesis (GO:0060271)4.25925308
43glycosphingolipid catabolic process (GO:0046479)4.20973622
44regulation of interleukin-5 production (GO:0032674)4.18325033
45negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)4.14599537
46negative regulation of humoral immune response (GO:0002921)4.10339270
47regulation of germinal center formation (GO:0002634)4.08501589
48terpenoid biosynthetic process (GO:0016114)4.04981779
49positive regulation of tolerance induction (GO:0002645)4.02561008
50retinoic acid metabolic process (GO:0042573)4.01363800
51establishment of monopolar cell polarity (GO:0061162)3.95029216
52establishment or maintenance of monopolar cell polarity (GO:0061339)3.95029216
53inner ear receptor cell differentiation (GO:0060113)3.94569325
54detection of calcium ion (GO:0005513)3.93757931
55sensory perception of taste (GO:0050909)3.92950579
56establishment of planar polarity (GO:0001736)3.92240959
57establishment of tissue polarity (GO:0007164)3.92240959
58epithelial cilium movement (GO:0003351)3.85252933
59cellular response to glucagon stimulus (GO:0071377)3.83540820
60cytoplasmic microtubule organization (GO:0031122)3.77648351
61intraciliary transport (GO:0042073)3.76703105
62glycolipid catabolic process (GO:0019377)3.75813727
63regulation of interleukin-13 production (GO:0032656)3.75250426
64ganglioside metabolic process (GO:0001573)3.74418238
65response to caffeine (GO:0031000)3.72471498
66negative regulation of cytosolic calcium ion concentration (GO:0051481)3.62491954
67microtubule depolymerization (GO:0007019)3.60393056
68lateral ventricle development (GO:0021670)3.53973657
69microtubule bundle formation (GO:0001578)3.52222907
70G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.45940131
71ceramide catabolic process (GO:0046514)3.42711163
72centriole replication (GO:0007099)3.38366908
73natural killer cell mediated immunity (GO:0002228)3.38062210
74natural killer cell mediated cytotoxicity (GO:0042267)3.38062210
75olfactory bulb development (GO:0021772)3.37288622
76exogenous drug catabolic process (GO:0042738)3.36195815
77sodium-independent organic anion transport (GO:0043252)3.35339219
78chemical homeostasis within a tissue (GO:0048875)3.35051426
79cilium or flagellum-dependent cell motility (GO:0001539)3.33380013
80left/right axis specification (GO:0070986)3.32879809
81adipose tissue development (GO:0060612)3.32005746
82retinol metabolic process (GO:0042572)3.31737728
83inositol phosphate catabolic process (GO:0071545)3.31509095
84primary alcohol metabolic process (GO:0034308)3.28335257
85ADP metabolic process (GO:0046031)3.27109936
86microtubule polymerization or depolymerization (GO:0031109)3.26151589
87glutathione derivative biosynthetic process (GO:1901687)3.25388480
88glutathione derivative metabolic process (GO:1901685)3.25388480
89determination of left/right symmetry (GO:0007368)3.25276932
90negative regulation of inclusion body assembly (GO:0090084)3.24430686
91negative regulation of transcription regulatory region DNA binding (GO:2000678)3.20902857
92brain morphogenesis (GO:0048854)3.20704587
93nucleoside diphosphate phosphorylation (GO:0006165)3.20222168
94sphingolipid catabolic process (GO:0030149)3.16701034
95regulation of chemokine secretion (GO:0090196)3.15508381
96regulation of protein kinase A signaling (GO:0010738)3.14378423
97regulation of microtubule-based movement (GO:0060632)3.13570971
98ventricular system development (GO:0021591)3.13051220
99response to amphetamine (GO:0001975)3.12625807
100determination of bilateral symmetry (GO:0009855)3.12571311
101antibacterial humoral response (GO:0019731)3.10998948
102response to monoamine (GO:0071867)3.10158494
103response to catecholamine (GO:0071869)3.10158494
104iron ion import (GO:0097286)3.10004858
105specification of symmetry (GO:0009799)3.06764193
106adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189)3.06482291
107mechanoreceptor differentiation (GO:0042490)3.05353854
108sperm motility (GO:0030317)3.04516743
109innate immune response in mucosa (GO:0002227)3.04232666
110response to prostaglandin E (GO:0034695)3.03982971
111smoothened signaling pathway (GO:0007224)3.01274397
112inositol phosphate dephosphorylation (GO:0046855)3.00107388
113phosphorylated carbohydrate dephosphorylation (GO:0046838)3.00107388
114sensory perception of smell (GO:0007608)20.0786262
115ER overload response (GO:0006983)2.99246492
116regulation of rhodopsin mediated signaling pathway (GO:0022400)2.98941651
117activation of protein kinase A activity (GO:0034199)2.98598759
118tight junction assembly (GO:0070830)2.98391631
119negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.98139688
120regulation of tolerance induction (GO:0002643)2.97486131
121regulation of cell communication by electrical coupling (GO:0010649)2.96526547
122O-glycan processing (GO:0016266)2.96002227
123positive regulation of smoothened signaling pathway (GO:0045880)2.94990874
124neuron recognition (GO:0008038)2.94779426
125positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.92142555
126response to glucagon (GO:0033762)2.89891558
127hydrogen peroxide biosynthetic process (GO:0050665)2.88490746
128regulation of heart rate by cardiac conduction (GO:0086091)2.88209561
129regulation of autophagic vacuole assembly (GO:2000785)2.87805551
130cellular copper ion homeostasis (GO:0006878)2.87061929
131cellular response to monoamine stimulus (GO:0071868)2.85515227
132cellular response to catecholamine stimulus (GO:0071870)2.85515227
133regulation of synapse structural plasticity (GO:0051823)2.84749397
134facial nerve structural organization (GO:0021612)2.83016864
135phototransduction, visible light (GO:0007603)2.81007253
136membrane lipid catabolic process (GO:0046466)2.80603619
137ovulation cycle (GO:0042698)2.80073825
138microtubule-based process (GO:0007017)2.80047164
139antimicrobial humoral response (GO:0019730)2.79953690
140microtubule severing (GO:0051013)2.77876341
141cAMP biosynthetic process (GO:0006171)2.76786635
142response to gravity (GO:0009629)2.75077311
143ganglion development (GO:0061548)2.74379525
144multicellular organismal water homeostasis (GO:0050891)2.72847453
145organelle assembly (GO:0070925)2.68734390
146regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.67312194
147phototransduction (GO:0007602)2.66569688
148hydrogen peroxide catabolic process (GO:0042744)2.66131254
149cellular potassium ion transport (GO:0071804)2.65749650
150potassium ion transmembrane transport (GO:0071805)2.65749650
151aldehyde catabolic process (GO:0046185)2.65578737
152progesterone metabolic process (GO:0042448)2.65335035
153lateral sprouting from an epithelium (GO:0060601)2.64511490
154acrosome reaction (GO:0007340)2.64118775
155rhodopsin mediated signaling pathway (GO:0016056)2.64105314
156regulation of microtubule depolymerization (GO:0031114)2.62130425
157phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.62087688
158synaptic vesicle docking involved in exocytosis (GO:0016081)2.59704782
159cilium assembly (GO:0042384)2.59133540
160drug catabolic process (GO:0042737)2.57653332
161endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.56394105
162reactive oxygen species biosynthetic process (GO:1903409)2.56213263
163neuron projection extension involved in neuron projection guidance (GO:1902284)2.56070202
164axon extension involved in axon guidance (GO:0048846)2.56070202
165atrial cardiac muscle cell action potential (GO:0086014)2.55639308
166carnitine metabolic process (GO:0009437)2.55481705
167apical protein localization (GO:0045176)2.53047746
168GTP biosynthetic process (GO:0006183)2.47317087
169excretion (GO:0007588)2.47027474
170regulation of vacuole organization (GO:0044088)2.44779834
171nucleoside diphosphate metabolic process (GO:0009132)2.43461245
172heart looping (GO:0001947)2.41843598
173phosphatidylcholine biosynthetic process (GO:0006656)2.40754486
174nucleotide phosphorylation (GO:0046939)2.40140355
175oligosaccharide biosynthetic process (GO:0009312)2.35013422
176phenol-containing compound catabolic process (GO:0019336)2.31711829
177water homeostasis (GO:0030104)2.30938292
178regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2.30861383
179hydrogen peroxide metabolic process (GO:0042743)2.30362624
180embryonic camera-type eye development (GO:0031076)2.29534237
181motile cilium assembly (GO:0044458)15.6984156
182sensory perception of chemical stimulus (GO:0007606)12.3752182
183adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)10.2534281

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.53261180
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.02731635
3TAF15_26573619_Chip-Seq_HEK293_Human3.31135216
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.23052651
5ZNF263_19887448_ChIP-Seq_K562_Human3.06748738
6RBPJ_22232070_ChIP-Seq_NCS_Mouse3.04461478
7GBX2_23144817_ChIP-Seq_PC3_Human3.03589591
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.85950190
9DROSHA_22980978_ChIP-Seq_HELA_Human2.85763940
10BMI1_19503595_ChIP-Seq_MEFsC_Mouse2.11537180
11* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.05974903
12PIAS1_25552417_ChIP-Seq_VCAP_Human1.99936410
13TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.96864521
14BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.96638262
15PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.92253531
16EED_16625203_ChIP-ChIP_MESCs_Mouse1.89297867
17EZH2_18974828_ChIP-Seq_MESCs_Mouse1.87210885
18RNF2_18974828_ChIP-Seq_MESCs_Mouse1.87210885
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.84756986
20FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.81794846
21RUNX1_27514584_Chip-Seq_MCF-7_Human1.81045839
22STAT1_20625510_ChIP-Seq_HELA_Human1.80571041
23BMI1_23680149_ChIP-Seq_NPCS_Mouse1.77987095
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.75517251
25VDR_22108803_ChIP-Seq_LS180_Human1.74998711
26SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.73730978
27ZNF217_24962896_ChIP-Seq_MCF-7_Human1.73344024
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.72487168
29SOX2_27498859_Chip-Seq_STOMACH_Mouse1.69984329
30IKZF1_21737484_ChIP-ChIP_HCT116_Human1.69818556
31SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.63900143
32AHR_22903824_ChIP-Seq_MCF-7_Human1.62482696
33GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.60476261
34SMC4_20622854_ChIP-Seq_HELA_Human1.60308245
35SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.59191490
36ESR1_20079471_ChIP-ChIP_T-47D_Human1.57784451
37JARID2_20064375_ChIP-Seq_MESCs_Mouse1.56927881
38ESR2_21235772_ChIP-Seq_MCF-7_Human1.56076192
39SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.55584579
40* TP63_23658742_ChIP-Seq_EP156T_Human1.54259767
41ZFP57_27257070_Chip-Seq_ESCs_Mouse1.54119914
42MTF2_20144788_ChIP-Seq_MESCs_Mouse1.53529517
43POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.52388588
44TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52388588
45SUZ12_27294783_Chip-Seq_ESCs_Mouse1.52214049
46ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.48619654
47CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.47509699
48SOX9_24532713_ChIP-Seq_HFSC_Mouse1.44661404
49AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.44352295
50CDX2_20551321_ChIP-Seq_CACO-2_Human1.44089223
51CTNNB1_20460455_ChIP-Seq_HCT116_Human1.43478737
52CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.43124482
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.42885808
54RAD21_21589869_ChIP-Seq_MESCs_Mouse1.42689997
55SOX2_20726797_ChIP-Seq_SW620_Human1.42385138
56TP63_22573176_ChIP-Seq_HFKS_Human1.39614595
57KLF5_25053715_ChIP-Seq_YYC3_Human1.35925054
58P63_26484246_Chip-Seq_KERATINOCYTES_Human1.35215300
59ARNT_22903824_ChIP-Seq_MCF-7_Human1.33752846
60FOXA1_25552417_ChIP-Seq_VCAP_Human1.33388532
61ELF1_20517297_ChIP-Seq_JURKAT_Human1.32566489
62ETV1_20927104_ChIP-Seq_GIST48_Human1.32195578
63PHF8_20622853_ChIP-Seq_HELA_Human1.31240641
64P300_19829295_ChIP-Seq_ESCs_Human1.30971628
65HNFA_21074721_ChIP-Seq_CACO-2_Human1.30191043
66CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.29106686
67RNF2_27304074_Chip-Seq_NSC_Mouse1.29094118
68REST_21632747_ChIP-Seq_MESCs_Mouse1.26288471
69JARID2_20075857_ChIP-Seq_MESCs_Mouse1.26262117
70* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26208370
71GATA1_19941826_ChIP-Seq_K562_Human1.26084088
72EZH2_27294783_Chip-Seq_ESCs_Mouse1.25354338
73PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.24565786
74CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.23209667
75SMAD4_21799915_ChIP-Seq_A2780_Human1.22923581
76KDM2B_26808549_Chip-Seq_K562_Human1.22922222
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.22853324
78SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.22709345
79* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22313474
80STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.20976432
81SMRT_27268052_Chip-Seq_Bcells_Human1.20755984
82ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.19821980
83ESR1_21235772_ChIP-Seq_MCF-7_Human1.19262591
84SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.18924797
85EZH2_27304074_Chip-Seq_ESCs_Mouse1.18115735
86MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.17733928
87CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.17648835
88* SMAD4_21741376_ChIP-Seq_EPCs_Human1.17557955
89SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.16541771
90TDRD3_21172665_ChIP-Seq_MCF-7_Human1.15772576
91YY1_22570637_ChIP-Seq_MALME-3M_Human1.14093989
92P53_22127205_ChIP-Seq_FIBROBLAST_Human1.13935556
93PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.13615104
94* SMAD3_21741376_ChIP-Seq_EPCs_Human1.13322564
95SRY_22984422_ChIP-ChIP_TESTIS_Rat1.13054428
96NFYA_21822215_ChIP-Seq_K562_Human1.12775082
97TCF4_22108803_ChIP-Seq_LS180_Human1.12381809
98RNF2_27304074_Chip-Seq_ESCs_Mouse1.12365816
99CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11779738
100RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.10950538
101CTCF_20526341_ChIP-Seq_ESCs_Human1.09230279
102GATA1_26923725_Chip-Seq_HPCs_Mouse1.07303262
103GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.06402235
104RBPJ_21746931_ChIP-Seq_IB4_Human1.06352536
105FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05081463
106CTCF_27219007_Chip-Seq_Bcells_Human1.04581527
107ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.04174547
108TP53_18474530_ChIP-ChIP_U2OS_Human1.04045624
109GATA6_21074721_ChIP-Seq_CACO-2_Human1.03891370
110LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03628190
111PPAR_26484153_Chip-Seq_NCI-H1993_Human1.03293390
112GATA4_25053715_ChIP-Seq_YYC3_Human1.02603290
113TP63_17297297_ChIP-ChIP_HaCaT_Human1.02543689
114SMAD3_21741376_ChIP-Seq_HESCs_Human1.02467317
115* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02402961
116KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.02070823
117RARB_27405468_Chip-Seq_BRAIN_Mouse1.02046790
118CBX2_22325352_ChIP-Seq_293T-Rex_Human1.01660443
119BP1_19119308_ChIP-ChIP_Hs578T_Human1.01071814
120TBL1_22424771_ChIP-Seq_293T_Human1.00748303
121GATA3_24758297_ChIP-Seq_MCF-7_Human1.00527716
122TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.99385838
123SMAD4_21741376_ChIP-Seq_HESCs_Human0.99136092
124FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.98389818
125WT1_25993318_ChIP-Seq_PODOCYTE_Human0.98031948
126FOXO3_23340844_ChIP-Seq_DLD1_Human0.98018097
127NFYB_21822215_ChIP-Seq_K562_Human0.97965530
128PRDM14_20953172_ChIP-Seq_ESCs_Human0.97834018
129CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.97548228
130P68_20966046_ChIP-Seq_HELA_Human0.97026511
131RING1B_27294783_Chip-Seq_NPCs_Mouse0.96884643
132* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.96843705
133SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.96023927
134ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.95649819
135STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.95489374
136FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.94737419
137* RUNX2_22187159_ChIP-Seq_PCA_Human0.94292835
138PHF8_20622854_ChIP-Seq_HELA_Human0.94280315
139CREB1_26743006_Chip-Seq_LNCaP_Human0.93992906
140RING1B_27294783_Chip-Seq_ESCs_Mouse0.93729286
141TCF4_18268006_ChIP-ChIP_LS174T_Human0.93517649
142FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.93114918
143STAT3_23295773_ChIP-Seq_U87_Human0.92570095
144FOXA2_19822575_ChIP-Seq_HepG2_Human0.91275552
145CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.91251372
146* CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.91165906
147PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.90073760
148SOX2_21211035_ChIP-Seq_LN229_Human0.89790234
149LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88957068
150SMAD3_21741376_ChIP-Seq_ESCs_Human0.88762443
151* CEBPB_22108803_ChIP-Seq_LS180_Human0.88590442
152P300_27268052_Chip-Seq_Bcells_Human0.87749069
153FLI1_21867929_ChIP-Seq_CD8_Mouse0.87434241
154WDR5_24793694_ChIP-Seq_LNCAP_Human0.86797224
155AR_20517297_ChIP-Seq_VCAP_Human0.85873522
156FOXM1_26456572_ChIP-Seq_MCF-7_Human0.85624995
157GF1_26923725_Chip-Seq_HPCs_Mouse0.85093182
158SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84090441
159EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.83922908
160RACK7_27058665_Chip-Seq_MCF-7_Human0.83922056
161TAL1_26923725_Chip-Seq_HPCs_Mouse0.82578462
162TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.82148121
163EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.81947885
164TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81409858
165SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.81071790
166STAT1_17558387_ChIP-Seq_HELA_Human0.80872417
167POU3F2_20337985_ChIP-ChIP_501MEL_Human0.80735284
168AR_19668381_ChIP-Seq_PC3_Human0.79857793
169SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79339982
170FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.78942989
171* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.78866739
172CDX2_19796622_ChIP-Seq_MESCs_Mouse0.78499666

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot5.75226303
2MP0003878_abnormal_ear_physiology5.75226303
3MP0002132_abnormal_respiratory_system5.19802582
4MP0008789_abnormal_olfactory_epithelium4.79199511
5MP0005499_abnormal_olfactory_system4.32834552
6MP0005394_taste/olfaction_phenotype4.32834552
7MP0004043_abnormal_pH_regulation3.56886630
8MP0009780_abnormal_chondrocyte_physiolo3.27836717
9MP0002277_abnormal_respiratory_mucosa3.27482012
10MP0005645_abnormal_hypothalamus_physiol2.82076961
11MP0003806_abnormal_nucleotide_metabolis2.66063362
12MP0010030_abnormal_orbit_morphology2.55687823
13MP0004019_abnormal_vitamin_homeostasis2.47538220
14MP0002282_abnormal_trachea_morphology2.29498475
15MP0004147_increased_porphyrin_level2.19468020
16MP0001984_abnormal_olfaction13.3223985
17MP0002168_other_aberrant_phenotype1.91741572
18MP0000383_abnormal_hair_follicle1.91541338
19MP0005083_abnormal_biliary_tract1.82547907
20MP0005360_urolithiasis1.76903900
21MP0002184_abnormal_innervation1.72738052
22MP0005646_abnormal_pituitary_gland1.69546785
23MP0001486_abnormal_startle_reflex1.65707265
24MP0010678_abnormal_skin_adnexa1.63371957
25MP0002160_abnormal_reproductive_system1.60149606
26MP0001765_abnormal_ion_homeostasis1.57435202
27MP0002653_abnormal_ependyma_morphology1.53340459
28MP0000678_abnormal_parathyroid_gland1.51433402
29MP0002557_abnormal_social/conspecific_i1.47062731
30MP0002938_white_spotting1.46844315
31MP0000372_irregular_coat_pigmentation1.42032219
32MP0001485_abnormal_pinna_reflex1.39210284
33MP0001542_abnormal_bone_strength1.33388513
34MP0009379_abnormal_foot_pigmentation1.33372604
35MP0005165_increased_susceptibility_to1.30993351
36MP0000465_gastrointestinal_hemorrhage1.30139310
37MP0002249_abnormal_larynx_morphology1.28792854
38MP0004133_heterotaxia1.25816980
39MP0002928_abnormal_bile_duct1.25408879
40MP0004742_abnormal_vestibular_system1.24842750
41MP0002233_abnormal_nose_morphology1.19928354
42MP0005395_other_phenotype1.15288254
43MP0002752_abnormal_somatic_nervous1.14282414
44MP0010155_abnormal_intestine_physiology1.10910418
45MP0005164_abnormal_response_to1.09171333
46MP0000516_abnormal_urinary_system1.06515482
47MP0005367_renal/urinary_system_phenotyp1.06515482
48MP0005636_abnormal_mineral_homeostasis1.00193930
49MP0004883_abnormal_blood_vessel0.99395359
50MP0002822_catalepsy0.99365486
51MP0001963_abnormal_hearing_physiology0.98971765
52MP0000778_abnormal_nervous_system0.94709061
53MP0004858_abnormal_nervous_system0.92709595
54MP0001849_ear_inflammation0.92566345
55MP0001879_abnormal_lymphatic_vessel0.92416371
56MP0002638_abnormal_pupillary_reflex0.91285561
57MP0003635_abnormal_synaptic_transmissio0.91040522
58MP0005389_reproductive_system_phenotype0.90741535
59MP0005408_hypopigmentation0.89968132
60MP0000003_abnormal_adipose_tissue0.88889288
61MP0002882_abnormal_neuron_morphology0.88279879
62MP0005503_abnormal_tendon_morphology0.85124554
63MP0005410_abnormal_fertilization0.85093643
64MP0006276_abnormal_autonomic_nervous0.84830992
65MP0002229_neurodegeneration0.84720842
66MP0009643_abnormal_urine_homeostasis0.83498504
67MP0009765_abnormal_xenobiotic_induced0.80319256
68MP0000026_abnormal_inner_ear0.80179228
69MP0005310_abnormal_salivary_gland0.79691919
70MP0001188_hyperpigmentation0.79139008
71MP0002064_seizures0.78657452
72MP0005085_abnormal_gallbladder_physiolo0.76504473
73* MP0002272_abnormal_nervous_system0.76233835
74MP0002063_abnormal_learning/memory/cond0.75242753
75MP0001929_abnormal_gametogenesis0.73704745
76MP0003698_abnormal_male_reproductive0.73640366
77MP0002136_abnormal_kidney_physiology0.73431211
78MP0003937_abnormal_limbs/digits/tail_de0.71635977
79MP0001324_abnormal_eye_pigmentation0.71323949
80MP0000681_abnormal_thyroid_gland0.71008993
81MP0001270_distended_abdomen0.70072246
82MP0002405_respiratory_system_inflammati0.70049828
83MP0003880_abnormal_central_pattern0.69686385
84MP0002572_abnormal_emotion/affect_behav0.69669422
85MP0002098_abnormal_vibrissa_morphology0.69564753
86MP0002116_abnormal_craniofacial_bone0.69158914
87MP0000467_abnormal_esophagus_morphology0.68935393
88* MP0002734_abnormal_mechanical_nocicepti0.67894673
89MP0005253_abnormal_eye_physiology0.67083412
90MP0005551_abnormal_eye_electrophysiolog0.66991281
91MP0005084_abnormal_gallbladder_morpholo0.64965794
92MP0003656_abnormal_erythrocyte_physiolo0.64686576
93MP0003633_abnormal_nervous_system0.63189980
94MP0003938_abnormal_ear_development0.63004778
95MP0009763_increased_sensitivity_to0.62605210
96MP0001664_abnormal_digestion0.62262060
97MP0009384_cardiac_valve_regurgitation0.62178419
98MP0005248_abnormal_Harderian_gland0.62021172
99MP0002152_abnormal_brain_morphology0.61781272
100MP0003303_peritoneal_inflammation0.61275218
101MP0002067_abnormal_sensory_capabilities0.60865866
102MP0008875_abnormal_xenobiotic_pharmacok0.60359720
103MP0003252_abnormal_bile_duct0.59536298
104MP0004782_abnormal_surfactant_physiolog0.58342887
105MP0000566_synostosis0.57001511
106MP0005623_abnormal_meninges_morphology0.55937558
107MP0004811_abnormal_neuron_physiology0.55409657
108MP0006082_CNS_inflammation0.55091100
109MP0009703_decreased_birth_body0.54897476
110MP0002084_abnormal_developmental_patter0.54870661
111MP0004264_abnormal_extraembryonic_tissu0.53276951
112MP0003631_nervous_system_phenotype0.53010772
113MP0005508_abnormal_skeleton_morphology0.51738548
114MP0009745_abnormal_behavioral_response0.51201226
115MP0000762_abnormal_tongue_morphology0.51158649
116MP0000858_altered_metastatic_potential0.49563434
117MP0009046_muscle_twitch0.48976325
118MP0002009_preneoplasia0.48835065
119MP0001299_abnormal_eye_distance/0.48317193
120MP0001501_abnormal_sleep_pattern0.47312808
121MP0003634_abnormal_glial_cell0.47208218
122MP0002877_abnormal_melanocyte_morpholog0.47171493
123MP0003943_abnormal_hepatobiliary_system0.46826741
124MP0000049_abnormal_middle_ear0.46522550
125MP0003075_altered_response_to0.45900235
126MP0005391_vision/eye_phenotype0.45897691
127MP0001944_abnormal_pancreas_morphology0.45726246
128MP0008874_decreased_physiological_sensi0.44988093
129MP0004859_abnormal_synaptic_plasticity0.44857323
130MP0001666_abnormal_nutrient_absorption0.44575294
131MP0002735_abnormal_chemical_nociception0.42900156
132MP0004145_abnormal_muscle_electrophysio0.42881581
133MP0003195_calcinosis0.42800007
134MP0004885_abnormal_endolymph0.42736346
135MP0005174_abnormal_tail_pigmentation0.41802262
136MP0004924_abnormal_behavior0.41181651
137MP0005386_behavior/neurological_phenoty0.41181651
138MP0003718_maternal_effect0.40713561
139MP0001346_abnormal_lacrimal_gland0.38681481
140MP0002876_abnormal_thyroid_physiology0.37212637
141MP0000015_abnormal_ear_pigmentation0.36700087
142MP0010234_abnormal_vibrissa_follicle0.36512931
143MP0005171_absent_coat_pigmentation0.34870840
144MP0005220_abnormal_exocrine_pancreas0.34621807
145MP0002896_abnormal_bone_mineralization0.32465477
146MP0003861_abnormal_nervous_system0.32257490
147MP0004270_analgesia0.31498824
148MP0001293_anophthalmia0.30529786
149MP0005365_abnormal_bile_salt0.30400685
150MP0003136_yellow_coat_color0.30152025
151MP0002139_abnormal_hepatobiliary_system0.30074951
152MP0002066_abnormal_motor_capabilities/c0.30065043
153MP0005195_abnormal_posterior_eye0.29580621
154MP0003942_abnormal_urinary_system0.29410556
155MP0000631_abnormal_neuroendocrine_gland0.28826577
156MP0001177_atelectasis0.28679855
157MP0002909_abnormal_adrenal_gland0.28500013
158MP0001529_abnormal_vocalization0.28347158
159MP0005584_abnormal_enzyme/coenzyme_acti0.28134354
160MP0001919_abnormal_reproductive_system0.27886959

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)7.92247431
2Abnormal ciliary motility (HP:0012262)7.86567887
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)7.70310337
4Nasal polyposis (HP:0100582)6.91356247
5Abnormality of macular pigmentation (HP:0008002)6.77055993
6Abnormal respiratory epithelium morphology (HP:0012253)6.52893069
7Abnormal respiratory motile cilium morphology (HP:0005938)6.52893069
8Rhinitis (HP:0012384)6.34390777
9Limb dystonia (HP:0002451)5.78071230
10Abnormality of the nasal mucosa (HP:0000433)5.74154670
11Abnormality of midbrain morphology (HP:0002418)5.14307383
12Molar tooth sign on MRI (HP:0002419)5.14307383
13Retinal dysplasia (HP:0007973)4.88889753
14Palpitations (HP:0001962)4.64012579
15Atonic seizures (HP:0010819)4.49731685
16Bronchitis (HP:0012387)4.36982040
17Bifid tongue (HP:0010297)4.28661497
18Infertility (HP:0000789)4.28044157
19Dysphonia (HP:0001618)4.04999371
20Hypothermia (HP:0002045)3.93008862
21Chronic bronchitis (HP:0004469)3.91090159
22Bronchiectasis (HP:0002110)3.65607871
23Male infertility (HP:0003251)3.61055875
24Pancreatic fibrosis (HP:0100732)3.44677238
25True hermaphroditism (HP:0010459)3.35616731
26Chronic hepatic failure (HP:0100626)3.23502343
27Febrile seizures (HP:0002373)3.22721335
28Absent/shortened dynein arms (HP:0200106)3.17049291
29Dynein arm defect of respiratory motile cilia (HP:0012255)3.17049291
30Torticollis (HP:0000473)3.13484265
31Chronic otitis media (HP:0000389)3.04707412
32Gait imbalance (HP:0002141)3.01718238
33Occipital encephalocele (HP:0002085)2.99850762
34Insomnia (HP:0100785)2.96929455
35Renovascular hypertension (HP:0100817)2.93678135
36Congenital primary aphakia (HP:0007707)2.92947563
37Abnormality of the diencephalon (HP:0010662)2.91901494
38Hyperacusis (HP:0010780)2.80987058
39Syncope (HP:0001279)2.80852164
40Potter facies (HP:0002009)2.79730246
41Facial shape deformation (HP:0011334)2.79730246
42Postaxial hand polydactyly (HP:0001162)2.78011478
43Hyperactive renin-angiotensin system (HP:0000841)2.77943801
44Elfin facies (HP:0004428)2.71841400
45Pancreatic cysts (HP:0001737)2.71428185
46Xerostomia (HP:0000217)2.65790911
47White forelock (HP:0002211)2.64729513
48Medial flaring of the eyebrow (HP:0010747)2.64713604
49Poor coordination (HP:0002370)2.64133130
50Nephrogenic diabetes insipidus (HP:0009806)2.64033862
51Overriding aorta (HP:0002623)2.61129406
52Craniofacial dystonia (HP:0012179)2.60266284
53Asymmetry of the thorax (HP:0001555)2.58417554
54Absence seizures (HP:0002121)2.56290615
55Recurrent sinusitis (HP:0011108)2.47265020
56Anosmia (HP:0000458)2.44494253
57Bony spicule pigmentary retinopathy (HP:0007737)2.42161252
58Focal dystonia (HP:0004373)2.39880559
59Postaxial foot polydactyly (HP:0001830)2.39782705
60Tubulointerstitial nephritis (HP:0001970)2.39416963
61Cystic liver disease (HP:0006706)2.37092270
62Abolished electroretinogram (ERG) (HP:0000550)2.34113928
63Patchy hypopigmentation of hair (HP:0011365)2.24605010
64Flat cornea (HP:0007720)2.23740682
65Vaginal atresia (HP:0000148)2.18020040
66Renal duplication (HP:0000075)2.17548361
67Severe visual impairment (HP:0001141)2.16055722
68Anencephaly (HP:0002323)2.15247139
69Genital tract atresia (HP:0001827)2.14996371
70Systemic lupus erythematosus (HP:0002725)2.11987358
71Oculomotor apraxia (HP:0000657)2.10568935
72Chronic sinusitis (HP:0011109)2.10427858
73Agitation (HP:0000713)2.09874562
74Hyperglycinemia (HP:0002154)2.03777828
75Prolonged QT interval (HP:0001657)1.99271195
76Abnormality of the renal medulla (HP:0100957)1.96984967
77Atelectasis (HP:0100750)1.94395526
78Nephronophthisis (HP:0000090)1.92338895
79Bell-shaped thorax (HP:0001591)1.91643996
80Recurrent bronchitis (HP:0002837)1.90616024
81Congenital hepatic fibrosis (HP:0002612)1.89959903
82Abnormal biliary tract physiology (HP:0012439)1.89502268
83Bile duct proliferation (HP:0001408)1.89502268
84Absent frontal sinuses (HP:0002688)1.86488004
85Focal seizures (HP:0007359)1.85718646
86Furrowed tongue (HP:0000221)1.83766408
87Dialeptic seizures (HP:0011146)1.82313362
88Complete atrioventricular canal defect (HP:0001674)1.77323014
89Thoracolumbar scoliosis (HP:0002944)1.77092417
90Aganglionic megacolon (HP:0002251)1.76790332
91Male pseudohermaphroditism (HP:0000037)1.76431004
92Tubular atrophy (HP:0000092)1.76242270
93Aplasia/Hypoplasia of the lens (HP:0008063)1.76164075
94Aplasia involving bones of the upper limbs (HP:0009823)1.74419818
95Aplasia of the phalanges of the hand (HP:0009802)1.74419818
96Aplasia involving bones of the extremities (HP:0009825)1.74419818
97Progressive macrocephaly (HP:0004481)1.72651599
98Acute necrotizing encephalopathy (HP:0006965)1.72458372
99Abnormality of sodium homeostasis (HP:0010931)1.72258875
100Sclerocornea (HP:0000647)1.72184713
101Recurrent otitis media (HP:0000403)1.70603822
102Generalized tonic-clonic seizures (HP:0002069)1.70301448
103Median cleft lip (HP:0000161)1.70034206
104Renal hypoplasia (HP:0000089)1.68343423
105Abnormality of permanent molar morphology (HP:0011071)1.67836507
106Abnormality of the dental root (HP:0006486)1.67836507
107Taurodontia (HP:0000679)1.67836507
108Aplasia/Hypoplasia of the tongue (HP:0010295)1.67831767
109Atrioventricular canal defect (HP:0006695)1.66483007
110Renal salt wasting (HP:0000127)1.66398556
111Decreased circulating renin level (HP:0003351)1.65958754
112Asplenia (HP:0001746)1.65884685
113Aplasia/Hypoplasia of the spleen (HP:0010451)1.64065538
114Retinitis pigmentosa (HP:0000510)1.62061042
115Short nail (HP:0001799)1.61153381
116Impaired pain sensation (HP:0007328)1.60966684
117Abnormality of pain sensation (HP:0010832)1.60966684
118Asthma (HP:0002099)1.60806921
119Nephropathy (HP:0000112)1.59417028
120Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.46470878
121Tubulointerstitial abnormality (HP:0001969)1.43512559
122Preaxial hand polydactyly (HP:0001177)1.38032507
123Hyperkalemia (HP:0002153)1.37408859
124Hyperaldosteronism (HP:0000859)1.32247514
125Absent rod-and cone-mediated responses on ERG (HP:0007688)1.31758308
126Stage 5 chronic kidney disease (HP:0003774)1.26036949
127Abnormality of dentin (HP:0010299)1.23260156
128Abnormality of renin-angiotensin system (HP:0000847)1.21578728
129Short thorax (HP:0010306)1.19160890
130Abnormality of chloride homeostasis (HP:0011422)1.16673308
131Abnormality of the frontal sinuses (HP:0002687)1.16637432
132Abnormality of the distal phalanges of the toes (HP:0010182)1.16601910
133Abnormality of molar (HP:0011077)1.15897664
134Abnormality of molar morphology (HP:0011070)1.15897664
135Cone-rod dystrophy (HP:0000548)1.15536564
136Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.14802838
137Abnormality of the dental pulp (HP:0006479)1.12809710
138Decreased central vision (HP:0007663)1.12009976
139Hypokalemic alkalosis (HP:0001949)1.11763985
140Bifid scrotum (HP:0000048)1.10670494
141Tubulointerstitial fibrosis (HP:0005576)1.09290634
142Glucose intolerance (HP:0000833)1.06671299
143Hand muscle atrophy (HP:0009130)1.05847548
144Hyponatremia (HP:0002902)1.01554903
145Supernumerary spleens (HP:0009799)1.01416243
146Broad distal phalanx of finger (HP:0009836)0.98316200
147Abnormal drinking behavior (HP:0030082)0.97862987
148Polydipsia (HP:0001959)0.97862987
149Abdominal situs inversus (HP:0003363)0.97469879
150Abnormality of abdominal situs (HP:0011620)0.97469879
151Aplasia of the musculature (HP:0100854)0.97304943
152Short femoral neck (HP:0100864)0.97259968
153Abnormal rod and cone electroretinograms (HP:0008323)0.95540779
154Fetal akinesia sequence (HP:0001989)0.92745604

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B5.94505092
2STK38L4.52148403
3EPHA24.29392137
4STK244.20009949
5MAPK154.09332809
6DAPK23.47476828
7ERBB33.33318142
8RIPK13.29031401
9PHKG12.94564851
10PHKG22.94564851
11CAMK2D2.13222424
12CAMK2B2.07679024
13MAP3K22.07299519
14PAK32.05170022
15NME11.81066571
16STK161.75441387
17SMG11.74269701
18FRK1.69340945
19MAP3K121.60847844
20MAP3K31.59725186
21CAMK2G1.57792348
22MARK11.56651813
23CSK1.55863345
24TTK1.53990834
25NUAK11.53290979
26TNIK1.41869269
27CSNK1A1L1.41553154
28CAMK1G1.34978214
29PNCK1.34328260
30SIK21.31606772
31BMPR21.29208657
32AKT31.24305336
33DAPK11.23388927
34CSNK1G31.20477448
35BCR1.20275208
36CASK1.19574607
37TAOK21.15482135
38ARAF1.10871212
39LRRK21.08072795
40CSNK1G21.07758136
41MAPK131.04307918
42CSNK1G10.99864204
43NEK60.99858147
44TRIB30.99799455
45CAMKK20.96890508
46PRKCG0.93904364
47WNK10.90470222
48STK100.89219141
49GRK60.89001260
50TLK10.87436227
51RIPK40.87125225
52ILK0.86847413
53MST1R0.85275262
54MAP3K140.84496105
55PIM20.84214068
56EPHB10.83233781
57CAMK2A0.81373757
58CAMK1D0.73702380
59RPS6KB20.73661490
60ICK0.72855747
61RPS6KA20.72821937
62MINK10.72114600
63HIPK20.69744716
64MARK20.68519023
65SGK2230.67936469
66SGK4940.67936469
67TESK10.67647835
68IKBKE0.67361995
69GRK50.66089123
70ERBB20.65099544
71BRSK20.63439778
72SGK20.63387466
73MAP2K70.62064755
74PRKCI0.60994692
75MAP3K70.60493830
76SRPK10.60401491
77NTRK20.59693490
78PASK0.59074275
79OXSR10.58742902
80CCNB10.57609677
81AURKA0.56626287
82NLK0.55278796
83STK380.55250034
84EPHA30.54785078
85MAP2K40.54401221
86MUSK0.54173161
87DAPK30.53577558
88DYRK1B0.53500401
89PLK20.53174258
90CAMK40.52014254
91CAMK10.50378356
92MAPKAPK20.50309139
93CAMKK10.48758248
94PRKCD0.48328011
95STK390.47153630
96FGFR20.46249269
97PINK10.45602664
98MAP2K20.45328201
99ROCK20.43874807
100MAP3K40.43458147
101PAK40.42465986
102EEF2K0.40728356
103TSSK60.40311572
104PRKCQ0.38292758
105BRAF0.36669602
106CDK30.36417800
107SGK10.35486016
108SGK30.35408467
109DYRK1A0.34024909
110STK110.33693669
111LMTK20.32790310
112MAPKAPK50.31768358
113PRKCE0.31134673
114CHUK0.31072028
115MAPK70.30780578
116MAPKAPK30.30725391
117CDK50.30312565
118TXK0.29715826
119ADRBK10.29075981
120MYLK0.28953946
121MAP3K110.28933611
122PRKCZ0.28100655
123AKT20.27940006
124RET0.26712776
125NEK90.26406491
126PKN10.25174252
127PRKCA0.25120673
128ZAK0.24756324
129EPHA40.24316292
130TRPM70.24098951
131ROCK10.23975909
132PTK2B0.23231772
133MET0.22607035
134CDK190.22352036
135PLK30.22275295
136IRAK10.21859884
137TBK10.21774905
138PDPK10.21707636
139INSRR0.21391603
140PRKACA0.21313254
141PRKAA20.21259090
142RPS6KA60.21238218
143ABL10.21229270
144MST40.20643248
145FGFR30.19829051
146FYN0.19100160
147CDC42BPA0.17376095
148LATS10.17183434
149WEE10.16946351
150PLK10.16844411
151FER0.16575963
152TAOK10.16387247
153SRC0.15158893
154EGFR0.14351907
155DMPK0.13478859
156WNK30.12747745
157GRK10.12601695

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003605.00374510
2Tyrosine metabolism_Homo sapiens_hsa003503.96568965
3Phototransduction_Homo sapiens_hsa047443.43693442
4Glutathione metabolism_Homo sapiens_hsa004802.92546432
5Other glycan degradation_Homo sapiens_hsa005112.28600100
6Caffeine metabolism_Homo sapiens_hsa002322.24250451
7Olfactory transduction_Homo sapiens_hsa0474011.4687632
8Morphine addiction_Homo sapiens_hsa050321.94980028
9Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.93900451
10Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.85394587
11Taste transduction_Homo sapiens_hsa047421.84741205
12Linoleic acid metabolism_Homo sapiens_hsa005911.81279854
13Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.78886613
14Circadian entrainment_Homo sapiens_hsa047131.75899074
15Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.72386955
16GABAergic synapse_Homo sapiens_hsa047271.58400985
17Pentose and glucuronate interconversions_Homo sapiens_hsa000401.57488214
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.51800094
19Dopaminergic synapse_Homo sapiens_hsa047281.51770779
20Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.50942396
21Glutamatergic synapse_Homo sapiens_hsa047241.45379644
22Synaptic vesicle cycle_Homo sapiens_hsa047211.43111110
23Cholinergic synapse_Homo sapiens_hsa047251.40261494
24Vibrio cholerae infection_Homo sapiens_hsa051101.26332876
25Collecting duct acid secretion_Homo sapiens_hsa049661.22794352
26Insulin secretion_Homo sapiens_hsa049111.21885855
27Gastric acid secretion_Homo sapiens_hsa049711.20130809
28Fatty acid degradation_Homo sapiens_hsa000711.19341021
29Drug metabolism - other enzymes_Homo sapiens_hsa009831.17340414
30Sulfur relay system_Homo sapiens_hsa041221.17010771
31Sulfur metabolism_Homo sapiens_hsa009201.16663939
32cAMP signaling pathway_Homo sapiens_hsa040241.15797129
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.11758074
34Ovarian steroidogenesis_Homo sapiens_hsa049131.10148949
35Bile secretion_Homo sapiens_hsa049761.04502139
36Sphingolipid metabolism_Homo sapiens_hsa006001.02394355
37Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.01694363
38Arachidonic acid metabolism_Homo sapiens_hsa005901.01266839
39Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.99576316
40Salivary secretion_Homo sapiens_hsa049700.98078784
41Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.96765379
42Serotonergic synapse_Homo sapiens_hsa047260.93036518
43Parkinsons disease_Homo sapiens_hsa050120.89631903
44Hedgehog signaling pathway_Homo sapiens_hsa043400.89038171
45Alcoholism_Homo sapiens_hsa050340.87363144
46Notch signaling pathway_Homo sapiens_hsa043300.86515703
47Starch and sucrose metabolism_Homo sapiens_hsa005000.86182416
48cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83365511
49Carbohydrate digestion and absorption_Homo sapiens_hsa049730.83213659
50Chemical carcinogenesis_Homo sapiens_hsa052040.83053259
51Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.82387907
52Calcium signaling pathway_Homo sapiens_hsa040200.76724060
53Basal cell carcinoma_Homo sapiens_hsa052170.76324278
54Steroid hormone biosynthesis_Homo sapiens_hsa001400.75348138
55beta-Alanine metabolism_Homo sapiens_hsa004100.74911810
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73364830
57Circadian rhythm_Homo sapiens_hsa047100.71495599
58Oxidative phosphorylation_Homo sapiens_hsa001900.71447064
59Histidine metabolism_Homo sapiens_hsa003400.70882299
60Amphetamine addiction_Homo sapiens_hsa050310.70294260
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.68336412
62Thyroid hormone synthesis_Homo sapiens_hsa049180.67510244
63Retinol metabolism_Homo sapiens_hsa008300.63873137
64GnRH signaling pathway_Homo sapiens_hsa049120.58811228
65Melanogenesis_Homo sapiens_hsa049160.58684263
66Alzheimers disease_Homo sapiens_hsa050100.58087269
67Renin secretion_Homo sapiens_hsa049240.57605617
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55811233
69Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.55423616
70ABC transporters_Homo sapiens_hsa020100.55309889
71Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55162209
72Adherens junction_Homo sapiens_hsa045200.52702845
73Glycerophospholipid metabolism_Homo sapiens_hsa005640.52201010
74Hepatitis C_Homo sapiens_hsa051600.51950555
75Choline metabolism in cancer_Homo sapiens_hsa052310.51594239
76Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50337265
77Estrogen signaling pathway_Homo sapiens_hsa049150.50299335
78Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.49577350
79Primary bile acid biosynthesis_Homo sapiens_hsa001200.48832116
80Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.48284619
81Fatty acid biosynthesis_Homo sapiens_hsa000610.48014794
82Mineral absorption_Homo sapiens_hsa049780.48007614
83Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47950711
84Long-term potentiation_Homo sapiens_hsa047200.46689202
85Ras signaling pathway_Homo sapiens_hsa040140.46617544
86Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.46246005
87Tight junction_Homo sapiens_hsa045300.46011100
88Complement and coagulation cascades_Homo sapiens_hsa046100.45797413
89Melanoma_Homo sapiens_hsa052180.45512526
90Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.44333352
91Huntingtons disease_Homo sapiens_hsa050160.43996110
92PPAR signaling pathway_Homo sapiens_hsa033200.42757543
93Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41832443
94Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.41650007
95Nicotine addiction_Homo sapiens_hsa050330.39890022
96Amoebiasis_Homo sapiens_hsa051460.39626722
97Glucagon signaling pathway_Homo sapiens_hsa049220.39164910
98Oxytocin signaling pathway_Homo sapiens_hsa049210.38584442
99Hematopoietic cell lineage_Homo sapiens_hsa046400.38146364
100Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37816262
101Pancreatic secretion_Homo sapiens_hsa049720.37220459
102Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.36877918
103Rap1 signaling pathway_Homo sapiens_hsa040150.35643739
104Metabolic pathways_Homo sapiens_hsa011000.34324917
105Peroxisome_Homo sapiens_hsa041460.32743437
106Hippo signaling pathway_Homo sapiens_hsa043900.32252573
107Purine metabolism_Homo sapiens_hsa002300.30648469
108Vascular smooth muscle contraction_Homo sapiens_hsa042700.30329862
109Axon guidance_Homo sapiens_hsa043600.30079771
110Cardiac muscle contraction_Homo sapiens_hsa042600.28955601
111Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.28414434
112Cocaine addiction_Homo sapiens_hsa050300.27496148
113Gap junction_Homo sapiens_hsa045400.25255840
114Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.24183353
115Prion diseases_Homo sapiens_hsa050200.23079794
116Vitamin digestion and absorption_Homo sapiens_hsa049770.22918670
117Pyruvate metabolism_Homo sapiens_hsa006200.22747711
118Insulin signaling pathway_Homo sapiens_hsa049100.21691562
119Arginine and proline metabolism_Homo sapiens_hsa003300.20973311
120Chemokine signaling pathway_Homo sapiens_hsa040620.20106006
121Systemic lupus erythematosus_Homo sapiens_hsa053220.20051744
122SNARE interactions in vesicular transport_Homo sapiens_hsa041300.19531474
123Glioma_Homo sapiens_hsa052140.19481025
124Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.19409487
125Nitrogen metabolism_Homo sapiens_hsa009100.18391562
126Dilated cardiomyopathy_Homo sapiens_hsa054140.18028603
127Leukocyte transendothelial migration_Homo sapiens_hsa046700.17879532
128Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.17754769
129Lysosome_Homo sapiens_hsa041420.17637412
130Wnt signaling pathway_Homo sapiens_hsa043100.17560413
131Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.17484247
132Glycosaminoglycan degradation_Homo sapiens_hsa005310.17018369
133Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.16125836
134Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.15420895
135alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.14921222
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.13972673
137Insulin resistance_Homo sapiens_hsa049310.13642967
138Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.13436065
139FoxO signaling pathway_Homo sapiens_hsa040680.13257946
140Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.13085974
141Tryptophan metabolism_Homo sapiens_hsa003800.12066843
142Cyanoamino acid metabolism_Homo sapiens_hsa004600.11740067
143Type I diabetes mellitus_Homo sapiens_hsa049400.11258389
144Sphingolipid signaling pathway_Homo sapiens_hsa040710.08666575
145ECM-receptor interaction_Homo sapiens_hsa045120.07681521

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