STPG2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cytosolic calcium ion concentration (GO:0051481)9.98280081
2motile cilium assembly (GO:0044458)9.86435561
3reproduction (GO:0000003)9.85800731
4acrosome reaction (GO:0007340)9.77084089
5piRNA metabolic process (GO:0034587)9.70319424
6binding of sperm to zona pellucida (GO:0007339)9.61268362
7male meiosis (GO:0007140)9.15849337
8negative regulation of cAMP-mediated signaling (GO:0043951)8.87460255
9epithelial cilium movement (GO:0003351)8.59811675
10spermatid development (GO:0007286)8.35239732
11behavioral response to ethanol (GO:0048149)7.78597721
12single fertilization (GO:0007338)7.67454335
13cilium movement (GO:0003341)7.67382662
14epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.64627019
15synaptonemal complex organization (GO:0070193)7.64456473
16negative regulation of calcium ion-dependent exocytosis (GO:0045955)7.50572591
17synaptonemal complex assembly (GO:0007130)7.48110085
18regulation of cilium movement (GO:0003352)7.30527649
19opioid receptor signaling pathway (GO:0038003)6.61723873
20adult feeding behavior (GO:0008343)6.57123243
21fertilization (GO:0009566)6.30621861
22DNA methylation involved in gamete generation (GO:0043046)6.30476965
23sperm capacitation (GO:0048240)6.17783678
24ether lipid metabolic process (GO:0046485)5.72009297
25spermatogenesis (GO:0007283)5.49349431
26male gamete generation (GO:0048232)5.47418599
27adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)5.46759945
28chromosome organization involved in meiosis (GO:0070192)5.39717729
29negative regulation of inclusion body assembly (GO:0090084)5.33679447
30male meiosis I (GO:0007141)5.31711243
31regulation of translational termination (GO:0006449)5.15969063
32microtubule depolymerization (GO:0007019)5.14661610
33regulation of protein glycosylation (GO:0060049)5.10897698
34meiotic nuclear division (GO:0007126)5.10441558
35gamete generation (GO:0007276)5.05374198
36cellular process involved in reproduction in multicellular organism (GO:0022412)5.03332128
37cell recognition (GO:0008037)5.00599801
38ventricular system development (GO:0021591)4.88813740
39organic cation transport (GO:0015695)4.88612922
40positive regulation of cAMP-mediated signaling (GO:0043950)4.86501737
41calcium ion-dependent exocytosis (GO:0017156)4.83150149
42germ cell development (GO:0007281)4.79899773
43spermatid nucleus differentiation (GO:0007289)4.59424249
44seminiferous tubule development (GO:0072520)4.46515272
45meiosis I (GO:0007127)4.43180013
46protein localization to cilium (GO:0061512)4.38169164
47regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.33934815
48meiotic cell cycle (GO:0051321)4.30919142
49regulation of inclusion body assembly (GO:0090083)4.20257787
50sphingosine metabolic process (GO:0006670)4.14596104
51regulation of microtubule-based movement (GO:0060632)4.08385011
52centriole assembly (GO:0098534)4.05781334
53microtubule severing (GO:0051013)4.04958067
54coenzyme catabolic process (GO:0009109)4.04540807
55sphingoid metabolic process (GO:0046519)4.03682484
56thrombin receptor signaling pathway (GO:0070493)3.95817643
57multicellular organismal reproductive process (GO:0048609)3.94159445
58regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.92001503
59monoubiquitinated protein deubiquitination (GO:0035520)3.86057250
60cornea development in camera-type eye (GO:0061303)3.77482284
61diol metabolic process (GO:0034311)3.71996257
62DNA replication-dependent nucleosome organization (GO:0034723)3.68301012
63DNA replication-dependent nucleosome assembly (GO:0006335)3.68301012
64regulation of cAMP-mediated signaling (GO:0043949)3.68093703
65negative regulation of nitric oxide biosynthetic process (GO:0045019)3.66879676
66centriole replication (GO:0007099)3.63086698
67detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.59242083
68regulation of glutamate receptor signaling pathway (GO:1900449)3.59032699
69intraciliary transport (GO:0042073)3.56220285
70ncRNA catabolic process (GO:0034661)3.55906821
71gene silencing by RNA (GO:0031047)3.53559535
72regulation of calcium ion-dependent exocytosis (GO:0017158)3.53397611
73cellular response to ammonium ion (GO:0071242)3.48571356
74chaperone-mediated protein complex assembly (GO:0051131)3.43654798
75synapsis (GO:0007129)3.43375030
76left/right pattern formation (GO:0060972)3.42556714
77regulation of female receptivity (GO:0045924)3.39281770
78protein polyglutamylation (GO:0018095)3.36396283
79retinal cone cell development (GO:0046549)3.31371201
80indolalkylamine metabolic process (GO:0006586)3.28462237
81response to pheromone (GO:0019236)3.27511824
82multicellular organismal development (GO:0007275)3.26561115
83detection of light stimulus involved in visual perception (GO:0050908)3.25022902
84detection of light stimulus involved in sensory perception (GO:0050962)3.25022902
85protein K11-linked deubiquitination (GO:0035871)3.20657771
86glycerol ether metabolic process (GO:0006662)3.17982165
87genitalia morphogenesis (GO:0035112)3.17861814
88axoneme assembly (GO:0035082)3.14240652
89RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.10691725
90pyrimidine dimer repair (GO:0006290)3.10461329
91regulation of meiosis I (GO:0060631)3.09857211
92meiotic cell cycle process (GO:1903046)3.08797624
93positive regulation of fatty acid transport (GO:2000193)3.08304232
94signal peptide processing (GO:0006465)3.07758650
95glycerophospholipid catabolic process (GO:0046475)3.07536057
96cilium organization (GO:0044782)3.07502316
97photoreceptor cell maintenance (GO:0045494)3.06341070
98behavioral response to nicotine (GO:0035095)3.05723002
99negative regulation of glycoprotein biosynthetic process (GO:0010561)3.04729763
100alditol metabolic process (GO:0019400)3.03729392
101microtubule-based movement (GO:0007018)3.02221500
102tachykinin receptor signaling pathway (GO:0007217)3.01800743
103cellular ketone body metabolic process (GO:0046950)3.00457795
104membrane depolarization during action potential (GO:0086010)3.00406523
105cellular response to alkaloid (GO:0071312)3.00388502
106regulation of spindle checkpoint (GO:0090231)3.00199825
107neuronal action potential (GO:0019228)2.99802149
108cilium assembly (GO:0042384)2.98884976
109cilium morphogenesis (GO:0060271)2.98462554
110regulation of centriole replication (GO:0046599)2.98158785
111lactate metabolic process (GO:0006089)2.96213089
112cellular component assembly involved in morphogenesis (GO:0010927)2.93685102
113polyol catabolic process (GO:0046174)2.92955698
114ether metabolic process (GO:0018904)2.92207579
115proline transport (GO:0015824)2.92023395
116glycerol metabolic process (GO:0006071)2.85236003
117mRNA cleavage (GO:0006379)2.84907432
118negative regulation of exocytosis (GO:0045920)2.83624483
119chromosome condensation (GO:0030261)2.78281794
120female mating behavior (GO:0060180)2.76882372
121positive regulation of icosanoid secretion (GO:0032305)2.76851424
122microtubule polymerization or depolymerization (GO:0031109)2.76422065
123carnitine transport (GO:0015879)2.76099052
124amino-acid betaine transport (GO:0015838)2.76099052
125detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.75486355
126thyroid hormone metabolic process (GO:0042403)2.73803128
127detection of chemical stimulus involved in sensory perception (GO:0050907)2.71009749
128resolution of meiotic recombination intermediates (GO:0000712)2.69136457
129carnitine transmembrane transport (GO:1902603)2.68684337
130tryptophan catabolic process (GO:0006569)2.67119404
131indole-containing compound catabolic process (GO:0042436)2.67119404
132indolalkylamine catabolic process (GO:0046218)2.67119404
133DNA packaging (GO:0006323)2.66581279
134notochord development (GO:0030903)2.66041796
135left/right axis specification (GO:0070986)2.65662968
136phosphatidylethanolamine metabolic process (GO:0046337)2.63922853
137preassembly of GPI anchor in ER membrane (GO:0016254)2.63020227
138cAMP catabolic process (GO:0006198)2.62608641
139ketone body metabolic process (GO:1902224)2.62297782
140negative regulation of adenylate cyclase activity (GO:0007194)2.62066326
141adaptation of signaling pathway (GO:0023058)2.61765800
142single-organism membrane fusion (GO:0044801)2.61405988
143sister chromatid cohesion (GO:0007062)2.60906272
144negative regulation of organelle assembly (GO:1902116)2.59715772
145response to caffeine (GO:0031000)2.57915220
146DNA deamination (GO:0045006)2.54513932
147thyroid hormone generation (GO:0006590)2.54179014
148determination of left/right symmetry (GO:0007368)2.52856172
149nucleoside diphosphate phosphorylation (GO:0006165)2.51607891
150relaxation of smooth muscle (GO:0044557)2.49432053
151peptidyl-glutamic acid modification (GO:0018200)2.49174063
152fat-soluble vitamin catabolic process (GO:0042363)2.48400908
153vitamin catabolic process (GO:0009111)2.48400908
154establishment of protein localization to Golgi (GO:0072600)2.47861502
155positive regulation of steroid hormone secretion (GO:2000833)2.46697212
156negative regulation of cyclase activity (GO:0031280)2.45620862
157glycine transport (GO:0015816)2.43997209
158G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.43365680
159DNA alkylation (GO:0006305)2.37112384
160DNA methylation (GO:0006306)2.37112384
161regulation of podosome assembly (GO:0071801)2.32289623
162gene silencing (GO:0016458)2.30756885
163single strand break repair (GO:0000012)2.29571591
164nucleus organization (GO:0006997)2.28703694
165mitotic sister chromatid cohesion (GO:0007064)2.27129744
166regulation of acrosome reaction (GO:0060046)2.25029933
167peptidyl-threonine dephosphorylation (GO:0035970)2.24785634
168protein refolding (GO:0042026)2.20907747
169fusion of sperm to egg plasma membrane (GO:0007342)15.4617660
170cilium or flagellum-dependent cell motility (GO:0001539)15.0825932
171cell wall macromolecule metabolic process (GO:0044036)14.5083310
172cell wall macromolecule catabolic process (GO:0016998)14.5083310
173multicellular organism reproduction (GO:0032504)12.2669443
174acrosome assembly (GO:0001675)12.0812565
175plasma membrane fusion (GO:0045026)11.7525144
176sperm-egg recognition (GO:0035036)11.4043343
177sperm motility (GO:0030317)10.6400335
178cell-cell recognition (GO:0009988)10.3452166
179axonemal dynein complex assembly (GO:0070286)10.0231040

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.20358248
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.03677040
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.27319047
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.17946175
5EZH2_22144423_ChIP-Seq_EOC_Human4.12718532
6GBX2_23144817_ChIP-Seq_PC3_Human3.60057985
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.93536382
8PCGF2_27294783_Chip-Seq_ESCs_Mouse2.79165488
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.58973990
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.48959751
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.41500747
12RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.33419038
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.22087870
14IGF1R_20145208_ChIP-Seq_DFB_Human2.15856232
15CBX2_27304074_Chip-Seq_ESCs_Mouse2.11577148
16EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.11271173
17KAP1_22055183_ChIP-Seq_ESCs_Mouse2.05027391
18P300_19829295_ChIP-Seq_ESCs_Human2.02699684
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.01553827
20* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.97972029
21NFE2_27457419_Chip-Seq_LIVER_Mouse1.95957459
22VDR_22108803_ChIP-Seq_LS180_Human1.93779641
23SUZ12_27294783_Chip-Seq_NPCs_Mouse1.93233751
24BCAT_22108803_ChIP-Seq_LS180_Human1.93203076
25PCGF2_27294783_Chip-Seq_NPCs_Mouse1.91627481
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.88063406
27ZFP57_27257070_Chip-Seq_ESCs_Mouse1.87576981
28STAT1_17558387_ChIP-Seq_HELA_Human1.87367515
29GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.84413944
30ZNF274_21170338_ChIP-Seq_K562_Hela1.80023312
31STAT3_23295773_ChIP-Seq_U87_Human1.79968695
32CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.77906990
33ELK4_26923725_Chip-Seq_MESODERM_Mouse1.77582668
34KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.75296479
35AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.74898292
36TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.74671045
37SOX2_19829295_ChIP-Seq_ESCs_Human1.74468353
38NANOG_19829295_ChIP-Seq_ESCs_Human1.74468353
39TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.70679289
40CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.69475891
41KDM2B_26808549_Chip-Seq_REH_Human1.69036292
42SMAD4_21799915_ChIP-Seq_A2780_Human1.68038156
43TAL1_26923725_Chip-Seq_HPCs_Mouse1.64612442
44UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.62142605
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61798551
46EZH2_27294783_Chip-Seq_NPCs_Mouse1.60493140
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60087441
48GATA1_26923725_Chip-Seq_HPCs_Mouse1.59841222
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.59370092
50CRX_20693478_ChIP-Seq_RETINA_Mouse1.58027981
51EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.57232294
52ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.56209141
53RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.56034392
54EWS_26573619_Chip-Seq_HEK293_Human1.55255409
55NANOG_18555785_Chip-Seq_ESCs_Mouse1.53034042
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.52714055
57MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.51902513
58AR_25329375_ChIP-Seq_VCAP_Human1.51344711
59PIAS1_25552417_ChIP-Seq_VCAP_Human1.49733096
60P53_22387025_ChIP-Seq_ESCs_Mouse1.49006185
61OCT4_18555785_Chip-Seq_ESCs_Mouse1.47492265
62GATA3_21867929_ChIP-Seq_CD8_Mouse1.47485435
63EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.47409757
64GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.46085360
65RXR_22108803_ChIP-Seq_LS180_Human1.45875464
66WDR5_24793694_ChIP-Seq_LNCAP_Human1.45597197
67TOP2B_26459242_ChIP-Seq_MCF-7_Human1.44796426
68CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.44297234
69ESRRB_18555785_Chip-Seq_ESCs_Mouse1.43041730
70KLF4_18555785_Chip-Seq_ESCs_Mouse1.42727766
71CMYC_18555785_Chip-Seq_ESCs_Mouse1.42400586
72P300_18555785_Chip-Seq_ESCs_Mouse1.40812045
73RUNX2_22187159_ChIP-Seq_PCA_Human1.38927137
74SUZ12_18555785_Chip-Seq_ESCs_Mouse1.38489173
75NR3C1_21868756_ChIP-Seq_MCF10A_Human1.38184706
76IRF1_19129219_ChIP-ChIP_H3396_Human1.37852506
77BP1_19119308_ChIP-ChIP_Hs578T_Human1.37807248
78STAT3_18555785_Chip-Seq_ESCs_Mouse1.37233259
79HTT_18923047_ChIP-ChIP_STHdh_Human1.35699272
80CTBP2_25329375_ChIP-Seq_LNCAP_Human1.34544255
81CBP_20019798_ChIP-Seq_JUKART_Human1.34155934
82IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.34155934
83RUNX1_27457419_Chip-Seq_LIVER_Mouse1.33547086
84CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33421907
85OCT4_21477851_ChIP-Seq_ESCs_Mouse1.33115158
86FLI1_21867929_ChIP-Seq_TH2_Mouse1.32041308
87RNF2_27304074_Chip-Seq_NSC_Mouse1.30838145
88PRDM14_20953172_ChIP-Seq_ESCs_Human1.30192470
89GF1_26923725_Chip-Seq_HPCs_Mouse1.30140310
90TCF4_22108803_ChIP-Seq_LS180_Human1.28175628
91MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.27616302
92MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.27578745
93CTCF_18555785_Chip-Seq_ESCs_Mouse1.25643485
94RUNX1_26923725_Chip-Seq_HPCs_Mouse1.25353383
95GATA3_21867929_ChIP-Seq_TH1_Mouse1.25122896
96SOX2_18555785_Chip-Seq_ESCs_Mouse1.25094125
97CDX2_22108803_ChIP-Seq_LS180_Human1.24047224
98SOX2_21211035_ChIP-Seq_LN229_Gbm1.23363127
99E2F1_18555785_Chip-Seq_ESCs_Mouse1.23121192
100PU1_27457419_Chip-Seq_LIVER_Mouse1.21795990
101TP53_22573176_ChIP-Seq_HFKS_Human1.21768674
102OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21487036
103NMYC_18555785_Chip-Seq_ESCs_Mouse1.21152421
104LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.20854773
105FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20687974
106ZFX_18555785_Chip-Seq_ESCs_Mouse1.20517746
107SMAD1_18555785_Chip-Seq_ESCs_Mouse1.18153029
108KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17732169
109TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.17508745
110REST_21632747_ChIP-Seq_MESCs_Mouse1.17361971
111SMAD4_21741376_ChIP-Seq_EPCs_Human1.17056355
112BMI1_23680149_ChIP-Seq_NPCS_Mouse1.15517143
113GATA3_21878914_ChIP-Seq_MCF-7_Human1.14571936
114CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14294875
115TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14123875
116SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13705552
117SOX2_22085726_ChIP-Seq_NPCs_Mouse1.13539512
118TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11776573
119NANOG_20526341_ChIP-Seq_ESCs_Human1.10981044
120TAF15_26573619_Chip-Seq_HEK293_Human1.09087315
121SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.09038788
122AR_21572438_ChIP-Seq_LNCaP_Human1.07661168
123EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07089228
124STAT6_21828071_ChIP-Seq_BEAS2B_Human1.05767203
125MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.05571564
126SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.05257021
127CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02590369
128PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.01576881
129VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.01258689
130SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.00317230
131ARNT_22903824_ChIP-Seq_MCF-7_Human0.99965901
132FOXA1_21572438_ChIP-Seq_LNCaP_Human0.99930671
133PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.99065051
134TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.98990987
135POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.98174643
136TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98174643
137BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97392751
138RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.97303162
139GF1B_26923725_Chip-Seq_HPCs_Mouse0.95898106
140AR_20517297_ChIP-Seq_VCAP_Human0.94886837
141FUS_26573619_Chip-Seq_HEK293_Human0.94835173
142TP53_18474530_ChIP-ChIP_U2OS_Human0.94723249
143DROSHA_22980978_ChIP-Seq_HELA_Human0.94659961
144NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.94198638
145P53_21459846_ChIP-Seq_SAOS-2_Human0.94086360
146SMAD4_21741376_ChIP-Seq_HESCs_Human0.94063369
147ESET_19884257_ChIP-Seq_ESCs_Mouse0.93759009
148SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.93346408
149SALL1_21062744_ChIP-ChIP_HESCs_Human0.92458097
150OCT1_27270436_Chip-Seq_PROSTATE_Human0.92332701
151CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.92316929
152PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91697727
153RAD21_21589869_ChIP-Seq_MESCs_Mouse0.91457834
154ER_23166858_ChIP-Seq_MCF-7_Human0.90341219
155PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90332279
156FLI1_21867929_ChIP-Seq_CD8_Mouse0.88756754
157STAT3_18555785_ChIP-Seq_MESCs_Mouse0.88543365
158LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.88496802
159FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.88337511
160TCF4_23295773_ChIP-Seq_U87_Human0.88258380
161NFYB_21822215_ChIP-Seq_K562_Human0.88133692

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.66131333
2MP0001929_abnormal_gametogenesis5.49035116
3MP0008877_abnormal_DNA_methylation5.45005695
4MP0003195_calcinosis4.20031872
5MP0009780_abnormal_chondrocyte_physiolo3.96558533
6MP0002210_abnormal_sex_determination3.88481904
7MP0002653_abnormal_ependyma_morphology3.71682944
8MP0005360_urolithiasis3.39089483
9MP0001145_abnormal_male_reproductive3.20821868
10MP0001968_abnormal_touch/_nociception3.15203859
11MP0002161_abnormal_fertility/fecundity3.01724068
12MP0000653_abnormal_sex_gland2.85234981
13MP0001501_abnormal_sleep_pattern2.54294830
14MP0008058_abnormal_DNA_repair2.07729157
15MP0005410_abnormal_fertilization14.2490007
16MP0006035_abnormal_mitochondrial_morpho1.96775665
17MP0003880_abnormal_central_pattern1.96774968
18MP0004233_abnormal_muscle_weight1.90190285
19MP0005503_abnormal_tendon_morphology1.87394224
20MP0002272_abnormal_nervous_system1.85893196
21MP0005623_abnormal_meninges_morphology1.74461046
22MP0001664_abnormal_digestion1.74220016
23MP0009046_muscle_twitch1.72225471
24MP0009745_abnormal_behavioral_response1.71130620
25MP0003646_muscle_fatigue1.71095812
26MP0002160_abnormal_reproductive_system1.67298812
27MP0001486_abnormal_startle_reflex1.63487602
28MP0010386_abnormal_urinary_bladder1.59151753
29MP0003950_abnormal_plasma_membrane1.46653973
30MP0005670_abnormal_white_adipose1.44897067
31MP0003283_abnormal_digestive_organ1.44893614
32MP0010094_abnormal_chromosome_stability1.42215119
33MP0008057_abnormal_DNA_replication1.40196378
34MP0001986_abnormal_taste_sensitivity1.38324236
35MP0002733_abnormal_thermal_nociception1.35221059
36MP0001984_abnormal_olfaction1.34849507
37MP0003718_maternal_effect1.34692190
38MP0006276_abnormal_autonomic_nervous1.33013063
39MP0002102_abnormal_ear_morphology1.31778176
40MP0004134_abnormal_chest_morphology1.27269511
41MP0003011_delayed_dark_adaptation1.24322365
42MP0001970_abnormal_pain_threshold1.22640240
43MP0002234_abnormal_pharynx_morphology1.18819540
44MP0000383_abnormal_hair_follicle1.17096841
45MP0004270_analgesia1.16781051
46MP0002282_abnormal_trachea_morphology1.16568446
47MP0002168_other_aberrant_phenotype1.16547235
48MP0002572_abnormal_emotion/affect_behav1.15115696
49MP0001529_abnormal_vocalization1.14616030
50MP0000678_abnormal_parathyroid_gland1.13873156
51MP0000230_abnormal_systemic_arterial1.12790347
52MP0001765_abnormal_ion_homeostasis1.09155887
53MP0002064_seizures1.07165650
54MP0000631_abnormal_neuroendocrine_gland1.05853711
55MP0005395_other_phenotype1.05149733
56MP0003635_abnormal_synaptic_transmissio1.04901671
57MP0002928_abnormal_bile_duct1.03786345
58MP0005167_abnormal_blood-brain_barrier1.02753271
59MP0008872_abnormal_physiological_respon1.02234819
60MP0010678_abnormal_skin_adnexa1.00916294
61MP0000681_abnormal_thyroid_gland1.00750105
62MP0005647_abnormal_sex_gland1.00100820
63MP0005389_reproductive_system_phenotype0.99442802
64MP0004147_increased_porphyrin_level0.98224506
65MP0002063_abnormal_learning/memory/cond0.98037006
66MP0004043_abnormal_pH_regulation0.97224689
67MP0003631_nervous_system_phenotype0.96818447
68MP0002229_neurodegeneration0.90619736
69MP0003787_abnormal_imprinting0.90468207
70MP0002067_abnormal_sensory_capabilities0.88681098
71MP0003890_abnormal_embryonic-extraembry0.87003217
72MP0000569_abnormal_digit_pigmentation0.86919276
73MP0001270_distended_abdomen0.84736748
74MP0005386_behavior/neurological_phenoty0.83785292
75MP0004924_abnormal_behavior0.83785292
76MP0008775_abnormal_heart_ventricle0.82863672
77MP0002638_abnormal_pupillary_reflex0.82056057
78MP0005195_abnormal_posterior_eye0.80964414
79MP0002734_abnormal_mechanical_nocicepti0.80426613
80MP0004142_abnormal_muscle_tone0.79626206
81MP0001756_abnormal_urination0.78736937
82MP0008995_early_reproductive_senescence0.76684048
83MP0003567_abnormal_fetal_cardiomyocyte0.76353795
84MP0005332_abnormal_amino_acid0.76020979
85MP0005174_abnormal_tail_pigmentation0.75353707
86MP0003959_abnormal_lean_body0.74337542
87MP0004085_abnormal_heartbeat0.73818835
88MP0004782_abnormal_surfactant_physiolog0.73754606
89MP0002249_abnormal_larynx_morphology0.72693711
90MP0003937_abnormal_limbs/digits/tail_de0.72574591
91MP0003119_abnormal_digestive_system0.72039274
92MP0004133_heterotaxia0.71931329
93MP0004084_abnormal_cardiac_muscle0.71746390
94MP0001545_abnormal_hematopoietic_system0.67681284
95MP0005397_hematopoietic_system_phenotyp0.67681284
96MP0005645_abnormal_hypothalamus_physiol0.67211515
97MP0003786_premature_aging0.65853287
98MP0005646_abnormal_pituitary_gland0.65651678
99MP0005253_abnormal_eye_physiology0.64832531
100MP0000685_abnormal_immune_system0.64013002
101MP0001119_abnormal_female_reproductive0.63514612
102MP0006072_abnormal_retinal_apoptosis0.63026739
103MP0000427_abnormal_hair_cycle0.62383567
104MP0005451_abnormal_body_composition0.60007216
105MP0009278_abnormal_bone_marrow0.59086843
106MP0002132_abnormal_respiratory_system0.55481420
107MP0002009_preneoplasia0.55161237
108MP0002822_catalepsy0.54283220
109MP0002971_abnormal_brown_adipose0.52474979
110MP0004808_abnormal_hematopoietic_stem0.52203154
111MP0001764_abnormal_homeostasis0.50786483
112MP0005551_abnormal_eye_electrophysiolog0.50756843
113MP0002735_abnormal_chemical_nociception0.49846369
114MP0009697_abnormal_copulation0.49637025
115MP0002405_respiratory_system_inflammati0.47263243
116MP0004019_abnormal_vitamin_homeostasis0.46136370
117MP0005636_abnormal_mineral_homeostasis0.45679344
118MP0001188_hyperpigmentation0.45402443
119MP0002876_abnormal_thyroid_physiology0.43660591
120MP0008007_abnormal_cellular_replicative0.43366347
121MP0003699_abnormal_female_reproductive0.42480355
122MP0009115_abnormal_fat_cell0.39597356
123MP0003879_abnormal_hair_cell0.39416353
124MP0001661_extended_life_span0.36752103
125MP0003724_increased_susceptibility_to0.36550232
126MP0002006_tumorigenesis0.36383366
127MP0001835_abnormal_antigen_presentation0.36098356
128MP0010307_abnormal_tumor_latency0.35290707
129MP0005535_abnormal_body_temperature0.34035950
130MP0000432_abnormal_head_morphology0.33051899
131MP0005409_darkened_coat_color0.32909210
132MP0003763_abnormal_thymus_physiology0.32818397
133MP0001963_abnormal_hearing_physiology0.31112790
134MP0000313_abnormal_cell_death0.30414604
135MP0003111_abnormal_nucleus_morphology0.29928800
136MP0002115_abnormal_skeleton_extremities0.29471213
137MP0001919_abnormal_reproductive_system0.29237573
138MP0003045_fibrosis0.29160989
139MP0002109_abnormal_limb_morphology0.29140148
140MP0005084_abnormal_gallbladder_morpholo0.28861281
141MP0000015_abnormal_ear_pigmentation0.28365238
142MP0003633_abnormal_nervous_system0.27338558
143MP0000462_abnormal_digestive_system0.26758189
144MP0002269_muscular_atrophy0.25680016
145MP0003183_abnormal_peptide_metabolism0.25608866
146MP0002557_abnormal_social/conspecific_i0.25603952
147MP0001944_abnormal_pancreas_morphology0.25444232
148MP0000358_abnormal_cell_content/0.25425805
149MP0001851_eye_inflammation0.25254181
150MP0002723_abnormal_immune_serum0.24823658
151MP0006054_spinal_hemorrhage0.24717018
152MP0000026_abnormal_inner_ear0.23440372
153MP0009764_decreased_sensitivity_to0.23173834
154MP0000647_abnormal_sebaceous_gland0.22719258
155MP0005025_abnormal_response_to0.22454599
156MP0002693_abnormal_pancreas_physiology0.21901645
157MP0000579_abnormal_nail_morphology0.21873442
158MP0005391_vision/eye_phenotype0.21239317
159MP0005310_abnormal_salivary_gland0.20134784
160MP0009250_abnormal_appendicular_skeleto0.18453831

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.23837158
2Thyroid-stimulating hormone excess (HP:0002925)9.17533739
3Abnormal respiratory epithelium morphology (HP:0012253)8.50003356
4Abnormal respiratory motile cilium morphology (HP:0005938)8.50003356
5Rhinitis (HP:0012384)7.79541086
6Abnormal ciliary motility (HP:0012262)7.54067794
7Chronic bronchitis (HP:0004469)7.06145325
8Nasal polyposis (HP:0100582)6.34185248
9Intestinal atresia (HP:0011100)6.28751818
10Infertility (HP:0000789)5.65251307
11Abnormality of the nasal mucosa (HP:0000433)5.09562356
12Volvulus (HP:0002580)4.82899954
13Pancreatic islet-cell hyperplasia (HP:0004510)4.80610162
14Bronchiectasis (HP:0002110)4.54844973
15Bronchitis (HP:0012387)4.35273650
16Large for gestational age (HP:0001520)4.22580946
17Gaze-evoked nystagmus (HP:0000640)4.17613287
18Broad alveolar ridges (HP:0000187)4.01621540
19Nephronophthisis (HP:0000090)3.84714923
20Abnormality of the aortic arch (HP:0012303)3.84342087
21Medial flaring of the eyebrow (HP:0010747)3.84231459
22Focal motor seizures (HP:0011153)3.82461803
23Recurrent sinusitis (HP:0011108)3.70769463
24Type II lissencephaly (HP:0007260)3.40098213
25Abnormality of the pancreatic islet cells (HP:0006476)3.30538346
26Abnormality of endocrine pancreas physiology (HP:0012093)3.30538346
27Agitation (HP:0000713)3.29476639
28Gastrointestinal atresia (HP:0002589)3.26941145
29Recurrent otitis media (HP:0000403)3.20362310
30Progressive inability to walk (HP:0002505)3.11380449
31Tented upper lip vermilion (HP:0010804)3.01155535
32Congenital primary aphakia (HP:0007707)3.00296219
33Gait imbalance (HP:0002141)2.99192018
34Abnormal spermatogenesis (HP:0008669)2.97994704
35Thickened helices (HP:0000391)2.97327524
36Attenuation of retinal blood vessels (HP:0007843)2.97309267
37Poor head control (HP:0002421)2.96255041
38Abnormality of the renal medulla (HP:0100957)2.94510043
39Oligodontia (HP:0000677)2.89083405
40Male infertility (HP:0003251)2.86476787
41Abnormality of the ileum (HP:0001549)2.83920301
42Congenital stationary night blindness (HP:0007642)2.80122029
43Broad-based gait (HP:0002136)2.72169359
44Azoospermia (HP:0000027)2.70850402
45Optic nerve hypoplasia (HP:0000609)2.67096430
46Nephrogenic diabetes insipidus (HP:0009806)2.60095669
47Abnormality of macular pigmentation (HP:0008002)2.57496158
48Lissencephaly (HP:0001339)2.56184206
49Recurrent bronchitis (HP:0002837)2.54692533
50Gonadotropin excess (HP:0000837)2.53744677
51Abnormality of midbrain morphology (HP:0002418)2.53531973
52Molar tooth sign on MRI (HP:0002419)2.53531973
53Chronic sinusitis (HP:0011109)2.51862425
54Increased corneal curvature (HP:0100692)2.51113488
55Keratoconus (HP:0000563)2.51113488
56Central scotoma (HP:0000603)2.48706909
57Inability to walk (HP:0002540)2.46481972
58Chronic hepatic failure (HP:0100626)2.45130810
59Tubulointerstitial nephritis (HP:0001970)2.42792900
60Focal seizures (HP:0007359)2.40572876
61Dysdiadochokinesis (HP:0002075)2.37722014
62Mesangial abnormality (HP:0001966)2.36992784
63Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.34198027
64Fibular hypoplasia (HP:0003038)2.33984453
65Dialeptic seizures (HP:0011146)2.25883589
66Poor coordination (HP:0002370)2.25344465
67Abnormality of the pons (HP:0007361)2.23687476
68Hypoplasia of the pons (HP:0012110)2.21676318
69Postaxial foot polydactyly (HP:0001830)2.20714214
70Hypophosphatemic rickets (HP:0004912)2.12955039
71Abolished electroretinogram (ERG) (HP:0000550)2.11935807
72Amyotrophic lateral sclerosis (HP:0007354)2.11748287
73Hyperpituitarism (HP:0010514)2.10707543
74Tongue fasciculations (HP:0001308)2.06119525
75Genital tract atresia (HP:0001827)2.06118616
76Vaginal atresia (HP:0000148)2.05120925
77Aplasia/Hypoplasia of the lens (HP:0008063)2.04506785
78Progressive cerebellar ataxia (HP:0002073)2.04359489
79Short ribs (HP:0000773)2.03103912
80Facial cleft (HP:0002006)2.00851491
81Bony spicule pigmentary retinopathy (HP:0007737)2.00708983
82Genetic anticipation (HP:0003743)2.00615652
83Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.4332066
84Absent/shortened dynein arms (HP:0200106)11.8451061
85Dynein arm defect of respiratory motile cilia (HP:0012255)11.8451061
86Male pseudohermaphroditism (HP:0000037)1.99938386
87Abnormality of the lower motor neuron (HP:0002366)1.99934816
88Pendular nystagmus (HP:0012043)1.99213036
89Ketosis (HP:0001946)1.99070199
90Tubulointerstitial abnormality (HP:0001969)1.98181686
91Abnormal rod and cone electroretinograms (HP:0008323)1.97821553
92Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.97625192
93Absent epiphyses (HP:0010577)1.97625192
94Abnormality of the renal cortex (HP:0011035)1.95617267
95Congenital ichthyosiform erythroderma (HP:0007431)1.95406276
96Congenital hepatic fibrosis (HP:0002612)1.95263872
97Abnormal biliary tract physiology (HP:0012439)1.95099995
98Bile duct proliferation (HP:0001408)1.95099995
99Hypoproteinemia (HP:0003075)1.94901451
100Scotoma (HP:0000575)1.92650829
101Absent speech (HP:0001344)1.91893712
102Muscle fibrillation (HP:0010546)1.91612967
103Anencephaly (HP:0002323)1.90576855
104Postaxial hand polydactyly (HP:0001162)1.88440976
105Hypoplasia of the capital femoral epiphysis (HP:0003090)1.87725452
106Severe visual impairment (HP:0001141)1.87483787
107Protruding tongue (HP:0010808)1.86847478
108Tubular atrophy (HP:0000092)1.86505187
109Bilateral microphthalmos (HP:0007633)1.84724427
110Decreased circulating renin level (HP:0003351)1.84292822
111Amelogenesis imperfecta (HP:0000705)1.82971694
112Febrile seizures (HP:0002373)1.82793691
113Poor speech (HP:0002465)1.82638335
114Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.81874608
115Hyperventilation (HP:0002883)1.81068096
116Hypothermia (HP:0002045)1.80710751
117Abnormality of the alveolar ridges (HP:0006477)1.79961530
118Ketoacidosis (HP:0001993)1.78803703
119Aplasia/Hypoplasia of the uvula (HP:0010293)1.77358000
120Chromosomal breakage induced by crosslinking agents (HP:0003221)1.75848435
121Easy fatigability (HP:0003388)1.73774516
122Short thorax (HP:0010306)1.73271875
123Facial diplegia (HP:0001349)1.73211056
124Absent frontal sinuses (HP:0002688)1.72327376
125Polyuria (HP:0000103)1.72010329
126Aplasia/Hypoplasia of the brainstem (HP:0007362)1.71262443
127Hypoplasia of the brainstem (HP:0002365)1.71262443
128Occipital encephalocele (HP:0002085)1.70834076
129Microglossia (HP:0000171)1.70419091
130Chronic otitis media (HP:0000389)1.69937239
131Stage 5 chronic kidney disease (HP:0003774)1.66990231
132Pancreatic fibrosis (HP:0100732)1.66663760
133Short femoral neck (HP:0100864)1.63325404
134Fatigue (HP:0012378)1.62669535
135Impulsivity (HP:0100710)1.60765651
136Median cleft lip (HP:0000161)1.60417563
137Abnormality of ocular smooth pursuit (HP:0000617)1.59223207
138Abnormality of saccadic eye movements (HP:0000570)1.58663341
139Type 2 muscle fiber atrophy (HP:0003554)1.56552109
140Aplasia/Hypoplasia of the tongue (HP:0010295)1.53078071
141Nonprogressive disorder (HP:0003680)1.50771255
142Oculomotor apraxia (HP:0000657)1.50746171
143Tubulointerstitial fibrosis (HP:0005576)1.49977664
144Cystic liver disease (HP:0006706)1.49729977
145Renal dysplasia (HP:0000110)1.47244748
146Aplasia/Hypoplasia of the fibula (HP:0006492)1.47233808
147Supernumerary spleens (HP:0009799)1.46894302
148Abnormal drinking behavior (HP:0030082)1.46785726
149Polydipsia (HP:0001959)1.46785726
150Abnormality of the neuromuscular junction (HP:0003398)1.44679708
151Fatigable weakness (HP:0003473)1.44679708
152Abnormality of permanent molar morphology (HP:0011071)1.44505383
153Abnormality of the dental root (HP:0006486)1.44505383
154Taurodontia (HP:0000679)1.44505383
155Broad foot (HP:0001769)1.44037111
156True hermaphroditism (HP:0010459)1.43805320
157Breast carcinoma (HP:0003002)1.41379660
158Decreased central vision (HP:0007663)1.40054776
159Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.39661609
160Abnormality of molar morphology (HP:0011070)1.35896722
161Abnormality of molar (HP:0011077)1.35896722
162Impaired proprioception (HP:0010831)1.35476485
163Pancreatic cysts (HP:0001737)1.34987310
164Nephropathy (HP:0000112)1.34330302
16511 pairs of ribs (HP:0000878)1.34211285
166Irregular epiphyses (HP:0010582)1.31318405
167Dental crowding (HP:0000678)1.29223602
168Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.28359082
169Cerebellar dysplasia (HP:0007033)1.28195578
170J-shaped sella turcica (HP:0002680)1.27480212
171Abnormality of dentin (HP:0010299)1.26468081
172Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.26378114
173Abnormality of the epiphysis of the femoral head (HP:0010574)1.25711481

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK48.73615403
2PDK38.73615403
3PDK25.75312669
4TESK13.88418964
5MAP4K23.29021531
6ICK3.05147390
7PRKD33.03998912
8WNK42.34548086
9STK392.29625393
10ACVR1B2.22502226
11NTRK32.18434267
12PTK2B2.10376635
13INSRR1.90264059
14ADRBK11.87725177
15STK161.70400715
16CASK1.63506468
17GRK11.58658225
18ERN11.57733554
19TGFBR11.53216254
20PLK41.51770117
21NUAK11.50422603
22NEK21.47778939
23STK381.47688905
24PNCK1.46944324
25PRKCE1.40578949
26IRAK11.38694587
27TLK11.32586452
28TAOK31.25891017
29CCNB11.24978658
30MAPK131.22852244
31STK31.21309332
32CAMKK21.19182582
33CHEK21.14100611
34RIPK41.12679215
35PASK1.09229786
36CDK121.07893314
37PDK11.02925629
38BRSK20.98271861
39TTK0.95362022
40DAPK20.95207320
41STK38L0.89571892
42PLK20.88564490
43DYRK1B0.84320336
44CAMK2A0.84219727
45BRD40.83260985
46TRIM280.81729747
47CSNK1A1L0.81008485
48RIPK10.80184416
49OXSR10.76183129
50WNK10.75338394
51TYRO30.74089775
52TIE10.73989782
53MAPK150.73415896
54CSNK1G30.73276800
55PIK3CG0.72120777
56YES10.71699412
57RPS6KA50.69536687
58PKN20.69128757
59MKNK20.65427927
60CSNK1G20.65359946
61LMTK20.64633937
62PINK10.62994001
63CSNK1G10.61833560
64MAPK110.61484182
65MAP3K90.58823044
66ZAP700.58639529
67MAP2K60.57053241
68MAP3K120.56904807
69TEC0.56288900
70CDC70.55942307
71GRK70.55720705
72CAMK10.54705810
73DYRK30.53481499
74MKNK10.53319321
75FLT30.52230343
76EEF2K0.51741327
77BCR0.51210379
78CHEK10.50806889
79MAP2K70.49763829
80GRK50.46086263
81NLK0.45578026
82ATR0.45504479
83NEK60.43167066
84TNIK0.41724230
85MUSK0.41666889
86ADRBK20.41282356
87LATS10.39975489
88PRKG20.39096542
89ERBB20.38829709
90DYRK1A0.38319069
91IRAK20.37433028
92PHKG10.37407097
93PHKG20.37407097
94PAK30.37039953
95CAMKK10.35703358
96BCKDK0.35115030
97PRKCI0.34541535
98CSNK1A10.34245522
99MAPKAPK30.33791897
100MAP2K20.33150840
101MAPK70.33118449
102ATM0.33036392
103MET0.32507378
104MAPKAPK50.31927899
105KIT0.31795388
106CAMK40.31320685
107PDPK10.30117774
108PRKCB0.30048944
109PLK10.29992657
110BRSK10.29818234
111PRKACA0.29701787
112FRK0.29587473
113BMPR1B0.28536033
114WEE10.28505550
115RPS6KA30.27972163
116CHUK0.27576766
117TESK20.27499249
118PRKCH0.27340327
119CSK0.27001150
120AKT30.26575756
121OBSCN0.26388372
122VRK10.26105444
123MAPK10.25772402
124SGK10.24778312
125PRKACB0.24484383
126IGF1R0.24267402
127CDK90.23819645
128DDR20.23768559
129TXK0.23674730
130BMPR20.22451871
131CLK10.21943622
132ZAK0.21410639
133PDGFRB0.21262100
134STK110.20333970
135EIF2AK30.20230896
136WNK30.18423411
137CSF1R0.17084372
138PAK10.16649088
139RPS6KB10.16537851
140MYLK0.16500483
141PRKG10.14055011
142PRKCG0.14030966
143EGFR0.13411115
144PKN10.12339522
145PRKCQ0.11089762
146MARK20.10514355
147TBK10.08969803
148MAP3K40.08698394
149NTRK20.08327900
150MARK30.08205516
151CAMK1G0.07949228
152CDK70.07757517
153MAP3K60.07355219
154SYK0.07067561
155CSNK2A10.06495751
156STK40.06489993
157PRKCA0.06417857
158CSNK2A20.06098403
159BTK0.05981591
160CDK30.04587952
161CDK40.04308611
162PAK20.04249690
163PRKAA10.03680116
164ABL10.03330859

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.72324591
2Basal transcription factors_Homo sapiens_hsa030224.13918813
3Pentose phosphate pathway_Homo sapiens_hsa000303.53122803
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.47748846
5Pyruvate metabolism_Homo sapiens_hsa006203.31654858
6Fanconi anemia pathway_Homo sapiens_hsa034603.31284122
7Selenocompound metabolism_Homo sapiens_hsa004503.28968767
8Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.22498842
9Olfactory transduction_Homo sapiens_hsa047403.20850410
10Propanoate metabolism_Homo sapiens_hsa006402.79184026
11Phototransduction_Homo sapiens_hsa047442.53699662
12Butanoate metabolism_Homo sapiens_hsa006502.51586686
13Glucagon signaling pathway_Homo sapiens_hsa049222.37563383
14Fatty acid biosynthesis_Homo sapiens_hsa000612.30777548
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.25497135
16Linoleic acid metabolism_Homo sapiens_hsa005912.17905194
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.15419330
18Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.14785040
19Morphine addiction_Homo sapiens_hsa050322.03625079
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.92747680
21Dorso-ventral axis formation_Homo sapiens_hsa043201.92595415
22Cyanoamino acid metabolism_Homo sapiens_hsa004601.92030907
23Oocyte meiosis_Homo sapiens_hsa041141.78245870
24Glycosaminoglycan degradation_Homo sapiens_hsa005311.76165909
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.75014497
26Nitrogen metabolism_Homo sapiens_hsa009101.72901050
27Tryptophan metabolism_Homo sapiens_hsa003801.72541245
28Amphetamine addiction_Homo sapiens_hsa050311.69666284
29Glycerolipid metabolism_Homo sapiens_hsa005611.68573115
30Huntingtons disease_Homo sapiens_hsa050161.67048447
31Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.61561232
32Nicotine addiction_Homo sapiens_hsa050331.59080344
33Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.54003759
34Ovarian steroidogenesis_Homo sapiens_hsa049131.52258906
35Antigen processing and presentation_Homo sapiens_hsa046121.46019026
36Graft-versus-host disease_Homo sapiens_hsa053321.39788611
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.39777202
38N-Glycan biosynthesis_Homo sapiens_hsa005101.36659791
39Purine metabolism_Homo sapiens_hsa002301.32287388
40Intestinal immune network for IgA production_Homo sapiens_hsa046721.31620602
41Ether lipid metabolism_Homo sapiens_hsa005651.30815731
42Carbohydrate digestion and absorption_Homo sapiens_hsa049731.27977003
43mRNA surveillance pathway_Homo sapiens_hsa030151.26394671
44Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.22965391
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.21909896
46Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.18773586
47Renin secretion_Homo sapiens_hsa049241.18048557
48Glutamatergic synapse_Homo sapiens_hsa047241.17258784
49Asthma_Homo sapiens_hsa053101.16911547
50Salivary secretion_Homo sapiens_hsa049701.14935168
51beta-Alanine metabolism_Homo sapiens_hsa004101.12183970
52Legionellosis_Homo sapiens_hsa051341.06574666
53RNA transport_Homo sapiens_hsa030131.01505894
54Systemic lupus erythematosus_Homo sapiens_hsa053220.99078647
55Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.97787051
56GABAergic synapse_Homo sapiens_hsa047270.97185301
57Renin-angiotensin system_Homo sapiens_hsa046140.97116426
58Serotonergic synapse_Homo sapiens_hsa047260.96750052
59Cysteine and methionine metabolism_Homo sapiens_hsa002700.96351454
60Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.93481885
61Histidine metabolism_Homo sapiens_hsa003400.92512900
62PPAR signaling pathway_Homo sapiens_hsa033200.91910739
63Homologous recombination_Homo sapiens_hsa034400.89471677
64Glycerophospholipid metabolism_Homo sapiens_hsa005640.87161835
65Protein export_Homo sapiens_hsa030600.86619621
66Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.84875455
67Carbon metabolism_Homo sapiens_hsa012000.82302825
68Calcium signaling pathway_Homo sapiens_hsa040200.81193607
69Maturity onset diabetes of the young_Homo sapiens_hsa049500.80176508
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.80093142
71ABC transporters_Homo sapiens_hsa020100.79558534
72Salmonella infection_Homo sapiens_hsa051320.79399503
73Regulation of autophagy_Homo sapiens_hsa041400.78425447
74Long-term depression_Homo sapiens_hsa047300.77985695
75Type I diabetes mellitus_Homo sapiens_hsa049400.76838508
76Peroxisome_Homo sapiens_hsa041460.75300271
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.74885877
78Fructose and mannose metabolism_Homo sapiens_hsa000510.72058493
79Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.71914533
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.71807127
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70025601
82Protein digestion and absorption_Homo sapiens_hsa049740.68744608
83Non-homologous end-joining_Homo sapiens_hsa034500.68691212
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.68469824
85Long-term potentiation_Homo sapiens_hsa047200.68438178
86Insulin secretion_Homo sapiens_hsa049110.68010177
87B cell receptor signaling pathway_Homo sapiens_hsa046620.67957538
88Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.67938958
89Autoimmune thyroid disease_Homo sapiens_hsa053200.67328638
90SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66757458
91Starch and sucrose metabolism_Homo sapiens_hsa005000.66605586
92Allograft rejection_Homo sapiens_hsa053300.66509618
93RNA degradation_Homo sapiens_hsa030180.64825595
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.64378599
95Vascular smooth muscle contraction_Homo sapiens_hsa042700.64246916
96Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63265233
97Primary immunodeficiency_Homo sapiens_hsa053400.62388606
98p53 signaling pathway_Homo sapiens_hsa041150.62056759
99Pancreatic secretion_Homo sapiens_hsa049720.61638855
100Mineral absorption_Homo sapiens_hsa049780.61265956
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.60030856
102Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.57642759
103Oxytocin signaling pathway_Homo sapiens_hsa049210.57133285
104Primary bile acid biosynthesis_Homo sapiens_hsa001200.55197496
105Taste transduction_Homo sapiens_hsa047420.54766441
106Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.54732434
107Inositol phosphate metabolism_Homo sapiens_hsa005620.54011706
108cGMP-PKG signaling pathway_Homo sapiens_hsa040220.53901649
109Dopaminergic synapse_Homo sapiens_hsa047280.53481557
110Fat digestion and absorption_Homo sapiens_hsa049750.53111904
111Biosynthesis of amino acids_Homo sapiens_hsa012300.51746659
112One carbon pool by folate_Homo sapiens_hsa006700.49533929
113Cardiac muscle contraction_Homo sapiens_hsa042600.48509891
114Estrogen signaling pathway_Homo sapiens_hsa049150.47161451
115Caffeine metabolism_Homo sapiens_hsa002320.46817843
116Pyrimidine metabolism_Homo sapiens_hsa002400.46447849
117Arachidonic acid metabolism_Homo sapiens_hsa005900.44192411
118Cocaine addiction_Homo sapiens_hsa050300.44123100
119Gap junction_Homo sapiens_hsa045400.43935486
120Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.42293591
121Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.41948049
122Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41605614
123Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.41443029
124Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40714017
125Sphingolipid metabolism_Homo sapiens_hsa006000.38936053
126Collecting duct acid secretion_Homo sapiens_hsa049660.38849896
127Thyroid hormone synthesis_Homo sapiens_hsa049180.38588971
128Circadian rhythm_Homo sapiens_hsa047100.38392672
129Measles_Homo sapiens_hsa051620.37950405
130NF-kappa B signaling pathway_Homo sapiens_hsa040640.37464925
131Arginine biosynthesis_Homo sapiens_hsa002200.36667040
132Glutathione metabolism_Homo sapiens_hsa004800.35000253
133Chemical carcinogenesis_Homo sapiens_hsa052040.34988797
134Retinol metabolism_Homo sapiens_hsa008300.34885375
135Metabolic pathways_Homo sapiens_hsa011000.33333339
136Rheumatoid arthritis_Homo sapiens_hsa053230.33124208
137Synaptic vesicle cycle_Homo sapiens_hsa047210.33086185
138Cell cycle_Homo sapiens_hsa041100.33063643
139Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.32192606
140T cell receptor signaling pathway_Homo sapiens_hsa046600.31631885
141Aldosterone synthesis and secretion_Homo sapiens_hsa049250.31407915
142Wnt signaling pathway_Homo sapiens_hsa043100.30963879
143Viral carcinogenesis_Homo sapiens_hsa052030.30576922
144Herpes simplex infection_Homo sapiens_hsa051680.30015733
145Fatty acid degradation_Homo sapiens_hsa000710.29517662
146Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26799300
147Steroid hormone biosynthesis_Homo sapiens_hsa001400.25790581
148Alcoholism_Homo sapiens_hsa050340.25744296
149Hedgehog signaling pathway_Homo sapiens_hsa043400.25334774
150Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.25191365
151Circadian entrainment_Homo sapiens_hsa047130.24791464
152cAMP signaling pathway_Homo sapiens_hsa040240.24715853

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