STRA13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)7.86136443
2proline biosynthetic process (GO:0006561)6.94321815
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.11315598
4transcription from mitochondrial promoter (GO:0006390)6.08951299
5ATP synthesis coupled proton transport (GO:0015986)5.49783432
6energy coupled proton transport, down electrochemical gradient (GO:0015985)5.49783432
7proline metabolic process (GO:0006560)5.49214433
8telomere maintenance via semi-conservative replication (GO:0032201)5.16181641
9regulation of mitochondrial translation (GO:0070129)4.99016715
10chaperone-mediated protein transport (GO:0072321)4.91053791
11mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.72984117
12formation of translation preinitiation complex (GO:0001731)4.65292141
13viral mRNA export from host cell nucleus (GO:0046784)4.63842712
14protein complex biogenesis (GO:0070271)4.62282635
15respiratory electron transport chain (GO:0022904)4.60599999
16positive regulation of protein homooligomerization (GO:0032464)4.57507291
17electron transport chain (GO:0022900)4.50767750
18telomere maintenance via recombination (GO:0000722)4.46849320
19* replication fork processing (GO:0031297)4.44957163
20mitochondrial respiratory chain complex assembly (GO:0033108)4.41802844
21DNA strand elongation involved in DNA replication (GO:0006271)4.39535570
22embryonic process involved in female pregnancy (GO:0060136)4.39465639
23nucleotide-excision repair, DNA gap filling (GO:0006297)4.26239499
24DNA strand elongation (GO:0022616)4.16414570
25somatic hypermutation of immunoglobulin genes (GO:0016446)4.15091822
26somatic diversification of immune receptors via somatic mutation (GO:0002566)4.15091822
27mitochondrial respiratory chain complex I assembly (GO:0032981)4.13377798
28NADH dehydrogenase complex assembly (GO:0010257)4.13377798
29mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.13377798
30* maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)4.06550173
31negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.02727945
32negative regulation of ligase activity (GO:0051352)4.02727945
33regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.02008918
34protein targeting to mitochondrion (GO:0006626)3.99328201
35positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.98360648
36ribosomal small subunit assembly (GO:0000028)3.97176971
37proteasome assembly (GO:0043248)3.95660777
38oxidative demethylation (GO:0070989)3.90603868
39establishment of protein localization to mitochondrial membrane (GO:0090151)3.89722286
40anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.89187262
41viral transcription (GO:0019083)3.84620004
42mitochondrial DNA metabolic process (GO:0032042)3.83030463
43pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.81970180
44regulation of cellular amino acid metabolic process (GO:0006521)3.81113469
45transcription elongation from RNA polymerase III promoter (GO:0006385)3.80823118
46termination of RNA polymerase III transcription (GO:0006386)3.80823118
47mitotic recombination (GO:0006312)3.76895851
48establishment of protein localization to mitochondrion (GO:0072655)3.74522184
49GDP-mannose metabolic process (GO:0019673)3.73309154
50regulation of double-strand break repair via homologous recombination (GO:0010569)3.71217779
51rRNA modification (GO:0000154)3.68262523
52translational termination (GO:0006415)3.66745040
53pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.65259760
54GTP biosynthetic process (GO:0006183)3.65193357
55telomere maintenance via telomere lengthening (GO:0010833)3.64169931
56DNA replication checkpoint (GO:0000076)3.62001358
57regulation of integrin activation (GO:0033623)3.61780481
58base-excision repair (GO:0006284)3.61194618
59poly(A)+ mRNA export from nucleus (GO:0016973)3.60061893
60signal transduction involved in DNA damage checkpoint (GO:0072422)3.59411986
61protein localization to mitochondrion (GO:0070585)3.58344244
62establishment of integrated proviral latency (GO:0075713)3.57502039
63DNA integration (GO:0015074)3.56919358
64cytochrome complex assembly (GO:0017004)3.56744220
65maturation of 5.8S rRNA (GO:0000460)3.54731752
66base-excision repair, AP site formation (GO:0006285)3.54521153
67signal transduction involved in cell cycle checkpoint (GO:0072395)3.53776078
68ribosomal small subunit biogenesis (GO:0042274)3.53092265
69positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.51836219
70pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.51427121
71regulation of protein homooligomerization (GO:0032462)3.51162441
72mitochondrial RNA metabolic process (GO:0000959)3.49960906
73DNA strand renaturation (GO:0000733)3.48117716
74respiratory chain complex IV assembly (GO:0008535)3.46495753
75cellular component biogenesis (GO:0044085)3.45862765
76guanosine-containing compound biosynthetic process (GO:1901070)3.45542410
77CTP metabolic process (GO:0046036)3.44863370
78CTP biosynthetic process (GO:0006241)3.44863370
79UTP biosynthetic process (GO:0006228)3.44566485
80chromatin remodeling at centromere (GO:0031055)3.43598905
81mitotic G1 DNA damage checkpoint (GO:0031571)3.41663119
82purine nucleoside triphosphate biosynthetic process (GO:0009145)3.41292618
83translational initiation (GO:0006413)3.39004720
84purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.38828239
85cellular response to zinc ion (GO:0071294)3.38701645
86positive regulation of ligase activity (GO:0051351)3.36978053
87translational elongation (GO:0006414)3.35939448
88meiotic chromosome segregation (GO:0045132)3.35524707
89CENP-A containing nucleosome assembly (GO:0034080)3.35299691
90nucleobase-containing small molecule interconversion (GO:0015949)3.32543787
91pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.31095628
92ribonucleoside triphosphate biosynthetic process (GO:0009201)3.30693089
93ATP biosynthetic process (GO:0006754)3.30502412
94termination of RNA polymerase II transcription (GO:0006369)3.28972024
95peptidyl-histidine modification (GO:0018202)3.28483694
96inner mitochondrial membrane organization (GO:0007007)3.27465126
97SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.27102856
98maturation of SSU-rRNA (GO:0030490)3.24201509
99regulation of ubiquitin-protein transferase activity (GO:0051438)3.23978938
100pseudouridine synthesis (GO:0001522)3.22425724
101nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.18852590
102DNA ligation (GO:0006266)3.18707238
103DNA double-strand break processing (GO:0000729)3.18631120
104cotranslational protein targeting to membrane (GO:0006613)3.18056540
105rRNA processing (GO:0006364)3.17386502
106ribosome biogenesis (GO:0042254)3.17138088
107protein targeting to ER (GO:0045047)3.17028144
108protein maturation by protein folding (GO:0022417)3.16865005
109pyrimidine nucleotide catabolic process (GO:0006244)3.15468962
110establishment of apical/basal cell polarity (GO:0035089)3.14699428
111transcription-coupled nucleotide-excision repair (GO:0006283)3.13145790
112ribonucleoprotein complex biogenesis (GO:0022613)3.11990832
113pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.10339495
114double-strand break repair via nonhomologous end joining (GO:0006303)3.03606477
115non-recombinational repair (GO:0000726)3.03606477
116rRNA metabolic process (GO:0016072)3.03532982
117protein localization to endoplasmic reticulum (GO:0070972)3.01178532
118G1 DNA damage checkpoint (GO:0044783)2.99954584
119mitotic G1/S transition checkpoint (GO:0044819)2.99187495
120nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.97282603
121negative regulation of cell cycle arrest (GO:0071157)2.96882119
122viral life cycle (GO:0019058)2.96227989
123establishment of protein localization to endoplasmic reticulum (GO:0072599)2.95280019
124mitotic nuclear envelope reassembly (GO:0007084)2.94296225
125nuclear envelope reassembly (GO:0031468)2.94296225
126cullin deneddylation (GO:0010388)2.91443922
127DNA replication initiation (GO:0006270)2.91275445
128mitochondrial DNA replication (GO:0006264)2.89557276
129spliceosomal snRNP assembly (GO:0000387)2.88214519
130protein deneddylation (GO:0000338)2.87947146
131deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.87889590
132exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.84735520
133negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.84713699
134negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.84194932
135ribosomal large subunit biogenesis (GO:0042273)2.82658045
136DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.79456292
137negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.77778278
138translation (GO:0006412)2.77518555
139mRNA cleavage (GO:0006379)2.75791516
140cellular protein complex disassembly (GO:0043624)2.74962997
141positive regulation of DNA repair (GO:0045739)2.73868687
142intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.73812999
143signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.73812999
144signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.73265401
145signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.73265401
146signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.73265401
147positive regulation of protein oligomerization (GO:0032461)2.72574048
148heme biosynthetic process (GO:0006783)2.70680959
149negative regulation of JAK-STAT cascade (GO:0046426)2.70371118
150positive regulation of developmental pigmentation (GO:0048087)2.70151725
151oxidative phosphorylation (GO:0006119)2.69206397
152protein neddylation (GO:0045116)2.69180185
153signal transduction involved in DNA integrity checkpoint (GO:0072401)2.67243758

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.59120793
2MYC_18555785_ChIP-Seq_MESCs_Mouse3.78061033
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.48632737
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.07147891
5MYC_18358816_ChIP-ChIP_MESCs_Mouse2.90718343
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.70879518
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.68213304
8ETS1_20019798_ChIP-Seq_JURKAT_Human2.64685869
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.60113566
10* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.57317458
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.49066240
12TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.42121810
13PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.34842827
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.31947961
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.18629594
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.17461371
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.14910946
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.14710692
19* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.10584599
20VDR_23849224_ChIP-Seq_CD4+_Human2.00795627
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.00045182
22DCP1A_22483619_ChIP-Seq_HELA_Human1.95839615
23SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.95301472
24SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.94869697
25FOXM1_23109430_ChIP-Seq_U2OS_Human1.91680903
26YY1_21170310_ChIP-Seq_MESCs_Mouse1.89775112
27NELFA_20434984_ChIP-Seq_ESCs_Mouse1.85629859
28GABP_19822575_ChIP-Seq_HepG2_Human1.85055905
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.85042878
30THAP11_20581084_ChIP-Seq_MESCs_Mouse1.84096347
31XRN2_22483619_ChIP-Seq_HELA_Human1.83281282
32* SRF_21415370_ChIP-Seq_HL-1_Mouse1.77894697
33VDR_21846776_ChIP-Seq_THP-1_Human1.76938919
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.71359363
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.63841137
36TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.63729225
37RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62985837
38TTF2_22483619_ChIP-Seq_HELA_Human1.62064478
39KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.59595016
40KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.59595016
41KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.59595016
42STAT3_1855785_ChIP-Seq_MESCs_Mouse1.56426745
43DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.54427194
44SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.53497117
45MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.53280809
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.52066803
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.52006277
48FOXP3_21729870_ChIP-Seq_TREG_Human1.51723940
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.51260007
50PU.1_20513432_ChIP-Seq_Bcells_Mouse1.50716646
51SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.48528719
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.47597183
53KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.47563682
54PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.44698043
55BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.43963599
56ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.43112480
57E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.37348716
58CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.36315746
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.35113143
60IRF8_22096565_ChIP-ChIP_GC-B_Human1.34112015
61* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.33135811
62E2F1_21310950_ChIP-Seq_MCF-7_Human1.27488809
63CTCF_18555785_ChIP-Seq_MESCs_Mouse1.27443832
64SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.27037046
65HOXB4_20404135_ChIP-ChIP_EML_Mouse1.26667417
66MYC_18940864_ChIP-ChIP_HL60_Human1.26444202
67POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.25600957
68E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25333546
69KDM5A_27292631_Chip-Seq_BREAST_Human1.24471420
70MYC_22102868_ChIP-Seq_BL_Human1.24007954
71ELK1_19687146_ChIP-ChIP_HELA_Human1.23440076
72SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.23235439
73ZNF263_19887448_ChIP-Seq_K562_Human1.23127173
74ZFX_18555785_ChIP-Seq_MESCs_Mouse1.22781600
75FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.21783916
76NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.20917321
77KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20871337
78AR_21909140_ChIP-Seq_LNCAP_Human1.20552308
79ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.20351729
80DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.19505059
81SPI1_23547873_ChIP-Seq_NB4_Human1.19345158
82MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.18579585
83ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.18528848
84NOTCH1_21737748_ChIP-Seq_TLL_Human1.18442094
85ERG_20887958_ChIP-Seq_HPC-7_Mouse1.15502742
86* FOXP1_21924763_ChIP-Seq_HESCs_Human1.15184797
87CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.14845874
88PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.14363292
89PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13766828
90NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.12789411
91SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.11085696
92MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.10572780
93ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10425338
94KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10033986
95ESR1_15608294_ChIP-ChIP_MCF-7_Human1.09638213
96NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.09632854
97GATA1_22383799_ChIP-Seq_G1ME_Mouse1.09270393
98TET1_21451524_ChIP-Seq_MESCs_Mouse1.08880936
99* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.08242925
100IRF8_21731497_ChIP-ChIP_J774_Mouse1.07686206
101TFEB_21752829_ChIP-Seq_HELA_Human1.07471114
102CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.07070494
103CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.05149511
104HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.05126006
105TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.04705644
106RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.04557819
107NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.03604981
108PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03422358
109NANOG_21062744_ChIP-ChIP_HESCs_Human1.03135456
110SOX2_18692474_ChIP-Seq_MEFs_Mouse1.01623660
111* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.01455455
112CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.98389629
113CIITA_25753668_ChIP-Seq_RAJI_Human0.98113008
114SRY_22984422_ChIP-ChIP_TESTIS_Rat0.97195033
115OCT4_18692474_ChIP-Seq_MEFs_Mouse0.96350287
116POU5F1_16518401_ChIP-PET_MESCs_Mouse0.95322162
117STAT1_20625510_ChIP-Seq_HELA_Human0.94382931
118TBX5_21415370_ChIP-Seq_HL-1_Mouse0.92244521
119ELK1_22589737_ChIP-Seq_MCF10A_Human0.90751424
120CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.89024345
121SOX2_18555785_ChIP-Seq_MESCs_Mouse0.88852511
122SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.87513137
123* CTCF_26484167_Chip-Seq_Bcells_Mouse0.84874781
124CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82327104
125CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.81987025
126SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.81272364
127HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.78139379
128GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77382443

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.52439229
2MP0003693_abnormal_embryo_hatching3.32929152
3MP0010094_abnormal_chromosome_stability3.21511616
4MP0009278_abnormal_bone_marrow3.15235924
5MP0009379_abnormal_foot_pigmentation3.08340167
6MP0004957_abnormal_blastocyst_morpholog2.86900612
7MP0008058_abnormal_DNA_repair2.66959133
8MP0001545_abnormal_hematopoietic_system2.58225525
9MP0005397_hematopoietic_system_phenotyp2.58225525
10MP0005171_absent_coat_pigmentation2.49760650
11MP0000372_irregular_coat_pigmentation2.46949531
12MP0003111_abnormal_nucleus_morphology2.44275195
13MP0002009_preneoplasia2.38630223
14MP0003077_abnormal_cell_cycle2.31826339
15MP0003786_premature_aging2.31548345
16MP0005174_abnormal_tail_pigmentation2.11880796
17MP0006035_abnormal_mitochondrial_morpho2.10638105
18MP0005075_abnormal_melanosome_morpholog2.07677440
19MP0000490_abnormal_crypts_of2.04518449
20MP0010030_abnormal_orbit_morphology2.01660426
21MP0002938_white_spotting1.98208480
22MP0008995_early_reproductive_senescence1.97390492
23MP0002234_abnormal_pharynx_morphology1.94033420
24MP0003123_paternal_imprinting1.89840070
25MP0002736_abnormal_nociception_after1.89658510
26MP0000685_abnormal_immune_system1.89503528
27MP0008932_abnormal_embryonic_tissue1.82809345
28MP0009333_abnormal_splenocyte_physiolog1.82718064
29MP0003718_maternal_effect1.76648739
30MP0002132_abnormal_respiratory_system1.74884220
31MP0002396_abnormal_hematopoietic_system1.74249064
32MP0005408_hypopigmentation1.73509331
33MP0003186_abnormal_redox_activity1.70320519
34MP0001529_abnormal_vocalization1.60239999
35MP0009697_abnormal_copulation1.52047736
36MP0002405_respiratory_system_inflammati1.51841696
37MP0000015_abnormal_ear_pigmentation1.50561372
38MP0003763_abnormal_thymus_physiology1.48470695
39MP0008007_abnormal_cellular_replicative1.47859413
40MP0001835_abnormal_antigen_presentation1.45518659
41MP0006082_CNS_inflammation1.44097640
42MP0003806_abnormal_nucleotide_metabolis1.43070410
43MP0002160_abnormal_reproductive_system1.42750147
44MP0002019_abnormal_tumor_incidence1.42428967
45MP0000049_abnormal_middle_ear1.42391826
46MP0005058_abnormal_lysosome_morphology1.38260655
47MP0000358_abnormal_cell_content/1.33969950
48MP0003656_abnormal_erythrocyte_physiolo1.33753039
49MP0008877_abnormal_DNA_methylation1.31726255
50MP0003315_abnormal_perineum_morphology1.31278245
51MP0000689_abnormal_spleen_morphology1.30682157
52MP0001853_heart_inflammation1.25620466
53MP0002148_abnormal_hypersensitivity_rea1.25231503
54MP0008875_abnormal_xenobiotic_pharmacok1.25027635
55MP0001727_abnormal_embryo_implantation1.24372096
56MP0002006_tumorigenesis1.22988959
57MP0003567_abnormal_fetal_cardiomyocyte1.22139907
58MP0002398_abnormal_bone_marrow1.21895080
59MP0009785_altered_susceptibility_to1.18148615
60MP0004133_heterotaxia1.18110332
61MP0001905_abnormal_dopamine_level1.17362352
62MP0000313_abnormal_cell_death1.16325683
63MP0000350_abnormal_cell_proliferation1.15632603
64MP0005670_abnormal_white_adipose1.14795560
65MP0002166_altered_tumor_susceptibility1.14391938
66MP0005025_abnormal_response_to1.14385759
67MP0002722_abnormal_immune_system1.13181060
68MP0008789_abnormal_olfactory_epithelium1.13005374
69MP0002210_abnormal_sex_determination1.11130251
70MP0001697_abnormal_embryo_size1.10801462
71MP0000371_diluted_coat_color1.09978969
72MP0002822_catalepsy1.09561132
73MP0000678_abnormal_parathyroid_gland1.09291685
74MP0005671_abnormal_response_to1.08110131
75MP0003436_decreased_susceptibility_to1.07086473
76MP0000470_abnormal_stomach_morphology1.06260290
77MP0001293_anophthalmia1.06009882
78MP0005389_reproductive_system_phenotype1.04982579
79MP0002653_abnormal_ependyma_morphology1.04929218
80MP0001968_abnormal_touch/_nociception1.02479307
81MP0002086_abnormal_extraembryonic_tissu1.02098110
82MP0001919_abnormal_reproductive_system1.01329498
83MP0003453_abnormal_keratinocyte_physiol1.01208441
84MP0010155_abnormal_intestine_physiology1.00703522
85MP0003890_abnormal_embryonic-extraembry0.99777118
86MP0002837_dystrophic_cardiac_calcinosis0.99037265
87MP0002429_abnormal_blood_cell0.98310657
88MP0005464_abnormal_platelet_physiology0.97775571
89MP0000716_abnormal_immune_system0.96252760
90MP0003136_yellow_coat_color0.95125135
91MP0001730_embryonic_growth_arrest0.94920257
92MP0004233_abnormal_muscle_weight0.94549310
93MP0005332_abnormal_amino_acid0.92895442
94MP0002277_abnormal_respiratory_mucosa0.92581600
95MP0002452_abnormal_antigen_presenting0.92425988
96MP0003937_abnormal_limbs/digits/tail_de0.91823947
97MP0002249_abnormal_larynx_morphology0.91781087
98MP0005501_abnormal_skin_physiology0.91309063
99MP0010352_gastrointestinal_tract_polyps0.90577486
100MP0002095_abnormal_skin_pigmentation0.90550051
101MP0006072_abnormal_retinal_apoptosis0.90543731
102MP0000566_synostosis0.90439634
103MP0000537_abnormal_urethra_morphology0.90092447
104MP0001800_abnormal_humoral_immune0.90085803
105MP0002163_abnormal_gland_morphology0.90011497
106MP0002723_abnormal_immune_serum0.89587993
107MP0002420_abnormal_adaptive_immunity0.89548912
108MP0001346_abnormal_lacrimal_gland0.89436426
109MP0001819_abnormal_immune_cell0.89060983
110MP0001672_abnormal_embryogenesis/_devel0.88767368
111MP0005380_embryogenesis_phenotype0.88767368
112MP0006036_abnormal_mitochondrial_physio0.88007598
113MP0003172_abnormal_lysosome_physiology0.87623477
114MP0001929_abnormal_gametogenesis0.87477979
115MP0003646_muscle_fatigue0.86655850
116MP0002282_abnormal_trachea_morphology0.86393643
117MP0000703_abnormal_thymus_morphology0.86362679
118MP0001881_abnormal_mammary_gland0.85872818
119MP0003724_increased_susceptibility_to0.85825753
120MP0005266_abnormal_metabolism0.85436232
121MP0004147_increased_porphyrin_level0.85350215
122MP0002085_abnormal_embryonic_tissue0.84034849
123MP0001764_abnormal_homeostasis0.83924208
124MP0005000_abnormal_immune_tolerance0.83825297
125MP0002080_prenatal_lethality0.82462075
126MP0001186_pigmentation_phenotype0.81998165
127MP0000653_abnormal_sex_gland0.81693566
128MP0002419_abnormal_innate_immunity0.81162806
129MP0003828_pulmonary_edema0.81046563
130MP0001119_abnormal_female_reproductive0.80686725
131MP0010307_abnormal_tumor_latency0.79864176
132MP0003121_genomic_imprinting0.77588940
133MP0002102_abnormal_ear_morphology0.77472091
134MP0002697_abnormal_eye_size0.77321776
135MP0005499_abnormal_olfactory_system0.76266049
136MP0005394_taste/olfaction_phenotype0.76266049
137MP0002075_abnormal_coat/hair_pigmentati0.75667232
138MP0001661_extended_life_span0.74558254
139MP0005377_hearing/vestibular/ear_phenot0.73603419
140MP0003878_abnormal_ear_physiology0.73603419
141MP0002111_abnormal_tail_morphology0.73566506
142MP0002084_abnormal_developmental_patter0.72582126
143MP0001145_abnormal_male_reproductive0.72027923
144MP0003941_abnormal_skin_development0.72027428
145MP0006292_abnormal_olfactory_placode0.70344047
146MP0008872_abnormal_physiological_respon0.70153631
147MP0003011_delayed_dark_adaptation0.70117829
148MP0004197_abnormal_fetal_growth/weight/0.68854571
149MP0001873_stomach_inflammation0.68025788
150MP0003938_abnormal_ear_development0.66753485
151MP0001845_abnormal_inflammatory_respons0.66607468
152MP0003137_abnormal_impulse_conducting0.64817287
153MP0009672_abnormal_birth_weight0.64761188
154MP0005646_abnormal_pituitary_gland0.64608061
155MP0002177_abnormal_outer_ear0.64243908
156MP0003698_abnormal_male_reproductive0.61989500
157MP0005330_cardiomyopathy0.61732040

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.96645275
2Abnormal mitochondria in muscle tissue (HP:0008316)5.94913327
3Acute encephalopathy (HP:0006846)5.39841169
4Mitochondrial inheritance (HP:0001427)5.38488691
5Increased CSF lactate (HP:0002490)4.90754445
6Progressive macrocephaly (HP:0004481)4.80708324
7Hepatocellular necrosis (HP:0001404)4.78612488
8Increased IgM level (HP:0003496)4.61394804
9Pustule (HP:0200039)4.51963832
10Increased hepatocellular lipid droplets (HP:0006565)4.33220331
11Hepatic necrosis (HP:0002605)4.32914934
12Lipid accumulation in hepatocytes (HP:0006561)4.05828832
13Renal Fanconi syndrome (HP:0001994)4.05741333
14Cerebral edema (HP:0002181)4.03530995
15Increased intramyocellular lipid droplets (HP:0012240)4.01297448
16Poikiloderma (HP:0001029)3.86599572
17Concave nail (HP:0001598)3.79485998
18Abnormal number of erythroid precursors (HP:0012131)3.74222769
19Abnormality of cells of the erythroid lineage (HP:0012130)3.73648427
20Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.62228979
21Rectal fistula (HP:0100590)3.61072253
22Rectovaginal fistula (HP:0000143)3.61072253
23Rib fusion (HP:0000902)3.59322293
24Lactic acidosis (HP:0003128)3.49808511
25Increased muscle lipid content (HP:0009058)3.49446004
26Increased serum lactate (HP:0002151)3.45398738
27Exertional dyspnea (HP:0002875)3.42965002
28Tongue fasciculations (HP:0001308)3.39322966
29Reticulocytopenia (HP:0001896)3.32262013
30Exercise intolerance (HP:0003546)3.29322199
31Abnormal hemoglobin (HP:0011902)3.24761770
32Premature graying of hair (HP:0002216)3.23639878
33Vaginal fistula (HP:0004320)3.22940177
34Respiratory failure (HP:0002878)3.19516458
35Absent thumb (HP:0009777)3.15682566
36Microvesicular hepatic steatosis (HP:0001414)3.13813549
37Abnormality of male internal genitalia (HP:0000022)3.07748601
38Intestinal fistula (HP:0100819)3.07547359
39Facial hemangioma (HP:0000329)3.02083111
40Muscle fiber atrophy (HP:0100295)2.93568848
41Patellar aplasia (HP:0006443)2.92538739
42Muscle fibrillation (HP:0010546)2.91387838
43Absent radius (HP:0003974)2.89347684
44Respiratory difficulties (HP:0002880)2.79327329
45Type 2 muscle fiber atrophy (HP:0003554)2.76891019
46Alopecia of scalp (HP:0002293)2.76543553
47Albinism (HP:0001022)2.76002603
48Aplasia/Hypoplasia of the sacrum (HP:0008517)2.75172263
49Leukodystrophy (HP:0002415)2.73662184
50Intestinal atresia (HP:0011100)2.72535867
51Aplasia/Hypoplasia of the patella (HP:0006498)2.70838020
52Increased serum pyruvate (HP:0003542)2.70143996
53Abnormality of glycolysis (HP:0004366)2.67444143
54Aplasia involving forearm bones (HP:0009822)2.66332196
55Absent forearm bone (HP:0003953)2.66332196
56Colon cancer (HP:0003003)2.61568776
57Lethargy (HP:0001254)2.59783459
58Testicular atrophy (HP:0000029)2.58790618
59Annular pancreas (HP:0001734)2.58432471
60Squamous cell carcinoma (HP:0002860)2.56429675
61Breast hypoplasia (HP:0003187)2.56293215
623-Methylglutaconic aciduria (HP:0003535)2.55224245
63Chromosomal breakage induced by crosslinking agents (HP:0003221)2.51635154
64Aplasia/hypoplasia of the humerus (HP:0006507)2.48470394
65Abnormal protein glycosylation (HP:0012346)2.48265408
66Abnormal glycosylation (HP:0012345)2.48265408
67Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.48265408
68Abnormal protein N-linked glycosylation (HP:0012347)2.48265408
69Birth length less than 3rd percentile (HP:0003561)2.47626728
70Hypochromic microcytic anemia (HP:0004840)2.45983053
71Hypochromic anemia (HP:0001931)2.45703457
72Optic disc pallor (HP:0000543)2.44670346
73Rough bone trabeculation (HP:0100670)2.44054046
74Microretrognathia (HP:0000308)2.43536634
75IgA deficiency (HP:0002720)2.38658149
76Selective tooth agenesis (HP:0001592)2.37454989
77Male infertility (HP:0003251)2.36455839
78Chromsome breakage (HP:0040012)2.30630271
79Redundant skin (HP:0001582)2.30536124
80IgG deficiency (HP:0004315)2.28379154
81Hypoplasia of the radius (HP:0002984)2.27338567
82Abnormality of placental membranes (HP:0011409)2.25916355
83Amniotic constriction ring (HP:0009775)2.25916355
84Pancytopenia (HP:0001876)2.25838799
85Orthostatic hypotension (HP:0001278)2.25284560
86Type I transferrin isoform profile (HP:0003642)2.24142466
87Methylmalonic aciduria (HP:0012120)2.22410737
88Pallor (HP:0000980)2.20852036
89Abnormality of renal resorption (HP:0011038)2.20534640
90Abnormality of the preputium (HP:0100587)2.19771164
91Macrocytic anemia (HP:0001972)2.19552498
92Abnormality of the ileum (HP:0001549)2.19307318
93Abnormality of T cell physiology (HP:0011840)2.18225933
94Hypokinesia (HP:0002375)2.18022848
95Meckel diverticulum (HP:0002245)2.16825950
96Aplastic anemia (HP:0001915)2.15080405
97Decreased activity of mitochondrial respiratory chain (HP:0008972)2.14527358
98Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.14527358
99Oral leukoplakia (HP:0002745)2.13766919
100Short humerus (HP:0005792)2.13581814
101Emotional lability (HP:0000712)2.13291481
102CNS demyelination (HP:0007305)2.13180631
103Recurrent abscess formation (HP:0002722)2.12697285
104Degeneration of anterior horn cells (HP:0002398)2.12568676
105Abnormality of the anterior horn cell (HP:0006802)2.12568676
106Acute lymphatic leukemia (HP:0006721)2.11716394
107Hyperglycinemia (HP:0002154)2.10786020
108Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.10388313
109Vertebral hypoplasia (HP:0008417)2.10388313
110IgM deficiency (HP:0002850)2.09303736
111Diaphragmatic weakness (HP:0009113)2.09290173
112Aplasia of the musculature (HP:0100854)2.07076594
113Premature skin wrinkling (HP:0100678)2.05466433
114Aplasia/Hypoplasia of the uvula (HP:0010293)2.05225993
115Pulmonary fibrosis (HP:0002206)2.03668150
116Ragged-red muscle fibers (HP:0003200)2.00006527
117Basal cell carcinoma (HP:0002671)1.99748257
118Sclerocornea (HP:0000647)1.99407222
119Hyperthyroidism (HP:0000836)1.99385097
120Aplasia/Hypoplasia involving the musculature (HP:0001460)1.98785574
121Petechiae (HP:0000967)1.98740294
122Progressive muscle weakness (HP:0003323)1.98555256
123Dicarboxylic aciduria (HP:0003215)1.98097876
124Abnormality of dicarboxylic acid metabolism (HP:0010995)1.98097876
125Cleft eyelid (HP:0000625)1.97588889
126Joint stiffness (HP:0001387)1.96674776
127Mucopolysacchariduria (HP:0008155)1.96478055
128Urinary glycosaminoglycan excretion (HP:0003541)1.96478055
129X-linked dominant inheritance (HP:0001423)1.95863296
130Reduced antithrombin III activity (HP:0001976)1.95723105
131Spinal muscular atrophy (HP:0007269)1.95103178
132Capillary hemangiomas (HP:0005306)1.94679669
133Abnormality of methionine metabolism (HP:0010901)1.94419111
134Generalized aminoaciduria (HP:0002909)1.93240498
135Opisthotonus (HP:0002179)1.92171545
136Large for gestational age (HP:0001520)1.91407724
137Abnormality of aromatic amino acid family metabolism (HP:0004338)1.91236856
138Lymphoma (HP:0002665)1.90734433
139Multiple enchondromatosis (HP:0005701)1.90623137
140Dysautonomia (HP:0002459)1.90558143
141Abnormal number of incisors (HP:0011064)1.90176318
142Cheilitis (HP:0100825)1.88612284
143Sparse eyelashes (HP:0000653)1.86590049
144Hypotrichosis (HP:0001006)1.85951852
145Myelodysplasia (HP:0002863)1.85847169
146Ulnar bowing (HP:0003031)1.85760322
147Carpal bone hypoplasia (HP:0001498)1.84601656
148Cerebral hypomyelination (HP:0006808)1.83940480
149Abnormal trabecular bone morphology (HP:0100671)1.83460704
150Cutaneous melanoma (HP:0012056)1.82452285
151Anorexia (HP:0002039)1.80506595
152Progressive microcephaly (HP:0000253)1.80185238
153Bifid uvula (HP:0000193)1.80037595
154Dysostosis multiplex (HP:0000943)1.79715155
155Glycosuria (HP:0003076)1.78217457
156Abnormality of urine glucose concentration (HP:0011016)1.78217457
157Popliteal pterygium (HP:0009756)1.76696097
158Hyperphosphaturia (HP:0003109)1.75251696
159Short chin (HP:0000331)1.74933813
160Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.74825550
161Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.73538830
162Blindness (HP:0000618)1.73250754
163Abnormality of glycosaminoglycan metabolism (HP:0004371)1.72899226
164Abnormality of mucopolysaccharide metabolism (HP:0011020)1.72899226
165Facial cleft (HP:0002006)1.70447332
166Truncus arteriosus (HP:0001660)1.67522227
167Congenital ichthyosiform erythroderma (HP:0007431)1.67323749
168Abnormality of serum amino acid levels (HP:0003112)1.66031606
169Methylmalonic acidemia (HP:0002912)1.64208918
170Megaloblastic anemia (HP:0001889)1.62364431
171Horseshoe kidney (HP:0000085)1.62122829
172Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.59198125
173Triphalangeal thumb (HP:0001199)1.58870384

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK26.33919577
2MAPK153.88452445
3PIM23.66640103
4ICK3.50563035
5MAP3K63.40662713
6MAP3K113.19254298
7PINK12.88790339
8DDR22.83538950
9BUB12.78033310
10NME22.71982528
11NME12.48051630
12MATK2.46794979
13WEE12.35443554
14TAF12.17322039
15CDK72.09000436
16YES12.08584435
17DAPK12.01075946
18SMG11.92969064
19PIM11.89237519
20NUAK11.78428869
21STK161.77664084
22CSK1.70244140
23FGR1.67005628
24NEK11.65162505
25VRK11.51368310
26PLK31.51332278
27DYRK31.48739806
28TESK11.44113437
29UHMK11.40864742
30DYRK1B1.38837338
31PLK11.37928879
32IRAK41.35659432
33TRPM71.33731779
34MAP3K121.31437318
35CSNK1G31.31370017
36PLK41.28167648
37BMX1.24608668
38MAP4K11.24332083
39LIMK11.24197954
40TLK11.23932067
41EIF2AK11.23354350
42CHEK21.22117089
43PRKD21.17035382
44RPS6KL11.15441453
45RPS6KC11.15441453
46KDR1.12459378
47AKT31.12239463
48IRAK31.11187808
49CCNB11.08950278
50RPS6KA61.07252121
51ILK1.05752424
52CDC71.05093447
53IKBKB1.04948111
54ATR1.03005833
55BLK1.01462042
56CDK81.00495009
57TYRO30.99600317
58CSNK1A1L0.99298338
59CDK60.98191340
60RPS6KB20.97737168
61SRPK10.97668003
62CSNK1G10.97001087
63BRSK20.96808217
64PDK20.95920024
65ACVR1B0.93133217
66AURKB0.92834951
67NEK20.92178503
68CSNK1G20.91484736
69EIF2AK30.90635738
70LYN0.88775157
71MAPK110.88234918
72TSSK60.86263583
73TESK20.84419977
74CSNK2A10.84178191
75TAOK20.83755863
76DYRK20.83589480
77TRIM280.82653799
78AURKA0.80851468
79ARAF0.80812403
80MAP3K100.79546657
81PAK40.78905373
82LRRK20.78353454
83EPHA20.77808541
84PRKCI0.77533910
85DAPK30.76790620
86MAP2K70.75420070
87MST40.74365415
88SCYL20.72295416
89TXK0.72098143
90BCKDK0.69128096
91RPS6KA50.68776604
92MAPKAPK50.67510944
93PRKD30.67254357
94TTK0.64242459
95MST1R0.63814280
96ZAK0.60552721
97ERBB30.57436000
98PBK0.57415578
99MAPKAPK30.57040765
100RAF10.56541216
101GSK3A0.56131318
102CSNK2A20.56101938
103RPS6KA10.55995827
104STK40.55774963
105ABL20.55290153
106MAP4K20.54543802
107PAK10.54055605
108GRK50.53200103
109TYK20.51394863
110BTK0.51362275
111BRSK10.48839520
112MAPK40.48431805
113TEC0.46538161
114CDK40.46299962
115ZAP700.46254620
116CDK20.45562438
117TBK10.44817160
118MAPKAPK20.43235432
119BRAF0.42688437
120STK100.42493111
121LCK0.42075406
122CHUK0.40906971
123PRKCD0.40188895
124CHEK10.39258292
125MUSK0.38621470
126ATM0.38165604
127WNK30.37100353
128KIT0.37054649
129EIF2AK20.36991527
130RPS6KA40.36442744
131AKT20.36195776
132MAPK30.35842439
133HIPK20.35806028
134TIE10.35414107
135MAP3K80.33300204
136CAMK2G0.32992007
137CDC42BPA0.31818256
138PDGFRA0.31812445
139CDK10.30419643
140CDK11A0.30124790
141CDK180.29692762
142CDK150.29162792
143CDK140.28511996
144BMPR1B0.28246959
145EPHB20.26982410
146CSNK1A10.26305340
147CDK90.24833845
148CSNK1E0.24287042
149IRAK20.21319659
150MINK10.18007071
151CAMK2D0.17820444

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.67381201
2Mismatch repair_Homo sapiens_hsa034304.58828556
3Base excision repair_Homo sapiens_hsa034104.15172785
4Ribosome_Homo sapiens_hsa030103.93736024
5Proteasome_Homo sapiens_hsa030503.29240267
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.82852776
7Homologous recombination_Homo sapiens_hsa034402.75661261
8Nucleotide excision repair_Homo sapiens_hsa034202.72574119
9RNA polymerase_Homo sapiens_hsa030202.71719064
10Spliceosome_Homo sapiens_hsa030402.59307344
11Pyrimidine metabolism_Homo sapiens_hsa002402.08468404
12RNA transport_Homo sapiens_hsa030132.05952996
13Fatty acid biosynthesis_Homo sapiens_hsa000611.82391170
14Folate biosynthesis_Homo sapiens_hsa007901.78544215
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.66389000
16Cell cycle_Homo sapiens_hsa041101.62786403
17Sulfur relay system_Homo sapiens_hsa041221.59598450
18* Fanconi anemia pathway_Homo sapiens_hsa034601.59586740
19Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.58506768
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.54169899
21p53 signaling pathway_Homo sapiens_hsa041151.50663345
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.47833996
23Sulfur metabolism_Homo sapiens_hsa009201.34545444
24Basal transcription factors_Homo sapiens_hsa030221.34231132
25One carbon pool by folate_Homo sapiens_hsa006701.32197073
26Primary immunodeficiency_Homo sapiens_hsa053401.30287409
27RNA degradation_Homo sapiens_hsa030181.29066239
28Pyruvate metabolism_Homo sapiens_hsa006201.20637402
29Cardiac muscle contraction_Homo sapiens_hsa042601.20384956
30Oxidative phosphorylation_Homo sapiens_hsa001901.20300104
31Parkinsons disease_Homo sapiens_hsa050121.14765071
32Arginine and proline metabolism_Homo sapiens_hsa003301.12315957
33Protein export_Homo sapiens_hsa030601.07653590
34mRNA surveillance pathway_Homo sapiens_hsa030151.06577026
35Non-homologous end-joining_Homo sapiens_hsa034501.03703797
36Carbon metabolism_Homo sapiens_hsa012001.03145096
37Legionellosis_Homo sapiens_hsa051341.02619005
38Huntingtons disease_Homo sapiens_hsa050161.01047937
39Glutathione metabolism_Homo sapiens_hsa004800.99265152
40Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.97455541
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.97302517
42Vitamin B6 metabolism_Homo sapiens_hsa007500.96121448
43Pentose and glucuronate interconversions_Homo sapiens_hsa000400.92683308
44Herpes simplex infection_Homo sapiens_hsa051680.91298873
45Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.90526882
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.89410718
47Purine metabolism_Homo sapiens_hsa002300.84388348
48Notch signaling pathway_Homo sapiens_hsa043300.83952824
49Epstein-Barr virus infection_Homo sapiens_hsa051690.82805787
50Biosynthesis of amino acids_Homo sapiens_hsa012300.82345302
51Shigellosis_Homo sapiens_hsa051310.80436061
52Graft-versus-host disease_Homo sapiens_hsa053320.79530266
53Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76609646
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75565007
55Fructose and mannose metabolism_Homo sapiens_hsa000510.73119566
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.72598743
57Transcriptional misregulation in cancer_Homo sapiens_hsa052020.72255238
58Peroxisome_Homo sapiens_hsa041460.69405867
59Propanoate metabolism_Homo sapiens_hsa006400.69354931
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.67988905
61Allograft rejection_Homo sapiens_hsa053300.67505003
62Intestinal immune network for IgA production_Homo sapiens_hsa046720.65223524
63Drug metabolism - other enzymes_Homo sapiens_hsa009830.63724017
64Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.63575953
65Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.63340792
662-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.63307669
67Measles_Homo sapiens_hsa051620.63244826
68Tyrosine metabolism_Homo sapiens_hsa003500.62047982
69Circadian rhythm_Homo sapiens_hsa047100.60986961
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.59140504
71Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.54177822
72Cysteine and methionine metabolism_Homo sapiens_hsa002700.52774302
73Pentose phosphate pathway_Homo sapiens_hsa000300.50684188
74Arachidonic acid metabolism_Homo sapiens_hsa005900.50634246
75Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.49600781
76Antigen processing and presentation_Homo sapiens_hsa046120.49138699
77RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.49055562
78Galactose metabolism_Homo sapiens_hsa000520.47587691
79Phenylalanine metabolism_Homo sapiens_hsa003600.47463537
80Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45815143
81Glycosaminoglycan degradation_Homo sapiens_hsa005310.44948734
82Metabolic pathways_Homo sapiens_hsa011000.44518943
83Maturity onset diabetes of the young_Homo sapiens_hsa049500.44452519
84Alzheimers disease_Homo sapiens_hsa050100.43884989
85Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.43387654
86Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.41250845
87Collecting duct acid secretion_Homo sapiens_hsa049660.41246836
88Other glycan degradation_Homo sapiens_hsa005110.39477572
89Viral carcinogenesis_Homo sapiens_hsa052030.38682220
90Hematopoietic cell lineage_Homo sapiens_hsa046400.38205853
91TGF-beta signaling pathway_Homo sapiens_hsa043500.38053483
92NF-kappa B signaling pathway_Homo sapiens_hsa040640.38017312
93Asthma_Homo sapiens_hsa053100.37686228
94Leishmaniasis_Homo sapiens_hsa051400.34642654
95Vibrio cholerae infection_Homo sapiens_hsa051100.33267770
96Apoptosis_Homo sapiens_hsa042100.32560967
97Fatty acid elongation_Homo sapiens_hsa000620.32196373
98Hedgehog signaling pathway_Homo sapiens_hsa043400.31946293
99Systemic lupus erythematosus_Homo sapiens_hsa053220.31727254
100Cyanoamino acid metabolism_Homo sapiens_hsa004600.31570997
101Hippo signaling pathway_Homo sapiens_hsa043900.31432274
102Fatty acid metabolism_Homo sapiens_hsa012120.30610953
103Basal cell carcinoma_Homo sapiens_hsa052170.30393787
104Chemical carcinogenesis_Homo sapiens_hsa052040.28255871
105N-Glycan biosynthesis_Homo sapiens_hsa005100.28040801
106Butanoate metabolism_Homo sapiens_hsa006500.27923757
107Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.27282192
108Lysosome_Homo sapiens_hsa041420.27191294
109Steroid biosynthesis_Homo sapiens_hsa001000.26558424
110Fatty acid degradation_Homo sapiens_hsa000710.26378345
111Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.26332761
112Vitamin digestion and absorption_Homo sapiens_hsa049770.26237518
113HTLV-I infection_Homo sapiens_hsa051660.24466910
114Viral myocarditis_Homo sapiens_hsa054160.23779752
115Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.23643779
116Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.22587140
117Bladder cancer_Homo sapiens_hsa052190.21573679
118Selenocompound metabolism_Homo sapiens_hsa004500.21504409
119Hepatitis B_Homo sapiens_hsa051610.21389545
120Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.20327997
121Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.20165037
122beta-Alanine metabolism_Homo sapiens_hsa004100.19760808
123Staphylococcus aureus infection_Homo sapiens_hsa051500.19699593
124Primary bile acid biosynthesis_Homo sapiens_hsa001200.19040382
125Acute myeloid leukemia_Homo sapiens_hsa052210.18921552
126Linoleic acid metabolism_Homo sapiens_hsa005910.18446876
127Adherens junction_Homo sapiens_hsa045200.18047232
128Oocyte meiosis_Homo sapiens_hsa041140.17829533
129mTOR signaling pathway_Homo sapiens_hsa041500.17533592
130Alcoholism_Homo sapiens_hsa050340.17114967
131Tryptophan metabolism_Homo sapiens_hsa003800.16559229
132Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.12401736
133Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.12353838
134Caffeine metabolism_Homo sapiens_hsa002320.12311958
135Arginine biosynthesis_Homo sapiens_hsa002200.11371573
136SNARE interactions in vesicular transport_Homo sapiens_hsa041300.09548535
137Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.09411679
138Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.05181635
139Fat digestion and absorption_Homo sapiens_hsa049750.04471232

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