

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.86136443 |
| 2 | proline biosynthetic process (GO:0006561) | 6.94321815 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.11315598 |
| 4 | transcription from mitochondrial promoter (GO:0006390) | 6.08951299 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 5.49783432 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.49783432 |
| 7 | proline metabolic process (GO:0006560) | 5.49214433 |
| 8 | telomere maintenance via semi-conservative replication (GO:0032201) | 5.16181641 |
| 9 | regulation of mitochondrial translation (GO:0070129) | 4.99016715 |
| 10 | chaperone-mediated protein transport (GO:0072321) | 4.91053791 |
| 11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.72984117 |
| 12 | formation of translation preinitiation complex (GO:0001731) | 4.65292141 |
| 13 | viral mRNA export from host cell nucleus (GO:0046784) | 4.63842712 |
| 14 | protein complex biogenesis (GO:0070271) | 4.62282635 |
| 15 | respiratory electron transport chain (GO:0022904) | 4.60599999 |
| 16 | positive regulation of protein homooligomerization (GO:0032464) | 4.57507291 |
| 17 | electron transport chain (GO:0022900) | 4.50767750 |
| 18 | telomere maintenance via recombination (GO:0000722) | 4.46849320 |
| 19 | * replication fork processing (GO:0031297) | 4.44957163 |
| 20 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.41802844 |
| 21 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.39535570 |
| 22 | embryonic process involved in female pregnancy (GO:0060136) | 4.39465639 |
| 23 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 4.26239499 |
| 24 | DNA strand elongation (GO:0022616) | 4.16414570 |
| 25 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.15091822 |
| 26 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.15091822 |
| 27 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.13377798 |
| 28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.13377798 |
| 29 | NADH dehydrogenase complex assembly (GO:0010257) | 4.13377798 |
| 30 | * maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 4.06550173 |
| 31 | negative regulation of ligase activity (GO:0051352) | 4.02727945 |
| 32 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.02727945 |
| 33 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.02008918 |
| 34 | protein targeting to mitochondrion (GO:0006626) | 3.99328201 |
| 35 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.98360648 |
| 36 | ribosomal small subunit assembly (GO:0000028) | 3.97176971 |
| 37 | proteasome assembly (GO:0043248) | 3.95660777 |
| 38 | oxidative demethylation (GO:0070989) | 3.90603868 |
| 39 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.89722286 |
| 40 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.89187262 |
| 41 | viral transcription (GO:0019083) | 3.84620004 |
| 42 | mitochondrial DNA metabolic process (GO:0032042) | 3.83030463 |
| 43 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.81970180 |
| 44 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.81113469 |
| 45 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.80823118 |
| 46 | termination of RNA polymerase III transcription (GO:0006386) | 3.80823118 |
| 47 | mitotic recombination (GO:0006312) | 3.76895851 |
| 48 | establishment of protein localization to mitochondrion (GO:0072655) | 3.74522184 |
| 49 | GDP-mannose metabolic process (GO:0019673) | 3.73309154 |
| 50 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.71217779 |
| 51 | rRNA modification (GO:0000154) | 3.68262523 |
| 52 | translational termination (GO:0006415) | 3.66745040 |
| 53 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.65259760 |
| 54 | GTP biosynthetic process (GO:0006183) | 3.65193357 |
| 55 | telomere maintenance via telomere lengthening (GO:0010833) | 3.64169931 |
| 56 | DNA replication checkpoint (GO:0000076) | 3.62001358 |
| 57 | regulation of integrin activation (GO:0033623) | 3.61780481 |
| 58 | base-excision repair (GO:0006284) | 3.61194618 |
| 59 | poly(A)+ mRNA export from nucleus (GO:0016973) | 3.60061893 |
| 60 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.59411986 |
| 61 | protein localization to mitochondrion (GO:0070585) | 3.58344244 |
| 62 | establishment of integrated proviral latency (GO:0075713) | 3.57502039 |
| 63 | DNA integration (GO:0015074) | 3.56919358 |
| 64 | cytochrome complex assembly (GO:0017004) | 3.56744220 |
| 65 | maturation of 5.8S rRNA (GO:0000460) | 3.54731752 |
| 66 | base-excision repair, AP site formation (GO:0006285) | 3.54521153 |
| 67 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.53776078 |
| 68 | ribosomal small subunit biogenesis (GO:0042274) | 3.53092265 |
| 69 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.51836219 |
| 70 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.51427121 |
| 71 | regulation of protein homooligomerization (GO:0032462) | 3.51162441 |
| 72 | mitochondrial RNA metabolic process (GO:0000959) | 3.49960906 |
| 73 | DNA strand renaturation (GO:0000733) | 3.48117716 |
| 74 | respiratory chain complex IV assembly (GO:0008535) | 3.46495753 |
| 75 | cellular component biogenesis (GO:0044085) | 3.45862765 |
| 76 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.45542410 |
| 77 | CTP metabolic process (GO:0046036) | 3.44863370 |
| 78 | CTP biosynthetic process (GO:0006241) | 3.44863370 |
| 79 | UTP biosynthetic process (GO:0006228) | 3.44566485 |
| 80 | chromatin remodeling at centromere (GO:0031055) | 3.43598905 |
| 81 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.41663119 |
| 82 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.41292618 |
| 83 | translational initiation (GO:0006413) | 3.39004720 |
| 84 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.38828239 |
| 85 | cellular response to zinc ion (GO:0071294) | 3.38701645 |
| 86 | positive regulation of ligase activity (GO:0051351) | 3.36978053 |
| 87 | translational elongation (GO:0006414) | 3.35939448 |
| 88 | meiotic chromosome segregation (GO:0045132) | 3.35524707 |
| 89 | CENP-A containing nucleosome assembly (GO:0034080) | 3.35299691 |
| 90 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.32543787 |
| 91 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.31095628 |
| 92 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.30693089 |
| 93 | ATP biosynthetic process (GO:0006754) | 3.30502412 |
| 94 | termination of RNA polymerase II transcription (GO:0006369) | 3.28972024 |
| 95 | peptidyl-histidine modification (GO:0018202) | 3.28483694 |
| 96 | inner mitochondrial membrane organization (GO:0007007) | 3.27465126 |
| 97 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.27102856 |
| 98 | maturation of SSU-rRNA (GO:0030490) | 3.24201509 |
| 99 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.23978938 |
| 100 | pseudouridine synthesis (GO:0001522) | 3.22425724 |
| 101 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.18852590 |
| 102 | DNA ligation (GO:0006266) | 3.18707238 |
| 103 | DNA double-strand break processing (GO:0000729) | 3.18631120 |
| 104 | cotranslational protein targeting to membrane (GO:0006613) | 3.18056540 |
| 105 | rRNA processing (GO:0006364) | 3.17386502 |
| 106 | ribosome biogenesis (GO:0042254) | 3.17138088 |
| 107 | protein targeting to ER (GO:0045047) | 3.17028144 |
| 108 | protein maturation by protein folding (GO:0022417) | 3.16865005 |
| 109 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.15468962 |
| 110 | establishment of apical/basal cell polarity (GO:0035089) | 3.14699428 |
| 111 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.13145790 |
| 112 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.11990832 |
| 113 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.10339495 |
| 114 | non-recombinational repair (GO:0000726) | 3.03606477 |
| 115 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.03606477 |
| 116 | rRNA metabolic process (GO:0016072) | 3.03532982 |
| 117 | protein localization to endoplasmic reticulum (GO:0070972) | 3.01178532 |
| 118 | G1 DNA damage checkpoint (GO:0044783) | 2.99954584 |
| 119 | mitotic G1/S transition checkpoint (GO:0044819) | 2.99187495 |
| 120 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.97282603 |
| 121 | negative regulation of cell cycle arrest (GO:0071157) | 2.96882119 |
| 122 | viral life cycle (GO:0019058) | 2.96227989 |
| 123 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.95280019 |
| 124 | mitotic nuclear envelope reassembly (GO:0007084) | 2.94296225 |
| 125 | nuclear envelope reassembly (GO:0031468) | 2.94296225 |
| 126 | cullin deneddylation (GO:0010388) | 2.91443922 |
| 127 | DNA replication initiation (GO:0006270) | 2.91275445 |
| 128 | mitochondrial DNA replication (GO:0006264) | 2.89557276 |
| 129 | spliceosomal snRNP assembly (GO:0000387) | 2.88214519 |
| 130 | protein deneddylation (GO:0000338) | 2.87947146 |
| 131 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.87889590 |
| 132 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.84735520 |
| 133 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.84713699 |
| 134 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.84194932 |
| 135 | ribosomal large subunit biogenesis (GO:0042273) | 2.82658045 |
| 136 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.79456292 |
| 137 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.77778278 |
| 138 | translation (GO:0006412) | 2.77518555 |
| 139 | mRNA cleavage (GO:0006379) | 2.75791516 |
| 140 | cellular protein complex disassembly (GO:0043624) | 2.74962997 |
| 141 | positive regulation of DNA repair (GO:0045739) | 2.73868687 |
| 142 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.73812999 |
| 143 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.73812999 |
| 144 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.73265401 |
| 145 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.73265401 |
| 146 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.73265401 |
| 147 | positive regulation of protein oligomerization (GO:0032461) | 2.72574048 |
| 148 | heme biosynthetic process (GO:0006783) | 2.70680959 |
| 149 | negative regulation of JAK-STAT cascade (GO:0046426) | 2.70371118 |
| 150 | positive regulation of developmental pigmentation (GO:0048087) | 2.70151725 |
| 151 | oxidative phosphorylation (GO:0006119) | 2.69206397 |
| 152 | protein neddylation (GO:0045116) | 2.69180185 |
| 153 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.67243758 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.59120793 |
| 2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.78061033 |
| 3 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.48632737 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.07147891 |
| 5 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.90718343 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.70879518 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.68213304 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.64685869 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.60113566 |
| 10 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.57317458 |
| 11 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.49066240 |
| 12 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.42121810 |
| 13 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.34842827 |
| 14 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.31947961 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.18629594 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.17461371 |
| 17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.14910946 |
| 18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.14710692 |
| 19 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.10584599 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.00795627 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.00045182 |
| 22 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.95839615 |
| 23 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.95301472 |
| 24 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.94869697 |
| 25 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.91680903 |
| 26 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.89775112 |
| 27 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.85629859 |
| 28 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.85055905 |
| 29 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.85042878 |
| 30 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.84096347 |
| 31 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.83281282 |
| 32 | * SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.77894697 |
| 33 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.76938919 |
| 34 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.71359363 |
| 35 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.63841137 |
| 36 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63729225 |
| 37 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.62985837 |
| 38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.62064478 |
| 39 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.59595016 |
| 40 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.59595016 |
| 41 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.59595016 |
| 42 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.56426745 |
| 43 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.54427194 |
| 44 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.53497117 |
| 45 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.53280809 |
| 46 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.52066803 |
| 47 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.52006277 |
| 48 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.51723940 |
| 49 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.51260007 |
| 50 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.50716646 |
| 51 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.48528719 |
| 52 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47597183 |
| 53 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.47563682 |
| 54 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.44698043 |
| 55 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.43963599 |
| 56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.43112480 |
| 57 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.37348716 |
| 58 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.36315746 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.35113143 |
| 60 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.34112015 |
| 61 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.33135811 |
| 62 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.27488809 |
| 63 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.27443832 |
| 64 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.27037046 |
| 65 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.26667417 |
| 66 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.26444202 |
| 67 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.25600957 |
| 68 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.25333546 |
| 69 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.24471420 |
| 70 | MYC_22102868_ChIP-Seq_BL_Human | 1.24007954 |
| 71 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.23440076 |
| 72 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23235439 |
| 73 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.23127173 |
| 74 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.22781600 |
| 75 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.21783916 |
| 76 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.20917321 |
| 77 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.20871337 |
| 78 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.20552308 |
| 79 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.20351729 |
| 80 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.19505059 |
| 81 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.19345158 |
| 82 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.18579585 |
| 83 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.18528848 |
| 84 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.18442094 |
| 85 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.15502742 |
| 86 | * FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.15184797 |
| 87 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.14845874 |
| 88 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14363292 |
| 89 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.13766828 |
| 90 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12789411 |
| 91 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.11085696 |
| 92 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.10572780 |
| 93 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.10425338 |
| 94 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.10033986 |
| 95 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.09638213 |
| 96 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.09632854 |
| 97 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.09270393 |
| 98 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.08880936 |
| 99 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.08242925 |
| 100 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.07686206 |
| 101 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.07471114 |
| 102 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.07070494 |
| 103 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.05149511 |
| 104 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.05126006 |
| 105 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.04705644 |
| 106 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04557819 |
| 107 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.03604981 |
| 108 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.03422358 |
| 109 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.03135456 |
| 110 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.01623660 |
| 111 | * TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.01455455 |
| 112 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.98389629 |
| 113 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.98113008 |
| 114 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.97195033 |
| 115 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.96350287 |
| 116 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.95322162 |
| 117 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.94382931 |
| 118 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.92244521 |
| 119 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.90751424 |
| 120 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.89024345 |
| 121 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.88852511 |
| 122 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.87513137 |
| 123 | * CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.84874781 |
| 124 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.82327104 |
| 125 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.81987025 |
| 126 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.81272364 |
| 127 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.78139379 |
| 128 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.77382443 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 5.52439229 |
| 2 | MP0003693_abnormal_embryo_hatching | 3.32929152 |
| 3 | MP0010094_abnormal_chromosome_stability | 3.21511616 |
| 4 | MP0009278_abnormal_bone_marrow | 3.15235924 |
| 5 | MP0009379_abnormal_foot_pigmentation | 3.08340167 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 2.86900612 |
| 7 | MP0008058_abnormal_DNA_repair | 2.66959133 |
| 8 | MP0001545_abnormal_hematopoietic_system | 2.58225525 |
| 9 | MP0005397_hematopoietic_system_phenotyp | 2.58225525 |
| 10 | MP0005171_absent_coat_pigmentation | 2.49760650 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.46949531 |
| 12 | MP0003111_abnormal_nucleus_morphology | 2.44275195 |
| 13 | MP0002009_preneoplasia | 2.38630223 |
| 14 | MP0003077_abnormal_cell_cycle | 2.31826339 |
| 15 | MP0003786_premature_aging | 2.31548345 |
| 16 | MP0005174_abnormal_tail_pigmentation | 2.11880796 |
| 17 | MP0006035_abnormal_mitochondrial_morpho | 2.10638105 |
| 18 | MP0005075_abnormal_melanosome_morpholog | 2.07677440 |
| 19 | MP0000490_abnormal_crypts_of | 2.04518449 |
| 20 | MP0010030_abnormal_orbit_morphology | 2.01660426 |
| 21 | MP0002938_white_spotting | 1.98208480 |
| 22 | MP0008995_early_reproductive_senescence | 1.97390492 |
| 23 | MP0002234_abnormal_pharynx_morphology | 1.94033420 |
| 24 | MP0003123_paternal_imprinting | 1.89840070 |
| 25 | MP0002736_abnormal_nociception_after | 1.89658510 |
| 26 | MP0000685_abnormal_immune_system | 1.89503528 |
| 27 | MP0008932_abnormal_embryonic_tissue | 1.82809345 |
| 28 | MP0009333_abnormal_splenocyte_physiolog | 1.82718064 |
| 29 | MP0003718_maternal_effect | 1.76648739 |
| 30 | MP0002132_abnormal_respiratory_system | 1.74884220 |
| 31 | MP0002396_abnormal_hematopoietic_system | 1.74249064 |
| 32 | MP0005408_hypopigmentation | 1.73509331 |
| 33 | MP0003186_abnormal_redox_activity | 1.70320519 |
| 34 | MP0001529_abnormal_vocalization | 1.60239999 |
| 35 | MP0009697_abnormal_copulation | 1.52047736 |
| 36 | MP0002405_respiratory_system_inflammati | 1.51841696 |
| 37 | MP0000015_abnormal_ear_pigmentation | 1.50561372 |
| 38 | MP0003763_abnormal_thymus_physiology | 1.48470695 |
| 39 | MP0008007_abnormal_cellular_replicative | 1.47859413 |
| 40 | MP0001835_abnormal_antigen_presentation | 1.45518659 |
| 41 | MP0006082_CNS_inflammation | 1.44097640 |
| 42 | MP0003806_abnormal_nucleotide_metabolis | 1.43070410 |
| 43 | MP0002160_abnormal_reproductive_system | 1.42750147 |
| 44 | MP0002019_abnormal_tumor_incidence | 1.42428967 |
| 45 | MP0000049_abnormal_middle_ear | 1.42391826 |
| 46 | MP0005058_abnormal_lysosome_morphology | 1.38260655 |
| 47 | MP0000358_abnormal_cell_content/ | 1.33969950 |
| 48 | MP0003656_abnormal_erythrocyte_physiolo | 1.33753039 |
| 49 | MP0008877_abnormal_DNA_methylation | 1.31726255 |
| 50 | MP0003315_abnormal_perineum_morphology | 1.31278245 |
| 51 | MP0000689_abnormal_spleen_morphology | 1.30682157 |
| 52 | MP0001853_heart_inflammation | 1.25620466 |
| 53 | MP0002148_abnormal_hypersensitivity_rea | 1.25231503 |
| 54 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25027635 |
| 55 | MP0001727_abnormal_embryo_implantation | 1.24372096 |
| 56 | MP0002006_tumorigenesis | 1.22988959 |
| 57 | MP0003567_abnormal_fetal_cardiomyocyte | 1.22139907 |
| 58 | MP0002398_abnormal_bone_marrow | 1.21895080 |
| 59 | MP0009785_altered_susceptibility_to | 1.18148615 |
| 60 | MP0004133_heterotaxia | 1.18110332 |
| 61 | MP0001905_abnormal_dopamine_level | 1.17362352 |
| 62 | MP0000313_abnormal_cell_death | 1.16325683 |
| 63 | MP0000350_abnormal_cell_proliferation | 1.15632603 |
| 64 | MP0005670_abnormal_white_adipose | 1.14795560 |
| 65 | MP0002166_altered_tumor_susceptibility | 1.14391938 |
| 66 | MP0005025_abnormal_response_to | 1.14385759 |
| 67 | MP0002722_abnormal_immune_system | 1.13181060 |
| 68 | MP0008789_abnormal_olfactory_epithelium | 1.13005374 |
| 69 | MP0002210_abnormal_sex_determination | 1.11130251 |
| 70 | MP0001697_abnormal_embryo_size | 1.10801462 |
| 71 | MP0000371_diluted_coat_color | 1.09978969 |
| 72 | MP0002822_catalepsy | 1.09561132 |
| 73 | MP0000678_abnormal_parathyroid_gland | 1.09291685 |
| 74 | MP0005671_abnormal_response_to | 1.08110131 |
| 75 | MP0003436_decreased_susceptibility_to | 1.07086473 |
| 76 | MP0000470_abnormal_stomach_morphology | 1.06260290 |
| 77 | MP0001293_anophthalmia | 1.06009882 |
| 78 | MP0005389_reproductive_system_phenotype | 1.04982579 |
| 79 | MP0002653_abnormal_ependyma_morphology | 1.04929218 |
| 80 | MP0001968_abnormal_touch/_nociception | 1.02479307 |
| 81 | MP0002086_abnormal_extraembryonic_tissu | 1.02098110 |
| 82 | MP0001919_abnormal_reproductive_system | 1.01329498 |
| 83 | MP0003453_abnormal_keratinocyte_physiol | 1.01208441 |
| 84 | MP0010155_abnormal_intestine_physiology | 1.00703522 |
| 85 | MP0003890_abnormal_embryonic-extraembry | 0.99777118 |
| 86 | MP0002837_dystrophic_cardiac_calcinosis | 0.99037265 |
| 87 | MP0002429_abnormal_blood_cell | 0.98310657 |
| 88 | MP0005464_abnormal_platelet_physiology | 0.97775571 |
| 89 | MP0000716_abnormal_immune_system | 0.96252760 |
| 90 | MP0003136_yellow_coat_color | 0.95125135 |
| 91 | MP0001730_embryonic_growth_arrest | 0.94920257 |
| 92 | MP0004233_abnormal_muscle_weight | 0.94549310 |
| 93 | MP0005332_abnormal_amino_acid | 0.92895442 |
| 94 | MP0002277_abnormal_respiratory_mucosa | 0.92581600 |
| 95 | MP0002452_abnormal_antigen_presenting | 0.92425988 |
| 96 | MP0003937_abnormal_limbs/digits/tail_de | 0.91823947 |
| 97 | MP0002249_abnormal_larynx_morphology | 0.91781087 |
| 98 | MP0005501_abnormal_skin_physiology | 0.91309063 |
| 99 | MP0010352_gastrointestinal_tract_polyps | 0.90577486 |
| 100 | MP0002095_abnormal_skin_pigmentation | 0.90550051 |
| 101 | MP0006072_abnormal_retinal_apoptosis | 0.90543731 |
| 102 | MP0000566_synostosis | 0.90439634 |
| 103 | MP0000537_abnormal_urethra_morphology | 0.90092447 |
| 104 | MP0001800_abnormal_humoral_immune | 0.90085803 |
| 105 | MP0002163_abnormal_gland_morphology | 0.90011497 |
| 106 | MP0002723_abnormal_immune_serum | 0.89587993 |
| 107 | MP0002420_abnormal_adaptive_immunity | 0.89548912 |
| 108 | MP0001346_abnormal_lacrimal_gland | 0.89436426 |
| 109 | MP0001819_abnormal_immune_cell | 0.89060983 |
| 110 | MP0001672_abnormal_embryogenesis/_devel | 0.88767368 |
| 111 | MP0005380_embryogenesis_phenotype | 0.88767368 |
| 112 | MP0006036_abnormal_mitochondrial_physio | 0.88007598 |
| 113 | MP0003172_abnormal_lysosome_physiology | 0.87623477 |
| 114 | MP0001929_abnormal_gametogenesis | 0.87477979 |
| 115 | MP0003646_muscle_fatigue | 0.86655850 |
| 116 | MP0002282_abnormal_trachea_morphology | 0.86393643 |
| 117 | MP0000703_abnormal_thymus_morphology | 0.86362679 |
| 118 | MP0001881_abnormal_mammary_gland | 0.85872818 |
| 119 | MP0003724_increased_susceptibility_to | 0.85825753 |
| 120 | MP0005266_abnormal_metabolism | 0.85436232 |
| 121 | MP0004147_increased_porphyrin_level | 0.85350215 |
| 122 | MP0002085_abnormal_embryonic_tissue | 0.84034849 |
| 123 | MP0001764_abnormal_homeostasis | 0.83924208 |
| 124 | MP0005000_abnormal_immune_tolerance | 0.83825297 |
| 125 | MP0002080_prenatal_lethality | 0.82462075 |
| 126 | MP0001186_pigmentation_phenotype | 0.81998165 |
| 127 | MP0000653_abnormal_sex_gland | 0.81693566 |
| 128 | MP0002419_abnormal_innate_immunity | 0.81162806 |
| 129 | MP0003828_pulmonary_edema | 0.81046563 |
| 130 | MP0001119_abnormal_female_reproductive | 0.80686725 |
| 131 | MP0010307_abnormal_tumor_latency | 0.79864176 |
| 132 | MP0003121_genomic_imprinting | 0.77588940 |
| 133 | MP0002102_abnormal_ear_morphology | 0.77472091 |
| 134 | MP0002697_abnormal_eye_size | 0.77321776 |
| 135 | MP0005499_abnormal_olfactory_system | 0.76266049 |
| 136 | MP0005394_taste/olfaction_phenotype | 0.76266049 |
| 137 | MP0002075_abnormal_coat/hair_pigmentati | 0.75667232 |
| 138 | MP0001661_extended_life_span | 0.74558254 |
| 139 | MP0005377_hearing/vestibular/ear_phenot | 0.73603419 |
| 140 | MP0003878_abnormal_ear_physiology | 0.73603419 |
| 141 | MP0002111_abnormal_tail_morphology | 0.73566506 |
| 142 | MP0002084_abnormal_developmental_patter | 0.72582126 |
| 143 | MP0001145_abnormal_male_reproductive | 0.72027923 |
| 144 | MP0003941_abnormal_skin_development | 0.72027428 |
| 145 | MP0006292_abnormal_olfactory_placode | 0.70344047 |
| 146 | MP0008872_abnormal_physiological_respon | 0.70153631 |
| 147 | MP0003011_delayed_dark_adaptation | 0.70117829 |
| 148 | MP0004197_abnormal_fetal_growth/weight/ | 0.68854571 |
| 149 | MP0001873_stomach_inflammation | 0.68025788 |
| 150 | MP0003938_abnormal_ear_development | 0.66753485 |
| 151 | MP0001845_abnormal_inflammatory_respons | 0.66607468 |
| 152 | MP0003137_abnormal_impulse_conducting | 0.64817287 |
| 153 | MP0009672_abnormal_birth_weight | 0.64761188 |
| 154 | MP0005646_abnormal_pituitary_gland | 0.64608061 |
| 155 | MP0002177_abnormal_outer_ear | 0.64243908 |
| 156 | MP0003698_abnormal_male_reproductive | 0.61989500 |
| 157 | MP0005330_cardiomyopathy | 0.61732040 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.96645275 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.94913327 |
| 3 | Acute encephalopathy (HP:0006846) | 5.39841169 |
| 4 | Mitochondrial inheritance (HP:0001427) | 5.38488691 |
| 5 | Increased CSF lactate (HP:0002490) | 4.90754445 |
| 6 | Progressive macrocephaly (HP:0004481) | 4.80708324 |
| 7 | Hepatocellular necrosis (HP:0001404) | 4.78612488 |
| 8 | Increased IgM level (HP:0003496) | 4.61394804 |
| 9 | Pustule (HP:0200039) | 4.51963832 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 4.33220331 |
| 11 | Hepatic necrosis (HP:0002605) | 4.32914934 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 4.05828832 |
| 13 | Renal Fanconi syndrome (HP:0001994) | 4.05741333 |
| 14 | Cerebral edema (HP:0002181) | 4.03530995 |
| 15 | Increased intramyocellular lipid droplets (HP:0012240) | 4.01297448 |
| 16 | Poikiloderma (HP:0001029) | 3.86599572 |
| 17 | Concave nail (HP:0001598) | 3.79485998 |
| 18 | Abnormal number of erythroid precursors (HP:0012131) | 3.74222769 |
| 19 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.73648427 |
| 20 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 3.62228979 |
| 21 | Rectal fistula (HP:0100590) | 3.61072253 |
| 22 | Rectovaginal fistula (HP:0000143) | 3.61072253 |
| 23 | Rib fusion (HP:0000902) | 3.59322293 |
| 24 | Lactic acidosis (HP:0003128) | 3.49808511 |
| 25 | Increased muscle lipid content (HP:0009058) | 3.49446004 |
| 26 | Increased serum lactate (HP:0002151) | 3.45398738 |
| 27 | Exertional dyspnea (HP:0002875) | 3.42965002 |
| 28 | Tongue fasciculations (HP:0001308) | 3.39322966 |
| 29 | Reticulocytopenia (HP:0001896) | 3.32262013 |
| 30 | Exercise intolerance (HP:0003546) | 3.29322199 |
| 31 | Abnormal hemoglobin (HP:0011902) | 3.24761770 |
| 32 | Premature graying of hair (HP:0002216) | 3.23639878 |
| 33 | Vaginal fistula (HP:0004320) | 3.22940177 |
| 34 | Respiratory failure (HP:0002878) | 3.19516458 |
| 35 | Absent thumb (HP:0009777) | 3.15682566 |
| 36 | Microvesicular hepatic steatosis (HP:0001414) | 3.13813549 |
| 37 | Abnormality of male internal genitalia (HP:0000022) | 3.07748601 |
| 38 | Intestinal fistula (HP:0100819) | 3.07547359 |
| 39 | Facial hemangioma (HP:0000329) | 3.02083111 |
| 40 | Muscle fiber atrophy (HP:0100295) | 2.93568848 |
| 41 | Patellar aplasia (HP:0006443) | 2.92538739 |
| 42 | Muscle fibrillation (HP:0010546) | 2.91387838 |
| 43 | Absent radius (HP:0003974) | 2.89347684 |
| 44 | Respiratory difficulties (HP:0002880) | 2.79327329 |
| 45 | Type 2 muscle fiber atrophy (HP:0003554) | 2.76891019 |
| 46 | Alopecia of scalp (HP:0002293) | 2.76543553 |
| 47 | Albinism (HP:0001022) | 2.76002603 |
| 48 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.75172263 |
| 49 | Leukodystrophy (HP:0002415) | 2.73662184 |
| 50 | Intestinal atresia (HP:0011100) | 2.72535867 |
| 51 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.70838020 |
| 52 | Increased serum pyruvate (HP:0003542) | 2.70143996 |
| 53 | Abnormality of glycolysis (HP:0004366) | 2.67444143 |
| 54 | Absent forearm bone (HP:0003953) | 2.66332196 |
| 55 | Aplasia involving forearm bones (HP:0009822) | 2.66332196 |
| 56 | Colon cancer (HP:0003003) | 2.61568776 |
| 57 | Lethargy (HP:0001254) | 2.59783459 |
| 58 | Testicular atrophy (HP:0000029) | 2.58790618 |
| 59 | Annular pancreas (HP:0001734) | 2.58432471 |
| 60 | Squamous cell carcinoma (HP:0002860) | 2.56429675 |
| 61 | Breast hypoplasia (HP:0003187) | 2.56293215 |
| 62 | 3-Methylglutaconic aciduria (HP:0003535) | 2.55224245 |
| 63 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.51635154 |
| 64 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.48470394 |
| 65 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.48265408 |
| 66 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.48265408 |
| 67 | Abnormal protein glycosylation (HP:0012346) | 2.48265408 |
| 68 | Abnormal glycosylation (HP:0012345) | 2.48265408 |
| 69 | Birth length less than 3rd percentile (HP:0003561) | 2.47626728 |
| 70 | Hypochromic microcytic anemia (HP:0004840) | 2.45983053 |
| 71 | Hypochromic anemia (HP:0001931) | 2.45703457 |
| 72 | Optic disc pallor (HP:0000543) | 2.44670346 |
| 73 | Rough bone trabeculation (HP:0100670) | 2.44054046 |
| 74 | Microretrognathia (HP:0000308) | 2.43536634 |
| 75 | IgA deficiency (HP:0002720) | 2.38658149 |
| 76 | Selective tooth agenesis (HP:0001592) | 2.37454989 |
| 77 | Male infertility (HP:0003251) | 2.36455839 |
| 78 | Chromsome breakage (HP:0040012) | 2.30630271 |
| 79 | Redundant skin (HP:0001582) | 2.30536124 |
| 80 | IgG deficiency (HP:0004315) | 2.28379154 |
| 81 | Hypoplasia of the radius (HP:0002984) | 2.27338567 |
| 82 | Amniotic constriction ring (HP:0009775) | 2.25916355 |
| 83 | Abnormality of placental membranes (HP:0011409) | 2.25916355 |
| 84 | Pancytopenia (HP:0001876) | 2.25838799 |
| 85 | Orthostatic hypotension (HP:0001278) | 2.25284560 |
| 86 | Type I transferrin isoform profile (HP:0003642) | 2.24142466 |
| 87 | Methylmalonic aciduria (HP:0012120) | 2.22410737 |
| 88 | Pallor (HP:0000980) | 2.20852036 |
| 89 | Abnormality of renal resorption (HP:0011038) | 2.20534640 |
| 90 | Abnormality of the preputium (HP:0100587) | 2.19771164 |
| 91 | Macrocytic anemia (HP:0001972) | 2.19552498 |
| 92 | Abnormality of the ileum (HP:0001549) | 2.19307318 |
| 93 | Abnormality of T cell physiology (HP:0011840) | 2.18225933 |
| 94 | Hypokinesia (HP:0002375) | 2.18022848 |
| 95 | Meckel diverticulum (HP:0002245) | 2.16825950 |
| 96 | Aplastic anemia (HP:0001915) | 2.15080405 |
| 97 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.14527358 |
| 98 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.14527358 |
| 99 | Oral leukoplakia (HP:0002745) | 2.13766919 |
| 100 | Short humerus (HP:0005792) | 2.13581814 |
| 101 | Emotional lability (HP:0000712) | 2.13291481 |
| 102 | CNS demyelination (HP:0007305) | 2.13180631 |
| 103 | Recurrent abscess formation (HP:0002722) | 2.12697285 |
| 104 | Abnormality of the anterior horn cell (HP:0006802) | 2.12568676 |
| 105 | Degeneration of anterior horn cells (HP:0002398) | 2.12568676 |
| 106 | Acute lymphatic leukemia (HP:0006721) | 2.11716394 |
| 107 | Hyperglycinemia (HP:0002154) | 2.10786020 |
| 108 | Vertebral hypoplasia (HP:0008417) | 2.10388313 |
| 109 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 2.10388313 |
| 110 | IgM deficiency (HP:0002850) | 2.09303736 |
| 111 | Diaphragmatic weakness (HP:0009113) | 2.09290173 |
| 112 | Aplasia of the musculature (HP:0100854) | 2.07076594 |
| 113 | Premature skin wrinkling (HP:0100678) | 2.05466433 |
| 114 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.05225993 |
| 115 | Pulmonary fibrosis (HP:0002206) | 2.03668150 |
| 116 | Ragged-red muscle fibers (HP:0003200) | 2.00006527 |
| 117 | Basal cell carcinoma (HP:0002671) | 1.99748257 |
| 118 | Sclerocornea (HP:0000647) | 1.99407222 |
| 119 | Hyperthyroidism (HP:0000836) | 1.99385097 |
| 120 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.98785574 |
| 121 | Petechiae (HP:0000967) | 1.98740294 |
| 122 | Progressive muscle weakness (HP:0003323) | 1.98555256 |
| 123 | Dicarboxylic aciduria (HP:0003215) | 1.98097876 |
| 124 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.98097876 |
| 125 | Cleft eyelid (HP:0000625) | 1.97588889 |
| 126 | Joint stiffness (HP:0001387) | 1.96674776 |
| 127 | Mucopolysacchariduria (HP:0008155) | 1.96478055 |
| 128 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.96478055 |
| 129 | X-linked dominant inheritance (HP:0001423) | 1.95863296 |
| 130 | Reduced antithrombin III activity (HP:0001976) | 1.95723105 |
| 131 | Spinal muscular atrophy (HP:0007269) | 1.95103178 |
| 132 | Capillary hemangiomas (HP:0005306) | 1.94679669 |
| 133 | Abnormality of methionine metabolism (HP:0010901) | 1.94419111 |
| 134 | Generalized aminoaciduria (HP:0002909) | 1.93240498 |
| 135 | Opisthotonus (HP:0002179) | 1.92171545 |
| 136 | Large for gestational age (HP:0001520) | 1.91407724 |
| 137 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.91236856 |
| 138 | Lymphoma (HP:0002665) | 1.90734433 |
| 139 | Multiple enchondromatosis (HP:0005701) | 1.90623137 |
| 140 | Dysautonomia (HP:0002459) | 1.90558143 |
| 141 | Abnormal number of incisors (HP:0011064) | 1.90176318 |
| 142 | Cheilitis (HP:0100825) | 1.88612284 |
| 143 | Sparse eyelashes (HP:0000653) | 1.86590049 |
| 144 | Hypotrichosis (HP:0001006) | 1.85951852 |
| 145 | Myelodysplasia (HP:0002863) | 1.85847169 |
| 146 | Ulnar bowing (HP:0003031) | 1.85760322 |
| 147 | Carpal bone hypoplasia (HP:0001498) | 1.84601656 |
| 148 | Cerebral hypomyelination (HP:0006808) | 1.83940480 |
| 149 | Abnormal trabecular bone morphology (HP:0100671) | 1.83460704 |
| 150 | Cutaneous melanoma (HP:0012056) | 1.82452285 |
| 151 | Anorexia (HP:0002039) | 1.80506595 |
| 152 | Progressive microcephaly (HP:0000253) | 1.80185238 |
| 153 | Bifid uvula (HP:0000193) | 1.80037595 |
| 154 | Dysostosis multiplex (HP:0000943) | 1.79715155 |
| 155 | Abnormality of urine glucose concentration (HP:0011016) | 1.78217457 |
| 156 | Glycosuria (HP:0003076) | 1.78217457 |
| 157 | Popliteal pterygium (HP:0009756) | 1.76696097 |
| 158 | Hyperphosphaturia (HP:0003109) | 1.75251696 |
| 159 | Short chin (HP:0000331) | 1.74933813 |
| 160 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.74825550 |
| 161 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.73538830 |
| 162 | Blindness (HP:0000618) | 1.73250754 |
| 163 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.72899226 |
| 164 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.72899226 |
| 165 | Facial cleft (HP:0002006) | 1.70447332 |
| 166 | Truncus arteriosus (HP:0001660) | 1.67522227 |
| 167 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.67323749 |
| 168 | Abnormality of serum amino acid levels (HP:0003112) | 1.66031606 |
| 169 | Methylmalonic acidemia (HP:0002912) | 1.64208918 |
| 170 | Megaloblastic anemia (HP:0001889) | 1.62364431 |
| 171 | Horseshoe kidney (HP:0000085) | 1.62122829 |
| 172 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.59198125 |
| 173 | Triphalangeal thumb (HP:0001199) | 1.58870384 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 6.33919577 |
| 2 | MAPK15 | 3.88452445 |
| 3 | PIM2 | 3.66640103 |
| 4 | ICK | 3.50563035 |
| 5 | MAP3K6 | 3.40662713 |
| 6 | MAP3K11 | 3.19254298 |
| 7 | PINK1 | 2.88790339 |
| 8 | DDR2 | 2.83538950 |
| 9 | BUB1 | 2.78033310 |
| 10 | NME2 | 2.71982528 |
| 11 | NME1 | 2.48051630 |
| 12 | MATK | 2.46794979 |
| 13 | WEE1 | 2.35443554 |
| 14 | TAF1 | 2.17322039 |
| 15 | CDK7 | 2.09000436 |
| 16 | YES1 | 2.08584435 |
| 17 | DAPK1 | 2.01075946 |
| 18 | SMG1 | 1.92969064 |
| 19 | PIM1 | 1.89237519 |
| 20 | NUAK1 | 1.78428869 |
| 21 | STK16 | 1.77664084 |
| 22 | CSK | 1.70244140 |
| 23 | FGR | 1.67005628 |
| 24 | NEK1 | 1.65162505 |
| 25 | VRK1 | 1.51368310 |
| 26 | PLK3 | 1.51332278 |
| 27 | DYRK3 | 1.48739806 |
| 28 | TESK1 | 1.44113437 |
| 29 | UHMK1 | 1.40864742 |
| 30 | DYRK1B | 1.38837338 |
| 31 | PLK1 | 1.37928879 |
| 32 | IRAK4 | 1.35659432 |
| 33 | TRPM7 | 1.33731779 |
| 34 | MAP3K12 | 1.31437318 |
| 35 | CSNK1G3 | 1.31370017 |
| 36 | PLK4 | 1.28167648 |
| 37 | BMX | 1.24608668 |
| 38 | MAP4K1 | 1.24332083 |
| 39 | LIMK1 | 1.24197954 |
| 40 | TLK1 | 1.23932067 |
| 41 | EIF2AK1 | 1.23354350 |
| 42 | CHEK2 | 1.22117089 |
| 43 | PRKD2 | 1.17035382 |
| 44 | RPS6KL1 | 1.15441453 |
| 45 | RPS6KC1 | 1.15441453 |
| 46 | KDR | 1.12459378 |
| 47 | AKT3 | 1.12239463 |
| 48 | IRAK3 | 1.11187808 |
| 49 | CCNB1 | 1.08950278 |
| 50 | RPS6KA6 | 1.07252121 |
| 51 | ILK | 1.05752424 |
| 52 | CDC7 | 1.05093447 |
| 53 | IKBKB | 1.04948111 |
| 54 | ATR | 1.03005833 |
| 55 | BLK | 1.01462042 |
| 56 | CDK8 | 1.00495009 |
| 57 | TYRO3 | 0.99600317 |
| 58 | CSNK1A1L | 0.99298338 |
| 59 | CDK6 | 0.98191340 |
| 60 | RPS6KB2 | 0.97737168 |
| 61 | SRPK1 | 0.97668003 |
| 62 | CSNK1G1 | 0.97001087 |
| 63 | BRSK2 | 0.96808217 |
| 64 | PDK2 | 0.95920024 |
| 65 | ACVR1B | 0.93133217 |
| 66 | AURKB | 0.92834951 |
| 67 | NEK2 | 0.92178503 |
| 68 | CSNK1G2 | 0.91484736 |
| 69 | EIF2AK3 | 0.90635738 |
| 70 | LYN | 0.88775157 |
| 71 | MAPK11 | 0.88234918 |
| 72 | TSSK6 | 0.86263583 |
| 73 | TESK2 | 0.84419977 |
| 74 | CSNK2A1 | 0.84178191 |
| 75 | TAOK2 | 0.83755863 |
| 76 | DYRK2 | 0.83589480 |
| 77 | TRIM28 | 0.82653799 |
| 78 | AURKA | 0.80851468 |
| 79 | ARAF | 0.80812403 |
| 80 | MAP3K10 | 0.79546657 |
| 81 | PAK4 | 0.78905373 |
| 82 | LRRK2 | 0.78353454 |
| 83 | EPHA2 | 0.77808541 |
| 84 | PRKCI | 0.77533910 |
| 85 | DAPK3 | 0.76790620 |
| 86 | MAP2K7 | 0.75420070 |
| 87 | MST4 | 0.74365415 |
| 88 | SCYL2 | 0.72295416 |
| 89 | TXK | 0.72098143 |
| 90 | BCKDK | 0.69128096 |
| 91 | RPS6KA5 | 0.68776604 |
| 92 | MAPKAPK5 | 0.67510944 |
| 93 | PRKD3 | 0.67254357 |
| 94 | TTK | 0.64242459 |
| 95 | MST1R | 0.63814280 |
| 96 | ZAK | 0.60552721 |
| 97 | ERBB3 | 0.57436000 |
| 98 | PBK | 0.57415578 |
| 99 | MAPKAPK3 | 0.57040765 |
| 100 | RAF1 | 0.56541216 |
| 101 | GSK3A | 0.56131318 |
| 102 | CSNK2A2 | 0.56101938 |
| 103 | RPS6KA1 | 0.55995827 |
| 104 | STK4 | 0.55774963 |
| 105 | ABL2 | 0.55290153 |
| 106 | MAP4K2 | 0.54543802 |
| 107 | PAK1 | 0.54055605 |
| 108 | GRK5 | 0.53200103 |
| 109 | TYK2 | 0.51394863 |
| 110 | BTK | 0.51362275 |
| 111 | BRSK1 | 0.48839520 |
| 112 | MAPK4 | 0.48431805 |
| 113 | TEC | 0.46538161 |
| 114 | CDK4 | 0.46299962 |
| 115 | ZAP70 | 0.46254620 |
| 116 | CDK2 | 0.45562438 |
| 117 | TBK1 | 0.44817160 |
| 118 | MAPKAPK2 | 0.43235432 |
| 119 | BRAF | 0.42688437 |
| 120 | STK10 | 0.42493111 |
| 121 | LCK | 0.42075406 |
| 122 | CHUK | 0.40906971 |
| 123 | PRKCD | 0.40188895 |
| 124 | CHEK1 | 0.39258292 |
| 125 | MUSK | 0.38621470 |
| 126 | ATM | 0.38165604 |
| 127 | WNK3 | 0.37100353 |
| 128 | KIT | 0.37054649 |
| 129 | EIF2AK2 | 0.36991527 |
| 130 | RPS6KA4 | 0.36442744 |
| 131 | AKT2 | 0.36195776 |
| 132 | MAPK3 | 0.35842439 |
| 133 | HIPK2 | 0.35806028 |
| 134 | TIE1 | 0.35414107 |
| 135 | MAP3K8 | 0.33300204 |
| 136 | CAMK2G | 0.32992007 |
| 137 | CDC42BPA | 0.31818256 |
| 138 | PDGFRA | 0.31812445 |
| 139 | CDK1 | 0.30419643 |
| 140 | CDK11A | 0.30124790 |
| 141 | CDK18 | 0.29692762 |
| 142 | CDK15 | 0.29162792 |
| 143 | CDK14 | 0.28511996 |
| 144 | BMPR1B | 0.28246959 |
| 145 | EPHB2 | 0.26982410 |
| 146 | CSNK1A1 | 0.26305340 |
| 147 | CDK9 | 0.24833845 |
| 148 | CSNK1E | 0.24287042 |
| 149 | IRAK2 | 0.21319659 |
| 150 | MINK1 | 0.18007071 |
| 151 | CAMK2D | 0.17820444 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 4.67381201 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 4.58828556 |
| 3 | Base excision repair_Homo sapiens_hsa03410 | 4.15172785 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.93736024 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.29240267 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.82852776 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.75661261 |
| 8 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.72574119 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.71719064 |
| 10 | Spliceosome_Homo sapiens_hsa03040 | 2.59307344 |
| 11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.08468404 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 2.05952996 |
| 13 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.82391170 |
| 14 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.78544215 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.66389000 |
| 16 | Cell cycle_Homo sapiens_hsa04110 | 1.62786403 |
| 17 | Sulfur relay system_Homo sapiens_hsa04122 | 1.59598450 |
| 18 | * Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.59586740 |
| 19 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.58506768 |
| 20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.54169899 |
| 21 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.50663345 |
| 22 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.47833996 |
| 23 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.34545444 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34231132 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.32197073 |
| 26 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.30287409 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.29066239 |
| 28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.20637402 |
| 29 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.20384956 |
| 30 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.20300104 |
| 31 | Parkinsons disease_Homo sapiens_hsa05012 | 1.14765071 |
| 32 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.12315957 |
| 33 | Protein export_Homo sapiens_hsa03060 | 1.07653590 |
| 34 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.06577026 |
| 35 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.03703797 |
| 36 | Carbon metabolism_Homo sapiens_hsa01200 | 1.03145096 |
| 37 | Legionellosis_Homo sapiens_hsa05134 | 1.02619005 |
| 38 | Huntingtons disease_Homo sapiens_hsa05016 | 1.01047937 |
| 39 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.99265152 |
| 40 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.97455541 |
| 41 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.97302517 |
| 42 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.96121448 |
| 43 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.92683308 |
| 44 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.91298873 |
| 45 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.90526882 |
| 46 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.89410718 |
| 47 | Purine metabolism_Homo sapiens_hsa00230 | 0.84388348 |
| 48 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.83952824 |
| 49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.82805787 |
| 50 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.82345302 |
| 51 | Shigellosis_Homo sapiens_hsa05131 | 0.80436061 |
| 52 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.79530266 |
| 53 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.76609646 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.75565007 |
| 55 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.73119566 |
| 56 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.72598743 |
| 57 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.72255238 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.69405867 |
| 59 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.69354931 |
| 60 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.67988905 |
| 61 | Allograft rejection_Homo sapiens_hsa05330 | 0.67505003 |
| 62 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.65223524 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.63724017 |
| 64 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.63575953 |
| 65 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.63340792 |
| 66 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.63307669 |
| 67 | Measles_Homo sapiens_hsa05162 | 0.63244826 |
| 68 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.62047982 |
| 69 | Circadian rhythm_Homo sapiens_hsa04710 | 0.60986961 |
| 70 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.59140504 |
| 71 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.54177822 |
| 72 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.52774302 |
| 73 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.50684188 |
| 74 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.50634246 |
| 75 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.49600781 |
| 76 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.49138699 |
| 77 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.49055562 |
| 78 | Galactose metabolism_Homo sapiens_hsa00052 | 0.47587691 |
| 79 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.47463537 |
| 80 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45815143 |
| 81 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.44948734 |
| 82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44518943 |
| 83 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.44452519 |
| 84 | Alzheimers disease_Homo sapiens_hsa05010 | 0.43884989 |
| 85 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.43387654 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.41250845 |
| 87 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.41246836 |
| 88 | Other glycan degradation_Homo sapiens_hsa00511 | 0.39477572 |
| 89 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.38682220 |
| 90 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.38205853 |
| 91 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.38053483 |
| 92 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.38017312 |
| 93 | Asthma_Homo sapiens_hsa05310 | 0.37686228 |
| 94 | Leishmaniasis_Homo sapiens_hsa05140 | 0.34642654 |
| 95 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.33267770 |
| 96 | Apoptosis_Homo sapiens_hsa04210 | 0.32560967 |
| 97 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.32196373 |
| 98 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.31946293 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.31727254 |
| 100 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.31570997 |
| 101 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.31432274 |
| 102 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.30610953 |
| 103 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.30393787 |
| 104 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.28255871 |
| 105 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.28040801 |
| 106 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.27923757 |
| 107 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.27282192 |
| 108 | Lysosome_Homo sapiens_hsa04142 | 0.27191294 |
| 109 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.26558424 |
| 110 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.26378345 |
| 111 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.26332761 |
| 112 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.26237518 |
| 113 | HTLV-I infection_Homo sapiens_hsa05166 | 0.24466910 |
| 114 | Viral myocarditis_Homo sapiens_hsa05416 | 0.23779752 |
| 115 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.23643779 |
| 116 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.22587140 |
| 117 | Bladder cancer_Homo sapiens_hsa05219 | 0.21573679 |
| 118 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.21504409 |
| 119 | Hepatitis B_Homo sapiens_hsa05161 | 0.21389545 |
| 120 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.20327997 |
| 121 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.20165037 |
| 122 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.19760808 |
| 123 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.19699593 |
| 124 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.19040382 |
| 125 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.18921552 |
| 126 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.18446876 |
| 127 | Adherens junction_Homo sapiens_hsa04520 | 0.18047232 |
| 128 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.17829533 |
| 129 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.17533592 |
| 130 | Alcoholism_Homo sapiens_hsa05034 | 0.17114967 |
| 131 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.16559229 |
| 132 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.12401736 |
| 133 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.12353838 |
| 134 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.12311958 |
| 135 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.11371573 |
| 136 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.09548535 |
| 137 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.09411679 |
| 138 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.05181635 |
| 139 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.04471232 |

