STRAP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.26979729
2protein localization to kinetochore (GO:0034501)5.04688366
3folic acid-containing compound biosynthetic process (GO:0009396)4.85513546
4establishment of integrated proviral latency (GO:0075713)4.65241825
5formation of translation preinitiation complex (GO:0001731)4.59663397
6nucleobase biosynthetic process (GO:0046112)4.58659874
7ribosome assembly (GO:0042255)4.54615609
8regulation of translational termination (GO:0006449)4.48640717
9mitotic nuclear envelope disassembly (GO:0007077)4.47836086
10DNA replication initiation (GO:0006270)4.43074981
11purine nucleobase biosynthetic process (GO:0009113)4.42001361
12nuclear pore organization (GO:0006999)4.34881573
13DNA replication-dependent nucleosome organization (GO:0034723)4.33755913
14DNA replication-dependent nucleosome assembly (GO:0006335)4.33755913
15protein localization to chromosome, centromeric region (GO:0071459)4.32902450
16proteasome assembly (GO:0043248)4.31994748
17cullin deneddylation (GO:0010388)4.29687267
18nuclear envelope disassembly (GO:0051081)4.27440573
19membrane disassembly (GO:0030397)4.27440573
20DNA strand elongation involved in DNA replication (GO:0006271)4.24126236
21mitotic metaphase plate congression (GO:0007080)4.21031252
22IMP biosynthetic process (GO:0006188)4.11238852
23nuclear pore complex assembly (GO:0051292)4.02664405
24DNA strand elongation (GO:0022616)3.99596656
25protein deneddylation (GO:0000338)3.96729841
26regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.90980042
27DNA replication checkpoint (GO:0000076)3.85783510
28establishment of viral latency (GO:0019043)3.84248107
29IMP metabolic process (GO:0046040)3.83302832
30folic acid metabolic process (GO:0046655)3.75849176
31ribosome biogenesis (GO:0042254)3.72420259
32DNA damage response, detection of DNA damage (GO:0042769)3.62384945
33regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.60132186
34regulation of translational fidelity (GO:0006450)3.56684117
35negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.54355685
36nuclear envelope organization (GO:0006998)3.54296441
37mitotic chromosome condensation (GO:0007076)3.52976603
38regulation of spindle organization (GO:0090224)3.51937034
39metaphase plate congression (GO:0051310)3.48623550
40maturation of SSU-rRNA (GO:0030490)3.39069299
41L-serine metabolic process (GO:0006563)3.38817821
42telomere maintenance via semi-conservative replication (GO:0032201)3.38679452
43DNA replication-independent nucleosome assembly (GO:0006336)3.37462035
44DNA replication-independent nucleosome organization (GO:0034724)3.37462035
45positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.36492950
46regulation of RNA export from nucleus (GO:0046831)3.36019294
47chromatin remodeling at centromere (GO:0031055)3.34248531
48peptidyl-arginine omega-N-methylation (GO:0035247)3.32043616
49DNA duplex unwinding (GO:0032508)3.31106436
50CENP-A containing nucleosome assembly (GO:0034080)3.29793333
51chaperone-mediated protein complex assembly (GO:0051131)3.29187660
52DNA geometric change (GO:0032392)3.29083661
53negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.24365671
54negative regulation of ligase activity (GO:0051352)3.24365671
55protein localization to chromosome (GO:0034502)3.22670942
56negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.22042870
57regulation of chromosome segregation (GO:0051983)3.19290714
58negative regulation of chromosome segregation (GO:0051985)3.17867150
59sister chromatid segregation (GO:0000819)3.17573058
60mitotic sister chromatid cohesion (GO:0007064)3.17020909
61mitotic spindle checkpoint (GO:0071174)3.16958180
62spindle checkpoint (GO:0031577)3.16832346
63tRNA aminoacylation (GO:0043039)3.16717925
64amino acid activation (GO:0043038)3.16717925
65mitotic sister chromatid segregation (GO:0000070)3.16512914
66positive regulation of chromosome segregation (GO:0051984)3.15345541
67negative regulation of mitotic sister chromatid separation (GO:2000816)3.14897732
68negative regulation of mitotic sister chromatid segregation (GO:0033048)3.14897732
69negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.14897732
70negative regulation of sister chromatid segregation (GO:0033046)3.14897732
71mitotic G1 DNA damage checkpoint (GO:0031571)3.14896852
72translesion synthesis (GO:0019985)3.13899776
73mitotic spindle assembly checkpoint (GO:0007094)3.13499684
74DNA double-strand break processing (GO:0000729)3.12935445
75spindle assembly checkpoint (GO:0071173)3.11463796
76DNA deamination (GO:0045006)3.09766279
77histone exchange (GO:0043486)3.09600621
78translational initiation (GO:0006413)3.08340800
79ribonucleoprotein complex biogenesis (GO:0022613)3.07353550
80chromatin assembly or disassembly (GO:0006333)3.04707601
81negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.03725617
82protein complex localization (GO:0031503)3.03668850
83regulation of centrosome cycle (GO:0046605)3.03175893
84mitotic recombination (GO:0006312)3.03090302
85establishment of chromosome localization (GO:0051303)3.01617911
86de novo protein folding (GO:0006458)2.98540870
87regulation of mitotic metaphase/anaphase transition (GO:0030071)2.98508279
88telomere maintenance via recombination (GO:0000722)2.97074019
89peptidyl-arginine N-methylation (GO:0035246)2.96779410
90peptidyl-arginine methylation (GO:0018216)2.96779410
91regulation of cellular amino acid metabolic process (GO:0006521)2.96552919
92positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.96097033
93pre-miRNA processing (GO:0031054)2.95358142
94histone-serine phosphorylation (GO:0035404)2.95313668
95non-recombinational repair (GO:0000726)2.94656054
96double-strand break repair via nonhomologous end joining (GO:0006303)2.94656054
97heterochromatin organization (GO:0070828)2.93801118
98L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.93553824
99* spliceosomal snRNP assembly (GO:0000387)2.93443834
100establishment of protein localization to mitochondrial membrane (GO:0090151)2.93372187
101negative regulation of RNA splicing (GO:0033119)2.93192695
102pore complex assembly (GO:0046931)2.91934366
103regulation of mitotic spindle organization (GO:0060236)2.90625129
104regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.90247769
105regulation of translational elongation (GO:0006448)2.90092814
106postreplication repair (GO:0006301)2.88565419
107anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.86576464
108regulation of helicase activity (GO:0051095)2.85677974
109attachment of spindle microtubules to kinetochore (GO:0008608)2.84908331
110regulation of translational initiation (GO:0006446)2.83630275
111de novo posttranslational protein folding (GO:0051084)2.83174773
112telomere maintenance via telomere lengthening (GO:0010833)2.82541122
113positive regulation of ligase activity (GO:0051351)2.80474633
114protein neddylation (GO:0045116)2.80276493
115DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.80191419
116signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.80188955
117signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.80188955
118signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.80188955
119histone H2A acetylation (GO:0043968)2.79950093
120mRNA splicing, via spliceosome (GO:0000398)2.79729420
121RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.79729420
122pteridine-containing compound biosynthetic process (GO:0042559)2.79569030
123signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.78714821
124intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.78714821
125regulation of ubiquitin-protein transferase activity (GO:0051438)2.78613057
126tRNA aminoacylation for protein translation (GO:0006418)2.78485532
127rRNA processing (GO:0006364)2.78161089
128regulation of mitotic spindle checkpoint (GO:1903504)2.77649699
129regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.77649699
130regulation of mitochondrial translation (GO:0070129)2.77261307
131RNA splicing, via transesterification reactions (GO:0000375)2.77201871
132regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.76637938
133signal transduction involved in cell cycle checkpoint (GO:0072395)2.76387267
134glycine metabolic process (GO:0006544)2.76345316
135ATP-dependent chromatin remodeling (GO:0043044)2.76253267
1367-methylguanosine mRNA capping (GO:0006370)2.75728770
137G1 DNA damage checkpoint (GO:0044783)2.75671068
138G1/S transition of mitotic cell cycle (GO:0000082)2.75523785
139mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.74814444
140signal transduction involved in DNA damage checkpoint (GO:0072422)2.74363768
141signal transduction involved in DNA integrity checkpoint (GO:0072401)2.74363768
142peptidyl-histidine modification (GO:0018202)2.73394913
143DNA ligation (GO:0006266)2.72127183
144termination of RNA polymerase III transcription (GO:0006386)2.71648853
145transcription elongation from RNA polymerase III promoter (GO:0006385)2.71648853
146RNA capping (GO:0036260)2.67152251
1477-methylguanosine RNA capping (GO:0009452)2.67152251
148regulation of ligase activity (GO:0051340)2.66143726
149protein K11-linked ubiquitination (GO:0070979)2.65485405
150protein targeting to mitochondrion (GO:0006626)2.62645669
151positive regulation of mitochondrial fission (GO:0090141)2.57156492
152mitochondrial RNA metabolic process (GO:0000959)2.56994335
153protein localization to mitochondrion (GO:0070585)2.56102978
154termination of RNA polymerase II transcription (GO:0006369)2.55627745
155histone mRNA metabolic process (GO:0008334)2.53465616
156DNA catabolic process, exonucleolytic (GO:0000738)2.51020245
157histone arginine methylation (GO:0034969)2.50969238
158chaperone-mediated protein transport (GO:0072321)2.50514971

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.05498927
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.38689869
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.19415494
4FOXM1_23109430_ChIP-Seq_U2OS_Human4.09401399
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.38868102
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.05278050
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.79181900
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.76318741
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.75252495
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.71542071
11AR_21909140_ChIP-Seq_LNCAP_Human2.69562204
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.53580521
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.52900450
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.50043477
15NELFA_20434984_ChIP-Seq_ESCs_Mouse2.43683146
16XRN2_22483619_ChIP-Seq_HELA_Human2.41841678
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.34244895
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.32225339
19EST1_17652178_ChIP-ChIP_JURKAT_Human2.28298575
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.26140209
21MYCN_18555785_ChIP-Seq_MESCs_Mouse2.07834484
22MYC_22102868_ChIP-Seq_BL_Human2.03729427
23E2F1_21310950_ChIP-Seq_MCF-7_Human2.00909598
24ZFX_18555785_ChIP-Seq_MESCs_Mouse1.98982363
25DCP1A_22483619_ChIP-Seq_HELA_Human1.94220270
26* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.94031002
27PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.92033442
28GABP_19822575_ChIP-Seq_HepG2_Human1.90930620
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.89937290
30VDR_23849224_ChIP-Seq_CD4+_Human1.89197118
31E2F1_18555785_ChIP-Seq_MESCs_Mouse1.86219811
32SALL1_21062744_ChIP-ChIP_HESCs_Human1.83406171
33PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.80094250
34CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.73884751
35TTF2_22483619_ChIP-Seq_HELA_Human1.67841237
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.67462283
37ZNF263_19887448_ChIP-Seq_K562_Human1.63609282
38FOXP3_21729870_ChIP-Seq_TREG_Human1.63506033
39* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.59077703
40* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.57357566
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.57139368
42RBPJ_22232070_ChIP-Seq_NCS_Mouse1.56708109
43KLF4_18555785_ChIP-Seq_MESCs_Mouse1.56583906
44KDM5A_27292631_Chip-Seq_BREAST_Human1.56210780
45CIITA_25753668_ChIP-Seq_RAJI_Human1.55589308
46STAT3_1855785_ChIP-Seq_MESCs_Mouse1.48013419
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.47806877
48DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.47430582
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.46146857
50CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.45485853
51* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.44063885
52* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.41299511
53CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.39361171
54YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.38076257
55POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.37482289
56NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.33839520
57NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.33401602
58ZNF274_21170338_ChIP-Seq_K562_Hela1.31296983
59NANOG_16153702_ChIP-ChIP_HESCs_Human1.30869833
60ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.29270971
61FUS_26573619_Chip-Seq_HEK293_Human1.27531617
62* EWS_26573619_Chip-Seq_HEK293_Human1.27392572
63ELK1_19687146_ChIP-ChIP_HELA_Human1.26142859
64E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25999253
65CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.25178632
66TFEB_21752829_ChIP-Seq_HELA_Human1.24587738
67* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.24513538
68ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24411819
69IGF1R_20145208_ChIP-Seq_DFB_Human1.24178685
70ELF1_17652178_ChIP-ChIP_JURKAT_Human1.23190218
71SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.22807330
72E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.21914480
73NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.20987121
74POU5F1_16153702_ChIP-ChIP_HESCs_Human1.19308370
75SOX2_16153702_ChIP-ChIP_HESCs_Human1.18837760
76ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.18161977
77TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.16875159
78SOX17_20123909_ChIP-Seq_XEN_Mouse1.16276767
79* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.14121260
80SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.13974038
81DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13298883
82* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.12099518
83ESR1_15608294_ChIP-ChIP_MCF-7_Human1.11143347
84PADI4_21655091_ChIP-ChIP_MCF-7_Human1.10062748
85FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09967722
86CLOCK_20551151_ChIP-Seq_293T_Human1.08169596
87YY1_21170310_ChIP-Seq_MESCs_Mouse1.07876602
88KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.07847638
89POU3F2_20337985_ChIP-ChIP_501MEL_Human1.07568063
90TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05216723
91CHD1_26751641_Chip-Seq_LNCaP_Human1.05146942
92TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.04631552
93* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.04480991
94* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.03756431
95ATF3_27146783_Chip-Seq_COLON_Human1.02495709
96TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02428786
97ELK1_22589737_ChIP-Seq_MCF10A_Human1.02293331
98CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.00898671
99VDR_21846776_ChIP-Seq_THP-1_Human1.00646442
100NANOG_21062744_ChIP-ChIP_HESCs_Human0.97598662
101* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.95535556
102FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.94590296
103CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.93918164
104CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.93808842
105TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93574292
106* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93233520
107SOX2_18555785_ChIP-Seq_MESCs_Mouse0.92846218
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.92781064
109POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.92378169
110PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.90357341
111RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.89963950
112HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.89661348
113ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.89578582
114CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89489365
115SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.86728443
116HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.86235996
117FOXP1_21924763_ChIP-Seq_HESCs_Human0.85960844
118WT1_19549856_ChIP-ChIP_CCG9911_Human0.85687940
119PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.84645722
120ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.83386270
121OCT4_18692474_ChIP-Seq_MEFs_Mouse0.81795096
122GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.81457886
123NOTCH1_21737748_ChIP-Seq_TLL_Human0.80010630
124TCF3_18692474_ChIP-Seq_MEFs_Mouse0.79442154
125FLI1_27457419_Chip-Seq_LIVER_Mouse0.78913659
126MYC_18940864_ChIP-ChIP_HL60_Human0.77619696
127MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.77184778
128GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.76502949
129HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.76153838
130* REST_19997604_ChIP-ChIP_NEURONS_Mouse0.74978301
131CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.74474393

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.70438316
2MP0004957_abnormal_blastocyst_morpholog4.40476721
3MP0003111_abnormal_nucleus_morphology4.07819396
4MP0010094_abnormal_chromosome_stability3.84445166
5MP0003077_abnormal_cell_cycle3.53938746
6MP0010352_gastrointestinal_tract_polyps3.44441115
7MP0008057_abnormal_DNA_replication3.26891749
8MP0003705_abnormal_hypodermis_morpholog3.02146246
9MP0003123_paternal_imprinting2.90631668
10MP0001730_embryonic_growth_arrest2.87392317
11MP0001529_abnormal_vocalization2.53232189
12MP0008007_abnormal_cellular_replicative2.50185569
13MP0008932_abnormal_embryonic_tissue2.36067130
14MP0000350_abnormal_cell_proliferation2.30730639
15MP0008789_abnormal_olfactory_epithelium2.29648058
16MP0002102_abnormal_ear_morphology2.29073099
17MP0000537_abnormal_urethra_morphology2.27288525
18MP0010307_abnormal_tumor_latency2.20538328
19MP0008058_abnormal_DNA_repair2.14034927
20MP0001697_abnormal_embryo_size2.09490966
21MP0001672_abnormal_embryogenesis/_devel2.02348239
22MP0005380_embryogenesis_phenotype2.02348239
23MP0005394_taste/olfaction_phenotype2.00967542
24MP0005499_abnormal_olfactory_system2.00967542
25MP0009697_abnormal_copulation1.96819854
26* MP0002080_prenatal_lethality1.89673398
27MP0003984_embryonic_growth_retardation1.87105171
28MP0004197_abnormal_fetal_growth/weight/1.85782712
29MP0006054_spinal_hemorrhage1.85301437
30MP0002088_abnormal_embryonic_growth/wei1.84806445
31* MP0002084_abnormal_developmental_patter1.80816988
32MP0003806_abnormal_nucleotide_metabolis1.76438609
33MP0005076_abnormal_cell_differentiation1.76416892
34* MP0002085_abnormal_embryonic_tissue1.73265179
35MP0002396_abnormal_hematopoietic_system1.71342316
36MP0002086_abnormal_extraembryonic_tissu1.67396664
37MP0003221_abnormal_cardiomyocyte_apopto1.67029396
38MP0003567_abnormal_fetal_cardiomyocyte1.61733086
39MP0003941_abnormal_skin_development1.57091382
40MP0006072_abnormal_retinal_apoptosis1.50643294
41MP0010030_abnormal_orbit_morphology1.50516835
42MP0009053_abnormal_anal_canal1.50239924
43MP0009672_abnormal_birth_weight1.46445846
44MP0004808_abnormal_hematopoietic_stem1.43697107
45MP0002233_abnormal_nose_morphology1.39846627
46MP0000490_abnormal_crypts_of1.39405823
47MP0000049_abnormal_middle_ear1.37641255
48MP0001984_abnormal_olfaction1.36802984
49MP0000358_abnormal_cell_content/1.34358684
50MP0010234_abnormal_vibrissa_follicle1.32573572
51MP0003880_abnormal_central_pattern1.32292877
52MP0003186_abnormal_redox_activity1.30778914
53MP0004233_abnormal_muscle_weight1.28712135
54MP0003122_maternal_imprinting1.27961371
55MP0000313_abnormal_cell_death1.27777968
56MP0001849_ear_inflammation1.26308128
57MP0000733_abnormal_muscle_development1.24784776
58MP0002019_abnormal_tumor_incidence1.24421366
59MP0003119_abnormal_digestive_system1.22510060
60MP0006292_abnormal_olfactory_placode1.22429011
61MP0002751_abnormal_autonomic_nervous1.19997734
62MP0003786_premature_aging1.16166312
63MP0000647_abnormal_sebaceous_gland1.15924118
64MP0005187_abnormal_penis_morphology1.15303134
65MP0003755_abnormal_palate_morphology1.14365202
66MP0002938_white_spotting1.14226170
67MP0001293_anophthalmia1.10938926
68MP0008877_abnormal_DNA_methylation1.10196268
69MP0001286_abnormal_eye_development1.09043157
70MP0003890_abnormal_embryonic-extraembry1.08844323
71MP0000428_abnormal_craniofacial_morphol1.08747045
72MP0006276_abnormal_autonomic_nervous1.07601692
73MP0002877_abnormal_melanocyte_morpholog1.06627213
74MP0000747_muscle_weakness1.05527775
75MP0004270_analgesia1.02677058
76MP0009840_abnormal_foam_cell1.02473249
77MP0000778_abnormal_nervous_system1.02036062
78MP0001299_abnormal_eye_distance/1.01243414
79MP0000750_abnormal_muscle_regeneration0.99608110
80MP0002269_muscular_atrophy0.99147810
81MP0003718_maternal_effect0.97906863
82MP0003121_genomic_imprinting0.96639820
83MP0009703_decreased_birth_body0.96468502
84MP0003566_abnormal_cell_adhesion0.96397998
85MP0002090_abnormal_vision0.95896382
86MP0004185_abnormal_adipocyte_glucose0.94179621
87MP0005384_cellular_phenotype0.92855885
88MP0005253_abnormal_eye_physiology0.92365755
89MP0001188_hyperpigmentation0.91783338
90MP0002092_abnormal_eye_morphology0.89914388
91MP0001915_intracranial_hemorrhage0.89813704
92MP0005621_abnormal_cell_physiology0.89454514
93MP0001145_abnormal_male_reproductive0.88339938
94MP0002653_abnormal_ependyma_morphology0.88169788
95MP0003115_abnormal_respiratory_system0.87530496
96MP0002111_abnormal_tail_morphology0.86932671
97MP0002736_abnormal_nociception_after0.86726928
98MP0005023_abnormal_wound_healing0.85474304
99MP0000762_abnormal_tongue_morphology0.84982818
100MP0004272_abnormal_basement_membrane0.84966726
101MP0002210_abnormal_sex_determination0.83903144
102MP0004084_abnormal_cardiac_muscle0.83847947
103MP0001545_abnormal_hematopoietic_system0.82662697
104MP0005397_hematopoietic_system_phenotyp0.82662697
105MP0004133_heterotaxia0.81970676
106MP0009333_abnormal_splenocyte_physiolog0.80628679
107MP0008770_decreased_survivor_rate0.80201197
108MP0003698_abnormal_male_reproductive0.80123195
109MP0004215_abnormal_myocardial_fiber0.78733403
110MP0001929_abnormal_gametogenesis0.77451506
111MP0002184_abnormal_innervation0.77321826
112MP0005391_vision/eye_phenotype0.76609475
113MP0000703_abnormal_thymus_morphology0.75932508
114MP0003385_abnormal_body_wall0.75752070
115MP0000579_abnormal_nail_morphology0.75037351
116MP0005623_abnormal_meninges_morphology0.74971042
117MP0005501_abnormal_skin_physiology0.74773107
118MP0000631_abnormal_neuroendocrine_gland0.74315636
119MP0000858_altered_metastatic_potential0.73930216
120MP0008995_early_reproductive_senescence0.73572863
121MP0001177_atelectasis0.73461468
122MP0002177_abnormal_outer_ear0.71433605
123MP0003315_abnormal_perineum_morphology0.71118738
124MP0003283_abnormal_digestive_organ0.70433064
125MP0003935_abnormal_craniofacial_develop0.69951785
126MP0004811_abnormal_neuron_physiology0.69917384
127MP0003937_abnormal_limbs/digits/tail_de0.69722563
128MP0002282_abnormal_trachea_morphology0.69602805
129MP0000653_abnormal_sex_gland0.68667149
130MP0000477_abnormal_intestine_morphology0.68531613
131MP0005248_abnormal_Harderian_gland0.67498804
132MP0002234_abnormal_pharynx_morphology0.66001940
133MP0005367_renal/urinary_system_phenotyp0.65357017
134MP0000516_abnormal_urinary_system0.65357017
135MP0002089_abnormal_postnatal_growth/wei0.64764095
136MP0000598_abnormal_liver_morphology0.63366975
137MP0002697_abnormal_eye_size0.62444321
138MP0005266_abnormal_metabolism0.62039615
139MP0005666_abnormal_adipose_tissue0.61874877
140MP0004087_abnormal_muscle_fiber0.59906567
141MP0006035_abnormal_mitochondrial_morpho0.59752931
142MP0010630_abnormal_cardiac_muscle0.59325803
143MP0002160_abnormal_reproductive_system0.58370020
144* MP0000266_abnormal_heart_morphology0.58262603
145MP0001661_extended_life_span0.56376229
146MP0006036_abnormal_mitochondrial_physio0.55596586
147* MP0003861_abnormal_nervous_system0.54741748
148MP0000377_abnormal_hair_follicle0.53438944

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)3.92660872
2Increased serum pyruvate (HP:0003542)3.75043053
3Abnormality of glycolysis (HP:0004366)3.72606517
4Colon cancer (HP:0003003)3.67475660
5Selective tooth agenesis (HP:0001592)3.59031234
6Ependymoma (HP:0002888)3.53028773
7Pelvic girdle muscle weakness (HP:0003749)3.41033412
8Abnormality of the anterior horn cell (HP:0006802)3.31445814
9Degeneration of anterior horn cells (HP:0002398)3.31445814
10Abnormality of the labia minora (HP:0012880)3.25282186
11Multiple enchondromatosis (HP:0005701)3.23591281
12Shoulder girdle muscle weakness (HP:0003547)3.21992000
13Oral leukoplakia (HP:0002745)3.19005025
14Abnormality of the hip-girdle musculature (HP:0001445)2.93090413
15Abnormality of the musculature of the pelvis (HP:0001469)2.93090413
16Breast hypoplasia (HP:0003187)2.86086912
17Angiofibromas (HP:0010615)2.82809524
18Adenoma sebaceum (HP:0009720)2.82809524
19Acute necrotizing encephalopathy (HP:0006965)2.80782175
20Protrusio acetabuli (HP:0003179)2.79981345
21Cerebral hypomyelination (HP:0006808)2.68904532
22Atrophy/Degeneration involving motor neurons (HP:0007373)2.68166652
23Cortical dysplasia (HP:0002539)2.67831066
24Microretrognathia (HP:0000308)2.67819165
25Acute encephalopathy (HP:0006846)2.65620077
26Abnormal mitochondria in muscle tissue (HP:0008316)2.59969070
27Progressive muscle weakness (HP:0003323)2.58394608
28Abnormality of cells of the erythroid lineage (HP:0012130)2.56190800
29Neoplasm of the pancreas (HP:0002894)2.56022553
30Trismus (HP:0000211)2.55307126
31Proximal placement of thumb (HP:0009623)2.51341254
32Ankle contracture (HP:0006466)2.51004939
33Abnormality of the calcaneus (HP:0008364)2.48100578
34Microvesicular hepatic steatosis (HP:0001414)2.45512031
35Abnormality of the astrocytes (HP:0100707)2.45472443
36Astrocytoma (HP:0009592)2.45472443
37Calcaneovalgus deformity (HP:0001848)2.44375292
38Abnormal lung lobation (HP:0002101)2.44181797
39Carpal bone hypoplasia (HP:0001498)2.41284829
40Deviation of the thumb (HP:0009603)2.40894465
41Spastic diplegia (HP:0001264)2.40766448
42Basal cell carcinoma (HP:0002671)2.39824669
43Abnormal number of erythroid precursors (HP:0012131)2.37770360
44Deformed tarsal bones (HP:0008119)2.36574140
45Rough bone trabeculation (HP:0100670)2.36158640
46Medulloblastoma (HP:0002885)2.34582551
47Biliary tract neoplasm (HP:0100574)2.32920278
48Increased CSF lactate (HP:0002490)2.30671497
49Rhabdomyosarcoma (HP:0002859)2.30404202
50Progressive macrocephaly (HP:0004481)2.27693428
51Aplasia/Hypoplasia of the patella (HP:0006498)2.25762213
52Patellar aplasia (HP:0006443)2.25100867
53Increased nuchal translucency (HP:0010880)2.24510503
54Cerebral edema (HP:0002181)2.23995074
55Glossoptosis (HP:0000162)2.22973693
56Hyperglycinemia (HP:0002154)2.22660661
57Impulsivity (HP:0100710)2.21294650
58Difficulty climbing stairs (HP:0003551)2.20898669
59Increased hepatocellular lipid droplets (HP:0006565)2.20656696
60Slender long bone (HP:0003100)2.18453451
61Missing ribs (HP:0000921)2.17031669
62Overlapping toe (HP:0001845)2.16643572
63Abnormal protein N-linked glycosylation (HP:0012347)2.15585079
64Abnormal protein glycosylation (HP:0012346)2.15585079
65Abnormal glycosylation (HP:0012345)2.15585079
66Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.15585079
67Atresia of the external auditory canal (HP:0000413)2.14838356
68Cutaneous melanoma (HP:0012056)2.14607062
69Genu recurvatum (HP:0002816)2.14222936
70Increased serum lactate (HP:0002151)2.13905054
71Reticulocytopenia (HP:0001896)2.11554997
72Mitochondrial inheritance (HP:0001427)2.11271435
73Type I transferrin isoform profile (HP:0003642)2.11172134
74Abnormality of methionine metabolism (HP:0010901)2.09400224
75Neoplasm of the rectum (HP:0100743)2.08203632
76Hepatocellular necrosis (HP:0001404)2.07051560
77Achilles tendon contracture (HP:0001771)2.05835624
78Exercise-induced muscle cramps (HP:0003710)2.05548808
79Amyotrophic lateral sclerosis (HP:0007354)2.05376483
80Abnormality of serum amino acid levels (HP:0003112)2.05211378
81Glioma (HP:0009733)2.04932535
82Hepatic necrosis (HP:0002605)2.04761470
83Meckel diverticulum (HP:0002245)2.02946842
84Prominent nose (HP:0000448)2.02291863
85Cholecystitis (HP:0001082)2.00756878
86Abnormal gallbladder physiology (HP:0012438)2.00756878
87Intestinal polyp (HP:0005266)1.99604736
88Intestinal polyposis (HP:0200008)1.99436731
89Squamous cell carcinoma (HP:0002860)1.98789060
90Abnormality of alanine metabolism (HP:0010916)1.98640105
91Hyperalaninemia (HP:0003348)1.98640105
92Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.98640105
93Increased density of long bones (HP:0006392)1.97527560
94Lipid accumulation in hepatocytes (HP:0006561)1.97424437
95Rhabdomyolysis (HP:0003201)1.95208509
96Posterior subcapsular cataract (HP:0007787)1.94248235
97Facial hemangioma (HP:0000329)1.93469109
98Congenital primary aphakia (HP:0007707)1.93295102
99Abnormality of the ileum (HP:0001549)1.92875661
100Postnatal microcephaly (HP:0005484)1.91922741
101Abnormality of the lower motor neuron (HP:0002366)1.91449043
102Abnormality of the Achilles tendon (HP:0005109)1.90586394
103Hypoplastic pelvis (HP:0008839)1.90580664
104Neoplasm of the colon (HP:0100273)1.90418283
105Poor suck (HP:0002033)1.90370480
106Bifid tongue (HP:0010297)1.89481747
107Limb-girdle muscle weakness (HP:0003325)1.88464387
108Fibroma (HP:0010614)1.88037403
109Upper limb muscle weakness (HP:0003484)1.87309869
110Premature ovarian failure (HP:0008209)1.87234993
111Nephrogenic diabetes insipidus (HP:0009806)1.85849043
112Secondary amenorrhea (HP:0000869)1.85035380
113Neoplasm of the small intestine (HP:0100833)1.84791039
114Decreased activity of mitochondrial respiratory chain (HP:0008972)1.83806051
115Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.83806051
116Lactic acidosis (HP:0003128)1.83055094
117Gait imbalance (HP:0002141)1.82977377
118Fibrous tissue neoplasm (HP:0012316)1.82742095
119Horseshoe kidney (HP:0000085)1.81473685
120Aplastic anemia (HP:0001915)1.81384139
121Renal duplication (HP:0000075)1.81352204
122Ovarian neoplasm (HP:0100615)1.80918644
123Bowel diverticulosis (HP:0005222)1.80300427
124Chromsome breakage (HP:0040012)1.80214272
125High pitched voice (HP:0001620)1.80140948
126Volvulus (HP:0002580)1.79851380
127Rectal prolapse (HP:0002035)1.79678432
128Short 4th metacarpal (HP:0010044)1.79217382
129Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.79217382
130Hyperacusis (HP:0010780)1.79070018
131Abnormality of the motor neurons (HP:0002450)1.78650687
132Abnormal neuron morphology (HP:0012757)1.78650687
133Megaloblastic anemia (HP:0001889)1.78634721
134Medial flaring of the eyebrow (HP:0010747)1.78258576
135Hypoplasia of the pons (HP:0012110)1.78188615
136Shallow orbits (HP:0000586)1.78110652
137Methylmalonic acidemia (HP:0002912)1.77411385
138Chromosomal breakage induced by crosslinking agents (HP:0003221)1.76330880
139Neoplasm of striated muscle (HP:0009728)1.75886091
140Hypoglycemic coma (HP:0001325)1.75243532
141Back pain (HP:0003418)1.74444213
142Cafe-au-lait spot (HP:0000957)1.74432265
143Freckling (HP:0001480)1.74088855
144Short palpebral fissure (HP:0012745)1.73373698
145Gonadotropin excess (HP:0000837)1.72372041
146Stenosis of the external auditory canal (HP:0000402)1.71778847
147CNS hypomyelination (HP:0003429)1.71231893
148Abnormality of glycine metabolism (HP:0010895)1.70277812
149Abnormality of serine family amino acid metabolism (HP:0010894)1.70277812
150Small intestinal stenosis (HP:0012848)1.69979826
151Duodenal stenosis (HP:0100867)1.69979826
152Exercise intolerance (HP:0003546)1.69708705
153Personality changes (HP:0000751)1.69679697
154Gastrointestinal carcinoma (HP:0002672)1.69348146
155Malignant gastrointestinal tract tumors (HP:0006749)1.69348146
156Intestinal atresia (HP:0011100)1.68777665
157Aplasia/Hypoplasia of the uvula (HP:0010293)1.66383182
158Nephroblastoma (Wilms tumor) (HP:0002667)1.64880989
159Abnormality of the metopic suture (HP:0005556)1.64358075
160Prominent metopic ridge (HP:0005487)1.64162260
161Preaxial hand polydactyly (HP:0001177)1.64054702
162Facial cleft (HP:0002006)1.61780825
163Rimmed vacuoles (HP:0003805)1.61205750
164Abnormality of chromosome stability (HP:0003220)1.61058414
165Abnormality of aspartate family amino acid metabolism (HP:0010899)1.60445076
166Embryonal renal neoplasm (HP:0011794)1.60256506
167Broad foot (HP:0001769)1.60080250
168Abnormality of the duodenum (HP:0002246)1.59983611
169Central scotoma (HP:0000603)1.59607993
170Supernumerary spleens (HP:0009799)1.58283340
171Short tibia (HP:0005736)1.57531982
172Vaginal atresia (HP:0000148)1.57283982
173Oligodactyly (hands) (HP:0001180)1.56735857
174Genital tract atresia (HP:0001827)1.56259574
175Abnormality of the preputium (HP:0100587)1.56237916
176Delayed gross motor development (HP:0002194)1.53402106
177Neoplasm of the adrenal gland (HP:0100631)1.52132704

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE13.96805728
2CDC73.81021499
3BUB13.69050340
4TRIM283.25454104
5NEK12.94069580
6NEK22.91975359
7SCYL22.81930682
8BCR2.65624672
9TRIB32.60971485
10PBK2.46680155
11EIF2AK12.44991803
12PKN22.41074266
13VRK22.32993452
14EEF2K2.14584109
15RPS6KA42.01531648
16TESK21.98077616
17TTK1.96333923
18BRSK21.92977067
19DYRK31.92513218
20ACVR1B1.92384605
21MST41.74870351
22PASK1.69859967
23LATS21.68315110
24ERBB31.67013736
25WNK31.64566602
26CSNK1G31.64047825
27MAP3K101.63086954
28MAP3K81.62427488
29EPHA21.61505717
30PLK11.59841120
31CSNK1G11.59759735
32TSSK61.58117608
33MAP4K21.54337454
34RPS6KB21.48308414
35PDK31.47967152
36PDK41.47967152
37SRPK11.47820410
38PLK21.45528533
39NME21.43765911
40CSNK1A1L1.42974136
41CSNK1G21.40306601
42BRSK11.40086426
43EIF2AK31.38895926
44TESK11.38683897
45PAK41.38621061
46STK101.38319545
47CDK41.34311973
48AURKB1.32222446
49ZAK1.32132614
50PLK31.31901816
51MAP2K71.30769234
52LRRK21.29062399
53MAP3K41.24824116
54ATR1.24021660
55ALK1.21893185
56CASK1.15738262
57SIK31.14625915
58AURKA1.11148010
59CDK71.10019064
60CHEK21.08341393
61CHEK11.05260878
62MKNK11.04239227
63TGFBR11.03899885
64DYRK21.03041739
65PLK41.02743350
66CDK121.02715166
67TAF11.01714992
68NME11.00579715
69FLT30.99245374
70NUAK10.97143367
71TTN0.93838122
72STK30.91146235
73PDGFRA0.91134346
74KSR10.90789885
75CDK190.84852240
76MAP3K110.82002733
77BRD40.80792511
78PTK60.79880081
79CDK60.79507102
80PAK20.79121300
81LATS10.77624071
82STK160.75652302
83KSR20.74473700
84MET0.74082674
85ERBB40.73915262
86TNIK0.73500577
87MAPKAPK30.73425165
88EIF2AK20.73413499
89CDK20.71851747
90MTOR0.70778509
91KDR0.69864800
92MINK10.69465260
93LIMK10.69062473
94PAK10.69024243
95RAF10.66757324
96CDK180.66229480
97EPHA40.65176125
98ILK0.62548133
99FGFR10.62128874
100MAP2K30.62082214
101BMPR1B0.61795497
102DAPK10.61610108
103ATM0.60358752
104MAP3K120.59014833
105TAOK10.58287015
106MELK0.58210699
107TLK10.58106515
108BCKDK0.57801771
109ARAF0.57425121
110VRK10.56663702
111MARK10.55732570
112CCNB10.55281398
113CDK150.54878479
114CSNK2A20.52569061
115CSNK1E0.51322312
116AKT20.50551263
117PNCK0.50498616
118PINK10.50213862
119TAOK20.49423791
120CDK10.48809739
121PDK20.48744331
122MAPKAPK50.47068956
123CDK90.44253709
124ERN10.43400542
125RIPK10.42810590
126PIM20.41752677
127CDK30.41731306
128PIM10.40582989
129NEK90.39785476
130CDK140.39578093
131CSNK2A10.39356218
132PRKCI0.36872629
133MKNK20.35777885
134PRKCG0.35103348
135MARK30.33154867
136BRAF0.30899631
137STK38L0.30391900
138STK40.30329573
139MAPK110.29345232
140ICK0.27647776
141PRKDC0.27510649
142CDK11A0.27208433

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.41481631
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.48093043
3* RNA transport_Homo sapiens_hsa030133.47810515
4Mismatch repair_Homo sapiens_hsa034303.34695051
5Spliceosome_Homo sapiens_hsa030403.07177709
6Protein export_Homo sapiens_hsa030602.99772900
7Cell cycle_Homo sapiens_hsa041102.98658157
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.93406104
9Proteasome_Homo sapiens_hsa030502.78661498
10One carbon pool by folate_Homo sapiens_hsa006702.74459417
11RNA polymerase_Homo sapiens_hsa030202.52809789
12Base excision repair_Homo sapiens_hsa034102.38734557
13Nucleotide excision repair_Homo sapiens_hsa034202.27689843
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.19038002
15Pyrimidine metabolism_Homo sapiens_hsa002402.13243689
16Ribosome_Homo sapiens_hsa030102.12963664
17Steroid biosynthesis_Homo sapiens_hsa001001.89263178
18Homologous recombination_Homo sapiens_hsa034401.81139869
19mRNA surveillance pathway_Homo sapiens_hsa030151.79993228
20Selenocompound metabolism_Homo sapiens_hsa004501.78704538
21Fatty acid elongation_Homo sapiens_hsa000621.78389413
22Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.76081010
23Biosynthesis of amino acids_Homo sapiens_hsa012301.73385993
24Oxidative phosphorylation_Homo sapiens_hsa001901.72507548
25Parkinsons disease_Homo sapiens_hsa050121.72276726
26p53 signaling pathway_Homo sapiens_hsa041151.67857544
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.55620726
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.53547122
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.51902691
30Oocyte meiosis_Homo sapiens_hsa041141.50248053
31Carbon metabolism_Homo sapiens_hsa012001.40717621
32Pentose phosphate pathway_Homo sapiens_hsa000301.39068801
33RNA degradation_Homo sapiens_hsa030181.38824236
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.36748327
35Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.33555688
36Vitamin B6 metabolism_Homo sapiens_hsa007501.32318281
37Huntingtons disease_Homo sapiens_hsa050161.27940239
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.27133034
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.26279489
40Non-homologous end-joining_Homo sapiens_hsa034501.25359518
41Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.22324481
42Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.22031369
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.19585664
44Viral carcinogenesis_Homo sapiens_hsa052031.12321534
45Basal transcription factors_Homo sapiens_hsa030221.10457800
46Epstein-Barr virus infection_Homo sapiens_hsa051691.10243695
47Fanconi anemia pathway_Homo sapiens_hsa034601.09005466
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08574616
49Sulfur relay system_Homo sapiens_hsa041221.08018433
50Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.04088971
51Central carbon metabolism in cancer_Homo sapiens_hsa052301.03199541
52Thyroid cancer_Homo sapiens_hsa052161.00593725
53Systemic lupus erythematosus_Homo sapiens_hsa053220.98547727
54Purine metabolism_Homo sapiens_hsa002300.95315718
55Folate biosynthesis_Homo sapiens_hsa007900.94241962
56Alzheimers disease_Homo sapiens_hsa050100.94131071
57Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.92591343
58Drug metabolism - other enzymes_Homo sapiens_hsa009830.89109725
59Bladder cancer_Homo sapiens_hsa052190.86868384
60mTOR signaling pathway_Homo sapiens_hsa041500.85328783
61Small cell lung cancer_Homo sapiens_hsa052220.84761291
62HTLV-I infection_Homo sapiens_hsa051660.82153146
63Antigen processing and presentation_Homo sapiens_hsa046120.81985529
64Fatty acid metabolism_Homo sapiens_hsa012120.79740970
65MicroRNAs in cancer_Homo sapiens_hsa052060.79234235
66Chronic myeloid leukemia_Homo sapiens_hsa052200.78982746
67Hippo signaling pathway_Homo sapiens_hsa043900.78962146
68Cyanoamino acid metabolism_Homo sapiens_hsa004600.78265673
69Colorectal cancer_Homo sapiens_hsa052100.71378122
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68654551
71Vibrio cholerae infection_Homo sapiens_hsa051100.68230800
72Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.67905417
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.67632320
74N-Glycan biosynthesis_Homo sapiens_hsa005100.65225181
75Metabolic pathways_Homo sapiens_hsa011000.65131364
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64779874
77Butanoate metabolism_Homo sapiens_hsa006500.64367867
78Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.63753955
79Nitrogen metabolism_Homo sapiens_hsa009100.61738725
80Legionellosis_Homo sapiens_hsa051340.53740346
81Regulation of autophagy_Homo sapiens_hsa041400.53171993
82Sulfur metabolism_Homo sapiens_hsa009200.52979457
83Pyruvate metabolism_Homo sapiens_hsa006200.52606320
84beta-Alanine metabolism_Homo sapiens_hsa004100.49242764
85AMPK signaling pathway_Homo sapiens_hsa041520.47315779
86Non-small cell lung cancer_Homo sapiens_hsa052230.47064219
87Herpes simplex infection_Homo sapiens_hsa051680.46729835
88Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46645531
89Peroxisome_Homo sapiens_hsa041460.46123674
90Glutathione metabolism_Homo sapiens_hsa004800.45232360
91Cardiac muscle contraction_Homo sapiens_hsa042600.44911017
92Phototransduction_Homo sapiens_hsa047440.44553761
93Shigellosis_Homo sapiens_hsa051310.43036802
94HIF-1 signaling pathway_Homo sapiens_hsa040660.42762442
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.41558211
96Alcoholism_Homo sapiens_hsa050340.41298821
97Proteoglycans in cancer_Homo sapiens_hsa052050.41265048
98TGF-beta signaling pathway_Homo sapiens_hsa043500.40992916
99Endometrial cancer_Homo sapiens_hsa052130.40674315
100Fructose and mannose metabolism_Homo sapiens_hsa000510.37917820
101Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37132736
102VEGF signaling pathway_Homo sapiens_hsa043700.36920486
103Wnt signaling pathway_Homo sapiens_hsa043100.36372050
104Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.36008075
105Viral myocarditis_Homo sapiens_hsa054160.35265446
106Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.35086532
107Hepatitis B_Homo sapiens_hsa051610.34791836
108Insulin signaling pathway_Homo sapiens_hsa049100.34210222
109Synaptic vesicle cycle_Homo sapiens_hsa047210.34174892
110Adherens junction_Homo sapiens_hsa045200.32534265
111Apoptosis_Homo sapiens_hsa042100.32088061
112Glioma_Homo sapiens_hsa052140.30189449
113Circadian rhythm_Homo sapiens_hsa047100.29822164
114Galactose metabolism_Homo sapiens_hsa000520.29745572
115Glucagon signaling pathway_Homo sapiens_hsa049220.29526453
116Basal cell carcinoma_Homo sapiens_hsa052170.29177086
117Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29043836
118Collecting duct acid secretion_Homo sapiens_hsa049660.28932902
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.27215171
120Neurotrophin signaling pathway_Homo sapiens_hsa047220.26872004
121Pancreatic cancer_Homo sapiens_hsa052120.26602359
122Tight junction_Homo sapiens_hsa045300.25860422
123Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.25275351
124Acute myeloid leukemia_Homo sapiens_hsa052210.24346613
125Pentose and glucuronate interconversions_Homo sapiens_hsa000400.23319496
126Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.23092854
127Prostate cancer_Homo sapiens_hsa052150.23048660
128Nicotine addiction_Homo sapiens_hsa050330.22367182
129Arginine biosynthesis_Homo sapiens_hsa002200.22130322
130Renal cell carcinoma_Homo sapiens_hsa052110.21991903
131Phenylalanine metabolism_Homo sapiens_hsa003600.20272028
132GABAergic synapse_Homo sapiens_hsa047270.19382106
133Propanoate metabolism_Homo sapiens_hsa006400.19189108
134Longevity regulating pathway - mammal_Homo sapiens_hsa042110.19058310
135Hedgehog signaling pathway_Homo sapiens_hsa043400.19012237
136Fatty acid degradation_Homo sapiens_hsa000710.18693664
137Arginine and proline metabolism_Homo sapiens_hsa003300.17457982
138Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.16951993
139Lysine degradation_Homo sapiens_hsa003100.16655445

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