

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | urinary tract smooth muscle contraction (GO:0014848) | 6.04550017 |
| 2 | regulation of female receptivity (GO:0045924) | 5.62422841 |
| 3 | tachykinin receptor signaling pathway (GO:0007217) | 5.49158581 |
| 4 | vocalization behavior (GO:0071625) | 5.03548207 |
| 5 | synaptic vesicle maturation (GO:0016188) | 4.97264310 |
| 6 | glutamate secretion (GO:0014047) | 4.86496919 |
| 7 | female mating behavior (GO:0060180) | 4.69052077 |
| 8 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 4.64860940 |
| 9 | positive regulation of vascular permeability (GO:0043117) | 4.63377538 |
| 10 | maintenance of gastrointestinal epithelium (GO:0030277) | 4.53158743 |
| 11 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.52147811 |
| 12 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.51982468 |
| 13 | synaptic vesicle exocytosis (GO:0016079) | 4.40120939 |
| 14 | positive regulation of action potential (GO:0045760) | 4.30307475 |
| 15 | synaptic transmission, dopaminergic (GO:0001963) | 4.18501772 |
| 16 | positive regulation of synapse maturation (GO:0090129) | 4.18368802 |
| 17 | drinking behavior (GO:0042756) | 4.16686287 |
| 18 | neuronal action potential propagation (GO:0019227) | 4.15967768 |
| 19 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.14503436 |
| 20 | positive regulation of digestive system process (GO:0060456) | 4.05684032 |
| 21 | behavioral response to pain (GO:0048266) | 3.88923785 |
| 22 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.81876114 |
| 23 | membrane depolarization during action potential (GO:0086010) | 3.81608901 |
| 24 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.80444118 |
| 25 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.78904832 |
| 26 | regulation of synapse maturation (GO:0090128) | 3.78333783 |
| 27 | cerebellar granule cell differentiation (GO:0021707) | 3.76650853 |
| 28 | regulation of ARF protein signal transduction (GO:0032012) | 3.75498036 |
| 29 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.72393796 |
| 30 | regulation of G0 to G1 transition (GO:0070316) | 3.66602097 |
| 31 | dendritic spine morphogenesis (GO:0060997) | 3.65389276 |
| 32 | regulation of uterine smooth muscle contraction (GO:0070472) | 3.64472611 |
| 33 | synaptic vesicle endocytosis (GO:0048488) | 3.62542360 |
| 34 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.61575938 |
| 35 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.55836935 |
| 36 | dicarboxylic acid biosynthetic process (GO:0043650) | 3.48901919 |
| 37 | response to auditory stimulus (GO:0010996) | 3.45646549 |
| 38 | regulation of ARF GTPase activity (GO:0032312) | 3.44936436 |
| 39 | regulation of action potential (GO:0098900) | 3.41851072 |
| 40 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.41523192 |
| 41 | neurotransmitter secretion (GO:0007269) | 3.38141467 |
| 42 | inositol metabolic process (GO:0006020) | 3.37265117 |
| 43 | auditory receptor cell stereocilium organization (GO:0060088) | 3.34599067 |
| 44 | long term synaptic depression (GO:0060292) | 3.34394344 |
| 45 | regulation of synaptic transmission, GABAergic (GO:0032228) | 3.29477957 |
| 46 | regulation of synaptic vesicle transport (GO:1902803) | 3.27661518 |
| 47 | neuron-neuron synaptic transmission (GO:0007270) | 3.26123057 |
| 48 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.23301139 |
| 49 | epithelial structure maintenance (GO:0010669) | 3.21484038 |
| 50 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.18735720 |
| 51 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.18466522 |
| 52 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.18403535 |
| 53 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.16234849 |
| 54 | glutamate receptor signaling pathway (GO:0007215) | 3.14205835 |
| 55 | snRNA transcription (GO:0009301) | 3.14161991 |
| 56 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.11582361 |
| 57 | L-amino acid import (GO:0043092) | 3.10027817 |
| 58 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 3.08505461 |
| 59 | neuronal ion channel clustering (GO:0045161) | 3.08453392 |
| 60 | dendritic spine organization (GO:0097061) | 3.02634543 |
| 61 | long-term memory (GO:0007616) | 3.00513135 |
| 62 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.99289301 |
| 63 | sodium ion export (GO:0071436) | 2.96597512 |
| 64 | cellular potassium ion homeostasis (GO:0030007) | 2.88832540 |
| 65 | synaptic transmission, glutamatergic (GO:0035249) | 2.86976006 |
| 66 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.85828812 |
| 67 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.83215131 |
| 68 | aggressive behavior (GO:0002118) | 2.82272340 |
| 69 | phospholipid scrambling (GO:0017121) | 2.77503619 |
| 70 | regulation of synaptic plasticity (GO:0048167) | 2.77087319 |
| 71 | membrane depolarization (GO:0051899) | 2.76919229 |
| 72 | establishment of skin barrier (GO:0061436) | 2.74861477 |
| 73 | cardiac conduction (GO:0061337) | 2.72923531 |
| 74 | regulation of neurotransmitter secretion (GO:0046928) | 2.72855111 |
| 75 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.72174144 |
| 76 | locomotory exploration behavior (GO:0035641) | 2.70006620 |
| 77 | mannose metabolic process (GO:0006013) | 2.68455443 |
| 78 | regulation of alkaline phosphatase activity (GO:0010692) | 2.67279439 |
| 79 | adaptation of signaling pathway (GO:0023058) | 2.65550073 |
| 80 | microtubule nucleation (GO:0007020) | 2.64965342 |
| 81 | response to pheromone (GO:0019236) | 2.64538984 |
| 82 | regulation of synapse structural plasticity (GO:0051823) | 2.64490896 |
| 83 | neurotransmitter transport (GO:0006836) | 2.63204918 |
| 84 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 2.59829421 |
| 85 | UMP metabolic process (GO:0046049) | 2.59829421 |
| 86 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 2.59829421 |
| 87 | UMP biosynthetic process (GO:0006222) | 2.59829421 |
| 88 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.59232518 |
| 89 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.58743446 |
| 90 | positive regulation of membrane potential (GO:0045838) | 2.58199010 |
| 91 | nephron tubule morphogenesis (GO:0072078) | 2.58126129 |
| 92 | nephron epithelium morphogenesis (GO:0072088) | 2.58126129 |
| 93 | neuronal action potential (GO:0019228) | 2.55933792 |
| 94 | positive regulation of exocytosis (GO:0045921) | 2.55668434 |
| 95 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.54791627 |
| 96 | cell communication involved in cardiac conduction (GO:0086065) | 2.52988846 |
| 97 | gamma-aminobutyric acid transport (GO:0015812) | 2.52137339 |
| 98 | renal tubule morphogenesis (GO:0061333) | 2.51762953 |
| 99 | negative regulation of digestive system process (GO:0060457) | 2.50367495 |
| 100 | regulation of female gonad development (GO:2000194) | 2.46535296 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DROSHA_22980978_ChIP-Seq_HELA_Human | 4.34160305 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.31988393 |
| 3 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 3.81986982 |
| 4 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.79714758 |
| 5 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.58255817 |
| 6 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.33505244 |
| 7 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.28301758 |
| 8 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.22174088 |
| 9 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 2.13745539 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.04401980 |
| 11 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.03005716 |
| 12 | CTCF_27219007_Chip-Seq_Bcells_Human | 2.00932986 |
| 13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.95097789 |
| 14 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.89271018 |
| 15 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.83003238 |
| 16 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.80602104 |
| 17 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.79131640 |
| 18 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.78250287 |
| 19 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.72273575 |
| 20 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.71988822 |
| 21 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.71315562 |
| 22 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.65413552 |
| 23 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.64872759 |
| 24 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.63110626 |
| 25 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.62936688 |
| 26 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.61698890 |
| 27 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.59890181 |
| 28 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.57614736 |
| 29 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.56668242 |
| 30 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.56532118 |
| 31 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.56068056 |
| 32 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.54204498 |
| 33 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.54150321 |
| 34 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.52821372 |
| 35 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.51806611 |
| 36 | P68_20966046_ChIP-Seq_HELA_Human | 1.50571036 |
| 37 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.44559615 |
| 38 | KDM2B_26808549_Chip-Seq_K562_Human | 1.42140846 |
| 39 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.39871525 |
| 40 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.39124948 |
| 41 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.39124948 |
| 42 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.38924549 |
| 43 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.38902431 |
| 44 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.35514821 |
| 45 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.35341163 |
| 46 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.33613968 |
| 47 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.31594100 |
| 48 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.28643603 |
| 49 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.27277791 |
| 50 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.26819701 |
| 51 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.26391813 |
| 52 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.24387743 |
| 53 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.24371744 |
| 54 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.19586579 |
| 55 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.17830196 |
| 56 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.17754403 |
| 57 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.16206061 |
| 58 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.13694675 |
| 59 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.13553715 |
| 60 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.12189747 |
| 61 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.12043142 |
| 62 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.11189526 |
| 63 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.09903793 |
| 64 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.09479677 |
| 65 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.06998236 |
| 66 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.06111978 |
| 67 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.05782988 |
| 68 | KLF4_19829295_ChIP-Seq_ESCs_Human | 1.05361654 |
| 69 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.05170538 |
| 70 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.05094640 |
| 71 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.04454780 |
| 72 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.03618644 |
| 73 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.01480330 |
| 74 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.00512999 |
| 75 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.97782403 |
| 76 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.97627069 |
| 77 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.97570649 |
| 78 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.96918179 |
| 79 | SA1_27219007_Chip-Seq_Bcells_Human | 0.96762451 |
| 80 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.96543660 |
| 81 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.96467563 |
| 82 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.96035357 |
| 83 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.95219061 |
| 84 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.94749904 |
| 85 | ERA_21632823_ChIP-Seq_H3396_Human | 0.93409778 |
| 86 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.93229838 |
| 87 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.91221545 |
| 88 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.90101363 |
| 89 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.90001915 |
| 90 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.86608807 |
| 91 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.86569013 |
| 92 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.86333930 |
| 93 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.85674110 |
| 94 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.85551567 |
| 95 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82046131 |
| 96 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.80912828 |
| 97 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.79925099 |
| 98 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.79090338 |
| 99 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.78577543 |
| 100 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.76727059 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 4.86662835 |
| 2 | MP0009780_abnormal_chondrocyte_physiolo | 4.01895840 |
| 3 | MP0001968_abnormal_touch/_nociception | 3.68972082 |
| 4 | MP0004270_analgesia | 3.55244300 |
| 5 | MP0002736_abnormal_nociception_after | 3.41700686 |
| 6 | MP0003879_abnormal_hair_cell | 3.27672772 |
| 7 | MP0002735_abnormal_chemical_nociception | 2.98106517 |
| 8 | MP0001188_hyperpigmentation | 2.92039292 |
| 9 | MP0000579_abnormal_nail_morphology | 2.85644997 |
| 10 | MP0005451_abnormal_body_composition | 2.83034971 |
| 11 | MP0002734_abnormal_mechanical_nocicepti | 2.67549059 |
| 12 | MP0003635_abnormal_synaptic_transmissio | 2.61333929 |
| 13 | MP0004043_abnormal_pH_regulation | 2.56667022 |
| 14 | MP0004885_abnormal_endolymph | 2.36614861 |
| 15 | MP0003880_abnormal_central_pattern | 2.35340067 |
| 16 | MP0008260_abnormal_autophagy | 2.32612564 |
| 17 | MP0005423_abnormal_somatic_nervous | 2.30862426 |
| 18 | MP0002822_catalepsy | 2.30064795 |
| 19 | MP0001348_abnormal_lacrimal_gland | 2.23310488 |
| 20 | MP0001986_abnormal_taste_sensitivity | 2.22582336 |
| 21 | MP0009745_abnormal_behavioral_response | 2.22367668 |
| 22 | MP0005670_abnormal_white_adipose | 2.11333970 |
| 23 | MP0003787_abnormal_imprinting | 2.07644259 |
| 24 | MP0004381_abnormal_hair_follicle | 2.00689718 |
| 25 | MP0002572_abnormal_emotion/affect_behav | 1.96144252 |
| 26 | MP0002063_abnormal_learning/memory/cond | 1.95669749 |
| 27 | MP0001661_extended_life_span | 1.91143612 |
| 28 | MP0002064_seizures | 1.90471968 |
| 29 | MP0002272_abnormal_nervous_system | 1.88557453 |
| 30 | MP0004147_increased_porphyrin_level | 1.85124566 |
| 31 | MP0001501_abnormal_sleep_pattern | 1.80872205 |
| 32 | MP0002138_abnormal_hepatobiliary_system | 1.75481325 |
| 33 | MP0001486_abnormal_startle_reflex | 1.74938339 |
| 34 | MP0008569_lethality_at_weaning | 1.67326755 |
| 35 | MP0003136_yellow_coat_color | 1.65735829 |
| 36 | MP0008872_abnormal_physiological_respon | 1.61904409 |
| 37 | MP0003123_paternal_imprinting | 1.53244509 |
| 38 | MP0009046_muscle_twitch | 1.52251953 |
| 39 | MP0005551_abnormal_eye_electrophysiolog | 1.51259820 |
| 40 | MP0001529_abnormal_vocalization | 1.40722310 |
| 41 | MP0002277_abnormal_respiratory_mucosa | 1.34557822 |
| 42 | MP0002098_abnormal_vibrissa_morphology | 1.33767140 |
| 43 | MP0001970_abnormal_pain_threshold | 1.30373453 |
| 44 | MP0006292_abnormal_olfactory_placode | 1.30103057 |
| 45 | MP0003122_maternal_imprinting | 1.27016834 |
| 46 | MP0004924_abnormal_behavior | 1.25322982 |
| 47 | MP0005386_behavior/neurological_phenoty | 1.25322982 |
| 48 | MP0004742_abnormal_vestibular_system | 1.24915689 |
| 49 | MP0006276_abnormal_autonomic_nervous | 1.21888746 |
| 50 | MP0002067_abnormal_sensory_capabilities | 1.20636058 |
| 51 | MP0002557_abnormal_social/conspecific_i | 1.20285487 |
| 52 | MP0001502_abnormal_circadian_rhythm | 1.19648636 |
| 53 | MP0000427_abnormal_hair_cycle | 1.18705603 |
| 54 | MP0000383_abnormal_hair_follicle | 1.15438664 |
| 55 | MP0003329_amyloid_beta_deposits | 1.13234652 |
| 56 | MP0005535_abnormal_body_temperature | 1.07850290 |
| 57 | MP0005646_abnormal_pituitary_gland | 1.07643655 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.05099705 |
| 59 | MP0004130_abnormal_muscle_cell | 1.04967879 |
| 60 | MP0005408_hypopigmentation | 1.02275122 |
| 61 | MP0003690_abnormal_glial_cell | 1.00436177 |
| 62 | MP0002132_abnormal_respiratory_system | 0.96194322 |
| 63 | MP0005377_hearing/vestibular/ear_phenot | 0.96063963 |
| 64 | MP0003878_abnormal_ear_physiology | 0.96063963 |
| 65 | MP0003633_abnormal_nervous_system | 0.95622606 |
| 66 | MP0008004_abnormal_stomach_pH | 0.94574928 |
| 67 | MP0003631_nervous_system_phenotype | 0.94563148 |
| 68 | MP0001177_atelectasis | 0.93513470 |
| 69 | MP0002066_abnormal_motor_capabilities/c | 0.89949524 |
| 70 | MP0003866_abnormal_defecation | 0.88706734 |
| 71 | MP0001485_abnormal_pinna_reflex | 0.88360324 |
| 72 | MP0000631_abnormal_neuroendocrine_gland | 0.87695890 |
| 73 | MP0000465_gastrointestinal_hemorrhage | 0.87277150 |
| 74 | MP0001963_abnormal_hearing_physiology | 0.85925983 |
| 75 | MP0004811_abnormal_neuron_physiology | 0.85462342 |
| 76 | MP0010329_abnormal_lipoprotein_level | 0.84932471 |
| 77 | MP0002733_abnormal_thermal_nociception | 0.84147054 |
| 78 | MP0002396_abnormal_hematopoietic_system | 0.83347639 |
| 79 | MP0001873_stomach_inflammation | 0.83296761 |
| 80 | MP0001440_abnormal_grooming_behavior | 0.82646082 |
| 81 | MP0001664_abnormal_digestion | 0.81622078 |
| 82 | MP0002229_neurodegeneration | 0.78580747 |
| 83 | MP0002909_abnormal_adrenal_gland | 0.78412201 |
| 84 | MP0003045_fibrosis | 0.78283877 |
| 85 | MP0003632_abnormal_nervous_system | 0.77557481 |
| 86 | MP0002882_abnormal_neuron_morphology | 0.75732786 |
| 87 | MP0005275_abnormal_skin_tensile | 0.72620959 |
| 88 | MP0010678_abnormal_skin_adnexa | 0.72363651 |
| 89 | MP0001765_abnormal_ion_homeostasis | 0.71306756 |
| 90 | MP0004142_abnormal_muscle_tone | 0.69201818 |
| 91 | MP0001270_distended_abdomen | 0.68325593 |
| 92 | MP0000778_abnormal_nervous_system | 0.67964041 |
| 93 | MP0004019_abnormal_vitamin_homeostasis | 0.66131448 |
| 94 | MP0001849_ear_inflammation | 0.64117455 |
| 95 | MP0003121_genomic_imprinting | 0.60243954 |
| 96 | MP0005666_abnormal_adipose_tissue | 0.59023362 |
| 97 | MP0002933_joint_inflammation | 0.58252865 |
| 98 | MP0000920_abnormal_myelination | 0.55157135 |
| 99 | MP0002653_abnormal_ependyma_morphology | 0.54914860 |
| 100 | MP0002752_abnormal_somatic_nervous | 0.54717905 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pili torti (HP:0003777) | 5.65093694 |
| 2 | Focal seizures (HP:0007359) | 4.52359906 |
| 3 | Myokymia (HP:0002411) | 4.49950900 |
| 4 | Follicular hyperkeratosis (HP:0007502) | 4.03431828 |
| 5 | Febrile seizures (HP:0002373) | 4.00967702 |
| 6 | Obstructive sleep apnea (HP:0002870) | 3.88247378 |
| 7 | Concave nail (HP:0001598) | 3.78658368 |
| 8 | Supranuclear gaze palsy (HP:0000605) | 3.68623362 |
| 9 | Ankle clonus (HP:0011448) | 3.58848993 |
| 10 | Focal motor seizures (HP:0011153) | 3.56202336 |
| 11 | Epileptic encephalopathy (HP:0200134) | 3.55405944 |
| 12 | Atonic seizures (HP:0010819) | 3.33715355 |
| 13 | Abnormal hair laboratory examination (HP:0003328) | 3.26766859 |
| 14 | Annular pancreas (HP:0001734) | 3.17468005 |
| 15 | Distal upper limb amyotrophy (HP:0007149) | 3.07606288 |
| 16 | Upper limb amyotrophy (HP:0009129) | 3.07606288 |
| 17 | Hyperkalemia (HP:0002153) | 3.00070735 |
| 18 | Spontaneous abortion (HP:0005268) | 2.86102747 |
| 19 | Slow-growing hair (HP:0002217) | 2.83552793 |
| 20 | Abnormality of hair growth rate (HP:0011363) | 2.83552793 |
| 21 | Akinesia (HP:0002304) | 2.82783288 |
| 22 | Cerebellar dysplasia (HP:0007033) | 2.75968680 |
| 23 | Hand muscle atrophy (HP:0009130) | 2.73990921 |
| 24 | Spastic gait (HP:0002064) | 2.69500211 |
| 25 | Status epilepticus (HP:0002133) | 2.67980612 |
| 26 | Hemiparesis (HP:0001269) | 2.67800696 |
| 27 | Abnormality of the lower motor neuron (HP:0002366) | 2.67014932 |
| 28 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.60784087 |
| 29 | Abnormality of chloride homeostasis (HP:0011422) | 2.58568027 |
| 30 | Retinal atrophy (HP:0001105) | 2.58177897 |
| 31 | Bronchomalacia (HP:0002780) | 2.56875371 |
| 32 | Mutism (HP:0002300) | 2.53947924 |
| 33 | Neurofibrillary tangles (HP:0002185) | 2.52885284 |
| 34 | Natal tooth (HP:0000695) | 2.49907115 |
| 35 | Peripheral hypomyelination (HP:0007182) | 2.46512162 |
| 36 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.43875549 |
| 37 | Urinary urgency (HP:0000012) | 2.41726852 |
| 38 | Papilledema (HP:0001085) | 2.40958960 |
| 39 | Decreased central vision (HP:0007663) | 2.38351693 |
| 40 | Intrahepatic cholestasis (HP:0001406) | 2.32943731 |
| 41 | Amyloidosis (HP:0011034) | 2.30200328 |
| 42 | Attenuation of retinal blood vessels (HP:0007843) | 2.30148501 |
| 43 | Mask-like facies (HP:0000298) | 2.29791828 |
| 44 | 11 pairs of ribs (HP:0000878) | 2.29630709 |
| 45 | Action tremor (HP:0002345) | 2.29201163 |
| 46 | Abnormality of macular pigmentation (HP:0008002) | 2.28337913 |
| 47 | Torticollis (HP:0000473) | 2.26568810 |
| 48 | Premature skin wrinkling (HP:0100678) | 2.24128445 |
| 49 | Sparse eyelashes (HP:0000653) | 2.21610792 |
| 50 | Postural instability (HP:0002172) | 2.20286005 |
| 51 | Generalized tonic-clonic seizures (HP:0002069) | 2.20025166 |
| 52 | Focal dystonia (HP:0004373) | 2.15970631 |
| 53 | Keratoconjunctivitis sicca (HP:0001097) | 2.15697398 |
| 54 | Abnormal tarsal ossification (HP:0008369) | 2.15480218 |
| 55 | Clonus (HP:0002169) | 2.14727158 |
| 56 | Gaze-evoked nystagmus (HP:0000640) | 2.13369963 |
| 57 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.13095360 |
| 58 | Retinal dysplasia (HP:0007973) | 2.12657500 |
| 59 | Hypophosphatemic rickets (HP:0004912) | 2.09609976 |
| 60 | Keratoconjunctivitis (HP:0001096) | 2.05524391 |
| 61 | Neuronal loss in central nervous system (HP:0002529) | 2.02761253 |
| 62 | Craniofacial dystonia (HP:0012179) | 2.02553500 |
| 63 | Diplopia (HP:0000651) | 2.01760046 |
| 64 | Abnormality of binocular vision (HP:0011514) | 2.01760046 |
| 65 | Progressive cerebellar ataxia (HP:0002073) | 2.00655482 |
| 66 | Abnormality of the periventricular white matter (HP:0002518) | 1.97838799 |
| 67 | Poor eye contact (HP:0000817) | 1.96846540 |
| 68 | Advanced eruption of teeth (HP:0006288) | 1.95095793 |
| 69 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.94451036 |
| 70 | Tracheomalacia (HP:0002779) | 1.92967626 |
| 71 | Type II lissencephaly (HP:0007260) | 1.92790437 |
| 72 | Delayed CNS myelination (HP:0002188) | 1.92671029 |
| 73 | Central scotoma (HP:0000603) | 1.92605444 |
| 74 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.90357731 |
| 75 | Congenital stationary night blindness (HP:0007642) | 1.89923388 |
| 76 | J-shaped sella turcica (HP:0002680) | 1.89499395 |
| 77 | Impaired vibratory sensation (HP:0002495) | 1.89094871 |
| 78 | Brittle hair (HP:0002299) | 1.88877496 |
| 79 | Cerebral inclusion bodies (HP:0100314) | 1.87731708 |
| 80 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.84750629 |
| 81 | Chronic hepatic failure (HP:0100626) | 1.83312901 |
| 82 | Palpebral edema (HP:0100540) | 1.82605103 |
| 83 | Cerebral hypomyelination (HP:0006808) | 1.81494849 |
| 84 | Abnormal eating behavior (HP:0100738) | 1.81235344 |
| 85 | Tetraplegia (HP:0002445) | 1.80151719 |
| 86 | Spinal canal stenosis (HP:0003416) | 1.79195058 |
| 87 | Ventricular fibrillation (HP:0001663) | 1.77523985 |
| 88 | Malnutrition (HP:0004395) | 1.75651783 |
| 89 | Abnormality of the corticospinal tract (HP:0002492) | 1.75059313 |
| 90 | Dialeptic seizures (HP:0011146) | 1.74702775 |
| 91 | Sleep apnea (HP:0010535) | 1.74261411 |
| 92 | Neonatal short-limb short stature (HP:0008921) | 1.74115071 |
| 93 | Lower limb muscle weakness (HP:0007340) | 1.71202470 |
| 94 | Abnormality of saccadic eye movements (HP:0000570) | 1.69829387 |
| 95 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.68496686 |
| 96 | Absence seizures (HP:0002121) | 1.67862807 |
| 97 | Broad alveolar ridges (HP:0000187) | 1.67321049 |
| 98 | Woolly hair (HP:0002224) | 1.66183014 |
| 99 | Absent eyebrow (HP:0002223) | 1.65432006 |
| 100 | Stereotypic behavior (HP:0000733) | 1.64945849 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 4.16002087 |
| 2 | DAPK2 | 3.40911197 |
| 3 | CDK12 | 2.83570414 |
| 4 | MST1R | 2.80140772 |
| 5 | PHKG1 | 2.63373603 |
| 6 | PHKG2 | 2.63373603 |
| 7 | MAP3K9 | 2.44349643 |
| 8 | MAPK13 | 2.27585995 |
| 9 | NTRK3 | 2.25768824 |
| 10 | NME1 | 2.07263602 |
| 11 | EPHA4 | 1.98437655 |
| 12 | MARK1 | 1.97229731 |
| 13 | MAP2K6 | 1.94141587 |
| 14 | WNK1 | 1.91385733 |
| 15 | CAMKK1 | 1.81874866 |
| 16 | AKT3 | 1.76901710 |
| 17 | MAP4K1 | 1.73124331 |
| 18 | KIT | 1.71145764 |
| 19 | SIK2 | 1.70344045 |
| 20 | MAPK12 | 1.64383313 |
| 21 | TNK2 | 1.50087699 |
| 22 | TNIK | 1.48131882 |
| 23 | BRD4 | 1.43464941 |
| 24 | PRKCH | 1.39545376 |
| 25 | CAMKK2 | 1.36841012 |
| 26 | CSF1R | 1.35034539 |
| 27 | LMTK2 | 1.30683066 |
| 28 | RIPK4 | 1.26568179 |
| 29 | DAPK1 | 1.23919163 |
| 30 | EPHA2 | 1.21788553 |
| 31 | MARK2 | 1.18223973 |
| 32 | NTRK2 | 1.17741850 |
| 33 | STK39 | 1.17231177 |
| 34 | OXSR1 | 1.15168756 |
| 35 | CDK19 | 1.14774952 |
| 36 | PAK6 | 1.13142079 |
| 37 | CASK | 1.11981980 |
| 38 | SMG1 | 1.09428149 |
| 39 | CDK5 | 1.08750919 |
| 40 | GRK1 | 1.07683481 |
| 41 | PINK1 | 1.07495560 |
| 42 | MAP3K7 | 1.05870627 |
| 43 | UHMK1 | 1.05191164 |
| 44 | FES | 1.01958054 |
| 45 | PRKAA1 | 0.98333058 |
| 46 | CAMK1 | 0.97511488 |
| 47 | PRKCG | 0.96634165 |
| 48 | RIPK1 | 0.90237186 |
| 49 | MINK1 | 0.85432639 |
| 50 | HIPK2 | 0.85107062 |
| 51 | PRKCI | 0.84009328 |
| 52 | ERN1 | 0.81940203 |
| 53 | SGK1 | 0.81865782 |
| 54 | STK38 | 0.81726680 |
| 55 | SGK2 | 0.81013767 |
| 56 | MAP2K4 | 0.79149128 |
| 57 | ERBB2 | 0.76639543 |
| 58 | GRK5 | 0.74376741 |
| 59 | SGK223 | 0.74248201 |
| 60 | SGK494 | 0.74248201 |
| 61 | MAP2K3 | 0.74228776 |
| 62 | PTK2B | 0.73452350 |
| 63 | PAK3 | 0.71351035 |
| 64 | SGK3 | 0.71269164 |
| 65 | MAP3K6 | 0.65602428 |
| 66 | PDK1 | 0.64976374 |
| 67 | DYRK1A | 0.62210630 |
| 68 | MAPK10 | 0.61775022 |
| 69 | RPS6KB1 | 0.61251738 |
| 70 | TYRO3 | 0.61121060 |
| 71 | IRAK2 | 0.61076923 |
| 72 | MAPK15 | 0.60908082 |
| 73 | PRKD3 | 0.60447465 |
| 74 | STK11 | 0.59905139 |
| 75 | FGFR2 | 0.59790087 |
| 76 | MAPK8 | 0.55146743 |
| 77 | MAP3K4 | 0.52311837 |
| 78 | CSNK1D | 0.51614183 |
| 79 | FYN | 0.50661701 |
| 80 | MAP3K10 | 0.50003265 |
| 81 | SYK | 0.49046027 |
| 82 | PRKG2 | 0.47728231 |
| 83 | CSNK1G1 | 0.47505859 |
| 84 | NEK6 | 0.47369866 |
| 85 | PRKD2 | 0.44325848 |
| 86 | MET | 0.43285191 |
| 87 | GSK3B | 0.42621862 |
| 88 | ICK | 0.41833650 |
| 89 | ITK | 0.41824750 |
| 90 | NTRK1 | 0.41795710 |
| 91 | PRKAA2 | 0.40541904 |
| 92 | PDPK1 | 0.40431436 |
| 93 | CSNK1E | 0.40010628 |
| 94 | CAMK2B | 0.39322620 |
| 95 | SIK1 | 0.38692897 |
| 96 | MAP3K13 | 0.37494072 |
| 97 | PRPF4B | 0.37485904 |
| 98 | RPS6KA3 | 0.36624158 |
| 99 | TESK2 | 0.35721437 |
| 100 | CAMK2A | 0.35599262 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 2.98116361 |
| 2 | Circadian entrainment_Homo sapiens_hsa04713 | 2.47502310 |
| 3 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.43240756 |
| 4 | Salivary secretion_Homo sapiens_hsa04970 | 2.35982512 |
| 5 | ABC transporters_Homo sapiens_hsa02010 | 2.34967541 |
| 6 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.30638659 |
| 7 | Long-term potentiation_Homo sapiens_hsa04720 | 2.25448958 |
| 8 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.08187874 |
| 9 | Morphine addiction_Homo sapiens_hsa05032 | 2.05076832 |
| 10 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.02665250 |
| 11 | Taste transduction_Homo sapiens_hsa04742 | 1.98113921 |
| 12 | Insulin secretion_Homo sapiens_hsa04911 | 1.90928822 |
| 13 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.86999473 |
| 14 | GABAergic synapse_Homo sapiens_hsa04727 | 1.82483084 |
| 15 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.81645293 |
| 16 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.79164105 |
| 17 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.77648996 |
| 18 | Long-term depression_Homo sapiens_hsa04730 | 1.66514693 |
| 19 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.54980831 |
| 20 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.54089277 |
| 21 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.42219238 |
| 22 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.40787547 |
| 23 | Renin secretion_Homo sapiens_hsa04924 | 1.38537839 |
| 24 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.36014584 |
| 25 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.35923958 |
| 26 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.32450973 |
| 27 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.30650301 |
| 28 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.30239740 |
| 29 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.29981857 |
| 30 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.28451001 |
| 31 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.26048730 |
| 32 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.24151519 |
| 33 | Cocaine addiction_Homo sapiens_hsa05030 | 1.23536627 |
| 34 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.23301312 |
| 35 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.20976106 |
| 36 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.18975548 |
| 37 | Bile secretion_Homo sapiens_hsa04976 | 1.17465306 |
| 38 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.15291269 |
| 39 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.14646179 |
| 40 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.12872157 |
| 41 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.09668713 |
| 42 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.08957483 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 1.05834838 |
| 44 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.02782500 |
| 45 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.02003135 |
| 46 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.99323316 |
| 47 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.98947692 |
| 48 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.97425288 |
| 49 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.96410118 |
| 50 | Gap junction_Homo sapiens_hsa04540 | 0.94247011 |
| 51 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.92319405 |
| 52 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.91450666 |
| 53 | Phototransduction_Homo sapiens_hsa04744 | 0.90473756 |
| 54 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.89470117 |
| 55 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.86572571 |
| 56 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.86321075 |
| 57 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.82068976 |
| 58 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.80956069 |
| 59 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.80600065 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.78156125 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.78129551 |
| 62 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.76999597 |
| 63 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76941685 |
| 64 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.76519423 |
| 65 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.75441211 |
| 66 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.75068877 |
| 67 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.74768659 |
| 68 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.74658070 |
| 69 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74132018 |
| 70 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.73018580 |
| 71 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.70897015 |
| 72 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.69961970 |
| 73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.69774229 |
| 74 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.67441737 |
| 75 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.66910408 |
| 76 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.64038042 |
| 77 | Circadian rhythm_Homo sapiens_hsa04710 | 0.63828674 |
| 78 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.63306778 |
| 79 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.63296712 |
| 80 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.62767576 |
| 81 | Platelet activation_Homo sapiens_hsa04611 | 0.62681517 |
| 82 | Axon guidance_Homo sapiens_hsa04360 | 0.62484389 |
| 83 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.61903269 |
| 84 | Insulin resistance_Homo sapiens_hsa04931 | 0.60401141 |
| 85 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.59143981 |
| 86 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.59063207 |
| 87 | Melanogenesis_Homo sapiens_hsa04916 | 0.58953721 |
| 88 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.56700745 |
| 89 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.55740847 |
| 90 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.51350604 |
| 91 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.48455219 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.45999382 |
| 93 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.45180824 |
| 94 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45006525 |
| 95 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.44320547 |
| 96 | Glioma_Homo sapiens_hsa05214 | 0.43829771 |
| 97 | Lysine degradation_Homo sapiens_hsa00310 | 0.43673979 |
| 98 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.42107090 |
| 99 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.41545848 |
| 100 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.40735473 |

