STRCP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1urinary tract smooth muscle contraction (GO:0014848)6.04550017
2regulation of female receptivity (GO:0045924)5.62422841
3tachykinin receptor signaling pathway (GO:0007217)5.49158581
4vocalization behavior (GO:0071625)5.03548207
5synaptic vesicle maturation (GO:0016188)4.97264310
6glutamate secretion (GO:0014047)4.86496919
7female mating behavior (GO:0060180)4.69052077
8positive regulation of uterine smooth muscle contraction (GO:0070474)4.64860940
9positive regulation of vascular permeability (GO:0043117)4.63377538
10maintenance of gastrointestinal epithelium (GO:0030277)4.53158743
11regulation of short-term neuronal synaptic plasticity (GO:0048172)4.52147811
12synaptic vesicle docking involved in exocytosis (GO:0016081)4.51982468
13synaptic vesicle exocytosis (GO:0016079)4.40120939
14positive regulation of action potential (GO:0045760)4.30307475
15synaptic transmission, dopaminergic (GO:0001963)4.18501772
16positive regulation of synapse maturation (GO:0090129)4.18368802
17drinking behavior (GO:0042756)4.16686287
18neuronal action potential propagation (GO:0019227)4.15967768
19positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.14503436
20positive regulation of digestive system process (GO:0060456)4.05684032
21behavioral response to pain (GO:0048266)3.88923785
22positive regulation of synaptic transmission, GABAergic (GO:0032230)3.81876114
23membrane depolarization during action potential (GO:0086010)3.81608901
24regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.80444118
25regulation of synaptic vesicle exocytosis (GO:2000300)3.78904832
26regulation of synapse maturation (GO:0090128)3.78333783
27cerebellar granule cell differentiation (GO:0021707)3.76650853
28regulation of ARF protein signal transduction (GO:0032012)3.75498036
29positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.72393796
30regulation of G0 to G1 transition (GO:0070316)3.66602097
31dendritic spine morphogenesis (GO:0060997)3.65389276
32regulation of uterine smooth muscle contraction (GO:0070472)3.64472611
33synaptic vesicle endocytosis (GO:0048488)3.62542360
34ionotropic glutamate receptor signaling pathway (GO:0035235)3.61575938
35negative regulation of synaptic transmission, GABAergic (GO:0032229)3.55836935
36dicarboxylic acid biosynthetic process (GO:0043650)3.48901919
37response to auditory stimulus (GO:0010996)3.45646549
38regulation of ARF GTPase activity (GO:0032312)3.44936436
39regulation of action potential (GO:0098900)3.41851072
40regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.41523192
41neurotransmitter secretion (GO:0007269)3.38141467
42inositol metabolic process (GO:0006020)3.37265117
43auditory receptor cell stereocilium organization (GO:0060088)3.34599067
44long term synaptic depression (GO:0060292)3.34394344
45regulation of synaptic transmission, GABAergic (GO:0032228)3.29477957
46regulation of synaptic vesicle transport (GO:1902803)3.27661518
47neuron-neuron synaptic transmission (GO:0007270)3.26123057
48neurotransmitter-gated ion channel clustering (GO:0072578)3.23301139
49epithelial structure maintenance (GO:0010669)3.21484038
50G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.18735720
51regulation of long-term neuronal synaptic plasticity (GO:0048169)3.18466522
52regulation of neuronal synaptic plasticity (GO:0048168)3.18403535
53regulation of glutamate receptor signaling pathway (GO:1900449)3.16234849
54glutamate receptor signaling pathway (GO:0007215)3.14205835
55snRNA transcription (GO:0009301)3.14161991
56membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.11582361
57L-amino acid import (GO:0043092)3.10027817
58negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.08505461
59neuronal ion channel clustering (GO:0045161)3.08453392
60dendritic spine organization (GO:0097061)3.02634543
61long-term memory (GO:0007616)3.00513135
62detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.99289301
63sodium ion export (GO:0071436)2.96597512
64cellular potassium ion homeostasis (GO:0030007)2.88832540
65synaptic transmission, glutamatergic (GO:0035249)2.86976006
66positive regulation of neurotransmitter secretion (GO:0001956)2.85828812
67positive regulation of CREB transcription factor activity (GO:0032793)2.83215131
68aggressive behavior (GO:0002118)2.82272340
69phospholipid scrambling (GO:0017121)2.77503619
70regulation of synaptic plasticity (GO:0048167)2.77087319
71membrane depolarization (GO:0051899)2.76919229
72establishment of skin barrier (GO:0061436)2.74861477
73cardiac conduction (GO:0061337)2.72923531
74regulation of neurotransmitter secretion (GO:0046928)2.72855111
75cellular response to epidermal growth factor stimulus (GO:0071364)2.72174144
76locomotory exploration behavior (GO:0035641)2.70006620
77mannose metabolic process (GO:0006013)2.68455443
78regulation of alkaline phosphatase activity (GO:0010692)2.67279439
79adaptation of signaling pathway (GO:0023058)2.65550073
80microtubule nucleation (GO:0007020)2.64965342
81response to pheromone (GO:0019236)2.64538984
82regulation of synapse structural plasticity (GO:0051823)2.64490896
83neurotransmitter transport (GO:0006836)2.63204918
84pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.59829421
85UMP metabolic process (GO:0046049)2.59829421
86pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.59829421
87UMP biosynthetic process (GO:0006222)2.59829421
88gamma-aminobutyric acid signaling pathway (GO:0007214)2.59232518
89cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.58743446
90positive regulation of membrane potential (GO:0045838)2.58199010
91nephron tubule morphogenesis (GO:0072078)2.58126129
92nephron epithelium morphogenesis (GO:0072088)2.58126129
93neuronal action potential (GO:0019228)2.55933792
94positive regulation of exocytosis (GO:0045921)2.55668434
95regulation of excitatory postsynaptic membrane potential (GO:0060079)2.54791627
96cell communication involved in cardiac conduction (GO:0086065)2.52988846
97gamma-aminobutyric acid transport (GO:0015812)2.52137339
98renal tubule morphogenesis (GO:0061333)2.51762953
99negative regulation of digestive system process (GO:0060457)2.50367495
100regulation of female gonad development (GO:2000194)2.46535296

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1DROSHA_22980978_ChIP-Seq_HELA_Human4.34160305
2EZH2_22144423_ChIP-Seq_EOC_Human4.31988393
3CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human3.81986982
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.79714758
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.58255817
6IKZF1_21737484_ChIP-ChIP_HCT116_Human2.33505244
7REST_21632747_ChIP-Seq_MESCs_Mouse2.28301758
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.22174088
9TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.13745539
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.04401980
11GBX2_23144817_ChIP-Seq_PC3_Human2.03005716
12CTCF_27219007_Chip-Seq_Bcells_Human2.00932986
13JARID2_20075857_ChIP-Seq_MESCs_Mouse1.95097789
14RARB_27405468_Chip-Seq_BRAIN_Mouse1.89271018
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.83003238
16ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.80602104
17LXR_22292898_ChIP-Seq_THP-1_Human1.79131640
18ESR2_21235772_ChIP-Seq_MCF-7_Human1.78250287
19EZH2_27294783_Chip-Seq_ESCs_Mouse1.72273575
20DNAJC2_21179169_ChIP-ChIP_NT2_Human1.71988822
21AR_21572438_ChIP-Seq_LNCaP_Human1.71315562
22SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.65413552
23EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.64872759
24SUZ12_27294783_Chip-Seq_ESCs_Mouse1.63110626
25MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.62936688
26JARID2_20064375_ChIP-Seq_MESCs_Mouse1.61698890
27KDM2B_26808549_Chip-Seq_SUP-B15_Human1.59890181
28REST_18959480_ChIP-ChIP_MESCs_Mouse1.57614736
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.56668242
30SMC4_20622854_ChIP-Seq_HELA_Human1.56532118
31SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.56068056
32ERG_21242973_ChIP-ChIP_JURKAT_Human1.54204498
33PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.54150321
34VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.52821372
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51806611
36P68_20966046_ChIP-Seq_HELA_Human1.50571036
37RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.44559615
38KDM2B_26808549_Chip-Seq_K562_Human1.42140846
39KDM2B_26808549_Chip-Seq_DND41_Human1.39871525
40EZH2_18974828_ChIP-Seq_MESCs_Mouse1.39124948
41RNF2_18974828_ChIP-Seq_MESCs_Mouse1.39124948
42ESR1_20079471_ChIP-ChIP_T-47D_Human1.38924549
43CTNNB1_20460455_ChIP-Seq_HCT116_Human1.38902431
44STAT6_21828071_ChIP-Seq_BEAS2B_Human1.35514821
45RNF2_27304074_Chip-Seq_ESCs_Mouse1.35341163
46TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.33613968
47ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.31594100
48SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28643603
49SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.27277791
50ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.26819701
51SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.26391813
52RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.24387743
53OCT4_19829295_ChIP-Seq_ESCs_Human1.24371744
54GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19586579
55E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.17830196
56FOXA2_19822575_ChIP-Seq_HepG2_Human1.17754403
57SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.16206061
58SCL_19346495_ChIP-Seq_HPC-7_Human1.13694675
59CREB1_26743006_Chip-Seq_LNCaP_Human1.13553715
60RACK7_27058665_Chip-Seq_MCF-7_Human1.12189747
61ESR1_21235772_ChIP-Seq_MCF-7_Human1.12043142
62NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.11189526
63CTCF_27219007_Chip-Seq_ERYTHROID_Human1.09903793
64RUNX1_27514584_Chip-Seq_MCF-7_Human1.09479677
65SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.06998236
66ZFP281_18757296_ChIP-ChIP_E14_Mouse1.06111978
67EZH2_27304074_Chip-Seq_ESCs_Mouse1.05782988
68KLF4_19829295_ChIP-Seq_ESCs_Human1.05361654
69SA1_27219007_Chip-Seq_ERYTHROID_Human1.05170538
70CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.05094640
71WDR5_24793694_ChIP-Seq_LNCAP_Human1.04454780
72ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03618644
73MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.01480330
74TCF7_22412390_ChIP-Seq_EML_Mouse1.00512999
75TP63_22573176_ChIP-Seq_HFKS_Human0.97782403
76BCOR_27268052_Chip-Seq_Bcells_Human0.97627069
77TET1_21490601_ChIP-Seq_MESCs_Mouse0.97570649
78SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.96918179
79SA1_27219007_Chip-Seq_Bcells_Human0.96762451
80E2F1_20622854_ChIP-Seq_HELA_Human0.96543660
81KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.96467563
82PHF8_20622854_ChIP-Seq_HELA_Human0.96035357
83WT1_25993318_ChIP-Seq_PODOCYTE_Human0.95219061
84GATA1_19941827_ChIP-Seq_MEL_Mouse0.94749904
85ERA_21632823_ChIP-Seq_H3396_Human0.93409778
86CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.93229838
87SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.91221545
88ZFP281_27345836_Chip-Seq_ESCs_Mouse0.90101363
89SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.90001915
90PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.86608807
91P63_26484246_Chip-Seq_KERATINOCYTES_Human0.86569013
92GATA2_21666600_ChIP-Seq_HMVEC_Human0.86333930
93TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.85674110
94CTCF_20526341_ChIP-Seq_ESCs_Human0.85551567
95GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82046131
96OCT4_20526341_ChIP-Seq_ESCs_Human0.80912828
97UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.79925099
98WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.79090338
99PKCTHETA_26484144_Chip-Seq_BREAST_Human0.78577543
100MYC_19915707_ChIP-ChIP_AK7_Human0.76727059

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.86662835
2MP0009780_abnormal_chondrocyte_physiolo4.01895840
3MP0001968_abnormal_touch/_nociception3.68972082
4MP0004270_analgesia3.55244300
5MP0002736_abnormal_nociception_after3.41700686
6MP0003879_abnormal_hair_cell3.27672772
7MP0002735_abnormal_chemical_nociception2.98106517
8MP0001188_hyperpigmentation2.92039292
9MP0000579_abnormal_nail_morphology2.85644997
10MP0005451_abnormal_body_composition2.83034971
11MP0002734_abnormal_mechanical_nocicepti2.67549059
12MP0003635_abnormal_synaptic_transmissio2.61333929
13MP0004043_abnormal_pH_regulation2.56667022
14MP0004885_abnormal_endolymph2.36614861
15MP0003880_abnormal_central_pattern2.35340067
16MP0008260_abnormal_autophagy2.32612564
17MP0005423_abnormal_somatic_nervous2.30862426
18MP0002822_catalepsy2.30064795
19MP0001348_abnormal_lacrimal_gland2.23310488
20MP0001986_abnormal_taste_sensitivity2.22582336
21MP0009745_abnormal_behavioral_response2.22367668
22MP0005670_abnormal_white_adipose2.11333970
23MP0003787_abnormal_imprinting2.07644259
24MP0004381_abnormal_hair_follicle2.00689718
25MP0002572_abnormal_emotion/affect_behav1.96144252
26MP0002063_abnormal_learning/memory/cond1.95669749
27MP0001661_extended_life_span1.91143612
28MP0002064_seizures1.90471968
29MP0002272_abnormal_nervous_system1.88557453
30MP0004147_increased_porphyrin_level1.85124566
31MP0001501_abnormal_sleep_pattern1.80872205
32MP0002138_abnormal_hepatobiliary_system1.75481325
33MP0001486_abnormal_startle_reflex1.74938339
34MP0008569_lethality_at_weaning1.67326755
35MP0003136_yellow_coat_color1.65735829
36MP0008872_abnormal_physiological_respon1.61904409
37MP0003123_paternal_imprinting1.53244509
38MP0009046_muscle_twitch1.52251953
39MP0005551_abnormal_eye_electrophysiolog1.51259820
40MP0001529_abnormal_vocalization1.40722310
41MP0002277_abnormal_respiratory_mucosa1.34557822
42MP0002098_abnormal_vibrissa_morphology1.33767140
43MP0001970_abnormal_pain_threshold1.30373453
44MP0006292_abnormal_olfactory_placode1.30103057
45MP0003122_maternal_imprinting1.27016834
46MP0004924_abnormal_behavior1.25322982
47MP0005386_behavior/neurological_phenoty1.25322982
48MP0004742_abnormal_vestibular_system1.24915689
49MP0006276_abnormal_autonomic_nervous1.21888746
50MP0002067_abnormal_sensory_capabilities1.20636058
51MP0002557_abnormal_social/conspecific_i1.20285487
52MP0001502_abnormal_circadian_rhythm1.19648636
53MP0000427_abnormal_hair_cycle1.18705603
54MP0000383_abnormal_hair_follicle1.15438664
55MP0003329_amyloid_beta_deposits1.13234652
56MP0005535_abnormal_body_temperature1.07850290
57MP0005646_abnormal_pituitary_gland1.07643655
58MP0002876_abnormal_thyroid_physiology1.05099705
59MP0004130_abnormal_muscle_cell1.04967879
60MP0005408_hypopigmentation1.02275122
61MP0003690_abnormal_glial_cell1.00436177
62MP0002132_abnormal_respiratory_system0.96194322
63MP0005377_hearing/vestibular/ear_phenot0.96063963
64MP0003878_abnormal_ear_physiology0.96063963
65MP0003633_abnormal_nervous_system0.95622606
66MP0008004_abnormal_stomach_pH0.94574928
67MP0003631_nervous_system_phenotype0.94563148
68MP0001177_atelectasis0.93513470
69MP0002066_abnormal_motor_capabilities/c0.89949524
70MP0003866_abnormal_defecation0.88706734
71MP0001485_abnormal_pinna_reflex0.88360324
72MP0000631_abnormal_neuroendocrine_gland0.87695890
73MP0000465_gastrointestinal_hemorrhage0.87277150
74MP0001963_abnormal_hearing_physiology0.85925983
75MP0004811_abnormal_neuron_physiology0.85462342
76MP0010329_abnormal_lipoprotein_level0.84932471
77MP0002733_abnormal_thermal_nociception0.84147054
78MP0002396_abnormal_hematopoietic_system0.83347639
79MP0001873_stomach_inflammation0.83296761
80MP0001440_abnormal_grooming_behavior0.82646082
81MP0001664_abnormal_digestion0.81622078
82MP0002229_neurodegeneration0.78580747
83MP0002909_abnormal_adrenal_gland0.78412201
84MP0003045_fibrosis0.78283877
85MP0003632_abnormal_nervous_system0.77557481
86MP0002882_abnormal_neuron_morphology0.75732786
87MP0005275_abnormal_skin_tensile0.72620959
88MP0010678_abnormal_skin_adnexa0.72363651
89MP0001765_abnormal_ion_homeostasis0.71306756
90MP0004142_abnormal_muscle_tone0.69201818
91MP0001270_distended_abdomen0.68325593
92MP0000778_abnormal_nervous_system0.67964041
93MP0004019_abnormal_vitamin_homeostasis0.66131448
94MP0001849_ear_inflammation0.64117455
95MP0003121_genomic_imprinting0.60243954
96MP0005666_abnormal_adipose_tissue0.59023362
97MP0002933_joint_inflammation0.58252865
98MP0000920_abnormal_myelination0.55157135
99MP0002653_abnormal_ependyma_morphology0.54914860
100MP0002752_abnormal_somatic_nervous0.54717905

Predicted human phenotypes

RankGene SetZ-score
1Pili torti (HP:0003777)5.65093694
2Focal seizures (HP:0007359)4.52359906
3Myokymia (HP:0002411)4.49950900
4Follicular hyperkeratosis (HP:0007502)4.03431828
5Febrile seizures (HP:0002373)4.00967702
6Obstructive sleep apnea (HP:0002870)3.88247378
7Concave nail (HP:0001598)3.78658368
8Supranuclear gaze palsy (HP:0000605)3.68623362
9Ankle clonus (HP:0011448)3.58848993
10Focal motor seizures (HP:0011153)3.56202336
11Epileptic encephalopathy (HP:0200134)3.55405944
12Atonic seizures (HP:0010819)3.33715355
13Abnormal hair laboratory examination (HP:0003328)3.26766859
14Annular pancreas (HP:0001734)3.17468005
15Distal upper limb amyotrophy (HP:0007149)3.07606288
16Upper limb amyotrophy (HP:0009129)3.07606288
17Hyperkalemia (HP:0002153)3.00070735
18Spontaneous abortion (HP:0005268)2.86102747
19Slow-growing hair (HP:0002217)2.83552793
20Abnormality of hair growth rate (HP:0011363)2.83552793
21Akinesia (HP:0002304)2.82783288
22Cerebellar dysplasia (HP:0007033)2.75968680
23Hand muscle atrophy (HP:0009130)2.73990921
24Spastic gait (HP:0002064)2.69500211
25Status epilepticus (HP:0002133)2.67980612
26Hemiparesis (HP:0001269)2.67800696
27Abnormality of the lower motor neuron (HP:0002366)2.67014932
28Urinary bladder sphincter dysfunction (HP:0002839)2.60784087
29Abnormality of chloride homeostasis (HP:0011422)2.58568027
30Retinal atrophy (HP:0001105)2.58177897
31Bronchomalacia (HP:0002780)2.56875371
32Mutism (HP:0002300)2.53947924
33Neurofibrillary tangles (HP:0002185)2.52885284
34Natal tooth (HP:0000695)2.49907115
35Peripheral hypomyelination (HP:0007182)2.46512162
36Impaired vibration sensation in the lower limbs (HP:0002166)2.43875549
37Urinary urgency (HP:0000012)2.41726852
38Papilledema (HP:0001085)2.40958960
39Decreased central vision (HP:0007663)2.38351693
40Intrahepatic cholestasis (HP:0001406)2.32943731
41Amyloidosis (HP:0011034)2.30200328
42Attenuation of retinal blood vessels (HP:0007843)2.30148501
43Mask-like facies (HP:0000298)2.29791828
4411 pairs of ribs (HP:0000878)2.29630709
45Action tremor (HP:0002345)2.29201163
46Abnormality of macular pigmentation (HP:0008002)2.28337913
47Torticollis (HP:0000473)2.26568810
48Premature skin wrinkling (HP:0100678)2.24128445
49Sparse eyelashes (HP:0000653)2.21610792
50Postural instability (HP:0002172)2.20286005
51Generalized tonic-clonic seizures (HP:0002069)2.20025166
52Focal dystonia (HP:0004373)2.15970631
53Keratoconjunctivitis sicca (HP:0001097)2.15697398
54Abnormal tarsal ossification (HP:0008369)2.15480218
55Clonus (HP:0002169)2.14727158
56Gaze-evoked nystagmus (HP:0000640)2.13369963
57Abnormal rod and cone electroretinograms (HP:0008323)2.13095360
58Retinal dysplasia (HP:0007973)2.12657500
59Hypophosphatemic rickets (HP:0004912)2.09609976
60Keratoconjunctivitis (HP:0001096)2.05524391
61Neuronal loss in central nervous system (HP:0002529)2.02761253
62Craniofacial dystonia (HP:0012179)2.02553500
63Diplopia (HP:0000651)2.01760046
64Abnormality of binocular vision (HP:0011514)2.01760046
65Progressive cerebellar ataxia (HP:0002073)2.00655482
66Abnormality of the periventricular white matter (HP:0002518)1.97838799
67Poor eye contact (HP:0000817)1.96846540
68Advanced eruption of teeth (HP:0006288)1.95095793
69Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.94451036
70Tracheomalacia (HP:0002779)1.92967626
71Type II lissencephaly (HP:0007260)1.92790437
72Delayed CNS myelination (HP:0002188)1.92671029
73Central scotoma (HP:0000603)1.92605444
74Bilateral sensorineural hearing impairment (HP:0008619)1.90357731
75Congenital stationary night blindness (HP:0007642)1.89923388
76J-shaped sella turcica (HP:0002680)1.89499395
77Impaired vibratory sensation (HP:0002495)1.89094871
78Brittle hair (HP:0002299)1.88877496
79Cerebral inclusion bodies (HP:0100314)1.87731708
80Bony spicule pigmentary retinopathy (HP:0007737)1.84750629
81Chronic hepatic failure (HP:0100626)1.83312901
82Palpebral edema (HP:0100540)1.82605103
83Cerebral hypomyelination (HP:0006808)1.81494849
84Abnormal eating behavior (HP:0100738)1.81235344
85Tetraplegia (HP:0002445)1.80151719
86Spinal canal stenosis (HP:0003416)1.79195058
87Ventricular fibrillation (HP:0001663)1.77523985
88Malnutrition (HP:0004395)1.75651783
89Abnormality of the corticospinal tract (HP:0002492)1.75059313
90Dialeptic seizures (HP:0011146)1.74702775
91Sleep apnea (HP:0010535)1.74261411
92Neonatal short-limb short stature (HP:0008921)1.74115071
93Lower limb muscle weakness (HP:0007340)1.71202470
94Abnormality of saccadic eye movements (HP:0000570)1.69829387
95Morphological abnormality of the pyramidal tract (HP:0002062)1.68496686
96Absence seizures (HP:0002121)1.67862807
97Broad alveolar ridges (HP:0000187)1.67321049
98Woolly hair (HP:0002224)1.66183014
99Absent eyebrow (HP:0002223)1.65432006
100Stereotypic behavior (HP:0000733)1.64945849

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK44.16002087
2DAPK23.40911197
3CDK122.83570414
4MST1R2.80140772
5PHKG12.63373603
6PHKG22.63373603
7MAP3K92.44349643
8MAPK132.27585995
9NTRK32.25768824
10NME12.07263602
11EPHA41.98437655
12MARK11.97229731
13MAP2K61.94141587
14WNK11.91385733
15CAMKK11.81874866
16AKT31.76901710
17MAP4K11.73124331
18KIT1.71145764
19SIK21.70344045
20MAPK121.64383313
21TNK21.50087699
22TNIK1.48131882
23BRD41.43464941
24PRKCH1.39545376
25CAMKK21.36841012
26CSF1R1.35034539
27LMTK21.30683066
28RIPK41.26568179
29DAPK11.23919163
30EPHA21.21788553
31MARK21.18223973
32NTRK21.17741850
33STK391.17231177
34OXSR11.15168756
35CDK191.14774952
36PAK61.13142079
37CASK1.11981980
38SMG11.09428149
39CDK51.08750919
40GRK11.07683481
41PINK11.07495560
42MAP3K71.05870627
43UHMK11.05191164
44FES1.01958054
45PRKAA10.98333058
46CAMK10.97511488
47PRKCG0.96634165
48RIPK10.90237186
49MINK10.85432639
50HIPK20.85107062
51PRKCI0.84009328
52ERN10.81940203
53SGK10.81865782
54STK380.81726680
55SGK20.81013767
56MAP2K40.79149128
57ERBB20.76639543
58GRK50.74376741
59SGK2230.74248201
60SGK4940.74248201
61MAP2K30.74228776
62PTK2B0.73452350
63PAK30.71351035
64SGK30.71269164
65MAP3K60.65602428
66PDK10.64976374
67DYRK1A0.62210630
68MAPK100.61775022
69RPS6KB10.61251738
70TYRO30.61121060
71IRAK20.61076923
72MAPK150.60908082
73PRKD30.60447465
74STK110.59905139
75FGFR20.59790087
76MAPK80.55146743
77MAP3K40.52311837
78CSNK1D0.51614183
79FYN0.50661701
80MAP3K100.50003265
81SYK0.49046027
82PRKG20.47728231
83CSNK1G10.47505859
84NEK60.47369866
85PRKD20.44325848
86MET0.43285191
87GSK3B0.42621862
88ICK0.41833650
89ITK0.41824750
90NTRK10.41795710
91PRKAA20.40541904
92PDPK10.40431436
93CSNK1E0.40010628
94CAMK2B0.39322620
95SIK10.38692897
96MAP3K130.37494072
97PRPF4B0.37485904
98RPS6KA30.36624158
99TESK20.35721437
100CAMK2A0.35599262

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.98116361
2Circadian entrainment_Homo sapiens_hsa047132.47502310
3Glutamatergic synapse_Homo sapiens_hsa047242.43240756
4Salivary secretion_Homo sapiens_hsa049702.35982512
5ABC transporters_Homo sapiens_hsa020102.34967541
6Synaptic vesicle cycle_Homo sapiens_hsa047212.30638659
7Long-term potentiation_Homo sapiens_hsa047202.25448958
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.08187874
9Morphine addiction_Homo sapiens_hsa050322.05076832
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.02665250
11Taste transduction_Homo sapiens_hsa047421.98113921
12Insulin secretion_Homo sapiens_hsa049111.90928822
13Phosphatidylinositol signaling system_Homo sapiens_hsa040701.86999473
14GABAergic synapse_Homo sapiens_hsa047271.82483084
15Calcium signaling pathway_Homo sapiens_hsa040201.81645293
16Aldosterone synthesis and secretion_Homo sapiens_hsa049251.79164105
17Amphetamine addiction_Homo sapiens_hsa050311.77648996
18Long-term depression_Homo sapiens_hsa047301.66514693
19Primary bile acid biosynthesis_Homo sapiens_hsa001201.54980831
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.54089277
21Gastric acid secretion_Homo sapiens_hsa049711.42219238
22Cholinergic synapse_Homo sapiens_hsa047251.40787547
23Renin secretion_Homo sapiens_hsa049241.38537839
24Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.36014584
25Dopaminergic synapse_Homo sapiens_hsa047281.35923958
26Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.32450973
27Inositol phosphate metabolism_Homo sapiens_hsa005621.30650301
28Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.30239740
29Arginine biosynthesis_Homo sapiens_hsa002201.29981857
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.28451001
31Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.26048730
32Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.24151519
33Cocaine addiction_Homo sapiens_hsa050301.23536627
34Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.23301312
35GnRH signaling pathway_Homo sapiens_hsa049121.20976106
36Fructose and mannose metabolism_Homo sapiens_hsa000511.18975548
37Bile secretion_Homo sapiens_hsa049761.17465306
38Vascular smooth muscle contraction_Homo sapiens_hsa042701.15291269
39Serotonergic synapse_Homo sapiens_hsa047261.14646179
40cAMP signaling pathway_Homo sapiens_hsa040241.12872157
41Ovarian steroidogenesis_Homo sapiens_hsa049131.09668713
42Oxytocin signaling pathway_Homo sapiens_hsa049211.08957483
43Olfactory transduction_Homo sapiens_hsa047401.05834838
44Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.02782500
45Thyroid hormone signaling pathway_Homo sapiens_hsa049191.02003135
46Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99323316
47Vibrio cholerae infection_Homo sapiens_hsa051100.98947692
48Phospholipase D signaling pathway_Homo sapiens_hsa040720.97425288
49Pancreatic secretion_Homo sapiens_hsa049720.96410118
50Gap junction_Homo sapiens_hsa045400.94247011
51Glycerophospholipid metabolism_Homo sapiens_hsa005640.92319405
52Type II diabetes mellitus_Homo sapiens_hsa049300.91450666
53Phototransduction_Homo sapiens_hsa047440.90473756
54Choline metabolism in cancer_Homo sapiens_hsa052310.89470117
55Thyroid hormone synthesis_Homo sapiens_hsa049180.86572571
56Cyanoamino acid metabolism_Homo sapiens_hsa004600.86321075
57Fatty acid biosynthesis_Homo sapiens_hsa000610.82068976
58cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80956069
59Chemical carcinogenesis_Homo sapiens_hsa052040.80600065
60Butanoate metabolism_Homo sapiens_hsa006500.78156125
61Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78129551
62Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.76999597
63Tryptophan metabolism_Homo sapiens_hsa003800.76941685
64Vitamin digestion and absorption_Homo sapiens_hsa049770.76519423
65Longevity regulating pathway - mammal_Homo sapiens_hsa042110.75441211
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.75068877
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.74768659
68Arginine and proline metabolism_Homo sapiens_hsa003300.74658070
69Collecting duct acid secretion_Homo sapiens_hsa049660.74132018
70African trypanosomiasis_Homo sapiens_hsa051430.73018580
71Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70897015
72Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.69961970
73Regulation of autophagy_Homo sapiens_hsa041400.69774229
74Nitrogen metabolism_Homo sapiens_hsa009100.67441737
75mTOR signaling pathway_Homo sapiens_hsa041500.66910408
76MAPK signaling pathway_Homo sapiens_hsa040100.64038042
77Circadian rhythm_Homo sapiens_hsa047100.63828674
78Estrogen signaling pathway_Homo sapiens_hsa049150.63306778
79VEGF signaling pathway_Homo sapiens_hsa043700.63296712
80Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.62767576
81Platelet activation_Homo sapiens_hsa046110.62681517
82Axon guidance_Homo sapiens_hsa043600.62484389
83Glycerolipid metabolism_Homo sapiens_hsa005610.61903269
84Insulin resistance_Homo sapiens_hsa049310.60401141
85Glucagon signaling pathway_Homo sapiens_hsa049220.59143981
86Acute myeloid leukemia_Homo sapiens_hsa052210.59063207
87Melanogenesis_Homo sapiens_hsa049160.58953721
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.56700745
89Oocyte meiosis_Homo sapiens_hsa041140.55740847
90PPAR signaling pathway_Homo sapiens_hsa033200.51350604
91ErbB signaling pathway_Homo sapiens_hsa040120.48455219
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.45999382
93alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.45180824
94Retinol metabolism_Homo sapiens_hsa008300.45006525
95Ras signaling pathway_Homo sapiens_hsa040140.44320547
96Glioma_Homo sapiens_hsa052140.43829771
97Lysine degradation_Homo sapiens_hsa003100.43673979
98Selenocompound metabolism_Homo sapiens_hsa004500.42107090
99Linoleic acid metabolism_Homo sapiens_hsa005910.41545848
100Notch signaling pathway_Homo sapiens_hsa043300.40735473

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »