STX12

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)4.83070469
2pyrimidine nucleobase catabolic process (GO:0006208)4.44399525
3vocalization behavior (GO:0071625)4.33061889
4* synaptic vesicle exocytosis (GO:0016079)4.30683199
5regulation of short-term neuronal synaptic plasticity (GO:0048172)4.13253465
6regulation of synaptic vesicle exocytosis (GO:2000300)4.06743233
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.02361208
8cell migration in hindbrain (GO:0021535)3.96081671
9protein localization to synapse (GO:0035418)3.91729040
10regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.87105507
11neuron recognition (GO:0008038)3.83422734
12glutamate secretion (GO:0014047)3.81279410
13regulation of cAMP-dependent protein kinase activity (GO:2000479)3.81122103
14positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.75447003
15synaptic vesicle maturation (GO:0016188)3.73388129
16axonal fasciculation (GO:0007413)3.70410488
17nucleobase catabolic process (GO:0046113)3.67671277
18positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.66821377
19synaptic vesicle endocytosis (GO:0048488)3.59576738
20locomotory exploration behavior (GO:0035641)3.51936187
21regulation of glutamate receptor signaling pathway (GO:1900449)3.50965927
22presynaptic membrane assembly (GO:0097105)3.50657747
23layer formation in cerebral cortex (GO:0021819)3.44690997
24regulation of synaptic vesicle transport (GO:1902803)3.38112843
25establishment of mitochondrion localization (GO:0051654)3.35084169
26ionotropic glutamate receptor signaling pathway (GO:0035235)3.28603983
27postsynaptic membrane organization (GO:0001941)3.27227095
28dendritic spine morphogenesis (GO:0060997)3.27056674
29presynaptic membrane organization (GO:0097090)3.24489850
30exploration behavior (GO:0035640)3.23610739
31regulation of respiratory system process (GO:0044065)3.21478764
32neuronal action potential propagation (GO:0019227)3.19270713
33negative regulation of microtubule polymerization (GO:0031115)3.17648932
34glutamate receptor signaling pathway (GO:0007215)3.17589391
35neurotransmitter secretion (GO:0007269)3.17202828
36regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.15712731
37regulation of neuronal synaptic plasticity (GO:0048168)3.11592391
38synaptic vesicle docking involved in exocytosis (GO:0016081)3.11442364
39response to dietary excess (GO:0002021)3.10269450
40negative regulation of neurotransmitter transport (GO:0051589)3.08771713
41regulation of long-term neuronal synaptic plasticity (GO:0048169)3.04320503
42proline transport (GO:0015824)3.04190696
43dendrite morphogenesis (GO:0048813)3.03634399
44neuron-neuron synaptic transmission (GO:0007270)2.99903130
45regulation of synapse structural plasticity (GO:0051823)2.99106510
46positive regulation of synapse assembly (GO:0051965)2.98197924
47cerebellar granule cell differentiation (GO:0021707)2.93433774
48regulation of excitatory postsynaptic membrane potential (GO:0060079)2.92656981
49synaptic transmission, glutamatergic (GO:0035249)2.92168057
50regulation of dendritic spine morphogenesis (GO:0061001)2.90434552
51neurotransmitter-gated ion channel clustering (GO:0072578)2.90415367
52negative regulation of synaptic transmission, GABAergic (GO:0032229)2.88618324
53transmission of nerve impulse (GO:0019226)2.88606756
54positive regulation of synapse maturation (GO:0090129)2.88593351
55long-term synaptic potentiation (GO:0060291)2.86572555
56regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.83245878
57organelle transport along microtubule (GO:0072384)2.82638692
58gamma-aminobutyric acid signaling pathway (GO:0007214)2.82573711
59glycosphingolipid biosynthetic process (GO:0006688)2.81732671
60establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.79722419
61mitochondrion transport along microtubule (GO:0047497)2.79722419
62regulation of postsynaptic membrane potential (GO:0060078)2.79019670
63negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.78816793
64neuromuscular process controlling posture (GO:0050884)2.76720534
65positive regulation of dendritic spine morphogenesis (GO:0061003)2.74923157
66synapse assembly (GO:0007416)2.74681264
67regulation of synaptic plasticity (GO:0048167)2.74323445
68membrane assembly (GO:0071709)2.73588239
69regulation of respiratory gaseous exchange (GO:0043576)2.72743956
70innervation (GO:0060384)2.72333013
71neuromuscular process controlling balance (GO:0050885)2.71016936
72regulation of neurotransmitter secretion (GO:0046928)2.69022621
73neurotransmitter transport (GO:0006836)2.67528214
74membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.65762813
75neuromuscular process (GO:0050905)2.64664900
76dendrite development (GO:0016358)2.64511990
77vesicle transport along microtubule (GO:0047496)2.63783852
78gamma-aminobutyric acid transport (GO:0015812)2.63572740
79G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.63447344
80negative regulation of neurotransmitter secretion (GO:0046929)2.63057019
81axon extension (GO:0048675)2.62534439
82regulation of synaptic transmission, glutamatergic (GO:0051966)2.62472472
83central nervous system projection neuron axonogenesis (GO:0021952)2.61016799
84cerebral cortex radially oriented cell migration (GO:0021799)2.59783904
85ATP hydrolysis coupled proton transport (GO:0015991)2.58645561
86energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.58645561
87protein neddylation (GO:0045116)2.58414259
88positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.58358358
89* establishment of synaptic vesicle localization (GO:0097480)2.56546795
90* synaptic vesicle transport (GO:0048489)2.56546795
91negative regulation of dendrite morphogenesis (GO:0050774)2.56479296
92response to histamine (GO:0034776)2.55566955
93* establishment of vesicle localization (GO:0051650)2.53045604
94synapse organization (GO:0050808)2.51771193
95mating behavior (GO:0007617)2.51029037
96regulation of neurotransmitter transport (GO:0051588)2.49549858
97regulation of dendritic spine development (GO:0060998)2.49335162
98regulation of voltage-gated calcium channel activity (GO:1901385)2.48308933
99learning (GO:0007612)2.48108631
100negative regulation of JAK-STAT cascade (GO:0046426)2.47857062
101regulation of vesicle fusion (GO:0031338)2.47777378
102negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.47665927
103activation of protein kinase A activity (GO:0034199)2.47285570
104positive regulation of dendritic spine development (GO:0060999)2.46958726
105regulation of clathrin-mediated endocytosis (GO:2000369)2.46797064
106positive regulation of membrane potential (GO:0045838)2.45761537
107neuronal ion channel clustering (GO:0045161)2.45510043
108acidic amino acid transport (GO:0015800)2.43020778
109neurofilament cytoskeleton organization (GO:0060052)2.42698560
110clathrin coat assembly (GO:0048268)2.38849488
111positive regulation of vesicle fusion (GO:0031340)2.37835009
112regulation of chemokine-mediated signaling pathway (GO:0070099)2.37267695
113neuron projection extension (GO:1990138)2.36904885
114negative regulation of amino acid transport (GO:0051956)2.34573139
115ganglioside metabolic process (GO:0001573)2.32962482
116regulation of fever generation (GO:0031620)2.32692851
117calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.32126247
118macroautophagy (GO:0016236)2.27808954
119L-serine transport (GO:0015825)2.24236694
120cellular potassium ion homeostasis (GO:0030007)2.23283926
121response to auditory stimulus (GO:0010996)2.23191147
122protein localization to cilium (GO:0061512)2.22990428
123sodium ion export (GO:0071436)2.22235588
124auditory behavior (GO:0031223)2.22075557
125regulation of amino acid transport (GO:0051955)2.21256807
126L-glutamate transport (GO:0015813)2.18408930
127serine transport (GO:0032329)2.18257304
128positive regulation of heat generation (GO:0031652)2.17640759
129dendritic spine organization (GO:0097061)2.17012826
130detection of calcium ion (GO:0005513)2.16783576
131nerve growth factor signaling pathway (GO:0038180)2.14769838
132positive regulation of axon extension (GO:0045773)2.10362631
133L-amino acid import (GO:0043092)2.10325169
134negative regulation of synaptic transmission (GO:0050805)2.07725370
135establishment of melanosome localization (GO:0032401)2.06319817
136regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.05851665
137positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.05639513
138chondroitin sulfate catabolic process (GO:0030207)2.04913338
139endoplasmic reticulum organization (GO:0007029)2.03686643
140astrocyte differentiation (GO:0048708)2.03489212
141regulation of heat generation (GO:0031650)2.03337146
142establishment of pigment granule localization (GO:0051905)2.00423403
143startle response (GO:0001964)2.00350985
144amino acid import (GO:0043090)1.99885401
145Rac protein signal transduction (GO:0016601)1.99611602
146melanosome transport (GO:0032402)1.98100162
147regulation of neurotransmitter levels (GO:0001505)1.98050219

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.83250486
2GBX2_23144817_ChIP-Seq_PC3_Human3.49876182
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.85361627
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.69737981
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.65273896
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.40340659
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.40340659
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.40304616
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.36494395
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.36347614
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.34022999
12REST_21632747_ChIP-Seq_MESCs_Mouse2.33589396
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.30914444
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.20303555
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.15768180
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.13857866
17RNF2_27304074_Chip-Seq_ESCs_Mouse2.02093278
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.00338744
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.95526805
20AR_21572438_ChIP-Seq_LNCaP_Human1.92585393
21REST_18959480_ChIP-ChIP_MESCs_Mouse1.89822827
22ERG_21242973_ChIP-ChIP_JURKAT_Human1.88995824
23EZH2_27294783_Chip-Seq_ESCs_Mouse1.87908153
24CTBP2_25329375_ChIP-Seq_LNCAP_Human1.83087602
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.80659764
26RARB_27405468_Chip-Seq_BRAIN_Mouse1.79417060
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74175601
28DROSHA_22980978_ChIP-Seq_HELA_Human1.69937461
29TAF15_26573619_Chip-Seq_HEK293_Human1.65879873
30NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.63824332
31NRF2_20460467_ChIP-Seq_MEFs_Mouse1.63824332
32GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.62955835
33WT1_19549856_ChIP-ChIP_CCG9911_Human1.62936226
34VDR_22108803_ChIP-Seq_LS180_Human1.59834461
35IGF1R_20145208_ChIP-Seq_DFB_Human1.58252111
36ZFP57_27257070_Chip-Seq_ESCs_Mouse1.57789496
37PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.57320705
38SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53232227
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.52483477
40CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.50638718
41BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.50247233
42RNF2_27304074_Chip-Seq_NSC_Mouse1.46193684
43PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.46151829
44SMAD4_21799915_ChIP-Seq_A2780_Human1.43302901
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41347236
46EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39193257
47ZNF274_21170338_ChIP-Seq_K562_Hela1.39054075
48P300_19829295_ChIP-Seq_ESCs_Human1.38356718
49IKZF1_21737484_ChIP-ChIP_HCT116_Human1.36818499
50RING1B_27294783_Chip-Seq_NPCs_Mouse1.36717683
51RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.35559255
52ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.34328736
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.34000614
54CDX2_19796622_ChIP-Seq_MESCs_Mouse1.33653094
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32469308
56FUS_26573619_Chip-Seq_HEK293_Human1.31501782
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31372607
58PIAS1_25552417_ChIP-Seq_VCAP_Human1.31096292
59TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.30307116
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.29131301
61NANOG_18555785_Chip-Seq_ESCs_Mouse1.27947623
62TP53_18474530_ChIP-ChIP_U2OS_Human1.27648937
63Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.26386454
64MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.26070828
65NR3C1_23031785_ChIP-Seq_PC12_Mouse1.25671185
66ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.22981372
67RING1B_27294783_Chip-Seq_ESCs_Mouse1.22862683
68NR3C1_21868756_ChIP-Seq_MCF10A_Human1.22615851
69TRIM28_21343339_ChIP-Seq_HEK293_Human1.22071083
70* SOX2_21211035_ChIP-Seq_LN229_Gbm1.21684161
71RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.21398546
72P53_22127205_ChIP-Seq_FIBROBLAST_Human1.21146784
73EP300_21415370_ChIP-Seq_HL-1_Mouse1.17045697
74STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.14389745
75EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13271872
76AR_25329375_ChIP-Seq_VCAP_Human1.12625608
77SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.11566425
78STAT3_23295773_ChIP-Seq_U87_Human1.11288150
79SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.08789399
80MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.08479238
81CJUN_26792858_Chip-Seq_BT549_Human1.08233904
82SMAD_19615063_ChIP-ChIP_OVARY_Human1.08108023
83TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07918289
84TP53_16413492_ChIP-PET_HCT116_Human1.07287034
85POU3F2_20337985_ChIP-ChIP_501MEL_Human1.07110679
86SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06519075
87WT1_25993318_ChIP-Seq_PODOCYTE_Human1.06014138
88ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05285871
89TP53_20018659_ChIP-ChIP_R1E_Mouse1.04838846
90TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.04798895
91AHR_22903824_ChIP-Seq_MCF-7_Human1.04604781
92GATA2_21666600_ChIP-Seq_HMVEC_Human1.03155147
93TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03025384
94CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.02120127
95YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01619854
96ARNT_22903824_ChIP-Seq_MCF-7_Human1.01420118
97CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.01336286
98P53_22387025_ChIP-Seq_ESCs_Mouse1.01323471
99E2F1_18555785_Chip-Seq_ESCs_Mouse1.00384937
100ZFP281_18757296_ChIP-ChIP_E14_Mouse1.00376773
101ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00289037
102AR_19668381_ChIP-Seq_PC3_Human0.99929212
103BCAT_22108803_ChIP-Seq_LS180_Human0.99484253
104CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.98739263
105TAL1_26923725_Chip-Seq_HPCs_Mouse0.97777683
106ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.97530761
107CMYC_18555785_Chip-Seq_ESCs_Mouse0.97464680
108CBP_20019798_ChIP-Seq_JUKART_Human0.96803242
109IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96803242
110TCF4_23295773_ChIP-Seq_U87_Human0.96413476
111VDR_24787735_ChIP-Seq_THP-1_Human0.94096795
112KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.94080472
113MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.92409044
114RUNX2_22187159_ChIP-Seq_PCA_Human0.92279444
115AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92013786
116MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.91418000
117GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91165302
118JUN_21703547_ChIP-Seq_K562_Human0.90790477
119SUZ12_18555785_Chip-Seq_ESCs_Mouse0.90185978
120UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90109400
121KDM2B_26808549_Chip-Seq_REH_Human0.90104671
122TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89915535
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89915535
124OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.89880086
125NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.89785296
126CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89544446
127GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.89316759
128KDM2B_26808549_Chip-Seq_K562_Human0.88229503
129WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.87802739
130LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87591603

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.49045372
2MP0003880_abnormal_central_pattern4.34660441
3MP0003635_abnormal_synaptic_transmissio3.28439327
4MP0004270_analgesia3.25275357
5MP0002063_abnormal_learning/memory/cond2.89799156
6MP0005171_absent_coat_pigmentation2.78524190
7MP0002064_seizures2.73896710
8MP0009046_muscle_twitch2.66515334
9MP0002572_abnormal_emotion/affect_behav2.56778247
10MP0009745_abnormal_behavioral_response2.55293234
11MP0001968_abnormal_touch/_nociception2.54781553
12MP0002734_abnormal_mechanical_nocicepti2.50530038
13MP0000778_abnormal_nervous_system2.49672664
14MP0002736_abnormal_nociception_after2.23616918
15MP0002272_abnormal_nervous_system2.20920772
16MP0002733_abnormal_thermal_nociception2.17398370
17MP0001440_abnormal_grooming_behavior2.10846263
18MP0006276_abnormal_autonomic_nervous2.07408027
19MP0002735_abnormal_chemical_nociception2.07181081
20MP0008438_abnormal_cutaneous_collagen2.06522951
21MP0001970_abnormal_pain_threshold2.06338317
22MP0000569_abnormal_digit_pigmentation2.04675452
23MP0002184_abnormal_innervation2.01595123
24MP0000604_amyloidosis2.00137743
25MP0002638_abnormal_pupillary_reflex1.97355865
26MP0005423_abnormal_somatic_nervous1.97118700
27MP0001486_abnormal_startle_reflex1.93037809
28MP0003303_peritoneal_inflammation1.90960113
29MP0002067_abnormal_sensory_capabilities1.78705661
30MP0001984_abnormal_olfaction1.78687304
31MP0005167_abnormal_blood-brain_barrier1.74993379
32MP0002822_catalepsy1.72866893
33MP0009780_abnormal_chondrocyte_physiolo1.72184721
34MP0000955_abnormal_spinal_cord1.64248727
35MP0005257_abnormal_intraocular_pressure1.63667869
36MP0005386_behavior/neurological_phenoty1.63596395
37MP0004924_abnormal_behavior1.63596395
38MP0004811_abnormal_neuron_physiology1.62213462
39MP0001529_abnormal_vocalization1.61060873
40MP0001958_emphysema1.56843220
41MP0003329_amyloid_beta_deposits1.55769868
42MP0005360_urolithiasis1.55723224
43MP0005645_abnormal_hypothalamus_physiol1.53891640
44MP0002882_abnormal_neuron_morphology1.50366933
45MP0001905_abnormal_dopamine_level1.50127802
46MP0003724_increased_susceptibility_to1.48964802
47MP0002557_abnormal_social/conspecific_i1.46380919
48MP0001501_abnormal_sleep_pattern1.46180521
49MP0004233_abnormal_muscle_weight1.46082362
50MP0003122_maternal_imprinting1.44706901
51MP0004858_abnormal_nervous_system1.43542079
52MP0000751_myopathy1.41815201
53MP0003283_abnormal_digestive_organ1.39753509
54MP0005058_abnormal_lysosome_morphology1.35966659
55MP0004142_abnormal_muscle_tone1.34775223
56MP0002066_abnormal_motor_capabilities/c1.34226224
57MP0005275_abnormal_skin_tensile1.30437203
58MP0006054_spinal_hemorrhage1.29502747
59MP0003634_abnormal_glial_cell1.26243828
60MP0004510_myositis1.25621979
61MP0008569_lethality_at_weaning1.25423715
62MP0006072_abnormal_retinal_apoptosis1.24534350
63MP0000343_altered_response_to1.24391372
64MP0003279_aneurysm1.20676324
65MP0001188_hyperpigmentation1.20529939
66MP0005623_abnormal_meninges_morphology1.19829938
67MP0002295_abnormal_pulmonary_circulatio1.19502331
68MP0005646_abnormal_pituitary_gland1.18784560
69MP0002909_abnormal_adrenal_gland1.17204199
70MP0002152_abnormal_brain_morphology1.15003645
71MP0003633_abnormal_nervous_system1.14353301
72MP0002332_abnormal_exercise_endurance1.13455973
73MP0006082_CNS_inflammation1.11130814
74MP0001502_abnormal_circadian_rhythm1.08812179
75MP0003631_nervous_system_phenotype1.05610903
76MP0010386_abnormal_urinary_bladder1.05367054
77MP0003300_gastrointestinal_ulcer1.04743234
78MP0004885_abnormal_endolymph1.04572631
79MP0003172_abnormal_lysosome_physiology1.02117081
80MP0005595_abnormal_vascular_smooth1.01836991
81MP0003195_calcinosis1.01678425
82MP0003075_altered_response_to1.00102608
83MP0003191_abnormal_cellular_cholesterol0.99832808
84MP0002752_abnormal_somatic_nervous0.99518708
85MP0004742_abnormal_vestibular_system0.99401662
86MP0000538_abnormal_urinary_bladder0.99149619
87MP0008004_abnormal_stomach_pH0.99136541
88MP0003787_abnormal_imprinting0.96609110
89MP0002837_dystrophic_cardiac_calcinosis0.96327387
90MP0003879_abnormal_hair_cell0.93454063
91MP0000920_abnormal_myelination0.93013670
92MP0001542_abnormal_bone_strength0.92742340
93MP0005248_abnormal_Harderian_gland0.92646539
94MP0005187_abnormal_penis_morphology0.91686069
95MP0000631_abnormal_neuroendocrine_gland0.90813249
96MP0009840_abnormal_foam_cell0.90568529
97MP0005551_abnormal_eye_electrophysiolog0.89819910
98MP0003091_abnormal_cell_migration0.89749604
99MP0000462_abnormal_digestive_system0.89281080
100MP0010030_abnormal_orbit_morphology0.87913042
101MP0002229_neurodegeneration0.86965607
102MP0002653_abnormal_ependyma_morphology0.86234998
103MP0000013_abnormal_adipose_tissue0.84893567
104MP0004043_abnormal_pH_regulation0.83288543
105MP0001879_abnormal_lymphatic_vessel0.82348312
106MP0003137_abnormal_impulse_conducting0.81873599
107MP0003861_abnormal_nervous_system0.81413725
108MP0003632_abnormal_nervous_system0.80932694
109MP0005394_taste/olfaction_phenotype0.80516874
110MP0005499_abnormal_olfactory_system0.80516874
111MP0003121_genomic_imprinting0.79492324
112MP0001963_abnormal_hearing_physiology0.79485497
113MP0001299_abnormal_eye_distance/0.79145997
114MP0002751_abnormal_autonomic_nervous0.79016045
115MP0004145_abnormal_muscle_electrophysio0.78842152
116MP0001943_abnormal_respiration0.77889045
117MP0004133_heterotaxia0.76721082
118MP0001756_abnormal_urination0.76337722
119MP0002896_abnormal_bone_mineralization0.74270647
120MP0003385_abnormal_body_wall0.74165482
121MP0009764_decreased_sensitivity_to0.73664677
122MP0010368_abnormal_lymphatic_system0.73455168
123MP0002139_abnormal_hepatobiliary_system0.73352910
124MP0002069_abnormal_eating/drinking_beha0.73138196
125MP0001485_abnormal_pinna_reflex0.71301468
126MP0002282_abnormal_trachea_morphology0.68255676
127MP0003119_abnormal_digestive_system0.67973235
128MP0003755_abnormal_palate_morphology0.67361015
129MP0000026_abnormal_inner_ear0.67047376
130MP0005253_abnormal_eye_physiology0.65964044
131MP0004484_altered_response_of0.63958192
132MP0003890_abnormal_embryonic-extraembry0.63338796
133MP0005195_abnormal_posterior_eye0.62605265
134MP0004134_abnormal_chest_morphology0.60980425
135MP0004085_abnormal_heartbeat0.60399214
136MP0000579_abnormal_nail_morphology0.60328955
137MP0003690_abnormal_glial_cell0.59635495
138MP0002090_abnormal_vision0.59188828
139MP0001177_atelectasis0.57251027
140MP0008789_abnormal_olfactory_epithelium0.56926035

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.93553259
2Myokymia (HP:0002411)4.83367476
3Atonic seizures (HP:0010819)4.52152605
4Epileptic encephalopathy (HP:0200134)3.98645774
5Focal seizures (HP:0007359)3.86512055
6Abnormality of liposaccharide metabolism (HP:0010968)3.74368816
7Abnormality of glycosphingolipid metabolism (HP:0004343)3.74368816
8Abnormality of glycolipid metabolism (HP:0010969)3.74368816
9Visual hallucinations (HP:0002367)3.52425326
10Absence seizures (HP:0002121)3.39791622
11Febrile seizures (HP:0002373)3.30420064
12Progressive cerebellar ataxia (HP:0002073)3.28708173
13Pheochromocytoma (HP:0002666)3.20509335
14Termporal pattern (HP:0011008)3.13427766
15Insidious onset (HP:0003587)3.13427766
16Disinhibition (HP:0000734)3.09604080
17Dialeptic seizures (HP:0011146)3.09068495
18Limb dystonia (HP:0002451)3.01345438
19Gait imbalance (HP:0002141)2.91893123
20Vacuolated lymphocytes (HP:0001922)2.91853932
21Action tremor (HP:0002345)2.89364242
22Diminished motivation (HP:0000745)2.87827132
23Apathy (HP:0000741)2.77302947
24Neuroendocrine neoplasm (HP:0100634)2.71263371
25Neurofibrillary tangles (HP:0002185)2.70479934
26Supranuclear gaze palsy (HP:0000605)2.68157975
27Narrow nasal bridge (HP:0000446)2.67422038
28Cerebral inclusion bodies (HP:0100314)2.62482523
29Ankle clonus (HP:0011448)2.58168007
30Abnormality of the labia minora (HP:0012880)2.57900294
31Generalized tonic-clonic seizures (HP:0002069)2.56404721
32Akinesia (HP:0002304)2.51926225
33Polyphagia (HP:0002591)2.51098645
34Amblyopia (HP:0000646)2.50685917
35Alacrima (HP:0000522)2.50304096
36Broad-based gait (HP:0002136)2.47908405
37Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.47507622
38Congenital primary aphakia (HP:0007707)2.44160895
39Dysdiadochokinesis (HP:0002075)2.43794531
40Neuronal loss in central nervous system (HP:0002529)2.39776416
41Concave nail (HP:0001598)2.39241400
42Hyperventilation (HP:0002883)2.39225620
43Abnormal eating behavior (HP:0100738)2.38825158
44Dysostosis multiplex (HP:0000943)2.37983083
45Abnormality of the corticospinal tract (HP:0002492)2.34560610
46Abnormality of mucopolysaccharide metabolism (HP:0011020)2.34524309
47Abnormality of polysaccharide metabolism (HP:0011012)2.34524309
48Abnormality of glycosaminoglycan metabolism (HP:0004371)2.34524309
49Hyperthyroidism (HP:0000836)2.34287270
50Anteriorly placed anus (HP:0001545)2.32992367
51Inappropriate behavior (HP:0000719)2.32739772
52Tetraparesis (HP:0002273)2.32586657
53Fetal akinesia sequence (HP:0001989)2.32568471
54Papillary thyroid carcinoma (HP:0002895)2.30887887
55Dysmetria (HP:0001310)2.30859559
56Thickened helices (HP:0000391)2.29873416
57Mutism (HP:0002300)2.28535504
58Amyotrophic lateral sclerosis (HP:0007354)2.27605617
59Annular pancreas (HP:0001734)2.27353574
60Mucopolysacchariduria (HP:0008155)2.26118057
61Urinary glycosaminoglycan excretion (HP:0003541)2.26118057
62Cortical dysplasia (HP:0002539)2.26017437
63Clumsiness (HP:0002312)2.25089824
64Medial flaring of the eyebrow (HP:0010747)2.24900508
65Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.24797962
66Specific learning disability (HP:0001328)2.24473024
67Nephrogenic diabetes insipidus (HP:0009806)2.20677590
68Failure to thrive in infancy (HP:0001531)2.18509314
69Nuclear cataract (HP:0100018)2.17539574
70Epileptiform EEG discharges (HP:0011182)2.16561497
71Progressive inability to walk (HP:0002505)2.16148189
72Coronal craniosynostosis (HP:0004440)2.15911567
73Hypercortisolism (HP:0001578)2.15274382
74Degeneration of the lateral corticospinal tracts (HP:0002314)2.14830279
75Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.14830279
76Loss of speech (HP:0002371)2.14302024
77Wrist flexion contracture (HP:0001239)2.12142797
78Ulnar claw (HP:0001178)2.11853219
79Facial hemangioma (HP:0000329)2.11762779
80Vaginal atresia (HP:0000148)2.10566728
81Excessive salivation (HP:0003781)2.09968441
82Drooling (HP:0002307)2.09968441
83Turricephaly (HP:0000262)2.09594446
84Genital tract atresia (HP:0001827)2.08802444
85Hammertoe (HP:0001765)2.07679880
86EEG with generalized epileptiform discharges (HP:0011198)2.06903847
87Pachygyria (HP:0001302)2.02523045
88Hand muscle atrophy (HP:0009130)2.00125830
89Hip dysplasia (HP:0001385)1.97909818
90Hypsarrhythmia (HP:0002521)1.96463623
91Abnormal hair whorl (HP:0010721)1.95594752
92Follicular hyperkeratosis (HP:0007502)1.94105173
93Torticollis (HP:0000473)1.94054439
94Hematochezia (HP:0002573)1.93201662
95Sensory axonal neuropathy (HP:0003390)1.93023685
96Anxiety (HP:0000739)1.92242881
97Decreased lacrimation (HP:0000633)1.90056504
98Choroideremia (HP:0001139)1.89999575
99Absent speech (HP:0001344)1.89668125
100Truncal ataxia (HP:0002078)1.88063151
101Depression (HP:0000716)1.87447892
102Mitral stenosis (HP:0001718)1.86425267
103Neoplasm of the heart (HP:0100544)1.85938061
104Megalencephaly (HP:0001355)1.84936135
105Orthostatic hypotension (HP:0001278)1.84727643
106Aqueductal stenosis (HP:0002410)1.84627535
107Poor suck (HP:0002033)1.84059582
108Genetic anticipation (HP:0003743)1.83619159
109Hypoventilation (HP:0002791)1.83325096
110Spastic tetraplegia (HP:0002510)1.82572833
111Intention tremor (HP:0002080)1.82185258
112Urinary bladder sphincter dysfunction (HP:0002839)1.81722350
113Spastic gait (HP:0002064)1.81465749
114Diminished movement (HP:0002374)1.81444263
115Lower limb muscle weakness (HP:0007340)1.79193004
116Hemiplegia (HP:0002301)1.76694631
117Scanning speech (HP:0002168)1.75570948
118Abnormality of salivation (HP:0100755)1.75425374
119Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.75278291
120Poor coordination (HP:0002370)1.75136431
121Hypoplasia of the fovea (HP:0007750)1.74885727
122Aplasia/Hypoplasia of the fovea (HP:0008060)1.74885727
123Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.74719535
124Neoplasm of the peripheral nervous system (HP:0100007)1.74285845
125Postural tremor (HP:0002174)1.72130757
126Focal dystonia (HP:0004373)1.71797882
127Urinary urgency (HP:0000012)1.71415435
128Aplasia involving bones of the extremities (HP:0009825)1.71108155
129Aplasia involving bones of the upper limbs (HP:0009823)1.71108155
130Aplasia of the phalanges of the hand (HP:0009802)1.71108155
131Abnormality of the aortic arch (HP:0012303)1.70577825
132Gait ataxia (HP:0002066)1.70008902
133Systemic lupus erythematosus (HP:0002725)1.69982592
134Abnormality of binocular vision (HP:0011514)1.69518775
135Diplopia (HP:0000651)1.69518775
136Gaze-evoked nystagmus (HP:0000640)1.69375527
137Increased CSF protein (HP:0002922)1.69319156
138Hemiparesis (HP:0001269)1.68817924
139Hypoplasia of the corpus callosum (HP:0002079)1.68464386
140Vascular tortuosity (HP:0004948)1.67846639
141Impaired vibration sensation in the lower limbs (HP:0002166)1.67569440
142Abnormality of the lower motor neuron (HP:0002366)1.67280390
143Paraplegia (HP:0010550)1.66707511
144Agitation (HP:0000713)1.66482664
145Generalized myoclonic seizures (HP:0002123)1.66214267
146Shoulder girdle muscle weakness (HP:0003547)1.65677895
147Short chin (HP:0000331)1.63160299
148Rapidly progressive (HP:0003678)1.62540903
149Aplasia/Hypoplasia of the lens (HP:0008063)1.62496640
150Rectal fistula (HP:0100590)1.62481270

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.18203675
2CASK3.04785213
3MAP3K92.82718662
4NTRK32.76224406
5ICK2.49668523
6DDR22.46040337
7MAP3K42.41056259
8MAP3K62.32910819
9UHMK12.25637258
10TYRO32.24874706
11FGR2.19776708
12MINK12.12792947
13EPHA42.12135095
14MAP2K71.92971755
15MAP3K121.89936186
16DAPK11.77783921
17PRPF4B1.75399461
18EPHA31.75111220
19NTRK21.73248428
20PHKG21.71463741
21PHKG11.71463741
22PLK21.65730459
23TIE11.64959284
24PAK61.59597075
25TRIM281.58116996
26TESK11.56073687
27KSR11.55027389
28LATS21.50602669
29AKT31.48208520
30KSR21.47051195
31MAPK131.43855012
32MAPK151.39187535
33NTRK11.38765149
34MAP4K21.37392348
35OXSR11.33371493
36MAP2K41.32978643
37PINK11.32360914
38CDK191.32257644
39BCR1.30698752
40DYRK21.27830416
41TGFBR21.22108098
42CDK51.21232609
43LIMK11.18864447
44STK391.18860180
45GRK51.18612600
46DAPK21.17544143
47CAMK2A1.14164097
48CAMK2B1.13776942
49ARAF1.12272033
50MATK1.06555550
51CDK141.02515236
52TAOK11.01805216
53ERBB31.01431736
54MAP3K110.99160621
55SGK20.96890354
56CDK180.95159651
57RIPK10.94966664
58PRKD20.93116461
59CSNK1G20.92394339
60CDK150.91100769
61EPHB10.90265480
62SIK30.85125256
63ADRBK20.82753004
64YES10.82598952
65MOS0.82395639
66PAK30.82008643
67FER0.81885020
68PNCK0.81530562
69CDK11A0.78293649
70MAP3K20.78143847
71PRKCG0.77498767
72IRAK20.77041132
73BMPR1B0.76375479
74BMX0.76322962
75CAMK2D0.76085738
76PRKD30.72539123
77CSNK1G30.72496797
78NME10.72322373
79STK38L0.72254039
80RIPK40.72141463
81SGK4940.70079002
82SGK2230.70079002
83PRKCE0.67229508
84PTK2B0.66451924
85PDGFRA0.66391686
86RAF10.63689895
87FGFR20.63553753
88MAP3K50.62796746
89MYLK0.61298238
90CSNK1G10.59668558
91PKN20.58828780
92CAMK2G0.57926648
93PKN10.57475864
94ROCK20.57443672
95SGK30.56654853
96STK110.56193491
97CDC42BPA0.54901155
98PRKG20.54239484
99DYRK1A0.53548348
100SGK10.52387953
101SIK20.52143666
102BMPR20.52011646
103DYRK1B0.51863302
104MARK20.51449466
105PRKCZ0.50728792
106CSNK1A1L0.50470985
107TGFBR10.50445436
108STK380.49969419
109PRKG10.49487402
110ADRBK10.48450569
111RET0.47066748
112PIM20.47022967
113ERBB40.45767478
114TAOK30.45647500
115MAPKAPK50.44912789
116CAMKK20.44783539
117GSK3A0.44453847
118FES0.43343338
119NEK90.42492775
120ABL20.40836790
121CAMKK10.40584309
122PRKD10.40465475
123WNK30.40243120
124ROCK10.39772862
125MAP2K10.39653496
126EPHB20.39343204
127WNK40.38931901
128IRAK10.38368681
129TNIK0.36657774
130MAPK100.32858713
131GRK70.32847705

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.06525024
2Nicotine addiction_Homo sapiens_hsa050333.02283567
3Olfactory transduction_Homo sapiens_hsa047402.32888033
4Collecting duct acid secretion_Homo sapiens_hsa049662.32531689
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.30739525
6GABAergic synapse_Homo sapiens_hsa047272.26484777
7Glutamatergic synapse_Homo sapiens_hsa047242.05769541
8Circadian entrainment_Homo sapiens_hsa047131.99589290
9Long-term potentiation_Homo sapiens_hsa047201.99016307
10Dopaminergic synapse_Homo sapiens_hsa047281.98734389
11Morphine addiction_Homo sapiens_hsa050321.97368928
12Long-term depression_Homo sapiens_hsa047301.88766980
13Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.85615725
14Amphetamine addiction_Homo sapiens_hsa050311.85154847
15Serotonergic synapse_Homo sapiens_hsa047261.79665693
16Vibrio cholerae infection_Homo sapiens_hsa051101.72674367
17Axon guidance_Homo sapiens_hsa043601.62974028
18Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.61415322
19Gap junction_Homo sapiens_hsa045401.60879339
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.59631232
21Salivary secretion_Homo sapiens_hsa049701.58511489
22Oxidative phosphorylation_Homo sapiens_hsa001901.54063085
23Cholinergic synapse_Homo sapiens_hsa047251.53575744
24Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.52589857
25Taste transduction_Homo sapiens_hsa047421.50322100
26Fatty acid biosynthesis_Homo sapiens_hsa000611.49631479
27Lysosome_Homo sapiens_hsa041421.49007941
28Glycosaminoglycan degradation_Homo sapiens_hsa005311.47863205
29Renin secretion_Homo sapiens_hsa049241.45418543
30Gastric acid secretion_Homo sapiens_hsa049711.43798942
31GnRH signaling pathway_Homo sapiens_hsa049121.37985735
32Insulin secretion_Homo sapiens_hsa049111.36311832
33Oxytocin signaling pathway_Homo sapiens_hsa049211.32320170
34Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.30982232
35Cocaine addiction_Homo sapiens_hsa050301.27505513
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.26847616
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.25262448
38ErbB signaling pathway_Homo sapiens_hsa040121.23395433
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19401469
40Alzheimers disease_Homo sapiens_hsa050101.18654604
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.17138041
42Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.16454680
43Cardiac muscle contraction_Homo sapiens_hsa042601.15301912
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.13957473
45Dorso-ventral axis formation_Homo sapiens_hsa043201.13257522
46Parkinsons disease_Homo sapiens_hsa050121.10455160
47Aldosterone synthesis and secretion_Homo sapiens_hsa049251.09011656
48Pertussis_Homo sapiens_hsa051331.08992069
49Calcium signaling pathway_Homo sapiens_hsa040201.07718560
50Oocyte meiosis_Homo sapiens_hsa041141.06403253
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.02817133
52Estrogen signaling pathway_Homo sapiens_hsa049151.01951863
53Other glycan degradation_Homo sapiens_hsa005110.99990008
54Sphingolipid metabolism_Homo sapiens_hsa006000.98157752
55Melanogenesis_Homo sapiens_hsa049160.95690447
56Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.94517214
57Circadian rhythm_Homo sapiens_hsa047100.94477485
58Phototransduction_Homo sapiens_hsa047440.93644393
59Glioma_Homo sapiens_hsa052140.90964224
60Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.89108301
61Hedgehog signaling pathway_Homo sapiens_hsa043400.88562527
62cAMP signaling pathway_Homo sapiens_hsa040240.88392710
63VEGF signaling pathway_Homo sapiens_hsa043700.85156152
64* Phagosome_Homo sapiens_hsa041450.81782890
65Sphingolipid signaling pathway_Homo sapiens_hsa040710.81046003
66Choline metabolism in cancer_Homo sapiens_hsa052310.80741042
67mTOR signaling pathway_Homo sapiens_hsa041500.80561350
68Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.79571709
69Ras signaling pathway_Homo sapiens_hsa040140.79488160
70Vascular smooth muscle contraction_Homo sapiens_hsa042700.79085124
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.77542369
72Renal cell carcinoma_Homo sapiens_hsa052110.76578003
73Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.76083086
74Hippo signaling pathway_Homo sapiens_hsa043900.75730129
75Legionellosis_Homo sapiens_hsa051340.73821221
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73820444
77Regulation of autophagy_Homo sapiens_hsa041400.73422854
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73324290
79Wnt signaling pathway_Homo sapiens_hsa043100.73244544
80PPAR signaling pathway_Homo sapiens_hsa033200.73175305
81MAPK signaling pathway_Homo sapiens_hsa040100.72151095
82Huntingtons disease_Homo sapiens_hsa050160.71307932
83Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70922548
84Rheumatoid arthritis_Homo sapiens_hsa053230.70444121
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70298612
86Tight junction_Homo sapiens_hsa045300.70187364
87Endocytosis_Homo sapiens_hsa041440.68947134
88Tuberculosis_Homo sapiens_hsa051520.68808681
89AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.67634917
90Phosphatidylinositol signaling system_Homo sapiens_hsa040700.66487424
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65840171
92Dilated cardiomyopathy_Homo sapiens_hsa054140.64459935
93Amoebiasis_Homo sapiens_hsa051460.63675458
94Rap1 signaling pathway_Homo sapiens_hsa040150.63375347
95Colorectal cancer_Homo sapiens_hsa052100.61814004
96Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60738350
97Toll-like receptor signaling pathway_Homo sapiens_hsa046200.60315950
98Phospholipase D signaling pathway_Homo sapiens_hsa040720.59804832
99Malaria_Homo sapiens_hsa051440.58767930
100Type II diabetes mellitus_Homo sapiens_hsa049300.56870519
101Ether lipid metabolism_Homo sapiens_hsa005650.55576737
102Primary bile acid biosynthesis_Homo sapiens_hsa001200.55267565
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.54715684
104Osteoclast differentiation_Homo sapiens_hsa043800.54472005
105Pancreatic secretion_Homo sapiens_hsa049720.54329673
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54118904
107TNF signaling pathway_Homo sapiens_hsa046680.52801527
108Chemokine signaling pathway_Homo sapiens_hsa040620.52148233
109Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51939068
110Endometrial cancer_Homo sapiens_hsa052130.51191940
111Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50709501
112Steroid biosynthesis_Homo sapiens_hsa001000.50012123
113Mineral absorption_Homo sapiens_hsa049780.49353838
114Ovarian steroidogenesis_Homo sapiens_hsa049130.48865731
115Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48627920
116Butanoate metabolism_Homo sapiens_hsa006500.46912012
117Protein digestion and absorption_Homo sapiens_hsa049740.46370459
118Staphylococcus aureus infection_Homo sapiens_hsa051500.46045902
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43935116
120Thyroid hormone synthesis_Homo sapiens_hsa049180.43773704
121Salmonella infection_Homo sapiens_hsa051320.41646439
122Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.41239941
123Shigellosis_Homo sapiens_hsa051310.40950371
124Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.40878881
125Neurotrophin signaling pathway_Homo sapiens_hsa047220.40874269
126Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.40079387
127Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39697744
128Prion diseases_Homo sapiens_hsa050200.39547858
129Melanoma_Homo sapiens_hsa052180.38213683
130beta-Alanine metabolism_Homo sapiens_hsa004100.37804101
131Protein export_Homo sapiens_hsa030600.37521365
132African trypanosomiasis_Homo sapiens_hsa051430.37323553
133Focal adhesion_Homo sapiens_hsa045100.37293954
134Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37121690

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