

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.22844984 |
| 2 | negative regulation of cell killing (GO:0031342) | 5.89768503 |
| 3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.89768503 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 5.26207821 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 5.26207821 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.26207821 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.26207821 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.26207821 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.26207821 |
| 10 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.81028759 |
| 11 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.63994072 |
| 12 | regulation of gamma-delta T cell activation (GO:0046643) | 4.59574870 |
| 13 | leukocyte aggregation (GO:0070486) | 4.53111995 |
| 14 | negative thymic T cell selection (GO:0045060) | 4.47989054 |
| 15 | cellular extravasation (GO:0045123) | 4.46636638 |
| 16 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.43756874 |
| 17 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.43076690 |
| 18 | detection of other organism (GO:0098543) | 4.34512705 |
| 19 | negative T cell selection (GO:0043383) | 4.33129541 |
| 20 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.21293288 |
| 21 | response to muramyl dipeptide (GO:0032495) | 4.20511850 |
| 22 | macrophage activation involved in immune response (GO:0002281) | 4.16339651 |
| 23 | response to peptidoglycan (GO:0032494) | 4.15287428 |
| 24 | positive thymic T cell selection (GO:0045059) | 4.11678943 |
| 25 | response to interleukin-15 (GO:0070672) | 4.11170273 |
| 26 | detection of bacterium (GO:0016045) | 4.09343253 |
| 27 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.08531287 |
| 28 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.06843349 |
| 29 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.01028545 |
| 30 | detection of molecule of bacterial origin (GO:0032490) | 3.88265686 |
| 31 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.87994875 |
| 32 | B cell receptor signaling pathway (GO:0050853) | 3.84907126 |
| 33 | germinal center formation (GO:0002467) | 3.82906218 |
| 34 | activated T cell proliferation (GO:0050798) | 3.82886838 |
| 35 | negative regulation of T cell mediated immunity (GO:0002710) | 3.79239646 |
| 36 | tolerance induction (GO:0002507) | 3.77467026 |
| 37 | positive T cell selection (GO:0043368) | 3.75776392 |
| 38 | detection of external biotic stimulus (GO:0098581) | 3.74721814 |
| 39 | negative regulation of interleukin-12 production (GO:0032695) | 3.70872568 |
| 40 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.69326821 |
| 41 | neutrophil mediated immunity (GO:0002446) | 3.67033513 |
| 42 | neutrophil activation involved in immune response (GO:0002283) | 3.66728084 |
| 43 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.64332027 |
| 44 | T cell selection (GO:0045058) | 3.62196957 |
| 45 | thymic T cell selection (GO:0045061) | 3.60914001 |
| 46 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.60184125 |
| 47 | response to host immune response (GO:0052572) | 3.60184125 |
| 48 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.53335593 |
| 49 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.45979766 |
| 50 | respiratory burst (GO:0045730) | 3.43457797 |
| 51 | histone H3-K36 demethylation (GO:0070544) | 3.39339852 |
| 52 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.38323039 |
| 53 | T cell migration (GO:0072678) | 3.36454775 |
| 54 | neutrophil activation (GO:0042119) | 3.35984829 |
| 55 | detection of biotic stimulus (GO:0009595) | 3.35821692 |
| 56 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.33750003 |
| 57 | response to host (GO:0075136) | 3.33750003 |
| 58 | response to host defenses (GO:0052200) | 3.33750003 |
| 59 | cellular response to interleukin-15 (GO:0071350) | 3.26404707 |
| 60 | positive regulation of B cell differentiation (GO:0045579) | 3.25644002 |
| 61 | regulation of B cell differentiation (GO:0045577) | 3.20645373 |
| 62 | microglial cell activation (GO:0001774) | 3.20156882 |
| 63 | interferon-gamma production (GO:0032609) | 3.19980585 |
| 64 | myeloid leukocyte mediated immunity (GO:0002444) | 3.19374161 |
| 65 | defense response to protozoan (GO:0042832) | 3.19244386 |
| 66 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.19050766 |
| 67 | macrophage activation (GO:0042116) | 3.15094465 |
| 68 | regulation of T cell tolerance induction (GO:0002664) | 3.12611059 |
| 69 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.09827200 |
| 70 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.08083897 |
| 71 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.07850961 |
| 72 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.07529851 |
| 73 | myeloid cell activation involved in immune response (GO:0002275) | 3.05054084 |
| 74 | positive regulation of granulocyte differentiation (GO:0030854) | 3.03932724 |
| 75 | regulation of mast cell degranulation (GO:0043304) | 3.02880203 |
| 76 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.02250671 |
| 77 | regulation of tolerance induction (GO:0002643) | 3.01330905 |
| 78 | granulocyte activation (GO:0036230) | 3.00066254 |
| 79 | negative regulation of innate immune response (GO:0045824) | 2.95536985 |
| 80 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.93091959 |
| 81 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.91191490 |
| 82 | regulation of mast cell activation (GO:0033003) | 2.87099464 |
| 83 | immunoglobulin mediated immune response (GO:0016064) | 2.84354425 |
| 84 | response to protozoan (GO:0001562) | 2.82909846 |
| 85 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.82494620 |
| 86 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.82473687 |
| 87 | positive regulation of mast cell activation (GO:0033005) | 2.78190563 |
| 88 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.77822860 |
| 89 | regulation of ARF protein signal transduction (GO:0032012) | 2.77511701 |
| 90 | regulation of leukocyte degranulation (GO:0043300) | 2.76641382 |
| 91 | negative regulation of type 2 immune response (GO:0002829) | 2.76176269 |
| 92 | mannose metabolic process (GO:0006013) | 2.76101215 |
| 93 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.75144628 |
| 94 | negative regulation of B cell mediated immunity (GO:0002713) | 2.75144628 |
| 95 | cellular response to type I interferon (GO:0071357) | 2.74515297 |
| 96 | type I interferon signaling pathway (GO:0060337) | 2.74515297 |
| 97 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.74321445 |
| 98 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.74321445 |
| 99 | response to type I interferon (GO:0034340) | 2.73633076 |
| 100 | negative regulation of interleukin-6 production (GO:0032715) | 2.72159926 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.38439092 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.29591506 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.47751244 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.43672990 |
| 5 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.32287473 |
| 6 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.04940996 |
| 7 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.99252839 |
| 8 | MYC_22102868_ChIP-Seq_BL_Human | 2.97611201 |
| 9 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.95182846 |
| 10 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.91638208 |
| 11 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.83276882 |
| 12 | MAF_26560356_Chip-Seq_TH1_Human | 2.62104674 |
| 13 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.54999044 |
| 14 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.54504928 |
| 15 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.45863578 |
| 16 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.45792640 |
| 17 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.44911510 |
| 18 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.44889218 |
| 19 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.43626288 |
| 20 | UTX_26944678_Chip-Seq_JUKART_Human | 2.43241746 |
| 21 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.42409796 |
| 22 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.34612499 |
| 23 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.29844452 |
| 24 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.27563350 |
| 25 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.26491192 |
| 26 | SPI1_23127762_ChIP-Seq_K562_Human | 2.22399622 |
| 27 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.18662734 |
| 28 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.15979577 |
| 29 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.15691084 |
| 30 | MYB_26560356_Chip-Seq_TH2_Human | 2.15554991 |
| 31 | MAF_26560356_Chip-Seq_TH2_Human | 2.12050332 |
| 32 | MYB_26560356_Chip-Seq_TH1_Human | 2.07129085 |
| 33 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.06885018 |
| 34 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.05756646 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.03678751 |
| 36 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.01069387 |
| 37 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.95612635 |
| 38 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.94543632 |
| 39 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.93961380 |
| 40 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.91206208 |
| 41 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.90675447 |
| 42 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.79949275 |
| 43 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.77341104 |
| 44 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.76354597 |
| 45 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.75081016 |
| 46 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.67362281 |
| 47 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.66490381 |
| 48 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.58448877 |
| 49 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.55776018 |
| 50 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.55098682 |
| 51 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.53677824 |
| 52 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.51875781 |
| 53 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.51179304 |
| 54 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.50202565 |
| 55 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.35747860 |
| 56 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.34294141 |
| 57 | KDM2B_26808549_Chip-Seq_K562_Human | 1.29434845 |
| 58 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.28563542 |
| 59 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.25614199 |
| 60 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.25392272 |
| 61 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.25014578 |
| 62 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.24201632 |
| 63 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.23670341 |
| 64 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.22675691 |
| 65 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.22605564 |
| 66 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.20411068 |
| 67 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.19544564 |
| 68 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.18376518 |
| 69 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16922260 |
| 70 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.16756296 |
| 71 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.15874741 |
| 72 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14992043 |
| 73 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.14353223 |
| 74 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.13227666 |
| 75 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.08864462 |
| 76 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06945020 |
| 77 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06208760 |
| 78 | GATA3_26560356_Chip-Seq_TH2_Human | 1.05518388 |
| 79 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.04322894 |
| 80 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01923193 |
| 81 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01268782 |
| 82 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.01241644 |
| 83 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00357341 |
| 84 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.99304595 |
| 85 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.98607195 |
| 86 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.98004278 |
| 87 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.96804492 |
| 88 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.96738647 |
| 89 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.96194210 |
| 90 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95907867 |
| 91 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.95305350 |
| 92 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.94872849 |
| 93 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.94630164 |
| 94 | GATA1_19941826_ChIP-Seq_K562_Human | 0.94499772 |
| 95 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.94038842 |
| 96 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.93716739 |
| 97 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.93632694 |
| 98 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.93281190 |
| 99 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.92618826 |
| 100 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.91328896 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003436_decreased_susceptibility_to | 4.30413831 |
| 2 | MP0003724_increased_susceptibility_to | 4.07358266 |
| 3 | MP0003303_peritoneal_inflammation | 3.68024806 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.16521932 |
| 5 | MP0001800_abnormal_humoral_immune | 2.97585222 |
| 6 | MP0003172_abnormal_lysosome_physiology | 2.89738512 |
| 7 | MP0005451_abnormal_body_composition | 2.79663315 |
| 8 | MP0002419_abnormal_innate_immunity | 2.78997494 |
| 9 | MP0003763_abnormal_thymus_physiology | 2.77856592 |
| 10 | MP0000685_abnormal_immune_system | 2.70691304 |
| 11 | MP0005671_abnormal_response_to | 2.66821788 |
| 12 | MP0005000_abnormal_immune_tolerance | 2.64220065 |
| 13 | MP0008260_abnormal_autophagy | 2.61056409 |
| 14 | MP0001790_abnormal_immune_system | 2.60135615 |
| 15 | MP0005387_immune_system_phenotype | 2.60135615 |
| 16 | MP0005025_abnormal_response_to | 2.59827345 |
| 17 | MP0002723_abnormal_immune_serum | 2.50433709 |
| 18 | MP0002420_abnormal_adaptive_immunity | 2.42783074 |
| 19 | MP0001819_abnormal_immune_cell | 2.39653230 |
| 20 | MP0002452_abnormal_antigen_presenting | 2.31559472 |
| 21 | MP0003300_gastrointestinal_ulcer | 2.22918720 |
| 22 | MP0009278_abnormal_bone_marrow | 2.11833068 |
| 23 | MP0009785_altered_susceptibility_to | 2.01351405 |
| 24 | MP0002405_respiratory_system_inflammati | 1.98876073 |
| 25 | MP0002398_abnormal_bone_marrow | 1.97876980 |
| 26 | MP0003191_abnormal_cellular_cholesterol | 1.94766831 |
| 27 | MP0002132_abnormal_respiratory_system | 1.92925207 |
| 28 | MP0000716_abnormal_immune_system | 1.91930975 |
| 29 | MP0002396_abnormal_hematopoietic_system | 1.82703538 |
| 30 | MP0006082_CNS_inflammation | 1.79473808 |
| 31 | MP0001533_abnormal_skeleton_physiology | 1.77643021 |
| 32 | MP0005464_abnormal_platelet_physiology | 1.75986066 |
| 33 | MP0004510_myositis | 1.72602616 |
| 34 | MP0004947_skin_inflammation | 1.68125153 |
| 35 | MP0000703_abnormal_thymus_morphology | 1.67154842 |
| 36 | MP0000689_abnormal_spleen_morphology | 1.63511437 |
| 37 | MP0002722_abnormal_immune_system | 1.63265576 |
| 38 | MP0003122_maternal_imprinting | 1.63055216 |
| 39 | MP0004381_abnormal_hair_follicle | 1.62758608 |
| 40 | MP0009333_abnormal_splenocyte_physiolog | 1.60082431 |
| 41 | MP0003866_abnormal_defecation | 1.55003387 |
| 42 | MP0003828_pulmonary_edema | 1.50045406 |
| 43 | MP0002429_abnormal_blood_cell | 1.45193701 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.41892623 |
| 45 | MP0002009_preneoplasia | 1.40886865 |
| 46 | MP0003690_abnormal_glial_cell | 1.40839470 |
| 47 | MP0010155_abnormal_intestine_physiology | 1.40383730 |
| 48 | MP0002148_abnormal_hypersensitivity_rea | 1.33671736 |
| 49 | MP0001986_abnormal_taste_sensitivity | 1.32796386 |
| 50 | MP0004883_abnormal_blood_vessel | 1.32186143 |
| 51 | MP0000465_gastrointestinal_hemorrhage | 1.31992258 |
| 52 | MP0002277_abnormal_respiratory_mucosa | 1.26038186 |
| 53 | MP0001851_eye_inflammation | 1.23267548 |
| 54 | MP0008469_abnormal_protein_level | 1.22922436 |
| 55 | MP0005310_abnormal_salivary_gland | 1.22057772 |
| 56 | MP0005397_hematopoietic_system_phenotyp | 1.20645357 |
| 57 | MP0001545_abnormal_hematopoietic_system | 1.20645357 |
| 58 | MP0003221_abnormal_cardiomyocyte_apopto | 1.18524355 |
| 59 | MP0002933_joint_inflammation | 1.10906890 |
| 60 | MP0004130_abnormal_muscle_cell | 1.07803950 |
| 61 | MP0002166_altered_tumor_susceptibility | 1.06862220 |
| 62 | MP0005058_abnormal_lysosome_morphology | 1.06038511 |
| 63 | MP0001873_stomach_inflammation | 1.05807117 |
| 64 | MP0000858_altered_metastatic_potential | 1.05668287 |
| 65 | MP0002998_abnormal_bone_remodeling | 1.04848743 |
| 66 | MP0003787_abnormal_imprinting | 1.03771061 |
| 67 | MP0005076_abnormal_cell_differentiation | 0.99560380 |
| 68 | MP0002822_catalepsy | 0.94371226 |
| 69 | MP0003183_abnormal_peptide_metabolism | 0.93234368 |
| 70 | MP0000604_amyloidosis | 0.89475865 |
| 71 | MP0009764_decreased_sensitivity_to | 0.84320406 |
| 72 | MP0008961_abnormal_basal_metabolism | 0.82339987 |
| 73 | MP0004808_abnormal_hematopoietic_stem | 0.77259464 |
| 74 | MP0003656_abnormal_erythrocyte_physiolo | 0.76056508 |
| 75 | MP0001853_heart_inflammation | 0.74861444 |
| 76 | MP0003075_altered_response_to | 0.72888751 |
| 77 | MP0001663_abnormal_digestive_system | 0.72294463 |
| 78 | MP0005164_abnormal_response_to | 0.71162306 |
| 79 | MP0002928_abnormal_bile_duct | 0.68143918 |
| 80 | MP0008569_lethality_at_weaning | 0.64695977 |
| 81 | MP0009763_increased_sensitivity_to | 0.61608295 |
| 82 | MP0003329_amyloid_beta_deposits | 0.61551940 |
| 83 | MP0005075_abnormal_melanosome_morpholog | 0.61525179 |
| 84 | MP0009840_abnormal_foam_cell | 0.60829342 |
| 85 | MP0002006_tumorigenesis | 0.58287273 |
| 86 | MP0000249_abnormal_blood_vessel | 0.57627654 |
| 87 | MP0005167_abnormal_blood-brain_barrier | 0.57289708 |
| 88 | MP0003121_genomic_imprinting | 0.55925538 |
| 89 | MP0000609_abnormal_liver_physiology | 0.54626559 |
| 90 | MP0003091_abnormal_cell_migration | 0.53830517 |
| 91 | MP0001348_abnormal_lacrimal_gland | 0.53798879 |
| 92 | MP0002693_abnormal_pancreas_physiology | 0.52253509 |
| 93 | MP0008874_decreased_physiological_sensi | 0.51999936 |
| 94 | MP0000920_abnormal_myelination | 0.51980023 |
| 95 | MP0009115_abnormal_fat_cell | 0.51062307 |
| 96 | MP0003045_fibrosis | 0.48596734 |
| 97 | MP0005377_hearing/vestibular/ear_phenot | 0.48517089 |
| 98 | MP0003878_abnormal_ear_physiology | 0.48517089 |
| 99 | MP0002332_abnormal_exercise_endurance | 0.48345718 |
| 100 | MP0005360_urolithiasis | 0.47787115 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 6.19659678 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 5.28629894 |
| 3 | Myositis (HP:0100614) | 5.12650079 |
| 4 | Recurrent abscess formation (HP:0002722) | 5.02038955 |
| 5 | Retrobulbar optic neuritis (HP:0100654) | 4.87586264 |
| 6 | Optic neuritis (HP:0100653) | 4.87586264 |
| 7 | Orchitis (HP:0100796) | 4.77657275 |
| 8 | Abnormality of macrophages (HP:0004311) | 4.45101368 |
| 9 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.39028109 |
| 10 | Recurrent fungal infections (HP:0002841) | 4.18537906 |
| 11 | Stomatitis (HP:0010280) | 4.14617278 |
| 12 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.10481875 |
| 13 | Gastrointestinal infarctions (HP:0005244) | 4.07666043 |
| 14 | Mediastinal lymphadenopathy (HP:0100721) | 3.85381658 |
| 15 | Meningitis (HP:0001287) | 3.81600865 |
| 16 | Recurrent skin infections (HP:0001581) | 3.71850292 |
| 17 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.70711728 |
| 18 | Recurrent cutaneous fungal infections (HP:0011370) | 3.59481376 |
| 19 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.59481376 |
| 20 | Encephalitis (HP:0002383) | 3.58464282 |
| 21 | Pustule (HP:0200039) | 3.55698355 |
| 22 | Panhypogammaglobulinemia (HP:0003139) | 3.52409475 |
| 23 | Increased IgE level (HP:0003212) | 3.46966358 |
| 24 | Vasculitis (HP:0002633) | 3.35445378 |
| 25 | Chronic obstructive pulmonary disease (HP:0006510) | 3.31999444 |
| 26 | Obstructive lung disease (HP:0006536) | 3.31999444 |
| 27 | Keratoconjunctivitis sicca (HP:0001097) | 3.29494263 |
| 28 | Prolonged bleeding time (HP:0003010) | 3.22888366 |
| 29 | Colitis (HP:0002583) | 3.15047237 |
| 30 | Inflammation of the large intestine (HP:0002037) | 3.07567943 |
| 31 | Gastrointestinal inflammation (HP:0004386) | 3.05074474 |
| 32 | Spontaneous hematomas (HP:0007420) | 3.01969694 |
| 33 | Keratoconjunctivitis (HP:0001096) | 2.96508342 |
| 34 | Gingival bleeding (HP:0000225) | 2.93038402 |
| 35 | Gingivitis (HP:0000230) | 2.91485507 |
| 36 | Deep venous thrombosis (HP:0002625) | 2.86500387 |
| 37 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.85196831 |
| 38 | Chest pain (HP:0100749) | 2.85157015 |
| 39 | Recurrent viral infections (HP:0004429) | 2.78570833 |
| 40 | Episodic fever (HP:0001954) | 2.77063409 |
| 41 | T lymphocytopenia (HP:0005403) | 2.76158887 |
| 42 | Pulmonary embolism (HP:0002204) | 2.69124689 |
| 43 | Hemoptysis (HP:0002105) | 2.67500965 |
| 44 | Cellulitis (HP:0100658) | 2.65177588 |
| 45 | Pulmonary infiltrates (HP:0002113) | 2.63972820 |
| 46 | Epistaxis (HP:0000421) | 2.62346300 |
| 47 | Viral hepatitis (HP:0006562) | 2.61822148 |
| 48 | Abnormality of T cell number (HP:0011839) | 2.57867124 |
| 49 | Arterial thrombosis (HP:0004420) | 2.56043133 |
| 50 | Abnormality of T cells (HP:0002843) | 2.51311305 |
| 51 | Urticaria (HP:0001025) | 2.51214812 |
| 52 | Leukocytosis (HP:0001974) | 2.44786439 |
| 53 | Hypochromic anemia (HP:0001931) | 2.44510646 |
| 54 | Granulocytopenia (HP:0001913) | 2.44190300 |
| 55 | Papilledema (HP:0001085) | 2.42609049 |
| 56 | Abnormality of the fingertips (HP:0001211) | 2.41797506 |
| 57 | Agammaglobulinemia (HP:0004432) | 2.32724396 |
| 58 | Increased IgM level (HP:0003496) | 2.31705451 |
| 59 | Joint hemorrhage (HP:0005261) | 2.29768143 |
| 60 | Slow saccadic eye movements (HP:0000514) | 2.25788003 |
| 61 | Anorexia (HP:0002039) | 2.24942528 |
| 62 | Amyloidosis (HP:0011034) | 2.23887516 |
| 63 | Abnormality of the endocardium (HP:0004306) | 2.20497788 |
| 64 | Abnormality of T cell physiology (HP:0011840) | 2.18670234 |
| 65 | Subacute progressive viral hepatitis (HP:0006572) | 2.18580572 |
| 66 | Peritonitis (HP:0002586) | 2.16503811 |
| 67 | Gangrene (HP:0100758) | 2.16320376 |
| 68 | Lymphopenia (HP:0001888) | 2.14424868 |
| 69 | Abnormality of the pleura (HP:0002103) | 2.11745776 |
| 70 | Joint swelling (HP:0001386) | 2.09797488 |
| 71 | Abnormality of the peritoneum (HP:0002585) | 2.07612569 |
| 72 | IgM deficiency (HP:0002850) | 2.05643532 |
| 73 | Sepsis (HP:0100806) | 1.99615951 |
| 74 | Papilloma (HP:0012740) | 1.96473461 |
| 75 | Verrucae (HP:0200043) | 1.96473461 |
| 76 | Acute hepatic failure (HP:0006554) | 1.93865362 |
| 77 | Hemorrhage of the eye (HP:0011885) | 1.93275434 |
| 78 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.92888405 |
| 79 | Glomerulopathy (HP:0100820) | 1.92323212 |
| 80 | Peripheral hypomyelination (HP:0007182) | 1.92222180 |
| 81 | Eosinophilia (HP:0001880) | 1.90860423 |
| 82 | Keratitis (HP:0000491) | 1.90192981 |
| 83 | Recurrent sinusitis (HP:0011108) | 1.89946547 |
| 84 | Osteomyelitis (HP:0002754) | 1.87748361 |
| 85 | Supernumerary ribs (HP:0005815) | 1.85335773 |
| 86 | Hypochromic microcytic anemia (HP:0004840) | 1.83930737 |
| 87 | Neuronal loss in central nervous system (HP:0002529) | 1.82451859 |
| 88 | Vertigo (HP:0002321) | 1.82425280 |
| 89 | Metaphyseal cupping (HP:0003021) | 1.82422361 |
| 90 | Difficulty running (HP:0009046) | 1.80091868 |
| 91 | Menorrhagia (HP:0000132) | 1.77886585 |
| 92 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.77537053 |
| 93 | Acne (HP:0001061) | 1.77412743 |
| 94 | Fatigue (HP:0012378) | 1.76568962 |
| 95 | Dislocated radial head (HP:0003083) | 1.76420313 |
| 96 | Thrombophlebitis (HP:0004418) | 1.76105798 |
| 97 | Basal cell carcinoma (HP:0002671) | 1.75356599 |
| 98 | Cheilitis (HP:0100825) | 1.75327285 |
| 99 | Abnormality of the radial head (HP:0003995) | 1.75236660 |
| 100 | Gastrointestinal stroma tumor (HP:0100723) | 1.74549345 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 3.71127114 |
| 2 | RIPK4 | 3.37004515 |
| 3 | PRPF4B | 3.12531274 |
| 4 | SIK2 | 2.99709486 |
| 5 | IRAK4 | 2.55351145 |
| 6 | TYK2 | 2.41983573 |
| 7 | BLK | 2.39344462 |
| 8 | MAP2K3 | 2.17308544 |
| 9 | FGFR4 | 2.13241319 |
| 10 | FES | 2.00100310 |
| 11 | SIK3 | 1.99451909 |
| 12 | TNK2 | 1.98087808 |
| 13 | CSK | 1.81387961 |
| 14 | GRK6 | 1.79465618 |
| 15 | TRIB3 | 1.74870233 |
| 16 | ZAP70 | 1.71728194 |
| 17 | TAOK3 | 1.62945255 |
| 18 | BTK | 1.61239153 |
| 19 | TXK | 1.61193279 |
| 20 | ERN1 | 1.58937034 |
| 21 | MARK2 | 1.57979126 |
| 22 | FGFR3 | 1.54904643 |
| 23 | IKBKE | 1.54701102 |
| 24 | MAP3K14 | 1.49362433 |
| 25 | EPHB1 | 1.46878884 |
| 26 | MAP3K13 | 1.46714993 |
| 27 | HCK | 1.44110722 |
| 28 | FGR | 1.43961238 |
| 29 | SYK | 1.39296071 |
| 30 | CDK12 | 1.39227325 |
| 31 | TAOK1 | 1.36468941 |
| 32 | KSR2 | 1.30606256 |
| 33 | ITK | 1.30193796 |
| 34 | JAK3 | 1.28002543 |
| 35 | PKN2 | 1.23749149 |
| 36 | MAP3K11 | 1.21007893 |
| 37 | JAK2 | 1.17151858 |
| 38 | TBK1 | 1.17150868 |
| 39 | JAK1 | 1.16200978 |
| 40 | SIK1 | 1.15905285 |
| 41 | MAP3K7 | 1.14871341 |
| 42 | DYRK1B | 1.06389400 |
| 43 | LCK | 1.05547803 |
| 44 | IRAK2 | 1.04576014 |
| 45 | ICK | 1.04143688 |
| 46 | CSF1R | 1.02562817 |
| 47 | MAP3K1 | 1.02454242 |
| 48 | MAP3K10 | 1.00737522 |
| 49 | LYN | 0.99313039 |
| 50 | RET | 0.99224323 |
| 51 | TYRO3 | 0.97232752 |
| 52 | MAPK12 | 0.96786968 |
| 53 | MARK3 | 0.91741128 |
| 54 | PDK1 | 0.91608419 |
| 55 | MAP2K4 | 0.91557681 |
| 56 | PASK | 0.86376351 |
| 57 | PRKD2 | 0.86009609 |
| 58 | MAP3K6 | 0.85295500 |
| 59 | CDC42BPA | 0.84625077 |
| 60 | CAMKK1 | 0.82312700 |
| 61 | IRAK1 | 0.81394674 |
| 62 | MAP3K3 | 0.79755176 |
| 63 | SGK3 | 0.77479340 |
| 64 | PTK6 | 0.77424381 |
| 65 | MAPK7 | 0.75800923 |
| 66 | SGK2 | 0.74307996 |
| 67 | IKBKB | 0.70630546 |
| 68 | PDPK1 | 0.69440754 |
| 69 | CAMK4 | 0.68879706 |
| 70 | YES1 | 0.65954629 |
| 71 | MATK | 0.65937202 |
| 72 | EPHA3 | 0.64278339 |
| 73 | MAP3K2 | 0.62299739 |
| 74 | BRD4 | 0.62104469 |
| 75 | CDK19 | 0.58587847 |
| 76 | FYN | 0.57804464 |
| 77 | SGK494 | 0.57563512 |
| 78 | SGK223 | 0.57563512 |
| 79 | HIPK2 | 0.56470606 |
| 80 | TEC | 0.56385548 |
| 81 | STK11 | 0.55254927 |
| 82 | NLK | 0.54313394 |
| 83 | FGFR2 | 0.53254581 |
| 84 | WNK1 | 0.48844895 |
| 85 | RPS6KC1 | 0.48185084 |
| 86 | RPS6KL1 | 0.48185084 |
| 87 | KIT | 0.48078692 |
| 88 | UHMK1 | 0.47927075 |
| 89 | KSR1 | 0.47797049 |
| 90 | NTRK2 | 0.46805474 |
| 91 | CHUK | 0.46461428 |
| 92 | MAPK11 | 0.45744221 |
| 93 | SMG1 | 0.43244969 |
| 94 | STK38 | 0.42232220 |
| 95 | RPS6KA6 | 0.41999562 |
| 96 | DYRK3 | 0.41188946 |
| 97 | PRKCQ | 0.40278586 |
| 98 | PRKCH | 0.40278032 |
| 99 | MAP3K5 | 0.40036188 |
| 100 | CDK4 | 0.39305446 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.68638130 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.44426251 |
| 3 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.39960731 |
| 4 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.16224595 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.15466417 |
| 6 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 2.04691617 |
| 7 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.01512969 |
| 8 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.99234476 |
| 9 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.98823616 |
| 10 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.95595450 |
| 11 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.84972305 |
| 12 | Other glycan degradation_Homo sapiens_hsa00511 | 1.76963609 |
| 13 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.76601472 |
| 14 | Tuberculosis_Homo sapiens_hsa05152 | 1.72084588 |
| 15 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.67539745 |
| 16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.59968429 |
| 17 | Measles_Homo sapiens_hsa05162 | 1.58545687 |
| 18 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.56193574 |
| 19 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.53189997 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.52338439 |
| 21 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.48980794 |
| 22 | Allograft rejection_Homo sapiens_hsa05330 | 1.39161501 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.34374129 |
| 24 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.34183804 |
| 25 | Influenza A_Homo sapiens_hsa05164 | 1.33907361 |
| 26 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.32874466 |
| 27 | Hepatitis B_Homo sapiens_hsa05161 | 1.31495409 |
| 28 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.31151853 |
| 29 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.29701698 |
| 30 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.28601262 |
| 31 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.27048799 |
| 32 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.22293757 |
| 33 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.19283593 |
| 34 | Endometrial cancer_Homo sapiens_hsa05213 | 1.18400916 |
| 35 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.18241388 |
| 36 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.17942383 |
| 37 | Legionellosis_Homo sapiens_hsa05134 | 1.15537058 |
| 38 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.14330249 |
| 39 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.13785752 |
| 40 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.13124789 |
| 41 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.11265379 |
| 42 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.09780462 |
| 43 | Malaria_Homo sapiens_hsa05144 | 1.05804672 |
| 44 | Hepatitis C_Homo sapiens_hsa05160 | 1.05364549 |
| 45 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.04415546 |
| 46 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.04391126 |
| 47 | Platelet activation_Homo sapiens_hsa04611 | 1.03166122 |
| 48 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.02173922 |
| 49 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.01808171 |
| 50 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.00668107 |
| 51 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.99857192 |
| 52 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.99792699 |
| 53 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.97622688 |
| 54 | Colorectal cancer_Homo sapiens_hsa05210 | 0.95933893 |
| 55 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.95755435 |
| 56 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.95376115 |
| 57 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.95137194 |
| 58 | Viral myocarditis_Homo sapiens_hsa05416 | 0.93838266 |
| 59 | Pertussis_Homo sapiens_hsa05133 | 0.93809431 |
| 60 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.91925230 |
| 61 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.90981263 |
| 62 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.86278024 |
| 63 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.86206719 |
| 64 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.84007101 |
| 65 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.80954685 |
| 66 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.79234193 |
| 67 | Insulin resistance_Homo sapiens_hsa04931 | 0.77889527 |
| 68 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.77251620 |
| 69 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.77177734 |
| 70 | Apoptosis_Homo sapiens_hsa04210 | 0.77046325 |
| 71 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.75354515 |
| 72 | Long-term potentiation_Homo sapiens_hsa04720 | 0.75139384 |
| 73 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.74795748 |
| 74 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.73833551 |
| 75 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.70658981 |
| 76 | Phagosome_Homo sapiens_hsa04145 | 0.70066372 |
| 77 | Endocytosis_Homo sapiens_hsa04144 | 0.68983519 |
| 78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.68230779 |
| 79 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.67897465 |
| 80 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.67742032 |
| 81 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.64481559 |
| 82 | Glioma_Homo sapiens_hsa05214 | 0.63755020 |
| 83 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.62160886 |
| 84 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.61640875 |
| 85 | Salmonella infection_Homo sapiens_hsa05132 | 0.60826408 |
| 86 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.60629164 |
| 87 | Shigellosis_Homo sapiens_hsa05131 | 0.60445461 |
| 88 | Prostate cancer_Homo sapiens_hsa05215 | 0.58182144 |
| 89 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.57518671 |
| 90 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.54722577 |
| 91 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.53473725 |
| 92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.53115541 |
| 93 | HTLV-I infection_Homo sapiens_hsa05166 | 0.52369705 |
| 94 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.50708862 |
| 95 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.49244317 |
| 96 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.47630112 |
| 97 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.47120882 |
| 98 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.45886679 |
| 99 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.45656096 |
| 100 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.41045758 |

