

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to peptidoglycan (GO:0032494) | 4.80291189 |
| 2 | negative regulation of interleukin-12 production (GO:0032695) | 4.72733826 |
| 3 | neutrophil activation involved in immune response (GO:0002283) | 4.05356876 |
| 4 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 4.01129391 |
| 5 | macrophage activation involved in immune response (GO:0002281) | 3.84723229 |
| 6 | immunoglobulin mediated immune response (GO:0016064) | 3.80551497 |
| 7 | NIK/NF-kappaB signaling (GO:0038061) | 3.67453214 |
| 8 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.66532295 |
| 9 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.59930372 |
| 10 | negative regulation of cell killing (GO:0031342) | 3.56714217 |
| 11 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.56714217 |
| 12 | T-helper 1 type immune response (GO:0042088) | 3.54258674 |
| 13 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.47403628 |
| 14 | positive regulation by symbiont of host defense response (GO:0052509) | 3.42556611 |
| 15 | modulation by symbiont of host defense response (GO:0052031) | 3.42556611 |
| 16 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.42556611 |
| 17 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.42556611 |
| 18 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.42556611 |
| 19 | modulation by symbiont of host immune response (GO:0052553) | 3.42556611 |
| 20 | myeloid dendritic cell differentiation (GO:0043011) | 3.39948088 |
| 21 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.38705395 |
| 22 | glycosphingolipid catabolic process (GO:0046479) | 3.38141911 |
| 23 | type I interferon signaling pathway (GO:0060337) | 3.31908147 |
| 24 | cellular response to type I interferon (GO:0071357) | 3.31908147 |
| 25 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 3.31843375 |
| 26 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.30109148 |
| 27 | response to type I interferon (GO:0034340) | 3.29016832 |
| 28 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.28442536 |
| 29 | positive regulation of antigen processing and presentation (GO:0002579) | 3.27896992 |
| 30 | regulation of mononuclear cell migration (GO:0071675) | 3.27384753 |
| 31 | regulation of chemokine biosynthetic process (GO:0045073) | 3.25340468 |
| 32 | regulation of cytokine secretion involved in immune response (GO:0002739) | 3.24648586 |
| 33 | regulation of podosome assembly (GO:0071801) | 3.19887633 |
| 34 | response to muramyl dipeptide (GO:0032495) | 3.17887573 |
| 35 | germinal center formation (GO:0002467) | 3.17809351 |
| 36 | regulation of antigen processing and presentation (GO:0002577) | 3.13228019 |
| 37 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 3.12463260 |
| 38 | myeloid dendritic cell activation (GO:0001773) | 3.11130351 |
| 39 | detection of other organism (GO:0098543) | 3.10843319 |
| 40 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.06675708 |
| 41 | granulocyte activation (GO:0036230) | 3.05540249 |
| 42 | response to protozoan (GO:0001562) | 3.03566020 |
| 43 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.03506574 |
| 44 | detection of molecule of bacterial origin (GO:0032490) | 3.02237402 |
| 45 | glycolipid catabolic process (GO:0019377) | 3.01950474 |
| 46 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.01499011 |
| 47 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.00082099 |
| 48 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.99335940 |
| 49 | regulation of vitamin metabolic process (GO:0030656) | 2.99189487 |
| 50 | detection of bacterium (GO:0016045) | 2.99135719 |
| 51 | oligosaccharide catabolic process (GO:0009313) | 2.97182529 |
| 52 | amino sugar catabolic process (GO:0046348) | 2.96660503 |
| 53 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.95710051 |
| 54 | regulation of mast cell degranulation (GO:0043304) | 2.93613327 |
| 55 | adhesion of symbiont to host cell (GO:0044650) | 2.91994262 |
| 56 | virion attachment to host cell (GO:0019062) | 2.91994262 |
| 57 | regulation of T cell tolerance induction (GO:0002664) | 2.91707869 |
| 58 | defense response to protozoan (GO:0042832) | 2.91017700 |
| 59 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.90447499 |
| 60 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.90368961 |
| 61 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.90099579 |
| 62 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.89657813 |
| 63 | detection of external biotic stimulus (GO:0098581) | 2.89580932 |
| 64 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.88624868 |
| 65 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.88250687 |
| 66 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.85132030 |
| 67 | myeloid cell activation involved in immune response (GO:0002275) | 2.83371997 |
| 68 | regulation of interferon-alpha production (GO:0032647) | 2.81052882 |
| 69 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.76847485 |
| 70 | positive regulation of heat generation (GO:0031652) | 2.76554615 |
| 71 | regulation of leukocyte degranulation (GO:0043300) | 2.71561354 |
| 72 | dendritic cell differentiation (GO:0097028) | 2.71403027 |
| 73 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 2.69160277 |
| 74 | adhesion of symbiont to host (GO:0044406) | 2.69075934 |
| 75 | macrophage activation (GO:0042116) | 2.66907681 |
| 76 | ceramide catabolic process (GO:0046514) | 2.66907393 |
| 77 | B cell mediated immunity (GO:0019724) | 2.66013566 |
| 78 | regulation of tolerance induction (GO:0002643) | 2.65297486 |
| 79 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.64581188 |
| 80 | cellular response to interferon-gamma (GO:0071346) | 2.63904804 |
| 81 | detection of biotic stimulus (GO:0009595) | 2.63581258 |
| 82 | monocyte chemotaxis (GO:0002548) | 2.63512531 |
| 83 | cellular response to lipopolysaccharide (GO:0071222) | 2.62999349 |
| 84 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.62982708 |
| 85 | neutrophil activation (GO:0042119) | 2.62466766 |
| 86 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 2.62426668 |
| 87 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.60784016 |
| 88 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.60432021 |
| 89 | regulation of type 2 immune response (GO:0002828) | 2.59849379 |
| 90 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.59822493 |
| 91 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.59373080 |
| 92 | regulation of interleukin-12 production (GO:0032655) | 2.59305261 |
| 93 | positive regulation of type 2 immune response (GO:0002830) | 2.57848069 |
| 94 | pinocytosis (GO:0006907) | 2.57542505 |
| 95 | leukocyte aggregation (GO:0070486) | 2.56673822 |
| 96 | mannose metabolic process (GO:0006013) | 2.56584777 |
| 97 | cellular response to molecule of bacterial origin (GO:0071219) | 2.55127132 |
| 98 | regulation of gamma-delta T cell activation (GO:0046643) | 2.53854448 |
| 99 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.52946664 |
| 100 | regulation of fever generation (GO:0031620) | 2.52267791 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.43959837 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.83937577 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.44325386 |
| 4 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 3.28377806 |
| 5 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.78220484 |
| 6 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.77274140 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.76319614 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.65390444 |
| 9 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.54375709 |
| 10 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.45829864 |
| 11 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.40374612 |
| 12 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.38747494 |
| 13 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.34609373 |
| 14 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.31419672 |
| 15 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.22167406 |
| 16 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.17171523 |
| 17 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.16623306 |
| 18 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.13136723 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.12727126 |
| 20 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.04360919 |
| 21 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.03905722 |
| 22 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.03700477 |
| 23 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.99679174 |
| 24 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.91809859 |
| 25 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.91660773 |
| 26 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.87333631 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.83494823 |
| 28 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.83184938 |
| 29 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.80452114 |
| 30 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.77618037 |
| 31 | SPI1_23127762_ChIP-Seq_K562_Human | 1.74997514 |
| 32 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.74797352 |
| 33 | MAF_26560356_Chip-Seq_TH1_Human | 1.69483955 |
| 34 | MYC_22102868_ChIP-Seq_BL_Human | 1.69367130 |
| 35 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.69352173 |
| 36 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.67152848 |
| 37 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.66344062 |
| 38 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.66189490 |
| 39 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.65264037 |
| 40 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.63486898 |
| 41 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.62195671 |
| 42 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53561600 |
| 43 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.51665925 |
| 44 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.46836788 |
| 45 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.44148093 |
| 46 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.43221436 |
| 47 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.42765601 |
| 48 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.42331604 |
| 49 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.42158596 |
| 50 | UTX_26944678_Chip-Seq_JUKART_Human | 1.40997998 |
| 51 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.39185666 |
| 52 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.37937673 |
| 53 | MAF_26560356_Chip-Seq_TH2_Human | 1.37769760 |
| 54 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.33142149 |
| 55 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.32502475 |
| 56 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.31144132 |
| 57 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.28274576 |
| 58 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.28163650 |
| 59 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.26658598 |
| 60 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.25427605 |
| 61 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.24134816 |
| 62 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22403470 |
| 63 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.21516031 |
| 64 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.21429458 |
| 65 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.19289521 |
| 66 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.19002739 |
| 67 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.18916763 |
| 68 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.15852930 |
| 69 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.15328477 |
| 70 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.14833335 |
| 71 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14055327 |
| 72 | KDM2B_26808549_Chip-Seq_K562_Human | 1.13593749 |
| 73 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.13162927 |
| 74 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.13076281 |
| 75 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.11898391 |
| 76 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11769626 |
| 77 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.11439546 |
| 78 | GATA1_19941826_ChIP-Seq_K562_Human | 1.11338505 |
| 79 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.09888596 |
| 80 | GATA1_22025678_ChIP-Seq_K562_Human | 1.09641852 |
| 81 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.09331955 |
| 82 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.09314987 |
| 83 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08565244 |
| 84 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.08205734 |
| 85 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.07874178 |
| 86 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.07776168 |
| 87 | MYB_26560356_Chip-Seq_TH2_Human | 1.06972060 |
| 88 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.06575500 |
| 89 | MYB_26560356_Chip-Seq_TH1_Human | 1.05519673 |
| 90 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.05366659 |
| 91 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.03823883 |
| 92 | * P68_20966046_ChIP-Seq_HELA_Human | 1.02262385 |
| 93 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.01685036 |
| 94 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.01489829 |
| 95 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.01374563 |
| 96 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.99740801 |
| 97 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.98905929 |
| 98 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.98281464 |
| 99 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.96257255 |
| 100 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.95323942 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 4.32328507 |
| 2 | MP0005058_abnormal_lysosome_morphology | 4.04286135 |
| 3 | MP0003436_decreased_susceptibility_to | 3.57008713 |
| 4 | MP0009840_abnormal_foam_cell | 3.16675670 |
| 5 | MP0003724_increased_susceptibility_to | 3.13456791 |
| 6 | MP0006082_CNS_inflammation | 3.11509638 |
| 7 | MP0002148_abnormal_hypersensitivity_rea | 2.91582684 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.81783776 |
| 9 | MP0009785_altered_susceptibility_to | 2.80472706 |
| 10 | MP0004510_myositis | 2.65920943 |
| 11 | MP0002419_abnormal_innate_immunity | 2.58710099 |
| 12 | MP0005000_abnormal_immune_tolerance | 2.47385333 |
| 13 | MP0001790_abnormal_immune_system | 2.42994633 |
| 14 | MP0005387_immune_system_phenotype | 2.42994633 |
| 15 | MP0003172_abnormal_lysosome_physiology | 2.42551903 |
| 16 | MP0005671_abnormal_response_to | 2.42499160 |
| 17 | MP0005025_abnormal_response_to | 2.39805249 |
| 18 | MP0003300_gastrointestinal_ulcer | 2.34099898 |
| 19 | MP0005451_abnormal_body_composition | 2.29988360 |
| 20 | MP0003191_abnormal_cellular_cholesterol | 2.20572098 |
| 21 | MP0002139_abnormal_hepatobiliary_system | 2.16284280 |
| 22 | MP0001533_abnormal_skeleton_physiology | 2.10739922 |
| 23 | MP0000685_abnormal_immune_system | 2.05845816 |
| 24 | MP0002452_abnormal_antigen_presenting | 2.04502696 |
| 25 | MP0000343_altered_response_to | 2.03229414 |
| 26 | MP0002723_abnormal_immune_serum | 2.01907637 |
| 27 | MP0001800_abnormal_humoral_immune | 2.00620391 |
| 28 | MP0003075_altered_response_to | 1.97564453 |
| 29 | MP0009764_decreased_sensitivity_to | 1.93652556 |
| 30 | MP0004947_skin_inflammation | 1.90249143 |
| 31 | MP0009278_abnormal_bone_marrow | 1.83866591 |
| 32 | MP0002420_abnormal_adaptive_immunity | 1.75785452 |
| 33 | MP0001819_abnormal_immune_cell | 1.75087140 |
| 34 | MP0002998_abnormal_bone_remodeling | 1.72842170 |
| 35 | MP0000604_amyloidosis | 1.72797081 |
| 36 | MP0001853_heart_inflammation | 1.64552656 |
| 37 | MP0010155_abnormal_intestine_physiology | 1.63438930 |
| 38 | MP0001845_abnormal_inflammatory_respons | 1.62158076 |
| 39 | MP0009333_abnormal_splenocyte_physiolog | 1.61047732 |
| 40 | MP0000858_altered_metastatic_potential | 1.58826488 |
| 41 | MP0002405_respiratory_system_inflammati | 1.57612790 |
| 42 | MP0003453_abnormal_keratinocyte_physiol | 1.57566022 |
| 43 | MP0005464_abnormal_platelet_physiology | 1.55378736 |
| 44 | MP0008469_abnormal_protein_level | 1.54432869 |
| 45 | MP0003806_abnormal_nucleotide_metabolis | 1.51311485 |
| 46 | MP0003705_abnormal_hypodermis_morpholog | 1.45316801 |
| 47 | MP0003448_altered_tumor_morphology | 1.45001375 |
| 48 | MP0008004_abnormal_stomach_pH | 1.40296665 |
| 49 | MP0005167_abnormal_blood-brain_barrier | 1.40047086 |
| 50 | MP0001545_abnormal_hematopoietic_system | 1.37864141 |
| 51 | MP0005397_hematopoietic_system_phenotyp | 1.37864141 |
| 52 | MP0008260_abnormal_autophagy | 1.31834846 |
| 53 | MP0005166_decreased_susceptibility_to | 1.31027260 |
| 54 | MP0003690_abnormal_glial_cell | 1.27499674 |
| 55 | MP0000716_abnormal_immune_system | 1.25125437 |
| 56 | MP0002254_reproductive_system_inflammat | 1.20694475 |
| 57 | MP0006054_spinal_hemorrhage | 1.13083745 |
| 58 | MP0005310_abnormal_salivary_gland | 1.10684752 |
| 59 | MP0002138_abnormal_hepatobiliary_system | 1.06886420 |
| 60 | MP0001542_abnormal_bone_strength | 1.05251509 |
| 61 | MP0002398_abnormal_bone_marrow | 1.05067494 |
| 62 | MP0003828_pulmonary_edema | 1.04786836 |
| 63 | MP0005390_skeleton_phenotype | 1.03979140 |
| 64 | MP0002332_abnormal_exercise_endurance | 1.03919558 |
| 65 | MP0005164_abnormal_response_to | 1.02962933 |
| 66 | MP0003279_aneurysm | 0.99443626 |
| 67 | MP0003091_abnormal_cell_migration | 0.99352338 |
| 68 | MP0003656_abnormal_erythrocyte_physiolo | 0.98655907 |
| 69 | MP0002933_joint_inflammation | 0.98416139 |
| 70 | MP0003763_abnormal_thymus_physiology | 0.97726252 |
| 71 | MP0005023_abnormal_wound_healing | 0.96929044 |
| 72 | MP0002429_abnormal_blood_cell | 0.96860721 |
| 73 | MP0003329_amyloid_beta_deposits | 0.93016481 |
| 74 | MP0000920_abnormal_myelination | 0.91789842 |
| 75 | MP0000249_abnormal_blood_vessel | 0.87495847 |
| 76 | MP0000689_abnormal_spleen_morphology | 0.87427558 |
| 77 | MP0004883_abnormal_blood_vessel | 0.86102664 |
| 78 | MP0009763_increased_sensitivity_to | 0.85105975 |
| 79 | MP0001663_abnormal_digestive_system | 0.84348417 |
| 80 | MP0003795_abnormal_bone_structure | 0.84044461 |
| 81 | MP0002277_abnormal_respiratory_mucosa | 0.82739697 |
| 82 | MP0002722_abnormal_immune_system | 0.81403514 |
| 83 | MP0005165_increased_susceptibility_to | 0.80848115 |
| 84 | MP0005365_abnormal_bile_salt | 0.77545425 |
| 85 | MP0008874_decreased_physiological_sensi | 0.76658763 |
| 86 | MP0001851_eye_inflammation | 0.75009737 |
| 87 | MP0001873_stomach_inflammation | 0.74038488 |
| 88 | MP0003879_abnormal_hair_cell | 0.73853840 |
| 89 | MP0005076_abnormal_cell_differentiation | 0.70215443 |
| 90 | MP0005319_abnormal_enzyme/_coenzyme | 0.69120589 |
| 91 | MP0002877_abnormal_melanocyte_morpholog | 0.68612997 |
| 92 | MP0005595_abnormal_vascular_smooth | 0.66191276 |
| 93 | MP0001849_ear_inflammation | 0.64133263 |
| 94 | MP0000465_gastrointestinal_hemorrhage | 0.64036009 |
| 95 | MP0003183_abnormal_peptide_metabolism | 0.63012888 |
| 96 | MP0000609_abnormal_liver_physiology | 0.61969845 |
| 97 | MP0009765_abnormal_xenobiotic_induced | 0.60737473 |
| 98 | MP0004808_abnormal_hematopoietic_stem | 0.59810749 |
| 99 | MP0003634_abnormal_glial_cell | 0.58510662 |
| 100 | MP0001958_emphysema | 0.57057163 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of liposaccharide metabolism (HP:0010968) | 6.25768672 |
| 2 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 6.25768672 |
| 3 | Abnormality of glycolipid metabolism (HP:0010969) | 6.25768672 |
| 4 | Increased cerebral lipofuscin (HP:0011813) | 4.81712360 |
| 5 | Vacuolated lymphocytes (HP:0001922) | 4.77215227 |
| 6 | Systemic lupus erythematosus (HP:0002725) | 4.67922590 |
| 7 | Abnormality of macrophages (HP:0004311) | 4.66925652 |
| 8 | Dysostosis multiplex (HP:0000943) | 4.47118647 |
| 9 | Eczematoid dermatitis (HP:0000976) | 4.21660745 |
| 10 | Loss of speech (HP:0002371) | 4.15513110 |
| 11 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 4.13755849 |
| 12 | Recurrent bacterial skin infections (HP:0005406) | 3.81803555 |
| 13 | Recurrent abscess formation (HP:0002722) | 3.81268784 |
| 14 | Orchitis (HP:0100796) | 3.68728562 |
| 15 | Myositis (HP:0100614) | 3.64772888 |
| 16 | Abnormality of polysaccharide metabolism (HP:0011012) | 3.42551541 |
| 17 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 3.42551541 |
| 18 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 3.42551541 |
| 19 | Optic neuritis (HP:0100653) | 3.39782263 |
| 20 | Retrobulbar optic neuritis (HP:0100654) | 3.39782263 |
| 21 | Disinhibition (HP:0000734) | 3.33011189 |
| 22 | Urinary glycosaminoglycan excretion (HP:0003541) | 3.24671342 |
| 23 | Mucopolysacchariduria (HP:0008155) | 3.24671342 |
| 24 | Axonal loss (HP:0003447) | 3.23613649 |
| 25 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.21958320 |
| 26 | Mediastinal lymphadenopathy (HP:0100721) | 3.18428816 |
| 27 | Stomatitis (HP:0010280) | 3.17399821 |
| 28 | Neurofibrillary tangles (HP:0002185) | 3.00665212 |
| 29 | Nuclear cataract (HP:0100018) | 2.99079457 |
| 30 | Glomerulonephritis (HP:0000099) | 2.98543639 |
| 31 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.94202431 |
| 32 | Increased serum ferritin (HP:0003281) | 2.87366884 |
| 33 | Amyloidosis (HP:0011034) | 2.85162199 |
| 34 | Autoimmune thrombocytopenia (HP:0001973) | 2.82719276 |
| 35 | Mutism (HP:0002300) | 2.81998063 |
| 36 | Obstructive lung disease (HP:0006536) | 2.72737441 |
| 37 | Chronic obstructive pulmonary disease (HP:0006510) | 2.72737441 |
| 38 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.66047472 |
| 39 | Purpura (HP:0000979) | 2.62376030 |
| 40 | Pulmonary infiltrates (HP:0002113) | 2.57794955 |
| 41 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.52440214 |
| 42 | Complement deficiency (HP:0004431) | 2.47354025 |
| 43 | Myocardial infarction (HP:0001658) | 2.39168838 |
| 44 | Vasculitis (HP:0002633) | 2.35663993 |
| 45 | Increased IgE level (HP:0003212) | 2.33977658 |
| 46 | Keratoconjunctivitis sicca (HP:0001097) | 2.33616413 |
| 47 | Recurrent skin infections (HP:0001581) | 2.33182122 |
| 48 | Abnormality of complement system (HP:0005339) | 2.31155362 |
| 49 | Neuronal loss in central nervous system (HP:0002529) | 2.31003079 |
| 50 | Hepatosplenomegaly (HP:0001433) | 2.30284919 |
| 51 | Asymmetric septal hypertrophy (HP:0001670) | 2.29108376 |
| 52 | Abnormality of iron homeostasis (HP:0011031) | 2.27063532 |
| 53 | Cellulitis (HP:0100658) | 2.26411337 |
| 54 | Gingivitis (HP:0000230) | 2.23994671 |
| 55 | Cerebral inclusion bodies (HP:0100314) | 2.23015867 |
| 56 | Diminished motivation (HP:0000745) | 2.21826517 |
| 57 | Petechiae (HP:0000967) | 2.21502090 |
| 58 | Meningitis (HP:0001287) | 2.21101982 |
| 59 | Upper motor neuron abnormality (HP:0002127) | 2.20795307 |
| 60 | Vertebral compression fractures (HP:0002953) | 2.18370289 |
| 61 | Apathy (HP:0000741) | 2.17805642 |
| 62 | Progressive neurologic deterioration (HP:0002344) | 2.17672627 |
| 63 | Malnutrition (HP:0004395) | 2.15782448 |
| 64 | Recurrent fungal infections (HP:0002841) | 2.15659059 |
| 65 | Spontaneous hematomas (HP:0007420) | 2.15194544 |
| 66 | Gangrene (HP:0100758) | 2.13725458 |
| 67 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.12696151 |
| 68 | Interstitial pulmonary disease (HP:0006530) | 2.11524879 |
| 69 | Hemoptysis (HP:0002105) | 2.11322767 |
| 70 | Gastrointestinal infarctions (HP:0005244) | 2.10398325 |
| 71 | Keratoconjunctivitis (HP:0001096) | 2.03818313 |
| 72 | Urticaria (HP:0001025) | 2.03722122 |
| 73 | J-shaped sella turcica (HP:0002680) | 1.99868435 |
| 74 | Pustule (HP:0200039) | 1.99411124 |
| 75 | Prolonged neonatal jaundice (HP:0006579) | 1.99030771 |
| 76 | Increased IgM level (HP:0003496) | 1.98173978 |
| 77 | Gastrointestinal stroma tumor (HP:0100723) | 1.97806101 |
| 78 | Recurrent viral infections (HP:0004429) | 1.96100887 |
| 79 | Hematochezia (HP:0002573) | 1.92411997 |
| 80 | Dementia (HP:0000726) | 1.92326691 |
| 81 | Polyneuropathy (HP:0001271) | 1.91123203 |
| 82 | Restrictive lung disease (HP:0002091) | 1.90928078 |
| 83 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.90018239 |
| 84 | Hypergammaglobulinemia (HP:0010702) | 1.85891580 |
| 85 | Personality changes (HP:0000751) | 1.85774881 |
| 86 | Colitis (HP:0002583) | 1.83683839 |
| 87 | Epistaxis (HP:0000421) | 1.81761640 |
| 88 | Bone pain (HP:0002653) | 1.81108112 |
| 89 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.80963691 |
| 90 | Encephalitis (HP:0002383) | 1.80640422 |
| 91 | Abnormality of the nasal mucosa (HP:0000433) | 1.80574587 |
| 92 | Spondylolisthesis (HP:0003302) | 1.79817927 |
| 93 | Pathologic fracture (HP:0002756) | 1.78058918 |
| 94 | Nephritis (HP:0000123) | 1.77541539 |
| 95 | Joint stiffness (HP:0001387) | 1.76505445 |
| 96 | Abnormality of the pleura (HP:0002103) | 1.76269258 |
| 97 | Emphysema (HP:0002097) | 1.74527524 |
| 98 | Arthralgia (HP:0002829) | 1.73894149 |
| 99 | Supranuclear gaze palsy (HP:0000605) | 1.73776024 |
| 100 | Thin bony cortex (HP:0002753) | 1.73497991 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRAK3 | 4.28377872 |
| 2 | TAOK2 | 3.20706989 |
| 3 | NME2 | 3.00102676 |
| 4 | RIPK4 | 2.79447238 |
| 5 | ERN1 | 2.70464227 |
| 6 | MAP4K1 | 2.60625614 |
| 7 | MAP3K14 | 2.56989731 |
| 8 | TBK1 | 2.51734692 |
| 9 | PRPF4B | 2.37522806 |
| 10 | TYK2 | 2.25853677 |
| 11 | MAP2K3 | 2.25461920 |
| 12 | MAP3K11 | 2.21295777 |
| 13 | BLK | 2.16065674 |
| 14 | RIPK1 | 2.11948266 |
| 15 | IRAK4 | 2.09812255 |
| 16 | MAP3K3 | 1.97846385 |
| 17 | GRK7 | 1.95955411 |
| 18 | DDR2 | 1.87509360 |
| 19 | TAOK1 | 1.86009009 |
| 20 | CSK | 1.81505786 |
| 21 | TRIB3 | 1.78375497 |
| 22 | IKBKB | 1.72055467 |
| 23 | TGFBR2 | 1.71833433 |
| 24 | IKBKE | 1.70779686 |
| 25 | MATK | 1.57934664 |
| 26 | ZAP70 | 1.56111226 |
| 27 | JAK3 | 1.55088375 |
| 28 | CDC42BPA | 1.52805487 |
| 29 | FGR | 1.52675574 |
| 30 | TXK | 1.41516744 |
| 31 | PIM2 | 1.35171754 |
| 32 | SIK1 | 1.32915335 |
| 33 | MAP3K13 | 1.29880139 |
| 34 | MOS | 1.27973273 |
| 35 | MAP3K1 | 1.23952527 |
| 36 | MAP2K6 | 1.12037580 |
| 37 | CSF1R | 1.09707607 |
| 38 | CHUK | 1.08932725 |
| 39 | ABL2 | 1.04811445 |
| 40 | BMPR2 | 0.99615832 |
| 41 | JAK1 | 0.99025970 |
| 42 | FES | 0.93078247 |
| 43 | TESK2 | 0.89174517 |
| 44 | IRAK1 | 0.88308953 |
| 45 | TNK2 | 0.87506212 |
| 46 | LYN | 0.87247736 |
| 47 | EPHB1 | 0.85732482 |
| 48 | SYK | 0.85568359 |
| 49 | KIT | 0.85381965 |
| 50 | IRAK2 | 0.84284733 |
| 51 | MAP3K5 | 0.81826699 |
| 52 | TAOK3 | 0.81182042 |
| 53 | TESK1 | 0.80455879 |
| 54 | SIK3 | 0.80127892 |
| 55 | TTN | 0.79519343 |
| 56 | TYRO3 | 0.74913696 |
| 57 | CAMKK2 | 0.74579689 |
| 58 | HCK | 0.74258655 |
| 59 | PRKD2 | 0.72828686 |
| 60 | BTK | 0.71774219 |
| 61 | JAK2 | 0.70294198 |
| 62 | MAPK7 | 0.70112237 |
| 63 | PDGFRA | 0.68497124 |
| 64 | LCK | 0.66258101 |
| 65 | MARK2 | 0.65789079 |
| 66 | PDPK1 | 0.64587495 |
| 67 | MARK3 | 0.63444917 |
| 68 | ARAF | 0.62723805 |
| 69 | MAPK11 | 0.61156103 |
| 70 | GRK6 | 0.60620759 |
| 71 | FGFR4 | 0.60232391 |
| 72 | SMG1 | 0.59847561 |
| 73 | RPS6KL1 | 0.56557286 |
| 74 | RPS6KC1 | 0.56557286 |
| 75 | HIPK2 | 0.55859156 |
| 76 | BMX | 0.54695050 |
| 77 | MAPK12 | 0.54627196 |
| 78 | PAK4 | 0.54366043 |
| 79 | MAPKAPK3 | 0.53965275 |
| 80 | PTK6 | 0.53695301 |
| 81 | STK10 | 0.53526281 |
| 82 | SIK2 | 0.53313434 |
| 83 | MAPK4 | 0.49742030 |
| 84 | ADRBK2 | 0.49258593 |
| 85 | DYRK1B | 0.46017689 |
| 86 | PDK1 | 0.45999072 |
| 87 | RPS6KA6 | 0.44746099 |
| 88 | ICK | 0.44082800 |
| 89 | NEK9 | 0.42699646 |
| 90 | RPS6KA2 | 0.41461031 |
| 91 | DAPK3 | 0.41316325 |
| 92 | CDK6 | 0.39688284 |
| 93 | MAPKAPK2 | 0.38807792 |
| 94 | PRKG2 | 0.38597718 |
| 95 | MAP3K8 | 0.37994829 |
| 96 | CAMKK1 | 0.36847277 |
| 97 | KSR2 | 0.35873954 |
| 98 | DAPK2 | 0.33756154 |
| 99 | PDGFRB | 0.33673671 |
| 100 | PIM1 | 0.32912045 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Other glycan degradation_Homo sapiens_hsa00511 | 3.47842175 |
| 2 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.82547790 |
| 3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.78564391 |
| 4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.65491590 |
| 5 | Lysosome_Homo sapiens_hsa04142 | 2.58165489 |
| 6 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.51745569 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.47845059 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.31611628 |
| 9 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.30836427 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.18688387 |
| 11 | Asthma_Homo sapiens_hsa05310 | 2.18103559 |
| 12 | Malaria_Homo sapiens_hsa05144 | 2.14100469 |
| 13 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.11735560 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.08723300 |
| 15 | Tuberculosis_Homo sapiens_hsa05152 | 2.00967291 |
| 16 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.98343054 |
| 17 | Pertussis_Homo sapiens_hsa05133 | 1.98005324 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.94447025 |
| 19 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.94446361 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.81849633 |
| 21 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.74698119 |
| 22 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.72136956 |
| 23 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.64998355 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.60666663 |
| 25 | Legionellosis_Homo sapiens_hsa05134 | 1.60123055 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.60062091 |
| 27 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.58044525 |
| 28 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.55080721 |
| 29 | Salmonella infection_Homo sapiens_hsa05132 | 1.54172358 |
| 30 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.53783043 |
| 31 | Influenza A_Homo sapiens_hsa05164 | 1.49726496 |
| 32 | Phagosome_Homo sapiens_hsa04145 | 1.45207424 |
| 33 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.36159798 |
| 34 | Viral myocarditis_Homo sapiens_hsa05416 | 1.34700238 |
| 35 | Prion diseases_Homo sapiens_hsa05020 | 1.31753637 |
| 36 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.31114669 |
| 37 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.29355553 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.28120778 |
| 39 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.20250415 |
| 40 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.20189675 |
| 41 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.14647973 |
| 42 | Hepatitis C_Homo sapiens_hsa05160 | 1.13462489 |
| 43 | Measles_Homo sapiens_hsa05162 | 1.12199256 |
| 44 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.10292122 |
| 45 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.05866409 |
| 46 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.05496523 |
| 47 | Bladder cancer_Homo sapiens_hsa05219 | 1.05123166 |
| 48 | Shigellosis_Homo sapiens_hsa05131 | 1.03089887 |
| 49 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.02204931 |
| 50 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.01129425 |
| 51 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.99480297 |
| 52 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.95790369 |
| 53 | Amoebiasis_Homo sapiens_hsa05146 | 0.94960511 |
| 54 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.94424000 |
| 55 | Apoptosis_Homo sapiens_hsa04210 | 0.93711965 |
| 56 | Hepatitis B_Homo sapiens_hsa05161 | 0.92653765 |
| 57 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.92429923 |
| 58 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.92059046 |
| 59 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.90073213 |
| 60 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.87875665 |
| 61 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.75492863 |
| 62 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.71889073 |
| 63 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.71818152 |
| 64 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.69648024 |
| 65 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.69498281 |
| 66 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.68057458 |
| 67 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.61127278 |
| 68 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.60822296 |
| 69 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.60057578 |
| 70 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.59564105 |
| 71 | Galactose metabolism_Homo sapiens_hsa00052 | 0.59366016 |
| 72 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.58122315 |
| 73 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.55754558 |
| 74 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52756384 |
| 75 | Endocytosis_Homo sapiens_hsa04144 | 0.49235023 |
| 76 | * SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46714821 |
| 77 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.46504503 |
| 78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.44797651 |
| 79 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.44356455 |
| 80 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.43756775 |
| 81 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.43474060 |
| 82 | Mineral absorption_Homo sapiens_hsa04978 | 0.42261052 |
| 83 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.41251840 |
| 84 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.40677170 |
| 85 | Insulin resistance_Homo sapiens_hsa04931 | 0.39364149 |
| 86 | Platelet activation_Homo sapiens_hsa04611 | 0.39181342 |
| 87 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.37785353 |
| 88 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.37513148 |
| 89 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.34453770 |
| 90 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.32416348 |
| 91 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.29255364 |
| 92 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.25584069 |
| 93 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.23794488 |
| 94 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.22951879 |
| 95 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.22043941 |
| 96 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.19000279 |
| 97 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.18208809 |
| 98 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.18154306 |
| 99 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.16063875 |
| 100 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.14585433 |

