Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.62176269 |
2 | * synaptic vesicle exocytosis (GO:0016079) | 4.20975120 |
3 | neuron cell-cell adhesion (GO:0007158) | 4.10514988 |
4 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.02422594 |
5 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.01023083 |
6 | detection of molecule of bacterial origin (GO:0032490) | 3.83138240 |
7 | microglial cell activation (GO:0001774) | 3.81432904 |
8 | synaptic vesicle maturation (GO:0016188) | 3.77435273 |
9 | interkinetic nuclear migration (GO:0022027) | 3.76982758 |
10 | B cell receptor signaling pathway (GO:0050853) | 3.68109801 |
11 | protein localization to synapse (GO:0035418) | 3.64798883 |
12 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.62078781 |
13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.58622522 |
14 | vocalization behavior (GO:0071625) | 3.54383773 |
15 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.43232310 |
16 | layer formation in cerebral cortex (GO:0021819) | 3.41045813 |
17 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.34594579 |
18 | positive regulation of mast cell activation (GO:0033005) | 3.34149913 |
19 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.34140645 |
20 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.32330711 |
21 | regulation of synaptic vesicle transport (GO:1902803) | 3.31724192 |
22 | negative regulation of cell killing (GO:0031342) | 3.31389005 |
23 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.31389005 |
24 | macrophage activation involved in immune response (GO:0002281) | 3.30483789 |
25 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.29712615 |
26 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.29712615 |
27 | modulation by symbiont of host immune response (GO:0052553) | 3.29712615 |
28 | positive regulation by symbiont of host defense response (GO:0052509) | 3.29712615 |
29 | modulation by symbiont of host defense response (GO:0052031) | 3.29712615 |
30 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.29712615 |
31 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.28825245 |
32 | neutrophil activation (GO:0042119) | 3.28221425 |
33 | regulation of pigment cell differentiation (GO:0050932) | 3.27315024 |
34 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.26900982 |
35 | glutamate secretion (GO:0014047) | 3.26834603 |
36 | tyrosine phosphorylation of STAT protein (GO:0007260) | 3.20756918 |
37 | locomotory exploration behavior (GO:0035641) | 3.18698831 |
38 | regulation of synapse structural plasticity (GO:0051823) | 3.14199087 |
39 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.12355778 |
40 | neural tube formation (GO:0001841) | 3.10614771 |
41 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.10392701 |
42 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.10392701 |
43 | phagosome maturation (GO:0090382) | 3.09013697 |
44 | neuron recognition (GO:0008038) | 3.07875386 |
45 | transferrin transport (GO:0033572) | 3.04096986 |
46 | cellular potassium ion homeostasis (GO:0030007) | 3.03867695 |
47 | detection of external biotic stimulus (GO:0098581) | 3.01019798 |
48 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.99633172 |
49 | detection of other organism (GO:0098543) | 2.99415803 |
50 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.97865023 |
51 | activated T cell proliferation (GO:0050798) | 2.97211456 |
52 | proline transport (GO:0015824) | 2.97172893 |
53 | postsynaptic membrane organization (GO:0001941) | 2.96744898 |
54 | regulation of mast cell activation (GO:0033003) | 2.93202480 |
55 | exploration behavior (GO:0035640) | 2.92874307 |
56 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.92658565 |
57 | positive regulation of mast cell degranulation (GO:0043306) | 2.92658565 |
58 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.88205459 |
59 | cellular extravasation (GO:0045123) | 2.84609143 |
60 | neutrophil mediated immunity (GO:0002446) | 2.84401820 |
61 | presynaptic membrane assembly (GO:0097105) | 2.84304588 |
62 | neurotransmitter secretion (GO:0007269) | 2.83763758 |
63 | trivalent inorganic cation transport (GO:0072512) | 2.82200777 |
64 | ferric iron transport (GO:0015682) | 2.82200777 |
65 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.81786921 |
66 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.81444199 |
67 | macrophage activation (GO:0042116) | 2.80534675 |
68 | granulocyte activation (GO:0036230) | 2.80347807 |
69 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 2.77210284 |
70 | vesicle transport along microtubule (GO:0047496) | 2.77105276 |
71 | dendrite morphogenesis (GO:0048813) | 2.76818355 |
72 | clathrin coat assembly (GO:0048268) | 2.75267463 |
73 | neuronal action potential propagation (GO:0019227) | 2.74004481 |
74 | myeloid leukocyte mediated immunity (GO:0002444) | 2.69310029 |
75 | presynaptic membrane organization (GO:0097090) | 2.69036862 |
76 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.68129987 |
77 | axonal fasciculation (GO:0007413) | 2.67969531 |
78 | negative regulation of microtubule polymerization (GO:0031115) | 2.67458148 |
79 | myeloid cell activation involved in immune response (GO:0002275) | 2.67386290 |
80 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.66887360 |
81 | negative regulation of B cell mediated immunity (GO:0002713) | 2.63618398 |
82 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.63618398 |
83 | regulation of amyloid precursor protein catabolic process (GO:1902991) | 2.62016327 |
84 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.61760590 |
85 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.61713773 |
86 | mating behavior (GO:0007617) | 2.59568095 |
87 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.59511421 |
88 | regulation of vesicle fusion (GO:0031338) | 2.59085077 |
89 | glutamate receptor signaling pathway (GO:0007215) | 2.58107066 |
90 | synaptic vesicle endocytosis (GO:0048488) | 2.56734179 |
91 | developmental pigmentation (GO:0048066) | 2.56543036 |
92 | sodium ion export (GO:0071436) | 2.55225539 |
93 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.54441716 |
94 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.53873262 |
95 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.53476463 |
96 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.51448641 |
97 | detection of bacterium (GO:0016045) | 2.51221552 |
98 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.50577315 |
99 | long-term synaptic potentiation (GO:0060291) | 2.50548608 |
100 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.50470704 |
101 | organelle transport along microtubule (GO:0072384) | 2.50352285 |
102 | nerve growth factor signaling pathway (GO:0038180) | 2.49474657 |
103 | synapse assembly (GO:0007416) | 2.44558273 |
104 | * synaptic vesicle transport (GO:0048489) | 2.43926226 |
105 | * establishment of synaptic vesicle localization (GO:0097480) | 2.43926226 |
106 | parental behavior (GO:0060746) | 2.43904481 |
107 | detection of biotic stimulus (GO:0009595) | 2.43868642 |
108 | * establishment of vesicle localization (GO:0051650) | 2.43407313 |
109 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 2.43297800 |
110 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 2.43297800 |
111 | neurotransmitter transport (GO:0006836) | 2.43132101 |
112 | regulation of beta-amyloid formation (GO:1902003) | 2.43085506 |
113 | protein targeting to lysosome (GO:0006622) | 2.43029736 |
114 | establishment of protein localization to vacuole (GO:0072666) | 2.43029736 |
115 | protein targeting to vacuole (GO:0006623) | 2.43029736 |
116 | sialylation (GO:0097503) | 2.42598829 |
117 | regulation of mast cell degranulation (GO:0043304) | 2.42541891 |
118 | positive regulation of macrophage cytokine production (GO:0060907) | 2.40464933 |
119 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.40301749 |
120 | maternal behavior (GO:0042711) | 2.40044562 |
121 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.38232859 |
122 | nucleobase catabolic process (GO:0046113) | 2.37907100 |
123 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 2.36918239 |
124 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.36302739 |
125 | nucleus localization (GO:0051647) | 2.35617287 |
126 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.35104396 |
127 | regulation of neurotransmitter secretion (GO:0046928) | 2.34914838 |
128 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 2.34817137 |
129 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.34191992 |
130 | neuron-neuron synaptic transmission (GO:0007270) | 2.33925210 |
131 | positive regulation of membrane potential (GO:0045838) | 2.33745684 |
132 | growth hormone receptor signaling pathway (GO:0060396) | 2.33608111 |
133 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.32881930 |
134 | negative regulation of neurotransmitter transport (GO:0051589) | 2.31997772 |
135 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.31362991 |
136 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.31260357 |
137 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.31226905 |
138 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.31084766 |
139 | positive regulation of synapse maturation (GO:0090129) | 2.30810120 |
140 | neutrophil activation involved in immune response (GO:0002283) | 2.30727165 |
141 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.30521718 |
142 | cellular response to ethanol (GO:0071361) | 2.30457510 |
143 | axon cargo transport (GO:0008088) | 2.29121330 |
144 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.28629269 |
145 | response to host immune response (GO:0052572) | 2.28597251 |
146 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.28597251 |
147 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.27941989 |
148 | negative regulation of exocytosis (GO:0045920) | 2.27760932 |
149 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.27368811 |
150 | response to auditory stimulus (GO:0010996) | 2.27127392 |
151 | positive regulation of granulocyte differentiation (GO:0030854) | 2.26729455 |
152 | innervation (GO:0060384) | 2.25736291 |
153 | synaptic transmission, glutamatergic (GO:0035249) | 2.25637790 |
154 | negative regulation of mast cell activation (GO:0033004) | 2.25126125 |
155 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.25031256 |
156 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.24939827 |
157 | positive regulation of interleukin-1 production (GO:0032732) | 2.24371670 |
158 | regulation of gamma-delta T cell activation (GO:0046643) | 2.24282255 |
159 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.24199465 |
160 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.23993267 |
161 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.22639512 |
162 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.22547291 |
163 | negative regulation of interleukin-17 production (GO:0032700) | 2.22306097 |
164 | regulation of neurotransmitter levels (GO:0001505) | 2.21953378 |
165 | regulation of postsynaptic membrane potential (GO:0060078) | 2.21571547 |
166 | regulation of mitochondrial depolarization (GO:0051900) | 2.21236604 |
167 | activation of protein kinase A activity (GO:0034199) | 2.20449529 |
168 | positive regulation of interleukin-1 beta production (GO:0032731) | 2.20079902 |
169 | T-helper 1 type immune response (GO:0042088) | 2.19877756 |
170 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.19716980 |
171 | melanin metabolic process (GO:0006582) | 2.19479116 |
172 | regulation of synaptic plasticity (GO:0048167) | 2.17667629 |
173 | dendrite development (GO:0016358) | 2.17583569 |
174 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 2.16875365 |
175 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 2.16875365 |
176 | peptide catabolic process (GO:0043171) | 2.16780782 |
177 | cellular response to nerve growth factor stimulus (GO:1990090) | 2.16364002 |
178 | response to nerve growth factor (GO:1990089) | 2.16364002 |
179 | regulation of exocytosis (GO:0017157) | 2.16236299 |
180 | cerebellar granule cell differentiation (GO:0021707) | 2.15609935 |
181 | regulation of antigen processing and presentation (GO:0002577) | 2.15485602 |
182 | positive regulation of synapse assembly (GO:0051965) | 2.15094624 |
183 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.14512839 |
184 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.13946642 |
185 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.13674750 |
186 | positive regulation of exocytosis (GO:0045921) | 2.13402214 |
187 | regulation of neurotransmitter transport (GO:0051588) | 2.11235588 |
188 | membrane assembly (GO:0071709) | 2.08373187 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.65407663 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.23359108 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.85089082 |
4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.66431579 |
5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.56524066 |
6 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.44186716 |
7 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.43406645 |
8 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.37400024 |
9 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.33551920 |
10 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.28761259 |
11 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.28524801 |
12 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.24080203 |
13 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.24080203 |
14 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.21518326 |
15 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.08923971 |
16 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.07825457 |
17 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.07746762 |
18 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.05799155 |
19 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.00406092 |
20 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.96772539 |
21 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.92973753 |
22 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.87512480 |
23 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.83799485 |
24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.79567754 |
25 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.78287964 |
26 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.77872792 |
27 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.77563870 |
28 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.75166270 |
29 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.75151045 |
30 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.74703048 |
31 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.72137351 |
32 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.67984135 |
33 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.66498286 |
34 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.65265626 |
35 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.65214036 |
36 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.64753337 |
37 | FUS_26573619_Chip-Seq_HEK293_Human | 1.63859752 |
38 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.61966182 |
39 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.61601486 |
40 | GATA1_22025678_ChIP-Seq_K562_Human | 1.59428086 |
41 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.58251009 |
42 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.56733416 |
43 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.56113371 |
44 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.55736296 |
45 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.53590476 |
46 | P300_19829295_ChIP-Seq_ESCs_Human | 1.52790874 |
47 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.51616614 |
48 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.51040931 |
49 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.51023605 |
50 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.47155946 |
51 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.44382231 |
52 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.44106114 |
53 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.43412162 |
54 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.40969602 |
55 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.40112934 |
56 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.36184245 |
57 | TP53_16413492_ChIP-PET_HCT116_Human | 1.34610464 |
58 | AR_25329375_ChIP-Seq_VCAP_Human | 1.33636634 |
59 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.33519631 |
60 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.33513248 |
61 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.33042328 |
62 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.33008988 |
63 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.32740590 |
64 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.32740590 |
65 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.32374670 |
66 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.30282694 |
67 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.29827726 |
68 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.28707660 |
69 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.28287340 |
70 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.28113141 |
71 | * CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.26864611 |
72 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.25776967 |
73 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.25136442 |
74 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.24563057 |
75 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.24540546 |
76 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.23765818 |
77 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.23056582 |
78 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.20470726 |
79 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.20276359 |
80 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.19951523 |
81 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.19581121 |
82 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.19350539 |
83 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.18039016 |
84 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.18039016 |
85 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.17970109 |
86 | KDM2B_26808549_Chip-Seq_REH_Human | 1.17835601 |
87 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.16865835 |
88 | VDR_22108803_ChIP-Seq_LS180_Human | 1.16431572 |
89 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.16216195 |
90 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.16216195 |
91 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.16096157 |
92 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.15563988 |
93 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.15120132 |
94 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.14844534 |
95 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.13488380 |
96 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.13353795 |
97 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.11443202 |
98 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.11319670 |
99 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.10968888 |
100 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.10700712 |
101 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.10512226 |
102 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.10450704 |
103 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.10199954 |
104 | * OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.10048793 |
105 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.09902447 |
106 | EWS_26573619_Chip-Seq_HEK293_Human | 1.09418423 |
107 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.08243945 |
108 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.08085873 |
109 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.07873166 |
110 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.07853310 |
111 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06953445 |
112 | * LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06843929 |
113 | STAT3_23295773_ChIP-Seq_U87_Human | 1.06036884 |
114 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.04685487 |
115 | * SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.04055513 |
116 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.03567397 |
117 | JUN_21703547_ChIP-Seq_K562_Human | 1.03533066 |
118 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.02989600 |
119 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.02297120 |
120 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.01817128 |
121 | * TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.01451189 |
122 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.00870114 |
123 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.00326556 |
124 | * CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.00190454 |
125 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99698738 |
126 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.99599849 |
127 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.98804547 |
128 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.98019152 |
129 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.96971441 |
130 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95747976 |
131 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.94881632 |
132 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.94562661 |
133 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.94480387 |
134 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.94290953 |
135 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.94042720 |
136 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.92467426 |
137 | RXR_22108803_ChIP-Seq_LS180_Human | 0.92388831 |
138 | * TCF4_23295773_ChIP-Seq_U87_Human | 0.90804210 |
139 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.90667965 |
140 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.89435472 |
141 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.88449992 |
142 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.88323730 |
143 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.88285295 |
144 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.88023827 |
145 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.86775232 |
146 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.86575073 |
147 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.85959869 |
148 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.85793188 |
149 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.85526353 |
150 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.85060239 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 4.00612472 |
2 | MP0003724_increased_susceptibility_to | 3.65660277 |
3 | MP0003880_abnormal_central_pattern | 3.65371992 |
4 | MP0004270_analgesia | 3.57040930 |
5 | MP0005174_abnormal_tail_pigmentation | 3.09861629 |
6 | MP0003635_abnormal_synaptic_transmissio | 2.96300176 |
7 | MP0002734_abnormal_mechanical_nocicepti | 2.74932712 |
8 | MP0002735_abnormal_chemical_nociception | 2.72462860 |
9 | MP0001968_abnormal_touch/_nociception | 2.67719034 |
10 | MP0002064_seizures | 2.54046502 |
11 | MP0002063_abnormal_learning/memory/cond | 2.47496907 |
12 | MP0003183_abnormal_peptide_metabolism | 2.47175085 |
13 | MP0003787_abnormal_imprinting | 2.39070929 |
14 | MP0009745_abnormal_behavioral_response | 2.36159282 |
15 | MP0002736_abnormal_nociception_after | 2.35555681 |
16 | MP0005075_abnormal_melanosome_morpholog | 2.32408959 |
17 | MP0009046_muscle_twitch | 2.29670321 |
18 | MP0002733_abnormal_thermal_nociception | 2.22253166 |
19 | MP0004858_abnormal_nervous_system | 2.20694248 |
20 | MP0009780_abnormal_chondrocyte_physiolo | 2.20522412 |
21 | MP0003329_amyloid_beta_deposits | 2.17768433 |
22 | MP0001970_abnormal_pain_threshold | 2.07832145 |
23 | MP0002572_abnormal_emotion/affect_behav | 2.06749917 |
24 | MP0002095_abnormal_skin_pigmentation | 2.00127932 |
25 | MP0005058_abnormal_lysosome_morphology | 1.96681134 |
26 | MP0005423_abnormal_somatic_nervous | 1.96381857 |
27 | MP0010386_abnormal_urinary_bladder | 1.95375611 |
28 | MP0005464_abnormal_platelet_physiology | 1.92280568 |
29 | MP0002272_abnormal_nervous_system | 1.91886549 |
30 | MP0006276_abnormal_autonomic_nervous | 1.89744642 |
31 | MP0001188_hyperpigmentation | 1.88681086 |
32 | MP0002909_abnormal_adrenal_gland | 1.84761987 |
33 | MP0003172_abnormal_lysosome_physiology | 1.83833652 |
34 | MP0001440_abnormal_grooming_behavior | 1.80462702 |
35 | MP0000465_gastrointestinal_hemorrhage | 1.77750044 |
36 | MP0005645_abnormal_hypothalamus_physiol | 1.77381682 |
37 | MP0002067_abnormal_sensory_capabilities | 1.76996118 |
38 | MP0001486_abnormal_startle_reflex | 1.76927725 |
39 | MP0001800_abnormal_humoral_immune | 1.76847882 |
40 | MP0004883_abnormal_blood_vessel | 1.76273873 |
41 | MP0001501_abnormal_sleep_pattern | 1.74398946 |
42 | MP0000604_amyloidosis | 1.70465372 |
43 | MP0003879_abnormal_hair_cell | 1.69756395 |
44 | MP0000920_abnormal_myelination | 1.67418914 |
45 | MP0000778_abnormal_nervous_system | 1.65474387 |
46 | MP0002184_abnormal_innervation | 1.62025603 |
47 | MP0002009_preneoplasia | 1.61812464 |
48 | MP0003122_maternal_imprinting | 1.61556561 |
49 | MP0005409_darkened_coat_color | 1.59049358 |
50 | MP0003690_abnormal_glial_cell | 1.56275496 |
51 | MP0002090_abnormal_vision | 1.55988450 |
52 | MP0002876_abnormal_thyroid_physiology | 1.55541073 |
53 | MP0005171_absent_coat_pigmentation | 1.55119344 |
54 | MP0003634_abnormal_glial_cell | 1.54798621 |
55 | MP0000371_diluted_coat_color | 1.51729048 |
56 | MP0003303_peritoneal_inflammation | 1.48257037 |
57 | MP0004381_abnormal_hair_follicle | 1.46157624 |
58 | MP0003828_pulmonary_edema | 1.45299838 |
59 | MP0004811_abnormal_neuron_physiology | 1.43408104 |
60 | MP0005408_hypopigmentation | 1.42798475 |
61 | MP0000372_irregular_coat_pigmentation | 1.42328579 |
62 | MP0002557_abnormal_social/conspecific_i | 1.38783518 |
63 | MP0002452_abnormal_antigen_presenting | 1.38484299 |
64 | MP0001790_abnormal_immune_system | 1.36806136 |
65 | MP0005387_immune_system_phenotype | 1.36806136 |
66 | MP0005167_abnormal_blood-brain_barrier | 1.35826920 |
67 | MP0004510_myositis | 1.33330068 |
68 | MP0004742_abnormal_vestibular_system | 1.33237090 |
69 | MP0009764_decreased_sensitivity_to | 1.32874781 |
70 | MP0005671_abnormal_response_to | 1.31537516 |
71 | MP0000013_abnormal_adipose_tissue | 1.29221810 |
72 | MP0004885_abnormal_endolymph | 1.28739059 |
73 | MP0004043_abnormal_pH_regulation | 1.28210094 |
74 | MP0002723_abnormal_immune_serum | 1.27823134 |
75 | MP0008569_lethality_at_weaning | 1.26809957 |
76 | MP0006054_spinal_hemorrhage | 1.25730810 |
77 | MP0002928_abnormal_bile_duct | 1.24980639 |
78 | MP0005386_behavior/neurological_phenoty | 1.24270840 |
79 | MP0004924_abnormal_behavior | 1.24270840 |
80 | MP0000955_abnormal_spinal_cord | 1.23674459 |
81 | MP0005310_abnormal_salivary_gland | 1.23334406 |
82 | MP0002882_abnormal_neuron_morphology | 1.21493610 |
83 | MP0001851_eye_inflammation | 1.19307018 |
84 | MP0003633_abnormal_nervous_system | 1.17932538 |
85 | MP0002420_abnormal_adaptive_immunity | 1.17717676 |
86 | MP0002066_abnormal_motor_capabilities/c | 1.16642496 |
87 | MP0003075_altered_response_to | 1.15964254 |
88 | MP0001348_abnormal_lacrimal_gland | 1.15379359 |
89 | MP0001819_abnormal_immune_cell | 1.15239936 |
90 | MP0001905_abnormal_dopamine_level | 1.14977258 |
91 | MP0003656_abnormal_erythrocyte_physiolo | 1.14933716 |
92 | MP0002229_neurodegeneration | 1.14523854 |
93 | MP0009785_altered_susceptibility_to | 1.09190254 |
94 | MP0001984_abnormal_olfaction | 1.08408540 |
95 | MP0003121_genomic_imprinting | 1.07821779 |
96 | MP0001879_abnormal_lymphatic_vessel | 1.06982816 |
97 | MP0001502_abnormal_circadian_rhythm | 1.06498404 |
98 | MP0005025_abnormal_response_to | 1.05644446 |
99 | MP0001529_abnormal_vocalization | 1.05606223 |
100 | MP0003221_abnormal_cardiomyocyte_apopto | 1.05370790 |
101 | MP0005646_abnormal_pituitary_gland | 1.03422898 |
102 | MP0008260_abnormal_autophagy | 1.01879654 |
103 | MP0000569_abnormal_digit_pigmentation | 1.00521634 |
104 | MP0001324_abnormal_eye_pigmentation | 0.99314679 |
105 | MP0002163_abnormal_gland_morphology | 0.97615016 |
106 | MP0003631_nervous_system_phenotype | 0.95359808 |
107 | MP0002075_abnormal_coat/hair_pigmentati | 0.95025239 |
108 | MP0001545_abnormal_hematopoietic_system | 0.94713014 |
109 | MP0005397_hematopoietic_system_phenotyp | 0.94713014 |
110 | MP0005535_abnormal_body_temperature | 0.93997739 |
111 | MP0003436_decreased_susceptibility_to | 0.92476364 |
112 | MP0005248_abnormal_Harderian_gland | 0.91888875 |
113 | MP0001986_abnormal_taste_sensitivity | 0.89345335 |
114 | MP0001963_abnormal_hearing_physiology | 0.88991166 |
115 | MP0004142_abnormal_muscle_tone | 0.87591225 |
116 | MP0002837_dystrophic_cardiac_calcinosis | 0.87532160 |
117 | MP0000685_abnormal_immune_system | 0.85897376 |
118 | MP0005164_abnormal_response_to | 0.85295165 |
119 | MP0000681_abnormal_thyroid_gland | 0.84478598 |
120 | MP0005379_endocrine/exocrine_gland_phen | 0.83924495 |
121 | MP0001186_pigmentation_phenotype | 0.83878110 |
122 | MP0002405_respiratory_system_inflammati | 0.83741808 |
123 | MP0005084_abnormal_gallbladder_morpholo | 0.83256963 |
124 | MP0000716_abnormal_immune_system | 0.82703132 |
125 | MP0001664_abnormal_digestion | 0.82462410 |
126 | MP0000343_altered_response_to | 0.80763618 |
127 | MP0002069_abnormal_eating/drinking_beha | 0.80236306 |
128 | MP0002148_abnormal_hypersensitivity_rea | 0.80123855 |
129 | MP0001835_abnormal_antigen_presentation | 0.79881137 |
130 | MP0005253_abnormal_eye_physiology | 0.79057072 |
131 | MP0006082_CNS_inflammation | 0.78903791 |
132 | MP0000689_abnormal_spleen_morphology | 0.78817889 |
133 | MP0002998_abnormal_bone_remodeling | 0.78563424 |
134 | MP0004130_abnormal_muscle_cell | 0.78025058 |
135 | MP0000538_abnormal_urinary_bladder | 0.74744347 |
136 | MP0002638_abnormal_pupillary_reflex | 0.73991858 |
137 | MP0010234_abnormal_vibrissa_follicle | 0.73813740 |
138 | MP0001765_abnormal_ion_homeostasis | 0.72653747 |
139 | MP0005551_abnormal_eye_electrophysiolog | 0.72072836 |
140 | MP0003632_abnormal_nervous_system | 0.71867084 |
141 | MP0002152_abnormal_brain_morphology | 0.69389278 |
142 | MP0002419_abnormal_innate_immunity | 0.63547268 |
143 | MP0001756_abnormal_urination | 0.63196609 |
144 | MP0005000_abnormal_immune_tolerance | 0.62988499 |
145 | MP0008004_abnormal_stomach_pH | 0.61736928 |
146 | MP0000751_myopathy | 0.61585549 |
147 | MP0002752_abnormal_somatic_nervous | 0.61433498 |
148 | MP0005166_decreased_susceptibility_to | 0.61234942 |
149 | MP0000015_abnormal_ear_pigmentation | 0.60636169 |
150 | MP0008874_decreased_physiological_sensi | 0.59645785 |
151 | MP0004484_altered_response_of | 0.59446200 |
152 | MP0002822_catalepsy | 0.59375771 |
153 | MP0001958_emphysema | 0.58787449 |
154 | MP0001485_abnormal_pinna_reflex | 0.58121165 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Supranuclear gaze palsy (HP:0000605) | 4.48599663 |
2 | Mutism (HP:0002300) | 4.26926273 |
3 | Focal motor seizures (HP:0011153) | 4.23894146 |
4 | Neurofibrillary tangles (HP:0002185) | 4.22767709 |
5 | Myokymia (HP:0002411) | 4.15405933 |
6 | Visual hallucinations (HP:0002367) | 3.94388028 |
7 | Increased cerebral lipofuscin (HP:0011813) | 3.91701875 |
8 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.62750099 |
9 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.54190961 |
10 | Atonic seizures (HP:0010819) | 3.52315946 |
11 | Pheochromocytoma (HP:0002666) | 3.50960125 |
12 | Cerebral inclusion bodies (HP:0100314) | 3.48214125 |
13 | Focal seizures (HP:0007359) | 3.41532418 |
14 | Dysostosis multiplex (HP:0000943) | 3.37454298 |
15 | Neuroendocrine neoplasm (HP:0100634) | 3.24819407 |
16 | Spontaneous hematomas (HP:0007420) | 3.22774217 |
17 | Papilledema (HP:0001085) | 3.18139163 |
18 | Epileptic encephalopathy (HP:0200134) | 3.17968543 |
19 | Gingival bleeding (HP:0000225) | 3.16949376 |
20 | Gastrointestinal infarctions (HP:0005244) | 3.07013872 |
21 | Akinesia (HP:0002304) | 3.04166751 |
22 | Papillary thyroid carcinoma (HP:0002895) | 3.02623034 |
23 | Peritonitis (HP:0002586) | 2.97463185 |
24 | Polyphagia (HP:0002591) | 2.95413913 |
25 | Ankle clonus (HP:0011448) | 2.95234500 |
26 | Conjunctival telangiectasia (HP:0000524) | 2.92500596 |
27 | Prolonged bleeding time (HP:0003010) | 2.89087059 |
28 | Abnormality of glycolipid metabolism (HP:0010969) | 2.88975946 |
29 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.88975946 |
30 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.88975946 |
31 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.88602759 |
32 | Progressive inability to walk (HP:0002505) | 2.88439106 |
33 | Absence seizures (HP:0002121) | 2.88292234 |
34 | Generalized tonic-clonic seizures (HP:0002069) | 2.81959183 |
35 | Dialeptic seizures (HP:0011146) | 2.77700968 |
36 | Abnormality of binocular vision (HP:0011514) | 2.74757764 |
37 | Diplopia (HP:0000651) | 2.74757764 |
38 | Mucopolysacchariduria (HP:0008155) | 2.70531472 |
39 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.70531472 |
40 | Abnormal eating behavior (HP:0100738) | 2.70094566 |
41 | Amyotrophic lateral sclerosis (HP:0007354) | 2.69470536 |
42 | Apathy (HP:0000741) | 2.65941000 |
43 | Action tremor (HP:0002345) | 2.63963492 |
44 | Heterochromia iridis (HP:0001100) | 2.63906836 |
45 | Limb dystonia (HP:0002451) | 2.61429719 |
46 | Choroideremia (HP:0001139) | 2.60596569 |
47 | Diminished motivation (HP:0000745) | 2.57224362 |
48 | Ocular albinism (HP:0001107) | 2.55280422 |
49 | Neuronal loss in central nervous system (HP:0002529) | 2.54369744 |
50 | Generalized hypopigmentation (HP:0007513) | 2.51995050 |
51 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.49306565 |
52 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.49306565 |
53 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.49306565 |
54 | Increased circulating renin level (HP:0000848) | 2.49199867 |
55 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.47850079 |
56 | Recurrent cutaneous fungal infections (HP:0011370) | 2.47850079 |
57 | Mediastinal lymphadenopathy (HP:0100721) | 2.46722225 |
58 | Optic neuritis (HP:0100653) | 2.46487477 |
59 | Retrobulbar optic neuritis (HP:0100654) | 2.46487477 |
60 | Progressive cerebellar ataxia (HP:0002073) | 2.45609934 |
61 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.44922884 |
62 | Chest pain (HP:0100749) | 2.44495945 |
63 | Hematochezia (HP:0002573) | 2.43821505 |
64 | Vacuolated lymphocytes (HP:0001922) | 2.43433669 |
65 | Disinhibition (HP:0000734) | 2.42662344 |
66 | Iris hypopigmentation (HP:0007730) | 2.42507960 |
67 | Febrile seizures (HP:0002373) | 2.41201112 |
68 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.39192754 |
69 | Recurrent skin infections (HP:0001581) | 2.36457919 |
70 | Epistaxis (HP:0000421) | 2.36082528 |
71 | Agammaglobulinemia (HP:0004432) | 2.31846016 |
72 | Inappropriate behavior (HP:0000719) | 2.31336345 |
73 | Insidious onset (HP:0003587) | 2.30721692 |
74 | Termporal pattern (HP:0011008) | 2.30721692 |
75 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.30087721 |
76 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.29372534 |
77 | Recurrent fungal infections (HP:0002841) | 2.28976365 |
78 | Genetic anticipation (HP:0003743) | 2.28159053 |
79 | Vasculitis (HP:0002633) | 2.27091254 |
80 | Metabolic alkalosis (HP:0200114) | 2.26041023 |
81 | Abnormal platelet volume (HP:0011876) | 2.23310327 |
82 | Acute hepatic failure (HP:0006554) | 2.23191585 |
83 | Hyperventilation (HP:0002883) | 2.22879806 |
84 | Hypochromic microcytic anemia (HP:0004840) | 2.22170000 |
85 | Agitation (HP:0000713) | 2.21173006 |
86 | Encephalitis (HP:0002383) | 2.20366904 |
87 | Orchitis (HP:0100796) | 2.20078109 |
88 | Absent speech (HP:0001344) | 2.19061356 |
89 | Anxiety (HP:0000739) | 2.18894760 |
90 | Recurrent bronchitis (HP:0002837) | 2.18523891 |
91 | Blue irides (HP:0000635) | 2.18328927 |
92 | Hypomagnesemia (HP:0002917) | 2.16116222 |
93 | Postural instability (HP:0002172) | 2.16059878 |
94 | Abnormality of the corticospinal tract (HP:0002492) | 2.15270681 |
95 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.14491584 |
96 | Meningitis (HP:0001287) | 2.14483914 |
97 | Albinism (HP:0001022) | 2.13495395 |
98 | Megalencephaly (HP:0001355) | 2.13340690 |
99 | Depression (HP:0000716) | 2.12984293 |
100 | T lymphocytopenia (HP:0005403) | 2.12481206 |
101 | Abnormality of T cell number (HP:0011839) | 2.12071114 |
102 | Pulmonary embolism (HP:0002204) | 2.11884438 |
103 | Increased mean platelet volume (HP:0011877) | 2.11741671 |
104 | Abnormality of macrophages (HP:0004311) | 2.10870115 |
105 | Drooling (HP:0002307) | 2.10570582 |
106 | Excessive salivation (HP:0003781) | 2.10570582 |
107 | Myositis (HP:0100614) | 2.10426382 |
108 | Hypokalemic alkalosis (HP:0001949) | 2.10074465 |
109 | Gait imbalance (HP:0002141) | 2.07197847 |
110 | Dementia (HP:0000726) | 2.07192771 |
111 | Truncal ataxia (HP:0002078) | 2.06673084 |
112 | Generalized hypopigmentation of hair (HP:0011358) | 2.06365651 |
113 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.06080625 |
114 | Recurrent sinusitis (HP:0011108) | 2.04706999 |
115 | Failure to thrive in infancy (HP:0001531) | 2.04464725 |
116 | Cerebral hemorrhage (HP:0001342) | 2.04072414 |
117 | Recurrent abscess formation (HP:0002722) | 2.03176038 |
118 | Axonal loss (HP:0003447) | 2.00606827 |
119 | Rapidly progressive (HP:0003678) | 1.98599558 |
120 | Acanthocytosis (HP:0001927) | 1.97976975 |
121 | Hemoptysis (HP:0002105) | 1.95725064 |
122 | Clumsiness (HP:0002312) | 1.93715507 |
123 | Gingivitis (HP:0000230) | 1.93157476 |
124 | Psychosis (HP:0000709) | 1.92902654 |
125 | Spastic gait (HP:0002064) | 1.92281183 |
126 | Abnormality of magnesium homeostasis (HP:0004921) | 1.91104713 |
127 | Stomatitis (HP:0010280) | 1.90204277 |
128 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.89808686 |
129 | Hyperactive renin-angiotensin system (HP:0000841) | 1.89739248 |
130 | Hemiparesis (HP:0001269) | 1.89645572 |
131 | Hemiplegia (HP:0002301) | 1.89046376 |
132 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.88398157 |
133 | Amblyopia (HP:0000646) | 1.87887196 |
134 | Keratoconjunctivitis sicca (HP:0001097) | 1.87807475 |
135 | Retinal dysplasia (HP:0007973) | 1.87708404 |
136 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.87456004 |
137 | Progressive neurologic deterioration (HP:0002344) | 1.86984513 |
138 | Arterial thrombosis (HP:0004420) | 1.86799378 |
139 | Viral hepatitis (HP:0006562) | 1.86636733 |
140 | Abnormality of the peritoneum (HP:0002585) | 1.86383624 |
141 | Dysmetria (HP:0001310) | 1.85852128 |
142 | Hip dysplasia (HP:0001385) | 1.85357574 |
143 | Abnormality of renin-angiotensin system (HP:0000847) | 1.84904508 |
144 | Absent/shortened dynein arms (HP:0200106) | 1.83943677 |
145 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.83943677 |
146 | Lower limb muscle weakness (HP:0007340) | 1.82797656 |
147 | Hypothermia (HP:0002045) | 1.82779614 |
148 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.82497820 |
149 | Recurrent bacterial skin infections (HP:0005406) | 1.81490949 |
150 | Recurrent pneumonia (HP:0006532) | 1.80528344 |
151 | Leukocytosis (HP:0001974) | 1.80385165 |
152 | Loss of speech (HP:0002371) | 1.80223215 |
153 | Hypercortisolism (HP:0001578) | 1.80164436 |
154 | Stomach cancer (HP:0012126) | 1.79874551 |
155 | Dyskinesia (HP:0100660) | 1.79063035 |
156 | Abnormality of salivation (HP:0100755) | 1.77798537 |
157 | Scanning speech (HP:0002168) | 1.76712581 |
158 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.76048138 |
159 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.76048138 |
160 | Generalized myoclonic seizures (HP:0002123) | 1.75858382 |
161 | Broad-based gait (HP:0002136) | 1.75841664 |
162 | Diminished movement (HP:0002374) | 1.75755568 |
163 | Keratoconjunctivitis (HP:0001096) | 1.75500237 |
164 | Thyroid carcinoma (HP:0002890) | 1.75462382 |
165 | Epileptiform EEG discharges (HP:0011182) | 1.75449276 |
166 | Inability to walk (HP:0002540) | 1.72449134 |
167 | Eczematoid dermatitis (HP:0000976) | 1.72398254 |
168 | EEG with generalized epileptiform discharges (HP:0011198) | 1.70937781 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MARK1 | 4.12738002 |
2 | MAP3K9 | 3.18216237 |
3 | TIE1 | 3.04206513 |
4 | CASK | 2.80448774 |
5 | NTRK3 | 2.63886333 |
6 | RIPK4 | 2.57929574 |
7 | MINK1 | 2.38358720 |
8 | MAP3K12 | 2.31074369 |
9 | MAP3K4 | 2.25821268 |
10 | TEC | 2.09542426 |
11 | MAP2K7 | 2.08687083 |
12 | KSR2 | 2.08581714 |
13 | NTRK1 | 1.98196893 |
14 | ACVR1B | 1.89959938 |
15 | ARAF | 1.88062139 |
16 | MAP3K2 | 1.83928198 |
17 | OXSR1 | 1.83799527 |
18 | LIMK1 | 1.74340162 |
19 | STK38L | 1.73511756 |
20 | STK24 | 1.70077995 |
21 | MAP3K6 | 1.67277144 |
22 | TAOK3 | 1.66642548 |
23 | GRK5 | 1.59997985 |
24 | CAMKK2 | 1.53402685 |
25 | PAK6 | 1.50688544 |
26 | PLK2 | 1.44377047 |
27 | DAPK2 | 1.38770616 |
28 | CDK5 | 1.36042048 |
29 | ERBB3 | 1.32902219 |
30 | WNK4 | 1.30941865 |
31 | SCYL2 | 1.30881899 |
32 | PHKG1 | 1.28085882 |
33 | PHKG2 | 1.28085882 |
34 | WNK3 | 1.26178599 |
35 | MAPK13 | 1.25982491 |
36 | NTRK2 | 1.24500102 |
37 | STK39 | 1.24396617 |
38 | KSR1 | 1.23685097 |
39 | BCR | 1.23511043 |
40 | MAP4K2 | 1.22484192 |
41 | EPHA4 | 1.22226769 |
42 | DYRK2 | 1.17847997 |
43 | FES | 1.17716553 |
44 | CSK | 1.17154081 |
45 | MAP3K13 | 1.16260481 |
46 | PIK3CG | 1.15574414 |
47 | TRIM28 | 1.15471018 |
48 | TYK2 | 1.14007273 |
49 | YES1 | 1.13675880 |
50 | CAMKK1 | 1.13533342 |
51 | MAP2K4 | 1.12765969 |
52 | EPHA3 | 1.09451482 |
53 | PAK3 | 1.08682861 |
54 | BTK | 1.07516930 |
55 | KIT | 1.07306395 |
56 | JAK3 | 1.06682296 |
57 | RET | 1.06653392 |
58 | SGK494 | 1.04733809 |
59 | SGK223 | 1.04733809 |
60 | CSF1R | 1.03098060 |
61 | CSNK1G2 | 1.01018713 |
62 | BMPR1B | 1.00216778 |
63 | PRKCE | 0.99904720 |
64 | LYN | 0.99431905 |
65 | JAK2 | 0.99334858 |
66 | HCK | 0.98378338 |
67 | MAP3K5 | 0.98290244 |
68 | PKN1 | 0.98027538 |
69 | FGR | 0.97929543 |
70 | SGK3 | 0.95143482 |
71 | BLK | 0.93147166 |
72 | NME1 | 0.86522097 |
73 | UHMK1 | 0.86491419 |
74 | CDK14 | 0.86034423 |
75 | JAK1 | 0.85765036 |
76 | TESK1 | 0.80877749 |
77 | CAMK2A | 0.80823841 |
78 | CAMK2B | 0.80687387 |
79 | BMPR2 | 0.80536448 |
80 | FRK | 0.79834244 |
81 | PRKCG | 0.79692751 |
82 | GRK7 | 0.79525089 |
83 | CSNK1G3 | 0.78459002 |
84 | TNIK | 0.78166994 |
85 | LMTK2 | 0.77717048 |
86 | EPHB1 | 0.76330026 |
87 | FER | 0.75664254 |
88 | MAP3K1 | 0.74970115 |
89 | PINK1 | 0.73451907 |
90 | CDK18 | 0.73212924 |
91 | GRK6 | 0.71688479 |
92 | CCNB1 | 0.70930912 |
93 | SIK2 | 0.70551795 |
94 | MST1R | 0.70037511 |
95 | CDK15 | 0.68838488 |
96 | DYRK1A | 0.67924892 |
97 | TGFBR2 | 0.67013716 |
98 | IRAK4 | 0.66571472 |
99 | PTK2B | 0.65202814 |
100 | DYRK1B | 0.64451231 |
101 | FYN | 0.63996445 |
102 | MAP4K1 | 0.63926509 |
103 | TBK1 | 0.63837260 |
104 | MAP2K1 | 0.63673645 |
105 | MARK2 | 0.63295923 |
106 | CDK19 | 0.61853945 |
107 | ROCK2 | 0.60500679 |
108 | LCK | 0.60399430 |
109 | DAPK1 | 0.59324875 |
110 | CAMK2D | 0.57998275 |
111 | SIK3 | 0.55794962 |
112 | MST4 | 0.54942672 |
113 | CSNK1A1L | 0.54785038 |
114 | MAP3K7 | 0.53984679 |
115 | STK3 | 0.53821978 |
116 | EGFR | 0.53819884 |
117 | CDK11A | 0.53334047 |
118 | ITK | 0.53296638 |
119 | IRAK1 | 0.53128875 |
120 | CAMK4 | 0.53049183 |
121 | PRKCZ | 0.53002950 |
122 | RPS6KA2 | 0.52084057 |
123 | PDPK1 | 0.52017482 |
124 | MAP3K14 | 0.50991967 |
125 | PRKD3 | 0.48748058 |
126 | SYK | 0.47439256 |
127 | PDK1 | 0.46681195 |
128 | IKBKE | 0.46461923 |
129 | ERBB2 | 0.46176804 |
130 | DYRK3 | 0.44879136 |
131 | PRPF4B | 0.44709016 |
132 | FGFR3 | 0.44603625 |
133 | CSNK1G1 | 0.44162522 |
134 | MATK | 0.42645335 |
135 | SGK1 | 0.42305479 |
136 | MAPKAPK5 | 0.42266866 |
137 | PRKCH | 0.42146186 |
138 | RAF1 | 0.41549937 |
139 | INSRR | 0.38070970 |
140 | SGK2 | 0.37931304 |
141 | PRKCD | 0.37741825 |
142 | MARK3 | 0.36527892 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.09948314 |
2 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.72281983 |
3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.27734281 |
4 | Nicotine addiction_Homo sapiens_hsa05033 | 2.23269275 |
5 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.15628011 |
6 | Asthma_Homo sapiens_hsa05310 | 2.09349032 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 1.98437501 |
8 | Allograft rejection_Homo sapiens_hsa05330 | 1.96176472 |
9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.93849110 |
10 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.93456905 |
11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.90207719 |
12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.81211356 |
13 | Morphine addiction_Homo sapiens_hsa05032 | 1.79287247 |
14 | Circadian entrainment_Homo sapiens_hsa04713 | 1.71597955 |
15 | Olfactory transduction_Homo sapiens_hsa04740 | 1.71380807 |
16 | Lysosome_Homo sapiens_hsa04142 | 1.69866074 |
17 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.68742828 |
18 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.63401667 |
19 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.61082447 |
20 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.59822333 |
21 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.56728643 |
22 | * Phagosome_Homo sapiens_hsa04145 | 1.52237065 |
23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.51966996 |
24 | Long-term potentiation_Homo sapiens_hsa04720 | 1.51176035 |
25 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.46974878 |
26 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.44717661 |
27 | Insulin secretion_Homo sapiens_hsa04911 | 1.42155899 |
28 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.40633084 |
29 | Salivary secretion_Homo sapiens_hsa04970 | 1.37634244 |
30 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.35217325 |
31 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.33899354 |
32 | Renin secretion_Homo sapiens_hsa04924 | 1.32675226 |
33 | Platelet activation_Homo sapiens_hsa04611 | 1.31458930 |
34 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.27818860 |
35 | Long-term depression_Homo sapiens_hsa04730 | 1.27745679 |
36 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.25651867 |
37 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.22570377 |
38 | Cocaine addiction_Homo sapiens_hsa05030 | 1.20309384 |
39 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.17911081 |
40 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.15875383 |
41 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.13626106 |
42 | * SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.13448088 |
43 | Viral myocarditis_Homo sapiens_hsa05416 | 1.11925562 |
44 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.11723544 |
45 | Taste transduction_Homo sapiens_hsa04742 | 1.11282286 |
46 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.10721550 |
47 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.07180663 |
48 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.05581499 |
49 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.05473936 |
50 | Axon guidance_Homo sapiens_hsa04360 | 1.03851112 |
51 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.01262856 |
52 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.98852934 |
53 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.96882201 |
54 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.95284737 |
55 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.95046002 |
56 | Gap junction_Homo sapiens_hsa04540 | 0.94820852 |
57 | Tuberculosis_Homo sapiens_hsa05152 | 0.94621728 |
58 | Alzheimers disease_Homo sapiens_hsa05010 | 0.93957205 |
59 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.93626388 |
60 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.92222705 |
61 | Endocytosis_Homo sapiens_hsa04144 | 0.91484205 |
62 | Pertussis_Homo sapiens_hsa05133 | 0.89700741 |
63 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.87529008 |
64 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.87074920 |
65 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.84844717 |
66 | Glioma_Homo sapiens_hsa05214 | 0.84802825 |
67 | Salmonella infection_Homo sapiens_hsa05132 | 0.84503996 |
68 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.80854183 |
69 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.79716975 |
70 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.79426308 |
71 | Influenza A_Homo sapiens_hsa05164 | 0.78506908 |
72 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.77808321 |
73 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.77629771 |
74 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.77422489 |
75 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.76447323 |
76 | Other glycan degradation_Homo sapiens_hsa00511 | 0.76117927 |
77 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.74861897 |
78 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.73833474 |
79 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.73663958 |
80 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.73554411 |
81 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.73011475 |
82 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.71889752 |
83 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.71322537 |
84 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.71270271 |
85 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.70893028 |
86 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.70202030 |
87 | Malaria_Homo sapiens_hsa05144 | 0.69595488 |
88 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.68791450 |
89 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.68724053 |
90 | Parkinsons disease_Homo sapiens_hsa05012 | 0.68460465 |
91 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.68354749 |
92 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.68268724 |
93 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.67977645 |
94 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.67177921 |
95 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.65084577 |
96 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.64642262 |
97 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.64451272 |
98 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.63948117 |
99 | Leishmaniasis_Homo sapiens_hsa05140 | 0.62924603 |
100 | Prion diseases_Homo sapiens_hsa05020 | 0.62524766 |
101 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.62303718 |
102 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.61774332 |
103 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.60918325 |
104 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.60181634 |
105 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.60116274 |
106 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.59927941 |
107 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.59838036 |
108 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.59227385 |
109 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.59079354 |
110 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.58116097 |
111 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.57494415 |
112 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.57184652 |
113 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.56123041 |
114 | Phototransduction_Homo sapiens_hsa04744 | 0.55989166 |
115 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.55927880 |
116 | Mineral absorption_Homo sapiens_hsa04978 | 0.55066185 |
117 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.54964168 |
118 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.54765152 |
119 | Melanogenesis_Homo sapiens_hsa04916 | 0.53836901 |
120 | Shigellosis_Homo sapiens_hsa05131 | 0.53499290 |
121 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.52769300 |
122 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.52411108 |
123 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.52083686 |
124 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.51966068 |
125 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.50027549 |
126 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.48779748 |
127 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.48432312 |
128 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.47063825 |
129 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.46071132 |
130 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45852173 |
131 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.45522620 |
132 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.45319215 |
133 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.45135622 |