STXBP4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lateral sprouting from an epithelium (GO:0060601)4.81398457
2regulation of non-canonical Wnt signaling pathway (GO:2000050)4.32628788
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.15379537
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.05631532
5epithelial cilium movement (GO:0003351)3.89691972
6histone H3-K4 trimethylation (GO:0080182)3.88053719
7negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.65537305
8negative regulation of translation, ncRNA-mediated (GO:0040033)3.65537305
9regulation of translation, ncRNA-mediated (GO:0045974)3.65537305
10mesenchymal-epithelial cell signaling (GO:0060638)3.63116264
11radial glial cell differentiation (GO:0060019)3.59640840
12interkinetic nuclear migration (GO:0022027)3.55203391
13replication fork processing (GO:0031297)3.51545175
14DNA double-strand break processing (GO:0000729)3.50318082
15mitotic sister chromatid cohesion (GO:0007064)3.44416850
16response to pheromone (GO:0019236)3.37755145
17cilium movement (GO:0003341)3.37548470
18regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.36732136
19cartilage morphogenesis (GO:0060536)3.33747891
20intraciliary transport (GO:0042073)3.32758643
21behavioral response to nicotine (GO:0035095)3.32403630
22cilium or flagellum-dependent cell motility (GO:0001539)3.31188053
23mesenchymal cell differentiation (GO:0048762)3.26573909
24somite development (GO:0061053)3.25521395
25cell proliferation involved in metanephros development (GO:0072203)3.21298779
26cell proliferation involved in kidney development (GO:0072111)3.17487134
27negative regulation of osteoblast proliferation (GO:0033689)3.11214124
28mesenchymal cell differentiation involved in kidney development (GO:0072161)3.10829607
29mesenchymal cell differentiation involved in renal system development (GO:2001012)3.10829607
30limb bud formation (GO:0060174)3.08141691
31protein polyglutamylation (GO:0018095)3.07369461
32cilium morphogenesis (GO:0060271)3.05547120
33detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.03968904
34cilium organization (GO:0044782)3.01840065
35kidney morphogenesis (GO:0060993)2.99939223
36cilium assembly (GO:0042384)2.98512241
37definitive hemopoiesis (GO:0060216)2.96873804
38lymphoid progenitor cell differentiation (GO:0002320)2.95450557
39somatic stem cell division (GO:0048103)2.93516032
40positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.92909405
41regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.92909405
42neural tube formation (GO:0001841)2.92481287
43regulation of cilium movement (GO:0003352)2.92409415
44head development (GO:0060322)2.92249865
45presynaptic membrane assembly (GO:0097105)2.91300396
46cell differentiation involved in metanephros development (GO:0072202)2.86835362
47kinetochore assembly (GO:0051382)2.84177980
48regulation of glucokinase activity (GO:0033131)2.83022684
49regulation of hexokinase activity (GO:1903299)2.83022684
50cranial nerve morphogenesis (GO:0021602)2.82196963
51water-soluble vitamin biosynthetic process (GO:0042364)2.81387267
52regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.80471730
53positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.80471730
54peptidyl-lysine trimethylation (GO:0018023)2.77557074
55regulation of somitogenesis (GO:0014807)2.77513422
56fucose catabolic process (GO:0019317)2.76135283
57L-fucose metabolic process (GO:0042354)2.76135283
58L-fucose catabolic process (GO:0042355)2.76135283
59respiratory chain complex IV assembly (GO:0008535)2.75898633
60pericardium development (GO:0060039)2.74836764
61regulation of DNA endoreduplication (GO:0032875)2.72946560
62hematopoietic stem cell proliferation (GO:0071425)2.72873556
63otic vesicle formation (GO:0030916)2.72845449
64specification of organ identity (GO:0010092)2.72515682
65somatic diversification of immune receptors via somatic mutation (GO:0002566)2.71747638
66somatic hypermutation of immunoglobulin genes (GO:0016446)2.71747638
67cranial nerve structural organization (GO:0021604)2.71482965
68regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.70926448
69tryptophan catabolic process (GO:0006569)2.70846926
70indole-containing compound catabolic process (GO:0042436)2.70846926
71indolalkylamine catabolic process (GO:0046218)2.70846926
72epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.70718153
73regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.70150846
74embryonic forelimb morphogenesis (GO:0035115)2.70123504
75negative regulation of stem cell proliferation (GO:2000647)2.68275722
76planar cell polarity pathway involved in neural tube closure (GO:0090179)2.66580291
77mesonephros development (GO:0001823)2.65343390
78cell differentiation involved in kidney development (GO:0061005)2.65339101
79platelet dense granule organization (GO:0060155)2.65070947
80cell migration involved in heart development (GO:0060973)2.64883893
81centriole replication (GO:0007099)2.64821583
82resolution of meiotic recombination intermediates (GO:0000712)2.64382847
83negative regulation of DNA-dependent DNA replication (GO:2000104)2.64204835
84kinetochore organization (GO:0051383)2.63480563
85synapsis (GO:0007129)2.62184921
86mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.61732540
87paraxial mesoderm development (GO:0048339)2.60773464
88facial nerve structural organization (GO:0021612)2.59888870
89regulation of pigment cell differentiation (GO:0050932)2.59707257
90axoneme assembly (GO:0035082)2.59324151
91regulation of centriole replication (GO:0046599)2.58687370
92protein K6-linked ubiquitination (GO:0085020)2.58436538
93recombinational repair (GO:0000725)2.58251173
94double-strand break repair via homologous recombination (GO:0000724)2.58219778
95embryonic camera-type eye morphogenesis (GO:0048596)2.58193730
96histone H3-K4 methylation (GO:0051568)2.58157619
97nephron tubule morphogenesis (GO:0072078)2.57732071
98nephron epithelium morphogenesis (GO:0072088)2.57732071
99photoreceptor cell maintenance (GO:0045494)2.57440821
100regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.56975557
101regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.56291455
102regulation of mitotic spindle checkpoint (GO:1903504)2.56291455
103regulation of smoothened signaling pathway (GO:0008589)2.54945873
104peptidyl-histidine modification (GO:0018202)2.53075513
105maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.52717083
106reflex (GO:0060004)2.52191981
107C4-dicarboxylate transport (GO:0015740)2.52050946
108smooth muscle tissue development (GO:0048745)2.51094457
109appendage development (GO:0048736)2.49742242
110limb development (GO:0060173)2.49742242
111convergent extension (GO:0060026)2.49639972
112indolalkylamine metabolic process (GO:0006586)2.49005703
113glomerulus development (GO:0032835)2.48604217
114reciprocal meiotic recombination (GO:0007131)2.47188573
115reciprocal DNA recombination (GO:0035825)2.47188573
116regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.46834627
117spinal cord motor neuron differentiation (GO:0021522)2.45310073
118tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.45221144
119RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.45221144
120kynurenine metabolic process (GO:0070189)2.45068390
121nonmotile primary cilium assembly (GO:0035058)2.44712661
122embryonic cranial skeleton morphogenesis (GO:0048701)2.44241481
123presynaptic membrane organization (GO:0097090)2.43178643
124embryonic digit morphogenesis (GO:0042733)2.42201286
125anatomical structure arrangement (GO:0048532)2.41265497
126embryonic limb morphogenesis (GO:0030326)2.40944281
127embryonic appendage morphogenesis (GO:0035113)2.40944281
128chromatin remodeling at centromere (GO:0031055)2.40472699
129microtubule anchoring (GO:0034453)2.40304565
130mesenchymal cell proliferation (GO:0010463)2.40239510
131cell proliferation in forebrain (GO:0021846)2.40081302
132regulation of nuclear cell cycle DNA replication (GO:0033262)2.39990148
133G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.39625302
134forelimb morphogenesis (GO:0035136)2.39215870
135smoothened signaling pathway (GO:0007224)2.38919611
136protein localization to cilium (GO:0061512)2.38072920
137axonemal dynein complex assembly (GO:0070286)2.38028405
138histone H2A acetylation (GO:0043968)2.37916109
139daunorubicin metabolic process (GO:0044597)2.37617595
140polyketide metabolic process (GO:0030638)2.37617595
141doxorubicin metabolic process (GO:0044598)2.37617595
142G-protein coupled receptor internalization (GO:0002031)2.37602070
143dorsal/ventral axis specification (GO:0009950)2.37039042
144negative regulation of chondrocyte differentiation (GO:0032331)2.36235276
145regulation of hippo signaling (GO:0035330)2.35768079
146regulation of telomere maintenance (GO:0032204)2.35559438
147appendage morphogenesis (GO:0035107)2.35528460
148limb morphogenesis (GO:0035108)2.35528460
149embryonic digestive tract morphogenesis (GO:0048557)2.35297418
150tryptophan metabolic process (GO:0006568)2.34989748
151cytochrome complex assembly (GO:0017004)2.34851847
152replicative senescence (GO:0090399)2.33935858
153hindbrain development (GO:0030902)2.32652349
154protein prenylation (GO:0018342)2.31907970
155prenylation (GO:0097354)2.31907970
156establishment of tissue polarity (GO:0007164)2.31282155
157establishment of planar polarity (GO:0001736)2.31282155
158venous blood vessel morphogenesis (GO:0048845)2.30860265
159cellular component assembly involved in morphogenesis (GO:0010927)2.30735663
160pharyngeal system development (GO:0060037)2.30666850
161positive regulation of heat generation (GO:0031652)2.29802741
162hindlimb morphogenesis (GO:0035137)2.29625614
163pituitary gland development (GO:0021983)2.29565277
164negative regulation of cytosolic calcium ion concentration (GO:0051481)2.28067269
165lymph node development (GO:0048535)2.26963671
166embryonic hindlimb morphogenesis (GO:0035116)2.26879867
167protein complex biogenesis (GO:0070271)2.26673364
168regulation of mesenchymal cell proliferation (GO:0010464)2.26594144
169cornea development in camera-type eye (GO:0061303)2.26453686
170cell morphogenesis involved in neuron differentiation (GO:0048667)2.26388712
171signal peptide processing (GO:0006465)2.25648754
172palate development (GO:0060021)2.25531670
173retinal ganglion cell axon guidance (GO:0031290)2.24999238
174nucleus localization (GO:0051647)2.24787232
175regulation of germinal center formation (GO:0002634)2.23486771
176mitochondrial respiratory chain complex assembly (GO:0033108)2.23193902
177regulation of centrosome duplication (GO:0010824)2.22988484
178regulation of meiosis I (GO:0060631)2.22514923
179histone exchange (GO:0043486)2.22042348
180pancreas development (GO:0031016)2.21990513
181CENP-A containing nucleosome assembly (GO:0034080)2.21873602
182positive regulation of granulocyte differentiation (GO:0030854)2.21847012
183artery development (GO:0060840)2.21671695
184determination of left/right symmetry (GO:0007368)2.20650130
185sperm motility (GO:0030317)2.20254883
186protein K11-linked deubiquitination (GO:0035871)2.20112213
187cellular ketone body metabolic process (GO:0046950)2.19711464
188mitochondrial RNA metabolic process (GO:0000959)2.19050015
189negative regulation of transcription regulatory region DNA binding (GO:2000678)2.16913194

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.63407844
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.79651882
3GBX2_23144817_ChIP-Seq_PC3_Human3.78590879
4TP63_19390658_ChIP-ChIP_HaCaT_Human3.76586257
5ZNF274_21170338_ChIP-Seq_K562_Hela3.05723698
6CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.82690460
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.60278555
8IGF1R_20145208_ChIP-Seq_DFB_Human2.56911050
9EZH2_22144423_ChIP-Seq_EOC_Human2.56532136
10VDR_22108803_ChIP-Seq_LS180_Human2.46529514
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.39023897
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.31328327
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.21922886
14EWS_26573619_Chip-Seq_HEK293_Human2.18780219
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.08393029
16* FUS_26573619_Chip-Seq_HEK293_Human1.99814697
17SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.92603072
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.92502593
19P300_19829295_ChIP-Seq_ESCs_Human1.91630943
20RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.87683307
21PCGF2_27294783_Chip-Seq_ESCs_Mouse1.86948652
22KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.86699940
23EED_16625203_ChIP-ChIP_MESCs_Mouse1.84848499
24PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.82769809
25PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.79729468
26SMAD_19615063_ChIP-ChIP_OVARY_Human1.76524326
27GABP_17652178_ChIP-ChIP_JURKAT_Human1.76328444
28SUZ12_27294783_Chip-Seq_NPCs_Mouse1.75285563
29SCL_19346495_ChIP-Seq_HPC-7_Human1.75279773
30TAF15_26573619_Chip-Seq_HEK293_Human1.70965924
31JARID2_20064375_ChIP-Seq_MESCs_Mouse1.70460840
32FLI1_27457419_Chip-Seq_LIVER_Mouse1.70074920
33NOTCH1_21737748_ChIP-Seq_TLL_Human1.70056499
34EZH2_27304074_Chip-Seq_ESCs_Mouse1.69483960
35ELK1_19687146_ChIP-ChIP_HELA_Human1.68784853
36BP1_19119308_ChIP-ChIP_Hs578T_Human1.68094354
37TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.68083441
38BMI1_23680149_ChIP-Seq_NPCS_Mouse1.67340462
39E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.67266884
40NFE2_27457419_Chip-Seq_LIVER_Mouse1.64509415
41SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.62858658
42CBX2_27304074_Chip-Seq_ESCs_Mouse1.62675611
43FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.61920561
44POU5F1_16153702_ChIP-ChIP_HESCs_Human1.60988339
45NANOG_18555785_Chip-Seq_ESCs_Mouse1.60969564
46EST1_17652178_ChIP-ChIP_JURKAT_Human1.60257180
47RNF2_27304074_Chip-Seq_NSC_Mouse1.56633177
48EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.56137850
49UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.56023096
50PIAS1_25552417_ChIP-Seq_VCAP_Human1.55785951
51E2F1_18555785_Chip-Seq_ESCs_Mouse1.55642404
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.54664532
53SMAD4_21799915_ChIP-Seq_A2780_Human1.53742202
54SALL1_21062744_ChIP-ChIP_HESCs_Human1.53691312
55CBP_20019798_ChIP-Seq_JUKART_Human1.51975259
56IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.51975259
57ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.51226345
58EZH2_27294783_Chip-Seq_NPCs_Mouse1.48386769
59* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.46625249
60SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45049395
61AR_21572438_ChIP-Seq_LNCaP_Human1.44028341
62POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.43987678
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43987678
64LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.43436081
65E2F4_17652178_ChIP-ChIP_JURKAT_Human1.41207479
66NR3C1_21868756_ChIP-Seq_MCF10A_Human1.41167643
67BCAT_22108803_ChIP-Seq_LS180_Human1.40726424
68PCGF2_27294783_Chip-Seq_NPCs_Mouse1.39978159
69CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.39073560
70P53_22387025_ChIP-Seq_ESCs_Mouse1.37778252
71* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.37767989
72CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.36051979
73STAT3_23295773_ChIP-Seq_U87_Human1.34780947
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.34415830
75SUZ12_18555785_Chip-Seq_ESCs_Mouse1.34152334
76SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.33632133
77SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.33202625
78* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.32417457
79HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.31688705
80RNF2_27304074_Chip-Seq_ESCs_Mouse1.30335054
81TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.29977765
82EZH2_18974828_ChIP-Seq_MESCs_Mouse1.29612866
83RNF2_18974828_ChIP-Seq_MESCs_Mouse1.29612866
84CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29247989
85MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.28932695
86CDX2_19796622_ChIP-Seq_MESCs_Mouse1.28241103
87STAT3_18555785_Chip-Seq_ESCs_Mouse1.27735183
88TCF4_22108803_ChIP-Seq_LS180_Human1.27360340
89MYC_18940864_ChIP-ChIP_HL60_Human1.27231575
90TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26762657
91ER_23166858_ChIP-Seq_MCF-7_Human1.23931125
92KLF5_20875108_ChIP-Seq_MESCs_Mouse1.22877547
93CMYC_18555785_Chip-Seq_ESCs_Mouse1.22585790
94* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.21887104
95* SMAD3_21741376_ChIP-Seq_EPCs_Human1.20982911
96SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.19829086
97WT1_19549856_ChIP-ChIP_CCG9911_Human1.19323454
98P300_18555785_Chip-Seq_ESCs_Mouse1.18975687
99JARID2_20075857_ChIP-Seq_MESCs_Mouse1.18510543
100* TCF4_23295773_ChIP-Seq_U87_Human1.16605508
101CTBP2_25329375_ChIP-Seq_LNCAP_Human1.15925996
102ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15922985
103OCT4_18555785_Chip-Seq_ESCs_Mouse1.15618385
104NMYC_18555785_Chip-Seq_ESCs_Mouse1.14967483
105EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.14663670
106IRF1_19129219_ChIP-ChIP_H3396_Human1.14275880
107TCF4_18268006_ChIP-ChIP_LS174T_Human1.14023144
108RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13830189
109TP53_22573176_ChIP-Seq_HFKS_Human1.11614199
110SOX2_18555785_Chip-Seq_ESCs_Mouse1.11048863
111CTBP1_25329375_ChIP-Seq_LNCAP_Human1.10687870
112SOX2_19829295_ChIP-Seq_ESCs_Human1.09497722
113NANOG_19829295_ChIP-Seq_ESCs_Human1.09497722
114AR_25329375_ChIP-Seq_VCAP_Human1.09340943
115TP53_18474530_ChIP-ChIP_U2OS_Human1.08971061
116RUNX1_27457419_Chip-Seq_LIVER_Mouse1.08802785
117* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.08407658
118* FLI1_21867929_ChIP-Seq_TH2_Mouse1.08187626
119CRX_20693478_ChIP-Seq_RETINA_Mouse1.08112015
120TAL1_26923725_Chip-Seq_HPCs_Mouse1.07358087
121SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.07153077
122PU1_27457419_Chip-Seq_LIVER_Mouse1.07123403
123GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06382114
124RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.06045801
125* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05451777
126TP53_16413492_ChIP-PET_HCT116_Human1.05275481
127* VDR_23849224_ChIP-Seq_CD4+_Human1.05054574
128RUNX2_22187159_ChIP-Seq_PCA_Human1.04698413
129CDX2_22108803_ChIP-Seq_LS180_Human1.04619245
130ZFX_18555785_Chip-Seq_ESCs_Mouse1.04127313
131* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03989225
132CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03778939
133PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02688844
134OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02264709
135SOX9_26525672_Chip-Seq_HEART_Mouse1.01533733
136SMAD4_21741376_ChIP-Seq_EPCs_Human1.00091833
137FOXM1_26456572_ChIP-Seq_MCF-7_Human1.00001075
138NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.98920036
139BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.96275179
140FOXA1_27270436_Chip-Seq_PROSTATE_Human0.94495510

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis4.52716212
2MP0006292_abnormal_olfactory_placode3.64930831
3MP0002938_white_spotting3.11926820
4MP0005409_darkened_coat_color2.77285307
5MP0002396_abnormal_hematopoietic_system2.68415594
6MP0005257_abnormal_intraocular_pressure2.62508443
7MP0003195_calcinosis2.56686465
8MP0000569_abnormal_digit_pigmentation2.50723250
9MP0001188_hyperpigmentation2.41180504
10MP0000049_abnormal_middle_ear2.35350824
11MP0010030_abnormal_orbit_morphology2.35035499
12MP0009250_abnormal_appendicular_skeleto2.33413129
13MP0003122_maternal_imprinting2.26252453
14MP0009780_abnormal_chondrocyte_physiolo2.14399281
15MP0002102_abnormal_ear_morphology2.08017303
16MP0005646_abnormal_pituitary_gland2.04767715
17MP0001293_anophthalmia2.02326480
18MP0002277_abnormal_respiratory_mucosa1.95157170
19MP0001299_abnormal_eye_distance/1.89752499
20MP0002249_abnormal_larynx_morphology1.87365284
21MP0005253_abnormal_eye_physiology1.84470645
22MP0003121_genomic_imprinting1.83778022
23MP0002234_abnormal_pharynx_morphology1.82397572
24MP0003880_abnormal_central_pattern1.73450674
25MP0003890_abnormal_embryonic-extraembry1.67644442
26MP0003937_abnormal_limbs/digits/tail_de1.62586904
27MP0004808_abnormal_hematopoietic_stem1.60219377
28MP0008995_early_reproductive_senescence1.58385545
29MP0005503_abnormal_tendon_morphology1.57326155
30MP0002837_dystrophic_cardiac_calcinosis1.54486969
31MP0001346_abnormal_lacrimal_gland1.52161377
32MP0003385_abnormal_body_wall1.50570132
33MP0000631_abnormal_neuroendocrine_gland1.46756681
34MP0001485_abnormal_pinna_reflex1.45949591
35MP0002116_abnormal_craniofacial_bone1.45920514
36MP0003787_abnormal_imprinting1.44707653
37MP0002177_abnormal_outer_ear1.40218019
38MP0005174_abnormal_tail_pigmentation1.39807042
39MP0000428_abnormal_craniofacial_morphol1.38878679
40MP0001529_abnormal_vocalization1.38352367
41MP0008058_abnormal_DNA_repair1.37844656
42MP0000427_abnormal_hair_cycle1.37340022
43MP0009046_muscle_twitch1.36481057
44MP0002095_abnormal_skin_pigmentation1.36257960
45MP0003755_abnormal_palate_morphology1.33861014
46MP0009697_abnormal_copulation1.32330756
47MP0003938_abnormal_ear_development1.32119123
48MP0002160_abnormal_reproductive_system1.31212097
49MP0008877_abnormal_DNA_methylation1.30565677
50MP0003136_yellow_coat_color1.29762816
51MP0002876_abnormal_thyroid_physiology1.29290113
52MP0003935_abnormal_craniofacial_develop1.29083085
53MP0002109_abnormal_limb_morphology1.29038259
54MP0002233_abnormal_nose_morphology1.28562869
55MP0006276_abnormal_autonomic_nervous1.27272374
56MP0005075_abnormal_melanosome_morpholog1.27085097
57MP0010368_abnormal_lymphatic_system1.26862609
58MP0005171_absent_coat_pigmentation1.25808180
59MP0003942_abnormal_urinary_system1.24141903
60MP0005645_abnormal_hypothalamus_physiol1.23293732
61MP0003718_maternal_effect1.23278176
62MP0000383_abnormal_hair_follicle1.22490494
63MP0000647_abnormal_sebaceous_gland1.21402922
64MP0000432_abnormal_head_morphology1.19717273
65MP0002932_abnormal_joint_morphology1.19380292
66MP0003941_abnormal_skin_development1.19024645
67MP0002653_abnormal_ependyma_morphology1.16012745
68MP0005248_abnormal_Harderian_gland1.14186956
69MP0003943_abnormal_hepatobiliary_system1.11527562
70MP0003119_abnormal_digestive_system1.10499258
71MP0001968_abnormal_touch/_nociception1.09579796
72MP0005389_reproductive_system_phenotype1.09530706
73MP0005508_abnormal_skeleton_morphology1.07186669
74MP0002736_abnormal_nociception_after1.06095165
75MP0003828_pulmonary_edema1.03820496
76MP0000015_abnormal_ear_pigmentation1.03510501
77MP0004142_abnormal_muscle_tone1.03330150
78MP0008057_abnormal_DNA_replication1.02995350
79MP0005379_endocrine/exocrine_gland_phen1.02611924
80MP0000778_abnormal_nervous_system1.02058001
81MP0002697_abnormal_eye_size1.01955698
82MP0002163_abnormal_gland_morphology1.00738088
83MP0008007_abnormal_cellular_replicative1.00726325
84MP0003786_premature_aging1.00425024
85MP0005195_abnormal_posterior_eye1.00132870
86MP0004215_abnormal_myocardial_fiber0.99971152
87MP0003567_abnormal_fetal_cardiomyocyte0.97494824
88MP0009384_cardiac_valve_regurgitation0.97157860
89MP0002114_abnormal_axial_skeleton0.97003292
90MP0002075_abnormal_coat/hair_pigmentati0.96924622
91MP0004043_abnormal_pH_regulation0.96654276
92MP0005084_abnormal_gallbladder_morpholo0.95343023
93MP0001929_abnormal_gametogenesis0.95211713
94MP0002557_abnormal_social/conspecific_i0.95166760
95MP0001286_abnormal_eye_development0.95069768
96MP0008872_abnormal_physiological_respon0.93354503
97MP0004134_abnormal_chest_morphology0.92784551
98MP0005499_abnormal_olfactory_system0.92141425
99MP0005394_taste/olfaction_phenotype0.92141425
100MP0004885_abnormal_endolymph0.91888194
101MP0002113_abnormal_skeleton_development0.91750272
102MP0002928_abnormal_bile_duct0.91602656
103MP0003283_abnormal_digestive_organ0.91118505
104MP0002184_abnormal_innervation0.91024323
105MP0001986_abnormal_taste_sensitivity0.90222983
106MP0003698_abnormal_male_reproductive0.88410124
107MP0000762_abnormal_tongue_morphology0.87785649
108MP0003315_abnormal_perineum_morphology0.87642641
109MP0000534_abnormal_ureter_morphology0.87066317
110MP0000681_abnormal_thyroid_gland0.86499259
111MP0002210_abnormal_sex_determination0.84903126
112MP0008789_abnormal_olfactory_epithelium0.84859322
113MP0001879_abnormal_lymphatic_vessel0.84108987
114MP0002638_abnormal_pupillary_reflex0.83812481
115MP0000163_abnormal_cartilage_morphology0.83734616
116MP0009745_abnormal_behavioral_response0.83671545
117MP0000613_abnormal_salivary_gland0.83496747
118MP0002752_abnormal_somatic_nervous0.83289219
119MP0002272_abnormal_nervous_system0.83274196
120MP0000653_abnormal_sex_gland0.83110870
121MP0005187_abnormal_penis_morphology0.82769747
122MP0001984_abnormal_olfaction0.82041000
123MP0000372_irregular_coat_pigmentation0.81242638
124MP0005551_abnormal_eye_electrophysiolog0.81100597
125MP0010678_abnormal_skin_adnexa0.81011111
126MP0000678_abnormal_parathyroid_gland0.80797426
127MP0009703_decreased_birth_body0.80287132
128MP0002115_abnormal_skeleton_extremities0.79291194
129MP0000026_abnormal_inner_ear0.79212165
130MP0005391_vision/eye_phenotype0.78862607
131MP0010094_abnormal_chromosome_stability0.78607404
132MP0010386_abnormal_urinary_bladder0.76965625
133MP0001145_abnormal_male_reproductive0.76842032
134MP0002282_abnormal_trachea_morphology0.76364536
135MP0001486_abnormal_startle_reflex0.76304417
136MP0005220_abnormal_exocrine_pancreas0.76275002
137MP0001919_abnormal_reproductive_system0.75340312
138MP0001186_pigmentation_phenotype0.74409479
139MP0001270_distended_abdomen0.74190089
140MP0004145_abnormal_muscle_electrophysio0.73849733
141MP0000516_abnormal_urinary_system0.73651196
142MP0005367_renal/urinary_system_phenotyp0.73651196
143MP0004133_heterotaxia0.73511424
144MP0005197_abnormal_uvea_morphology0.73409929
145MP0003868_abnormal_feces_composition0.73087739
146MP0001119_abnormal_female_reproductive0.73009288
147MP0002751_abnormal_autonomic_nervous0.72663538
148MP0002108_abnormal_muscle_morphology0.72371703
149MP0001324_abnormal_eye_pigmentation0.72104859
150MP0000579_abnormal_nail_morphology0.71840741
151MP0006072_abnormal_retinal_apoptosis0.70522972
152MP0002092_abnormal_eye_morphology0.70057979

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the parietal bone (HP:0002696)4.12573155
2Midline defect of the nose (HP:0004122)3.90908892
3White forelock (HP:0002211)3.23900598
4Patchy hypopigmentation of hair (HP:0011365)3.23619562
5Abnormality of the nasal septum (HP:0000419)3.10436421
6Chromsome breakage (HP:0040012)2.86727959
7Nasolacrimal duct obstruction (HP:0000579)2.85511577
8Short middle phalanx of the 5th finger (HP:0004220)2.84776349
9Abnormality of the columella (HP:0009929)2.84728980
10Trigonocephaly (HP:0000243)2.82748608
11Abnormality of the renal cortex (HP:0011035)2.77640847
12Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.71896112
13Short 4th metacarpal (HP:0010044)2.71896112
14Chromosomal breakage induced by crosslinking agents (HP:0003221)2.70771532
15Pancreatic fibrosis (HP:0100732)2.67298911
16Abnormality of incisor morphology (HP:0011063)2.65479412
17True hermaphroditism (HP:0010459)2.60433529
18Congenital primary aphakia (HP:0007707)2.54530807
19Genital tract atresia (HP:0001827)2.51984358
20Gait imbalance (HP:0002141)2.50003661
21Abnormality of the right ventricle (HP:0001707)2.49497116
22Abnormality of the lacrimal duct (HP:0011481)2.49484689
23Aplasia/Hypoplasia of the uvula (HP:0010293)2.47133329
24Abnormality of the incisor (HP:0000676)2.46860874
25Vaginal atresia (HP:0000148)2.40585498
26Abnormality of the nasolacrimal system (HP:0000614)2.40397162
27Abnormality of the labia minora (HP:0012880)2.39366805
28Renal cortical cysts (HP:0000803)2.38632123
29Sclerocornea (HP:0000647)2.38494128
30Ectopic kidney (HP:0000086)2.37322563
31Increased number of teeth (HP:0011069)2.37287252
32Optic nerve hypoplasia (HP:0000609)2.34254669
33Abnormal number of incisors (HP:0011064)2.34162788
34Nephrogenic diabetes insipidus (HP:0009806)2.34032458
35Absent/shortened dynein arms (HP:0200106)2.33409801
36Dynein arm defect of respiratory motile cilia (HP:0012255)2.33409801
37Type II lissencephaly (HP:0007260)2.30561031
38Aplasia/Hypoplasia of the tongue (HP:0010295)2.29853217
39Aplasia cutis congenita (HP:0001057)2.29112795
40Chronic hepatic failure (HP:0100626)2.29110009
41Preaxial hand polydactyly (HP:0001177)2.28605998
42Gastrointestinal atresia (HP:0002589)2.27606459
43Aplasia/Hypoplasia of the tibia (HP:0005772)2.27573438
44Volvulus (HP:0002580)2.27170888
45Acute lymphatic leukemia (HP:0006721)2.26757622
46Tubular atrophy (HP:0000092)2.26119495
47Bile duct proliferation (HP:0001408)2.24648283
48Abnormal biliary tract physiology (HP:0012439)2.24648283
49Hyperventilation (HP:0002883)2.24163738
50Abnormality of the ileum (HP:0001549)2.22924883
51Meckel diverticulum (HP:0002245)2.22794230
52Postaxial hand polydactyly (HP:0001162)2.19801131
53Colon cancer (HP:0003003)2.19062626
54Median cleft lip (HP:0000161)2.17719467
55Male pseudohermaphroditism (HP:0000037)2.17636090
56Lip pit (HP:0100267)2.16493479
57Abnormality of chromosome stability (HP:0003220)2.16464581
58Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.14713008
59Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.13482999
60Abolished electroretinogram (ERG) (HP:0000550)2.12057816
61Microglossia (HP:0000171)2.11557649
62Abnormality of the fingertips (HP:0001211)2.11475148
63Cerebellar dysplasia (HP:0007033)2.10575197
64Decreased lacrimation (HP:0000633)2.10545862
65Optic nerve coloboma (HP:0000588)2.10172787
66Stomach cancer (HP:0012126)2.09957016
67Congenital hepatic fibrosis (HP:0002612)2.07527987
68Hypothermia (HP:0002045)2.06576996
69Pancreatic cysts (HP:0001737)2.06537391
70Pendular nystagmus (HP:0012043)2.06534096
71Long eyelashes (HP:0000527)2.04952411
72Poor coordination (HP:0002370)2.03421384
73Narrow palate (HP:0000189)2.02448202
74Bell-shaped thorax (HP:0001591)2.01848662
75Furrowed tongue (HP:0000221)2.01815350
76Abnormal respiratory motile cilium morphology (HP:0005938)2.01564638
77Abnormal respiratory epithelium morphology (HP:0012253)2.01564638
78Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.01162998
79Increased corneal curvature (HP:0100692)2.00864236
80Keratoconus (HP:0000563)2.00864236
81Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.00393991
82Congenital stationary night blindness (HP:0007642)1.98717017
83Alacrima (HP:0000522)1.97771881
84Chorioretinal atrophy (HP:0000533)1.95696662
85Cutaneous syndactyly (HP:0012725)1.95370968
86Smooth philtrum (HP:0000319)1.94230300
87Prostate neoplasm (HP:0100787)1.93670754
88Cutaneous finger syndactyly (HP:0010554)1.91895949
89Sloping forehead (HP:0000340)1.91319922
90Partial duplication of the phalanx of hand (HP:0009999)1.89962839
91Abnormal respiratory motile cilium physiology (HP:0012261)1.89155435
92Polydipsia (HP:0001959)1.88601152
93Abnormal drinking behavior (HP:0030082)1.88601152
94Oligodactyly (hands) (HP:0001180)1.88151409
95Thyroid-stimulating hormone excess (HP:0002925)1.87907836
96Partial duplication of thumb phalanx (HP:0009944)1.87317099
97Congenital sensorineural hearing impairment (HP:0008527)1.86982357
98Tubulointerstitial nephritis (HP:0001970)1.85965236
99Depressed nasal tip (HP:0000437)1.85479209
100Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.85370327
101Supernumerary ribs (HP:0005815)1.84765790
102Short tibia (HP:0005736)1.84468859
103Cystic liver disease (HP:0006706)1.83317601
104Acute myeloid leukemia (HP:0004808)1.82657798
105Spinal cord lesions (HP:0100561)1.82203325
106Syringomyelia (HP:0003396)1.82203325
107Gaze-evoked nystagmus (HP:0000640)1.81743554
108Widely spaced teeth (HP:0000687)1.81735288
109Dandy-Walker malformation (HP:0001305)1.81125006
110Small hand (HP:0200055)1.80985711
111Duplication of thumb phalanx (HP:0009942)1.79685720
112Esophageal atresia (HP:0002032)1.79628058
113Molar tooth sign on MRI (HP:0002419)1.79357639
114Abnormality of midbrain morphology (HP:0002418)1.79357639
115Febrile seizures (HP:0002373)1.79168218
116Postaxial foot polydactyly (HP:0001830)1.78915165
117Aganglionic megacolon (HP:0002251)1.77430858
118Abnormality of the renal medulla (HP:0100957)1.77319744
119Abnormality of the phalanges of the 5th finger (HP:0004213)1.77232344
120Mesomelia (HP:0003027)1.76912664
121Astigmatism (HP:0000483)1.76321422
122Anophthalmia (HP:0000528)1.74527348
123Lissencephaly (HP:0001339)1.74471044
124Abnormality of the diencephalon (HP:0010662)1.73898754
125Narrow forehead (HP:0000341)1.73417029
126Methylmalonic acidemia (HP:0002912)1.73240451
127Abnormality of the phalanges of the hallux (HP:0010057)1.73231837
128Aqueductal stenosis (HP:0002410)1.73173479
129Anencephaly (HP:0002323)1.72934259
130Abnormality of molar (HP:0011077)1.72659430
131Abnormality of molar morphology (HP:0011070)1.72659430
132Nephronophthisis (HP:0000090)1.72462300
133Anal stenosis (HP:0002025)1.72127936
134Aplasia of the phalanges of the hand (HP:0009802)1.72090221
135Aplasia involving bones of the extremities (HP:0009825)1.72090221
136Aplasia involving bones of the upper limbs (HP:0009823)1.72090221
137Abnormal ciliary motility (HP:0012262)1.71371436
138Renal hypoplasia (HP:0000089)1.70562051
139Occipital encephalocele (HP:0002085)1.70211813
140Supernumerary bones of the axial skeleton (HP:0009144)1.70193184
141Abnormality of the 4th metacarpal (HP:0010012)1.70068580
142Attenuation of retinal blood vessels (HP:0007843)1.69926156
143Hyperglycinemia (HP:0002154)1.69778953
144Abnormal rod and cone electroretinograms (HP:0008323)1.68261505
145Acute necrotizing encephalopathy (HP:0006965)1.66988406
146Intestinal atresia (HP:0011100)1.66823976
147Hypoplasia of the pons (HP:0012110)1.66552984
148Renal dysplasia (HP:0000110)1.65971775
149Abnormality of the dental root (HP:0006486)1.65863512
150Taurodontia (HP:0000679)1.65863512
151Abnormality of permanent molar morphology (HP:0011071)1.65863512
152Myelomeningocele (HP:0002475)1.65860407
153Hemiparesis (HP:0001269)1.65246856
154Septo-optic dysplasia (HP:0100842)1.65201820
155Prominent nasal bridge (HP:0000426)1.65093389
156Oligohydramnios (HP:0001562)1.64797018
157Bifid tongue (HP:0010297)1.64619171
158Deep philtrum (HP:0002002)1.64499743
159Rhinitis (HP:0012384)1.64443592
160Hypomagnesemia (HP:0002917)1.64351237
161Acute encephalopathy (HP:0006846)1.63862271
162Abnormality of the phalanges of the 2nd finger (HP:0009541)1.63544838
163Abnormality of the duodenum (HP:0002246)1.63535924
164Medial flaring of the eyebrow (HP:0010747)1.63427292
165Increased nuchal translucency (HP:0010880)1.63058460
166Abnormality of the intervertebral disk (HP:0005108)1.62639596
167Renal duplication (HP:0000075)1.61721890
168Supernumerary spleens (HP:0009799)1.61314204
169Oculomotor apraxia (HP:0000657)1.60816012
170Morphological abnormality of the middle ear (HP:0008609)1.59911717
171Abnormality of the renal collecting system (HP:0004742)1.59563448
172Absent eyebrow (HP:0002223)1.58299020

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.96674746
2SIK33.96696763
3TNIK3.44950033
4MAP4K22.90959896
5ZAK2.89157033
6CDK82.87262426
7CASK2.31287828
8BRD42.29391857
9CDK122.27214083
10LATS12.18382571
11INSRR2.13135282
12TRIM282.06848624
13PINK12.05012524
14ACVR1B2.04366147
15CAMK1D2.03852942
16CAMK1G2.02232132
17PNCK1.97250122
18TGFBR21.93896994
19CDK31.93340678
20NUAK11.91157789
21MUSK1.88751831
22STK391.82588636
23SIK11.79194984
24MKNK11.76124429
25MAP3K41.75330862
26WNK41.74638508
27MKNK21.72998945
28TEC1.71532096
29ADRBK21.70933664
30BMPR1B1.61991135
31MAPK151.52667701
32VRK11.50530149
33WEE11.48221222
34EIF2AK31.47349237
35MAPK131.44359822
36EIF2AK21.42375890
37SRPK11.42369072
38CDC71.38545398
39MAP2K71.37760454
40GRK71.35562750
41STK161.35209625
42OXSR11.33646622
43SIK21.31470596
44KIT1.30265745
45DMPK1.27422200
46MST41.26072476
47PBK1.25341824
48YES11.25327609
49ATR1.24363067
50SGK21.21100574
51PAK31.18560879
52MAPKAPK31.17363290
53OBSCN1.17049684
54BCR1.16526896
55CSNK1G11.15611461
56RPS6KA41.13068621
57NEK11.12301901
58CCNB11.11595895
59NLK1.08045788
60PIK3CA1.08029869
61TXK1.05481277
62CAMK11.02885152
63NEK61.01937554
64ERBB30.98867403
65TLK10.97760386
66CDK70.97280561
67BUB10.97273350
68CSNK1G20.96392322
69CHEK20.95372424
70EPHA30.89259485
71CSNK1G30.88812059
72FLT30.88097146
73TAOK30.87927806
74CSF1R0.87917999
75DYRK20.84121533
76EPHA40.83896641
77CAMK40.83491932
78PLK40.81614976
79TTK0.81376348
80FGFR20.80913712
81PLK10.80730069
82DYRK30.79090031
83TSSK60.78194286
84TNK20.77684192
85TIE10.77130774
86MAPK70.76545012
87BRSK20.74358180
88PLK30.72880114
89SGK30.72056990
90EIF2AK10.69958269
91PRKCG0.69783935
92NEK20.68952973
93TGFBR10.68558178
94CAMKK20.67788318
95HIPK20.65757624
96BTK0.65098612
97MAPKAPK50.64525273
98CDK90.62425974
99BRSK10.61508167
100MARK20.60788572
101RPS6KA50.60056302
102PRKAA20.59752211
103NTRK30.59529337
104IRAK40.59260729
105MAP3K130.58276367
106FER0.56575874
107ATM0.56188705
108TRPM70.56171566
109MARK10.53454525
110CHUK0.52325511
111PLK20.51309622
112ITK0.51149976
113GRK10.51043761
114IRAK10.50325266
115ADRBK10.48996110
116EEF2K0.47950451
117PRKCE0.47876126
118TAF10.47198302
119MAPK140.44994337
120PHKG20.43860926
121PHKG10.43860926
122ERBB20.43583430
123ERBB40.43073676
124VRK20.43038748
125STK30.42771516
126NME10.42594674
127CDK60.42004210
128PRKAA10.41825236
129STK38L0.40568673
130WNK10.40249269
131FGFR10.40105587
132FGFR30.39985788
133PRKG10.39749251
134MAP3K60.39731807
135LYN0.38579327
136SGK2230.37410465
137SGK4940.37410465
138NEK90.37347027
139CSNK1D0.36839402
140CSNK1A10.36216037
141AKT30.35450122
142CDK10.34740217
143BCKDK0.34595485
144MET0.34302879
145MAPKAPK20.34165726
146PTK2B0.33419708
147WNK30.31665451
148CSNK1A1L0.31298374
149AURKB0.31050975
150GSK3B0.30694695
151CAMK2A0.29249196

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030602.74430165
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.70320720
3Basal cell carcinoma_Homo sapiens_hsa052172.27359042
4Fanconi anemia pathway_Homo sapiens_hsa034602.25717859
5Butanoate metabolism_Homo sapiens_hsa006502.21241392
6Maturity onset diabetes of the young_Homo sapiens_hsa049502.10740608
7Propanoate metabolism_Homo sapiens_hsa006402.08976111
8Homologous recombination_Homo sapiens_hsa034402.08754043
9RNA polymerase_Homo sapiens_hsa030202.05467883
10Selenocompound metabolism_Homo sapiens_hsa004501.98547517
11Steroid biosynthesis_Homo sapiens_hsa001001.90083791
12Basal transcription factors_Homo sapiens_hsa030221.86099979
13Phototransduction_Homo sapiens_hsa047441.84662183
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.82163206
15Transcriptional misregulation in cancer_Homo sapiens_hsa052021.81463896
16Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.79744025
17Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.75330020
18Oxidative phosphorylation_Homo sapiens_hsa001901.64229152
19Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.60922378
20Non-homologous end-joining_Homo sapiens_hsa034501.60489036
21Nitrogen metabolism_Homo sapiens_hsa009101.58484264
22Hedgehog signaling pathway_Homo sapiens_hsa043401.58364384
23One carbon pool by folate_Homo sapiens_hsa006701.58197719
24Wnt signaling pathway_Homo sapiens_hsa043101.58183999
25Circadian rhythm_Homo sapiens_hsa047101.58084417
26RNA degradation_Homo sapiens_hsa030181.55418688
27Cell cycle_Homo sapiens_hsa041101.55255725
28Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.52870657
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.48993907
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.42705197
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.39896135
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.31565668
33Tryptophan metabolism_Homo sapiens_hsa003801.30977022
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.30318341
35Melanoma_Homo sapiens_hsa052181.24325221
36Parkinsons disease_Homo sapiens_hsa050121.22909805
37Notch signaling pathway_Homo sapiens_hsa043301.22064616
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.22061799
39Linoleic acid metabolism_Homo sapiens_hsa005911.21841258
40Nicotine addiction_Homo sapiens_hsa050331.21655975
41Peroxisome_Homo sapiens_hsa041461.20776318
42Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.17202396
43Herpes simplex infection_Homo sapiens_hsa051681.17033465
44Adherens junction_Homo sapiens_hsa045201.16737241
45NF-kappa B signaling pathway_Homo sapiens_hsa040641.14811668
46Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.14634364
47Spliceosome_Homo sapiens_hsa030401.14224902
48Huntingtons disease_Homo sapiens_hsa050161.12618341
49Mismatch repair_Homo sapiens_hsa034301.12219385
50Colorectal cancer_Homo sapiens_hsa052101.12078270
51DNA replication_Homo sapiens_hsa030301.11942683
52Pathways in cancer_Homo sapiens_hsa052001.10872810
53Ether lipid metabolism_Homo sapiens_hsa005651.09983377
54RNA transport_Homo sapiens_hsa030131.09074191
55alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.08424732
56Steroid hormone biosynthesis_Homo sapiens_hsa001401.07916118
57Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.07858527
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.06055613
59Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.04969553
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04139609
61MicroRNAs in cancer_Homo sapiens_hsa052061.02656060
62Sulfur metabolism_Homo sapiens_hsa009201.01903979
63Proteasome_Homo sapiens_hsa030501.00943199
64Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.99846842
65Chemical carcinogenesis_Homo sapiens_hsa052040.99826931
66mRNA surveillance pathway_Homo sapiens_hsa030150.99644198
67TGF-beta signaling pathway_Homo sapiens_hsa043500.99413839
68Base excision repair_Homo sapiens_hsa034100.98535955
69Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.98028880
70Hippo signaling pathway_Homo sapiens_hsa043900.97804293
71Retinol metabolism_Homo sapiens_hsa008300.97618868
72Prostate cancer_Homo sapiens_hsa052150.97266051
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.96944439
74Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.96885390
75Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.96217075
76cAMP signaling pathway_Homo sapiens_hsa040240.96150634
77Vitamin B6 metabolism_Homo sapiens_hsa007500.94742215
78HTLV-I infection_Homo sapiens_hsa051660.93800283
79Nucleotide excision repair_Homo sapiens_hsa034200.93524400
80Circadian entrainment_Homo sapiens_hsa047130.90382940
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89823943
82Chronic myeloid leukemia_Homo sapiens_hsa052200.89329264
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87870951
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.86782633
85Hematopoietic cell lineage_Homo sapiens_hsa046400.86682829
86Calcium signaling pathway_Homo sapiens_hsa040200.85770816
87SNARE interactions in vesicular transport_Homo sapiens_hsa041300.85077843
88Lysine degradation_Homo sapiens_hsa003100.84918164
89Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84770973
90Toll-like receptor signaling pathway_Homo sapiens_hsa046200.83957697
91Taste transduction_Homo sapiens_hsa047420.83451146
92beta-Alanine metabolism_Homo sapiens_hsa004100.83212923
93Pancreatic cancer_Homo sapiens_hsa052120.83056750
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.82958973
95Caffeine metabolism_Homo sapiens_hsa002320.82428502
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.81153101
97Hepatitis B_Homo sapiens_hsa051610.79303624
98Folate biosynthesis_Homo sapiens_hsa007900.78860019
99p53 signaling pathway_Homo sapiens_hsa041150.78779152
100Fatty acid degradation_Homo sapiens_hsa000710.78612812
101Cysteine and methionine metabolism_Homo sapiens_hsa002700.77485697
102Dilated cardiomyopathy_Homo sapiens_hsa054140.77237631
103Thyroid hormone signaling pathway_Homo sapiens_hsa049190.77126061
104Pyrimidine metabolism_Homo sapiens_hsa002400.76865358
105Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.76546786
106Melanogenesis_Homo sapiens_hsa049160.76491338
107Morphine addiction_Homo sapiens_hsa050320.76204636
108ABC transporters_Homo sapiens_hsa020100.75810866
109Fatty acid metabolism_Homo sapiens_hsa012120.75095323
110Axon guidance_Homo sapiens_hsa043600.74649211
111Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74361006
112Serotonergic synapse_Homo sapiens_hsa047260.73753346
113Prolactin signaling pathway_Homo sapiens_hsa049170.73550707
114Rap1 signaling pathway_Homo sapiens_hsa040150.73534781
115Metabolic pathways_Homo sapiens_hsa011000.73039169
116Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72729021
117Alzheimers disease_Homo sapiens_hsa050100.72061851
118Cocaine addiction_Homo sapiens_hsa050300.71833012
119Small cell lung cancer_Homo sapiens_hsa052220.71795611
120Fat digestion and absorption_Homo sapiens_hsa049750.71779626
121PI3K-Akt signaling pathway_Homo sapiens_hsa041510.71398196
122Amphetamine addiction_Homo sapiens_hsa050310.70799835
123Acute myeloid leukemia_Homo sapiens_hsa052210.70475931
124Olfactory transduction_Homo sapiens_hsa047400.69895816
125Ras signaling pathway_Homo sapiens_hsa040140.69346945
126Measles_Homo sapiens_hsa051620.68275039
127Aldosterone synthesis and secretion_Homo sapiens_hsa049250.67760478
128Ovarian steroidogenesis_Homo sapiens_hsa049130.66323811
129Osteoclast differentiation_Homo sapiens_hsa043800.66203718
130Glutamatergic synapse_Homo sapiens_hsa047240.64881894
131Glycerolipid metabolism_Homo sapiens_hsa005610.63593739
132Vitamin digestion and absorption_Homo sapiens_hsa049770.63553565
133Insulin secretion_Homo sapiens_hsa049110.63440114
134Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.63296243
135cGMP-PKG signaling pathway_Homo sapiens_hsa040220.63042280
136Renin secretion_Homo sapiens_hsa049240.62832336
137Primary immunodeficiency_Homo sapiens_hsa053400.62655987
138GABAergic synapse_Homo sapiens_hsa047270.62203379
139Sphingolipid metabolism_Homo sapiens_hsa006000.61665261
140MAPK signaling pathway_Homo sapiens_hsa040100.61400050
141AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.60737013
142FoxO signaling pathway_Homo sapiens_hsa040680.60562656
143Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60457681
144ErbB signaling pathway_Homo sapiens_hsa040120.60445427
145Cholinergic synapse_Homo sapiens_hsa047250.59323966
146Oxytocin signaling pathway_Homo sapiens_hsa049210.58787399
147Oocyte meiosis_Homo sapiens_hsa041140.58677442
148B cell receptor signaling pathway_Homo sapiens_hsa046620.57591065
149RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.57524246
150Purine metabolism_Homo sapiens_hsa002300.57190909
151Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56383772
152Fatty acid elongation_Homo sapiens_hsa000620.56202479
153Proteoglycans in cancer_Homo sapiens_hsa052050.55382311
154Platelet activation_Homo sapiens_hsa046110.55082519
155Regulation of autophagy_Homo sapiens_hsa041400.54066628
156Pyruvate metabolism_Homo sapiens_hsa006200.54057152
157Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53707609
158Choline metabolism in cancer_Homo sapiens_hsa052310.53300886
159Influenza A_Homo sapiens_hsa051640.52932923
160Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.52291599
161Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.49154697
162Fatty acid biosynthesis_Homo sapiens_hsa000610.46114171
163Cardiac muscle contraction_Homo sapiens_hsa042600.45621776

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