SUB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.04975793
2energy coupled proton transport, down electrochemical gradient (GO:0015985)5.61011324
3ATP synthesis coupled proton transport (GO:0015986)5.61011324
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.92115047
5establishment of protein localization to mitochondrial membrane (GO:0090151)4.69420397
6protein neddylation (GO:0045116)4.50025018
7chaperone-mediated protein transport (GO:0072321)4.44603459
8CENP-A containing nucleosome assembly (GO:0034080)4.39749293
9respiratory electron transport chain (GO:0022904)4.33659613
10chromatin remodeling at centromere (GO:0031055)4.23590192
11electron transport chain (GO:0022900)4.23266366
12neuron cell-cell adhesion (GO:0007158)4.16565047
13ribosomal large subunit biogenesis (GO:0042273)3.92549440
14cullin deneddylation (GO:0010388)3.90096360
15DNA double-strand break processing (GO:0000729)3.86277586
16protein complex biogenesis (GO:0070271)3.77247039
17mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.71703309
18mitochondrial respiratory chain complex I assembly (GO:0032981)3.71703309
19NADH dehydrogenase complex assembly (GO:0010257)3.71703309
20establishment of integrated proviral latency (GO:0075713)3.67661285
21protein deneddylation (GO:0000338)3.67421258
22proteasome assembly (GO:0043248)3.61815588
23oxidative phosphorylation (GO:0006119)3.61270652
24establishment of protein localization to endoplasmic reticulum (GO:0072599)3.59836472
25DNA replication checkpoint (GO:0000076)3.58087985
26GTP biosynthetic process (GO:0006183)3.55420632
27histone exchange (GO:0043486)3.54571192
28ribosomal small subunit biogenesis (GO:0042274)3.52023998
29organelle disassembly (GO:1903008)3.50810400
30positive regulation of cellular response to oxidative stress (GO:1900409)3.47407275
31positive regulation of response to oxidative stress (GO:1902884)3.47407275
32histone mRNA metabolic process (GO:0008334)3.46168070
33translation (GO:0006412)3.42353118
34spliceosomal snRNP assembly (GO:0000387)3.42334730
35dopamine transport (GO:0015872)3.40413326
36positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.39625196
37mitochondrial respiratory chain complex assembly (GO:0033108)3.38011656
38DNA replication-independent nucleosome organization (GO:0034724)3.37554363
39DNA replication-independent nucleosome assembly (GO:0006336)3.37554363
40DNA ligation (GO:0006266)3.36497371
41RNA capping (GO:0036260)3.32526473
427-methylguanosine RNA capping (GO:0009452)3.32526473
437-methylguanosine mRNA capping (GO:0006370)3.31948009
44telomere maintenance via semi-conservative replication (GO:0032201)3.27328760
45ribonucleoprotein complex disassembly (GO:0032988)3.24427631
46establishment of viral latency (GO:0019043)3.24171082
47translational initiation (GO:0006413)3.24071168
48DNA strand elongation involved in DNA replication (GO:0006271)3.23271848
49presynaptic membrane assembly (GO:0097105)3.21745442
50positive regulation of ligase activity (GO:0051351)3.21443080
51protein localization to cilium (GO:0061512)3.15748679
52translational elongation (GO:0006414)3.14947062
53RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.12324730
54tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.12324730
55protein localization to synapse (GO:0035418)3.11285343
56regulation of ubiquitin-protein transferase activity (GO:0051438)3.09553861
57termination of RNA polymerase III transcription (GO:0006386)3.08741784
58transcription elongation from RNA polymerase III promoter (GO:0006385)3.08741784
59nucleotide-excision repair, DNA gap filling (GO:0006297)3.08025856
60purine nucleobase biosynthetic process (GO:0009113)3.07818635
61DNA strand elongation (GO:0022616)3.07601630
62vocalization behavior (GO:0071625)3.05408191
63DNA catabolic process, exonucleolytic (GO:0000738)3.04189264
64negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.03038959
65spliceosomal complex assembly (GO:0000245)3.02698353
66UTP biosynthetic process (GO:0006228)2.99067381
67regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.96594516
68regulation of mitotic spindle checkpoint (GO:1903504)2.96594516
69protein localization to kinetochore (GO:0034501)2.96501103
70regulation of ligase activity (GO:0051340)2.95495768
71hydrogen ion transmembrane transport (GO:1902600)2.95144436
72nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.94345078
73regulation of glutamate secretion (GO:0014048)2.93870511
74maturation of SSU-rRNA (GO:0030490)2.93685816
75regulation of cellular amino acid metabolic process (GO:0006521)2.93366811
76ATP hydrolysis coupled proton transport (GO:0015991)2.92765705
77energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.92765705
78gamma-aminobutyric acid signaling pathway (GO:0007214)2.92573857
79kinetochore organization (GO:0051383)2.91840011
80presynaptic membrane organization (GO:0097090)2.90093071
81regulation of helicase activity (GO:0051095)2.89728845
82rRNA modification (GO:0000154)2.89284169
83synaptic vesicle exocytosis (GO:0016079)2.89086310
84protein K11-linked ubiquitination (GO:0070979)2.87149035
85regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.86083702
86cellular protein complex disassembly (GO:0043624)2.86055139
87telomere maintenance via recombination (GO:0000722)2.85533716
88protein-cofactor linkage (GO:0018065)2.85169730
89ribosome assembly (GO:0042255)2.85102904
90formation of translation preinitiation complex (GO:0001731)2.84511726
91termination of RNA polymerase II transcription (GO:0006369)2.84472711
92guanosine-containing compound biosynthetic process (GO:1901070)2.83438802
93positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.81877762
94establishment of protein localization to mitochondrion (GO:0072655)2.81710573
95viral transcription (GO:0019083)2.80260684
96translational termination (GO:0006415)2.78631612
97inner mitochondrial membrane organization (GO:0007007)2.78501120
98purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.75556567
99regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.74108905
100protein targeting to mitochondrion (GO:0006626)2.73984575
101DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.73327549
102positive regulation of synapse assembly (GO:0051965)2.72912175
103negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.72371329
104negative regulation of ligase activity (GO:0051352)2.72371329
105regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.71299408
106ribosomal small subunit assembly (GO:0000028)2.71226732
107nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.71195664
108cotranslational protein targeting to membrane (GO:0006613)2.70750888
109glutamate receptor signaling pathway (GO:0007215)2.69752757
110protein localization to mitochondrion (GO:0070585)2.69568462
111regulation of protein kinase A signaling (GO:0010738)2.67889716
112signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.67662872
113intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.67662872
114purine nucleoside triphosphate biosynthetic process (GO:0009145)2.65558584
115regulation of mitochondrial translation (GO:0070129)2.65531145
116anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.65463558
117response to histamine (GO:0034776)2.65071449
118signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.63696080
119signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.63696080
120signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.63696080
121startle response (GO:0001964)2.62757302
122proton transport (GO:0015992)2.62625509
123regulation of catecholamine metabolic process (GO:0042069)2.62255879
124regulation of dopamine metabolic process (GO:0042053)2.62255879
125transferrin transport (GO:0033572)2.61581363
126SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.61515592
127ionotropic glutamate receptor signaling pathway (GO:0035235)2.61515107
128transcription elongation from RNA polymerase I promoter (GO:0006362)2.61362295
129protein targeting to ER (GO:0045047)2.60525220
130antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.59688647
131synaptic transmission, dopaminergic (GO:0001963)2.59633270
132postsynaptic membrane organization (GO:0001941)2.59344972
133exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.59082311
134DNA damage response, detection of DNA damage (GO:0042769)2.58773485
135signal transduction involved in DNA damage checkpoint (GO:0072422)2.55767092
136signal transduction involved in DNA integrity checkpoint (GO:0072401)2.55767092
137hydrogen transport (GO:0006818)2.55102884
138protein localization to endoplasmic reticulum (GO:0070972)2.53646457
139positive regulation of protein homodimerization activity (GO:0090073)2.53255095
140signal transduction involved in cell cycle checkpoint (GO:0072395)2.52780108
141ATP biosynthetic process (GO:0006754)2.52738262
142respiratory chain complex IV assembly (GO:0008535)2.52577863
143keratinocyte development (GO:0003334)2.52470127
144neuron-neuron synaptic transmission (GO:0007270)2.51129331

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.17700686
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.44649318
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.31240324
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.17828156
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.02102837
6TAF15_26573619_Chip-Seq_HEK293_Human2.75777226
7SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.63151971
8GBX2_23144817_ChIP-Seq_PC3_Human2.60742344
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.51392320
10FUS_26573619_Chip-Seq_HEK293_Human2.47339596
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.38990829
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.36835988
13TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.28551876
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.26497694
15VDR_22108803_ChIP-Seq_LS180_Human2.24752700
16ZFP57_27257070_Chip-Seq_ESCs_Mouse2.24119309
17MYC_18555785_ChIP-Seq_MESCs_Mouse2.21137716
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.15456383
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.13206509
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.12542220
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.04649447
22POU3F2_20337985_ChIP-ChIP_501MEL_Human2.02700456
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.02156563
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.99723450
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.99593928
26BMI1_23680149_ChIP-Seq_NPCS_Mouse1.95451709
27* ELK1_19687146_ChIP-ChIP_HELA_Human1.88001780
28* VDR_23849224_ChIP-Seq_CD4+_Human1.85669750
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.82358811
30E2F4_17652178_ChIP-ChIP_JURKAT_Human1.79688606
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.79083957
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.79053966
33EWS_26573619_Chip-Seq_HEK293_Human1.74039770
34HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.71571485
35P300_19829295_ChIP-Seq_ESCs_Human1.69265316
36FLI1_27457419_Chip-Seq_LIVER_Mouse1.67903997
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.62833187
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.62279015
39* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.61126511
40E2F1_21310950_ChIP-Seq_MCF-7_Human1.56863713
41RNF2_27304074_Chip-Seq_NSC_Mouse1.55103899
42PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.48852049
43JARID2_20064375_ChIP-Seq_MESCs_Mouse1.48480377
44FOXM1_23109430_ChIP-Seq_U2OS_Human1.48399962
45FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.47681294
46TTF2_22483619_ChIP-Seq_HELA_Human1.45770203
47PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44426249
48DCP1A_22483619_ChIP-Seq_HELA_Human1.43661983
49* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.39737439
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.39389921
51MYC_18940864_ChIP-ChIP_HL60_Human1.37920033
52IGF1R_20145208_ChIP-Seq_DFB_Human1.36254060
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36207277
54MYC_18358816_ChIP-ChIP_MESCs_Mouse1.36057234
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.35007785
56REST_21632747_ChIP-Seq_MESCs_Mouse1.34616493
57MYCN_18555785_ChIP-Seq_MESCs_Mouse1.34390127
58E2F7_22180533_ChIP-Seq_HELA_Human1.34331120
59YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.33205400
60MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.33154459
61FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33047998
62MYC_19079543_ChIP-ChIP_MESCs_Mouse1.32714190
63* FOXP3_21729870_ChIP-Seq_TREG_Human1.31270634
64YY1_21170310_ChIP-Seq_MESCs_Mouse1.29622875
65ER_23166858_ChIP-Seq_MCF-7_Human1.29538969
66SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.29096422
67AR_21909140_ChIP-Seq_LNCAP_Human1.26868472
68PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26849269
69IRF1_19129219_ChIP-ChIP_H3396_Human1.25772303
70EZH2_27304074_Chip-Seq_ESCs_Mouse1.21325527
71TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20872247
72ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.20854972
73XRN2_22483619_ChIP-Seq_HELA_Human1.18870474
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18111505
75* JUN_21703547_ChIP-Seq_K562_Human1.17749739
76SRF_21415370_ChIP-Seq_HL-1_Mouse1.16724028
77PADI4_21655091_ChIP-ChIP_MCF-7_Human1.16496527
78SALL1_21062744_ChIP-ChIP_HESCs_Human1.16194927
79NANOG_16153702_ChIP-ChIP_HESCs_Human1.14162694
80SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.13848948
81ELF1_17652178_ChIP-ChIP_JURKAT_Human1.13599786
82CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.12151549
83SMAD4_21799915_ChIP-Seq_A2780_Human1.10716527
84UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09161498
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08420842
86EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.07561279
87RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.07509104
88POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06926010
89GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06701455
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.06695426
91SOX2_16153702_ChIP-ChIP_HESCs_Human1.06559175
92HOXB4_20404135_ChIP-ChIP_EML_Mouse1.05626372
93* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.04360885
94REST_19997604_ChIP-ChIP_NEURONS_Mouse1.03809125
95* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.03075859
96GABP_19822575_ChIP-Seq_HepG2_Human1.02889627
97ZNF274_21170338_ChIP-Seq_K562_Hela1.02628434
98SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.02351595
99REST_18959480_ChIP-ChIP_MESCs_Mouse1.02183434
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00520635
101* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.00469964
102IKZF1_21737484_ChIP-ChIP_HCT116_Human0.99778012
103FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.99205503
104CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.99186831
105ELK1_22589737_ChIP-Seq_MCF10A_Human0.97820407
106HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.96513725
107TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96437862
108SMAD3_21741376_ChIP-Seq_EPCs_Human0.96410522
109NOTCH1_21737748_ChIP-Seq_TLL_Human0.94427978
110POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.94174193
111P53_22387025_ChIP-Seq_ESCs_Mouse0.92672017
112E2F1_18555785_Chip-Seq_ESCs_Mouse0.92100040
113CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91929223
114EED_16625203_ChIP-ChIP_MESCs_Mouse0.91037525
115* MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.91021887
116SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.90816344
117KDM5A_27292631_Chip-Seq_BREAST_Human0.88972841
118SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.88837321
119E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.88807780
120SALL4_22934838_ChIP-ChIP_CD34+_Human0.86191724
121SOX2_18555785_ChIP-Seq_MESCs_Mouse0.84611951
122TP53_22573176_ChIP-Seq_HFKS_Human0.83866047
123SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.81733133
124SUZ12_27294783_Chip-Seq_NPCs_Mouse0.81510485
125ERG_20887958_ChIP-Seq_HPC-7_Mouse0.80761272
126PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.80400099
127EZH2_27294783_Chip-Seq_NPCs_Mouse0.79291731
128NFE2_27457419_Chip-Seq_LIVER_Mouse0.78937095
129BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.78613517
130CIITA_25753668_ChIP-Seq_RAJI_Human0.78027868
131SOX17_20123909_ChIP-Seq_XEN_Mouse0.72896242

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.78806832
2MP0001529_abnormal_vocalization3.19742660
3MP0008877_abnormal_DNA_methylation3.00333106
4MP0001968_abnormal_touch/_nociception2.76947586
5MP0004859_abnormal_synaptic_plasticity2.74430206
6MP0006276_abnormal_autonomic_nervous2.73413109
7MP0003635_abnormal_synaptic_transmissio2.71071552
8MP0009745_abnormal_behavioral_response2.63018059
9MP0002736_abnormal_nociception_after2.62103846
10MP0001188_hyperpigmentation2.55374517
11MP0003111_abnormal_nucleus_morphology2.48462791
12MP0009379_abnormal_foot_pigmentation2.42375861
13MP0002063_abnormal_learning/memory/cond2.33442226
14MP0001905_abnormal_dopamine_level2.29538840
15MP0003806_abnormal_nucleotide_metabolis2.26068716
16MP0002572_abnormal_emotion/affect_behav2.23675205
17MP0002064_seizures2.21032865
18MP0009697_abnormal_copulation2.19668260
19MP0006292_abnormal_olfactory_placode2.15310692
20MP0004270_analgesia2.12570207
21MP0003123_paternal_imprinting2.11651085
22MP0002735_abnormal_chemical_nociception2.01741525
23MP0002272_abnormal_nervous_system2.00250620
24MP0003787_abnormal_imprinting1.99377257
25MP0008007_abnormal_cellular_replicative1.98359964
26MP0002163_abnormal_gland_morphology1.97485656
27MP0001501_abnormal_sleep_pattern1.97455327
28MP0009046_muscle_twitch1.95985071
29MP0006036_abnormal_mitochondrial_physio1.94550978
30MP0003122_maternal_imprinting1.89750085
31MP0002734_abnormal_mechanical_nocicepti1.84628626
32MP0001984_abnormal_olfaction1.83911590
33MP0001440_abnormal_grooming_behavior1.82636330
34MP0005423_abnormal_somatic_nervous1.76497781
35MP0003121_genomic_imprinting1.72803231
36MP0003890_abnormal_embryonic-extraembry1.70583694
37MP0008057_abnormal_DNA_replication1.69356933
38MP0003186_abnormal_redox_activity1.69076792
39MP0002184_abnormal_innervation1.60293611
40MP0002067_abnormal_sensory_capabilities1.57422963
41MP0001486_abnormal_startle_reflex1.53166664
42MP0005379_endocrine/exocrine_gland_phen1.52211008
43MP0002837_dystrophic_cardiac_calcinosis1.49478777
44MP0000778_abnormal_nervous_system1.48455710
45MP0005386_behavior/neurological_phenoty1.48265371
46MP0004924_abnormal_behavior1.48265371
47MP0003567_abnormal_fetal_cardiomyocyte1.48022388
48MP0001970_abnormal_pain_threshold1.45886678
49MP0002822_catalepsy1.44948010
50MP0002102_abnormal_ear_morphology1.42724474
51MP0002733_abnormal_thermal_nociception1.41247569
52MP0005409_darkened_coat_color1.40889446
53MP0005253_abnormal_eye_physiology1.37089366
54MP0002638_abnormal_pupillary_reflex1.35866617
55MP0004147_increased_porphyrin_level1.35546783
56MP0002557_abnormal_social/conspecific_i1.32280093
57MP0004957_abnormal_blastocyst_morpholog1.32176202
58MP0003221_abnormal_cardiomyocyte_apopto1.31527448
59MP0003941_abnormal_skin_development1.30812841
60MP0003136_yellow_coat_color1.29011296
61MP0001293_anophthalmia1.28574152
62MP0008058_abnormal_DNA_repair1.26046159
63MP0002876_abnormal_thyroid_physiology1.25627095
64MP0004142_abnormal_muscle_tone1.24431420
65MP0010094_abnormal_chromosome_stability1.20697352
66MP0005646_abnormal_pituitary_gland1.18953529
67MP0005084_abnormal_gallbladder_morpholo1.15454326
68MP0005645_abnormal_hypothalamus_physiol1.13975480
69MP0008995_early_reproductive_senescence1.11482999
70MP0010386_abnormal_urinary_bladder1.08704273
71MP0008932_abnormal_embryonic_tissue1.06686072
72MP0003693_abnormal_embryo_hatching1.06614907
73MP0005499_abnormal_olfactory_system1.05934516
74MP0005394_taste/olfaction_phenotype1.05934516
75MP0002090_abnormal_vision1.05207084
76MP0003315_abnormal_perineum_morphology1.03404969
77MP0000358_abnormal_cell_content/1.03304677
78MP0000350_abnormal_cell_proliferation1.03267140
79MP0000631_abnormal_neuroendocrine_gland1.01801533
80MP0003786_premature_aging1.00975266
81MP0001986_abnormal_taste_sensitivity1.00452893
82MP0006072_abnormal_retinal_apoptosis1.00072364
83MP0005171_absent_coat_pigmentation0.99113752
84MP0001286_abnormal_eye_development0.98540083
85MP0003718_maternal_effect0.98270497
86MP0008789_abnormal_olfactory_epithelium0.98220753
87MP0003937_abnormal_limbs/digits/tail_de0.97188478
88MP0004742_abnormal_vestibular_system0.92194375
89MP0002066_abnormal_motor_capabilities/c0.90755013
90MP0001697_abnormal_embryo_size0.90351318
91MP0002210_abnormal_sex_determination0.90314951
92MP0002160_abnormal_reproductive_system0.89768054
93MP0004215_abnormal_myocardial_fiber0.89305977
94MP0002882_abnormal_neuron_morphology0.89088593
95MP0000049_abnormal_middle_ear0.87412693
96MP0005671_abnormal_response_to0.87203072
97MP0000569_abnormal_digit_pigmentation0.86994692
98MP0001963_abnormal_hearing_physiology0.85890346
99MP0002751_abnormal_autonomic_nervous0.85840013
100MP0002233_abnormal_nose_morphology0.85090191
101MP0005187_abnormal_penis_morphology0.84370880
102MP0002095_abnormal_skin_pigmentation0.84361975
103MP0004811_abnormal_neuron_physiology0.84023407
104MP0001502_abnormal_circadian_rhythm0.83978695
105MP0001919_abnormal_reproductive_system0.83023914
106MP0001485_abnormal_pinna_reflex0.82589638
107MP0006035_abnormal_mitochondrial_morpho0.82563793
108MP0002234_abnormal_pharynx_morphology0.80830089
109MP0000015_abnormal_ear_pigmentation0.80582911
110MP0000372_irregular_coat_pigmentation0.79498957
111MP0003698_abnormal_male_reproductive0.78814875
112MP0001929_abnormal_gametogenesis0.78358000
113MP0003879_abnormal_hair_cell0.78133484
114MP0001730_embryonic_growth_arrest0.78020666
115MP0000955_abnormal_spinal_cord0.77991607
116MP0000516_abnormal_urinary_system0.76107499
117MP0005367_renal/urinary_system_phenotyp0.76107499
118MP0002152_abnormal_brain_morphology0.75085632
119MP0000026_abnormal_inner_ear0.74495818
120MP0000313_abnormal_cell_death0.74338136
121MP0002752_abnormal_somatic_nervous0.73587030
122MP0003077_abnormal_cell_cycle0.73512254
123MP0005391_vision/eye_phenotype0.73152736
124MP0001764_abnormal_homeostasis0.72860740
125MP0005408_hypopigmentation0.71478952
126MP0001177_atelectasis0.70830917
127MP0001727_abnormal_embryo_implantation0.69643482
128MP0002084_abnormal_developmental_patter0.69640097
129MP0010307_abnormal_tumor_latency0.69023929
130MP0000647_abnormal_sebaceous_gland0.68777603
131MP0002277_abnormal_respiratory_mucosa0.68680062
132MP0005551_abnormal_eye_electrophysiolog0.68418904
133MP0005389_reproductive_system_phenotype0.68373773
134MP0001145_abnormal_male_reproductive0.68310833
135MP0000653_abnormal_sex_gland0.68110609
136MP0008872_abnormal_physiological_respon0.67145218
137MP0002938_white_spotting0.66403538
138MP0003938_abnormal_ear_development0.62185865
139MP0001664_abnormal_digestion0.59388061
140MP0005174_abnormal_tail_pigmentation0.57634926

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.68465939
2Abnormal mitochondria in muscle tissue (HP:0008316)5.04461529
3Progressive macrocephaly (HP:0004481)4.87803302
4Mitochondrial inheritance (HP:0001427)4.82412463
5Focal motor seizures (HP:0011153)4.33984199
6Acute encephalopathy (HP:0006846)4.17460917
7Increased hepatocellular lipid droplets (HP:0006565)4.12232163
8Increased CSF lactate (HP:0002490)4.03365359
9Hepatocellular necrosis (HP:0001404)3.51337869
10Atonic seizures (HP:0010819)3.30840074
11Lipid accumulation in hepatocytes (HP:0006561)3.29505228
12Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.26299941
13Hyperventilation (HP:0002883)3.22400301
14Renal Fanconi syndrome (HP:0001994)3.21759921
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.15600368
16Optic disc pallor (HP:0000543)3.12565835
17Medial flaring of the eyebrow (HP:0010747)3.02376813
18Epileptic encephalopathy (HP:0200134)2.97106301
19Congenital, generalized hypertrichosis (HP:0004540)2.90417163
20Abnormal hair whorl (HP:0010721)2.88476017
21Gait imbalance (HP:0002141)2.88178565
223-Methylglutaconic aciduria (HP:0003535)2.87165275
23Colon cancer (HP:0003003)2.83415840
24Exercise intolerance (HP:0003546)2.82494501
25Aplastic anemia (HP:0001915)2.81154388
26Congenital primary aphakia (HP:0007707)2.77735542
27Exertional dyspnea (HP:0002875)2.76823761
28Absence seizures (HP:0002121)2.70354757
29Broad-based gait (HP:0002136)2.66495471
30Respiratory difficulties (HP:0002880)2.62661031
31Febrile seizures (HP:0002373)2.61066997
32Nephrogenic diabetes insipidus (HP:0009806)2.58798486
33Leukodystrophy (HP:0002415)2.57026446
34Increased serum pyruvate (HP:0003542)2.55142683
35Abnormality of glycolysis (HP:0004366)2.55142683
36Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.53813469
37Abnormality of alanine metabolism (HP:0010916)2.53813469
38Hyperalaninemia (HP:0003348)2.53813469
39Meckel diverticulum (HP:0002245)2.51447643
40Increased intramyocellular lipid droplets (HP:0012240)2.51166066
41Decreased activity of mitochondrial respiratory chain (HP:0008972)2.51096948
42Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.51096948
43Respiratory failure (HP:0002878)2.44886713
44Dialeptic seizures (HP:0011146)2.44150591
45Hepatic necrosis (HP:0002605)2.44060818
46Abnormality of methionine metabolism (HP:0010901)2.43586532
47Abnormality of chromosome stability (HP:0003220)2.43280269
48Abnormality of the ileum (HP:0001549)2.41835943
49Methylmalonic acidemia (HP:0002912)2.41480941
50Birth length less than 3rd percentile (HP:0003561)2.40289566
51Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.37606122
52Increased serum lactate (HP:0002151)2.37376977
53Lactic acidosis (HP:0003128)2.37344200
54Focal seizures (HP:0007359)2.35457068
55Aplasia/Hypoplasia of the uvula (HP:0010293)2.33305578
56Delusions (HP:0000746)2.32937412
57Abnormality of serum amino acid levels (HP:0003112)2.32675293
58Cerebral edema (HP:0002181)2.30281114
59Myokymia (HP:0002411)2.29876238
60Visual hallucinations (HP:0002367)2.29063291
61Abnormality of the labia minora (HP:0012880)2.26241356
62Type I transferrin isoform profile (HP:0003642)2.25385066
63Hypothermia (HP:0002045)2.25272512
64Abnormality of cells of the erythroid lineage (HP:0012130)2.24783304
65Abnormal respiratory epithelium morphology (HP:0012253)2.24472540
66Abnormal respiratory motile cilium morphology (HP:0005938)2.24472540
67Amblyopia (HP:0000646)2.22816325
68Abnormal ciliary motility (HP:0012262)2.19907978
69Genital tract atresia (HP:0001827)2.17206912
70Lethargy (HP:0001254)2.15948211
71Protruding tongue (HP:0010808)2.15573341
72Methylmalonic aciduria (HP:0012120)2.13568001
73Vaginal atresia (HP:0000148)2.12673552
74Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.11499312
75Abnormal protein N-linked glycosylation (HP:0012347)2.11499312
76Abnormal protein glycosylation (HP:0012346)2.11499312
77Abnormal glycosylation (HP:0012345)2.11499312
78Degeneration of anterior horn cells (HP:0002398)2.11132187
79Abnormality of the anterior horn cell (HP:0006802)2.11132187
80X-linked dominant inheritance (HP:0001423)2.09497273
81Hyperglycinemia (HP:0002154)2.05586146
82Poor coordination (HP:0002370)2.05202873
83CNS demyelination (HP:0007305)2.03076573
84Chromosomal breakage induced by crosslinking agents (HP:0003221)2.02983184
85Abnormality of renal resorption (HP:0011038)2.02855048
86Chromsome breakage (HP:0040012)1.98995818
87Medulloblastoma (HP:0002885)1.98671812
88Abnormal number of erythroid precursors (HP:0012131)1.98452381
89Abnormal lung lobation (HP:0002101)1.98087463
90Megaloblastic anemia (HP:0001889)1.97445049
91Dynein arm defect of respiratory motile cilia (HP:0012255)1.96967856
92Absent/shortened dynein arms (HP:0200106)1.96967856
93Abnormality of the preputium (HP:0100587)1.96856770
94Abnormality of aspartate family amino acid metabolism (HP:0010899)1.96596156
95Renal cortical cysts (HP:0000803)1.96206629
96Inability to walk (HP:0002540)1.95656196
97Limb dystonia (HP:0002451)1.90802200
98Progressive inability to walk (HP:0002505)1.89320100
99Reticulocytopenia (HP:0001896)1.89206079
100Aplasia/Hypoplasia of the tibia (HP:0005772)1.88741834
101Abnormal respiratory motile cilium physiology (HP:0012261)1.88555401
102Reduced antithrombin III activity (HP:0001976)1.88051373
103Cerebral hypomyelination (HP:0006808)1.87658772
104Pancreatic fibrosis (HP:0100732)1.87226718
105Pheochromocytoma (HP:0002666)1.86206475
106Macrocytic anemia (HP:0001972)1.84146015
107Stenosis of the external auditory canal (HP:0000402)1.82293670
108Breast hypoplasia (HP:0003187)1.81175175
109Oral leukoplakia (HP:0002745)1.80852174
110Volvulus (HP:0002580)1.80229531
111Triphalangeal thumb (HP:0001199)1.78797912
112Short tibia (HP:0005736)1.78753912
113Septo-optic dysplasia (HP:0100842)1.78647484
114Supernumerary spleens (HP:0009799)1.78044327
115Esotropia (HP:0000565)1.77997557
116Neuroendocrine neoplasm (HP:0100634)1.76712518
117Increased IgM level (HP:0003496)1.76348500
118Neoplasm of the adrenal gland (HP:0100631)1.76186136
119Unsteady gait (HP:0002317)1.76001564
120Parakeratosis (HP:0001036)1.75946033
121Fair hair (HP:0002286)1.75128764
122Progressive cerebellar ataxia (HP:0002073)1.74405694
123Abnormality of placental membranes (HP:0011409)1.74045128
124Amniotic constriction ring (HP:0009775)1.74045128
125Pancytopenia (HP:0001876)1.73546268
126Hydroureter (HP:0000072)1.73484468
127Small intestinal stenosis (HP:0012848)1.73346448
128Duodenal stenosis (HP:0100867)1.73346448
129Cortical dysplasia (HP:0002539)1.71668779
130Emotional lability (HP:0000712)1.70823686
131Multiple enchondromatosis (HP:0005701)1.70730755
132Neoplasm of the colon (HP:0100273)1.70070416
133Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.70048698
134Generalized tonic-clonic seizures (HP:0002069)1.69539682
135Postnatal microcephaly (HP:0005484)1.68460551
136Abnormality of the pons (HP:0007361)1.68307553
137Increased muscle lipid content (HP:0009058)1.66978650
138Anxiety (HP:0000739)1.66827893
139Oligodactyly (hands) (HP:0001180)1.64165073
140Drooling (HP:0002307)1.63659417
141Excessive salivation (HP:0003781)1.63659417
142Poor suck (HP:0002033)1.63595027
143Pancreatic cysts (HP:0001737)1.61481411
144Heterochromia iridis (HP:0001100)1.60535771
145Molar tooth sign on MRI (HP:0002419)1.60431694
146Abnormality of midbrain morphology (HP:0002418)1.60431694
147Rhinitis (HP:0012384)1.59578418
148Pallor (HP:0000980)1.59431492
149Microvesicular hepatic steatosis (HP:0001414)1.56884542
150True hermaphroditism (HP:0010459)1.56563437
151Polyphagia (HP:0002591)1.54530927
152Aplasia/Hypoplasia of the lens (HP:0008063)1.54262593

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K124.25677308
2CASK4.01177684
3PNCK3.06014238
4STK162.93124420
5MAP2K72.75007267
6VRK22.66351034
7RIPK42.63237853
8NEK12.54955505
9ZAK2.52717877
10NTRK32.46033522
11EPHA42.39863505
12NME12.39595172
13PLK22.33266125
14MAP3K42.23445466
15BMPR22.09428208
16ARAF2.01684113
17TRIM281.91321581
18TTK1.88842078
19ERBB31.85109568
20WEE11.75104964
21EIF2AK11.74737546
22BUB11.72657517
23MAP4K21.64739885
24DAPK11.63851125
25VRK11.62360818
26SRPK11.57672192
27CDK191.53235572
28GRK51.50573283
29MST41.47818846
30BCR1.46893820
31TSSK61.44131726
32SCYL21.43459104
33CDC71.42324264
34NUAK11.39628661
35MINK11.37695551
36SIK31.36741155
37TNIK1.32031285
38MARK11.29863964
39EIF2AK31.29560508
40GRK71.29029429
41CCNB11.24916011
42MAP3K91.21031017
43MAPK131.20442139
44PLK31.14600031
45CSNK1A1L1.14376042
46PBK1.13495348
47MAP2K41.12481747
48ACVR1B1.10355810
49CDK81.07049256
50MUSK1.05814373
51ADRBK21.03698917
52BRAF1.03332139
53PLK41.03177234
54FES1.03092498
55MKNK21.01789570
56BMPR1B1.00125208
57TXK0.99803196
58GRK60.99242023
59STK38L0.99237455
60TAF10.98380646
61KSR10.97264623
62MKNK10.95034069
63FGR0.94681636
64AURKB0.94401793
65TLK10.91015704
66EIF2AK20.90459323
67ATR0.88011661
68DYRK30.86605195
69BCKDK0.84557660
70CAMK2A0.84294717
71CAMK2B0.84161195
72MYLK0.83531759
73PASK0.82933910
74RPS6KA40.80095395
75DYRK20.78539606
76PDK20.77434566
77RAF10.76985131
78PTK2B0.73129536
79DYRK1A0.67903280
80PRKCG0.67499237
81OXSR10.66752562
82RPS6KA50.64757202
83NTRK20.64689921
84CSNK1G30.64012336
85AKT30.63144989
86BRSK20.59953175
87INSRR0.58686346
88ADRBK10.58172032
89CDK140.56811325
90ATM0.55805405
91FRK0.55387396
92NME20.55174996
93CDK30.54330294
94CDK50.54199629
95CSNK1G20.53710619
96PLK10.53210948
97CDK180.51101437
98MAP3K60.50478088
99SYK0.50098486
100DAPK20.49579856
101AURKA0.49061534
102MAP3K130.47370163
103CLK10.45063513
104CSNK2A20.44901285
105CAMKK20.44039456
106SIK20.43881040
107ALK0.42140170
108YES10.41765966
109PRKCE0.41560980
110ERBB40.41340081
111CDK150.41095831
112CHEK10.40471844
113BRSK10.40451167
114CSNK1E0.40373562
115* CSNK2A10.40343065
116KDR0.39888345
117WNK30.39302731
118CDK11A0.38019247
119MAP3K50.37664391
120UHMK10.36798132
121ABL20.36713059
122CAMK2D0.35701064
123NEK20.35409723
124TEC0.33929388
125PINK10.33781332
126LIMK10.32681644
127CDK10.32028140
128CHEK20.31951603
129GRK10.31293684
130FGFR10.30033420
131ROCK20.29008449
132CSNK1A10.28682553
133PIM20.28519605
134PRKACA0.28435995
135CDK70.28036807
136PRKACB0.27994438
137MOS0.27613399
138CSNK1G10.26813124
139TNK20.26299158
140STK240.24207923
141MAPKAPK50.23579437

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.33445836
2Parkinsons disease_Homo sapiens_hsa050123.61669303
3Proteasome_Homo sapiens_hsa030503.52786289
4Ribosome_Homo sapiens_hsa030103.04879994
5Alzheimers disease_Homo sapiens_hsa050102.94432874
6Nicotine addiction_Homo sapiens_hsa050332.93213282
7Huntingtons disease_Homo sapiens_hsa050162.82569782
8RNA polymerase_Homo sapiens_hsa030202.59645956
9Collecting duct acid secretion_Homo sapiens_hsa049662.41222382
10Protein export_Homo sapiens_hsa030602.19115014
11Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.91889239
12Synaptic vesicle cycle_Homo sapiens_hsa047211.85726870
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.85059053
14Long-term potentiation_Homo sapiens_hsa047201.76090170
15Spliceosome_Homo sapiens_hsa030401.74171155
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.73358903
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.71189400
18Amphetamine addiction_Homo sapiens_hsa050311.63698366
19Basal transcription factors_Homo sapiens_hsa030221.59745948
20Cardiac muscle contraction_Homo sapiens_hsa042601.59534825
21One carbon pool by folate_Homo sapiens_hsa006701.56881365
22Propanoate metabolism_Homo sapiens_hsa006401.54886264
23Vibrio cholerae infection_Homo sapiens_hsa051101.53680698
24Mismatch repair_Homo sapiens_hsa034301.47059245
25Serotonergic synapse_Homo sapiens_hsa047261.45906411
26Morphine addiction_Homo sapiens_hsa050321.40665697
27Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.39887720
28Nucleotide excision repair_Homo sapiens_hsa034201.39043063
29Olfactory transduction_Homo sapiens_hsa047401.39017530
30GABAergic synapse_Homo sapiens_hsa047271.38272922
31Homologous recombination_Homo sapiens_hsa034401.37289035
32Taste transduction_Homo sapiens_hsa047421.36955952
33Circadian entrainment_Homo sapiens_hsa047131.36824082
34Dopaminergic synapse_Homo sapiens_hsa047281.34740030
35Glutamatergic synapse_Homo sapiens_hsa047241.31754278
36DNA replication_Homo sapiens_hsa030301.31104725
37Phototransduction_Homo sapiens_hsa047441.30580425
38RNA degradation_Homo sapiens_hsa030181.27519263
39Pyrimidine metabolism_Homo sapiens_hsa002401.22417371
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.22052008
41RNA transport_Homo sapiens_hsa030131.19661980
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15834327
43Oocyte meiosis_Homo sapiens_hsa041141.15770824
44Type I diabetes mellitus_Homo sapiens_hsa049401.12183340
45Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.09104291
46Pyruvate metabolism_Homo sapiens_hsa006201.09103473
47Long-term depression_Homo sapiens_hsa047301.08257761
48Folate biosynthesis_Homo sapiens_hsa007901.04218828
49Fatty acid elongation_Homo sapiens_hsa000621.04151074
50Rheumatoid arthritis_Homo sapiens_hsa053231.00377664
51Cysteine and methionine metabolism_Homo sapiens_hsa002700.99407936
52Non-homologous end-joining_Homo sapiens_hsa034500.98580563
53Allograft rejection_Homo sapiens_hsa053300.95666102
54Renin secretion_Homo sapiens_hsa049240.94415222
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91569613
56Steroid biosynthesis_Homo sapiens_hsa001000.90831874
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.89631530
58Calcium signaling pathway_Homo sapiens_hsa040200.89151490
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.89139360
60Graft-versus-host disease_Homo sapiens_hsa053320.88884529
61Purine metabolism_Homo sapiens_hsa002300.88285964
62Fanconi anemia pathway_Homo sapiens_hsa034600.86621806
63Butanoate metabolism_Homo sapiens_hsa006500.84296249
64Autoimmune thyroid disease_Homo sapiens_hsa053200.83787068
65Salivary secretion_Homo sapiens_hsa049700.83153944
66Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.81379159
672-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.77268705
68Cocaine addiction_Homo sapiens_hsa050300.72810525
69Cell cycle_Homo sapiens_hsa041100.72067818
70Cholinergic synapse_Homo sapiens_hsa047250.71512010
71Alcoholism_Homo sapiens_hsa050340.71267888
72Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.70483396
73mRNA surveillance pathway_Homo sapiens_hsa030150.69863442
74Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.66640479
75Oxytocin signaling pathway_Homo sapiens_hsa049210.66549814
76Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.64427637
77Peroxisome_Homo sapiens_hsa041460.63907571
78Carbon metabolism_Homo sapiens_hsa012000.63103767
79Epstein-Barr virus infection_Homo sapiens_hsa051690.63061162
80Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.60403305
81Asthma_Homo sapiens_hsa053100.60367270
82Base excision repair_Homo sapiens_hsa034100.59847729
83Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58628537
84Biosynthesis of amino acids_Homo sapiens_hsa012300.57775861
85Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.57432194
86Glutathione metabolism_Homo sapiens_hsa004800.54636502
87African trypanosomiasis_Homo sapiens_hsa051430.53850935
88Gastric acid secretion_Homo sapiens_hsa049710.53732855
89Phagosome_Homo sapiens_hsa041450.51764729
90Selenocompound metabolism_Homo sapiens_hsa004500.51592313
91p53 signaling pathway_Homo sapiens_hsa041150.51569145
92Vitamin B6 metabolism_Homo sapiens_hsa007500.51246265
93Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.50914821
94Insulin secretion_Homo sapiens_hsa049110.48584411
95Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.46850385
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45445542
97GnRH signaling pathway_Homo sapiens_hsa049120.44424161
98Melanogenesis_Homo sapiens_hsa049160.42108056
99Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.41786370
100Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41765895
101Primary immunodeficiency_Homo sapiens_hsa053400.41750011
102Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41642405
103Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.40820939
104Aldosterone synthesis and secretion_Homo sapiens_hsa049250.39629948
105Axon guidance_Homo sapiens_hsa043600.38851655
106N-Glycan biosynthesis_Homo sapiens_hsa005100.37904761
107Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.37332540
108Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.37113041
109Gap junction_Homo sapiens_hsa045400.37082987
110Sulfur metabolism_Homo sapiens_hsa009200.36816956
111Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.36497988
112Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35278856
113Nitrogen metabolism_Homo sapiens_hsa009100.33926636
114Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.32905942
115cAMP signaling pathway_Homo sapiens_hsa040240.32329349
116Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32139805
117Fatty acid metabolism_Homo sapiens_hsa012120.31939328
118Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.29105425
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.29034926
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.28647841
121Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26708399
122Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.26103081
123Antigen processing and presentation_Homo sapiens_hsa046120.25172259
124Estrogen signaling pathway_Homo sapiens_hsa049150.24801766
125cGMP-PKG signaling pathway_Homo sapiens_hsa040220.23987110
126Sulfur relay system_Homo sapiens_hsa041220.23414061
127T cell receptor signaling pathway_Homo sapiens_hsa046600.23331448
128Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.22952220
129Shigellosis_Homo sapiens_hsa051310.22915974
130Circadian rhythm_Homo sapiens_hsa047100.22048971
131Ras signaling pathway_Homo sapiens_hsa040140.20369572
132Wnt signaling pathway_Homo sapiens_hsa043100.19294731
133Intestinal immune network for IgA production_Homo sapiens_hsa046720.18895624
134Ether lipid metabolism_Homo sapiens_hsa005650.18407669
135Systemic lupus erythematosus_Homo sapiens_hsa053220.17515740
136beta-Alanine metabolism_Homo sapiens_hsa004100.17103292
137Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.16367276
138Metabolic pathways_Homo sapiens_hsa011000.16178079
139Regulation of autophagy_Homo sapiens_hsa041400.16022648
140Tryptophan metabolism_Homo sapiens_hsa003800.14877944
141Drug metabolism - other enzymes_Homo sapiens_hsa009830.13078337
142Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.12684081
143Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.12497940

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »