

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | dopamine transport (GO:0015872) | 7.71826309 |
| 2 | substrate-independent telencephalic tangential migration (GO:0021826) | 6.50670079 |
| 3 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 6.50670079 |
| 4 | DNA deamination (GO:0045006) | 5.97139687 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.70235350 |
| 6 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 5.37363201 |
| 7 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 5.37363201 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.37139480 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 5.37139480 |
| 10 | cytidine deamination (GO:0009972) | 4.91243155 |
| 11 | cytidine metabolic process (GO:0046087) | 4.91243155 |
| 12 | cytidine catabolic process (GO:0006216) | 4.91243155 |
| 13 | peristalsis (GO:0030432) | 4.77593314 |
| 14 | mating behavior (GO:0007617) | 4.74952493 |
| 15 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 4.65747624 |
| 16 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.63073226 |
| 17 | chaperone-mediated protein transport (GO:0072321) | 4.50191031 |
| 18 | catecholamine transport (GO:0051937) | 4.45659349 |
| 19 | cell proliferation in forebrain (GO:0021846) | 4.39919774 |
| 20 | monoamine transport (GO:0015844) | 4.39516790 |
| 21 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.39387094 |
| 22 | positive regulation of protein homodimerization activity (GO:0090073) | 4.34655629 |
| 23 | maternal behavior (GO:0042711) | 4.26192740 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.20166747 |
| 25 | regulation of hypersensitivity (GO:0002883) | 4.10954203 |
| 26 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 4.10636360 |
| 27 | platelet dense granule organization (GO:0060155) | 4.03837097 |
| 28 | regulation of dopamine metabolic process (GO:0042053) | 4.02416356 |
| 29 | regulation of catecholamine metabolic process (GO:0042069) | 4.02416356 |
| 30 | lens fiber cell development (GO:0070307) | 3.97397941 |
| 31 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.94842875 |
| 32 | parental behavior (GO:0060746) | 3.93510033 |
| 33 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.91210113 |
| 34 | maturation of 5.8S rRNA (GO:0000460) | 3.91155283 |
| 35 | regulation of neurotransmitter uptake (GO:0051580) | 3.90019754 |
| 36 | transmission of nerve impulse (GO:0019226) | 3.87638758 |
| 37 | electron transport chain (GO:0022900) | 3.80970929 |
| 38 | respiratory electron transport chain (GO:0022904) | 3.78537864 |
| 39 | protein complex biogenesis (GO:0070271) | 3.74552883 |
| 40 | negative regulation of mast cell activation (GO:0033004) | 3.73292161 |
| 41 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 3.52712004 |
| 42 | synaptic transmission, dopaminergic (GO:0001963) | 3.52320895 |
| 43 | prepulse inhibition (GO:0060134) | 3.45966070 |
| 44 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.43977090 |
| 45 | NADH dehydrogenase complex assembly (GO:0010257) | 3.43977090 |
| 46 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.43977090 |
| 47 | adult walking behavior (GO:0007628) | 3.40503531 |
| 48 | dentate gyrus development (GO:0021542) | 3.37606188 |
| 49 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 3.36435725 |
| 50 | ribosomal small subunit assembly (GO:0000028) | 3.30312766 |
| 51 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.23040377 |
| 52 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 3.22652110 |
| 53 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 3.22174174 |
| 54 | cerebellar granule cell differentiation (GO:0021707) | 3.22108542 |
| 55 | behavioral response to cocaine (GO:0048148) | 3.18721289 |
| 56 | striatum development (GO:0021756) | 3.18545255 |
| 57 | phasic smooth muscle contraction (GO:0014821) | 3.18226363 |
| 58 | negative regulation of heart rate (GO:0010459) | 3.17318749 |
| 59 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.12906177 |
| 60 | protein localization to cilium (GO:0061512) | 3.10964738 |
| 61 | positive regulation of synapse assembly (GO:0051965) | 3.09587757 |
| 62 | neuronal action potential (GO:0019228) | 3.09305123 |
| 63 | DNA demethylation (GO:0080111) | 3.09023716 |
| 64 | ribosomal large subunit biogenesis (GO:0042273) | 3.07372617 |
| 65 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.05803891 |
| 66 | positive regulation of mast cell degranulation (GO:0043306) | 3.05803891 |
| 67 | hydrogen ion transmembrane transport (GO:1902600) | 3.04522617 |
| 68 | tryptophan catabolic process (GO:0006569) | 3.04022530 |
| 69 | indole-containing compound catabolic process (GO:0042436) | 3.04022530 |
| 70 | indolalkylamine catabolic process (GO:0046218) | 3.04022530 |
| 71 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.03523211 |
| 72 | GPI anchor biosynthetic process (GO:0006506) | 2.99135621 |
| 73 | ATP biosynthetic process (GO:0006754) | 2.98200962 |
| 74 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.97269261 |
| 75 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.87071761 |
| 76 | protein-cofactor linkage (GO:0018065) | 2.83058217 |
| 77 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.82585695 |
| 78 | proton transport (GO:0015992) | 2.80765743 |
| 79 | respiratory chain complex IV assembly (GO:0008535) | 2.80424288 |
| 80 | neuron fate determination (GO:0048664) | 2.79239753 |
| 81 | GPI anchor metabolic process (GO:0006505) | 2.78677740 |
| 82 | hydrogen transport (GO:0006818) | 2.73237351 |
| 83 | axonemal dynein complex assembly (GO:0070286) | 2.72852123 |
| 84 | positive regulation of mast cell activation (GO:0033005) | 2.70785240 |
| 85 | sequestering of actin monomers (GO:0042989) | 2.68515678 |
| 86 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.65505177 |
| 87 | anterograde synaptic vesicle transport (GO:0048490) | 2.62561502 |
| 88 | neuronal action potential propagation (GO:0019227) | 2.60796537 |
| 89 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.60363143 |
| 90 | grooming behavior (GO:0007625) | 2.58406851 |
| 91 | behavioral response to nicotine (GO:0035095) | 2.57445611 |
| 92 | response to amphetamine (GO:0001975) | 2.57124103 |
| 93 | galactose catabolic process (GO:0019388) | 2.56200752 |
| 94 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.55017928 |
| 95 | auditory receptor cell stereocilium organization (GO:0060088) | 2.48809880 |
| 96 | centriole replication (GO:0007099) | 2.48619783 |
| 97 | somatic stem cell division (GO:0048103) | 2.44900133 |
| 98 | immunoglobulin mediated immune response (GO:0016064) | 2.44259792 |
| 99 | cytochrome complex assembly (GO:0017004) | 2.42322495 |
| 100 | protein polyglutamylation (GO:0018095) | 2.42099545 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.64267244 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 2.90805173 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.89613030 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.89552231 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.87443622 |
| 6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.85393950 |
| 7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.82660742 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.64582527 |
| 9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.54249729 |
| 10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.41471809 |
| 11 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.32020903 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.27443105 |
| 13 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.12702222 |
| 14 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.11982600 |
| 15 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.09682543 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.09633624 |
| 17 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.07302690 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.03730670 |
| 19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.96174770 |
| 20 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.94041906 |
| 21 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.90825595 |
| 22 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.89037548 |
| 23 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.85014250 |
| 24 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.78299299 |
| 25 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.77678047 |
| 26 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.76854274 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.74509391 |
| 28 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.70992082 |
| 29 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.67190573 |
| 30 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.66931799 |
| 31 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.66040412 |
| 32 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.63467810 |
| 33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.63430891 |
| 34 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.62744048 |
| 35 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.59934775 |
| 36 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.58297910 |
| 37 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.58204449 |
| 38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.53435045 |
| 39 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.51926653 |
| 40 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.50710077 |
| 41 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.50710077 |
| 42 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.48852495 |
| 43 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.46067693 |
| 44 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.46067693 |
| 45 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.42062901 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.38667490 |
| 47 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.37512360 |
| 48 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.37417120 |
| 49 | AR_25329375_ChIP-Seq_VCAP_Human | 1.33769397 |
| 50 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.31106391 |
| 51 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.29089106 |
| 52 | GATA3_26560356_Chip-Seq_TH2_Human | 1.27495653 |
| 53 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.23732328 |
| 54 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.23207345 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.23086984 |
| 56 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.22976970 |
| 57 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.22878589 |
| 58 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.21981209 |
| 59 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.21499180 |
| 60 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.19298892 |
| 61 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.18906247 |
| 62 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.18357477 |
| 63 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.17791315 |
| 64 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.15256947 |
| 65 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.12571648 |
| 66 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.10037883 |
| 67 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.09764210 |
| 68 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08768918 |
| 69 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.07366025 |
| 70 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.06901826 |
| 71 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.05969557 |
| 72 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.05077233 |
| 73 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.04019275 |
| 74 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03114323 |
| 75 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.02881626 |
| 76 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.02396714 |
| 77 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.02025256 |
| 78 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.01824808 |
| 79 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.01759960 |
| 80 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.99662744 |
| 81 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.99165013 |
| 82 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.98786178 |
| 83 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.98553796 |
| 84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.97567168 |
| 85 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.96934564 |
| 86 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.96630425 |
| 87 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.96489563 |
| 88 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.95335920 |
| 89 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.94316747 |
| 90 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.94106070 |
| 91 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.94096235 |
| 92 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.93948491 |
| 93 | JUN_21703547_ChIP-Seq_K562_Human | 0.93826648 |
| 94 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.93646504 |
| 95 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.93646504 |
| 96 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.93443009 |
| 97 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.93023332 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92455494 |
| 99 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.92196070 |
| 100 | NCOR_22424771_ChIP-Seq_293T_Human | 0.92175875 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003880_abnormal_central_pattern | 9.39742017 |
| 2 | MP0005671_abnormal_response_to | 2.78857761 |
| 3 | MP0002102_abnormal_ear_morphology | 2.76679515 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.75457875 |
| 5 | MP0008995_early_reproductive_senescence | 2.74179019 |
| 6 | MP0003136_yellow_coat_color | 2.67233837 |
| 7 | MP0009379_abnormal_foot_pigmentation | 2.26247304 |
| 8 | MP0002653_abnormal_ependyma_morphology | 2.24805460 |
| 9 | MP0005084_abnormal_gallbladder_morpholo | 2.13768178 |
| 10 | MP0003938_abnormal_ear_development | 2.00491471 |
| 11 | MP0004145_abnormal_muscle_electrophysio | 1.99853077 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 1.92837162 |
| 13 | MP0004142_abnormal_muscle_tone | 1.84038624 |
| 14 | MP0006292_abnormal_olfactory_placode | 1.78896912 |
| 15 | MP0003183_abnormal_peptide_metabolism | 1.58347848 |
| 16 | MP0005551_abnormal_eye_electrophysiolog | 1.57990983 |
| 17 | MP0002822_catalepsy | 1.57755763 |
| 18 | MP0009046_muscle_twitch | 1.56675026 |
| 19 | MP0003786_premature_aging | 1.48569037 |
| 20 | MP0002234_abnormal_pharynx_morphology | 1.48127358 |
| 21 | MP0001986_abnormal_taste_sensitivity | 1.48110381 |
| 22 | MP0001485_abnormal_pinna_reflex | 1.45326820 |
| 23 | MP0005253_abnormal_eye_physiology | 1.44810085 |
| 24 | MP0002163_abnormal_gland_morphology | 1.43555408 |
| 25 | MP0002277_abnormal_respiratory_mucosa | 1.41035264 |
| 26 | MP0002638_abnormal_pupillary_reflex | 1.38045386 |
| 27 | MP0001800_abnormal_humoral_immune | 1.37694021 |
| 28 | MP0000026_abnormal_inner_ear | 1.37304231 |
| 29 | MP0008877_abnormal_DNA_methylation | 1.36691501 |
| 30 | MP0003283_abnormal_digestive_organ | 1.35224102 |
| 31 | MP0002751_abnormal_autonomic_nervous | 1.32146236 |
| 32 | MP0003646_muscle_fatigue | 1.31038335 |
| 33 | MP0003011_delayed_dark_adaptation | 1.23924932 |
| 34 | MP0002876_abnormal_thyroid_physiology | 1.23867920 |
| 35 | MP0004147_increased_porphyrin_level | 1.20798736 |
| 36 | MP0002184_abnormal_innervation | 1.20606078 |
| 37 | MP0008789_abnormal_olfactory_epithelium | 1.20523015 |
| 38 | MP0001529_abnormal_vocalization | 1.17181779 |
| 39 | MP0002166_altered_tumor_susceptibility | 1.17019473 |
| 40 | MP0002272_abnormal_nervous_system | 1.14499991 |
| 41 | MP0008872_abnormal_physiological_respon | 1.14172253 |
| 42 | MP0006036_abnormal_mitochondrial_physio | 1.12732573 |
| 43 | MP0001790_abnormal_immune_system | 1.12601450 |
| 44 | MP0005387_immune_system_phenotype | 1.12601450 |
| 45 | MP0009333_abnormal_splenocyte_physiolog | 1.11576979 |
| 46 | MP0000631_abnormal_neuroendocrine_gland | 1.08682000 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.08111979 |
| 48 | MP0000685_abnormal_immune_system | 1.06495541 |
| 49 | MP0009785_altered_susceptibility_to | 1.05666571 |
| 50 | MP0003950_abnormal_plasma_membrane | 1.05383043 |
| 51 | MP0008961_abnormal_basal_metabolism | 1.02354602 |
| 52 | MP0001764_abnormal_homeostasis | 1.02157296 |
| 53 | MP0000778_abnormal_nervous_system | 0.95933992 |
| 54 | MP0001188_hyperpigmentation | 0.95679336 |
| 55 | MP0001905_abnormal_dopamine_level | 0.93558354 |
| 56 | MP0002282_abnormal_trachea_morphology | 0.93086516 |
| 57 | MP0005000_abnormal_immune_tolerance | 0.93006096 |
| 58 | MP0000955_abnormal_spinal_cord | 0.92628047 |
| 59 | MP0002095_abnormal_skin_pigmentation | 0.92538829 |
| 60 | MP0005075_abnormal_melanosome_morpholog | 0.92355555 |
| 61 | MP0000427_abnormal_hair_cycle | 0.91238501 |
| 62 | MP0002928_abnormal_bile_duct | 0.90135220 |
| 63 | MP0002006_tumorigenesis | 0.89546341 |
| 64 | MP0001486_abnormal_startle_reflex | 0.89339825 |
| 65 | MP0009745_abnormal_behavioral_response | 0.89300824 |
| 66 | MP0002148_abnormal_hypersensitivity_rea | 0.87548294 |
| 67 | MP0004133_heterotaxia | 0.86662587 |
| 68 | MP0005195_abnormal_posterior_eye | 0.84536218 |
| 69 | MP0004885_abnormal_endolymph | 0.84029199 |
| 70 | MP0002723_abnormal_immune_serum | 0.82272006 |
| 71 | MP0001293_anophthalmia | 0.81292034 |
| 72 | MP0002572_abnormal_emotion/affect_behav | 0.79179568 |
| 73 | MP0001119_abnormal_female_reproductive | 0.78852025 |
| 74 | MP0006035_abnormal_mitochondrial_morpho | 0.78436150 |
| 75 | MP0001346_abnormal_lacrimal_gland | 0.77667077 |
| 76 | MP0003787_abnormal_imprinting | 0.76435292 |
| 77 | MP0000383_abnormal_hair_follicle | 0.75023273 |
| 78 | MP0002420_abnormal_adaptive_immunity | 0.74579425 |
| 79 | MP0003724_increased_susceptibility_to | 0.74466982 |
| 80 | MP0002752_abnormal_somatic_nervous | 0.73812888 |
| 81 | MP0005499_abnormal_olfactory_system | 0.72212948 |
| 82 | MP0005394_taste/olfaction_phenotype | 0.72212948 |
| 83 | MP0002452_abnormal_antigen_presenting | 0.71941279 |
| 84 | MP0002736_abnormal_nociception_after | 0.71926470 |
| 85 | MP0001970_abnormal_pain_threshold | 0.71750713 |
| 86 | MP0001819_abnormal_immune_cell | 0.71444228 |
| 87 | MP0009764_decreased_sensitivity_to | 0.70787798 |
| 88 | MP0001286_abnormal_eye_development | 0.69965473 |
| 89 | MP0002064_seizures | 0.69017099 |
| 90 | MP0003879_abnormal_hair_cell | 0.68459118 |
| 91 | MP0004215_abnormal_myocardial_fiber | 0.64306333 |
| 92 | MP0003635_abnormal_synaptic_transmissio | 0.64018234 |
| 93 | MP0001765_abnormal_ion_homeostasis | 0.63583339 |
| 94 | MP0006276_abnormal_autonomic_nervous | 0.63529030 |
| 95 | MP0002735_abnormal_chemical_nociception | 0.63131062 |
| 96 | MP0009250_abnormal_appendicular_skeleto | 0.62578634 |
| 97 | MP0005379_endocrine/exocrine_gland_phen | 0.62180723 |
| 98 | MP0001984_abnormal_olfaction | 0.61631850 |
| 99 | MP0005025_abnormal_response_to | 0.60561086 |
| 100 | MP0005646_abnormal_pituitary_gland | 0.60525287 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oligodactyly (hands) (HP:0001180) | 5.93128748 |
| 2 | Fibular aplasia (HP:0002990) | 5.30064406 |
| 3 | Hypoplastic pelvis (HP:0008839) | 4.85658694 |
| 4 | Oligodactyly (HP:0012165) | 4.28373377 |
| 5 | Split foot (HP:0001839) | 4.08112038 |
| 6 | Synostosis involving the elbow (HP:0003938) | 3.97892507 |
| 7 | Humeroradial synostosis (HP:0003041) | 3.97892507 |
| 8 | Aplasia/hypoplasia of the uterus (HP:0008684) | 3.91855788 |
| 9 | Adactyly (HP:0009776) | 3.78334096 |
| 10 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 3.69401621 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.52293970 |
| 12 | Acute necrotizing encephalopathy (HP:0006965) | 3.51167571 |
| 13 | Absent/shortened dynein arms (HP:0200106) | 3.49677176 |
| 14 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.49677176 |
| 15 | Increased CSF lactate (HP:0002490) | 3.45802192 |
| 16 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 3.39569031 |
| 17 | Chronic sinusitis (HP:0011109) | 3.32312762 |
| 18 | Radial bowing (HP:0002986) | 3.20227918 |
| 19 | Congenital stationary night blindness (HP:0007642) | 3.08683131 |
| 20 | Progressive macrocephaly (HP:0004481) | 3.00960560 |
| 21 | Abnormal finger flexion creases (HP:0006143) | 2.99435316 |
| 22 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.95131226 |
| 23 | Acute encephalopathy (HP:0006846) | 2.89075661 |
| 24 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.87890884 |
| 25 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.85942683 |
| 26 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.85942683 |
| 27 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.85119243 |
| 28 | Abnormal ciliary motility (HP:0012262) | 2.82994214 |
| 29 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.81398332 |
| 30 | Increased hepatocellular lipid droplets (HP:0006565) | 2.79679650 |
| 31 | Hepatocellular necrosis (HP:0001404) | 2.69396929 |
| 32 | Lipid accumulation in hepatocytes (HP:0006561) | 2.63334276 |
| 33 | Abnormality of midbrain morphology (HP:0002418) | 2.61392948 |
| 34 | Molar tooth sign on MRI (HP:0002419) | 2.61392948 |
| 35 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.56790102 |
| 36 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.56790102 |
| 37 | Hypoplastic nipples (HP:0002557) | 2.48670068 |
| 38 | Supernumerary spleens (HP:0009799) | 2.48544790 |
| 39 | Myokymia (HP:0002411) | 2.45432880 |
| 40 | Barrel-shaped chest (HP:0001552) | 2.40312948 |
| 41 | Hypoplasia of the radius (HP:0002984) | 2.39742873 |
| 42 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.39074230 |
| 43 | Renal Fanconi syndrome (HP:0001994) | 2.35740032 |
| 44 | Increased IgM level (HP:0003496) | 2.33328502 |
| 45 | Alveolar cell carcinoma (HP:0006519) | 2.32192868 |
| 46 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 2.29870311 |
| 47 | Type II lissencephaly (HP:0007260) | 2.29250807 |
| 48 | Cerebral edema (HP:0002181) | 2.27096020 |
| 49 | Large eyes (HP:0001090) | 2.26307410 |
| 50 | Abnormality of the pubic bones (HP:0003172) | 2.25112388 |
| 51 | Broad ribs (HP:0000885) | 2.22165778 |
| 52 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.20535318 |
| 53 | Hemivertebrae (HP:0002937) | 2.18701621 |
| 54 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.18124116 |
| 55 | Forearm undergrowth (HP:0009821) | 2.15859162 |
| 56 | Hepatic necrosis (HP:0002605) | 2.15188314 |
| 57 | Abolished electroretinogram (ERG) (HP:0000550) | 2.15019607 |
| 58 | Azoospermia (HP:0000027) | 2.14388729 |
| 59 | Increased serum lactate (HP:0002151) | 2.13981600 |
| 60 | Aplasia involving forearm bones (HP:0009822) | 2.12662341 |
| 61 | Absent forearm bone (HP:0003953) | 2.12662341 |
| 62 | Optic disc pallor (HP:0000543) | 2.10603912 |
| 63 | IgG deficiency (HP:0004315) | 2.05729278 |
| 64 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 2.01676415 |
| 65 | Increased intramyocellular lipid droplets (HP:0012240) | 1.97995044 |
| 66 | Pancreatic cysts (HP:0001737) | 1.95576604 |
| 67 | Abnormal spermatogenesis (HP:0008669) | 1.94750504 |
| 68 | Hypoplastic iliac wings (HP:0002866) | 1.94059237 |
| 69 | Hypothermia (HP:0002045) | 1.94047072 |
| 70 | 3-Methylglutaconic aciduria (HP:0003535) | 1.92043964 |
| 71 | Rib fusion (HP:0000902) | 1.91956188 |
| 72 | Exertional dyspnea (HP:0002875) | 1.90979237 |
| 73 | Hypoproteinemia (HP:0003075) | 1.90436760 |
| 74 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.90299023 |
| 75 | B lymphocytopenia (HP:0010976) | 1.88752368 |
| 76 | Abnormality of B cell number (HP:0010975) | 1.88327676 |
| 77 | Recurrent bronchitis (HP:0002837) | 1.86767079 |
| 78 | Decreased circulating renin level (HP:0003351) | 1.85335850 |
| 79 | Bowing of the arm (HP:0006488) | 1.83941987 |
| 80 | Bowed forearm bones (HP:0003956) | 1.83941987 |
| 81 | Bronchitis (HP:0012387) | 1.83568035 |
| 82 | Patellar aplasia (HP:0006443) | 1.81102789 |
| 83 | Chronic bronchitis (HP:0004469) | 1.78914880 |
| 84 | True hermaphroditism (HP:0010459) | 1.76588923 |
| 85 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.76422572 |
| 86 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.74980497 |
| 87 | Septo-optic dysplasia (HP:0100842) | 1.73391611 |
| 88 | Pancreatic fibrosis (HP:0100732) | 1.73246160 |
| 89 | Inability to walk (HP:0002540) | 1.73105682 |
| 90 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.70250998 |
| 91 | Postaxial hand polydactyly (HP:0001162) | 1.68960983 |
| 92 | Nephronophthisis (HP:0000090) | 1.68116047 |
| 93 | Lactic acidosis (HP:0003128) | 1.67705857 |
| 94 | Abnormality of macular pigmentation (HP:0008002) | 1.66480891 |
| 95 | Abnormality of T cell number (HP:0011839) | 1.66204181 |
| 96 | Increased muscle lipid content (HP:0009058) | 1.66202460 |
| 97 | Parakeratosis (HP:0001036) | 1.63352524 |
| 98 | Congenital, generalized hypertrichosis (HP:0004540) | 1.63144526 |
| 99 | Cystic liver disease (HP:0006706) | 1.62910774 |
| 100 | Stomatitis (HP:0010280) | 1.62890850 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BMPR2 | 4.65686535 |
| 2 | TAOK3 | 4.08683596 |
| 3 | TXK | 3.74449033 |
| 4 | TNIK | 3.34068421 |
| 5 | CDK19 | 3.23642290 |
| 6 | MAP4K2 | 2.44483463 |
| 7 | MAP3K12 | 2.38462997 |
| 8 | TLK1 | 2.34508873 |
| 9 | WNK4 | 2.30665955 |
| 10 | ERBB3 | 2.27944673 |
| 11 | MUSK | 2.07451747 |
| 12 | PINK1 | 1.97479385 |
| 13 | SCYL2 | 1.88625482 |
| 14 | GRK1 | 1.80224846 |
| 15 | WNK3 | 1.71436612 |
| 16 | ADRBK2 | 1.70429722 |
| 17 | MAP4K1 | 1.59723782 |
| 18 | EIF2AK1 | 1.51829323 |
| 19 | VRK2 | 1.40062350 |
| 20 | STK39 | 1.38630042 |
| 21 | RIPK4 | 1.37330615 |
| 22 | EIF2AK3 | 1.30439270 |
| 23 | MYLK | 1.29652649 |
| 24 | TSSK6 | 1.28881126 |
| 25 | AKT3 | 1.28622852 |
| 26 | ZAK | 1.24322049 |
| 27 | KDR | 1.23474662 |
| 28 | ILK | 1.23360098 |
| 29 | STK38L | 1.14395189 |
| 30 | VRK1 | 1.10114915 |
| 31 | BMPR1B | 1.09601321 |
| 32 | MAP2K7 | 1.08583885 |
| 33 | CDK8 | 1.07729222 |
| 34 | PKN1 | 1.03781935 |
| 35 | CAMKK2 | 1.01452921 |
| 36 | SYK | 1.00740532 |
| 37 | STK16 | 1.00241666 |
| 38 | OXSR1 | 0.97599351 |
| 39 | MAP2K6 | 0.95750544 |
| 40 | IKBKB | 0.93170858 |
| 41 | DYRK2 | 0.91771503 |
| 42 | GRK7 | 0.91510258 |
| 43 | MAPK15 | 0.91159682 |
| 44 | BCR | 0.89164929 |
| 45 | TEC | 0.88374952 |
| 46 | MAP3K4 | 0.88333492 |
| 47 | FRK | 0.83332399 |
| 48 | OBSCN | 0.79040664 |
| 49 | PIK3CG | 0.74228229 |
| 50 | CSF1R | 0.73816824 |
| 51 | ITK | 0.71064735 |
| 52 | INSRR | 0.70845082 |
| 53 | MAPK13 | 0.70072366 |
| 54 | LYN | 0.68263891 |
| 55 | TRPM7 | 0.67228117 |
| 56 | SRPK1 | 0.59988437 |
| 57 | BTK | 0.59807468 |
| 58 | LCK | 0.59579193 |
| 59 | EIF2AK2 | 0.59078140 |
| 60 | PLK4 | 0.56401713 |
| 61 | CCNB1 | 0.55935736 |
| 62 | ADRBK1 | 0.54425632 |
| 63 | IKBKE | 0.53521763 |
| 64 | DYRK1B | 0.53143724 |
| 65 | BCKDK | 0.53140887 |
| 66 | ERBB2 | 0.50115309 |
| 67 | FES | 0.49845527 |
| 68 | BRSK2 | 0.49379701 |
| 69 | PHKG2 | 0.49022340 |
| 70 | PHKG1 | 0.49022340 |
| 71 | ROCK1 | 0.48928646 |
| 72 | CAMK2A | 0.48724514 |
| 73 | PRKCQ | 0.48143202 |
| 74 | MST4 | 0.47828554 |
| 75 | PRKCG | 0.46624798 |
| 76 | PRKACA | 0.45005942 |
| 77 | TIE1 | 0.43053449 |
| 78 | HCK | 0.41117956 |
| 79 | PRKCA | 0.41024894 |
| 80 | PRKCE | 0.40153888 |
| 81 | IGF1R | 0.39223538 |
| 82 | NTRK2 | 0.39214127 |
| 83 | CAMK1 | 0.39121518 |
| 84 | GRK6 | 0.38313181 |
| 85 | PRKG1 | 0.38041171 |
| 86 | MARK3 | 0.37851720 |
| 87 | CASK | 0.37299434 |
| 88 | ABL1 | 0.36957892 |
| 89 | PRKCB | 0.36700610 |
| 90 | JAK3 | 0.35638784 |
| 91 | MINK1 | 0.35269286 |
| 92 | CSNK2A1 | 0.34282134 |
| 93 | TRIM28 | 0.33614466 |
| 94 | PLK3 | 0.33286318 |
| 95 | AURKB | 0.32988786 |
| 96 | CSK | 0.31327609 |
| 97 | PLK2 | 0.31214350 |
| 98 | CAMK2D | 0.30314311 |
| 99 | NEK1 | 0.29949988 |
| 100 | WNK1 | 0.28842587 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.09639796 |
| 2 | Parkinsons disease_Homo sapiens_hsa05012 | 3.93528055 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.77106200 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.43872680 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.04320481 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.94828506 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.93464424 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.87840744 |
| 9 | Ribosome_Homo sapiens_hsa03010 | 2.64673898 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.47667692 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.45378046 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.24964862 |
| 13 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.19772529 |
| 14 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.17569093 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.96294026 |
| 16 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.80855295 |
| 17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.79661104 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.78123027 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.77223825 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.72561102 |
| 21 | RNA polymerase_Homo sapiens_hsa03020 | 1.68998279 |
| 22 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.64386301 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.50418776 |
| 24 | Viral myocarditis_Homo sapiens_hsa05416 | 1.25042926 |
| 25 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.22932026 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.18587003 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.14649098 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.14435172 |
| 29 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.14249594 |
| 30 | Morphine addiction_Homo sapiens_hsa05032 | 1.13998485 |
| 31 | Nicotine addiction_Homo sapiens_hsa05033 | 1.12105507 |
| 32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.11649202 |
| 33 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.05512834 |
| 34 | Homologous recombination_Homo sapiens_hsa03440 | 1.05295309 |
| 35 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.02925502 |
| 36 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.98041204 |
| 37 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.95891273 |
| 38 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.93945354 |
| 39 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.93261292 |
| 40 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.92726799 |
| 41 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.90951257 |
| 42 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.90356983 |
| 43 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.88975784 |
| 44 | Olfactory transduction_Homo sapiens_hsa04740 | 0.87781483 |
| 45 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.83510683 |
| 46 | RNA degradation_Homo sapiens_hsa03018 | 0.79706630 |
| 47 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.77530701 |
| 48 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.76275927 |
| 49 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.76082941 |
| 50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.71277204 |
| 51 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.69871815 |
| 52 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.68174321 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.66975400 |
| 54 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.63009470 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.62366501 |
| 56 | Purine metabolism_Homo sapiens_hsa00230 | 0.61516609 |
| 57 | Cocaine addiction_Homo sapiens_hsa05030 | 0.61292018 |
| 58 | Taste transduction_Homo sapiens_hsa04742 | 0.58992523 |
| 59 | Peroxisome_Homo sapiens_hsa04146 | 0.56869796 |
| 60 | Leishmaniasis_Homo sapiens_hsa05140 | 0.54329594 |
| 61 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.53501679 |
| 62 | GABAergic synapse_Homo sapiens_hsa04727 | 0.51356411 |
| 63 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.50367830 |
| 64 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.50333797 |
| 65 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.46614532 |
| 66 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.44421895 |
| 67 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.42229287 |
| 68 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41962673 |
| 69 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.37815756 |
| 70 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.37661343 |
| 71 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.37629614 |
| 72 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.37220458 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.36953231 |
| 74 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.36702988 |
| 75 | Tuberculosis_Homo sapiens_hsa05152 | 0.35400652 |
| 76 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.34875670 |
| 77 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.34779911 |
| 78 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.33546097 |
| 79 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.33346530 |
| 80 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.33156259 |
| 81 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32351104 |
| 82 | Circadian entrainment_Homo sapiens_hsa04713 | 0.31960380 |
| 83 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.30493187 |
| 84 | Axon guidance_Homo sapiens_hsa04360 | 0.27394833 |
| 85 | Spliceosome_Homo sapiens_hsa03040 | 0.27101323 |
| 86 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.26531710 |
| 87 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.26399618 |
| 88 | Insulin secretion_Homo sapiens_hsa04911 | 0.25134029 |
| 89 | Alcoholism_Homo sapiens_hsa05034 | 0.24384009 |
| 90 | Phagosome_Homo sapiens_hsa04145 | 0.23268624 |
| 91 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.22826657 |
| 92 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.22622403 |
| 93 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.20743887 |
| 94 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.20426332 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.19929769 |
| 96 | Base excision repair_Homo sapiens_hsa03410 | 0.18862171 |
| 97 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.17976320 |
| 98 | DNA replication_Homo sapiens_hsa03030 | 0.17465554 |
| 99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.16831320 |
| 100 | Legionellosis_Homo sapiens_hsa05134 | 0.16326311 |

