

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.23348953 |
| 2 | proteasome assembly (GO:0043248) | 5.14610636 |
| 3 | DNA double-strand break processing (GO:0000729) | 4.86265341 |
| 4 | protein deneddylation (GO:0000338) | 4.76615674 |
| 5 | cullin deneddylation (GO:0010388) | 4.63753278 |
| 6 | protein neddylation (GO:0045116) | 4.55567666 |
| 7 | respiratory chain complex IV assembly (GO:0008535) | 4.40824206 |
| 8 | maturation of 5.8S rRNA (GO:0000460) | 4.32425105 |
| 9 | protein complex biogenesis (GO:0070271) | 4.23330377 |
| 10 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.09908144 |
| 11 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.04818048 |
| 12 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.02168429 |
| 13 | cytochrome complex assembly (GO:0017004) | 4.01553744 |
| 14 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.69865177 |
| 15 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.69766103 |
| 16 | DNA ligation (GO:0006266) | 3.60679154 |
| 17 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.60521835 |
| 18 | NADH dehydrogenase complex assembly (GO:0010257) | 3.60521835 |
| 19 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.60521835 |
| 20 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.55990863 |
| 21 | succinate metabolic process (GO:0006105) | 3.55074520 |
| 22 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.54484749 |
| 23 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.51401263 |
| 24 | histone H2A acetylation (GO:0043968) | 3.48949371 |
| 25 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.48507200 |
| 26 | cellular ketone body metabolic process (GO:0046950) | 3.48072786 |
| 27 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.45229732 |
| 28 | regulation of mitochondrial translation (GO:0070129) | 3.42175083 |
| 29 | chaperone-mediated protein transport (GO:0072321) | 3.38009789 |
| 30 | platelet dense granule organization (GO:0060155) | 3.37340953 |
| 31 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.36663143 |
| 32 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.36663143 |
| 33 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.31087600 |
| 34 | negative regulation of ligase activity (GO:0051352) | 3.31087600 |
| 35 | cytidine deamination (GO:0009972) | 3.29309437 |
| 36 | cytidine metabolic process (GO:0046087) | 3.29309437 |
| 37 | cytidine catabolic process (GO:0006216) | 3.29309437 |
| 38 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.23059846 |
| 39 | DNA damage response, detection of DNA damage (GO:0042769) | 3.22877667 |
| 40 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.20523911 |
| 41 | ketone body metabolic process (GO:1902224) | 3.19714326 |
| 42 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.18153836 |
| 43 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.17989031 |
| 44 | rRNA modification (GO:0000154) | 3.16702826 |
| 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.15695654 |
| 46 | mannosylation (GO:0097502) | 3.15110417 |
| 47 | ATP synthesis coupled proton transport (GO:0015986) | 3.13205102 |
| 48 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.13205102 |
| 49 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.13020275 |
| 50 | branched-chain amino acid catabolic process (GO:0009083) | 3.11182648 |
| 51 | protein-cofactor linkage (GO:0018065) | 3.09837483 |
| 52 | peptidyl-cysteine modification (GO:0018198) | 3.09478373 |
| 53 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.08603437 |
| 54 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.08603437 |
| 55 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.08603437 |
| 56 | L-methionine salvage (GO:0071267) | 3.07051181 |
| 57 | L-methionine biosynthetic process (GO:0071265) | 3.07051181 |
| 58 | amino acid salvage (GO:0043102) | 3.07051181 |
| 59 | tricarboxylic acid cycle (GO:0006099) | 3.06139334 |
| 60 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.05548807 |
| 61 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.05548807 |
| 62 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.05505601 |
| 63 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.05505601 |
| 64 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.05286882 |
| 65 | isotype switching (GO:0045190) | 3.05286882 |
| 66 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.05286882 |
| 67 | iron-sulfur cluster assembly (GO:0016226) | 3.05137226 |
| 68 | metallo-sulfur cluster assembly (GO:0031163) | 3.05137226 |
| 69 | respiratory electron transport chain (GO:0022904) | 3.04614568 |
| 70 | negative regulation of DNA recombination (GO:0045910) | 3.01428036 |
| 71 | electron transport chain (GO:0022900) | 2.99553154 |
| 72 | negative regulation of membrane potential (GO:0045837) | 2.99173482 |
| 73 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.99130663 |
| 74 | ubiquinone biosynthetic process (GO:0006744) | 2.98858245 |
| 75 | histone mRNA metabolic process (GO:0008334) | 2.94057448 |
| 76 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.93608826 |
| 77 | amino acid activation (GO:0043038) | 2.92392699 |
| 78 | tRNA aminoacylation (GO:0043039) | 2.92392699 |
| 79 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.91011270 |
| 80 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.91011270 |
| 81 | ribonucleoprotein complex disassembly (GO:0032988) | 2.89549131 |
| 82 | positive regulation of ligase activity (GO:0051351) | 2.89147891 |
| 83 | tRNA aminoacylation for protein translation (GO:0006418) | 2.87814985 |
| 84 | ubiquinone metabolic process (GO:0006743) | 2.82412077 |
| 85 | ribosome assembly (GO:0042255) | 2.81927091 |
| 86 | protein refolding (GO:0042026) | 2.81379052 |
| 87 | rRNA methylation (GO:0031167) | 2.79864168 |
| 88 | tRNA metabolic process (GO:0006399) | 2.78558743 |
| 89 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.77701169 |
| 90 | spliceosomal snRNP assembly (GO:0000387) | 2.77387147 |
| 91 | organelle disassembly (GO:1903008) | 2.77196051 |
| 92 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.76149861 |
| 93 | termination of RNA polymerase III transcription (GO:0006386) | 2.76149861 |
| 94 | regulation of helicase activity (GO:0051095) | 2.75254963 |
| 95 | establishment of integrated proviral latency (GO:0075713) | 2.72720366 |
| 96 | tRNA processing (GO:0008033) | 2.72444535 |
| 97 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.72404467 |
| 98 | inner mitochondrial membrane organization (GO:0007007) | 2.72363870 |
| 99 | replication fork processing (GO:0031297) | 2.72211298 |
| 100 | positive regulation of mitochondrial fission (GO:0090141) | 2.71888824 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.65239670 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.42963233 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.13080669 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.29666808 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.03748075 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.92893722 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.88971535 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.81367793 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.62278545 |
| 10 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.54264554 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.42950550 |
| 12 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.42817818 |
| 13 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.40825434 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.36691886 |
| 15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.33092023 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.33008580 |
| 17 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.28823391 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.23274463 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.17531381 |
| 20 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.12245019 |
| 21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.02308754 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.01395426 |
| 23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.97807018 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.95736549 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.91958626 |
| 26 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.87223256 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84055789 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.77562603 |
| 29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.76105875 |
| 30 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.74865622 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.69266025 |
| 32 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.69053580 |
| 33 | P300_19829295_ChIP-Seq_ESCs_Human | 1.68544172 |
| 34 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.68538715 |
| 35 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.65657363 |
| 36 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.65086109 |
| 37 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.52000312 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.51102090 |
| 39 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.46039891 |
| 40 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.45131017 |
| 41 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.44453707 |
| 42 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.39873912 |
| 43 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.39823443 |
| 44 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.39246554 |
| 45 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.38316158 |
| 46 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.38107526 |
| 47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.30487414 |
| 48 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.29276816 |
| 49 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.28547881 |
| 50 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.28041140 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.27118156 |
| 52 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.24200344 |
| 53 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.23289309 |
| 54 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.20971015 |
| 55 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.20862188 |
| 56 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.20707104 |
| 57 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.19595078 |
| 58 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.18432308 |
| 59 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.16817788 |
| 60 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.15995616 |
| 61 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.15065775 |
| 62 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.14836959 |
| 63 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.14836959 |
| 64 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.14085009 |
| 65 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.12929032 |
| 66 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.12715251 |
| 67 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.12607740 |
| 68 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.12607740 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.12392252 |
| 70 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.11483428 |
| 71 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.11007841 |
| 72 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.09593266 |
| 73 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.08948035 |
| 74 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.08890196 |
| 75 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.08763940 |
| 76 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.08763940 |
| 77 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.08093118 |
| 78 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.06400296 |
| 79 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.05185226 |
| 80 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.04478412 |
| 81 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.04368695 |
| 82 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.03716751 |
| 83 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.98523085 |
| 84 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.98226974 |
| 85 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.95666935 |
| 86 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.94922096 |
| 87 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.94810001 |
| 88 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.93995333 |
| 89 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.93605607 |
| 90 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.93418228 |
| 91 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.93286854 |
| 92 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.89850314 |
| 93 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.89711255 |
| 94 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.89501962 |
| 95 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.88746456 |
| 96 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.88712505 |
| 97 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.88575153 |
| 98 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.86744997 |
| 99 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.86741053 |
| 100 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.86450418 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 3.16106865 |
| 2 | MP0002822_catalepsy | 3.09666467 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 3.01713478 |
| 4 | MP0008058_abnormal_DNA_repair | 2.99608297 |
| 5 | MP0003693_abnormal_embryo_hatching | 2.57176015 |
| 6 | MP0003880_abnormal_central_pattern | 2.50575419 |
| 7 | MP0001529_abnormal_vocalization | 2.50035122 |
| 8 | MP0002102_abnormal_ear_morphology | 2.48904952 |
| 9 | MP0004147_increased_porphyrin_level | 2.41569283 |
| 10 | MP0002837_dystrophic_cardiac_calcinosis | 2.40430916 |
| 11 | MP0010094_abnormal_chromosome_stability | 2.35949423 |
| 12 | MP0006035_abnormal_mitochondrial_morpho | 2.23292502 |
| 13 | MP0003195_calcinosis | 2.14603496 |
| 14 | MP0006036_abnormal_mitochondrial_physio | 2.13126571 |
| 15 | MP0002638_abnormal_pupillary_reflex | 2.06530409 |
| 16 | MP0005551_abnormal_eye_electrophysiolog | 1.96212795 |
| 17 | MP0006276_abnormal_autonomic_nervous | 1.92840825 |
| 18 | MP0005253_abnormal_eye_physiology | 1.92601188 |
| 19 | MP0003786_premature_aging | 1.88592996 |
| 20 | MP0001984_abnormal_olfaction | 1.87544254 |
| 21 | MP0003806_abnormal_nucleotide_metabolis | 1.85160703 |
| 22 | MP0004957_abnormal_blastocyst_morpholog | 1.76444866 |
| 23 | MP0004215_abnormal_myocardial_fiber | 1.73294549 |
| 24 | MP0005075_abnormal_melanosome_morpholog | 1.72755727 |
| 25 | MP0003718_maternal_effect | 1.62829893 |
| 26 | MP0003011_delayed_dark_adaptation | 1.59779339 |
| 27 | MP0001188_hyperpigmentation | 1.58116320 |
| 28 | MP0001485_abnormal_pinna_reflex | 1.56881755 |
| 29 | MP0009046_muscle_twitch | 1.55062882 |
| 30 | MP0006054_spinal_hemorrhage | 1.53813004 |
| 31 | MP0000372_irregular_coat_pigmentation | 1.49372644 |
| 32 | MP0003787_abnormal_imprinting | 1.46190081 |
| 33 | MP0001293_anophthalmia | 1.45337778 |
| 34 | MP0002751_abnormal_autonomic_nervous | 1.44721930 |
| 35 | MP0000427_abnormal_hair_cycle | 1.44669956 |
| 36 | MP0005645_abnormal_hypothalamus_physiol | 1.43218274 |
| 37 | MP0001486_abnormal_startle_reflex | 1.37341013 |
| 38 | MP0005367_renal/urinary_system_phenotyp | 1.33887663 |
| 39 | MP0000516_abnormal_urinary_system | 1.33887663 |
| 40 | MP0005084_abnormal_gallbladder_morpholo | 1.31395917 |
| 41 | MP0002163_abnormal_gland_morphology | 1.30782347 |
| 42 | MP0008932_abnormal_embryonic_tissue | 1.28854110 |
| 43 | MP0008789_abnormal_olfactory_epithelium | 1.28539112 |
| 44 | MP0002095_abnormal_skin_pigmentation | 1.26475938 |
| 45 | MP0002736_abnormal_nociception_after | 1.25610997 |
| 46 | MP0003186_abnormal_redox_activity | 1.24857993 |
| 47 | MP0008995_early_reproductive_senescence | 1.24161544 |
| 48 | MP0001764_abnormal_homeostasis | 1.22807569 |
| 49 | MP0004145_abnormal_muscle_electrophysio | 1.21173711 |
| 50 | MP0000358_abnormal_cell_content/ | 1.20704693 |
| 51 | MP0002735_abnormal_chemical_nociception | 1.20168164 |
| 52 | MP0009745_abnormal_behavioral_response | 1.18051736 |
| 53 | MP0001905_abnormal_dopamine_level | 1.13560587 |
| 54 | MP0005394_taste/olfaction_phenotype | 1.13455957 |
| 55 | MP0005499_abnormal_olfactory_system | 1.13455957 |
| 56 | MP0008775_abnormal_heart_ventricle | 1.13304037 |
| 57 | MP0003111_abnormal_nucleus_morphology | 1.12202584 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.11877868 |
| 59 | MP0001324_abnormal_eye_pigmentation | 1.09883354 |
| 60 | MP0008007_abnormal_cellular_replicative | 1.08779357 |
| 61 | MP0000749_muscle_degeneration | 1.07791150 |
| 62 | MP0002272_abnormal_nervous_system | 1.05479970 |
| 63 | MP0008875_abnormal_xenobiotic_pharmacok | 1.05355931 |
| 64 | MP0002909_abnormal_adrenal_gland | 1.01951120 |
| 65 | MP0002160_abnormal_reproductive_system | 1.00579121 |
| 66 | MP0000647_abnormal_sebaceous_gland | 1.00236721 |
| 67 | MP0001929_abnormal_gametogenesis | 0.99107217 |
| 68 | MP0005671_abnormal_response_to | 0.98207612 |
| 69 | MP0003121_genomic_imprinting | 0.97368077 |
| 70 | MP0005379_endocrine/exocrine_gland_phen | 0.97109636 |
| 71 | MP0001501_abnormal_sleep_pattern | 0.96865161 |
| 72 | MP0003878_abnormal_ear_physiology | 0.95464724 |
| 73 | MP0005377_hearing/vestibular/ear_phenot | 0.95464724 |
| 74 | MP0003122_maternal_imprinting | 0.93356292 |
| 75 | MP0000569_abnormal_digit_pigmentation | 0.92627597 |
| 76 | MP0006292_abnormal_olfactory_placode | 0.92361330 |
| 77 | MP0003890_abnormal_embryonic-extraembry | 0.92000980 |
| 78 | MP0002090_abnormal_vision | 0.91087246 |
| 79 | MP0003937_abnormal_limbs/digits/tail_de | 0.90070920 |
| 80 | MP0005389_reproductive_system_phenotype | 0.89005890 |
| 81 | MP0008057_abnormal_DNA_replication | 0.88546095 |
| 82 | MP0001968_abnormal_touch/_nociception | 0.88091198 |
| 83 | MP0005646_abnormal_pituitary_gland | 0.86319023 |
| 84 | MP0004885_abnormal_endolymph | 0.85510286 |
| 85 | MP0000015_abnormal_ear_pigmentation | 0.84649033 |
| 86 | MP0002277_abnormal_respiratory_mucosa | 0.84564461 |
| 87 | MP0009765_abnormal_xenobiotic_induced | 0.83248945 |
| 88 | MP0005332_abnormal_amino_acid | 0.82265057 |
| 89 | MP0004142_abnormal_muscle_tone | 0.82103197 |
| 90 | MP0002210_abnormal_sex_determination | 0.82071486 |
| 91 | MP0003567_abnormal_fetal_cardiomyocyte | 0.81952615 |
| 92 | MP0003137_abnormal_impulse_conducting | 0.81175243 |
| 93 | MP0003077_abnormal_cell_cycle | 0.80686575 |
| 94 | MP0003119_abnormal_digestive_system | 0.79920753 |
| 95 | MP0001986_abnormal_taste_sensitivity | 0.78721688 |
| 96 | MP0002752_abnormal_somatic_nervous | 0.77471736 |
| 97 | MP0000653_abnormal_sex_gland | 0.76981637 |
| 98 | MP0009785_altered_susceptibility_to | 0.74871529 |
| 99 | MP0000049_abnormal_middle_ear | 0.73765842 |
| 100 | MP0005195_abnormal_posterior_eye | 0.73596174 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 5.05946468 |
| 2 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 5.05946468 |
| 3 | Methylmalonic acidemia (HP:0002912) | 4.67661674 |
| 4 | Methylmalonic aciduria (HP:0012120) | 3.99909985 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.58553567 |
| 6 | Progressive inability to walk (HP:0002505) | 3.50006161 |
| 7 | Hepatic necrosis (HP:0002605) | 3.47349716 |
| 8 | Increased CSF lactate (HP:0002490) | 3.46197274 |
| 9 | Generalized aminoaciduria (HP:0002909) | 3.37172402 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.30724197 |
| 11 | 3-Methylglutaconic aciduria (HP:0003535) | 3.28496130 |
| 12 | Facial diplegia (HP:0001349) | 3.27736153 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.24348407 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.22650181 |
| 15 | Acute encephalopathy (HP:0006846) | 3.21771209 |
| 16 | Pancreatic cysts (HP:0001737) | 3.12094910 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.08248982 |
| 18 | Abnormality of the labia minora (HP:0012880) | 2.98622573 |
| 19 | Abnormality of vitamin B metabolism (HP:0004340) | 2.98226571 |
| 20 | Increased serum lactate (HP:0002151) | 2.97613466 |
| 21 | Renal cortical cysts (HP:0000803) | 2.95068231 |
| 22 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.93619428 |
| 23 | Increased hepatocellular lipid droplets (HP:0006565) | 2.82866667 |
| 24 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.72526276 |
| 25 | Abnormality of alanine metabolism (HP:0010916) | 2.72526276 |
| 26 | Hyperalaninemia (HP:0003348) | 2.72526276 |
| 27 | Lactic acidosis (HP:0003128) | 2.68922817 |
| 28 | Cerebral edema (HP:0002181) | 2.64445027 |
| 29 | Increased intramyocellular lipid droplets (HP:0012240) | 2.60909570 |
| 30 | True hermaphroditism (HP:0010459) | 2.60769361 |
| 31 | Type I transferrin isoform profile (HP:0003642) | 2.60320760 |
| 32 | Nephronophthisis (HP:0000090) | 2.53889129 |
| 33 | Lipid accumulation in hepatocytes (HP:0006561) | 2.53181703 |
| 34 | Medial flaring of the eyebrow (HP:0010747) | 2.50403075 |
| 35 | Hypothermia (HP:0002045) | 2.48899270 |
| 36 | Pancreatic fibrosis (HP:0100732) | 2.45719717 |
| 37 | Bile duct proliferation (HP:0001408) | 2.44643163 |
| 38 | Abnormal biliary tract physiology (HP:0012439) | 2.44643163 |
| 39 | Hypoglycemic coma (HP:0001325) | 2.42892536 |
| 40 | Increased serum pyruvate (HP:0003542) | 2.41536343 |
| 41 | Delayed gross motor development (HP:0002194) | 2.38117461 |
| 42 | Dicarboxylic aciduria (HP:0003215) | 2.37729644 |
| 43 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.37729644 |
| 44 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.35759582 |
| 45 | Abnormality of the renal cortex (HP:0011035) | 2.35133610 |
| 46 | Abnormality of glycolysis (HP:0004366) | 2.25790387 |
| 47 | Inability to walk (HP:0002540) | 2.24412847 |
| 48 | Keratoconus (HP:0000563) | 2.21353077 |
| 49 | Increased corneal curvature (HP:0100692) | 2.21353077 |
| 50 | Gaze-evoked nystagmus (HP:0000640) | 2.20982168 |
| 51 | Abnormality of midbrain morphology (HP:0002418) | 2.18562842 |
| 52 | Molar tooth sign on MRI (HP:0002419) | 2.18562842 |
| 53 | Glycosuria (HP:0003076) | 2.18550820 |
| 54 | Abnormality of urine glucose concentration (HP:0011016) | 2.18550820 |
| 55 | Palpitations (HP:0001962) | 2.12632345 |
| 56 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.12240259 |
| 57 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.12240259 |
| 58 | Abnormal protein glycosylation (HP:0012346) | 2.12240259 |
| 59 | Abnormal glycosylation (HP:0012345) | 2.12240259 |
| 60 | Colon cancer (HP:0003003) | 2.11907965 |
| 61 | Pendular nystagmus (HP:0012043) | 2.10843884 |
| 62 | Congenital stationary night blindness (HP:0007642) | 2.09892082 |
| 63 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.09696733 |
| 64 | Tongue fasciculations (HP:0001308) | 2.09600738 |
| 65 | Proximal tubulopathy (HP:0000114) | 2.08023738 |
| 66 | Optic disc pallor (HP:0000543) | 2.05311057 |
| 67 | Posterior subcapsular cataract (HP:0007787) | 2.03971758 |
| 68 | Abnormality of the ileum (HP:0001549) | 2.03303977 |
| 69 | Meckel diverticulum (HP:0002245) | 2.03196656 |
| 70 | Exercise intolerance (HP:0003546) | 2.02573353 |
| 71 | Poor suck (HP:0002033) | 2.01100787 |
| 72 | Carpal bone hypoplasia (HP:0001498) | 2.00205155 |
| 73 | Abnormality of the renal medulla (HP:0100957) | 1.99919000 |
| 74 | Gonadotropin excess (HP:0000837) | 1.99829508 |
| 75 | Increased muscle lipid content (HP:0009058) | 1.98708947 |
| 76 | Abnormality of vitamin metabolism (HP:0100508) | 1.97540485 |
| 77 | Nausea (HP:0002018) | 1.95220549 |
| 78 | Exertional dyspnea (HP:0002875) | 1.93521723 |
| 79 | Abnormality of the anterior horn cell (HP:0006802) | 1.93236590 |
| 80 | Degeneration of anterior horn cells (HP:0002398) | 1.93236590 |
| 81 | Renal Fanconi syndrome (HP:0001994) | 1.89566782 |
| 82 | Respiratory failure (HP:0002878) | 1.87457915 |
| 83 | Abolished electroretinogram (ERG) (HP:0000550) | 1.85811870 |
| 84 | Type 2 muscle fiber atrophy (HP:0003554) | 1.84948628 |
| 85 | Abnormality of serum amino acid levels (HP:0003112) | 1.84039222 |
| 86 | Congenital primary aphakia (HP:0007707) | 1.82291363 |
| 87 | Nephrogenic diabetes insipidus (HP:0009806) | 1.80498632 |
| 88 | Lethargy (HP:0001254) | 1.78254185 |
| 89 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.76688860 |
| 90 | Increased IgM level (HP:0003496) | 1.75772276 |
| 91 | Ketoacidosis (HP:0001993) | 1.74066734 |
| 92 | Gait imbalance (HP:0002141) | 1.73901326 |
| 93 | Abnormality of methionine metabolism (HP:0010901) | 1.71653580 |
| 94 | IgG deficiency (HP:0004315) | 1.70679468 |
| 95 | Delayed CNS myelination (HP:0002188) | 1.70441994 |
| 96 | Cutaneous melanoma (HP:0012056) | 1.68208201 |
| 97 | Sclerocornea (HP:0000647) | 1.67845597 |
| 98 | Neoplasm of the adrenal gland (HP:0100631) | 1.66389354 |
| 99 | Hyperglycinemia (HP:0002154) | 1.64702160 |
| 100 | Hypoproteinemia (HP:0003075) | 1.64464369 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRIM28 | 3.76704842 |
| 2 | BCR | 3.17785078 |
| 3 | MAP4K2 | 2.95641781 |
| 4 | TSSK6 | 2.94447444 |
| 5 | WNK3 | 2.64038513 |
| 6 | NEK1 | 2.63330078 |
| 7 | SRPK1 | 2.63116894 |
| 8 | EIF2AK3 | 2.52140150 |
| 9 | PINK1 | 2.42607351 |
| 10 | NUAK1 | 2.35068448 |
| 11 | MKNK2 | 2.31332412 |
| 12 | MST4 | 2.30166513 |
| 13 | BCKDK | 2.26099202 |
| 14 | BUB1 | 2.17191200 |
| 15 | EIF2AK1 | 2.04883460 |
| 16 | ZAK | 1.83793212 |
| 17 | MKNK1 | 1.81715303 |
| 18 | TLK1 | 1.78435592 |
| 19 | INSRR | 1.78086001 |
| 20 | ACVR1B | 1.77726561 |
| 21 | TXK | 1.76258373 |
| 22 | FRK | 1.70201288 |
| 23 | CSNK1G3 | 1.68891230 |
| 24 | PLK3 | 1.63718457 |
| 25 | GRK1 | 1.62051780 |
| 26 | CSNK1G1 | 1.54267887 |
| 27 | ADRBK2 | 1.50411326 |
| 28 | CSNK1G2 | 1.45789541 |
| 29 | ERBB3 | 1.35942080 |
| 30 | OXSR1 | 1.28708763 |
| 31 | MAP3K12 | 1.27318211 |
| 32 | CSNK1A1L | 1.26338973 |
| 33 | CDK19 | 1.24755917 |
| 34 | PLK4 | 1.21798574 |
| 35 | DAPK2 | 1.20074881 |
| 36 | BMPR1B | 1.18348214 |
| 37 | MAP2K6 | 1.09741622 |
| 38 | VRK2 | 1.09440195 |
| 39 | PLK2 | 1.06035450 |
| 40 | PDK2 | 1.05224778 |
| 41 | MAPK13 | 1.04996094 |
| 42 | SIK3 | 1.04794270 |
| 43 | TTK | 1.02971137 |
| 44 | WNK4 | 1.01657124 |
| 45 | CDC7 | 1.00372674 |
| 46 | TAF1 | 0.95579759 |
| 47 | MAPKAPK5 | 0.94163848 |
| 48 | PLK1 | 0.93383437 |
| 49 | NEK2 | 0.87665559 |
| 50 | BRSK2 | 0.83568585 |
| 51 | TNIK | 0.80099878 |
| 52 | STK39 | 0.79207061 |
| 53 | STK16 | 0.78947216 |
| 54 | WEE1 | 0.78115523 |
| 55 | PHKG1 | 0.77666788 |
| 56 | PHKG2 | 0.77666788 |
| 57 | CAMKK2 | 0.74798176 |
| 58 | PBK | 0.74202726 |
| 59 | VRK1 | 0.74010232 |
| 60 | PRKCG | 0.73934592 |
| 61 | SIK2 | 0.73877063 |
| 62 | KDR | 0.69282245 |
| 63 | PAK3 | 0.65464559 |
| 64 | EIF2AK2 | 0.65197013 |
| 65 | DYRK2 | 0.63925819 |
| 66 | LIMK1 | 0.60277012 |
| 67 | STK24 | 0.59498682 |
| 68 | NME1 | 0.58546376 |
| 69 | ALK | 0.57801890 |
| 70 | PRKCE | 0.54438503 |
| 71 | ATR | 0.53523860 |
| 72 | AURKB | 0.50595857 |
| 73 | BRSK1 | 0.48551394 |
| 74 | CSNK1A1 | 0.47128428 |
| 75 | MUSK | 0.44950656 |
| 76 | PNCK | 0.44524214 |
| 77 | MINK1 | 0.43925414 |
| 78 | CSNK2A1 | 0.42391120 |
| 79 | CCNB1 | 0.41723286 |
| 80 | MAP2K7 | 0.41309019 |
| 81 | TIE1 | 0.41083198 |
| 82 | OBSCN | 0.40158524 |
| 83 | GRK7 | 0.39586462 |
| 84 | ATM | 0.39445663 |
| 85 | MAP3K4 | 0.39306675 |
| 86 | FER | 0.38055456 |
| 87 | TGFBR1 | 0.38005841 |
| 88 | CDK3 | 0.37363903 |
| 89 | ILK | 0.37343951 |
| 90 | CAMK2A | 0.36144059 |
| 91 | DAPK1 | 0.36055298 |
| 92 | BMPR2 | 0.35107973 |
| 93 | RPS6KA5 | 0.34589402 |
| 94 | PRKCQ | 0.32427686 |
| 95 | IGF1R | 0.31937066 |
| 96 | EGFR | 0.31184227 |
| 97 | CSNK1D | 0.29948328 |
| 98 | PRKCI | 0.29807757 |
| 99 | ADRBK1 | 0.27503462 |
| 100 | CSNK2A2 | 0.27489903 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.19097541 |
| 2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.36368225 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.34283649 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.90036348 |
| 5 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.84285331 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.50386807 |
| 7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.27034988 |
| 8 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.22436440 |
| 9 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.11230365 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.07496222 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.06986832 |
| 12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.06523335 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.03336045 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 1.86230191 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.86030750 |
| 16 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.84770192 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.80264842 |
| 18 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.79577401 |
| 19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.76878156 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.75949531 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.73618653 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.61419056 |
| 23 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.54752302 |
| 24 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.54573390 |
| 25 | RNA transport_Homo sapiens_hsa03013 | 1.52100015 |
| 26 | Alzheimers disease_Homo sapiens_hsa05010 | 1.48294766 |
| 27 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.44642435 |
| 28 | DNA replication_Homo sapiens_hsa03030 | 1.38403891 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.37447437 |
| 30 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.35585661 |
| 31 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.28195384 |
| 32 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.25329193 |
| 33 | Spliceosome_Homo sapiens_hsa03040 | 1.22431768 |
| 34 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.21077090 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.17834405 |
| 36 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.17574193 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.17085075 |
| 38 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.15341477 |
| 39 | Base excision repair_Homo sapiens_hsa03410 | 1.13614376 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.12785573 |
| 41 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.09249779 |
| 42 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.05364755 |
| 43 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.04703594 |
| 44 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.04244636 |
| 45 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.99772243 |
| 46 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.99680733 |
| 47 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.98806365 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.98461049 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.90796208 |
| 50 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.90061179 |
| 51 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.89480292 |
| 52 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.84083288 |
| 53 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.83726479 |
| 54 | Circadian rhythm_Homo sapiens_hsa04710 | 0.83652937 |
| 55 | Carbon metabolism_Homo sapiens_hsa01200 | 0.79894937 |
| 56 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.79094280 |
| 57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.74705399 |
| 58 | Nicotine addiction_Homo sapiens_hsa05033 | 0.74101676 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72315020 |
| 60 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.71484700 |
| 61 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.68996952 |
| 62 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.65776134 |
| 63 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.63907641 |
| 64 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63728733 |
| 65 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.61025352 |
| 66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.59079852 |
| 67 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.56986535 |
| 68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.56044070 |
| 69 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.54368694 |
| 70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54034254 |
| 71 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.50759507 |
| 72 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.50292105 |
| 73 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50225556 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.50211412 |
| 75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.50122634 |
| 76 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.48291056 |
| 77 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.48282955 |
| 78 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.47287520 |
| 79 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.46845953 |
| 80 | Taste transduction_Homo sapiens_hsa04742 | 0.46773872 |
| 81 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.46172090 |
| 82 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.45984583 |
| 83 | Cell cycle_Homo sapiens_hsa04110 | 0.45936663 |
| 84 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.45719198 |
| 85 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.45463786 |
| 86 | GABAergic synapse_Homo sapiens_hsa04727 | 0.44422739 |
| 87 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.44283857 |
| 88 | Allograft rejection_Homo sapiens_hsa05330 | 0.42095713 |
| 89 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.41644137 |
| 90 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.39411110 |
| 91 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.37960018 |
| 92 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37280957 |
| 93 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.37043578 |
| 94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.36511656 |
| 95 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.34696644 |
| 96 | Asthma_Homo sapiens_hsa05310 | 0.29176069 |
| 97 | Legionellosis_Homo sapiens_hsa05134 | 0.28851025 |
| 98 | Ribosome_Homo sapiens_hsa03010 | 0.28142893 |
| 99 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.28026259 |
| 100 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.28024976 |

