SUCLG1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* tricarboxylic acid cycle (GO:0006099)6.10822189
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.92797970
3NADH metabolic process (GO:0006734)5.56491157
4ATP synthesis coupled proton transport (GO:0015986)5.44482621
5energy coupled proton transport, down electrochemical gradient (GO:0015985)5.44482621
6lysine catabolic process (GO:0006554)5.41360709
7lysine metabolic process (GO:0006553)5.41360709
8respiratory electron transport chain (GO:0022904)5.18244099
9oxidative phosphorylation (GO:0006119)5.16654584
10mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.16477236
11electron transport chain (GO:0022900)5.05944571
12L-phenylalanine metabolic process (GO:0006558)4.87639006
13erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.87639006
14L-phenylalanine catabolic process (GO:0006559)4.85850618
15erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.85850618
16glyoxylate metabolic process (GO:0046487)4.80150960
17branched-chain amino acid catabolic process (GO:0009083)4.74162049
18fatty acid beta-oxidation (GO:0006635)4.65639719
19aspartate family amino acid catabolic process (GO:0009068)4.53090325
20cellular ketone body metabolic process (GO:0046950)4.46559379
212-oxoglutarate metabolic process (GO:0006103)4.37526904
22short-chain fatty acid metabolic process (GO:0046459)4.32566278
23oxaloacetate metabolic process (GO:0006107)4.32505700
24positive regulation of mitochondrial fission (GO:0090141)4.32143856
25branched-chain amino acid metabolic process (GO:0009081)4.24992071
26fatty acid catabolic process (GO:0009062)4.23275773
27aromatic amino acid family catabolic process (GO:0009074)4.19991447
28carnitine shuttle (GO:0006853)4.19907658
29fatty acid oxidation (GO:0019395)4.19818530
30regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.15868017
31* succinate metabolic process (GO:0006105)4.14487968
32lipid oxidation (GO:0034440)4.13340038
33amino-acid betaine metabolic process (GO:0006577)4.09406217
34acetyl-CoA metabolic process (GO:0006084)4.04248244
35fatty acid transmembrane transport (GO:1902001)4.02305374
36cysteine metabolic process (GO:0006534)3.98308450
37valine metabolic process (GO:0006573)3.94067550
38regulation of acyl-CoA biosynthetic process (GO:0050812)3.93970012
39monocarboxylic acid catabolic process (GO:0072329)3.87707676
40ketone body metabolic process (GO:1902224)3.86269256
41kynurenine metabolic process (GO:0070189)3.83687584
42tricarboxylic acid metabolic process (GO:0072350)3.80883964
43sulfur amino acid catabolic process (GO:0000098)3.80581503
44carnitine metabolic process (GO:0009437)3.79374735
45fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.77507091
46regulation of cofactor metabolic process (GO:0051193)3.72491615
47regulation of coenzyme metabolic process (GO:0051196)3.72491615
48indole-containing compound catabolic process (GO:0042436)3.70360563
49indolalkylamine catabolic process (GO:0046218)3.70360563
50tryptophan catabolic process (GO:0006569)3.70360563
51triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.68388962
52establishment of protein localization to mitochondrial membrane (GO:0090151)3.66900016
53ATP biosynthetic process (GO:0006754)3.64127256
54serine family amino acid catabolic process (GO:0009071)3.60497824
55alpha-amino acid catabolic process (GO:1901606)3.60375954
56regulation of triglyceride catabolic process (GO:0010896)3.54734688
57epoxygenase P450 pathway (GO:0019373)3.54346259
58carboxylic acid catabolic process (GO:0046395)3.54123639
59organic acid catabolic process (GO:0016054)3.54123639
60biotin metabolic process (GO:0006768)3.53425952
61cellular amino acid catabolic process (GO:0009063)3.52667528
62alpha-linolenic acid metabolic process (GO:0036109)3.50235002
63proteasome assembly (GO:0043248)3.49770681
64regulation of sequestering of triglyceride (GO:0010889)3.49403636
65ubiquinone biosynthetic process (GO:0006744)3.45940727
66quinone biosynthetic process (GO:1901663)3.45940727
67carnitine transport (GO:0015879)3.45383601
68amino-acid betaine transport (GO:0015838)3.45383601
69tryptophan metabolic process (GO:0006568)3.44386241
70NAD metabolic process (GO:0019674)3.43587240
71aldehyde catabolic process (GO:0046185)3.42302136
72homocysteine metabolic process (GO:0050667)3.42208137
73bile acid biosynthetic process (GO:0006699)3.41374595
74aerobic respiration (GO:0009060)3.39573286
75ethanol oxidation (GO:0006069)3.38793155
76carnitine transmembrane transport (GO:1902603)3.37771175
77pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.35347110
78regulation of fatty acid oxidation (GO:0046320)3.35084379
79inner mitochondrial membrane organization (GO:0007007)3.33177801
80serine family amino acid biosynthetic process (GO:0009070)3.31720193
81serine family amino acid metabolic process (GO:0009069)3.28548102
82mitochondrial respiratory chain complex I assembly (GO:0032981)3.27971978
83NADH dehydrogenase complex assembly (GO:0010257)3.27971978
84mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.27971978
85hydrogen ion transmembrane transport (GO:1902600)3.25394539
86coenzyme catabolic process (GO:0009109)3.24262527
87aromatic amino acid family metabolic process (GO:0009072)3.22762913
88glycine metabolic process (GO:0006544)3.22234331
89purine nucleoside triphosphate biosynthetic process (GO:0009145)3.19796823
90respiratory chain complex IV assembly (GO:0008535)3.17445793
91peptidyl-arginine omega-N-methylation (GO:0035247)3.15507090
92purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.13672525
93regulation of cholesterol esterification (GO:0010872)3.13357488
94quaternary ammonium group transport (GO:0015697)3.10628668
95* dicarboxylic acid metabolic process (GO:0043648)3.10359536
96protein complex biogenesis (GO:0070271)3.08480109
97drug transmembrane transport (GO:0006855)3.05519991
98regulation of sulfur metabolic process (GO:0042762)3.05320888
99peroxisome fission (GO:0016559)3.04277438
100drug metabolic process (GO:0017144)3.04132143
101small molecule catabolic process (GO:0044282)3.03792755
102ubiquinone metabolic process (GO:0006743)3.02592489
103regulation of guanylate cyclase activity (GO:0031282)3.02285129
104angiotensin maturation (GO:0002003)3.02177486
105* acyl-CoA metabolic process (GO:0006637)3.01945999
106* thioester metabolic process (GO:0035383)3.01945999
107fructose metabolic process (GO:0006000)3.01605499
108base-excision repair, AP site formation (GO:0006285)3.01519910
109regulation of mitochondrial fission (GO:0090140)3.01148160
110mitochondrial respiratory chain complex assembly (GO:0033108)3.01130213
111gluconeogenesis (GO:0006094)3.00561241
112glutamate metabolic process (GO:0006536)2.98817312
113fatty acid homeostasis (GO:0055089)2.97761615
114cellular modified amino acid catabolic process (GO:0042219)2.97666948
115pyrimidine nucleotide catabolic process (GO:0006244)2.96153674
116protein localization to mitochondrion (GO:0070585)2.93997193
117regulation of oxidative phosphorylation (GO:0002082)2.92882993
118regulation of cellular respiration (GO:0043457)2.92323643
119regulation of cellular amino acid metabolic process (GO:0006521)2.92044141
120proton transport (GO:0015992)2.90307419
121mitochondrial transport (GO:0006839)2.87320083
122arginine metabolic process (GO:0006525)2.86000003
123creatine metabolic process (GO:0006600)2.84895365
124hydrogen transport (GO:0006818)2.84587572
125galactose catabolic process (GO:0019388)2.83158457
126protein targeting to mitochondrion (GO:0006626)2.82264906
127hexose biosynthetic process (GO:0019319)2.81735519
128lipid particle organization (GO:0034389)2.80504452
129quinone metabolic process (GO:1901661)2.80436543
130cullin deneddylation (GO:0010388)2.79030179
131ribonucleoside triphosphate biosynthetic process (GO:0009201)2.77784293
132nucleoside diphosphate biosynthetic process (GO:0009133)2.76778680
133purine nucleoside monophosphate biosynthetic process (GO:0009127)2.76179308
134purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.76179308
135activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.74643710
136uronic acid metabolic process (GO:0006063)2.74436107
137glucuronate metabolic process (GO:0019585)2.74436107
138alditol metabolic process (GO:0019400)2.73051439
139L-methionine salvage (GO:0071267)2.71525663
140L-methionine biosynthetic process (GO:0071265)2.71525663
141amino acid salvage (GO:0043102)2.71525663
142cytochrome complex assembly (GO:0017004)2.70184339
143protein K6-linked ubiquitination (GO:0085020)2.68186869
144establishment of protein localization to mitochondrion (GO:0072655)2.68075169
145cellular glucuronidation (GO:0052695)2.65833705
146high-density lipoprotein particle remodeling (GO:0034375)2.61269990
147monosaccharide biosynthetic process (GO:0046364)2.61173643
148negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.60480766
149water-soluble vitamin biosynthetic process (GO:0042364)2.59549057
150regulation of mitochondrial translation (GO:0070129)2.59442922
151glycerol metabolic process (GO:0006071)2.56086044
152bile acid metabolic process (GO:0008206)2.55526439
153nucleoside triphosphate biosynthetic process (GO:0009142)2.54596355
154positive regulation of guanylate cyclase activity (GO:0031284)2.54270664
155vitamin biosynthetic process (GO:0009110)2.54140711
156regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.53983797
157pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.52878266

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse7.47982348
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.10943583
3RXR_22158963_ChIP-Seq_LIVER_Mouse4.81886657
4* PPARA_22158963_ChIP-Seq_LIVER_Mouse4.42666942
5CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.62798573
6EGR1_23403033_ChIP-Seq_LIVER_Mouse3.55824956
7TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.51251831
8* ESRRB_18555785_ChIP-Seq_MESCs_Mouse3.49689814
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.42557326
10* LXR_22158963_ChIP-Seq_LIVER_Mouse3.41802520
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.21355578
12FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.08097460
13* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.01430889
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.94925685
15CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.90515260
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.58094890
17HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.53043559
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.44007291
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.40561959
20EST1_17652178_ChIP-ChIP_JURKAT_Human2.32762591
21PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.31742484
22* SRF_21415370_ChIP-Seq_HL-1_Mouse2.28023043
23* ETS1_20019798_ChIP-Seq_JURKAT_Human2.22939149
24MYC_18555785_ChIP-Seq_MESCs_Mouse1.99441798
25MYC_18358816_ChIP-ChIP_MESCs_Mouse1.96974876
26NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.90893119
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.73535964
28HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.73297769
29YY1_21170310_ChIP-Seq_MESCs_Mouse1.71086674
30* HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.69106109
31ELF1_17652178_ChIP-ChIP_JURKAT_Human1.58916776
32NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.58183438
33BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.50976213
34* ELK1_19687146_ChIP-ChIP_HELA_Human1.49744540
35CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.45488796
36* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.45226664
37DCP1A_22483619_ChIP-Seq_HELA_Human1.44164503
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.40683846
39VDR_22108803_ChIP-Seq_LS180_Human1.40003565
40CDX2_20551321_ChIP-Seq_CACO-2_Human1.38647516
41TTF2_22483619_ChIP-Seq_HELA_Human1.37639844
42STAT3_1855785_ChIP-Seq_MESCs_Mouse1.36673299
43CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.35188657
44* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.31911004
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31665588
46NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.31405172
47PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.31326358
48GABP_19822575_ChIP-Seq_HepG2_Human1.27504923
49TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.25939929
50PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.22498502
51* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.20733336
52* VDR_23849224_ChIP-Seq_CD4+_Human1.19088297
53CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.18995985
54SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.17228563
55* FOXP3_21729870_ChIP-Seq_TREG_Human1.16952943
56CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.15548299
57ZNF263_19887448_ChIP-Seq_K562_Human1.15092115
58HTT_18923047_ChIP-ChIP_STHdh_Human1.14791182
59CLOCK_20551151_ChIP-Seq_293T_Human1.12943785
60FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.12231370
61SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.06361369
62* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.05885856
63ZFX_18555785_ChIP-Seq_MESCs_Mouse1.05577517
64NELFA_20434984_ChIP-Seq_ESCs_Mouse1.05485179
65XRN2_22483619_ChIP-Seq_HELA_Human1.05079912
66GATA1_22025678_ChIP-Seq_K562_Human1.01994786
67MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.00902479
68FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.98567927
69SOX2_22085726_ChIP-Seq_NPCs_Mouse0.95568303
70NCOR_22424771_ChIP-Seq_293T_Human0.95267544
71DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.94087412
72KDM5A_27292631_Chip-Seq_BREAST_Human0.93043287
73RARG_19884340_ChIP-ChIP_MEFs_Mouse0.91701953
74CTCF_18555785_ChIP-Seq_MESCs_Mouse0.90723047
75STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.90201934
76MYC_18940864_ChIP-ChIP_HL60_Human0.89144360
77FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.87522324
78MYC_19079543_ChIP-ChIP_MESCs_Mouse0.85855935
79GATA4_25053715_ChIP-Seq_YYC3_Human0.85466361
80* CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.85379396
81TAF2_19829295_ChIP-Seq_ESCs_Human0.85270554
82ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.84981858
83TBX5_21415370_ChIP-Seq_HL-1_Mouse0.84815555
84RAD21_21589869_ChIP-Seq_MESCs_Mouse0.84313174
85EOMES_21245162_ChIP-Seq_HESCs_Human0.84266694
86GATA4_21415370_ChIP-Seq_HL-1_Mouse0.82142235
87ELK1_22589737_ChIP-Seq_MCF10A_Human0.82103184
88RXRA_24833708_ChIP-Seq_LIVER_Mouse0.82042627
89ERG_20517297_ChIP-Seq_VCAP_Human0.81992974
90P53_21459846_ChIP-Seq_SAOS-2_Human0.81822712
91CTCF_26484167_Chip-Seq_Bcells_Mouse0.80810326
92PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.80638197
93SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.80494214
94TP53_22573176_ChIP-Seq_HFKS_Human0.80195479
95AR_20517297_ChIP-Seq_VCAP_Human0.79997657
96* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.79635020
97MYC_19829295_ChIP-Seq_ESCs_Human0.78809608
98YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.77982622
99* HNF4A_19822575_ChIP-Seq_HepG2_Human0.77708154
100POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.77674718
101MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.77475582
102TET1_21451524_ChIP-Seq_MESCs_Mouse0.77139966
103PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.76978125
104ERA_21632823_ChIP-Seq_H3396_Human0.76969420
105MYCN_18555785_ChIP-Seq_MESCs_Mouse0.75419157
106* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.75179624
107YY1_22570637_ChIP-Seq_MALME-3M_Human0.74527394
108POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.74415672
109OCT4_18692474_ChIP-Seq_MEFs_Mouse0.73825140
110PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.73496318
111NANOG_18555785_ChIP-Seq_MESCs_Mouse0.73181207
112ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.72183139
113AR_21909140_ChIP-Seq_LNCAP_Human0.72120469
114BCL6_27268052_Chip-Seq_Bcells_Human0.71580774
115BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.71393511
116SRY_22984422_ChIP-ChIP_TESTIS_Rat0.70843581
117RARA_24833708_ChIP-Seq_LIVER_Mouse0.70186377
118POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.69726664
119AUTS2_25519132_ChIP-Seq_293T-REX_Human0.69221862
120TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.69060393
121PADI4_21655091_ChIP-ChIP_MCF-7_Human0.67658101
122HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.67638239
123SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.67305479
124SOX2_18692474_ChIP-Seq_MEFs_Mouse0.67293494
125* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.66934504
126SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.66117523
127KAP1_22055183_ChIP-Seq_ESCs_Mouse0.65440953
128NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.64567929

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis5.44325774
2MP0002139_abnormal_hepatobiliary_system5.32785485
3MP0003806_abnormal_nucleotide_metabolis4.65465917
4MP0005085_abnormal_gallbladder_physiolo4.45152591
5MP0005365_abnormal_bile_salt4.19562219
6MP0002837_dystrophic_cardiac_calcinosis4.09959571
7MP0003646_muscle_fatigue3.79689258
8MP0008875_abnormal_xenobiotic_pharmacok3.45082292
9MP0006036_abnormal_mitochondrial_physio3.30739366
10MP0005332_abnormal_amino_acid3.08491706
11MP0003195_calcinosis2.82391330
12MP0000566_synostosis2.51666541
13MP0010329_abnormal_lipoprotein_level2.47741988
14MP0004084_abnormal_cardiac_muscle2.31331760
15MP0003252_abnormal_bile_duct2.26606376
16MP0004215_abnormal_myocardial_fiber2.23752230
17MP0006035_abnormal_mitochondrial_morpho2.20986888
18MP0009840_abnormal_foam_cell2.17567058
19MP0005670_abnormal_white_adipose2.15899587
20MP0004036_abnormal_muscle_relaxation2.14757795
21MP0000751_myopathy2.14710307
22MP0005330_cardiomyopathy2.14673097
23MP0004130_abnormal_muscle_cell2.12955191
24MP0005083_abnormal_biliary_tract2.09743098
25MP0001666_abnormal_nutrient_absorption2.04417967
26MP0009379_abnormal_foot_pigmentation1.97497930
27MP0001764_abnormal_homeostasis1.94826917
28MP0000749_muscle_degeneration1.93873269
29MP0000372_irregular_coat_pigmentation1.93267992
30MP0003186_abnormal_redox_activity1.92680720
31MP0004043_abnormal_pH_regulation1.87803517
32MP0005319_abnormal_enzyme/_coenzyme1.84745286
33MP0002118_abnormal_lipid_homeostasis1.80620315
34MP0005408_hypopigmentation1.73616871
35MP0002638_abnormal_pupillary_reflex1.72349246
36MP0005584_abnormal_enzyme/coenzyme_acti1.71506200
37MP0004019_abnormal_vitamin_homeostasis1.70681611
38MP0009643_abnormal_urine_homeostasis1.68463308
39MP0005451_abnormal_body_composition1.62883414
40MP0005266_abnormal_metabolism1.60433676
41MP0000609_abnormal_liver_physiology1.48060673
42MP0002269_muscular_atrophy1.44434008
43MP0009697_abnormal_copulation1.43332767
44MP0005666_abnormal_adipose_tissue1.40600070
45MP0002972_abnormal_cardiac_muscle1.36946297
46MP0005636_abnormal_mineral_homeostasis1.35191338
47MP0009780_abnormal_chondrocyte_physiolo1.34389135
48MP0005535_abnormal_body_temperature1.32494812
49MP0003221_abnormal_cardiomyocyte_apopto1.31503889
50MP0005385_cardiovascular_system_phenoty1.28965920
51MP0001544_abnormal_cardiovascular_syste1.28965920
52MP0005620_abnormal_muscle_contractility1.28915103
53MP0002971_abnormal_brown_adipose1.27619421
54MP0003191_abnormal_cellular_cholesterol1.26827820
55MP0004087_abnormal_muscle_fiber1.25918702
56MP0008775_abnormal_heart_ventricle1.18741093
57MP0002876_abnormal_thyroid_physiology1.18700671
58MP0006138_congestive_heart_failure1.18179936
59MP0003137_abnormal_impulse_conducting1.18095962
60MP0002332_abnormal_exercise_endurance1.17727902
61MP0000747_muscle_weakness1.15412089
62MP0003567_abnormal_fetal_cardiomyocyte1.13282458
63MP0009046_muscle_twitch1.12950371
64MP0005376_homeostasis/metabolism_phenot1.12925284
65MP0005084_abnormal_gallbladder_morpholo1.11916975
66MP0002822_catalepsy1.11271417
67MP0005058_abnormal_lysosome_morphology1.11148063
68MP0002078_abnormal_glucose_homeostasis1.10648873
69MP0001756_abnormal_urination1.08499052
70MP0002938_white_spotting1.07102797
71MP0003183_abnormal_peptide_metabolism1.05698248
72MP0004147_increased_porphyrin_level1.02773827
73MP0000750_abnormal_muscle_regeneration1.00041390
74MP0002106_abnormal_muscle_physiology0.99614462
75MP0004484_altered_response_of0.98863227
76MP0002138_abnormal_hepatobiliary_system0.95744059
77MP0000230_abnormal_systemic_arterial0.95681457
78MP0001485_abnormal_pinna_reflex0.91145833
79MP0005551_abnormal_eye_electrophysiolog0.90351656
80MP0010630_abnormal_cardiac_muscle0.87606886
81MP0003656_abnormal_erythrocyte_physiolo0.87282632
82MP0001661_extended_life_span0.85052946
83MP0001727_abnormal_embryo_implantation0.81236177
84MP0001664_abnormal_digestion0.80572317
85MP0009642_abnormal_blood_homeostasis0.80328937
86MP0005645_abnormal_hypothalamus_physiol0.80117949
87MP0003868_abnormal_feces_composition0.79415491
88MP0005448_abnormal_energy_balance0.79411063
89MP0004145_abnormal_muscle_electrophysio0.78532939
90MP0003879_abnormal_hair_cell0.78340372
91MP0000598_abnormal_liver_morphology0.78332582
92MP0001765_abnormal_ion_homeostasis0.78273714
93MP0004085_abnormal_heartbeat0.76774053
94MP0004233_abnormal_muscle_weight0.76647068
95MP0005334_abnormal_fat_pad0.75212282
96MP0005369_muscle_phenotype0.75195881
97MP0005379_endocrine/exocrine_gland_phen0.73121105
98MP0008260_abnormal_autophagy0.72862137
99MP0008872_abnormal_physiological_respon0.71435700
100MP0001984_abnormal_olfaction0.71102786
101MP0000759_abnormal_skeletal_muscle0.71094219
102MP0000013_abnormal_adipose_tissue0.70866941
103MP0001529_abnormal_vocalization0.70340057
104MP0000538_abnormal_urinary_bladder0.69751973
105MP0002909_abnormal_adrenal_gland0.68797132
106MP0005165_increased_susceptibility_to0.68790809
107MP0002127_abnormal_cardiovascular_syste0.68017965
108MP0002272_abnormal_nervous_system0.67502261
109MP0005375_adipose_tissue_phenotype0.66489503
110MP0003122_maternal_imprinting0.66175323
111MP0004270_analgesia0.65894343
112MP0003953_abnormal_hormone_level0.64885991
113MP0004924_abnormal_behavior0.63576874
114MP0005386_behavior/neurological_phenoty0.63576874
115MP0001905_abnormal_dopamine_level0.63559158
116MP0008877_abnormal_DNA_methylation0.63005911
117MP0002970_abnormal_white_adipose0.61938707
118MP0003011_delayed_dark_adaptation0.59677224
119MP0008469_abnormal_protein_level0.59160027
120MP0005647_abnormal_sex_gland0.58277705
121MP0003329_amyloid_beta_deposits0.58154418
122MP0003959_abnormal_lean_body0.57719987
123MP0000358_abnormal_cell_content/0.57317812
124MP0001853_heart_inflammation0.56111028
125MP0003718_maternal_effect0.55902431
126MP0005452_abnormal_adipose_tissue0.55751925
127MP0000343_altered_response_to0.53451057
128MP0009763_increased_sensitivity_to0.52191468
129MP0010368_abnormal_lymphatic_system0.51032316

Predicted human phenotypes

RankGene SetZ-score
1Hepatic necrosis (HP:0002605)5.08178854
2Acute encephalopathy (HP:0006846)4.92793765
3Acute necrotizing encephalopathy (HP:0006965)4.91804878
4Abnormal mitochondria in muscle tissue (HP:0008316)4.87289111
5Cerebral edema (HP:0002181)4.61339337
6Abnormality of fatty-acid metabolism (HP:0004359)4.54358328
7Hyperglycinuria (HP:0003108)4.49195759
8Hepatocellular necrosis (HP:0001404)4.46752152
9Hypoglycemic coma (HP:0001325)4.43001137
10Mitochondrial inheritance (HP:0001427)4.26236222
11* Dicarboxylic aciduria (HP:0003215)4.22392854
12* Abnormality of dicarboxylic acid metabolism (HP:0010995)4.22392854
13Hyperammonemia (HP:0001987)4.14354507
14Increased CSF lactate (HP:0002490)4.11060433
15Abnormality of glycine metabolism (HP:0010895)4.03622329
16Abnormality of serine family amino acid metabolism (HP:0010894)4.03622329
17Progressive macrocephaly (HP:0004481)4.02707095
18Generalized aminoaciduria (HP:0002909)3.96717211
19Ketosis (HP:0001946)3.93651716
20Myoglobinuria (HP:0002913)3.92378801
21Abnormality of aromatic amino acid family metabolism (HP:0004338)3.86778895
22Ketoacidosis (HP:0001993)3.77611096
23* Lactic acidosis (HP:0003128)3.73470944
24Abnormality of glycolysis (HP:0004366)3.73178195
25Increased serum pyruvate (HP:0003542)3.73178195
26Hyperglycinemia (HP:0002154)3.71629175
27Lethargy (HP:0001254)3.69764430
28Increased muscle lipid content (HP:0009058)3.67982979
29Rhabdomyolysis (HP:0003201)3.56298633
30Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.46582893
31Hypobetalipoproteinemia (HP:0003563)3.28667212
32Increased intramyocellular lipid droplets (HP:0012240)3.27269921
33Proximal tubulopathy (HP:0000114)3.27185771
34Decreased activity of mitochondrial respiratory chain (HP:0008972)3.18825049
35Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.18825049
36Palpitations (HP:0001962)3.18792580
37Intrahepatic cholestasis (HP:0001406)3.17771907
38Lipid accumulation in hepatocytes (HP:0006561)3.16519260
39Metabolic acidosis (HP:0001942)3.10861039
40Increased serum lactate (HP:0002151)3.08648960
41* Respiratory failure (HP:0002878)3.02112883
42Xanthomatosis (HP:0000991)3.00634131
43Exercise intolerance (HP:0003546)3.00533970
44Muscle fiber inclusion bodies (HP:0100299)2.93049834
45Abnormality of urine glucose concentration (HP:0011016)2.92513745
46Glycosuria (HP:0003076)2.92513745
47Vomiting (HP:0002013)2.92223176
48Abnormality of serum amino acid levels (HP:0003112)2.90137463
49Exercise-induced myalgia (HP:0003738)2.88270561
50Gout (HP:0001997)2.87616087
51Abnormality of monocarboxylic acid metabolism (HP:0010996)2.87529180
52Nemaline bodies (HP:0003798)2.83297221
53Nausea (HP:0002018)2.83286713
54Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.80337360
55Hyperlipoproteinemia (HP:0010980)2.76408246
56Ragged-red muscle fibers (HP:0003200)2.69534984
57Abnormality of aspartate family amino acid metabolism (HP:0010899)2.68795314
58Hypolipoproteinemia (HP:0010981)2.67336679
59CNS demyelination (HP:0007305)2.66666112
60Abnormality of glutamine family amino acid metabolism (HP:0010902)2.64522228
61Abnormality of alanine metabolism (HP:0010916)2.63188828
62Hyperalaninemia (HP:0003348)2.63188828
63Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.63188828
64Increased hepatocellular lipid droplets (HP:0006565)2.62517905
65Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.62073102
66Exercise-induced muscle cramps (HP:0003710)2.57226779
67Sudden death (HP:0001699)2.56914123
68Pheochromocytoma (HP:0002666)2.56067259
69Abnormality of proline metabolism (HP:0010907)2.56024827
70Hydroxyprolinuria (HP:0003080)2.56024827
71Deep venous thrombosis (HP:0002625)2.52532083
72Neuroendocrine neoplasm (HP:0100634)2.49177800
73Renal cortical cysts (HP:0000803)2.48115180
74Abnormality of vitamin B metabolism (HP:0004340)2.47771358
75Conjunctival hamartoma (HP:0100780)2.46593159
76Abnormality of the vitamin B12 metabolism (HP:0004341)2.46544306
77Prolonged partial thromboplastin time (HP:0003645)2.45909079
78Hyperphosphaturia (HP:0003109)2.39494467
79Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.38194423
80Hypoalphalipoproteinemia (HP:0003233)2.36814745
81Leukodystrophy (HP:0002415)2.33423553
82Delayed CNS myelination (HP:0002188)2.32298572
83Neoplasm of head and neck (HP:0012288)2.29727384
84Esophageal neoplasm (HP:0100751)2.29727384
85* Methylmalonic aciduria (HP:0012120)2.28802457
86Hyperuricemia (HP:0002149)2.26719554
87Increased purine levels (HP:0004368)2.26719554
88Abnormality of methionine metabolism (HP:0010901)2.25618747
89Calf muscle hypertrophy (HP:0008981)2.24511189
90Abnormality of purine metabolism (HP:0004352)2.23032667
91Optic disc pallor (HP:0000543)2.22339435
92Abnormality of sulfur amino acid metabolism (HP:0004339)2.21561594
93Renal Fanconi syndrome (HP:0001994)2.21216643
94Ventricular tachycardia (HP:0004756)2.17563946
95Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.13924964
96Muscle hypertrophy of the lower extremities (HP:0008968)2.13025378
97Macrocytic anemia (HP:0001972)2.11810331
983-Methylglutaconic aciduria (HP:0003535)2.11375959
99Abnormality of nucleobase metabolism (HP:0010932)2.08469332
100Steatorrhea (HP:0002570)2.08441846
101Hyperbilirubinemia (HP:0002904)2.08144360
102Emotional lability (HP:0000712)2.08039755
103Neoplasm of the adrenal gland (HP:0100631)2.07196013
104Abnormality of vitamin metabolism (HP:0100508)2.06568263
105Abnormality of magnesium homeostasis (HP:0004921)2.05553517
106Methylmalonic acidemia (HP:0002912)2.03896826
107Absent rod-and cone-mediated responses on ERG (HP:0007688)2.00042946
108Type I transferrin isoform profile (HP:0003642)1.99485580
109Cerebral palsy (HP:0100021)1.98276325
110Muscle stiffness (HP:0003552)1.97894865
111Fat malabsorption (HP:0002630)1.97653343
112Confusion (HP:0001289)1.97222866
113Dilated cardiomyopathy (HP:0001644)1.95756020
114Cholelithiasis (HP:0001081)1.95199530
115Late onset (HP:0003584)1.94141301
116Hyperinsulinemic hypoglycemia (HP:0000825)1.93447023
117Alkalosis (HP:0001948)1.92444519
118Megaloblastic anemia (HP:0001889)1.92427632
119Brushfield spots (HP:0001088)1.91136964
120Abnormal urine phosphate concentration (HP:0012599)1.86231887
121Bundle branch block (HP:0011710)1.81391535

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.20655018
2PDK44.48003997
3PDK34.48003997
4VRK23.35790170
5MYLK3.27311732
6NEK13.08190689
7OBSCN2.95572147
8STK162.81775566
9PDK22.64439602
10NME12.33444061
11CDK82.17619894
12LMTK22.12953989
13PINK12.09770417
14EIF2AK12.08544328
15STK38L1.97390915
16CSNK1G31.95168000
17NME21.93724227
18LIMK11.83300952
19PHKG11.80944350
20PHKG21.80944350
21TTN1.75106802
22WNK41.69625402
23BUB11.69618091
24TIE11.65799126
25MAP4K21.64581895
26CDK191.64359548
27CSNK1G21.63979176
28CSNK1G11.55355704
29MAP3K121.52115274
30CSNK1A1L1.51466743
31KDR1.44842297
32PIK3CA1.43778740
33WNK31.41927474
34TRIB31.33696839
35TESK11.31618649
36MUSK1.30708920
37FLT31.25828339
38ARAF1.25178691
39PKN21.20449129
40SIK11.20275365
41DYRK1B1.18256186
42WEE11.18073435
43ACVR1B1.15263849
44MAP2K31.14474423
45PIK3CG1.14026956
46SCYL21.12767552
47STK241.12618666
48MST1R1.11541354
49MAP2K41.09946232
50NUAK11.08988674
51EIF2AK31.02293800
52TSSK61.02239033
53ILK0.99816678
54GRK50.97251118
55MAP3K110.96955750
56OXSR10.96636390
57BCR0.94628301
58ABL20.91502337
59ERN10.90057842
60DYRK20.89079894
61MAP3K70.80778741
62GRK10.78933995
63CAMK2G0.78859873
64CASK0.78699268
65MAP3K30.77363617
66BRAF0.76828395
67INSRR0.75504104
68MAPK110.72115735
69CAMKK20.71725571
70MARK10.70895176
71MST40.70445125
72MAPK120.69592999
73TESK20.69149275
74GRK70.67592650
75MAP2K60.67180763
76NEK90.66962413
77LRRK20.66192101
78CAMK2D0.65874430
79PRKAA20.64992386
80ZAK0.64740840
81ERBB30.61792330
82DAPK30.59517849
83GRK60.59379846
84PRKAA10.57376576
85MOS0.56790865
86CSNK1A10.56118144
87FGFR40.55286695
88RPS6KA50.54432495
89STK40.54391401
90MAPKAPK50.53631264
91BRSK20.53273154
92IRAK30.52849696
93MINK10.51898960
94PRKACG0.51895350
95CCNB10.51249948
96ERBB40.50502446
97VRK10.50271481
98EIF2AK20.49514361
99DMPK0.49468424
100PRKCE0.45378199
101MAP2K10.44946563
102PIM20.44549903
103TLK10.44367525
104MAP3K50.44346994
105MAPKAPK30.44084165
106PRKACA0.44040672
107PLK10.39609251
108DYRK30.39100507
109SRPK10.38708579
110PRKACB0.37786049
111PDPK10.37733735
112MAP2K70.36748620
113AURKB0.36711810
114CSNK2A10.36449027
115EPHB20.34247872
116STK390.33176384
117PRKCG0.32990557
118DAPK10.32903629
119TTK0.32761225
120AKT20.31131726
121MAPK40.31046023
122MAP2K20.27652950
123TEC0.27569417
124CAMK2A0.27377433
125AURKA0.26591800
126PLK40.25440965
127CSNK2A20.24810600
128PRKCA0.21679163
129PBK0.21623470
130CDK40.20815132
131PRKG20.20326376
132AKT30.19988017
133ADRBK20.19680297
134PDK10.18826919
135PAK30.17792846
136PRKCI0.17576669
137RAF10.17163592
138MAP3K40.16899421
139CAMK2B0.16876710

Predicted pathways (KEGG)

RankGene SetZ-score
1* Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.02566462
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.31128233
3* Propanoate metabolism_Homo sapiens_hsa006403.17244103
4Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006303.07608390
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.02773807
6Fatty acid degradation_Homo sapiens_hsa000712.96575862
7Oxidative phosphorylation_Homo sapiens_hsa001902.89341104
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.69949668
9Parkinsons disease_Homo sapiens_hsa050122.61471081
10Pyruvate metabolism_Homo sapiens_hsa006202.48581859
11* Carbon metabolism_Homo sapiens_hsa012002.35060037
12Butanoate metabolism_Homo sapiens_hsa006502.30783746
13Fatty acid metabolism_Homo sapiens_hsa012122.29619857
14Primary bile acid biosynthesis_Homo sapiens_hsa001202.20029484
15Tryptophan metabolism_Homo sapiens_hsa003801.97432681
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.94754319
17Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.94357709
18Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.94133894
19Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.91840077
20Peroxisome_Homo sapiens_hsa041461.90882472
21Fatty acid elongation_Homo sapiens_hsa000621.87632990
22Alzheimers disease_Homo sapiens_hsa050101.76774920
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.76201198
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.70163889
25Huntingtons disease_Homo sapiens_hsa050161.69567923
26Arginine biosynthesis_Homo sapiens_hsa002201.68330598
27PPAR signaling pathway_Homo sapiens_hsa033201.63948799
28Biosynthesis of amino acids_Homo sapiens_hsa012301.62861087
29beta-Alanine metabolism_Homo sapiens_hsa004101.62595444
30Sulfur metabolism_Homo sapiens_hsa009201.55750410
31Pentose and glucuronate interconversions_Homo sapiens_hsa000401.52476934
32Proteasome_Homo sapiens_hsa030501.48450901
33Cysteine and methionine metabolism_Homo sapiens_hsa002701.41162203
34Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.40835122
35Cardiac muscle contraction_Homo sapiens_hsa042601.38395845
36Nitrogen metabolism_Homo sapiens_hsa009101.34368833
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.29493913
38Drug metabolism - other enzymes_Homo sapiens_hsa009831.25801463
39Phenylalanine metabolism_Homo sapiens_hsa003601.23785074
40Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.19773591
41Starch and sucrose metabolism_Homo sapiens_hsa005001.13542766
42Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.13395587
43Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.12064955
44Histidine metabolism_Homo sapiens_hsa003401.09061222
45Tyrosine metabolism_Homo sapiens_hsa003501.08289604
46Chemical carcinogenesis_Homo sapiens_hsa052041.07710558
47Folate biosynthesis_Homo sapiens_hsa007901.07101124
48Pentose phosphate pathway_Homo sapiens_hsa000301.04038148
49Selenocompound metabolism_Homo sapiens_hsa004501.03327046
50Arginine and proline metabolism_Homo sapiens_hsa003301.01594121
51Fat digestion and absorption_Homo sapiens_hsa049751.01138673
52Cyanoamino acid metabolism_Homo sapiens_hsa004600.98963870
53Mismatch repair_Homo sapiens_hsa034300.98479711
54Fructose and mannose metabolism_Homo sapiens_hsa000510.98055810
55Glutathione metabolism_Homo sapiens_hsa004800.92935578
56Renin-angiotensin system_Homo sapiens_hsa046140.92711571
57Sulfur relay system_Homo sapiens_hsa041220.88974671
58* Metabolic pathways_Homo sapiens_hsa011000.86617595
59Steroid hormone biosynthesis_Homo sapiens_hsa001400.85973726
60Mineral absorption_Homo sapiens_hsa049780.85688785
61Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.85272494
62Complement and coagulation cascades_Homo sapiens_hsa046100.84170833
63Retinol metabolism_Homo sapiens_hsa008300.83981745
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81234475
65Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.79006813
66Galactose metabolism_Homo sapiens_hsa000520.76193765
67Bile secretion_Homo sapiens_hsa049760.74871360
68Base excision repair_Homo sapiens_hsa034100.74321559
69Caffeine metabolism_Homo sapiens_hsa002320.73652768
70Glycerolipid metabolism_Homo sapiens_hsa005610.71516673
71Vitamin B6 metabolism_Homo sapiens_hsa007500.66440353
72Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.65980028
73Ribosome_Homo sapiens_hsa030100.63637135
74Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62316463
75Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.61006688
76Nucleotide excision repair_Homo sapiens_hsa034200.57965893
77Vitamin digestion and absorption_Homo sapiens_hsa049770.52709462
78Homologous recombination_Homo sapiens_hsa034400.51872159
79Fatty acid biosynthesis_Homo sapiens_hsa000610.51786917
80Maturity onset diabetes of the young_Homo sapiens_hsa049500.50154037
81Protein export_Homo sapiens_hsa030600.48744071
82Pyrimidine metabolism_Homo sapiens_hsa002400.48463268
83Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.43294572
84One carbon pool by folate_Homo sapiens_hsa006700.42321564
85Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.41332497
86Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.39977885
87ABC transporters_Homo sapiens_hsa020100.37822575
88RNA degradation_Homo sapiens_hsa030180.36685179
89Glucagon signaling pathway_Homo sapiens_hsa049220.34148053
90Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.29161670
91RNA polymerase_Homo sapiens_hsa030200.27968237
92Collecting duct acid secretion_Homo sapiens_hsa049660.26523927
93Adipocytokine signaling pathway_Homo sapiens_hsa049200.26047720
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.24462091
95Purine metabolism_Homo sapiens_hsa002300.23720287
96Steroid biosynthesis_Homo sapiens_hsa001000.23327817
97Lysine degradation_Homo sapiens_hsa003100.23318596
98alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.22954014
99Linoleic acid metabolism_Homo sapiens_hsa005910.20480224
100Regulation of autophagy_Homo sapiens_hsa041400.19574982
101Glycerophospholipid metabolism_Homo sapiens_hsa005640.17252539
102Fanconi anemia pathway_Homo sapiens_hsa034600.17112117
103Ether lipid metabolism_Homo sapiens_hsa005650.16468170
104Protein digestion and absorption_Homo sapiens_hsa049740.16162470
105Basal transcription factors_Homo sapiens_hsa030220.13951658
106Arachidonic acid metabolism_Homo sapiens_hsa005900.12252036
107Staphylococcus aureus infection_Homo sapiens_hsa051500.12110780
108Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.10453901
109Insulin resistance_Homo sapiens_hsa049310.10183751
110AMPK signaling pathway_Homo sapiens_hsa041520.09399725
111DNA replication_Homo sapiens_hsa030300.05444349
112Dilated cardiomyopathy_Homo sapiens_hsa054140.03471523
113Insulin signaling pathway_Homo sapiens_hsa049100.03147599
114Vibrio cholerae infection_Homo sapiens_hsa05110-0.0031618

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