SUCO

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of cilium movement (GO:0003352)7.63682696
2attachment of spindle microtubules to kinetochore (GO:0008608)5.81123434
3positive regulation of dendritic spine morphogenesis (GO:0061003)5.55332463
4otic vesicle formation (GO:0030916)5.30966631
5regulation of pigment cell differentiation (GO:0050932)4.89712243
6short-term memory (GO:0007614)4.78793612
7cytoplasmic mRNA processing body assembly (GO:0033962)4.35231054
8regulation of microtubule-based movement (GO:0060632)4.25479770
9positive regulation of developmental pigmentation (GO:0048087)4.25051661
10piRNA metabolic process (GO:0034587)4.22211319
11cilium or flagellum-dependent cell motility (GO:0001539)4.16619170
12nuclear pore complex assembly (GO:0051292)4.12614531
13mitotic sister chromatid cohesion (GO:0007064)4.12344583
14positive regulation of DNA-templated transcription, initiation (GO:2000144)4.11039336
15synaptic vesicle endocytosis (GO:0048488)4.08421368
16establishment of mitotic spindle orientation (GO:0000132)4.06740675
17acrosome assembly (GO:0001675)4.06042985
18establishment of spindle orientation (GO:0051294)3.94699680
19fusion of sperm to egg plasma membrane (GO:0007342)3.90891610
20microtubule anchoring (GO:0034453)3.89891118
21regulation of growth hormone secretion (GO:0060123)3.84124191
22monoubiquitinated protein deubiquitination (GO:0035520)3.71528348
23multicellular organism reproduction (GO:0032504)3.67263666
24establishment of mitotic spindle localization (GO:0040001)3.64617635
25establishment of spindle localization (GO:0051293)3.62008655
26male meiosis (GO:0007140)3.49355319
27regulation of protein polyubiquitination (GO:1902914)3.45985966
28mitotic spindle organization (GO:0007052)3.43752697
29sister chromatid segregation (GO:0000819)3.39244190
30negative regulation of axon guidance (GO:1902668)3.38778127
31negative regulation of keratinocyte proliferation (GO:0010839)3.25748947
32protein targeting to Golgi (GO:0000042)3.22915318
33histone H3-K36 demethylation (GO:0070544)3.21437470
34retrograde transport, vesicle recycling within Golgi (GO:0000301)3.20267800
35positive regulation of growth hormone secretion (GO:0060124)3.20049094
36mitotic sister chromatid segregation (GO:0000070)3.18212041
37establishment of protein localization to Golgi (GO:0072600)3.14906328
38nuclear pore organization (GO:0006999)3.12044282
39mitochondrial DNA replication (GO:0006264)3.10612939
40paraxial mesoderm development (GO:0048339)3.07294612
41reproduction (GO:0000003)3.03289646
42bundle of His cell to Purkinje myocyte communication (GO:0086069)3.02624236
43COPI coating of Golgi vesicle (GO:0048205)3.02020899
44Golgi transport vesicle coating (GO:0048200)3.02020899
45histone H3-K9 demethylation (GO:0033169)2.99330328
46sperm motility (GO:0030317)2.99318764
47growth hormone receptor signaling pathway (GO:0060396)2.98712234
48pore complex assembly (GO:0046931)2.98490176
49sperm-egg recognition (GO:0035036)2.97128403
50embryonic retina morphogenesis in camera-type eye (GO:0060059)2.94912443
51genitalia morphogenesis (GO:0035112)2.94199059
52cell wall macromolecule catabolic process (GO:0016998)2.94136149
53cell wall macromolecule metabolic process (GO:0044036)2.94136149
54regulation of axon guidance (GO:1902667)2.94025217
55epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.90800404
56gene silencing by RNA (GO:0031047)2.88355120
57type B pancreatic cell development (GO:0003323)2.87964301
58regulation of Rac protein signal transduction (GO:0035020)2.85860082
59regulation of cardioblast differentiation (GO:0051890)2.85625572
60histone lysine demethylation (GO:0070076)2.85069834
61interkinetic nuclear migration (GO:0022027)2.84366709
62regulation of DNA-templated transcription, initiation (GO:2000142)2.83446185
63oocyte development (GO:0048599)2.82465135
64axonemal dynein complex assembly (GO:0070286)2.82408472
65regulation of RNA export from nucleus (GO:0046831)2.81442186
66cerebral cortex radially oriented cell migration (GO:0021799)2.79946902
67spermatid development (GO:0007286)2.78366951
68cell-cell recognition (GO:0009988)2.77581119
69histone demethylation (GO:0016577)2.77552503
70positive regulation of dendrite morphogenesis (GO:0050775)2.77456216
71binding of sperm to zona pellucida (GO:0007339)2.72558183
72macroautophagy (GO:0016236)2.71164486
73DNA methylation involved in gamete generation (GO:0043046)2.69655091
74synaptonemal complex organization (GO:0070193)2.69260029
75synaptonemal complex assembly (GO:0007130)2.67080360
76plasma membrane fusion (GO:0045026)2.64889342
77regulation of developmental pigmentation (GO:0048070)2.64868801
78positive regulation of macroautophagy (GO:0016239)2.63742068
79negative regulation of axon extension involved in axon guidance (GO:0048843)2.63294635
80sister chromatid cohesion (GO:0007062)2.63030562
81negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.62677627
82seminiferous tubule development (GO:0072520)2.60402423
83cellular response to growth hormone stimulus (GO:0071378)2.59040324
84regulation of mRNA catabolic process (GO:0061013)2.58824486
85negative regulation of inclusion body assembly (GO:0090084)2.58286377
86gastrulation with mouth forming second (GO:0001702)2.57583556
87positive regulation of hormone biosynthetic process (GO:0046886)2.55079077
88branching involved in prostate gland morphogenesis (GO:0060442)2.54908075
89limb bud formation (GO:0060174)2.54249347
90regulation of transforming growth factor beta2 production (GO:0032909)2.54150901
91regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.53870539
92positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.53870539
93polyol catabolic process (GO:0046174)2.53328836
94positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.53204430
95regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.53204430
96intestinal epithelial cell development (GO:0060576)2.53081842
97endosome to melanosome transport (GO:0035646)2.52163653
98endosome to pigment granule transport (GO:0043485)2.52163653
99regulation of nucleobase-containing compound transport (GO:0032239)2.51683886
100negative regulation of DNA repair (GO:0045738)2.51567371
101positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.50895057
102positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.50895057
103positive regulation of mitotic sister chromatid separation (GO:1901970)2.50895057
104regulation of interleukin-12 biosynthetic process (GO:0045075)2.50474922
105regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.50406024
106epithelial cilium movement (GO:0003351)2.49566484
107chondrocyte development (GO:0002063)2.48387932
108centriole replication (GO:0007099)2.46943590
109replicative senescence (GO:0090399)2.46555273
110meiotic cell cycle (GO:0051321)2.46553284
111positive regulation of mRNA catabolic process (GO:0061014)2.46103194
112histone H2A monoubiquitination (GO:0035518)2.45535308
113positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)2.45217790
114regulation of non-canonical Wnt signaling pathway (GO:2000050)2.45125576
115glycoprotein catabolic process (GO:0006516)2.44944306
116glandular epithelial cell development (GO:0002068)2.44394201
117mitochondrial DNA metabolic process (GO:0032042)2.43883591
118cerebral cortex cell migration (GO:0021795)2.43334212
119phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.43273318
120regulation of axon extension involved in axon guidance (GO:0048841)2.42768068
121histone H3-K9 methylation (GO:0051567)2.41151918
122protein dealkylation (GO:0008214)2.40524119
123protein demethylation (GO:0006482)2.40524119
124regulation of histone H3-K9 methylation (GO:0051570)2.37950538
125embryonic camera-type eye morphogenesis (GO:0048596)2.37749239
126regulation of centriole replication (GO:0046599)2.37198509
127early endosome to late endosome transport (GO:0045022)2.34752206
128protein deubiquitination (GO:0016579)2.34160978
129non-canonical Wnt signaling pathway (GO:0035567)2.32697045
130positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043)2.32334615
131response to UV-C (GO:0010225)2.30504052
132columnar/cuboidal epithelial cell development (GO:0002066)2.29231418
133pre-miRNA processing (GO:0031054)2.28923878
134histone mRNA catabolic process (GO:0071044)2.28565226
135microtubule depolymerization (GO:0007019)2.27572184
136negative regulation of histone methylation (GO:0031061)2.27524097
137regulation of meiosis I (GO:0060631)2.26322617
138glomerulus development (GO:0032835)2.26212728
139ganglion development (GO:0061548)2.25629827
140protein localization to cell surface (GO:0034394)2.24888273
141single fertilization (GO:0007338)2.24491417
142dorsal/ventral axis specification (GO:0009950)2.23829554
143fertilization (GO:0009566)2.23805586
144deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.23619718
145centrosome localization (GO:0051642)2.23478423
146prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.23476254
147ER overload response (GO:0006983)2.23324529
148positive regulation of gamma-delta T cell activation (GO:0046645)2.23206878
149regulation of keratinocyte proliferation (GO:0010837)2.23128718
150histone H3-K9 modification (GO:0061647)2.23095125
151morphogenesis of an epithelial sheet (GO:0002011)2.22984934
152COPII vesicle coating (GO:0048208)2.22935051
153negative regulation of cell fate specification (GO:0009996)2.22433370
154regulation of fibroblast apoptotic process (GO:2000269)2.20718661
155negative regulation of fibroblast apoptotic process (GO:2000270)2.20138342
156hindbrain development (GO:0030902)2.19038905
157apical protein localization (GO:0045176)2.18376189
158definitive hemopoiesis (GO:0060216)2.16601683
159mitotic chromosome condensation (GO:0007076)2.15743859
160negative regulation of glycogen biosynthetic process (GO:0045719)2.15582112
161antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.15345885
162motile cilium assembly (GO:0044458)2.14866079
163face development (GO:0060324)2.14625589
164peptidyl-lysine dimethylation (GO:0018027)2.14295563
165peptidyl-lysine trimethylation (GO:0018023)2.14002810
166negative regulation of translation, ncRNA-mediated (GO:0040033)2.13427009
167regulation of translation, ncRNA-mediated (GO:0045974)2.13427009
168negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.13427009
169germ cell development (GO:0007281)2.13400720
170establishment of nucleus localization (GO:0040023)2.13272708
171protein K48-linked deubiquitination (GO:0071108)2.13227154
172regulation of DNA endoreduplication (GO:0032875)2.12579051
173hippo signaling (GO:0035329)2.12396443
174NLS-bearing protein import into nucleus (GO:0006607)2.12392852
175vesicle coating (GO:0006901)2.11997520
176ectodermal placode formation (GO:0060788)2.11546221
177appendage development (GO:0048736)2.10416902
178limb development (GO:0060173)2.10416902

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.62896732
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.20563002
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.14005889
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.89619455
5GBX2_23144817_ChIP-Seq_PC3_Human2.63880751
6CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.52805597
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.44642814
8STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.37513902
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.31790445
10TAF15_26573619_Chip-Seq_HEK293_Human2.27183623
11STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.15236371
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.01454260
13ZNF217_24962896_ChIP-Seq_MCF-7_Human1.98308692
14ZFP57_27257070_Chip-Seq_ESCs_Mouse1.89896215
15NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.89527349
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.88504821
17OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.84564513
18ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.82593025
19SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.82355985
20PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.80903031
21POU3F2_20337985_ChIP-ChIP_501MEL_Human1.78756363
22AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.77041995
23SMAD_19615063_ChIP-ChIP_OVARY_Human1.74147209
24FLI1_27457419_Chip-Seq_LIVER_Mouse1.69409676
25P300_19829295_ChIP-Seq_ESCs_Human1.62672700
26NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.57818253
27NRF2_20460467_ChIP-Seq_MEFs_Mouse1.57818253
28KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.56286055
29FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.53213335
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.52999617
31RBPJ_22232070_ChIP-Seq_NCS_Mouse1.51177731
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.51055041
33TP53_18474530_ChIP-ChIP_U2OS_Human1.49764617
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49129338
35AR_21909140_ChIP-Seq_LNCAP_Human1.49094484
36TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.46500078
37PKCTHETA_26484144_Chip-Seq_BREAST_Human1.46182963
38SMAD3_21741376_ChIP-Seq_EPCs_Human1.44501001
39NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.44420876
40E2F7_22180533_ChIP-Seq_HELA_Human1.43724826
41PCGF2_27294783_Chip-Seq_NPCs_Mouse1.42017764
42EP300_21415370_ChIP-Seq_HL-1_Mouse1.40782568
43CDX2_19796622_ChIP-Seq_MESCs_Mouse1.40036236
44MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.39966837
45SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.39685140
46YAP1_20516196_ChIP-Seq_MESCs_Mouse1.39180970
47CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.38850020
48ESR1_20079471_ChIP-ChIP_T-47D_Human1.38372863
49STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.38193160
50NR3C1_21868756_ChIP-Seq_MCF10A_Human1.37917540
51FOXM1_26456572_ChIP-Seq_MCF-7_Human1.37682404
52NANOG_18555785_Chip-Seq_ESCs_Mouse1.36227623
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33581793
54SMAD3_21741376_ChIP-Seq_HESCs_Human1.33277056
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.33051949
56FOXO3_23340844_ChIP-Seq_DLD1_Human1.30855820
57RUNX_20019798_ChIP-Seq_JUKART_Human1.30640316
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30317139
59TOP2B_26459242_ChIP-Seq_MCF-7_Human1.29340188
60FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.28833164
61IRF8_22096565_ChIP-ChIP_GC-B_Human1.27113618
62CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26447131
63CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.25471161
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25178622
65CBP_20019798_ChIP-Seq_JUKART_Human1.25178622
66TCF4_18268006_ChIP-ChIP_LS174T_Human1.24859327
67TP63_19390658_ChIP-ChIP_HaCaT_Human1.24116485
68Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.23944439
69TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.23490601
70TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22680129
71ARNT_22903824_ChIP-Seq_MCF-7_Human1.22498680
72EZH2_27294783_Chip-Seq_NPCs_Mouse1.22067219
73EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.21005540
74PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19387463
75SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19238842
76UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18674976
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.18122563
78BRD4_25478319_ChIP-Seq_HGPS_Human1.17431385
79SOX9_26525672_Chip-Seq_HEART_Mouse1.17097978
80FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.16981885
81AHR_22903824_ChIP-Seq_MCF-7_Human1.16795992
82TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.16687002
83SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.16458168
84CJUN_26792858_Chip-Seq_BT549_Human1.15992909
85SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.15726715
86SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.15726715
87IGF1R_20145208_ChIP-Seq_DFB_Human1.15689971
88TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15250981
89POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.15250981
90DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13543884
91VDR_24787735_ChIP-Seq_THP-1_Human1.13325612
92SALL4_18804426_ChIP-ChIP_XEN_Mouse1.12394451
93HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.12053488
94FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.11982361
95FOXM1_23109430_ChIP-Seq_U2OS_Human1.11264133
96CDX2_22108803_ChIP-Seq_LS180_Human1.11128041
97TP53_16413492_ChIP-PET_HCT116_Human1.09395523
98CMYC_18555785_Chip-Seq_ESCs_Mouse1.09125590
99TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.09100828
100CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.08956346
101KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08767767
102E2F1_18555785_Chip-Seq_ESCs_Mouse1.08767211
103RUNX2_22187159_ChIP-Seq_PCA_Human1.08651405
104TCF4_23295773_ChIP-Seq_U87_Human1.08265773
105FLI1_21867929_ChIP-Seq_TH2_Mouse1.08257496
106MYB_26560356_Chip-Seq_TH2_Human1.07761512
107FUS_26573619_Chip-Seq_HEK293_Human1.07465289
108P53_22387025_ChIP-Seq_ESCs_Mouse1.07426889
109AR_25329375_ChIP-Seq_VCAP_Human1.07262528
110STAT3_23295773_ChIP-Seq_U87_Human1.07242626
111TP63_23658742_ChIP-Seq_EP156T_Human1.07237893
112GATA1_22025678_ChIP-Seq_K562_Human1.06770655
113KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.06715149
114KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.06715149
115SMAD4_21799915_ChIP-Seq_A2780_Human1.06300190
116ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.06186070
117FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.04695591
118OCT4_18555785_Chip-Seq_ESCs_Mouse1.02472254
119IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.01861083
120EWS_26573619_Chip-Seq_HEK293_Human1.01045688
121WT1_19549856_ChIP-ChIP_CCG9911_Human1.00147011
122CTNNB1_20460455_ChIP-Seq_HCT116_Human0.99862254
123IRF8_27001747_Chip-Seq_BMDM_Mouse0.99563375
124BCAT_22108803_ChIP-Seq_LS180_Human0.99350760
125ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.99345985
126SUZ12_18555785_Chip-Seq_ESCs_Mouse0.99162153
127PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.98852072
128FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.98606187
129EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.97591538
130GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.97234899
131GATA3_27048872_Chip-Seq_THYMUS_Human0.96747562
132ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.96554607
133GATA2_21666600_ChIP-Seq_HMVEC_Human0.94904092
134STAT3_18555785_Chip-Seq_ESCs_Mouse0.94508900
135NFIB_24661679_ChIP-Seq_LUNG_Mouse0.93789601
136FOXA1_25552417_ChIP-Seq_VCAP_Human0.93783270
137TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.93736556
138NMYC_18555785_Chip-Seq_ESCs_Mouse0.92261414
139PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92111476
140CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.92034528
141ISL1_27105846_Chip-Seq_CPCs_Mouse0.91642333
142ER_23166858_ChIP-Seq_MCF-7_Human0.90971423
143P300_18555785_Chip-Seq_ESCs_Mouse0.90935115

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002009_preneoplasia3.35116096
2MP0000569_abnormal_digit_pigmentation3.18416216
3MP0002877_abnormal_melanocyte_morpholog3.15495208
4MP0005410_abnormal_fertilization2.87509654
5MP0003950_abnormal_plasma_membrane2.78452423
6MP0003300_gastrointestinal_ulcer2.74266844
7MP0010234_abnormal_vibrissa_follicle2.71774184
8MP0010352_gastrointestinal_tract_polyps2.68164000
9MP0008877_abnormal_DNA_methylation2.46200704
10MP0002166_altered_tumor_susceptibility2.36991851
11MP0005076_abnormal_cell_differentiation2.27540452
12MP0002006_tumorigenesis2.03441968
13MP0006054_spinal_hemorrhage2.00715173
14MP0004264_abnormal_extraembryonic_tissu1.96664279
15MP0009780_abnormal_chondrocyte_physiolo1.84495961
16MP0008057_abnormal_DNA_replication1.82714215
17MP0003045_fibrosis1.82641672
18MP0003385_abnormal_body_wall1.80207439
19MP0010307_abnormal_tumor_latency1.78997112
20MP0010678_abnormal_skin_adnexa1.69182244
21MP0005257_abnormal_intraocular_pressure1.63999562
22MP0001929_abnormal_gametogenesis1.63149082
23MP0000516_abnormal_urinary_system1.62158461
24MP0005367_renal/urinary_system_phenotyp1.62158461
25MP0002254_reproductive_system_inflammat1.62128310
26MP0003787_abnormal_imprinting1.58827532
27MP0002102_abnormal_ear_morphology1.57793361
28MP0010030_abnormal_orbit_morphology1.54087515
29MP0005310_abnormal_salivary_gland1.52396356
30MP0004808_abnormal_hematopoietic_stem1.49900585
31MP0002233_abnormal_nose_morphology1.48999361
32MP0003755_abnormal_palate_morphology1.47118752
33MP0002909_abnormal_adrenal_gland1.41957284
34MP0003119_abnormal_digestive_system1.41725046
35MP0003221_abnormal_cardiomyocyte_apopto1.41021496
36MP0000383_abnormal_hair_follicle1.40016340
37MP0005409_darkened_coat_color1.37434629
38MP0003698_abnormal_male_reproductive1.37319358
39MP0009697_abnormal_copulation1.34667580
40MP0005197_abnormal_uvea_morphology1.33663564
41MP0003763_abnormal_thymus_physiology1.32976381
42MP0000647_abnormal_sebaceous_gland1.32971398
43MP0003183_abnormal_peptide_metabolism1.30015200
44MP0005248_abnormal_Harderian_gland1.29531023
45MP0000778_abnormal_nervous_system1.28899668
46MP0002928_abnormal_bile_duct1.27117659
47MP0000427_abnormal_hair_cycle1.26468373
48MP0002210_abnormal_sex_determination1.26459728
49MP0003942_abnormal_urinary_system1.25827765
50MP0008007_abnormal_cellular_replicative1.24772380
51MP0003115_abnormal_respiratory_system1.24540070
52MP0000537_abnormal_urethra_morphology1.23165729
53MP0002085_abnormal_embryonic_tissue1.21790149
54MP0004957_abnormal_blastocyst_morpholog1.20152914
55MP0001346_abnormal_lacrimal_gland1.19971303
56MP0001286_abnormal_eye_development1.19914687
57MP0003567_abnormal_fetal_cardiomyocyte1.19518089
58MP0001299_abnormal_eye_distance/1.18268996
59MP0005623_abnormal_meninges_morphology1.15316633
60MP0000613_abnormal_salivary_gland1.12599823
61MP0003890_abnormal_embryonic-extraembry1.11357025
62MP0001145_abnormal_male_reproductive1.10570513
63MP0000733_abnormal_muscle_development1.09602165
64MP0003091_abnormal_cell_migration1.08954662
65MP0000653_abnormal_sex_gland1.08716681
66MP0005380_embryogenesis_phenotype1.07880984
67MP0001672_abnormal_embryogenesis/_devel1.07880984
68MP0003121_genomic_imprinting1.06916649
69MP0001188_hyperpigmentation1.06574532
70MP0002751_abnormal_autonomic_nervous1.06292266
71MP0002896_abnormal_bone_mineralization1.05850764
72MP0003878_abnormal_ear_physiology1.05719452
73MP0005377_hearing/vestibular/ear_phenot1.05719452
74MP0004947_skin_inflammation1.05061069
75MP0005193_abnormal_anterior_eye1.04807818
76MP0000534_abnormal_ureter_morphology1.04396967
77MP0000538_abnormal_urinary_bladder1.02443917
78MP0003861_abnormal_nervous_system1.01659332
79MP0003937_abnormal_limbs/digits/tail_de1.01563628
80MP0000762_abnormal_tongue_morphology1.01562702
81MP0002088_abnormal_embryonic_growth/wei1.00554646
82MP0001177_atelectasis0.99428675
83MP0003984_embryonic_growth_retardation0.99403707
84MP0001293_anophthalmia0.99277454
85MP0002693_abnormal_pancreas_physiology0.96759334
86MP0003566_abnormal_cell_adhesion0.95843144
87MP0003935_abnormal_craniofacial_develop0.95467874
88MP0006072_abnormal_retinal_apoptosis0.93829785
89MP0005220_abnormal_exocrine_pancreas0.93320850
90MP0000462_abnormal_digestive_system0.93141754
91MP0010386_abnormal_urinary_bladder0.92735955
92MP0002060_abnormal_skin_morphology0.92472404
93MP0003453_abnormal_keratinocyte_physiol0.91510174
94MP0001873_stomach_inflammation0.91251633
95MP0006292_abnormal_olfactory_placode0.90554008
96MP0000566_synostosis0.90497599
97MP0003868_abnormal_feces_composition0.90152056
98MP0000432_abnormal_head_morphology0.90110560
99MP0000627_abnormal_mammary_gland0.89707755
100MP0005275_abnormal_skin_tensile0.89561912
101MP0001697_abnormal_embryo_size0.89497830
102MP0005085_abnormal_gallbladder_physiolo0.89068446
103MP0005503_abnormal_tendon_morphology0.88968792
104MP0002971_abnormal_brown_adipose0.88422355
105MP0005671_abnormal_response_to0.87992561
106MP0009703_decreased_birth_body0.87647547
107MP0002697_abnormal_eye_size0.86587717
108MP0004272_abnormal_basement_membrane0.86365190
109MP0003941_abnormal_skin_development0.86266602
110MP0002111_abnormal_tail_morphology0.85555257
111MP0003943_abnormal_hepatobiliary_system0.84761413
112MP0000377_abnormal_hair_follicle0.84708000
113MP0002177_abnormal_outer_ear0.84331020
114MP0002116_abnormal_craniofacial_bone0.84120832
115MP0002184_abnormal_innervation0.82638404
116MP0002092_abnormal_eye_morphology0.82632123
117MP0002938_white_spotting0.82449277
118MP0000685_abnormal_immune_system0.81507995
119MP0009053_abnormal_anal_canal0.81009960
120MP0002098_abnormal_vibrissa_morphology0.80445417
121MP0005187_abnormal_penis_morphology0.79979135
122MP0002084_abnormal_developmental_patter0.79219811
123MP0001730_embryonic_growth_arrest0.78851494
124MP0002168_other_aberrant_phenotype0.78654312
125MP0002925_abnormal_cardiovascular_devel0.78420513
126MP0001944_abnormal_pancreas_morphology0.78202983
127MP0005647_abnormal_sex_gland0.77934748
128MP0003936_abnormal_reproductive_system0.77711680
129MP0002109_abnormal_limb_morphology0.77561723
130MP0000428_abnormal_craniofacial_morphol0.77400301
131MP0008932_abnormal_embryonic_tissue0.77014513
132MP0002796_impaired_skin_barrier0.76973564
133MP0009115_abnormal_fat_cell0.76640825
134MP0010094_abnormal_chromosome_stability0.76363931
135MP0001851_eye_inflammation0.76264267
136MP0005508_abnormal_skeleton_morphology0.76051437
137MP0008961_abnormal_basal_metabolism0.75520588
138MP0000703_abnormal_thymus_morphology0.75519732
139MP0002086_abnormal_extraembryonic_tissu0.75473187
140MP0003448_altered_tumor_morphology0.75238836
141MP0008438_abnormal_cutaneous_collagen0.75106919
142MP0002282_abnormal_trachea_morphology0.73983007
143MP0001119_abnormal_female_reproductive0.73648663
144MP0002161_abnormal_fertility/fecundity0.73570296
145MP0004134_abnormal_chest_morphology0.73546243
146MP0001879_abnormal_lymphatic_vessel0.73486324
147MP0002115_abnormal_skeleton_extremities0.72955693
148MP0001835_abnormal_antigen_presentation0.71758202
149MP0008058_abnormal_DNA_repair0.71571361
150MP0001790_abnormal_immune_system0.71107183
151MP0005387_immune_system_phenotype0.71107183
152MP0003795_abnormal_bone_structure0.70667762
153MP0003705_abnormal_hypodermis_morpholog0.70594296
154MP0004197_abnormal_fetal_growth/weight/0.70370656

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.85207239
2Urethral obstruction (HP:0000796)4.69538565
3Dynein arm defect of respiratory motile cilia (HP:0012255)3.49270353
4Absent/shortened dynein arms (HP:0200106)3.49270353
5Renal cortical cysts (HP:0000803)3.41830281
6Proximal tubulopathy (HP:0000114)3.41574708
7Hepatoblastoma (HP:0002884)3.34599235
8Abnormality of the fingertips (HP:0001211)3.12488598
9Volvulus (HP:0002580)3.07039158
10Hypoplastic labia majora (HP:0000059)2.89609523
11Abnormal respiratory motile cilium physiology (HP:0012261)2.87391819
12Papillary thyroid carcinoma (HP:0002895)2.84766067
13Chronic bronchitis (HP:0004469)2.77736365
14Absent frontal sinuses (HP:0002688)2.75469980
15Lip pit (HP:0100267)2.69830119
16Rhinitis (HP:0012384)2.62098845
17Abnormality of the labia majora (HP:0012881)2.61548590
18Progressive external ophthalmoplegia (HP:0000590)2.60267743
19Aortic aneurysm (HP:0004942)2.58736470
20Abnormality of the ischium (HP:0003174)2.55586980
21Curly hair (HP:0002212)2.55489163
22Right ventricular cardiomyopathy (HP:0011663)2.54852602
23Hydroureter (HP:0000072)2.34934546
24Macroorchidism (HP:0000053)2.31486959
25Hypoplastic ischia (HP:0003175)2.30284362
26Abnormality of the nasal septum (HP:0000419)2.29258113
27Neoplasm of the adrenal cortex (HP:0100641)2.26572986
28Heterotopia (HP:0002282)2.24423312
29Capillary hemangiomas (HP:0005306)2.24105036
30Poor coordination (HP:0002370)2.20978147
31Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.15416296
32Bronchiectasis (HP:0002110)2.15358283
33Nephronophthisis (HP:0000090)2.15060942
34Vaginal atresia (HP:0000148)2.14585669
35Genital tract atresia (HP:0001827)2.10828684
36Acute myeloid leukemia (HP:0004808)2.10377115
37Infertility (HP:0000789)2.08511169
38Alacrima (HP:0000522)2.07032869
39Hematochezia (HP:0002573)2.06464662
40Nasal polyposis (HP:0100582)2.06069426
41Cystic hygroma (HP:0000476)2.05897952
42Disinhibition (HP:0000734)2.05758295
43Large earlobe (HP:0009748)2.04806437
44Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.04289554
45Decreased lacrimation (HP:0000633)2.04152407
46Abnormality of the renal medulla (HP:0100957)2.03746211
47Congenital primary aphakia (HP:0007707)2.03574838
48Narrow palate (HP:0000189)2.01642959
49Bronchitis (HP:0012387)1.98216861
50Abnormal ciliary motility (HP:0012262)1.97992027
51Subacute progressive viral hepatitis (HP:0006572)1.97714211
52Abnormal respiratory epithelium morphology (HP:0012253)1.96443657
53Abnormal respiratory motile cilium morphology (HP:0005938)1.96443657
54Truncal obesity (HP:0001956)1.95434824
55Aortic dissection (HP:0002647)1.92014999
56Medial flaring of the eyebrow (HP:0010747)1.91505132
57Abnormality of the frontal sinuses (HP:0002687)1.91444991
58Male infertility (HP:0003251)1.91322557
59Thyroid carcinoma (HP:0002890)1.90812878
60Rectal prolapse (HP:0002035)1.90565449
61Cupped ear (HP:0000378)1.88819328
62Gait imbalance (HP:0002141)1.88379890
63Midline defect of the nose (HP:0004122)1.87986710
64Ankyloglossia (HP:0010296)1.85934301
65Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.85769436
66Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.84626192
67Progressive inability to walk (HP:0002505)1.83107523
68Vitreoretinal degeneration (HP:0000655)1.82153064
69Vertebral arch anomaly (HP:0008438)1.81109255
70Exotropia (HP:0000577)1.80757097
71Persistence of primary teeth (HP:0006335)1.80172401
72Abnormality of the renal cortex (HP:0011035)1.80062474
73Flat acetabular roof (HP:0003180)1.79067356
74Absent eyebrow (HP:0002223)1.74464781
75Nephrogenic diabetes insipidus (HP:0009806)1.74180568
76Cubitus valgus (HP:0002967)1.73547464
77Myelomeningocele (HP:0002475)1.73281748
78Syringomyelia (HP:0003396)1.72799740
79Spinal cord lesions (HP:0100561)1.72799740
80Molar tooth sign on MRI (HP:0002419)1.72471332
81Abnormality of midbrain morphology (HP:0002418)1.72471332
82Abnormality of the epiphyses of the hand (HP:0005924)1.70866965
83Missing ribs (HP:0000921)1.70678440
84Prostate neoplasm (HP:0100787)1.70368350
85Long eyelashes (HP:0000527)1.70139996
86Abnormal pancreas size (HP:0012094)1.70049930
87Short 4th metacarpal (HP:0010044)1.69764073
88Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.69764073
89Embryonal renal neoplasm (HP:0011794)1.68472911
90Arterial tortuosity (HP:0005116)1.66765149
91Preaxial foot polydactyly (HP:0001841)1.66479047
92Deep philtrum (HP:0002002)1.64852346
93Pancreatic cysts (HP:0001737)1.64562751
94Xerostomia (HP:0000217)1.63315517
95Spondylolisthesis (HP:0003302)1.62909808
96Abnormal foot bone ossification (HP:0010675)1.61905605
97Aplasia/Hypoplasia of the tongue (HP:0010295)1.61278459
98Tubulointerstitial nephritis (HP:0001970)1.59521194
99Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.59405916
100Overgrowth (HP:0001548)1.59184063
101Nephroblastoma (Wilms tumor) (HP:0002667)1.59128822
102Leiomyosarcoma (HP:0100243)1.58505168
103Uterine leiomyosarcoma (HP:0002891)1.58505168
104Neoplasm of the oral cavity (HP:0100649)1.57867686
105Dislocated radial head (HP:0003083)1.57766046
106Intrahepatic cholestasis (HP:0001406)1.57683874
107Drooling (HP:0002307)1.57616422
108Bifid tongue (HP:0010297)1.57592245
109Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.57554771
110Intellectual disability, moderate (HP:0002342)1.57149969
111Broad palm (HP:0001169)1.56999473
112Partial agenesis of the corpus callosum (HP:0001338)1.55912008
113Ectopic kidney (HP:0000086)1.55854781
114Sandal gap (HP:0001852)1.55527429
115Broad foot (HP:0001769)1.54993118
116Neoplasm of the thyroid gland (HP:0100031)1.54254159
117Transitional cell carcinoma of the bladder (HP:0006740)1.53884807
118Inability to walk (HP:0002540)1.53749827
119Abnormality of oral frenula (HP:0000190)1.53601826
120Retrobulbar optic neuritis (HP:0100654)1.53066872
121Optic neuritis (HP:0100653)1.53066872
12211 pairs of ribs (HP:0000878)1.52079516
123Thick eyebrow (HP:0000574)1.51313206
124Prominent nose (HP:0000448)1.51294528
125Short foot (HP:0001773)1.50577612
126True hermaphroditism (HP:0010459)1.49400224
127Vascular tortuosity (HP:0004948)1.49319513
128T lymphocytopenia (HP:0005403)1.48629489
129Abnormality of the pubic bones (HP:0003172)1.48405519
130Osteolytic defects of the hand bones (HP:0009699)1.48299390
131Osteolytic defects of the phalanges of the hand (HP:0009771)1.48299390
132Milia (HP:0001056)1.47906411
133Omphalocele (HP:0001539)1.47667475
134Exostoses (HP:0100777)1.47629316
135Overlapping toe (HP:0001845)1.47546921
136Aqueductal stenosis (HP:0002410)1.47167843
137Anal stenosis (HP:0002025)1.47122275
138Biliary tract neoplasm (HP:0100574)1.46929547
139Thin upper lip vermilion (HP:0000219)1.46222444
140Asymmetry of the thorax (HP:0001555)1.46111465
141Bladder neoplasm (HP:0009725)1.46008251
142Bladder carcinoma (HP:0002862)1.46008251
143Hypoplasia of the iris (HP:0007676)1.45541973
144Recurrent bronchitis (HP:0002837)1.45203858
145Malignant gastrointestinal tract tumors (HP:0006749)1.44621779
146Gastrointestinal carcinoma (HP:0002672)1.44621779
147Thickened calvaria (HP:0002684)1.44409599
148Abnormality of the radial head (HP:0003995)1.44318206
149Ureteral obstruction (HP:0006000)1.44209196
150Smooth philtrum (HP:0000319)1.44035746
151Hypoplasia of dental enamel (HP:0006297)1.43960651
152Fibular hypoplasia (HP:0003038)1.43960300
153Short metatarsal (HP:0010743)1.43946875
154Broad ribs (HP:0000885)1.43938941
155Autoimmune hemolytic anemia (HP:0001890)1.43771173
156Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.43385030
157Abnormality of salivation (HP:0100755)1.43241726
158Neoplasm of the tracheobronchial system (HP:0100552)1.43150664
159Stage 5 chronic kidney disease (HP:0003774)1.42788520
160Broad alveolar ridges (HP:0000187)1.42433194
161Breast carcinoma (HP:0003002)1.42209837
162Abnormality of the nasal mucosa (HP:0000433)1.41736303
163Chromsome breakage (HP:0040012)1.41076607
164Cerebral aneurysm (HP:0004944)1.40754085
165Arterial thrombosis (HP:0004420)1.39380486
166Glucose intolerance (HP:0000833)1.38419377
167Insulin-resistant diabetes mellitus (HP:0000831)1.38339692
168Abnormality of T cell number (HP:0011839)1.38313845
169Facial hemangioma (HP:0000329)1.38177186
170Recurrent sinusitis (HP:0011108)1.38029011
171Inappropriate behavior (HP:0000719)1.37986838
172Aortic regurgitation (HP:0001659)1.37864044
173Short thorax (HP:0010306)1.33833359

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK3.94435471
2LATS13.62343605
3TAOK33.55695842
4CDK122.77423109
5AKT32.10726340
6FGFR32.02508298
7STK32.02123590
8NEK112.4426620
9NUAK11.98643060
10PRKD31.83771711
11INSRR1.76238571
12EPHA31.72859678
13MAP3K141.70474504
14BRD41.68813330
15PDK31.66231422
16PDK41.66231422
17PASK1.63682544
18CASK1.59180744
19CDK91.53320467
20PDK21.46979459
21STK101.46647932
22JAK31.46081107
23MST41.44017994
24PKN21.40426116
25FGFR21.38443287
26CHUK1.38087767
27BCR1.36311752
28LATS21.35272536
29EPHB11.34979890
30STK391.30033495
31TRPM71.29913699
32TAF11.29459337
33PDGFRB1.27480998
34MAPK151.25043404
35MAP4K21.24379633
36CAMK1G1.23083470
37MAP3K21.22619787
38PDGFRA1.22378611
39UHMK11.22014996
40HIPK21.21696468
41TXK1.21614161
42WNK11.20711961
43NLK1.19929269
44JAK11.18305902
45MELK1.16564062
46MKNK21.12452334
47ROCK21.10236192
48ERBB31.09778421
49SIK31.08669252
50PTK61.07491131
51ITK1.05548550
52CDC71.03679436
53EIF2AK31.03676389
54TYK21.01556147
55SCYL20.99461993
56PLK20.98494587
57DMPK0.98144636
58TRIM280.96409134
59EPHA20.96045722
60CAMK1D0.93530576
61CDK60.91565126
62WNK40.90180578
63BMPR1B0.88177933
64MET0.86674970
65ATM0.86555373
66SGK20.85930765
67SRPK10.85341650
68PLK40.83519703
69MKNK10.82292182
70RPS6KA40.81786821
71TNIK0.80868247
72MTOR0.80845120
73SGK30.80088022
74NEK90.80084643
75RIPK10.80043386
76NEK60.79367185
77IRAK10.78702668
78MAP3K40.75798351
79MAPKAPK50.74941670
80FER0.74869881
81RET0.74865496
82MAPK130.74156204
83ATR0.72893340
84IKBKE0.71202258
85DYRK1B0.68070508
86TESK10.67197114
87STK240.66348846
88STK38L0.65690452
89BMPR20.65257912
90DDR20.62838063
91LMTK20.62363158
92BRSK20.62299342
93KSR10.62168306
94PBK0.61353348
95CSK0.61240751
96CHEK20.60839598
97NEK20.60708960
98ERBB40.60682180
99EEF2K0.59925209
100CDK30.59727559
101CHEK10.57857967
102IKBKB0.57839894
103TYRO30.56322341
104FGFR10.56129168
105WNK30.56027870
106PTK2B0.53537644
107MAP3K60.52654062
108YES10.51034813
109MAP3K120.50674026
110GSK3A0.49598554
111CDK80.49479373
112WEE10.48388710
113PRKAA20.48287579
114PTK20.48117113
115CDC42BPA0.47978307
116PNCK0.47929553
117PIM10.46546708
118STK40.46389814
119FLT30.45697962
120PAK20.43948999
121PRKACB0.43526381
122TGFBR20.43454934
123PIK3CA0.43090579
124TEC0.42889772
125MAPK140.42692347
126PAK30.42607761
127MST1R0.42079387
128CSNK1D0.40219520
129EGFR0.39200390
130MAPK10.38918353
131SGK10.38865877
132CDK70.38859981
133RPS6KB10.38104541
134AKT10.38000328
135ZAK0.37827547
136CSNK1E0.37361997
137STK380.36780536
138MAPK100.36538062
139CSNK1G20.34871235
140PLK30.33491326
141CSNK1G10.33401893
142CAMK2B0.33151509
143EIF2AK10.30111658
144MAPK70.29070203
145MAP3K100.28752582
146TTK0.26757435
147AURKB0.25967302
148ACVR1B0.23469220
149PRKCE0.23024537
150EIF2AK20.22610058
151CAMK40.22483311
152SGK4940.22446329
153SGK2230.22446329
154DYRK30.21585600
155CSNK1A10.21044314

Predicted pathways (KEGG)

RankGene SetZ-score
1Dorso-ventral axis formation_Homo sapiens_hsa043201.95918470
2Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.85339574
3Hedgehog signaling pathway_Homo sapiens_hsa043401.85083016
4Sphingolipid metabolism_Homo sapiens_hsa006001.66238591
5Thyroid cancer_Homo sapiens_hsa052161.59901828
6Antigen processing and presentation_Homo sapiens_hsa046121.56057368
7Basal transcription factors_Homo sapiens_hsa030221.50686581
8NF-kappa B signaling pathway_Homo sapiens_hsa040641.43506403
9Axon guidance_Homo sapiens_hsa043601.43054600
10Small cell lung cancer_Homo sapiens_hsa052221.41173270
11Maturity onset diabetes of the young_Homo sapiens_hsa049501.39413570
12Prostate cancer_Homo sapiens_hsa052151.38995548
13NOD-like receptor signaling pathway_Homo sapiens_hsa046211.35187284
14Graft-versus-host disease_Homo sapiens_hsa053321.34955498
15Adherens junction_Homo sapiens_hsa045201.33144988
16Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.32821150
17Toxoplasmosis_Homo sapiens_hsa051451.31546286
18TNF signaling pathway_Homo sapiens_hsa046681.30008850
19Pancreatic cancer_Homo sapiens_hsa052121.29536980
20MicroRNAs in cancer_Homo sapiens_hsa052061.28006874
21Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.26318609
22Steroid biosynthesis_Homo sapiens_hsa001001.24325495
23TGF-beta signaling pathway_Homo sapiens_hsa043501.22855816
24Chronic myeloid leukemia_Homo sapiens_hsa052201.22786015
25Transcriptional misregulation in cancer_Homo sapiens_hsa052021.22696883
26Tight junction_Homo sapiens_hsa045301.21118680
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.14217660
28Measles_Homo sapiens_hsa051621.14149855
29Osteoclast differentiation_Homo sapiens_hsa043801.14097794
30Melanoma_Homo sapiens_hsa052181.13663675
31Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12478505
32T cell receptor signaling pathway_Homo sapiens_hsa046601.11282345
33Type II diabetes mellitus_Homo sapiens_hsa049301.09465812
34Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.09393520
35Prolactin signaling pathway_Homo sapiens_hsa049171.08478487
36Type I diabetes mellitus_Homo sapiens_hsa049401.05820232
37ECM-receptor interaction_Homo sapiens_hsa045121.04718650
38AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.03214883
39Focal adhesion_Homo sapiens_hsa045101.02658714
40Melanogenesis_Homo sapiens_hsa049161.01070041
41Carbohydrate digestion and absorption_Homo sapiens_hsa049731.00029224
42Propanoate metabolism_Homo sapiens_hsa006400.99595600
43Hematopoietic cell lineage_Homo sapiens_hsa046400.99523508
44Leishmaniasis_Homo sapiens_hsa051400.98676842
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.98182412
46Allograft rejection_Homo sapiens_hsa053300.97661824
47FoxO signaling pathway_Homo sapiens_hsa040680.97142116
48Protein export_Homo sapiens_hsa030600.97075659
49mTOR signaling pathway_Homo sapiens_hsa041500.95978085
50Viral carcinogenesis_Homo sapiens_hsa052030.95739748
51B cell receptor signaling pathway_Homo sapiens_hsa046620.95331525
52Hepatitis B_Homo sapiens_hsa051610.94843747
53Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.94666319
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.94506677
55PI3K-Akt signaling pathway_Homo sapiens_hsa041510.93703043
56Long-term depression_Homo sapiens_hsa047300.93162427
57HTLV-I infection_Homo sapiens_hsa051660.92854941
58Fanconi anemia pathway_Homo sapiens_hsa034600.92262044
59Herpes simplex infection_Homo sapiens_hsa051680.92220529
60Jak-STAT signaling pathway_Homo sapiens_hsa046300.91812811
61Proteoglycans in cancer_Homo sapiens_hsa052050.91258632
62RNA transport_Homo sapiens_hsa030130.90816592
63Influenza A_Homo sapiens_hsa051640.89043410
64p53 signaling pathway_Homo sapiens_hsa041150.88769571
65Hippo signaling pathway_Homo sapiens_hsa043900.86942829
66Cell cycle_Homo sapiens_hsa041100.86641824
67Endometrial cancer_Homo sapiens_hsa052130.86524585
68Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.86051421
69RNA degradation_Homo sapiens_hsa030180.86041108
70Fatty acid biosynthesis_Homo sapiens_hsa000610.85491803
71Wnt signaling pathway_Homo sapiens_hsa043100.85166165
72mRNA surveillance pathway_Homo sapiens_hsa030150.84724207
73Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84200960
74Choline metabolism in cancer_Homo sapiens_hsa052310.83757759
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.82896011
76Colorectal cancer_Homo sapiens_hsa052100.82034739
77Amoebiasis_Homo sapiens_hsa051460.81795082
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81726304
79Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.81244678
80Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.80936243
81Insulin resistance_Homo sapiens_hsa049310.80543650
82N-Glycan biosynthesis_Homo sapiens_hsa005100.80386991
83Legionellosis_Homo sapiens_hsa051340.79688741
84Regulation of actin cytoskeleton_Homo sapiens_hsa048100.79434312
85Estrogen signaling pathway_Homo sapiens_hsa049150.79266765
86Renal cell carcinoma_Homo sapiens_hsa052110.78931266
87Toll-like receptor signaling pathway_Homo sapiens_hsa046200.77718749
88Protein digestion and absorption_Homo sapiens_hsa049740.77393656
89Inositol phosphate metabolism_Homo sapiens_hsa005620.77114068
90Leukocyte transendothelial migration_Homo sapiens_hsa046700.76783041
91Viral myocarditis_Homo sapiens_hsa054160.75224562
92Nitrogen metabolism_Homo sapiens_hsa009100.75191209
93Malaria_Homo sapiens_hsa051440.75144069
94Pathways in cancer_Homo sapiens_hsa052000.74462420
95Glioma_Homo sapiens_hsa052140.73920961
96Autoimmune thyroid disease_Homo sapiens_hsa053200.72564381
97Cocaine addiction_Homo sapiens_hsa050300.72099223
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.71451638
99Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.71063959
100Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.70818542
101Chemokine signaling pathway_Homo sapiens_hsa040620.70533823
102Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.70257092
103Non-homologous end-joining_Homo sapiens_hsa034500.70205607
104Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.70118005
105Circadian rhythm_Homo sapiens_hsa047100.69637867
106Acute myeloid leukemia_Homo sapiens_hsa052210.68285792
107Apoptosis_Homo sapiens_hsa042100.67585605
108Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67551674
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65791920
110ErbB signaling pathway_Homo sapiens_hsa040120.65299849
111Thyroid hormone synthesis_Homo sapiens_hsa049180.64893115
112cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64234596
113MAPK signaling pathway_Homo sapiens_hsa040100.64082066
114Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.64019691
115Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63976894
116Non-small cell lung cancer_Homo sapiens_hsa052230.63717997
117AMPK signaling pathway_Homo sapiens_hsa041520.63533313
118Basal cell carcinoma_Homo sapiens_hsa052170.63048960
119Intestinal immune network for IgA production_Homo sapiens_hsa046720.62885067
120Neurotrophin signaling pathway_Homo sapiens_hsa047220.62739633
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.62723710
122Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.62385436
123Lysine degradation_Homo sapiens_hsa003100.62341095
124Platelet activation_Homo sapiens_hsa046110.62338369
125Notch signaling pathway_Homo sapiens_hsa043300.62080037
126Glucagon signaling pathway_Homo sapiens_hsa049220.61949191
127Glycerophospholipid metabolism_Homo sapiens_hsa005640.60972581
128Ovarian steroidogenesis_Homo sapiens_hsa049130.60884935
129Pancreatic secretion_Homo sapiens_hsa049720.60601450
130Hepatitis C_Homo sapiens_hsa051600.60488341
131Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60175317
132alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.57839393
133Ras signaling pathway_Homo sapiens_hsa040140.57010056
134Fatty acid metabolism_Homo sapiens_hsa012120.55644469
135Oocyte meiosis_Homo sapiens_hsa041140.54801729
136Taste transduction_Homo sapiens_hsa047420.53046857
137Rap1 signaling pathway_Homo sapiens_hsa040150.52892716
138Selenocompound metabolism_Homo sapiens_hsa004500.51987974
139Gap junction_Homo sapiens_hsa045400.51247751
140Central carbon metabolism in cancer_Homo sapiens_hsa052300.50527394
141Phospholipase D signaling pathway_Homo sapiens_hsa040720.48233880
142Butanoate metabolism_Homo sapiens_hsa006500.48191349
143Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.47531106
144Insulin secretion_Homo sapiens_hsa049110.46949935
145Steroid hormone biosynthesis_Homo sapiens_hsa001400.46092913
146Regulation of autophagy_Homo sapiens_hsa041400.46008910
147Renin secretion_Homo sapiens_hsa049240.45054685

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