SULT2A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.58102650
2L-phenylalanine catabolic process (GO:0006559)7.58102650
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.23010223
4L-phenylalanine metabolic process (GO:0006558)7.23010223
5triglyceride-rich lipoprotein particle remodeling (GO:0034370)7.14188648
6epoxygenase P450 pathway (GO:0019373)6.86812623
7aromatic amino acid family catabolic process (GO:0009074)6.57444527
8omega-hydroxylase P450 pathway (GO:0097267)6.31102377
9high-density lipoprotein particle remodeling (GO:0034375)6.21671624
10alpha-linolenic acid metabolic process (GO:0036109)5.92899671
11negative regulation of fibrinolysis (GO:0051918)5.62445577
12kynurenine metabolic process (GO:0070189)5.61703955
13tryptophan catabolic process (GO:0006569)5.61694176
14indole-containing compound catabolic process (GO:0042436)5.61694176
15indolalkylamine catabolic process (GO:0046218)5.61694176
16regulation of cholesterol esterification (GO:0010872)5.60455674
17cellular response to follicle-stimulating hormone stimulus (GO:0071372)5.45647645
18bile acid biosynthetic process (GO:0006699)5.44878938
19urea cycle (GO:0000050)5.44311222
20urea metabolic process (GO:0019627)5.44311222
21glyoxylate metabolic process (GO:0046487)5.44174128
22peptidyl-glutamic acid carboxylation (GO:0017187)5.42134914
23protein carboxylation (GO:0018214)5.42134914
24androgen biosynthetic process (GO:0006702)5.40717479
25reverse cholesterol transport (GO:0043691)5.35518323
26tryptophan metabolic process (GO:0006568)5.34941487
27regulation of fibrinolysis (GO:0051917)5.33014779
28sulfur amino acid catabolic process (GO:0000098)5.29722637
29cysteine metabolic process (GO:0006534)5.25917716
30serine family amino acid catabolic process (GO:0009071)5.24796957
31protein-lipid complex remodeling (GO:0034368)5.22302157
32macromolecular complex remodeling (GO:0034367)5.22302157
33plasma lipoprotein particle remodeling (GO:0034369)5.22302157
34oxidative demethylation (GO:0070989)5.18519746
35negative regulation of sterol transport (GO:0032372)5.15798839
36negative regulation of cholesterol transport (GO:0032375)5.15798839
37phospholipid efflux (GO:0033700)5.10612109
38cellular ketone body metabolic process (GO:0046950)5.00954654
39nitrogen cycle metabolic process (GO:0071941)5.00034702
40tyrosine metabolic process (GO:0006570)4.90093451
41progesterone metabolic process (GO:0042448)4.89780867
42intestinal cholesterol absorption (GO:0030299)4.87387927
43regulation of triglyceride catabolic process (GO:0010896)4.83579916
44plasma lipoprotein particle clearance (GO:0034381)4.81599962
45aromatic amino acid family metabolic process (GO:0009072)4.78276938
46drug catabolic process (GO:0042737)4.77165246
47triglyceride homeostasis (GO:0070328)4.74756659
48acylglycerol homeostasis (GO:0055090)4.74756659
49amino-acid betaine metabolic process (GO:0006577)4.72635958
50* bile acid metabolic process (GO:0008206)4.71737950
51phenylpropanoid metabolic process (GO:0009698)4.70935418
52alpha-amino acid catabolic process (GO:1901606)4.62427415
53glucocorticoid biosynthetic process (GO:0006704)4.61108926
54low-density lipoprotein particle remodeling (GO:0034374)4.58786421
55cholesterol efflux (GO:0033344)4.56817941
56fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.52703882
57regulation of plasminogen activation (GO:0010755)4.48972287
58homocysteine metabolic process (GO:0050667)4.43276632
59lysine catabolic process (GO:0006554)4.37351152
60lysine metabolic process (GO:0006553)4.37351152
61glycine metabolic process (GO:0006544)4.36846220
62plasma lipoprotein particle assembly (GO:0034377)4.35602620
63C21-steroid hormone biosynthetic process (GO:0006700)4.34570678
64ketone body metabolic process (GO:1902224)4.33788578
65bile acid and bile salt transport (GO:0015721)4.33117261
66regulation of protein activation cascade (GO:2000257)4.30948813
67protein activation cascade (GO:0072376)4.30885251
68imidazole-containing compound metabolic process (GO:0052803)4.30455821
69cellular glucuronidation (GO:0052695)4.27656430
70ethanol metabolic process (GO:0006067)4.26414384
71cellular amino acid catabolic process (GO:0009063)4.24830514
72glutamate metabolic process (GO:0006536)4.24471503
73negative regulation of lipase activity (GO:0060192)4.22318375
74drug metabolic process (GO:0017144)4.20854992
75response to follicle-stimulating hormone (GO:0032354)4.20450463
76negative regulation of hemostasis (GO:1900047)4.18807285
77negative regulation of blood coagulation (GO:0030195)4.18807285
78complement activation, alternative pathway (GO:0006957)4.17378188
79glucocorticoid metabolic process (GO:0008211)4.16017133
80negative regulation of protein activation cascade (GO:2000258)4.14390928
81S-adenosylmethionine metabolic process (GO:0046500)4.11966886
82C21-steroid hormone metabolic process (GO:0008207)4.11081277
83benzene-containing compound metabolic process (GO:0042537)4.08666708
84flavonoid metabolic process (GO:0009812)4.06864128
85positive regulation of lipid catabolic process (GO:0050996)4.06640418
86serine family amino acid metabolic process (GO:0009069)4.06346892
87androgen metabolic process (GO:0008209)4.04863108
88short-chain fatty acid metabolic process (GO:0046459)4.04323087
89indolalkylamine metabolic process (GO:0006586)4.00716847
90arginine metabolic process (GO:0006525)4.00641241
91alkaloid metabolic process (GO:0009820)3.99564488
92serine family amino acid biosynthetic process (GO:0009070)3.98227267
93aldehyde catabolic process (GO:0046185)3.97630331
94regulation of humoral immune response (GO:0002920)3.96264156
95complement activation, classical pathway (GO:0006958)3.96012046
96acute-phase response (GO:0006953)3.93826725
97plasma lipoprotein particle organization (GO:0071827)3.93737172
98cellular biogenic amine catabolic process (GO:0042402)3.93228201
99amine catabolic process (GO:0009310)3.93228201
100dicarboxylic acid biosynthetic process (GO:0043650)3.92307901
101protein-lipid complex assembly (GO:0065005)3.91513766
102cellular modified amino acid catabolic process (GO:0042219)3.90963209
103complement activation (GO:0006956)3.90761496
104coenzyme catabolic process (GO:0009109)3.90441931
105positive regulation of triglyceride lipase activity (GO:0061365)3.89780073
106positive regulation of lipoprotein lipase activity (GO:0051006)3.89780073
107very-low-density lipoprotein particle assembly (GO:0034379)3.89531903
108fibrinolysis (GO:0042730)3.89524912
109response to phenylpropanoid (GO:0080184)3.87334206
110cholesterol homeostasis (GO:0042632)3.86182158
111regulation of complement activation (GO:0030449)3.84913966
112phospholipid homeostasis (GO:0055091)3.84676962
113estrogen biosynthetic process (GO:0006703)3.83532838
114negative regulation of coagulation (GO:0050819)3.80791295
115blood coagulation, intrinsic pathway (GO:0007597)3.80727106
116negative regulation of wound healing (GO:0061045)3.80087541
117sterol homeostasis (GO:0055092)3.79734535
118uronic acid metabolic process (GO:0006063)3.78450619
119glucuronate metabolic process (GO:0019585)3.78450619
120hormone catabolic process (GO:0042447)3.77977518
121positive regulation of fatty acid beta-oxidation (GO:0032000)3.77430543
122* organic acid catabolic process (GO:0016054)3.75165674
123* carboxylic acid catabolic process (GO:0046395)3.75165674
124ethanol oxidation (GO:0006069)3.73871327
125* xenobiotic metabolic process (GO:0006805)3.71624986
126protein-lipid complex subunit organization (GO:0071825)3.70838189
127exogenous drug catabolic process (GO:0042738)3.63999657
128carnitine metabolic process (GO:0009437)3.63407962
129cofactor catabolic process (GO:0051187)3.62707115
130regulation of bile acid biosynthetic process (GO:0070857)3.60456941
131lipoprotein metabolic process (GO:0042157)3.59210271
132linoleic acid metabolic process (GO:0043651)3.54700052
133sterol transport (GO:0015918)3.54342101
134cholesterol transport (GO:0030301)3.54342101
135heme transport (GO:0015886)3.51010857
136positive regulation of blood coagulation (GO:0030194)3.50052437

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse8.51742497
2PPARA_22158963_ChIP-Seq_LIVER_Mouse7.17783502
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.70679618
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.58675179
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.19412144
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.16998992
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.10846466
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.98139376
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.88370080
10TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.06020454
11ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.8298269
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.96879115
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.92930195
14FOXA2_19822575_ChIP-Seq_HepG2_Human1.60108169
15CLOCK_20551151_ChIP-Seq_293T_Human1.58847192
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.56352764
17HTT_18923047_ChIP-ChIP_STHdh_Human1.55727304
18* HNF4A_19822575_ChIP-Seq_HepG2_Human1.37466936
19THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.30681684
20GATA1_22025678_ChIP-Seq_K562_Human1.23485255
21IGF1R_20145208_ChIP-Seq_DFB_Human1.21785625
22ESR1_15608294_ChIP-ChIP_MCF-7_Human1.17863028
23GBX2_23144817_ChIP-Seq_PC3_Human1.16224313
24STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.15939143
25RXRA_24833708_ChIP-Seq_LIVER_Mouse1.12657373
26NFE2_27457419_Chip-Seq_LIVER_Mouse1.09181753
27CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.05618855
28IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.04443931
29PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04317116
30ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01467762
31STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.01184790
32IRF1_19129219_ChIP-ChIP_H3396_Human1.00645964
33ER_23166858_ChIP-Seq_MCF-7_Human1.00597840
34EZH2_27294783_Chip-Seq_NPCs_Mouse1.00230815
35PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.00211953
36CDX2_19796622_ChIP-Seq_MESCs_Mouse0.99447426
37PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.99035385
38MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.95772116
39TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.95277180
40POU3F2_20337985_ChIP-ChIP_501MEL_Human0.93328341
41PIAS1_25552417_ChIP-Seq_VCAP_Human0.92301871
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.92056786
43SUZ12_27294783_Chip-Seq_NPCs_Mouse0.91166801
44AUTS2_25519132_ChIP-Seq_293T-REX_Human0.88368063
45ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.85210585
46SOX2_27498859_Chip-Seq_STOMACH_Mouse0.84432249
47* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82897422
48CRX_20693478_ChIP-Seq_RETINA_Mouse0.82875551
49TCF4_22108803_ChIP-Seq_LS180_Human0.82863285
50ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.82202934
51RARG_19884340_ChIP-ChIP_MEFs_Mouse0.82024603
52ZNF263_19887448_ChIP-Seq_K562_Human0.80957288
53* KLF5_20875108_ChIP-Seq_MESCs_Mouse0.79625188
54* GATA4_25053715_ChIP-Seq_YYC3_Human0.79155573
55KAP1_22055183_ChIP-Seq_ESCs_Mouse0.78836029
56IRF8_22096565_ChIP-ChIP_GC-B_Human0.77006790
57HNFA_21074721_ChIP-Seq_CACO-2_Human0.76077952
58SMAD1_18555785_Chip-Seq_ESCs_Mouse0.75938195
59ZNF274_21170338_ChIP-Seq_K562_Hela0.75618293
60SRY_22984422_ChIP-ChIP_TESTIS_Rat0.75389633
61SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.73993282
62FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.73679203
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.73353213
64CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.71619821
65OCT4_18555785_Chip-Seq_ESCs_Mouse0.71199044
66ETV2_25802403_ChIP-Seq_MESCs_Mouse0.71084806
67Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.70816744
68VDR_22108803_ChIP-Seq_LS180_Human0.70809149
69EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.69972012
70SOX2_19829295_ChIP-Seq_ESCs_Human0.69895891
71NANOG_19829295_ChIP-Seq_ESCs_Human0.69895891
72NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.69607755
73PCGF2_27294783_Chip-Seq_ESCs_Mouse0.69574959
74TCF4_18268006_ChIP-ChIP_LS174T_Human0.69354795
75SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.68809524
76RARA_24833708_ChIP-Seq_LIVER_Mouse0.68738440
77OCT4_21477851_ChIP-Seq_ESCs_Mouse0.68645705
78PHF8_20622853_ChIP-Seq_HELA_Human0.67344477
79NFYA_21822215_ChIP-Seq_K562_Human0.67310107
80SOX2_21211035_ChIP-Seq_LN229_Human0.67292342
81TP53_18474530_ChIP-ChIP_U2OS_Human0.67271243
82ESR2_21235772_ChIP-Seq_MCF-7_Human0.67039457
83RUNX1_27457419_Chip-Seq_LIVER_Mouse0.67010828
84EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.66421538
85CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.66081876
86BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.66005672
87SMAD4_21741376_ChIP-Seq_EPCs_Human0.65795896
88FLI1_27457419_Chip-Seq_LIVER_Mouse0.65227062
89RAC3_21632823_ChIP-Seq_H3396_Human0.65134017
90EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.64391233
91FOXA1_21572438_ChIP-Seq_LNCaP_Human0.64187020
92AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.64105706
93GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.63987894
94NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.63075930
95FOXA1_25329375_ChIP-Seq_VCAP_Human0.62654320
96FOXA1_27270436_Chip-Seq_PROSTATE_Human0.62654320
97MYC_19829295_ChIP-Seq_ESCs_Human0.62300731
98EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.62256656
99FOXH1_21741376_ChIP-Seq_EPCs_Human0.61705255
100SALL4_18804426_ChIP-ChIP_XEN_Mouse0.61482694
101NRF2_20460467_ChIP-Seq_MEFs_Mouse0.60501564
102NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.60501564
103LXR_22292898_ChIP-Seq_THP-1_Human0.59798984
104RAD21_21589869_ChIP-Seq_MESCs_Mouse0.59133325
105RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.58305791
106RARB_24833708_ChIP-Seq_LIVER_Mouse0.58232479
107CEBPB_22108803_ChIP-Seq_LS180_Human0.57307580
108PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.56777508
109GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.55996662
110ESET_19884257_ChIP-Seq_ESCs_Mouse0.51214836
111ERG_21242973_ChIP-ChIP_JURKAT_Human0.51122490
112STAT1_17558387_ChIP-Seq_HELA_Human0.50744773
113FOXA1_25552417_ChIP-Seq_VCAP_Human0.50546740
114MYC_19915707_ChIP-ChIP_AK7_Human0.48840004
115CBP_21632823_ChIP-Seq_H3396_Human0.47763769
116P53_21459846_ChIP-Seq_SAOS-2_Human0.47089554
117PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.47040199
118PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.46574841
119FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.46469834
120EGR1_19032775_ChIP-ChIP_M12_Human0.46291603
121GATA1_19941827_ChIP-Seq_MEL_Mouse0.45975785
122PPAR_26484153_Chip-Seq_NCI-H1993_Human0.45268078
123* GATA1_19941826_ChIP-Seq_K562_Human0.45134502
124AR_20517297_ChIP-Seq_VCAP_Human0.44673654
125TAF15_26573619_Chip-Seq_HEK293_Human0.43857012
126BCAT_22108803_ChIP-Seq_LS180_Human0.42860602
127PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.42395343
128SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.41865121
129FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.41252590
130LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.41124422
131* GATA2_19941826_ChIP-Seq_K562_Human0.40691551
132CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.39875938
133ESR1_20079471_ChIP-ChIP_T-47D_Human0.39341855
134MYC_27129775_Chip-Seq_CORNEA_Mouse0.36956197
135CDX2_20551321_ChIP-Seq_CACO-2_Human0.36873117
136TAF2_19829295_ChIP-Seq_ESCs_Human0.36152889
137SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.35970290
138STAT3_1855785_ChIP-Seq_MESCs_Mouse0.35482354
139SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.35342212
140CDX2_22108803_ChIP-Seq_LS180_Human0.34864335
141GATA6_25053715_ChIP-Seq_YYC3_Human0.34507675
142FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.34476541
143SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.33933943
144ESR1_21235772_ChIP-Seq_MCF-7_Human0.33918059
145STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.33121224
146FOXO3_23340844_ChIP-Seq_DLD1_Human0.33107939
147FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.32835921
148NCOR_22424771_ChIP-Seq_293T_Human0.32799956
149CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.32780215

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.50020397
2MP0005360_urolithiasis7.41014207
3MP0005085_abnormal_gallbladder_physiolo6.13237088
4MP0005365_abnormal_bile_salt6.02684910
5MP0008875_abnormal_xenobiotic_pharmacok5.62506671
6MP0003806_abnormal_nucleotide_metabolis4.21063202
7MP0010329_abnormal_lipoprotein_level3.71327487
8MP0009840_abnormal_foam_cell3.67285848
9MP0003252_abnormal_bile_duct3.59496236
10MP0005083_abnormal_biliary_tract3.23442847
11MP0003195_calcinosis3.00704501
12MP0005332_abnormal_amino_acid2.78018975
13MP0001666_abnormal_nutrient_absorption2.44839632
14MP0003191_abnormal_cellular_cholesterol2.29871870
15MP0004019_abnormal_vitamin_homeostasis2.20088155
16MP0000609_abnormal_liver_physiology2.15561689
17MP0002118_abnormal_lipid_homeostasis2.14513999
18MP0005451_abnormal_body_composition1.96983415
19MP0002909_abnormal_adrenal_gland1.91430357
20MP0002138_abnormal_hepatobiliary_system1.86534837
21MP0005319_abnormal_enzyme/_coenzyme1.77750889
22MP0003868_abnormal_feces_composition1.69966752
23MP0009697_abnormal_copulation1.67030025
24MP0001764_abnormal_homeostasis1.61700912
25MP0005584_abnormal_enzyme/coenzyme_acti1.59938426
26MP0003122_maternal_imprinting1.41935561
27MP0003941_abnormal_skin_development1.40225473
28MP0000604_amyloidosis1.29884398
29MP0003011_delayed_dark_adaptation1.29496969
30MP0003656_abnormal_erythrocyte_physiolo1.23267262
31MP0003186_abnormal_redox_activity1.21928791
32MP0009643_abnormal_urine_homeostasis1.21413136
33MP0000598_abnormal_liver_morphology1.14862342
34MP0003705_abnormal_hypodermis_morpholog1.10865736
35MP0009764_decreased_sensitivity_to1.04255633
36MP0009763_increased_sensitivity_to1.01986576
37MP0005647_abnormal_sex_gland0.98901021
38MP0002254_reproductive_system_inflammat0.97066990
39MP0010368_abnormal_lymphatic_system0.93812228
40MP0001915_intracranial_hemorrhage0.90720469
41MP0009642_abnormal_blood_homeostasis0.87879350
42MP0005636_abnormal_mineral_homeostasis0.85552840
43MP0006036_abnormal_mitochondrial_physio0.83163799
44MP0008469_abnormal_protein_level0.82796258
45MP0005408_hypopigmentation0.82685193
46MP0002078_abnormal_glucose_homeostasis0.82664642
47MP0008995_early_reproductive_senescence0.82379266
48MP0009765_abnormal_xenobiotic_induced0.81059285
49MP0003329_amyloid_beta_deposits0.78630452
50MP0005376_homeostasis/metabolism_phenot0.78011655
51MP0002876_abnormal_thyroid_physiology0.76984744
52MP0002132_abnormal_respiratory_system0.76395765
53MP0003690_abnormal_glial_cell0.75979806
54MP0001661_extended_life_span0.75891337
55MP0002971_abnormal_brown_adipose0.75349465
56MP0009780_abnormal_chondrocyte_physiolo0.73571486
57MP0009053_abnormal_anal_canal0.72015237
58MP0005334_abnormal_fat_pad0.71666691
59MP0005670_abnormal_white_adipose0.71621782
60MP0000639_abnormal_adrenal_gland0.66700359
61MP0004130_abnormal_muscle_cell0.65864812
62MP0005084_abnormal_gallbladder_morpholo0.65286857
63MP0001756_abnormal_urination0.63145346
64MP0005535_abnormal_body_temperature0.62934930
65MP0005448_abnormal_energy_balance0.62694991
66MP0005464_abnormal_platelet_physiology0.61916183
67MP0005266_abnormal_metabolism0.60740147
68MP0002938_white_spotting0.58468620
69MP0002822_catalepsy0.57934409
70MP0008874_decreased_physiological_sensi0.57277189
71MP0003879_abnormal_hair_cell0.54555650
72MP0005220_abnormal_exocrine_pancreas0.54058347
73MP0002282_abnormal_trachea_morphology0.53919097
74MP0002837_dystrophic_cardiac_calcinosis0.53365226
75MP0006035_abnormal_mitochondrial_morpho0.53359348
76MP0003638_abnormal_response/metabolism_0.52693564
77MP0005395_other_phenotype0.50696704
78MP0008872_abnormal_physiological_respon0.48503459
79MP0005248_abnormal_Harderian_gland0.47511023
80MP0008873_increased_physiological_sensi0.47218277
81MP0002136_abnormal_kidney_physiology0.46622300
82MP0004782_abnormal_surfactant_physiolog0.45938641
83MP0003075_altered_response_to0.45547271
84MP0001765_abnormal_ion_homeostasis0.45234159
85MP0003953_abnormal_hormone_level0.44424186
86MP0003436_decreased_susceptibility_to0.43317669
87MP0004883_abnormal_blood_vessel0.42576826
88MP0003718_maternal_effect0.42257976
89MP0000566_synostosis0.42073690
90MP0004142_abnormal_muscle_tone0.41134488
91MP0000249_abnormal_blood_vessel0.40785377
92MP0006082_CNS_inflammation0.39506682
93MP0005379_endocrine/exocrine_gland_phen0.39488844
94MP0003959_abnormal_lean_body0.39479533
95MP0005551_abnormal_eye_electrophysiolog0.38465445
96MP0009672_abnormal_birth_weight0.38431882
97MP0005167_abnormal_blood-brain_barrier0.38105167
98MP0003315_abnormal_perineum_morphology0.37572429
99MP0001243_abnormal_dermal_layer0.37122483
100MP0002168_other_aberrant_phenotype0.36802198
101MP0005666_abnormal_adipose_tissue0.35332825
102MP0009115_abnormal_fat_cell0.35211052
103MP0001853_heart_inflammation0.33792861
104MP0002928_abnormal_bile_duct0.32662291
105MP0003724_increased_susceptibility_to0.32023788
106MP0001324_abnormal_eye_pigmentation0.31873872
107MP0000230_abnormal_systemic_arterial0.31828424
108MP0002090_abnormal_vision0.30857123
109MP0002970_abnormal_white_adipose0.30852659
110MP0001984_abnormal_olfaction0.30643285
111MP0003950_abnormal_plasma_membrane0.30603658
112MP0005187_abnormal_penis_morphology0.29640738
113MP0000647_abnormal_sebaceous_gland0.29595489
114MP0003632_abnormal_nervous_system0.29209798
115MP0005164_abnormal_response_to0.27832007
116MP0003121_genomic_imprinting0.26769537
117MP0001845_abnormal_inflammatory_respons0.26537230
118MP0003183_abnormal_peptide_metabolism0.26404224
119MP0002089_abnormal_postnatal_growth/wei0.26147805
120MP0002249_abnormal_larynx_morphology0.24562370
121MP0005410_abnormal_fertilization0.24561477
122MP0003633_abnormal_nervous_system0.23597586
123MP0001881_abnormal_mammary_gland0.23548919
124MP0005166_decreased_susceptibility_to0.22856014
125MP0005595_abnormal_vascular_smooth0.21215860
126MP0002269_muscular_atrophy0.20789547
127MP0003300_gastrointestinal_ulcer0.20379054
128MP0005058_abnormal_lysosome_morphology0.18673653

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.72897971
2Abnormality of aromatic amino acid family metabolism (HP:0004338)7.58765241
3Hypobetalipoproteinemia (HP:0003563)6.86527259
4Intrahepatic cholestasis (HP:0001406)6.75299479
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.64617119
6Prolonged partial thromboplastin time (HP:0003645)6.56281847
7Xanthomatosis (HP:0000991)6.32902763
8Hyperlipoproteinemia (HP:0010980)6.14229296
9Hypolipoproteinemia (HP:0010981)5.10385477
10Joint hemorrhage (HP:0005261)4.98695526
11Hyperammonemia (HP:0001987)4.71147586
12Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.69073076
13Hypoalphalipoproteinemia (HP:0003233)4.46223281
14Abnormality of methionine metabolism (HP:0010901)4.43623361
15Hyperglycinemia (HP:0002154)4.42869720
16Ketosis (HP:0001946)4.41708862
17Abnormality of the common coagulation pathway (HP:0010990)4.37801716
18Epidermoid cyst (HP:0200040)4.25714424
19Abnormality of sulfur amino acid metabolism (HP:0004339)4.24840575
20Abnormality of aspartate family amino acid metabolism (HP:0010899)4.21249330
21Abnormality of glutamine family amino acid metabolism (HP:0010902)4.12429992
22Hyperglycinuria (HP:0003108)4.11845064
23Abnormality of glycine metabolism (HP:0010895)4.07224480
24Abnormality of serine family amino acid metabolism (HP:0010894)4.07224480
25Hypoglycemic coma (HP:0001325)4.03482882
26Hypercholesterolemia (HP:0003124)3.93641718
27Abnormality of pyrimidine metabolism (HP:0004353)3.84618347
28Renal salt wasting (HP:0000127)3.73858949
29Fat malabsorption (HP:0002630)3.70469883
30Abnormality of the intrinsic pathway (HP:0010989)3.63401688
31Recurrent gram-negative bacterial infections (HP:0005420)3.53292801
32Conjugated hyperbilirubinemia (HP:0002908)3.47927447
33Hyperbilirubinemia (HP:0002904)3.45962373
34Complement deficiency (HP:0004431)3.43492983
35Abnormality of fatty-acid metabolism (HP:0004359)3.41266699
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.32841220
37Delayed CNS myelination (HP:0002188)3.32742984
38Ketoacidosis (HP:0001993)3.24452189
39Abnormality of nucleobase metabolism (HP:0010932)3.09435225
40Sex reversal (HP:0012245)3.08047527
41Abnormal sex determination (HP:0012244)3.08047527
42Abnormality of serum amino acid levels (HP:0003112)3.06499456
43Hepatocellular carcinoma (HP:0001402)2.93142513
44Metabolic acidosis (HP:0001942)2.90952740
45Spontaneous abortion (HP:0005268)2.89805253
46Vascular calcification (HP:0004934)2.88255808
47Myocardial infarction (HP:0001658)2.78811465
48Dicarboxylic aciduria (HP:0003215)2.76768974
49Abnormality of dicarboxylic acid metabolism (HP:0010995)2.76768974
50Abnormality of purine metabolism (HP:0004352)2.71843664
51Steatorrhea (HP:0002570)2.67366931
52Lethargy (HP:0001254)2.66457997
53Glomerulonephritis (HP:0000099)2.65486624
54Skin nodule (HP:0200036)2.62723888
55Osteomalacia (HP:0002749)2.60553055
56Hypochromic microcytic anemia (HP:0004840)2.60151713
57Cardiovascular calcification (HP:0011915)2.56825584
58Hypoglycemic seizures (HP:0002173)2.55198389
59Malnutrition (HP:0004395)2.52773324
60Spastic diplegia (HP:0001264)2.52094899
61Arthropathy (HP:0003040)2.50922958
62Abnormality of complement system (HP:0005339)2.49058140
63Reduced antithrombin III activity (HP:0001976)2.45959559
64Acanthocytosis (HP:0001927)2.45355715
65Cerebral edema (HP:0002181)2.43843570
66Mitral stenosis (HP:0001718)2.42657825
67Menorrhagia (HP:0000132)2.39852823
68Irritability (HP:0000737)2.39121567
69Abnormal gallbladder morphology (HP:0012437)2.38928866
70Amyloidosis (HP:0011034)2.36723519
71Gout (HP:0001997)2.32286667
72Cholelithiasis (HP:0001081)2.31848187
73Esophageal varix (HP:0002040)2.27064443
74Abnormality of vitamin metabolism (HP:0100508)2.26439362
75Fair hair (HP:0002286)2.21140591
76Late onset (HP:0003584)2.19280272
77Gingival bleeding (HP:0000225)2.18868909
78Purpura (HP:0000979)2.16186803
79Generalized aminoaciduria (HP:0002909)2.15444233
80Abnormal gallbladder physiology (HP:0012438)2.15389627
81Cholecystitis (HP:0001082)2.15389627
82Hyperphosphaturia (HP:0003109)2.14878350
83Neonatal onset (HP:0003623)2.14664362
84Vomiting (HP:0002013)2.14606237
85Azoospermia (HP:0000027)2.14219008
86Hyperaldosteronism (HP:0000859)2.13140022
87Pancreatitis (HP:0001733)2.11656229
88Brushfield spots (HP:0001088)2.10924955
89Poikilocytosis (HP:0004447)2.08569468
90Thrombophlebitis (HP:0004418)2.08172285
91Hyperinsulinemic hypoglycemia (HP:0000825)2.07265077
92Cerebral palsy (HP:0100021)2.05515207
93Enlarged kidneys (HP:0000105)2.04820534
94Abnormality of proline metabolism (HP:0010907)2.03359652
95Hydroxyprolinuria (HP:0003080)2.03359652
96Hemorrhage of the eye (HP:0011885)2.03250978
97Opisthotonus (HP:0002179)2.00776948
98Alkalosis (HP:0001948)1.99048583
99Potter facies (HP:0002009)1.99007019
100Facial shape deformation (HP:0011334)1.99007019
101Hypophosphatemic rickets (HP:0004912)1.91004637
102Rickets (HP:0002748)1.90443908
103Sensorimotor neuropathy (HP:0007141)1.89119436
104Bifid scrotum (HP:0000048)1.88797612
105Reticulocytosis (HP:0001923)1.87907499
106Nephritis (HP:0000123)1.87346408
107Renal cortical cysts (HP:0000803)1.86747284
108Systemic lupus erythematosus (HP:0002725)1.85711515
109Abnormality of the gallbladder (HP:0005264)1.85113916
110Abnormal cartilage morphology (HP:0002763)1.84399022
111Abnormality of iron homeostasis (HP:0011031)1.84343276
112Status epilepticus (HP:0002133)1.83999676
113Bile duct proliferation (HP:0001408)1.82520478
114Abnormal biliary tract physiology (HP:0012439)1.82520478
115Abnormality of transition element cation homeostasis (HP:0011030)1.81302064
116Joint swelling (HP:0001386)1.80538096
117Proximal tubulopathy (HP:0000114)1.80137857
118Glycosuria (HP:0003076)1.79935279
119Abnormality of urine glucose concentration (HP:0011016)1.79935279
120Increased serum pyruvate (HP:0003542)1.78821876
121Pulmonary embolism (HP:0002204)1.78493738
122Abnormal urine phosphate concentration (HP:0012599)1.72594191
123Mucopolysacchariduria (HP:0008155)1.69745800
124Urinary glycosaminoglycan excretion (HP:0003541)1.69745800
125Clitoromegaly (HP:0000057)1.69679336
126Decreased circulating renin level (HP:0003351)1.64899556
127Elevated alkaline phosphatase (HP:0003155)1.63387793
128Abnormal enzyme/coenzyme activity (HP:0012379)1.57427928
129Neonatal hypoglycemia (HP:0001998)1.56800614

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.69634287
2SIK15.19954119
3AKT34.50522891
4FGFR44.30386798
5ERN13.62680583
6PKN23.43821398
7INSRR2.86245249
8TAOK32.67092660
9FLT32.50053381
10MAP2K42.36928274
11ACVR1B2.36367822
12PIK3CA2.34057076
13WNK42.25177626
14PIK3CG2.21016133
15TRIB32.08632120
16MST1R2.06498381
17DAPK21.99460177
18WNK31.84532903
19TYK21.73816907
20NTRK31.63942957
21KDR1.60225298
22MAP3K121.51253908
23PTK61.50777388
24ABL21.43318913
25FGFR21.39189312
26MAP4K21.37267095
27CAMKK21.36249155
28ADRBK21.33430753
29BMPR1B1.32847682
30CDK71.32501109
31LATS11.28747888
32PINK11.26096795
33FRK1.23765124
34MAPK111.18522421
35CASK1.18331219
36MAP2K31.16840710
37ERBB41.15386571
38PRKAA21.11435989
39JAK21.09257366
40GRK51.08679412
41MAP3K21.06678407
42MAPKAPK31.06047168
43FER1.04379101
44GRK61.03560197
45MAPK41.03465516
46NEK91.00153178
47MAP3K70.99488278
48TBK10.97983675
49SGK10.95687696
50EPHA40.95476330
51PRKCZ0.92955955
52CSK0.92804786
53JAK10.92170947
54MAP3K100.91224285
55MAP3K140.90028188
56TIE10.89086929
57MAP3K30.87155556
58MAP3K110.87093388
59MAPK120.85554432
60CAMK1D0.84785489
61MYLK0.83800974
62MET0.83669251
63NLK0.83033002
64EPHB10.82750743
65CDK60.81527941
66STK390.80909248
67CSNK1D0.80858815
68DYRK1B0.80777489
69PRKACG0.79878237
70PRKG10.78316264
71TGFBR20.74203061
72MAP2K60.69288447
73AKT20.67936646
74RIPK10.66795109
75GSK3A0.65640564
76EIF2AK30.61251409
77CSF1R0.61033496
78CSNK1E0.60788782
79SGK30.59932943
80RET0.59400936
81PRKAA10.59387899
82CSNK1A10.58378257
83PTK20.57480004
84RPS6KA30.57214875
85PRKCQ0.56435791
86MAPK70.55382561
87PDPK10.54973059
88TAOK20.54821475
89PRKCB0.54768068
90STK38L0.54550694
91CSNK1G10.53738538
92STK160.53259768
93MAP3K40.53145815
94DYRK20.52866441
95MAPK30.51518097
96PRKCE0.51097365
97ERBB20.50704088
98BCR0.48759668
99EPHA30.48723494
100TYRO30.48676385
101TLK10.47352836
102PDK20.46900740
103GRK10.46594232
104MAP3K130.46222030
105PRKCG0.45840596
106RPS6KB10.45238766
107PDK10.44836224
108IGF1R0.44620650
109BRSK20.43982132
110FGFR30.43432809
111EIF2AK10.43296027
112CAMK2G0.42747116
113SGK20.42288807
114IKBKE0.42026125
115MUSK0.40674769
116ZAK0.40142590
117PRKACB0.39238996
118MAP3K50.38998340
119MAP2K10.38821269
120CDK40.37904437
121MAP3K60.37747035
122CSNK1G20.37542863
123PDK40.35745885
124PDK30.35745885
125ICK0.34456146
126SGK2230.34010123
127SGK4940.34010123
128CSNK1G30.33607561
129CAMK40.33162248
130CAMKK10.32399826
131CAMK1G0.31346534
132PBK0.30110108
133MTOR0.29132736
134PRKCA0.27404206
135MAP3K10.25944393
136MAPK150.25760740
137FGFR10.25077566
138CSNK1A1L0.23984005
139LATS20.23254469
140BLK0.23037950
141IRAK30.20561669
142MAP2K20.20366521
143EGFR0.19941456
144PRKACA0.19823548

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.98555329
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.69733128
3Nitrogen metabolism_Homo sapiens_hsa009103.64597934
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.25772045
5Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010403.17090327
6Arginine biosynthesis_Homo sapiens_hsa002202.98506728
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.64585646
8Tryptophan metabolism_Homo sapiens_hsa003802.60271700
9Fatty acid degradation_Homo sapiens_hsa000712.51927040
10Complement and coagulation cascades_Homo sapiens_hsa046102.46935842
11Pentose and glucuronate interconversions_Homo sapiens_hsa000402.46721156
12Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.42669545
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.42541724
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.31898111
15Butanoate metabolism_Homo sapiens_hsa006502.25944657
16Steroid hormone biosynthesis_Homo sapiens_hsa001402.05740022
17Propanoate metabolism_Homo sapiens_hsa006402.03709052
18Peroxisome_Homo sapiens_hsa041462.00060003
19* Chemical carcinogenesis_Homo sapiens_hsa052041.98638376
20Histidine metabolism_Homo sapiens_hsa003401.94361179
21* Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.94222297
22Fatty acid metabolism_Homo sapiens_hsa012121.92444225
23Drug metabolism - other enzymes_Homo sapiens_hsa009831.92286055
24PPAR signaling pathway_Homo sapiens_hsa033201.89473548
25Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.88906128
26beta-Alanine metabolism_Homo sapiens_hsa004101.80133059
27Retinol metabolism_Homo sapiens_hsa008301.78042464
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.73874507
29Staphylococcus aureus infection_Homo sapiens_hsa051501.73721298
30Caffeine metabolism_Homo sapiens_hsa002321.67754303
31Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.67391201
32Selenocompound metabolism_Homo sapiens_hsa004501.54096731
33Phenylalanine metabolism_Homo sapiens_hsa003601.53498185
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50991673
35Fatty acid elongation_Homo sapiens_hsa000621.47351046
362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.46742370
37Pyruvate metabolism_Homo sapiens_hsa006201.39430842
38* Bile secretion_Homo sapiens_hsa049761.39321479
39Sulfur metabolism_Homo sapiens_hsa009201.36541025
40Tyrosine metabolism_Homo sapiens_hsa003501.32625350
41Starch and sucrose metabolism_Homo sapiens_hsa005001.29000260
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.24165004
43ABC transporters_Homo sapiens_hsa020101.20199354
44Fat digestion and absorption_Homo sapiens_hsa049751.17529689
45Steroid biosynthesis_Homo sapiens_hsa001001.17314702
46Biosynthesis of amino acids_Homo sapiens_hsa012301.17175340
47Carbon metabolism_Homo sapiens_hsa012001.13908232
48Folate biosynthesis_Homo sapiens_hsa007901.10756163
49Cyanoamino acid metabolism_Homo sapiens_hsa004601.07768116
50Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.06874791
51Arginine and proline metabolism_Homo sapiens_hsa003301.03094167
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.92316456
53Maturity onset diabetes of the young_Homo sapiens_hsa049500.87303655
54Vitamin digestion and absorption_Homo sapiens_hsa049770.86904074
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.85967393
56Lysine degradation_Homo sapiens_hsa003100.84403038
57Sulfur relay system_Homo sapiens_hsa041220.84264071
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.79072699
59One carbon pool by folate_Homo sapiens_hsa006700.73988171
60Glycerolipid metabolism_Homo sapiens_hsa005610.73943337
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.69956603
62Pentose phosphate pathway_Homo sapiens_hsa000300.57543045
63Fatty acid biosynthesis_Homo sapiens_hsa000610.57528894
64Glutathione metabolism_Homo sapiens_hsa004800.56783741
65Vitamin B6 metabolism_Homo sapiens_hsa007500.52700540
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.50171017
67Metabolic pathways_Homo sapiens_hsa011000.45090627
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35095292
69Aldosterone synthesis and secretion_Homo sapiens_hsa049250.28891634
70alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.28830645
71Linoleic acid metabolism_Homo sapiens_hsa005910.28264748
72Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.26254285
73Galactose metabolism_Homo sapiens_hsa000520.23795733
74Insulin resistance_Homo sapiens_hsa049310.22687941
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.21699862
76Fructose and mannose metabolism_Homo sapiens_hsa000510.20571373
77Mineral absorption_Homo sapiens_hsa049780.13487829
78Glycerophospholipid metabolism_Homo sapiens_hsa005640.13062788
79Glucagon signaling pathway_Homo sapiens_hsa049220.08982771
80Sphingolipid metabolism_Homo sapiens_hsa006000.02970343
81Other glycan degradation_Homo sapiens_hsa005110.01819233
82AMPK signaling pathway_Homo sapiens_hsa041520.01708970
83Serotonergic synapse_Homo sapiens_hsa047260.00960675
84Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2591679
85Pertussis_Homo sapiens_hsa05133-0.2582258
86Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014-0.2554276
87Ether lipid metabolism_Homo sapiens_hsa00565-0.2475731
88Type II diabetes mellitus_Homo sapiens_hsa04930-0.2437615
89Hepatitis C_Homo sapiens_hsa05160-0.2401494
90Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2347520
91Regulation of autophagy_Homo sapiens_hsa04140-0.2230964
92Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2115718
93Circadian rhythm_Homo sapiens_hsa04710-0.2081719
94Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1936204
95Protein digestion and absorption_Homo sapiens_hsa04974-0.1839908
96Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1838526
97Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1836134
98Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1765879
99Renin-angiotensin system_Homo sapiens_hsa04614-0.1557193
100Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563-0.1547974
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1476916
102Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.1445203
103African trypanosomiasis_Homo sapiens_hsa05143-0.1227310
104N-Glycan biosynthesis_Homo sapiens_hsa00510-0.1085792
105Insulin signaling pathway_Homo sapiens_hsa04910-0.1030365
106Prion diseases_Homo sapiens_hsa05020-0.0975875
107Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0968883
108Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0353127
109Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0268041
110Systemic lupus erythematosus_Homo sapiens_hsa05322-0.0164288

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